For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTDPFWQHYALMELARVLPGQPQAQHLPAPQPEPAPQAAHQPATEDADNPGRLRRGSVLCVVTESLLGGA LAWLGNGFPDRGDGLVCSASMFDGVGAQIATLIPGGSWRGSAAQAYLVQNLAQSRHATLMADLDRLAADL VSSQADAVKTARGVLIAELSLVAVLFTVCVYYEMQGPAGQLWSFKIALAACGAALAVAAGYLVDVAETTW RNGCDLQMATQRLTDMLADLPRQAGAVSSSTEVTLPLAHSPSGSAIAEEAAPTPRTPDPRSALAGLAGSP EFSVPSVAAPGFPDFGAPYLPIPQLAGMPTVPDLSAIVASLPTMAQLSTALRQLNNLTGPTSAIGQLANT ATQHAQMISTLAQQGAQQHATLADHLTTDQDTPDTDGTATGERAPIDAQTLPNQQQRERLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5421 | - | - | 100% (411) | hypothetical protein MMAR_5421 |
| M. marinum M | MMAR_5422 | - | e-125 | 61.18% (389) | hypothetical protein MMAR_5422 |
| M. marinum M | MMAR_5430 | - | e-108 | 55.35% (374) | hypothetical protein MMAR_5430 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3894 | - | 2e-46 | 32.55% (424) | hypothetical protein Mb3894 |
| M. gilvum PYR-GCK | Mflv_0157 | - | 3e-10 | 24.04% (208) | hypothetical protein Mflv_0157 |
| M. tuberculosis H37Rv | Rv3864 | - | 3e-47 | 32.85% (414) | hypothetical protein Rv3864 |
| M. leprae Br4923 | MLBr_00405 | - | 1e-14 | 25.60% (332) | hypothetical protein MLBr_00405 |
| M. abscessus ATCC 19977 | MAB_4924 | - | 2e-05 | 26.24% (141) | hypothetical protein MAB_4924 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0055 | - | 3e-12 | 23.06% (360) | hypothetical protein MSMEG_0055 |
| M. thermoresistible (build 8) | TH_2666 | - | 9e-08 | 25.00% (176) | PUTATIVE putative hypothetical protein MSMEG_0078 |
| M. ulcerans Agy99 | MUL_5045 | - | 3e-53 | 50.21% (235) | hypothetical protein MUL_5045 |
| M. vanbaalenii PYR-1 | Mvan_0656 | - | 3e-09 | 26.52% (132) | hypothetical protein Mvan_0656 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0157|M.gilvum_PYR-GCK ---------MALGKLWVDANYFYGVADHANMMSSDPALGSAA-IATDAAI
TH_2666|M.thermoresistible__bu -----------MLDAYSTLNWGKSVVEHPMSAKDHTGWGIAG-TGADFVT
MMAR_5421|M.marinum_M -------MTDPFWQHYALME--LARVLPGQ----PQAQHLPA-PQPE---
MUL_5045|M.ulcerans_Agy99 ------MHPDEAATHNRSFEDLLAYLEPDAGLFEPDGFESDA-WETQFDG
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 MGVLSDVADFGKDVIDDRDKWADRFKKVGHFIERNAKGDRLE-RVAKFGR
Mvan_0656|M.vanbaalenii_PYR-1 -MGLFDFYSDLMQHVGESMQRVDPFGPMGAAGEAVTSLFAVGNIVGDHGT
MAB_4924|M.abscessus_ATCC_1997 -----------MTTTRYSVRFAAATASVAALLAGTAAVAMADPQPAPVPP
Mflv_0157|M.gilvum_PYR-GCK LMQSLAAVGG---STMGATGLATSVATP-IINAGLMTLTAASNTLG-FGR
TH_2666|M.thermoresistible__bu LMQGMTEAG----SGLDQGRLAKAAATP-IIRAALLAMMVMSNTCG-VGT
MMAR_5421|M.marinum_M ---PAPQAAHQPATEDADNPGRLRRGSV-LCVVTESLLGGALAWLG-NGF
MUL_5045|M.ulcerans_Agy99 FESDVGEIEREAEAGAADNPHELCPGTV-VCGATLTILGVMWGWLG-DES
Mb3894|M.bovis_AF2122/97 ----------------------MASGSG-LCKTTSNFIWGQLLLLG-EGI
Rv3864|M.tuberculosis_H37Rv ----------------------MASGSG-LCKTTSNFIWGQLLLLG-EGI
MLBr_00405|M.leprae_Br4923 -----------------------MSGAF-IIDPTLKAIEAWHALLG-IGV
MSMEG_0055|M.smegmatis_MC2_155 ALGDFSGKFTDFFESNLGKRMVKAARSP-ILAAGQHVITGMKLTTG-VGD
Mvan_0656|M.vanbaalenii_PYR-1 DAMWNLAGDAGDVASVAQSMLPFAKQTL-IIEGGLKMISVMEEQSGGANV
MAB_4924|M.abscessus_ATCC_1997 VPAATANAAVAPAPNAAPAPAVAPTTSANPLQPAAPIAGVAPAADGTLSE
: *
Mflv_0157|M.gilvum_PYR-GCK PEDGERFTDGARQFSEANDELQQAVPPPDWQGDASDAYGLRNTEQQQRAG
TH_2666|M.thermoresistible__bu PEKGDRFEEGAQAFEAAGEALGATKSPESWQGKASNTYTDRNDEQRARAE
MMAR_5421|M.marinum_M PDRGDGLVCSASMFDGVGAQIATLIPGGSWRGSAAQAYLVQNLAQSRHAT
MUL_5045|M.ulcerans_Agy99 PEQGDRLASSGSLFDDVGAQVAALGPDGGWRGNAAQAYWVQNLAQSRHAT
Mb3894|M.bovis_AF2122/97 PDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRAQ
Rv3864|M.tuberculosis_H37Rv PDPGDIFNTGSSLFKQISDKMGLAIPGTNWIGQAAEAYLNQNIAQQLRAQ
MLBr_00405|M.leprae_Br4923 PNDGGVLYSSLSFFEKALEHLAAAFPGDGWLGSAADKYAGQNRKRVDIFQ
MSMEG_0055|M.smegmatis_MC2_155 PENGRRFGEGADHMSAAGRTLDSAYPTSDWDSAASDAYLSQNNGQVTRAE
Mvan_0656|M.vanbaalenii_PYR-1 PSEGESYSDSAHRFNQVGDTLASAMPDDRWRGTAADAYTLANEQQYARAG
MAB_4924|M.abscessus_ATCC_1997 FFASKNVKVEPLTKSSHGVPRISIPIPNNWANVPDPNVPNAYQVIVSKAN
. . * . .
Mflv_0157|M.gilvum_PYR-GCK SMATFDGQIQEVLAEEAGQVQDTRDFVSTRQVMLAAAIPAAITAKLIPPG
TH_2666|M.thermoresistible__bu RMAAIDRTVKEILDAEAHQVDVARKMLDRCQTVLSLSIPAAIAAKAIPFK
MMAR_5421|M.marinum_M LMADLDRLAADLVSSQADAVKTARGVLIAELSLVAVLFTVCVYYEMQGPA
MUL_5045|M.ulcerans_Agy99 LMADLDRLTAGLVSSQADAVKQARERLSVLIAVVLGVLVVCAGLELGGPE
Mb3894|M.bovis_AF2122/97 VMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPLL
Rv3864|M.tuberculosis_H37Rv VMGDLDKLTGNMISNQAKYVSDTRDVLRAMKKMIDGVYKVCKGLEKIPLL
MLBr_00405|M.leprae_Br4923 ELAELDKELIELIHNQANSVQTTRGILDGAKKALLFVRPVAIDLNYIPLV
MSMEG_0055|M.smegmatis_MC2_155 ALVHADQVVAAVLSREAEQIATTREVLDSEADWLGDMSLVTMATGLIPYV
Mvan_0656|M.vanbaalenii_PYR-1 KLADADLKVRMALSAEAGEVRTARRMFNQAATVLGNAIVPALAARALGKH
MAB_4924|M.abscessus_ATCC_1997 GTGIYQSNAQLTMSKLIGEFDTNEAVSHGPVEVKALQGWQPTDASLVTYQ
: : . .
Mflv_0157|M.gilvum_PYR-GCK GAAAAMAIELAAVAATVPFAMQRVTEMVSHSADNADRIRQIGSHYGVVDE
TH_2666|M.thermoresistible__bu GPAISTAIEVAAVAGTAPLASLRYNELTRAVIRNAARMTQAAGEYSSVAS
MMAR_5421|M.marinum_M GQLWSFKIALAACGAALAVAAGYLVDVAETTWRNGCDLQMATQRLTDMLA
MUL_5045|M.ulcerans_Agy99 GQLPSFHIAVAACGVVQVAAAATLIGLANKTSSNASSLRAATQRATEMLA
Mb3894|M.bovis_AF2122/97 GHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEMLT
Rv3864|M.tuberculosis_H37Rv GHLWSWELAIPMSGIAMAVVGGALLYLTIMTLMNATNLRGILGRLIEMLT
MLBr_00405|M.leprae_Br4923 GSVMSASIQAQACAAAMAAVSGGLAYLLVQTAIHTAKFVALLARLAHLLA
MSMEG_0055|M.smegmatis_MC2_155 GRAAQTAAEIAMVTKAVGASTDQFMMMRDKADENAAEVRDAIGKYEAVAG
Mvan_0656|M.vanbaalenii_PYR-1 GKAISYGIETGAVASSMPICIWHMTQLAGHSARAAETLKDAVALYEQVAN
MAB_4924|M.abscessus_ATCC_1997 GFPSSIVEGTFRQDGETLNTSRRAVIITQGKDRFLVQLAVTTTVGNAIAE
* : . :
Mflv_0157|M.gilvum_PYR-GCK SAQMPG---------GLSGAQSGTPAPLRVSESIRGTAGIQQNVAATIDS
TH_2666|M.thermoresistible__bu AANPS---------------------------------------------
MMAR_5421|M.marinum_M DLPRQA---------GAVSSSTEVTLPLAHSPSGSAIA--EEAAPTPRTP
MUL_5045|M.ulcerans_Agy99 ARSAGS---------DAIPGSAGMTAPDVGTP--------------PSGA
Mb3894|M.bovis_AF2122/97 TLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPG
Rv3864|M.tuberculosis_H37Rv TLPKFPGLPGLPSLPDIIDGLWPPKLPDIPIPGLPDIPGLPDFKWPPTPG
MLBr_00405|M.leprae_Br4923 SAVADVVSDGVAIIKGIVDHLWHFIAGALTGLKDIVEKIIHWFFGLFSHW
MSMEG_0055|M.smegmatis_MC2_155 DADDTTADDTAG---DAPESEPTAAEDSSETSKEDGQSRHENPVAAPSGG
Mvan_0656|M.vanbaalenii_PYR-1 EGYSVRM-------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 APATDLIVNGLRFGDAAPVTAPVADPNALADPDAVPGAPATPAAGAPAAA
Mflv_0157|M.gilvum_PYR-GCK ARS-----------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5421|M.marinum_M DPRS----------------------------ALAGLAGSPEFSVPSVAA
MUL_5045|M.ulcerans_Agy99 RPRL----------------------------DVAG--------------
Mb3894|M.bovis_AF2122/97 SPLFPDLPSFPGFPGFPSLPGFPGLPGFPEFPAIPGFPALPGLPSIPNLF
Rv3864|M.tuberculosis_H37Rv SPLFPDLPSFPGFP------------GFPEFPAIPGFPALPGLPSIPNLF
MLBr_00405|M.leprae_Br4923 WSRLHSFFG-----------------------GIPGLSGATSGLSQVTGL
MSMEG_0055|M.smegmatis_MC2_155 GGGATSGGG-----------------------GGAPSSASSAGPAGTPQV
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 DPN-----------------------------------------------
Mflv_0157|M.gilvum_PYR-GCK ----------APDGSAGDVFKTHGVVCTS-------------------TA
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5421|M.marinum_M PGFPDFGAPYLPIPQLAGMPTVPDLSAI--------------------VA
MUL_5045|M.ulcerans_Agy99 --------------DTARIRRTPDRGAA--------------------YA
Mb3894|M.bovis_AF2122/97 PGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLGFGNLLSFA
Rv3864|M.tuberculosis_H37Rv PGLPGLGDLLPGVGDLGKLPTWTELAALPDFLGGFAGLPSLGFGNLLSFA
MLBr_00405|M.leprae_Br4923 FGVPGLAGS-SGLLSGESLLSTENLPSLAGVGAGLGLGSLPQLAQLHAAS
MSMEG_0055|M.smegmatis_MC2_155 PSPPGFGAANTPTDAQPGAAAASDAAGMLGSVMGAMLGPLGGIVGGVVQA
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 ----------APASPAPGVPGLPPLPTLP--------------------A
Mflv_0157|M.gilvum_PYR-GCK AALKSAELARRSAAEKMHLISTDLSAKLGSSATEYSHTEQQNADAVDRQM
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5421|M.marinum_M SLPTMAQLSTALRQLNNLTGPTSAIGQLANTATQHAQMISTLAQQGAQQH
MUL_5045|M.ulcerans_Agy99 ELLDRS--------------------------------------------
Mb3894|M.bovis_AF2122/97 SLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQGGQQH
Rv3864|M.tuberculosis_H37Rv SLPTVGQVTATMGQLQQLVAAGGGPSQLASMGSQQAQLISSQAQQGGQQH
MLBr_00405|M.leprae_Br4923 TRQGTRSQAGVSAELSTEQFGGQQEPVSAQGSQGMGGSQGMGGMTPASTK
MSMEG_0055|M.smegmatis_MC2_155 AGQALQAATQAGAQAAQLAGQAAAAPDVDRADTDEDTDKDPDAEGDKDSD
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 LVPPAPPAA-----------------------------------------
Mflv_0157|M.gilvum_PYR-GCK PPR-----------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5421|M.marinum_M ATLADHLTTDQDTPDTDGTATGERAPIDAQTLPNQQQRERLG--------
MUL_5045|M.ulcerans_Agy99 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 ATLVSDKKEDEEG-AAAGVAEAERAPIDAGTAASQRGQEGTVL-------
Rv3864|M.tuberculosis_H37Rv ATLVSDKKEDEE-----GVAEAERAPIDAGTAASQRGQEGTVL-------
MLBr_00405|M.leprae_Br4923 SKKDERKKKKYSEGAAAGTDDAERAPIEVQSGGGKRALAQHVV-------
MSMEG_0055|M.smegmatis_MC2_155 KRDGEGKEDGTAPRDRESTDAMGADDDDRNAHPQAGSGTDSAGEDDKKPA
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0157|M.gilvum_PYR-GCK --------------------------------------------------
TH_2666|M.thermoresistible__bu --------------------------------------------------
MMAR_5421|M.marinum_M --------------------------------------------------
MUL_5045|M.ulcerans_Agy99 --------------------------------------------------
Mb3894|M.bovis_AF2122/97 --------------------------------------------------
Rv3864|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00405|M.leprae_Br4923 --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155 MTLPPDLQAASALDTGAGSAPVHVGADFEHSQLRTVAAATLDHGIPGSAA
Mvan_0656|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4924|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0157|M.gilvum_PYR-GCK ----
TH_2666|M.thermoresistible__bu ----
MMAR_5421|M.marinum_M ----
MUL_5045|M.ulcerans_Agy99 ----
Mb3894|M.bovis_AF2122/97 ----
Rv3864|M.tuberculosis_H37Rv ----
MLBr_00405|M.leprae_Br4923 ----
MSMEG_0055|M.smegmatis_MC2_155 ARGA
Mvan_0656|M.vanbaalenii_PYR-1 ----
MAB_4924|M.abscessus_ATCC_1997 ----