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PPKPTSPHASEILQNYWEETLEPADLMRRSVEMTKLSGQLIAASEDGQVAAIRLLNHGQGDLADVISTAW TKYFVTVGLVGAQVGQAGAYLSAWANALGAMLAEMSGVVDWTESAITALEASRPAVEAAGQDVDQLIEQI KTEAQSQIAAISSAAMGVLAAVPSWAASIPVSMSIPHSGIQGPCPATTTGTDGTPTGGVTGPGQGAPPGR SAGGVIGPGQVGSAAPLGNAGGVKGPGSGGDPVPGQAGSVTGPGQASTAPAALNSGPAGGVLGPASGTSS SAPKAGGVSGGSVSGSSGASTSASPPVQAHSTATPTSGTPSTTTGHSNSGSGAGTEPSASATPPDAQLIS QSSAAATAPQGLAAARAVAVVSAACGAEVAPVAGSALGPAAASAPLSAAPLSALASAPAAAGAVPAPSPG PPSPPVSPLSPAASGNAVAPPSVAGAQPAAGTGLRATTAAGPAPAPGSVATTHAAAPSSRPVSNWSPHDR DPFSPPAAGVAGDGATGPIISPLTGGCDPLVVPAVLIPPTSSSAALGDQDLATVRSVVEAAGGASQVHWA AGMVVTSGRRQVVLTSDRGRSWVPAEAFLPADVITPWSHEQSSRWGGLLDPARVIVEYAAAAGGRLTALA STFSGAPAVAAGIPWTLVDGTDRAHPELLSGPVVTRFELQVSPERRRAVKHITDPVKQRVQVLWLALSAD ETAGSLGTRGRMLSLFRDHLGRIDRPRWVASLPWEQLEDEHHRLCVQERAARL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1405 | - | - | 100% (754) | hypothetical protein MMAR_1405 |
M. marinum M | MMAR_3066 | - | 8e-26 | 24.28% (626) | hypothetical protein MMAR_3066 |
M. marinum M | MMAR_3550 | - | 3e-17 | 27.03% (370) | PE-PGRS family protein, PE_PGRS39 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3377c | PE_PGRS50a | 1e-17 | 29.31% (331) | hypothetical protein Mb3377c |
M. gilvum PYR-GCK | Mflv_3843 | - | 2e-27 | 31.71% (391) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv2082 | - | 4e-17 | 23.99% (371) | hypothetical protein Rv2082 |
M. leprae Br4923 | MLBr_01828 | PPE | 5e-08 | 28.87% (194) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0112 | - | 7e-16 | 25.00% (424) | hypothetical protein MAB_0112 |
M. avium 104 | MAV_0207 | - | 2e-17 | 29.82% (285) | Erp protein |
M. smegmatis MC2 155 | MSMEG_0071 | - | 6e-15 | 28.71% (310) | hypothetical protein MSMEG_0071 |
M. thermoresistible (build 8) | TH_2084 | - | 1e-07 | 26.57% (271) | Erp protein |
M. ulcerans Agy99 | MUL_2783 | - | 3e-17 | 27.30% (370) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_0085 | - | 1e-26 | 26.11% (720) | hypothetical protein Mvan_0085 |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGGA MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 -MMGLGKLEKPKGGHFDRMVGPGAWPETEESEFSNRQAEILGIRQ----- Mvan_0085|M.vanbaalenii_PYR-1 --MGISKN---VGEYVEEMTEPAGWPHVDEDHLYTRASGFVDKVT----- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M ------MPPKPTSPHASEILQNYWEETLEPADLMRRSVEMTKLSG----- Mflv_3843|M.gilvum_PYR-GCK VLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPGA MAB_0112|M.abscessus_ATCC_1997 -----------MLFAVGRHRANPSRRSQQLKRASARAAVVTVLSSG---- MUL_2783|M.ulcerans_Agy99 ---------------MPHVTTSPNLLAATAGDLAAIASTMR--------- Mb3377c|M.bovis_AF2122/97 --------------MVMSLMVAPELVAAAAADLTGIGQAIS--------- Rv2082|M.tuberculosis_H37Rv MAGDLPPGRWSALLVGAWWPARPDAPMAGVTYWRKAAQLKRNEANDLRNE MLBr_01828|M.leprae_Br4923 ------MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSS----- MSMEG_0071|M.smegmatis_MC2_155 ---RLTGAKESWQTHQSYLDSEATWAGTSARAANARVEQHTKSMVAHEHQ Mvan_0085|M.vanbaalenii_PYR-1 ---QLIAVRDSWQQQQARLFGGGAWSGAAANAAETAIQARVSEMISLINH MAV_0207|M.avium_104 -------------------------------------------------M TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M ---QLIAASEDGQVAAIRLLNHG--QGDLADVISTAWTKYFVTVGLVGAQ Mflv_3843|M.gilvum_PYR-GCK PVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEGTGG MAB_0112|M.abscessus_ATCC_1997 -----TLMGGFGVFAITTPAADAKPGGGSGNDHDHDHGLGGALHKLTGGL MUL_2783|M.ulcerans_Agy99 ----QASAAAAAPTAAVQPAGGDVVSAGIASLFGAHAYNYQVLSAKAAEF Mb3377c|M.bovis_AF2122/97 ----AANAAAAGPTTQVLAAAGDEVSAAIAALFGTHAQEYQALSARVATF Rv2082|M.tuberculosis_H37Rv RSLLAVNQGRTADDLLERYWRGEQRLATIAHQCEVKSDQSEQVADAVNYL MLBr_01828|M.leprae_Br4923 ----VYAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVD MSMEG_0071|M.smegmatis_MC2_155 LEKVEKWCGEAIGLIGTVKEAIIGTVNSAVEAINEAAADADKNETDA--- Mvan_0085|M.vanbaalenii_PYR-1 LEKAIAWYTMTARTIAQTKATINQNLETSYSFIASIRASPELDEVEK--- MAV_0207|M.avium_104 PNRRRRKLSTAMSAVAALAVASPCAYFLVYESTAGNK-APEHHEFKQ--- TH_2084|M.thermoresistible__bu -----------MSTVAALAVASPFAAIAVTELVSSTQPAPQQREFVQ--- MMAR_1405|M.marinum_M VGQAGAYLSAWANALGAMLAEMSGVVDWTESAITALEASRPAVEAAG--- Mflv_3843|M.gilvum_PYR-GCK AVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAGGLG MAB_0112|M.abscessus_ATCC_1997 LGGGGGGNGGPGSGGARNAPSAPSFGKSLHGGSGSEGAAGGNGDSAK--- MUL_2783|M.ulcerans_Agy99 HDRFVEILQTSAQAYGSTEATNASPLEKAIGVFTAPAEGQAGGPGTG--- Mb3377c|M.bovis_AF2122/97 HEQFVRSLTAAGSAYATAEAANASPLQALEQQVLGAINAPTQLWLGR--- Rv2082|M.tuberculosis_H37Rv RDRLTEIAQSGNQQINQILAGKGPIEAKVAAVNAVIEQSNAMADHVG--- MLBr_01828|M.leprae_Br4923 SAVMAAHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGIN--- MSMEG_0071|M.smegmatis_MC2_155 ------------SSKIEKIKDLAYDFNKSIVQWGADTVQGKEDIPSEPPK Mvan_0085|M.vanbaalenii_PYR-1 ------------DGIIQSWVQSQRAVNTVTVLTAAGDVAAFDSWQ--PPP MAV_0207|M.avium_104 ------------AAVMS--------------------------------D TH_2084|M.thermoresistible__bu ------------ASLLT--------------------------------D MMAR_1405|M.marinum_M ------------QDVDQLIEQIKTEAQSQIAAISSAAMGVLAAVPSWAAS Mflv_3843|M.gilvum_PYR-GCK GAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPG MAB_0112|M.abscessus_ATCC_1997 ------------------------------------------------SD MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 --------------------------------------------PLIGDG Rv2082|M.tuberculosis_H37Rv --------ATAMSNIIDATQRVFDETIGGDAHTWLRDHGVSLDTPARPRP MLBr_01828|M.leprae_Br4923 -----------------------------------------------TIP MSMEG_0071|M.smegmatis_MC2_155 LPKDIFKNVEPATGSQDGEIRDGQADVLFMNSSLGGDASDVRASVKPSRP Mvan_0085|M.vanbaalenii_PYR-1 SPQRIPATLSPPESVSAPSGPEPPKQNVGYFGPTRPPAAEPRGGS-AGLS MAV_0207|M.avium_104 LPGELMGALS---------------------------------------- TH_2084|M.thermoresistible__bu LPTELMGALS---------------------------------------- MMAR_1405|M.marinum_M IPVSMSIPHSGIQGPCPATTTGTDGTPTGGVTGPGQGAPPGRSAG----- Mflv_3843|M.gilvum_PYR-GCK VPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVVDEAGVVTP MAB_0112|M.abscessus_ATCC_1997 KDKDKGPGASVPKP------------------------------------ MUL_2783|M.ulcerans_Agy99 -NGAIGGGLHG--------------------------------------- Mb3377c|M.bovis_AF2122/97 VHGAPGTGQPGGAGG----------------------------------- Rv2082|M.tuberculosis_H37Rv VTAEDMTSMTANSPAGSPFG------------------------------ MLBr_01828|M.leprae_Br4923 IARNEIDYVRMWVEAAIAMG------------------------------ MSMEG_0071|M.smegmatis_MC2_155 VDTWEQDNVGLGEDASGVRPTP--------------AIEPPVEQVEPVNS Mvan_0085|M.vanbaalenii_PYR-1 AKAANDAYMAQGPSASADQPVP--------------ISQSSGGGSPGSPG MAV_0207|M.avium_104 --------QGLSQFGINLPPVP--------------ALSG-GATSTPG-- TH_2084|M.thermoresistible__bu --------EGLAQFGINLPPMP--------------SLTGSGASMSPG-- MMAR_1405|M.marinum_M ----GVIGPGQVGSAAPLGNAG--------------GVKGPGSGGDPVPG Mflv_3843|M.gilvum_PYR-GCK PAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAATPPSSG MAB_0112|M.abscessus_ATCC_1997 --------GSAGSTGKTADSAAG--------------SAGSGTGTPGANS MUL_2783|M.ulcerans_Agy99 ---------GAGGFGDVGQPTAN-------------AAPVGPAGATAAAG Mb3377c|M.bovis_AF2122/97 LLWGNGGNGGSGAAGQVGGPGGAAG-----------LFGNGGSGGSGGAG Rv2082|M.tuberculosis_H37Rv -AAPSAPSHSTTTSGPPTAPTPTSPFG-----TAPMVLSSSSTSSGPPTA MLBr_01828|M.leprae_Br4923 ------TYQEVSTVVVDSAPEAIAAP----------QIMASDALEASSDQ MSMEG_0071|M.smegmatis_MC2_155 GLGGEQPDIRPAPPIPQPVLGRPPSAPAPTAGGPSGPGSAISPSAPT--- Mvan_0085|M.vanbaalenii_PYR-1 GLG-------------------SPGSPSSSTSGSSPISTSGGSSSGS--- MAV_0207|M.avium_104 -----------------------LASPGLGSPGLGSPGLGTPGLGTP--- TH_2084|M.thermoresistible__bu -----------------------LTSPGLTSPGLTSPGLTSPGLTSP--- MMAR_1405|M.marinum_M QAG------------SVTGPGQASTAPAALNSGPAG-GVLGPASGTS--- Mflv_3843|M.gilvum_PYR-GCK SVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPTPEI MAB_0112|M.abscessus_ATCC_1997 SAP--------------------GGSNGSSGGGIGGVGTTVGTTLPH--- MUL_2783|M.ulcerans_Agy99 TGG--------------------SPAQATVHSGPAAGNGDAASVGTG--- Mb3377c|M.bovis_AF2122/97 AAGG----------------VGGSGGWLNGNGGAGGAGGTGANGGAG--- Rv2082|M.tuberculosis_H37Rv PTP------------------TSPFGTAPMPPGPPPPGTVSPPLPPS--- MLBr_01828|M.leprae_Br4923 PSP------------------TAPSQSPQVQNWLQWLQKIGYTDFYN--- MSMEG_0071|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK TLNPANSGIDIATPPAPGLPGAPLEATANITTPGTPGVPGAPVNSSIDVA MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 --------------PVSSSGPPTGGGGGTSIAPSSPLSSGSSLGGSGAEQ Mvan_0085|M.vanbaalenii_PYR-1 --------------GASSSGSGSGSGGSSSAAASSSGTS-PTSGGQSATG MAV_0207|M.avium_104 --------------GLTNPGLTSPGATSPGLTSPGLTSPGLTSPGLTSPG TH_2084|M.thermoresistible__bu --------------GLTSPGLTSPGLTNPGLTSPGLTDPALTTPGLTTPG MMAR_1405|M.marinum_M --------------SSAPKAGGVSGGSVSGSSGASTSASPPVQAHSTATP Mflv_3843|M.gilvum_PYR-GCK TPGEVGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVATPPAPGVPGAPV MAB_0112|M.abscessus_ATCC_1997 --------------SGGAAGVHTPTAEGAAATESSAGTGTHTEEHPSLKG MUL_2783|M.ulcerans_Agy99 -----------------VQHGGAGGGSGDGMASSHVSDGGAARAGGAANS Mb3377c|M.bovis_AF2122/97 ---------------GNAWLFGAGGSGGAGTNGGVGGSGGFVYGNGGAGG Rv2082|M.tuberculosis_H37Rv ---------------APAVGVGGPSVPAAGMPPAAAAATAPLSPQSLGQS MLBr_01828|M.leprae_Br4923 ---------------TLVQPLITSLTNHPFFQGMFSGFDPWLPSLGNPLS MSMEG_0071|M.smegmatis_MC2_155 AADASAAALGQNPVGRAPVDPLQQFTQSFSD------------------- Mvan_0085|M.vanbaalenii_PYR-1 AAGGQPTAASPASAAKAQPSPMQQMVNQAPP------------------- MAV_0207|M.avium_104 AAP---TTPGLTAPGALP-------------------------------- TH_2084|M.thermoresistible__bu LTTPGLTTPGLTTPGLDP-------------------------------- MMAR_1405|M.marinum_M TSGTPSTTTGHSNSGSGAGTEPSASATPPDA------------------- Mflv_3843|M.gilvum_PYR-GCK VGEAGVTTPGAPGAPGAPANAAVDVATPPAPGVPGAPVVGEAAVTTPGAP MAB_0112|M.abscessus_ATCC_1997 ALGSVAGALAPKTETATTPKT----------------------------- MUL_2783|M.ulcerans_Agy99 AGGTDAAASSSGAGGGGS-------------------------------- Mb3377c|M.bovis_AF2122/97 IGGIGGIGGNGGDAGLFGNGGAGGPGPRACR------------------- Rv2082|M.tuberculosis_H37Rv FTTGMTTGTPAAAGAQALSAGALHAATEPLP------------------- MLBr_01828|M.leprae_Br4923 FLSPFNIAFALGTPMDIGSYVGYLSQTFAFIG------------------ MSMEG_0071|M.smegmatis_MC2_155 ------------------SAGTPVHAASTGGGSVPPPPLTPPPTVPAGES Mvan_0085|M.vanbaalenii_PYR-1 ------------------PLASSAPATSPAPAPAPSQPAAAP-SAAAGAG MAV_0207|M.avium_104 --------------------TTPGGGVATPGAGLNPALSNPGLTSPAGTA TH_2084|M.thermoresistible__bu --------------------AQTTPGLTTPGVST-PDLTNPALTSPLGEA MMAR_1405|M.marinum_M ------------------QLISQSSAAATAPQGLAAARAVAVVSAACGAE Mflv_3843|M.gilvum_PYR-GCK GVPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPGVPAGGDAG MAB_0112|M.abscessus_ATCC_1997 -------------------ETATSPHTSTAPGATAETPTAGTTHPEHESS MUL_2783|M.ulcerans_Agy99 ----------------------AGQGVASTGGDHGAGATSSASGHSPGHG Mb3377c|M.bovis_AF2122/97 -----------------VPPASTAATAATAATAEPAATAGAAGYWLATAG Rv2082|M.tuberculosis_H37Rv ---------------PPAPPPTTPTVTTPTVATATTAGIPHIPDSAPTPS MLBr_01828|M.leprae_Br4923 -------------------ADLAAAFASGNPVTIGFTLLFTTIEAIGTII MSMEG_0071|M.smegmatis_MC2_155 MGPASAHSTPTSLNSAPAAPVQPPAAGGPMGAASGMPVAPPPLGPPPT-- Mvan_0085|M.vanbaalenii_PYR-1 PSSGGVGGISASAGSAPVGAAPPSGAPPAPPVPLGPPTSPAPPGPVPP-- MAV_0207|M.avium_104 PG-LGSPTV--APSEVPIDSGAGL-DPGAGGTYP-------ILGDPST-- TH_2084|M.thermoresistible__bu PGGLTTPSVGLDPALTPISNTAGLPAPGEVPITA-------PLGPDPT-- MMAR_1405|M.marinum_M VAPVAGSALGPAAASAPLS-AAPLSALASAPAAAGAVPAPSPGPPSPP-- Mflv_3843|M.gilvum_PYR-GCK VVTPPAPGVPGAPAATEAGLATPPGPGAPGAPVVGDAGVATPPGPGVPGA MAB_0112|M.abscessus_ATCC_1997 AEEPKVPGVTVNMGGRTIIIWKKKPSTSTHTPGAGTGTNPGHESEGDR-- MUL_2783|M.ulcerans_Agy99 VGLGSGLGRSLDGYGTAALAGGPLGAVGSGAPGAVGGVGELLAPTATS-- Mb3377c|M.bovis_AF2122/97 PAGPAASAATVVRAALAIRVSPSTTVPAVTAVTAATPAWAGPVGPAACWR Rv2082|M.tuberculosis_H37Rv PAPIAPPTTDNASAMTPIAPMVANGPPASPAPPAAAPAGPLPAYGADLRP MLBr_01828|M.leprae_Br4923 TDTIALVKTMIEQSFVLLPMILPLLTAPLAVATAGAAGSFAGLSELAG-- MSMEG_0071|M.smegmatis_MC2_155 --------------PPPAAPVAAPPPAAAPPPAQPNAAGGGAQVAPIPVS Mvan_0085|M.vanbaalenii_PYR-1 --------------TGTPGTAPGGAMGPGVAPMSTTGTAGGAAPAPIPVS MAV_0207|M.avium_104 --------------FGNASPIGGGGTGLGG-GSSSGGSGG---------- TH_2084|M.thermoresistible__bu --------------LGTYPILGDPSLAMAPPVATSTGGGG---------- MMAR_1405|M.marinum_M --------------VSPLSPAASGNAVAPPSVAGAQPAAGTGLRATTAAG Mflv_3843|M.gilvum_PYR-GCK PIVDEAGLATPPAPVAPVEGAGGAVPPAGPPPAPVFGDAGAPVEAAAGGA MAB_0112|M.abscessus_ATCC_1997 --------------DHVINLPGFPALGGATNPDAPFGGAAG--------- MUL_2783|M.ulcerans_Agy99 ------------------ALPTAASATAEPSLAMS--------------- Mb3377c|M.bovis_AF2122/97 -------VRTVPPAPPPPAAATAAMAASAPPPTHPYKPAGP--------- Rv2082|M.tuberculosis_H37Rv -----------PVTTPPATPPTPTGPISGAAVTPSSPAAGGSLMSPVVN- MLBr_01828|M.leprae_Br4923 --------------LVGVAPPGLPSAPPVAAVAPVVPPSMP--------- MSMEG_0071|M.smegmatis_MC2_155 AARAERDLAQRAVRR---------------------SGVDPMETARRIAA Mvan_0085|M.vanbaalenii_PYR-1 TARAERDAIAAASTAGA--------------LRRKTNGADPLQQARHIAA MAV_0207|M.avium_104 ----------------------------------------LVNDVMQAAN TH_2084|M.thermoresistible__bu ----------------------------------------LISELSTAAN MMAR_1405|M.marinum_M PAPAPGSVATTHAAAP--------------------SSRPVSNWSPHDRD Mflv_3843|M.gilvum_PYR-GCK PVEAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAA MAB_0112|M.abscessus_ATCC_1997 -------------------------------------TRTPGGNPSIHTG MUL_2783|M.ulcerans_Agy99 ----------------------------------------TKAQLVRATN Mb3377c|M.bovis_AF2122/97 ------------------------------------AVMAVMAGWSATAA Rv2082|M.tuberculosis_H37Rv ------------------------------------KSTAPATTQAQPSN MLBr_01828|M.leprae_Br4923 ----------------------------------------TLASIPTPTP MSMEG_0071|M.smegmatis_MC2_155 ALNAPGMTNVEDFKFFWVTGLTADGKIVVANNYGIAYIPQQVHLPEQVHM Mvan_0085|M.vanbaalenii_PYR-1 ALNVG----IMDFGFFWVTGVTMEGTIVVANSYGLAYIPAGVALPDQVRM MAV_0207|M.avium_104 QLGAG----------------------------------QAIDLLKGLVM TH_2084|M.thermoresistible__bu QLGAG----------------------------------QAIDLLKGVVM MMAR_1405|M.marinum_M PFSPPAAGVAGDGATGPIISPLTGGCDPLVVPAVLIPPTSSSAALGDQDL Mflv_3843|M.gilvum_PYR-GCK PAAAGGAAPGGAPGGPVAGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGV MAB_0112|M.abscessus_ATCC_1997 PVAPP-----------------------------------TVPTPKAPAV MUL_2783|M.ulcerans_Agy99 PLQPVN--------------------------------PAHSDSSANQGG Mb3377c|M.bovis_AF2122/97 PAAPAVP--------------------------------VMRVPPALPVP Rv2082|M.tuberculosis_H37Rv PTPPLAS-------------------------------ATAAATTGAAAG MLBr_01828|M.leprae_Br4923 MPAPAAS-------------------------------TAPVVTPPGPPP MSMEG_0071|M.smegmatis_MC2_155 ASADESISP----------------------------------AERARWV Mvan_0085|M.vanbaalenii_PYR-1 ATADESIPA----------------------------------GERAKWA MAV_0207|M.avium_104 PAITQGMHG----------------------------------GAAAGAL TH_2084|M.thermoresistible__bu PAVTSAIKS----------------------------------AAQP--- MMAR_1405|M.marinum_M ATVRSVVEA----------------------------------AGGASQV Mflv_3843|M.gilvum_PYR-GCK PGGAAAVPAGAVTPPAPGVPGAPVFGEAGVVTPPAPGVPGGAAAVPAGVV MAB_0112|M.abscessus_ATCC_1997 AIATPPAPP----------------------------------------- MUL_2783|M.ulcerans_Agy99 PARRTGVER----------------------------------------- Mb3377c|M.bovis_AF2122/97 PYNRRAVTAP---------------------------------------- Rv2082|M.tuberculosis_H37Rv DTSRRAAEQ------------------------------------QRLRR MLBr_01828|M.leprae_Br4923 VTAPPSVTG----------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 NEPIVAVQRWAEHHGKNLRAVIATEDQLKNSDAGVHHEVLRPEDIPEGGK Mvan_0085|M.vanbaalenii_PYR-1 TYPILAVQGWAQHHNQQLRAVVATEEQFANFDPGVAKIILTQDDIPESGQ MAV_0207|M.avium_104 PGAAGALPGAAGAL------------------------------PGAAGA TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M HWAAGMVVTSGRRQVVLTSDRGRSWVPAEAFLPADVITPWSHEQSSRWGG Mflv_3843|M.gilvum_PYR-GCK TPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATPPVPGVPGGGT MAB_0112|M.abscessus_ATCC_1997 -------------------------------------------------V MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv ILDTVARQEPGLSWAAGLRDNGQTTLLVTDLASGWIPPHIRLPAHITLLE MLBr_01828|M.leprae_Br4923 -------------------------------------------------- MSMEG_0071|M.smegmatis_MC2_155 MAGRDRLQVIAPDVSAQLARVSDTD------------------------- Mvan_0085|M.vanbaalenii_PYR-1 MQGRSRLEVIAPEAAQRLSAVSDFG------------------------- MAV_0207|M.avium_104 LPGAAGALPAAAGAAGALPAAAGAA------------------------- TH_2084|M.thermoresistible__bu -PGPDVAPPPAP----EVPAPDA--------------------------- MMAR_1405|M.marinum_M LLDPARVIVEYAAAAGGRLTALAST------------------------- Mflv_3843|M.gilvum_PYR-GCK TVPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGSTDTYINYPAPPVP MAB_0112|M.abscessus_ATCC_1997 LAPLAPVVPPTPPVVTVKQAEGGRG------------------------- MUL_2783|M.ulcerans_Agy99 -DGPTLFLPLTSLRGLRRHSKKRSG------------------------- Mb3377c|M.bovis_AF2122/97 MAAPGATAVMAEMAAPSTATAASAAR------------------------ Rv2082|M.tuberculosis_H37Rv PAPRRRHATVTDLLGTTTVAAAHHPHG----------------------- MLBr_01828|M.leprae_Br4923 -AGVESFGYLVGRLPSTARGVVGTS------------------------- MSMEG_0071|M.smegmatis_MC2_155 -----LVKILPPAPADANPPEDRRKLLWDNVWK--------PLASRSTKR Mvan_0085|M.vanbaalenii_PYR-1 -----LNDLLPPATADLEPPADDSARLWFEVAK--------PLMSTNPQR MAV_0207|M.avium_104 -----PALPPV--------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M -----FSGAPAVAAGIPWTLVDGTDRAHPELLSGPVVTRFELQVSPERRR Mflv_3843|M.gilvum_PYR-GCK PTPPNSTGVSAGTPGSPAPGTPGSTLTLTDLLTPPGIARTLQNTASSVMG MAB_0112|M.abscessus_ATCC_1997 -------GDVVVTAGGTKQPEAVTKPIQQFVAAETIAPRTGYTDYLRLTK MUL_2783|M.ulcerans_Agy99 -----------------------------------------LRAQSGRLR Mb3377c|M.bovis_AF2122/97 --------AVPAVAAAPAETDSTPPPWVRPVPMAVWAATAARAVTAVVAA Rv2082|M.tuberculosis_H37Rv ----YLSQPDPDTPALTGDRTARIAPTIDELGPTLVETVRRHDTLPPIAQ MLBr_01828|M.leprae_Br4923 ---------VRQQSSAPDRIEAPDAAATPQEQARSRWRRRAKVTPFDSSG MSMEG_0071|M.smegmatis_MC2_155 GERHLAAFVAYAAHAQEHALYAAHTAALPDDQRQAIREF----------- Mvan_0085|M.vanbaalenii_PYR-1 SGPHLQAFVAYAKHAQELALHKAHNAAEPGDQRLAIADW----------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M AVKHITDPVKQRVQVLWLALSADETAGSLGTRGRMLSLFRDHLGRIDRPR Mflv_3843|M.gilvum_PYR-GCK ATPPGTPPVPGGSGSVSLAVPGTPSPIAPLAATGLSNLVSPPSLTIPSIP MAB_0112|M.abscessus_ATCC_1997 TSEIAAVAIPGAAGIAMMTFVGAALGYRQAKAG----------------- MUL_2783|M.ulcerans_Agy99 DSGDAVSSPRWEPDDLLRALGLRPPGHQ---------------------- Mb3377c|M.bovis_AF2122/97 PAAPRSPAPPARPGTAAPAVTAARPVMAEPVPPVM--------------- Rv2082|M.tuberculosis_H37Rv AVVVAATRNYGVPDNETDLLHHKTTEIHQAVLTTYPNHDIATVVDWMLLA MLBr_01828|M.leprae_Br4923 SPNPKAAPTASDQGAGTLGLAGTARQASSGPATGLVTLSNGTFSDSPRAP MSMEG_0071|M.smegmatis_MC2_155 ----IYWQHVGQLTADALSPA----------------------------- Mvan_0085|M.vanbaalenii_PYR-1 ----VYWQHLEVLLTDAVSTDAAV-------------------------- MAV_0207|M.avium_104 -------------------------------------------------- TH_2084|M.thermoresistible__bu -------------------------------------------------- MMAR_1405|M.marinum_M WVASLPWEQLEDEHHRLCVQERAARL------------------------ Mflv_3843|M.gilvum_PYR-GCK GLPVPLPNTVPVPSDLLCVGTDWSASQGDSAATPPAAEVPRVVTGAAPTG MAB_0112|M.abscessus_ATCC_1997 -------HTVRASAAARFLE------------------------------ MUL_2783|M.ulcerans_Agy99 -------------------------------------------------- Mb3377c|M.bovis_AF2122/97 -------------------------------------------------- Rv2082|M.tuberculosis_H37Rv AINALIAGDQSGANYHLAWAIAAISTRRSR-------------------- MLBr_01828|M.leprae_Br4923 MLPRTWGADPTFCYNAADIGPAGGWDDE---------------------- MSMEG_0071|M.smegmatis_MC2_155 --------- Mvan_0085|M.vanbaalenii_PYR-1 --------- MAV_0207|M.avium_104 --------- TH_2084|M.thermoresistible__bu --------- MMAR_1405|M.marinum_M --------- Mflv_3843|M.gilvum_PYR-GCK DRRDRWGNR MAB_0112|M.abscessus_ATCC_1997 --------- MUL_2783|M.ulcerans_Agy99 --------- Mb3377c|M.bovis_AF2122/97 --------- Rv2082|M.tuberculosis_H37Rv --------- MLBr_01828|M.leprae_Br4923 ---------