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WPQDADSPSQSHEAHGAPGLAAQRGVTAARDAVCAAVSPLLNDRAGLRLSTVFVGAAGAATAPEAARALA AELLAGLPADEVAVTSDAVTAHAGALGARPGVVLSVGTGSVAVGVGADGTFARVGGWGPWLGDEGGGAWI GTAGLRAALHAHDGRGPATQLLAMATARFGDLQQLPATVEAQGNPARTSASFAPDVARAAESGDPVAAGI LADAATALASAVLTTTLRIDPRNRLPVAITGGLVRLGEPLLRPLRTALSAESPQTTLALPLGDSLHGAHL LSRDLTTPHEAHIARVRHTSTQSHPAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0191 | - | - | 100% (309) | BadF/BadG/BcrA/BcrD ATPase family protein |
| M. smegmatis MC2 155 | MSMEG_0512 | - | 2e-21 | 32.43% (259) | BadF/BadG/BcrA/BcrD ATPase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1431c | PE_PGRS25 | 7e-05 | 27.60% (192) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 6e-06 | 33.33% (156) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2352c | PPE38 | 4e-05 | 26.78% (183) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0364c | - | 3e-16 | 34.85% (198) | ATPase, BadF/BadG/BcrA/BcrD type |
| M. marinum M | MMAR_1405 | - | 2e-05 | 31.68% (161) | hypothetical protein MMAR_1405 |
| M. avium 104 | MAV_4602 | - | 2e-06 | 32.08% (159) | O-succinylbenzoic acid--CoA ligase |
| M. thermoresistible (build 8) | TH_4374 | - | 1e-05 | 28.85% (253) | PUTATIVE glucokinase |
| M. ulcerans Agy99 | MUL_1208 | - | 7e-05 | 31.31% (198) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-05 | 31.97% (147) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK -------------------------------MVTFGGGATPTPTSLGAAA
Mvan_1264|M.vanbaalenii_PYR-1 MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASL
Mb1431c|M.bovis_AF2122/97 --------------------------------MSF---LFAQPEMLGAAA
Rv2352c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1208|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M ------------------------------------MPPKPTSPHASEIL
MAV_4602|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VDLSGTSCGLICNGQDGTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGL
Mvan_1264|M.vanbaalenii_PYR-1 VDLSGTSCGLICNGQDGTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGL
Mb1431c|M.bovis_AF2122/97 TDLASIGS------------------------------------------
Rv2352c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1208|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M QNYWEETLEPADLMRRSVEMTKLSGQLIAASEDGQVAAIRLLNHGQGDLA
MAV_4602|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK FGGNGGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG
Mvan_1264|M.vanbaalenii_PYR-1 FGGNGGNGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG
Mb1431c|M.bovis_AF2122/97 --------------------------------------AISTANAAAAAA
Rv2352c|M.tuberculosis_H37Rv -------------------------------------MILDFSWLPPEIN
MUL_1208|M.ulcerans_Agy99 ---------------------------------MAVAAGPIWIASPPEVH
MSMEG_0191|M.smegmatis_MC2_155 ------------------------------------------MWPQDADS
MAB_0364c|M.abscessus_ATCC_199 ------------------------------------MKFGVTVGIDIGGS
MMAR_1405|M.marinum_M DVISTAWTKYFVTVGLVGAQVGQAGAYLSAWANALGAMLAEMSGVVDWTE
MAV_4602|M.avium_104 ----------------------------------------------MLDG
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAGAVG
Mvan_1264|M.vanbaalenii_PYR-1 APGVAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAGAVG
Mb1431c|M.bovis_AF2122/97 TTRVL-AAGADEVSAAVAALFSGHAQTYQALSTQAAAFHQQIVQTLTSTA
Rv2352c|M.tuberculosis_H37Rv SARIYAGAGSGPLFMAAAAWEGLAADLRASASSFDAVIAGLAAGPWSGPA
MUL_1208|M.ulcerans_Agy99 SAMLSSGPGPASLLAAAGVWSALSAEYALTAAELSEVLAAVQAGAWQGPS
MSMEG_0191|M.smegmatis_MC2_155 PSQSHEAHGAPGLAAQRGVTAARDAVCAAVSPLLNDRAGLRLSTVFVGAA
MAB_0364c|M.abscessus_ATCC_199 KTRAVAVAGGRVIGDALAGSANLQSVTEEQAKAVFTDIFSRLNRSDISRV
MMAR_1405|M.marinum_M SAITALEASRPAVEAAGQDVDQLIEQIKTEAQSQIAAISSAAMGVLAAVP
MAV_4602|M.avium_104 RDSALVVLGPPGDRESATLRAGLRVGEPVDDDVALVAATSGTTGAPKGAM
TH_4374|M.thermoresistible__bu --VLTLTLDIGGTKLAAGLVDGDGGLVHHTHAATPGGDAEAVWTVLAGLI
. .
Mflv_5091|M.gilvum_PYR-GCK SAGAAGEAG-ETGTWGNAGLPGKAGDAGGAGAVGAAGAAGTVGTAGATGG
Mvan_1264|M.vanbaalenii_PYR-1 SAGTAGSAG-APGVWGNAGLPGAAGAAGGAGAIGTAGVAGAAGTAGATGG
Mb1431c|M.bovis_AF2122/97 GAYASAEAA-NVEQQLLGAINAPTMALLGRPLIG----------HGADGA
Rv2352c|M.tuberculosis_H37Rv SVAMAGAAA-PYVGWLSAAAGQAELSAG----------------------
MUL_1208|M.ulcerans_Agy99 GFQYVAAHL-PYVAWLLQASADGAGKAA----------------------
MSMEG_0191|M.smegmatis_MC2_155 GAATAPEAARALAAELLAGLPADEVAVT----------------------
MAB_0364c|M.abscessus_ATCC_199 SAGSAGVDTAEGAQTLIRLLRPYAPDAEIT--------------------
MMAR_1405|M.marinum_M SWAASIPVSMSIPHSGIQGPCPATTTGTDGTPTGGVTGPGQGAPPGRSAG
MAV_4602|M.avium_104 LTAAALRASATATHARLGGPGSWLLALP----------------------
TH_4374|M.thermoresistible__bu DDALTRAGG-RVRAVGVGSAGPIDLTAG----------------------
Mflv_5091|M.gilvum_PYR-GCK TGTGANGGAGGVGGVGGTGAAGAAGGAGGLGETGTTG-GAGGVGGQGTAG
Mvan_1264|M.vanbaalenii_PYR-1 TGVGGNGGAGQAGGIGGTGAAGAAGQAGTAGETGVTG-GVGGIGGQGTEG
Mb1431c|M.bovis_AF2122/97 PGTGQAGGAG--------GILYGNGGNGGSGATGQAG-GAGGAAG---LI
Rv2352c|M.tuberculosis_H37Rv --------------------QATAAATAFEAALAATV-HPAAVTANRVLL
MUL_1208|M.ulcerans_Agy99 --------------------EHEAAAVAYSGALAAMP-TLTELGANHALH
MSMEG_0191|M.smegmatis_MC2_155 ----------------------SDAVTAHAGALGARPGVVLSVGTGSVAV
MAB_0364c|M.abscessus_ATCC_199 ---------------------AVHDTQLVLAAGGLTAGIAVISGTGSVAW
MMAR_1405|M.marinum_M GVIGPGQVGSAAPLGNAGGVKGPGSGGDPVPGQAGSVTGPGQASTAPAAL
MAV_4602|M.avium_104 ---------------------------AHHIAGVQVLVRSLLAGSTPVEL
TH_4374|M.thermoresistible__bu ----------------------TVSPINLTAWSRFPLTERVSAALPGVPV
Mflv_5091|M.gilvum_PYR-GCK GTGGVGGIGGAGSTGAVGGVGGKGIQGGQGLQGGKGGDGGAGGKGGDADS
Mvan_1264|M.vanbaalenii_PYR-1 GTGGVGGVGGVGATGGAGGVGGKGIQGGQGLQGGQGGDGGTGGTGGDATS
Mb1431c|M.bovis_AF2122/97 GHGGAGGLGGTGASGGAGGAGG-----------WLWGNGGAGGNGG----
Rv2352c|M.tuberculosis_H37Rv GALVATNILGQNTP-------------------------AIAATEFDYVE
MUL_1208|M.ulcerans_Agy99 GVLVATNFFGLNAIP-------------------------IALNEADYVR
MSMEG_0191|M.smegmatis_MC2_155 GVGADGTFARVGGWG------------------------PWLGDEGGGAW
MAB_0364c|M.abscessus_ATCC_199 GKRADGAVARVGGWG------------------------YLLGDDGSGYG
MMAR_1405|M.marinum_M NSGPAGGVLGPASGTSSSAPKAG----------------GVSGGSVSGSS
MAV_4602|M.avium_104 DVSRGFDVTQLPAATR------------------------ALGTGRRYAS
TH_4374|M.thermoresistible__bu RLGGDGLCMAMGEQWR--------------------------GAGRGARF
Mflv_5091|M.gilvum_PYR-GCK MGSAGATGGKGGNGGNGGRGGLFGKGGNAGNGADGGTGGAGGAGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 MGEAGATGGKGGNGGNGGRGSLFGRGGNAGNGGNGGTGGNGGNGGTGGTG
Mb1431c|M.bovis_AF2122/97 VGVAGDPGGVGGAGGAGGAAGLWGSGG------SGGTGGQGGVG--GGKS
Rv2352c|M.tuberculosis_H37Rv MWAQDVGAMVGYHAGAAAVAETL-------------TPFSVPPLDLAGLA
MUL_1208|M.ulcerans_Agy99 MWVQAATTMGLYQATAGAALASAPRTGPPPK-VVNPGGGQVAHLAADAAR
MSMEG_0191|M.smegmatis_MC2_155 IGTAGLRAALHAHDGRGP----------------------------ATQL
MAB_0364c|M.abscessus_ATCC_199 VSRSAVRHALSLSDRGDAP----------------------------DAL
MMAR_1405|M.marinum_M GASTSASPPVQAHSTATPTSGTPSTTTGHSNSGSGAGTEPSASATPPDAQ
MAV_4602|M.avium_104 LVAVQLAKALGDPAATAALAELDAVLLG------------------GGPA
TH_4374|M.thermoresistible__bu VLGIVVSTGVGGGLVLDGMP----------------------------YQ
Mflv_5091|M.gilvum_PYR-GCK GAGGTGGTGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GNGGTGGTGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGT
Mb1431c|M.bovis_AF2122/97 GDGGTGGIGGAG--GGGGWLHGDGGAGGHGGQGGTGVS--SGGNGGAGGT
Rv2352c|M.tuberculosis_H37Rv SQAGAQLTGMATSVSAALSPIAEGAVEGVPAVVAAAQSVAAGLPVDAALQ
MUL_1208|M.ulcerans_Agy99 AQSGAAAAGGSDPWQLLWQLLQYLWNAYTGFNTWMFDLIWEFLQDPIGNT
MSMEG_0191|M.smegmatis_MC2_155 LAMATARFGDLQQLPATVEAQGNPARTSASFAPDVARAAESGDPVAAGIL
MAB_0364c|M.abscessus_ATCC_199 SRKFAAECGVTEPAQLLDHFYAHSERRYWAKMAGLVFDLAATGDKAAQVI
MMAR_1405|M.marinum_M LISQSSAAATAPQGLAAARAVAVVSAACGAEVAPVAGSALGPAAASAPLS
MAV_4602|M.avium_104 PRPVLQAAAAAGITVVRSYGMSETAGGCVYDGVPLDGVRVRVSDGRIALS
TH_4374|M.thermoresistible__bu GRTGNAGHVGHVVVDPRGVACSCGGRGCVETMAAGPAMVRWARANGWNAP
Mflv_5091|M.gilvum_PYR-GCK GGKG-GTGGTGGAGGTGGDGGTGGTGGTGGTGGTGGTGGTGGAGDGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GGKG-GTGGTGGDGGTGGTGGTGGTGGTGGTGGTGGTGGTGGAGDGLGGT
Mb1431c|M.bovis_AF2122/97 GGDGRGLSGSGGAGGHGGQTGVGGKVGENNFGGAGGAGGTG----GLIGN
Rv2352c|M.tuberculosis_H37Rv VGQAAAYPASMLIGPMMQLAQMGTTANTAGLAGAEAAGLAAADVPTFAGD
MUL_1208|M.ulcerans_Agy99 IKIIIAFLTNPLQAIITYGPLLFALSYQIFFNLVGWPTWALILSSPFLLP
MSMEG_0191|M.smegmatis_MC2_155 ADAATALASAVLTTTLRIDP-----RNRLPVAITGGLVRLGEPLLRPLRT
MAB_0364c|M.abscessus_ATCC_199 TRQTAIDLAALIEG---------------------VCLRLGPGLPVVLGG
MMAR_1405|M.marinum_M AAPLSALASAPAAAGAVPAPSPGPPSPPVSPLSPAASGNAVAPPSVAGAQ
MAV_4602|M.avium_104 GATLAKGYRNPVDPDPFADPGWFLTDDLGAVDDDGVLTVFGRADDAISTG
TH_4374|M.thermoresistible__bu PDADAEDLAAAAAAGVPVAVRAYRRGADALAAAISSVAAVCDLDLVVIGG
Mflv_5091|M.gilvum_PYR-GCK GGTG-GTGGQGGQG-GQGGTG--GTGGQGGLGGGGGTGGQGGTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 GGTG-GTGGFGGQG-GQGGTG--GTGGQGGLGGVGGTGGTGGTGGTGGQG
Mb1431c|M.bovis_AF2122/97 GGAG-GTGGKGGDGFGVFGKG--GAGGTGGRGGAAGLIGDAGTGGTGGKG
Rv2352c|M.tuberculosis_H37Rv IASGTGLGGAGGLGAGMSAEL--GKARLVG----AMSVPPTWEGSVPARM
MUL_1208|M.ulcerans_Agy99 AALGLALSAIAFTPIQIAAEVPAAAAPLAAAAVTAKSVFPAASLASPGTG
MSMEG_0191|M.smegmatis_MC2_155 ALSAESPQTTLALPLGDSLHG-------------AHLLSRDLTTPHEAHI
MAB_0364c|M.abscessus_ATCC_199 GLLVNQPGLVADIIERTRTSG----------------VSDVAVLQREPVF
MMAR_1405|M.marinum_M PAAGTGLRATTAAGPAPAPGSVATTHAAAPSSRPVSNWSPHDRDPFSPPA
MAV_4602|M.avium_104 GLTVLPQPVEAALCTHPAVAD------SAVFGLPDDRLGQRVVAAIVLRD
TH_4374|M.thermoresistible__bu GVARSGPVLFDPLAEALTTYT-------------GLSFLRGLRVVPARLG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTGGTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTGGTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG
Mb1431c|M.bovis_AF2122/97 GTAGEDGTGGNGGTGGNGGAAVLIGNGGGGGAGGNGGAGNDGTPG--NGG
Rv2352c|M.tuberculosis_H37Rv ASSAMAGLGAMPAEVPAAG----GPMGMMPMPMGMGGAG-AGMPAGMMGR
MUL_1208|M.ulcerans_Agy99 SAGAPASGAGAGAPGTAPPGPGAPAPASFLYAVGGSGDWGPSLGPTVGGR
MSMEG_0191|M.smegmatis_MC2_155 ARVRHTSTQSHPAVR-----------------------------------
MAB_0364c|M.abscessus_ATCC_199 GALALAGVDVEGLESA----------------------------------
MMAR_1405|M.marinum_M AGVAGDGATGPIISPLTGGCDPLVVPAVLIPPTSSSAALGDQDLATVRSV
MAV_4602|M.avium_104 GRAAPSPDALRAHLSRTLDATAAPREVHVVAALPRRGIGKVDRAALVRRF
TH_4374|M.thermoresistible__bu ATAGLIGAARLAISAC----------------------------------
.
Mflv_5091|M.gilvum_PYR-GCK AGGAGGQAGTAGKGGLFGGSGSAGKAGATGAAGASGGKGAQGATGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGGQAGVAGKGGLFGGSGSAGTAGVTGASGASGGKGAQGATGAQGAT
Mb1431c|M.bovis_AF2122/97 GGGVGGTG-----GTLFGQPGQPGPPGQPGPA------------------
Rv2352c|M.tuberculosis_H37Rv GGAN--------PHVVQARPSVVPRVGIG---------------------
MUL_1208|M.ulcerans_Agy99 SGAKAPAVTIPAAGAAAASRASARSRRRRRTEMRDYGDEFLDMDANGVTG
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M VEAAGGASQVHWAAGMVVTSGRRQVVLTSDRG-RSWVPAEAFLPADVITP
MAV_4602|M.avium_104 AGGGEQ--------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAQGATGATGAAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGS
Mvan_1264|M.vanbaalenii_PYR-1 GAQGATGATGASGAQGSAGSAGSAGVAGSAGTTGAQGSAGTNGANGANGS
Mb1431c|M.bovis_AF2122/97 --------------------------------------------------
Rv2352c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1208|M.ulcerans_Agy99 PAATDDAARASERGAGQFGFAGTVSTEAVLQAAGLTELAVDEFGNGPRMP
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M WSHEQSSRWGGLLDPARVIVEYAAAAGGRLTALASTFSGAPAVAAGIPWT
MAV_4602|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATGAAGEDGDAGSGGSGINGGAGGAGGAGGEGGEGG
Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATGAAGDAGDPGSEAVDINGGAGGAGGAGGEGGEGG
Mb1431c|M.bovis_AF2122/97 --------------------------------------------------
Rv2352c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1208|M.ulcerans_Agy99 MVPGSWDSPQEGREDGLQSE------------------------------
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M LVDGTDRAHPELLSGPVVTRFELQVSPERRRAVKHITDPVKQRVQVLWLA
MAV_4602|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK DGGKGGAGAEGGAGGGGGAGGSGAGGAGGAGGSGGSGGSGGSGGSGGAAG
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGGDGSEGGAGGSGGAGGSGTGGAGGAGGSGGSGGSGGAGGSGGAAG
Mb1431c|M.bovis_AF2122/97 --------------------------------------------------
Rv2352c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1208|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0191|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0364c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1405|M.marinum_M LSADETAGSLGTRGRMLSLFRDHLGRIDRPRWVASLPWEQLEDEHHRLCV
MAV_4602|M.avium_104 --------------------------------------------------
TH_4374|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK DSDD---
Mvan_1264|M.vanbaalenii_PYR-1 DSD----
Mb1431c|M.bovis_AF2122/97 -------
Rv2352c|M.tuberculosis_H37Rv -------
MUL_1208|M.ulcerans_Agy99 -------
MSMEG_0191|M.smegmatis_MC2_155 -------
MAB_0364c|M.abscessus_ATCC_199 -------
MMAR_1405|M.marinum_M QERAARL
MAV_4602|M.avium_104 -------
TH_4374|M.thermoresistible__bu -------