For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTDAEFDLATGEFDVGLVRAGAAAAARRRELDISQRSLAADGIINAGALIAFEKGRSWPRERTRLKLEEV LRWPPGTIARLRQGGSVPTTSAPVAPPPPPEPPAAAPAPVTSVPAADEVPLIAQAVLTAVHTLETTINAM PPESDPDFVPRVTAILGDLRQLEAVASRAARISMVTPPLIKALSAVRRQIDELTMRAANAPGATLGQRLY AARRQANLTVAETAQAAGVSEDAIARTEAEYPVDAAAVHAIEALIDSLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0052 | - | - | 100% (259) | hypothetical protein MSMEG_0052 |
| M. smegmatis MC2 155 | MSMEG_6518 | - | 5e-23 | 47.54% (122) | hypothetical protein MSMEG_6518 |
| M. smegmatis MC2 155 | MSMEG_1634 | - | 3e-14 | 34.65% (127) | forkhead-associated protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3893 | - | 2e-72 | 63.22% (242) | hypothetical protein Mb3893 |
| M. gilvum PYR-GCK | Mflv_0777 | - | 1e-80 | 64.75% (261) | hypothetical protein Mflv_0777 |
| M. tuberculosis H37Rv | Rv3863 | - | 2e-72 | 63.22% (242) | hypothetical protein Rv3863 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1298c | - | 4e-28 | 45.89% (146) | hypothetical protein MAB_1298c |
| M. marinum M | MMAR_5438 | - | 2e-77 | 64.26% (249) | putative regulatory protein |
| M. avium 104 | MAV_0041 | - | 3e-08 | 25.51% (247) | helix-turn-helix domain-containing protein |
| M. thermoresistible (build 8) | TH_2085 | - | 1e-80 | 62.78% (266) | HYPOTHETICAL ALANINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_0041 | - | 3e-07 | 22.69% (238) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0068 | - | 1e-84 | 67.57% (259) | hypothetical protein Mvan_0068 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3893|M.bovis_AF2122/97 --MAGERKVCPPSRLVPANKGSTQMSKAGSTVGPAPLVACSGGTSDVIEP
Rv3863|M.tuberculosis_H37Rv --MAGERKVCPPSRLVPANKGSTQMSKAGSTVGPAPLVACSGGTSDVIEP
MMAR_5438|M.marinum_M MLVSGTRALPPAS--VAASEESTYMPDAESTARPALRVARGGDSPGLVTP
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0041|M.avium_104 --------------------------------------------------
MUL_0041|M.ulcerans_Agy99 --------------------------------------------------
Mb3893|M.bovis_AF2122/97 RRGVAIIGHSCRVGTQIDDSRISQTHLRAVSDDGRWRIVGNIPRGMFVGG
Rv3863|M.tuberculosis_H37Rv RRGVAIIGHSCRVGTQIDDSRISQTHLRAVSDDGRWRIVGNIPRGMFVGG
MMAR_5438|M.marinum_M --GHRPVGRGALTNARLDDPVLSQTHVRAVSDGGQRRIVTNSPNGMFVDG
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0041|M.avium_104 --------------------------------------------------
MUL_0041|M.ulcerans_Agy99 --------------------------------------------------
Mb3893|M.bovis_AF2122/97 RRGSSVTVSDKTLIRFGDPPGGKALTFEVVRPSDSAAQHGRVQPSADLSD
Rv3863|M.tuberculosis_H37Rv RRGSSVTVSDKTLIRFGDPPGGKALTFEVVRPSDSAAQHGRVQPSADLSD
MMAR_5438|M.marinum_M TRKSSVAVSDKTIVRFGDPTGGKALTFEVVRPSNSPEEDSREQRPAEQSD
Mflv_0777|M.gilvum_PYR-GCK ------------------------------------------MTNAEPID
Mvan_0068|M.vanbaalenii_PYR-1 ------------------------------------------MTNAEPVD
TH_2085|M.thermoresistible__bu ------------------------------------------MTDVDLTA
MSMEG_0052|M.smegmatis_MC2_155 ------------------------------------------MTDAE-FD
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0041|M.avium_104 --------------------------------------------------
MUL_0041|M.ulcerans_Agy99 --------------------------------------------------
Mb3893|M.bovis_AF2122/97 DPAHNAAPVAPDPGVVRAGAAAAARRRELDISQRSLAADGIINAGALIAF
Rv3863|M.tuberculosis_H37Rv DPAHNAAPVAPDPGVVRAGAAAAARRRELDISQRSLAADGIINAGALIAF
MMAR_5438|M.marinum_M SQTN-----EADPGVVRAGAAAAARRRELDISQRSLAADGIINAGALIAF
Mflv_0777|M.gilvum_PYR-GCK ESIG-----APDPGMARAGAAAAARRRELNISQRSLAAGGIINAGALIAF
Mvan_0068|M.vanbaalenii_PYR-1 QSTG-----APDPGMVRAGAAAAARRRELDISQRSLAAEGIINAGALIAF
TH_2085|M.thermoresistible__bu SPVS-----EVDPGLARAGAAAAARRRELNISQRRLAAEGIINAGALIAF
MSMEG_0052|M.smegmatis_MC2_155 LATG-----EFDVGLVRAGAAAAARRRELDISQRSLAADGIINAGALIAF
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0041|M.avium_104 ------------MSRESAGAAIRALRESRDWSLADLAAATGVSIMGLSYL
MUL_0041|M.ulcerans_Agy99 ------------MSRESAGAAIRALRESHDWSLADLAAATGVSIMGLSYL
Mb3893|M.bovis_AF2122/97 EKGRSWPRERTRAKLEEVLQWPAGTIARIRRGEPTEPATNP---------
Rv3863|M.tuberculosis_H37Rv EKGRSWPRERTRAKLEEVLQWPAGTIARIRRGEPTEPATNP---------
MMAR_5438|M.marinum_M EKGRSWPRERTRAKLEEVLQWPAGTIARIRQGESVAPEPAP---------
Mflv_0777|M.gilvum_PYR-GCK EKGRSWPRERTRARLEEILQWPPGTIAALRRGEPVHPAPTP---------
Mvan_0068|M.vanbaalenii_PYR-1 EKGRSWPRERTRARLEEILQWPPGTIARLRRGEPLRAAPPPP--------
TH_2085|M.thermoresistible__bu EKGRSWPRERTRAKLEQVLRWPPGTIARLRAGEDVGPAGGPATGAQEPSA
MSMEG_0052|M.smegmatis_MC2_155 EKGRSWPRERTRLKLEEVLRWPPGTIARLRQGGSVPTTSAPVAPPPPP--
MAB_1298c|M.abscessus_ATCC_199 -----------------------------------MPEVVP---------
MAV_0041|M.avium_104 ERGARKPHKSTVQKIENGLGLPPGTYSRLLVAADPEAELARLMAAQP---
MUL_0041|M.ulcerans_Agy99 ERGARKPHKGTVQKVENGLGLPPGTYSRMLVAADPEAELARLLAARP---
.
Mb3893|M.bovis_AF2122/97 ------DASPGLRPA------DGPASLIAQAVTAAVDGCSLAIAALPATE
Rv3863|M.tuberculosis_H37Rv ------DASPGLRPA------DGPASLIAQAVTAAVDGCSLAIAALPATE
MMAR_5438|M.marinum_M ------EASVEAPTS------DGPASLIAQAVAAAVDTCSLAIAALPAPE
Mflv_0777|M.gilvum_PYR-GCK ------EARPPASG--------DEVSLIAQAVITAVHAFGSTISSLPPAD
Mvan_0068|M.vanbaalenii_PYR-1 ------ESRAPASN--------DEVSLIAQAVTTAVSAFGSTVAALPPVD
TH_2085|M.thermoresistible__bu TRTDQADYRPNAPGSDHGG-SDDEVPLVAQAVLAAVNTLDDASEALPDVD
MSMEG_0052|M.smegmatis_MC2_155 ------EPPAAAPAPVTSVPAADEVPLIAQAVLTAVHTLETTINAMPPES
MAB_1298c|M.abscessus_ATCC_199 ----D----------------DGEAPVIVSLVDAAVHMYSSAIDTLPDPS
MAV_0041|M.avium_104 -----VAEMPARRTGPVVVDRHSDTEVLEGYAEAQLDALKSVIDRLPATT
MUL_0041|M.ulcerans_Agy99 -----TETASPRRRGVVVVDRHSDTDVLEGYAEAQLDALRSVIDRLPAST
. . :: . : : . :*
Mb3893|M.bovis_AF2122/97 DPEFTERAAPILADLRQLEAIAVQATRISR-ITPELIKALGAVRRHHDEL
Rv3863|M.tuberculosis_H37Rv DPEFTERAAPILADLRQLEAIAVQATRISR-ITPELIKALGAVRRHHDEL
MMAR_5438|M.marinum_M EPDFTERAAPILADLRQLEGIAVQATRISR-ITPELIKALGAVRRYHDKL
Mflv_0777|M.gilvum_PYR-GCK DAAFIPRVTAILADLRQLEAVAARAARIGR-VTPALIKALSTVRGLYDDL
Mvan_0068|M.vanbaalenii_PYR-1 DAAFVPRVTAILADLRQLDAVASRAARIGR-VTPALIKALSAVRGLYDDL
TH_2085|M.thermoresistible__bu HPEFTPRLTKILADLRQLEAVAARAARISR-VSPRVIKALSAVRRSIDEL
MSMEG_0052|M.smegmatis_MC2_155 DPDFVPRVTAILGDLRQLEAVASRAARISM-VTPPLIKALSAVRRQIDEL
MAB_1298c|M.abscessus_ATCC_199 DPEYGERVAVVLSGLRKLESAISKAAGRSR-VTPSVIVALSGVRHRYDDL
MAV_0041|M.avium_104 SNEYETYILSVIAQCVKAELLAASSWRVAVNAGADSTGRLMEHLQALEAT
MUL_0041|M.ulcerans_Agy99 SNEYDTYILSVVAQCVKAEMLAASSWRVAVNAGSESSARLMEHLQALEAT
: ::. : : : . . * :
Mb3893|M.bovis_AF2122/97 MRLGATAPGATLAQRLYAARRRANLSTLETAQAAGVAEEMIVGAEAEEEL
Rv3863|M.tuberculosis_H37Rv MRLGATAPGATLAQRLYAARRRANLSTLETAQAAGVAEEMIVGAEAEEEL
MMAR_5438|M.marinum_M MTLSATAPGATLAQRLYAARRRANLSTSETAQAAGVTEELIVRAEAEEAL
Mflv_0777|M.gilvum_PYR-GCK MLRAAGAPQAGLGHRLYAARRGANLTVLETAQAAGVSERAIEQAEAGEPV
Mvan_0068|M.vanbaalenii_PYR-1 MVRAARAPHATLGQRLYAARRGANLTVLETAQAAGVSEDAVQQAEADEPL
TH_2085|M.thermoresistible__bu TLRGARAPQATLGQRLYAARRGANLTIEETAQAAGVPAEVIIAAEADEPV
MSMEG_0052|M.smegmatis_MC2_155 TMRAANAPGATLGQRLYAARRQANLTVAETAQAAGVSEDAIARTEAEYPV
MAB_1298c|M.abscessus_ATCC_199 MKAAANSPSATLGQRLYTARRRARLTAQETANGAGLKVGFLTAIESEEPV
MAV_0041|M.avium_104 RVALLKRMPTSLSARFDRACAQSSLPETIIAALVGVDVDEMWDIRNRGVI
MUL_0041|M.ulcerans_Agy99 RTALLERMPASLSARFDRACALSQLPDAVIAALIGVDSDELWDIRNRGVI
: *. *: * : *. * *: : . :
Mb3893|M.bovis_AF2122/97 PAEATEAIEALIRQIN-----------------
Rv3863|M.tuberculosis_H37Rv PAEATEAIEALIRQIN-----------------
MMAR_5438|M.marinum_M HAEAAEAIEALIRQIN-----------------
Mflv_0777|M.gilvum_PYR-GCK TASEADAIETLVGQIA-----------------
Mvan_0068|M.vanbaalenii_PYR-1 SPADIAAIETLISQIG-----------------
TH_2085|M.thermoresistible__bu AATAAGAIETLIAELDQP---------------
MSMEG_0052|M.smegmatis_MC2_155 DAAAVHAIEALIDSLR-----------------
MAB_1298c|M.abscessus_ATCC_199 TEDEAAKIKDLIAALGG----------------
MAV_0041|M.avium_104 SPSALPRVRAFTDAVESASRDEASQGDDEEGS-
MUL_0041|M.ulcerans_Agy99 PPGALPRIRAFVDGSTESSEQQGPGYDDGEGQR
:. :