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MLVSGTRALPPASVAASEESTYMPDAESTARPALRVARGGDSPGLVTPGHRPVGRGALTNARLDDPVLSQ THVRAVSDGGQRRIVTNSPNGMFVDGTRKSSVAVSDKTIVRFGDPTGGKALTFEVVRPSNSPEEDSREQR PAEQSDSQTNEADPGVVRAGAAAAARRRELDISQRSLAADGIINAGALIAFEKGRSWPRERTRAKLEEVL QWPAGTIARIRQGESVAPEPAPEASVEAPTSDGPASLIAQAVAAAVDTCSLAIAALPAPEEPDFTERAAP ILADLRQLEGIAVQATRISRITPELIKALGAVRRYHDKLMTLSATAPGATLAQRLYAARRRANLSTSETA QAAGVTEELIVRAEAEEALHAEAAEAIEALIRQIN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5438 | - | - | 100% (385) | putative regulatory protein |
| M. marinum M | MMAR_3628 | - | 9e-06 | 38.37% (86) | transmembrane ATP-binding protein ABC transporter |
| M. marinum M | MMAR_1174 | - | 9e-06 | 29.20% (137) | transmembrane ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3893 | - | 1e-141 | 70.92% (392) | hypothetical protein Mb3893 |
| M. gilvum PYR-GCK | Mflv_0777 | - | 4e-73 | 61.73% (243) | hypothetical protein Mflv_0777 |
| M. tuberculosis H37Rv | Rv3863 | - | 1e-141 | 70.92% (392) | hypothetical protein Rv3863 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1298c | - | 8e-26 | 44.14% (145) | hypothetical protein MAB_1298c |
| M. avium 104 | MAV_3010 | - | 2e-05 | 35.00% (80) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_0052 | - | 3e-77 | 64.26% (249) | hypothetical protein MSMEG_0052 |
| M. thermoresistible (build 8) | TH_2085 | - | 5e-74 | 58.69% (259) | HYPOTHETICAL ALANINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_1237 | - | 1e-05 | 37.97% (79) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0068 | - | 2e-76 | 63.37% (243) | hypothetical protein Mvan_0068 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3893|M.bovis_AF2122/97 --------------------------------------------------
Rv3863|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5438|M.marinum_M --------------------------------------------------
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 MRYDGAERTFAAGNDVVIGR----DLRADLRVAHPLISR--THLIVRYEQ
MUL_1237|M.ulcerans_Agy99 MWLGSMRYVFAPGRDALVGYGNKFDIRLDGPAPFDTFDRPTPELALRFAG
Mb3893|M.bovis_AF2122/97 --------------------------------------------------
Rv3863|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5438|M.marinum_M --------------------------------------------------
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 GRWVAIDNGSLNGLYVNNRRVPMVDINDGTRVNMGNPD-GPALSFEVGRH
MUL_1237|M.ulcerans_Agy99 NRWVAIDQ-SRNGMFVDGARLATVDIRDGLTITVGDPHHGTPLRFQVTAA
Mb3893|M.bovis_AF2122/97 -----------------------MAGERKVCPPSRLVPANKGSTQMSKAG
Rv3863|M.tuberculosis_H37Rv -----------------------MAGERKVCPPSRLVPANKGSTQMSKAG
MMAR_5438|M.marinum_M ---------------------MLVSGTRALPPAS--VAASEESTYMPDAE
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 QGSAGRPPLTTSIPIVSTPSGPMTGAAQGQPPGTQRISQPQQPASSSFRQ
MUL_1237|M.ulcerans_Agy99 AGARSLPADPP-----RGPGHPAPRPARAEPAPPQPVPPSKPTESVTQQL
Mb3893|M.bovis_AF2122/97 STVGPAPLVACSGGTSDVIEPRRGVAIIGHSCRVGTQIDDSRISQTHLRA
Rv3863|M.tuberculosis_H37Rv STVGPAPLVACSGGTSDVIEPRRGVAIIGHSCRVGTQIDDSRISQTHLRA
MMAR_5438|M.marinum_M STARPALRVARGGDSPGLVTP--GHRPVGRGALTNARLDDPVLSQTHVRA
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 PVQSPTGAQPSHPPSGPTRYPSSGLQHAPQIYRAPSGHAAPPTTAQPAPA
MUL_1237|M.ulcerans_Agy99 PTASATQRIATPPPA-----PSTFERATRPIRLAPLGAPAAPPPMPPHPP
Mb3893|M.bovis_AF2122/97 VSDDGRWRIVGNIPRGMFVGGRRGSSVTVSDKTLIRFGDPPGGKALTFEV
Rv3863|M.tuberculosis_H37Rv VSDDGRWRIVGNIPRGMFVGGRRGSSVTVSDKTLIRFGDPPGGKALTFEV
MMAR_5438|M.marinum_M VSDGGQRRIVTNSPNGMFVDGTRKSSVAVSDKTIVRFGDPTGGKALTFEV
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 QTGRIGGDSSNLATSMMKILRPGRAGLESTPGAVKIGRANDNDIVIPEVL
MUL_1237|M.ulcerans_Agy99 APPSPPRPPSQSSPTPPTPELPAASAPAASEGEEQP---KSRGLVERMID
Mb3893|M.bovis_AF2122/97 VRPSDSAAQHGRVQPSADLSDDPAHNAAP---------------------
Rv3863|M.tuberculosis_H37Rv VRPSDSAAQHGRVQPSADLSDDPAHNAAP---------------------
MMAR_5438|M.marinum_M VRPSNSPEEDSREQRPAEQSDSQTN-------------------------
Mflv_0777|M.gilvum_PYR-GCK -------------MTNAEPIDESIG-------------------------
Mvan_0068|M.vanbaalenii_PYR-1 -------------MTNAEPVDQSTG-------------------------
TH_2085|M.thermoresistible__bu -------------MTDVDLTASPVS-------------------------
MSMEG_0052|M.smegmatis_MC2_155 -------------MTDAE-FDLATG-------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 ASRHHATLIPTPAGTEIHDNRSINGTFVNGVRVDSAVLRDGDVVTIGNID
MUL_1237|M.ulcerans_Agy99 ATRKLLPDRAETDSASASDSDSDSGSSTG----------TGELPSTNRLP
Mb3893|M.bovis_AF2122/97 --------------------------------------------------
Rv3863|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5438|M.marinum_M --------------------------------------------------
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 LVFHGGTLARRDQTAAATRTGGLDVRGVTWTIENNKTLLDNISLTALPGT
MUL_1237|M.ulcerans_Agy99 LKPGARTIG-----VAAYQLG--------LTVDG-HELISDVSFTTRPGS
Mb3893|M.bovis_AF2122/97 VAPDPGVVRAG---------------------------AAAAARRRELDI
Rv3863|M.tuberculosis_H37Rv VAPDPGVVRAG---------------------------AAAAARRRELDI
MMAR_5438|M.marinum_M -EADPGVVRAG---------------------------AAAAARRRELDI
Mflv_0777|M.gilvum_PYR-GCK -APDPGMARAG---------------------------AAAAARRRELNI
Mvan_0068|M.vanbaalenii_PYR-1 -APDPGMVRAG---------------------------AAAAARRRELDI
TH_2085|M.thermoresistible__bu -EVDPGLARAG---------------------------AAAAARRRELNI
MSMEG_0052|M.smegmatis_MC2_155 -EFDVGLVRAG---------------------------AAAAARRRELDI
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 LTAIIGPSGAGKSTFARLVAGYTHPTTGTVAFEGHNVHAEYASLRSRIGM
MUL_1237|M.ulcerans_Agy99 LIAVVGPSRARNSSLAGLLARTRPLSDGVLTVDGHDVAAEPESMRSRIGV
Mb3893|M.bovis_AF2122/97 SQRSLAADGIINAGALIAFEKGRSWPRERTRAKLEEVLQWPAGTIARIRR
Rv3863|M.tuberculosis_H37Rv SQRSLAADGIINAGALIAFEKGRSWPRERTRAKLEEVLQWPAGTIARIRR
MMAR_5438|M.marinum_M SQRSLAADGIINAGALIAFEKGRSWPRERTRAKLEEVLQWPAGTIARIRQ
Mflv_0777|M.gilvum_PYR-GCK SQRSLAAGGIINAGALIAFEKGRSWPRERTRARLEEILQWPPGTIAALRR
Mvan_0068|M.vanbaalenii_PYR-1 SQRSLAAEGIINAGALIAFEKGRSWPRERTRARLEEILQWPPGTIARLRR
TH_2085|M.thermoresistible__bu SQRRLAAEGIINAGALIAFEKGRSWPRERTRAKLEQVLRWPPGTIARLRA
MSMEG_0052|M.smegmatis_MC2_155 SQRSLAADGIINAGALIAFEKGRSWPRERTRLKLEEVLRWPPGTIARLRQ
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 VPQDDVVHGQLTVQQALMYAAELRLPPDTTKEDRAQVVARVLEELEMTQH
MUL_1237|M.ulcerans_Agy99 VTRDNRVHPRLTVEQALSYAARMRLPPDTSADNRRRVVNQVLDEVELTAQ
Mb3893|M.bovis_AF2122/97 GEPTEPATNP---------------DASPGLRPA----------------
Rv3863|M.tuberculosis_H37Rv GEPTEPATNP---------------DASPGLRPA----------------
MMAR_5438|M.marinum_M GESVAPEPAP---------------EASVEAPTS----------------
Mflv_0777|M.gilvum_PYR-GCK GEPVHPAPTP---------------EARPPASG-----------------
Mvan_0068|M.vanbaalenii_PYR-1 GEPLRAAPPPP--------------ESRAPASN-----------------
TH_2085|M.thermoresistible__bu GEDVGPAGGPATGAQEPSATRTDQADYRPNAPGSDHGG------------
MSMEG_0052|M.smegmatis_MC2_155 GGSVPTTSAPVAPPPPP--------EPPAAAPAPVTSVP-----------
MAB_1298c|M.abscessus_ATCC_199 ----MPEVVP-------------D--------------------------
MAV_3010|M.avium_104 LHTRVDKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTML
MUL_1237|M.ulcerans_Agy99 RATRVAKLTPDERRCAAMAIELITRPSLLVVDEPSAGLNPAQEMHVLAML
Mb3893|M.bovis_AF2122/97 -----DGPASLIAQAVTAAVDGCSLAIAALP---------------ATED
Rv3863|M.tuberculosis_H37Rv -----DGPASLIAQAVTAAVDGCSLAIAALP---------------ATED
MMAR_5438|M.marinum_M -----DGPASLIAQAVAAAVDTCSLAIAALP---------------APEE
Mflv_0777|M.gilvum_PYR-GCK ------DEVSLIAQAVITAVHAFGSTISSLP---------------PADD
Mvan_0068|M.vanbaalenii_PYR-1 ------DEVSLIAQAVTTAVSAFGSTVAALP---------------PVDD
TH_2085|M.thermoresistible__bu ----SDDEVPLVAQAVLAAVNTLDDASEALP---------------DVDH
MSMEG_0052|M.smegmatis_MC2_155 ----AADEVPLIAQAVLTAVHTLETTINAMP---------------PESD
MAB_1298c|M.abscessus_ATCC_199 -----DGEAPVIVSLVDAAVHMYSSAIDTLP---------------DPSD
MAV_3010|M.avium_104 RQLADAGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFCGPPGQIGPAMGT
MUL_1237|M.ulcerans_Agy99 RRQADLGCVVVVASMPLAHLNMCDQVLLLTPAGTLAFAGPPVQIESTMGT
. . ::. : : . *
Mb3893|M.bovis_AF2122/97 PEFTERAAPILADLR-----------------------------------
Rv3863|M.tuberculosis_H37Rv PEFTERAAPILADLR-----------------------------------
MMAR_5438|M.marinum_M PDFTERAAPILADLR-----------------------------------
Mflv_0777|M.gilvum_PYR-GCK AAFIPRVTAILADLR-----------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 AAFVPRVTAILADLR-----------------------------------
TH_2085|M.thermoresistible__bu PEFTPRLTKILADLR-----------------------------------
MSMEG_0052|M.smegmatis_MC2_155 PDFVPRVTAILGDLR-----------------------------------
MAB_1298c|M.abscessus_ATCC_199 PEYGERVAVVLSGLR-----------------------------------
MAV_3010|M.avium_104 TNWADIFSTVAGDPDGSRARYLARTGPQPPPPPAEQPAELGDPAHTSLVR
MUL_1237|M.ulcerans_Agy99 ASWPDIFARVSADPQAAHQSFQNRLRASVSPTPPSVLEPERRPAELTFGA
. : : : ..
Mb3893|M.bovis_AF2122/97 QLEAIAVQATRISRITPELIKALGAVRRHHDELMRLGATAP---------
Rv3863|M.tuberculosis_H37Rv QLEAIAVQATRISRITPELIKALGAVRRHHDELMRLGATAP---------
MMAR_5438|M.marinum_M QLEGIAVQATRISRITPELIKALGAVRRYHDKLMTLSATAP---------
Mflv_0777|M.gilvum_PYR-GCK QLEAVAARAARIGRVTPALIKALSTVRGLYDDLMLRAAGAP---------
Mvan_0068|M.vanbaalenii_PYR-1 QLDAVASRAARIGRVTPALIKALSAVRGLYDDLMVRAARAP---------
TH_2085|M.thermoresistible__bu QLEAVAARAARISRVSPRVIKALSAVRRSIDELTLRGARAP---------
MSMEG_0052|M.smegmatis_MC2_155 QLEAVASRAARISMVTPPLIKALSAVRRQIDELTMRAANAP---------
MAB_1298c|M.abscessus_ATCC_199 KLESAISKAAGRSRVTPSVIVALSGVRHRYDDLMKAAANSP---------
MAV_3010|M.avium_104 QFSTIARRQMRLIVSDRGYFVFLALLPFIMGSLSMSVPGDVGFGIPNPMG
MUL_1237|M.ulcerans_Agy99 QVRLILRRQVRVFLASRLYFVFLTLLPFALDALTLLIPGDAGLDRPPPGS
:. : : * : . * .
Mb3893|M.bovis_AF2122/97 ----------------GATLAQRLYAARRRANLSTLETAQAAGVAEEMIV
Rv3863|M.tuberculosis_H37Rv ----------------GATLAQRLYAARRRANLSTLETAQAAGVAEEMIV
MMAR_5438|M.marinum_M ----------------GATLAQRLYAARRRANLSTSETAQAAGVTEELIV
Mflv_0777|M.gilvum_PYR-GCK ----------------QAGLGHRLYAARRGANLTVLETAQAAGVSERAIE
Mvan_0068|M.vanbaalenii_PYR-1 ----------------HATLGQRLYAARRGANLTVLETAQAAGVSEDAVQ
TH_2085|M.thermoresistible__bu ----------------QATLGQRLYAARRGANLTIEETAQAAGVPAEVII
MSMEG_0052|M.smegmatis_MC2_155 ----------------GATLGQRLYAARRQANLTVAETAQAAGVSEDAIA
MAB_1298c|M.abscessus_ATCC_199 ----------------SATLGQRLYTARRRARLTAQETANGAGLKVGFLT
MAV_3010|M.avium_104 AAPNEPGQILVLLNVGAVFMGTALTIRDLIGERAIFLREQAVGLSTSAYL
MUL_1237|M.ulcerans_Agy99 GNPHEAVEILAALNFAAVLMGTALTVRDLVSERQIFRREQAVGLSASTYL
. :. * .. :..*:
Mb3893|M.bovis_AF2122/97 GAEAEEE-LPAEATEAIEALIRQIN-------------------------
Rv3863|M.tuberculosis_H37Rv GAEAEEE-LPAEATEAIEALIRQIN-------------------------
MMAR_5438|M.marinum_M RAEAEEA-LHAEAAEAIEALIRQIN-------------------------
Mflv_0777|M.gilvum_PYR-GCK QAEAGEP-VTASEADAIETLVGQIA-------------------------
Mvan_0068|M.vanbaalenii_PYR-1 QAEADEP-LSPADIAAIETLISQIG-------------------------
TH_2085|M.thermoresistible__bu AAEADEP-VAATAAGAIETLIAELDQP-----------------------
MSMEG_0052|M.smegmatis_MC2_155 RTEAEYP-VDAAAVHAIEALIDSLR-------------------------
MAB_1298c|M.abscessus_ATCC_199 AIESEEP-VTEDEAAKIKDLIAALGG------------------------
MAV_3010|M.avium_104 LAKVCVYTVFAIVQSAIVTTIAVLGKGAPTQGAVALGKPALELFADVALT
MUL_1237|M.ulcerans_Agy99 IGKIIMFGLVAAVQAAILTAIVLLIKGQPVHGTALLPNPGVEIYASVAAT
: : * : :
Mb3893|M.bovis_AF2122/97 --------------------------------------------------
Rv3863|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5438|M.marinum_M --------------------------------------------------
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 CVASAMLGLALSAVAKSNEQIMPLLVVAVMSQLVFSGGMIPVTGRVGLDQ
MUL_1237|M.ulcerans_Agy99 TIVSAIIGLTLSTLGSSLREVLPLVVPVILASLLFAGGLVPLVGTWGFDQ
Mb3893|M.bovis_AF2122/97 --------------------------------------------------
Rv3863|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5438|M.marinum_M --------------------------------------------------
Mflv_0777|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2085|M.thermoresistible__bu --------------------------------------------------
MSMEG_0052|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1298c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3010|M.avium_104 MAWATPARWGFAASASTADLTKLVPGPLTPKDSHWRHAPGTWWFDVGMLI
MUL_1237|M.ulcerans_Agy99 IAWFVPAHWGFAATASTVNLHRVD--VLATHNEVWAHYAGWWAFDIGMLV
Mb3893|M.bovis_AF2122/97 ------------------------------
Rv3863|M.tuberculosis_H37Rv ------------------------------
MMAR_5438|M.marinum_M ------------------------------
Mflv_0777|M.gilvum_PYR-GCK ------------------------------
Mvan_0068|M.vanbaalenii_PYR-1 ------------------------------
TH_2085|M.thermoresistible__bu ------------------------------
MSMEG_0052|M.smegmatis_MC2_155 ------------------------------
MAB_1298c|M.abscessus_ATCC_199 ------------------------------
MAV_3010|M.avium_104 LISTVYLGFVRWKIRLKGG-----------
MUL_1237|M.ulcerans_Agy99 TFGVVAAGLARYRLRPPGVPADHGIAHSRS