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MQDLSQRVLDELNAAQANPPAAEEELTDSFLSKHRGSVVCLGTDGILGGLLAWLGHEFPDQGDRLDSSGS MFDGVIAQIAALGPDGGWQGSAARAYGARNLAQSQHTGLMADLDRLAAELVSAQADDVHKVRSTLWALVA IVSVLLVVCIGLELQGPEGQLVSFYSALPICGTALFVAAVALTFLAVTTSRNASAVQAATQRLTAMVAAL TTGPDAVPGSPEMPTPPKYCLSEFDLAEDTGPTPPQLPDLGSAFTDLPGAPEFHLATGTGAGLPDFGAPQ LPIPALTGLPTLPGPTNLTDLTSVLAGLPTIAQLSTTLSQLTNLAGPTSTTTQPAQQHTTPADHPTQDDA TDTPDTAAAATTTSGERAPLGSTTRPTQQNQDLVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5429 | - | - | 100% (385) | hypothetical protein MMAR_5429 |
| M. marinum M | MMAR_5431 | - | e-141 | 70.54% (370) | hypothetical protein MMAR_5431 |
| M. marinum M | MMAR_5427 | - | e-129 | 71.47% (347) | hypothetical protein MMAR_5427 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 5e-34 | 29.01% (424) | hypothetical protein Mb3894 |
| M. gilvum PYR-GCK | Mflv_0157 | - | 3e-09 | 26.83% (164) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3864 | - | 3e-33 | 29.90% (408) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 2e-11 | 28.99% (169) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1188 | - | 4e-09 | 28.57% (231) | hypothetical protein MSMEG_1188 |
| M. thermoresistible (build 8) | TH_2666 | - | 5e-08 | 24.18% (153) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_5045 | - | 6e-60 | 55.07% (227) | hypothetical protein MUL_5045 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 1e-08 | 27.42% (124) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5429|M.marinum_M --------------------------------------------------
MUL_5045|M.ulcerans_Agy99 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1188|M.smegmatis_MC2_155 MDVVLGVAVTGRVARLAMIGAPANGGQLLDQYALDLSDDGLAELAETIIG
Mflv_0157|M.gilvum_PYR-GCK -----------------------------MALGKLWVDAN-YFYGVADHA
TH_2666|M.thermoresistible__bu -------------------------------MLDAYSTLN-WGKSVVEHP
MMAR_5429|M.marinum_M ---------------------------MQDLSQRVLDELN-AAQANPP--
MUL_5045|M.ulcerans_Agy99 -----------------------MHPDEAATHNRSFEDLL-AYLEPDAGL
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 ------------------MGLFDFYSDLMQHVGESMQRVDPFGPMGAAGE
MSMEG_1188|M.smegmatis_MC2_155 TYQAVTESGNQVAATRLCLPDPAEADTLRMTVANAGVPNVDVVAEAEAAA
Mflv_0157|M.gilvum_PYR-GCK NMMSSDPALGSAAIATDAAILMQSLAAVGGSTMGATGLATSVATPIINAG
TH_2666|M.thermoresistible__bu MSAKDHTGWGIAGTGADFVTLMQGMTEAG-SGLDQGRLAKAAATPIIRAA
MMAR_5429|M.marinum_M ---------------------------AAEEELTDSFLSKHRGSVVCLGT
MUL_5045|M.ulcerans_Agy99 FEPDGFESDAWETQFDGFESDVGEIEREAEAGAADNPHELCPGTVVCGAT
Mb3894|M.bovis_AF2122/97 ---------------------------------------MASGSGLCKTT
Rv3864|M.tuberculosis_H37Rv ---------------------------------------MASGSGLCKTT
MLBr_00405|M.leprae_Br4923 ----------------------------------------MSGAFIIDPT
Mvan_0656|M.vanbaalenii_PYR-1 AVTSLFAVGNIVGDHGTDAMWNLAGDAGDVASVAQSMLPFAKQTLIIEGG
MSMEG_1188|M.smegmatis_MC2_155 ALARSAGADAALLVADDDTASLTVIGEAPEGPSTSTLASVPIGTAGVAAA
:
Mflv_0157|M.gilvum_PYR-GCK LMTLTAASNTLG-FGRPEDGERFTDGARQFSEANDELQQAVPPPDWQGDA
TH_2666|M.thermoresistible__bu LLAMMVMSNTCG-VGTPEKGDRFEEGAQAFEAAGEALGATKSPESWQGKA
MMAR_5429|M.marinum_M DGILGGLLAWLG-HEFPDQGDRLDSSGSMFDGVIAQIAALGPDGGWQGSA
MUL_5045|M.ulcerans_Agy99 LTILGVMWGWLG-DESPEQGDRLASSGSLFDDVGAQVAALGPDGGWRGNA
Mb3894|M.bovis_AF2122/97 SNFIWGQLLLLG-EGIPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQA
Rv3864|M.tuberculosis_H37Rv SNFIWGQLLLLG-EGIPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQA
MLBr_00405|M.leprae_Br4923 LKAIEAWHALLG-IGVPNDGGVLYSSLSFFEKALEHLAAAFPGDGWLGSA
Mvan_0656|M.vanbaalenii_PYR-1 LKMISVMEEQSGGANVPSEGESYSDSAHRFNQVGDTLASAMPDDRWRGTA
MSMEG_1188|M.smegmatis_MC2_155 CATVLQQAAGEAPTRVMLVGQRLDLDSVAAELRSMAPVEVPPDAGFAIAR
: . * . . . :
Mflv_0157|M.gilvum_PYR-GCK SDAYGLRNTEQQQRAGSMATFDGQIQEVLAEEAGQVQDTRDFVSTRQVML
TH_2666|M.thermoresistible__bu SNTYTDRNDEQRARAERMAAIDRTVKEILDAEAHQVDVARKMLDRCQTVL
MMAR_5429|M.marinum_M ARAYGARNLAQSQHTGLMADLDRLAAELVSAQADDVHKVRSTLWALVAIV
MUL_5045|M.ulcerans_Agy99 AQAYWVQNLAQSRHATLMADLDRLTAGLVSSQADAVKQARERLSVLIAVV
Mb3894|M.bovis_AF2122/97 AEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMI
Rv3864|M.tuberculosis_H37Rv AEAYLNQNIAQQLRAQVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMI
MLBr_00405|M.leprae_Br4923 ADKYAGQNRKRVDIFQELAELDKELIELIHNQANSVQTTRGILDGAKKAL
Mvan_0656|M.vanbaalenii_PYR-1 ADAYTLANEQQYARAGKLADADLKVRMALSAEAGEVRTARRMFNQAATVL
MSMEG_1188|M.smegmatis_MC2_155 GAAQSAEGFAPAGAATQMAPALDATQMAPAATDATQLAPSVDATQLAPAA
. . :.
Mflv_0157|M.gilvum_PYR-GCK AAAIPAAITAKLIPPGGAAAAMAIELA-----------------------
TH_2666|M.thermoresistible__bu SLSIPAAIAAKAIPFKGPAISTAIEVA-----------------------
MMAR_5429|M.marinum_M SVLLVVCIGLELQGPEGQLVSFYSALP-----------------------
MUL_5045|M.ulcerans_Agy99 LGVLVVCAGLELGGPEGQLPSFHIAVA-----------------------
Mb3894|M.bovis_AF2122/97 DGVYKVCKGLEKIPLLGHLWSWELAIP-----------------------
Rv3864|M.tuberculosis_H37Rv DGVYKVCKGLEKIPLLGHLWSWELAIP-----------------------
MLBr_00405|M.leprae_Br4923 LFVRPVAIDLNYIPLVGSVMSASIQAQ-----------------------
Mvan_0656|M.vanbaalenii_PYR-1 GNAIVPALAARALGKHGKAISYGIETG-----------------------
MSMEG_1188|M.smegmatis_MC2_155 DATQPAPAAADATQMAPAASDATVATPTDAAGQVGPELAYSQEPEAEPWA
Mflv_0157|M.gilvum_PYR-GCK -----------------------------------AVAATVPFAMQRVTE
TH_2666|M.thermoresistible__bu -----------------------------------AVAGTAPLASLRYNE
MMAR_5429|M.marinum_M -----------------------------------ICGTALFVAAVALTF
MUL_5045|M.ulcerans_Agy99 -----------------------------------ACGVVQVAAAATLIG
Mb3894|M.bovis_AF2122/97 -----------------------------------MSGIAMAVVGGALLY
Rv3864|M.tuberculosis_H37Rv -----------------------------------MSGIAMAVVGGALLY
MLBr_00405|M.leprae_Br4923 -----------------------------------ACAAAMAAVSGGLAY
Mvan_0656|M.vanbaalenii_PYR-1 -----------------------------------AVASSMPICIWHMTQ
MSMEG_1188|M.smegmatis_MC2_155 EYDEMPMDPLSEFVPEQAEEAGYTTVIAPPPPRMLLVGSALTFVAVSFAT
.
Mflv_0157|M.gilvum_PYR-GCK MVSHSADNADRIRQIGSHYGVVDESAQ-----------------------
TH_2666|M.thermoresistible__bu LTRAVIRNAARMTQAAGEYSSVASAAN-----------------------
MMAR_5429|M.marinum_M LAVTTSRNASAVQAATQRLTAMVAALT-----------------------
MUL_5045|M.ulcerans_Agy99 LANKTSSNASSLRAATQRATEMLAARS-----------------------
Mb3894|M.bovis_AF2122/97 LTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPKL
Rv3864|M.tuberculosis_H37Rv LTIMTLMNATNLRGILGRLIEMLTTLPKFPGLPGLPSLPDIIDGLWPPKL
MLBr_00405|M.leprae_Br4923 LLVQTAIHTAKFVALLARLAHLLASAVAD---------------------
Mvan_0656|M.vanbaalenii_PYR-1 LAGHSARAAETLKDAVALYEQVANEGYSVRM-------------------
MSMEG_1188|M.smegmatis_MC2_155 LAVTVAINVRPAADVRAQPVTPTQSDTVPGRYLPPVPHEPDPVALPVTVL
: .
Mflv_0157|M.gilvum_PYR-GCK ----MPGGLSGAQSGTPAP-------------------------------
TH_2666|M.thermoresistible__bu ----PS--------------------------------------------
MMAR_5429|M.marinum_M -----TGPDAVP--GSPEMPTPPKYCLSEFDLAEDTGPTPPQLPDLG---
MUL_5045|M.ulcerans_Agy99 -----AGSDAIP--GSAGMTAP------------DVG-TPP---------
Mb3894|M.bovis_AF2122/97 PDIPIPGLPDIP--GLPDFKWPPTPGSPLFPDLPSFPGFPGFPSLPGFPG
Rv3864|M.tuberculosis_H37Rv PDIPIPGLPDIP--GLPDFKWPPTPGSPLFPDLPSFPGFP----------
MLBr_00405|M.leprae_Br4923 ----VVSDGVAIIKGIVDHLWHFIAGALTGLKDIVEKIIHWFFGLFSHWW
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1188|M.smegmatis_MC2_155 TPPPAQPVAPNTRTGNNTQPAPQAPPAPQAPPPAAPAPQPPAPQAPAPVP
Mflv_0157|M.gilvum_PYR-GCK ----------------------LRVSESIRGTAGIQQNVAATIDSARSAP
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5429|M.marinum_M -------SAFTDLPGAPEFHLATGTGAGLPDFGAPQLPIPALTGLPTLPG
MUL_5045|M.ulcerans_Agy99 ----------------------SGARPRL---------------------
Mb3894|M.bovis_AF2122/97 LPGFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTE
Rv3864|M.tuberculosis_H37Rv --GFPEFPAIPGFPALPGLPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTE
MLBr_00405|M.leprae_Br4923 SRLHSFFGGIPGLSGATSGLSQVTGLFGVPGLAGSSGLLSGESLLSTENL
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1188|M.smegmatis_MC2_155 IPVPLPPVIVVPPLTPPWTPPWATPTSPTTPPTSTSTPTTTPPTTPSTTP
Mflv_0157|M.gilvum_PYR-GCK DGSAGDVFKTHGVVCTSTAAALKSAELARRSAAEKMHLISTDLSAKLGSS
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5429|M.marinum_M PTNLTDLTSVLAGLPTIAQLSTTLSQLTNLAGPTSTTTQPAQQHTTPADH
MUL_5045|M.ulcerans_Agy99 ----------------------------DVAGDTARIRR-----------
Mb3894|M.bovis_AF2122/97 LAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGGG
Rv3864|M.tuberculosis_H37Rv LAALPDFLGGFAGLPSLGFGNLLSFASLPTVGQVTATMGQLQQLVAAGGG
MLBr_00405|M.leprae_Br4923 PSLAGVGAGLGLGSLPQLAQLHAASTRQGTRSQAGVSAELSTEQFGGQQE
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1188|M.smegmatis_MC2_155 PTTTAPPTSTTTAPPTTSTTTAPTTTTVPTTTAPPTSSVPTTTSAPTTTY
Mflv_0157|M.gilvum_PYR-GCK ATEYSHTEQQNADAVDRQMPPR----------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5429|M.marinum_M PTQDDATDTPDTAAAATTTSG--------------------------ERA
MUL_5045|M.ulcerans_Agy99 --------TPDRGAAYAELLD--------------------------RS-
Mb3894|M.bovis_AF2122/97 PSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEEGAAAGVAEAERA
Rv3864|M.tuberculosis_H37Rv PSQLASMGSQQAQLISSQAQQGGQQHATLVSDKKEDEE----GVAEAERA
MLBr_00405|M.leprae_Br4923 PVSAQGSQGMGGSQGMGGMTPASTKSKKDERKKKKYSEGAAAGTDDAERA
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1188|M.smegmatis_MC2_155 TPPVEEEPTYTPPVEEPTYTAPVEQPSTTVYPDTPSWGDDSSSSGGSSGG
Mflv_0157|M.gilvum_PYR-GCK -----------------------------------
TH_2666|M.thermoresistible__bu -----------------------------------
MMAR_5429|M.marinum_M PLGSTTRPTQQNQDLVV------------------
MUL_5045|M.ulcerans_Agy99 -----------------------------------
Mb3894|M.bovis_AF2122/97 PIDAGTAASQRGQEGTVL-----------------
Rv3864|M.tuberculosis_H37Rv PIDAGTAASQRGQEGTVL-----------------
MLBr_00405|M.leprae_Br4923 PIEVQSGGGKRALAQHVV-----------------
Mvan_0656|M.vanbaalenii_PYR-1 -----------------------------------
MSMEG_1188|M.smegmatis_MC2_155 SRGGSSGSSSDDSSSGGSYGGGSDDSPVTTIFDSP