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MTEPIEPMPSDYVERWLANQQKLFPNGETITYGPGGEECGQYFVNGEWVSERPPNWPNGPAEEMAEDAPK RLLRGSLICLGTETLLGSVLTYLGLGFPDSGDDLLSSASMFDGARSQIADLVPGGGWRGAAAQAYAANNL AQSQRAKLIGDLDRLTAGLVSAQADAVKTARWIVGAEMAVVGGTGACCLYWETLGPAGQVLSLQVALTVC AIALATALGFLFALLSTTSRNASGLHLLTKALAETVTGLLHCSDEIAGVSGAARPPSEFDATHHTASRPE TPDTTDVFANLAGTPELSLPTAPSPGFADFGAPHLPILGLAGMPSLPDSFPDLPNPSGTLAGLAGRVARL NQLANTAAQRVQMISSLAQHGVSQPTTPAKRHPHGQDNAVAAGTAADERAPVDAAAAPRSMTPTAQP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5415 | - | - | 100% (417) | hypothetical protein MMAR_5415 |
| M. marinum M | MMAR_5421 | - | 2e-83 | 47.17% (371) | hypothetical protein MMAR_5421 |
| M. marinum M | MMAR_5422 | - | 2e-72 | 46.05% (354) | hypothetical protein MMAR_5422 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 5e-31 | 28.57% (413) | hypothetical protein Mb3894 |
| M. gilvum PYR-GCK | Mflv_0157 | - | 2e-09 | 24.36% (156) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3864 | - | 5e-30 | 28.68% (401) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 2e-15 | 28.66% (307) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0055 | - | 3e-09 | 21.84% (316) | hypothetical protein MSMEG_0055 |
| M. thermoresistible (build 8) | TH_2666 | - | 8e-07 | 23.73% (177) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_5045 | - | 5e-41 | 42.92% (240) | hypothetical protein MUL_5045 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 7e-10 | 28.17% (142) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK -----------MALGKLWVDANYFYGVADHANMMSSDPALGSAAIATDAA
TH_2666|M.thermoresistible__bu -------------MLDAYSTLNWGKSVVEHPMSAKDHTGWGIAGTGADFV
MMAR_5415|M.marinum_M -MTEPIEPMPSDYVERWLANQQKLFPNGETITYGPGGEECGQYFVNGEWV
MUL_5045|M.ulcerans_Agy99 -----MHPDEAATHNRSFEDLLAYLEP-DAGLFEPDGFESDAWETQFDGF
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
Mvan_0656|M.vanbaalenii_PYR-1 MGLFDFYSDLMQHVGESMQRVDPFGPMGAAGEAVTSLFAVG-NIVGDHGT
MSMEG_0055|M.smegmatis_MC2_155 ---MGVLSDVADFGKDVIDDRDKWADRFKKVGHFIERNAKGDRLERVAKF
Mflv_0157|M.gilvum_PYR-GCK ILMQSLAAVGGSTMGATG--LATSVAT--PIINAGLMTLTAASNTLG-FG
TH_2666|M.thermoresistible__bu TLMQGMTEAG-SGLDQGR--LAKAAAT--PIIRAALLAMMVMSNTCG-VG
MMAR_5415|M.marinum_M SERPPNWPNGPAEEMAEDAPKRLLRGS--LICLGTETLLGSVLTYLG-LG
MUL_5045|M.ulcerans_Agy99 ESDVGEIER-EAEAGAADNPHELCPGT--VVCGATLTILGVMWGWLG-DE
Mb3894|M.bovis_AF2122/97 ----------------------MASGS--GLCKTTSNFIWGQLLLLG-EG
Rv3864|M.tuberculosis_H37Rv ----------------------MASGS--GLCKTTSNFIWGQLLLLG-EG
MLBr_00405|M.leprae_Br4923 -----------------------MSGA--FIIDPTLKAIEAWHALLG-IG
Mvan_0656|M.vanbaalenii_PYR-1 DAMWNLAGDAGDVASVAQSMLPFAKQT--LIIEGGLKMISVMEEQSGGAN
MSMEG_0055|M.smegmatis_MC2_155 GRALGDFSGKFTDFFESNLGKRMVKAARSPILAAGQHVITGMKLTTG-VG
: : : *
Mflv_0157|M.gilvum_PYR-GCK RPEDGERFTDGARQFSEANDELQQAVPPPDWQGDASDAYGLRNTEQQQRA
TH_2666|M.thermoresistible__bu TPEKGDRFEEGAQAFEAAGEALGATKSPESWQGKASNTYTDRNDEQRARA
MMAR_5415|M.marinum_M FPDSGDDLLSSASMFDGARSQIADLVPGGGWRGAAAQAYAANNLAQSQRA
MUL_5045|M.ulcerans_Agy99 SPEQGDRLASSGSLFDDVGAQVAALGPDGGWRGNAAQAYWVQNLAQSRHA
Mb3894|M.bovis_AF2122/97 IPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRA
Rv3864|M.tuberculosis_H37Rv IPDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRA
MLBr_00405|M.leprae_Br4923 VPNDGGVLYSSLSFFEKALEHLAAAFPGDGWLGSAADKYAGQNRKRVDIF
Mvan_0656|M.vanbaalenii_PYR-1 VPSEGESYSDSAHRFNQVGDTLASAMPDDRWRGTAADAYTLANEQQYARA
MSMEG_0055|M.smegmatis_MC2_155 DPENGRRFGEGADHMSAAGRTLDSAYPTSDWDSAASDAYLSQNNGQVTRA
*. * . :. : . * . *:: * * :
Mflv_0157|M.gilvum_PYR-GCK GSMATFDGQIQEVLAEEAGQVQDTRDFVSTRQVMLAAAIPAAITAKLIPP
TH_2666|M.thermoresistible__bu ERMAAIDRTVKEILDAEAHQVDVARKMLDRCQTVLSLSIPAAIAAKAIPF
MMAR_5415|M.marinum_M KLIGDLDRLTAGLVSAQADAVKTARWIVGAEMAVVGGTGACCLYWETLGP
MUL_5045|M.ulcerans_Agy99 TLMADLDRLTAGLVSSQADAVKQARERLSVLIAVVLGVLVVCAGLELGGP
Mb3894|M.bovis_AF2122/97 QVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPL
Rv3864|M.tuberculosis_H37Rv QVMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPL
MLBr_00405|M.leprae_Br4923 QELAELDKELIELIHNQANSVQTTRGILDGAKKALLFVRPVAIDLNYIPL
Mvan_0656|M.vanbaalenii_PYR-1 GKLADADLKVRMALSAEAGEVRTARRMFNQAATVLGNAIVPALAARALGK
MSMEG_0055|M.smegmatis_MC2_155 EALVHADQVVAAVLSREAEQIATTREVLDSEADWLGDMSLVTMATGLIPY
: * : :* : :* . :
Mflv_0157|M.gilvum_PYR-GCK GGAAAAMAIELAAVAATVPFAMQRVTEMVSHSADNADRIRQIGSHYGVVD
TH_2666|M.thermoresistible__bu KGPAISTAIEVAAVAGTAPLASLRYNELTRAVIRNAARMTQAAGEYSSVA
MMAR_5415|M.marinum_M AGQVLSLQVALTVCAIALATALGFLFALLSTTSRNASGLHLLTKALAETV
MUL_5045|M.ulcerans_Agy99 EGQLPSFHIAVAACGVVQVAAAATLIGLANKTSSNASSLRAATQRATEML
Mb3894|M.bovis_AF2122/97 LGHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEML
Rv3864|M.tuberculosis_H37Rv LGHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEML
MLBr_00405|M.leprae_Br4923 VGSVMSASIQAQACAAAMAAVSGGLAYLLVQTAIHTAKFVALLARLAHLL
Mvan_0656|M.vanbaalenii_PYR-1 HGKAISYGIETGAVASSMPICIWHMTQLAGHSARAAETLKDAVALYEQVA
MSMEG_0055|M.smegmatis_MC2_155 VGRAAQTAAEIAMVTKAVGASTDQFMMMRDKADENAAEVRDAIGKYEAVA
* : : .
Mflv_0157|M.gilvum_PYR-GCK ESAQMPG------------------------------------GLSGAQS
TH_2666|M.thermoresistible__bu SAANPS--------------------------------------------
MMAR_5415|M.marinum_M TGLLHCS-----------------------------------DEIAGVSG
MUL_5045|M.ulcerans_Agy99 AARSAGS-----------------------------------DAIPGSAG
Mb3894|M.bovis_AF2122/97 TTLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPG-------LPDIPGLPD
Rv3864|M.tuberculosis_H37Rv TTLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPG-------LPDIPGLPD
MLBr_00405|M.leprae_Br4923 ASAVADVVSDGVAIIKGIVDHLWHFIAG---------------ALTGLKD
Mvan_0656|M.vanbaalenii_PYR-1 NEGYSVRM------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 GDADDTTADDTAGDAPESEPTAAEDSSETSKEDGQSRHENPVAAPSGGGG
Mflv_0157|M.gilvum_PYR-GCK GTPAPLR-------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5415|M.marinum_M AARPPS-------------------------------EFDATHHTASRPE
MUL_5045|M.ulcerans_Agy99 MTAP----------------------------------------------
Mb3894|M.bovis_AF2122/97 FKWPPTPGSPLFPDLPSFPGFPGFPSLPGFPGLPGFPEFPAIPGFPALPG
Rv3864|M.tuberculosis_H37Rv FKWPPTPGSPLFPDLPSFPGFP------------GFPEFPAIPGFPALPG
MLBr_00405|M.leprae_Br4923 IVEKIIHWFFGLFSHWWSR------------------LHSFFGGIPGLSG
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 GATSGGGGGAPSSASSAGPAGTPQVPSPPGFGAANTPTDAQPGAAAASDA
Mflv_0157|M.gilvum_PYR-GCK --------------------------------VSESIRGTAGIQQN----
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5415|M.marinum_M TPDTTDVFANLAGTPELSLPT---APSPGFADFGAPHLPILGLAGMPSL-
MUL_5045|M.ulcerans_Agy99 -------------------------------DVGTP--------------
Mb3894|M.bovis_AF2122/97 LPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLG
Rv3864|M.tuberculosis_H37Rv LPSIPNLFPGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLG
MLBr_00405|M.leprae_Br4923 ATSGLSQVTGLFGVPGLAGSSG-LLSGESLLSTENLPSLAGVGAGLGLGS
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 AGMLGSVMGAMLGPLGGIVGGVVQAAGQALQAATQAGAQAAQLAGQAAAA
Mflv_0157|M.gilvum_PYR-GCK -----------VAATIDSARSAPDGSAGDVFKTHGVVCTSTAAALKSAEL
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5415|M.marinum_M ---------PDSFPDLPNPSGTLAGLAGRVARLNQLANTAAQRVQMISSL
MUL_5045|M.ulcerans_Agy99 ----------------PSGARPRLDVAGDTARIRRTPDRGAAYAELLDRS
Mb3894|M.bovis_AF2122/97 FGNLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQ
Rv3864|M.tuberculosis_H37Rv FGNLLSFASLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQ
MLBr_00405|M.leprae_Br4923 LPQLAQLHAASTRQGTRSQAGVSAELSTEQFGGQQEPVSAQGSQGMGGSQ
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 PDVDRADTDEDTDKDPDAEGDKDSDKRDGEGKEDGTAPRDRESTDAMGAD
Mflv_0157|M.gilvum_PYR-GCK ARRSAAEKMH---LISTDLSAKLGSSATEYSHTEQQNADAVDRQMPPR--
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5415|M.marinum_M AQHGVSQPTT---PAKRHPHGQDNAVAAGTAADERAPVDAAAAPRSMTPT
MUL_5045|M.ulcerans_Agy99 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 AQQGGQQHAT---LVS-DKKEDEEGAAAGVAEAERAPIDAGTAASQRGQE
Rv3864|M.tuberculosis_H37Rv AQQGGQQHAT---LVS-DKKEDEE----GVAEAERAPIDAGTAASQRGQE
MLBr_00405|M.leprae_Br4923 GMGGMTPASTKSKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALA
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 DDDRNAHPQAGSGTDSAGEDDKKPAMTLPPDLQAASALDTGAGSAPVHVG
Mflv_0157|M.gilvum_PYR-GCK -----------------------------
TH_2666|M.thermoresistible__bu -----------------------------
MMAR_5415|M.marinum_M AQP--------------------------
MUL_5045|M.ulcerans_Agy99 -----------------------------
Mb3894|M.bovis_AF2122/97 GTVL-------------------------
Rv3864|M.tuberculosis_H37Rv GTVL-------------------------
MLBr_00405|M.leprae_Br4923 QHVV-------------------------
Mvan_0656|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_0055|M.smegmatis_MC2_155 ADFEHSQLRTVAAATLDHGIPGSAAARGA