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HENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAESYGFDSVWLCDHFLTLSPDDYVTQAGIS GEHERRNGRDRPATMPLLEAWTALSALARDTTYIRLGTSVLCNSYRHPAVLAKMAATLDIISEGRLDLGL GAGWFEREFTAYGIPFLPVGDRVTGLGEALEVITAIWTQPDPVYSGRFYTLDGAICDPPPVQTPHPPLWV GGEGDRVHRIAARSAQGINVRWWSPQKVKQRKDFLAQACATAQRDPTTLRFSVTALLAPTDSAEQEAQIR TEFSAVPYDGLIVGPADRCIERINEYYESGVDTFLFTIPDVARSDLIHTVGQEVLPAFD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2559 | - | - | 100% (340) | oxidoreductase |
| M. marinum M | MMAR_5411 | - | 1e-42 | 40.40% (250) | hypothetical protein MMAR_5411 |
| M. marinum M | MMAR_4673 | - | 8e-35 | 31.56% (320) | hypothetical protein MMAR_4673 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 1e-129 | 64.76% (332) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_0268 | - | 6e-39 | 30.38% (316) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 1e-129 | 64.76% (332) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00131 | - | 7e-16 | 30.09% (226) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4277 | - | 8e-43 | 33.23% (316) | luciferase-like monooxygenase superfamily protein |
| M. avium 104 | MAV_0169 | - | 2e-38 | 41.78% (225) | hypothetical protein MAV_0169 |
| M. smegmatis MC2 155 | MSMEG_0702 | - | 6e-39 | 31.65% (316) | monooxygenase |
| M. thermoresistible (build 8) | TH_2824 | - | 7e-43 | 33.12% (314) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3202 | - | 0.0 | 98.82% (340) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0629 | - | 1e-39 | 30.70% (316) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2559|M.marinum_M MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAESYG-FDS
MUL_3202|M.ulcerans_Agy99 MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAESYG-FDS
Mb0815c|M.bovis_AF2122/97 MNAKDD-------PHFGLMLAATVNGLAVGSYREMVVVSQTAEEYG-FDS
Rv0791c|M.tuberculosis_H37Rv MNAKDD-------PHFGLMLAATVNGLAVGSYREMVVVSQTAEEYG-FDS
MSMEG_0702|M.smegmatis_MC2_155 -----------------MDFRVFVEPQQGATYSDQLAVAQAAERLG-YSA
TH_2824|M.thermoresistible__bu -----------------MDFRVFVEPQQGGTYADQLAVARAAEDLG-YSA
Mflv_0268|M.gilvum_PYR-GCK --------MSSV------DFRVFVEPQQGASYADQLAVARTAEQAG-YSA
Mvan_0629|M.vanbaalenii_PYR-1 --------MSTVAATNTPDFRIFVEPQQGASYADQLAVARTAESAG-YSA
MAB_4277|M.abscessus_ATCC_1997 -----------------MDFRVFVEPQQGATYSDQLRVAQAAEELG-FSA
MAV_0169|M.avium_104 -----------------MRFAFKTSPQN-TTWAQMLAVWQAADDIDVYES
MLBr_00131|M.leprae_Br4923 ------------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLG-ADS
: . . .:
MMAR_2559|M.marinum_M VWLCDHFLTLSPDDYVTQAGISGEHERRNGRDR-------PA-TMPLLEA
MUL_3202|M.ulcerans_Agy99 VWLCDHFLTLSPDDYVTQAGISGEHERRDGRDR-------PG-TMPLLEA
Mb0815c|M.bovis_AF2122/97 VWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLEC
Rv0791c|M.tuberculosis_H37Rv VWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLEC
MSMEG_0702|M.smegmatis_MC2_155 FFRSDHYLKMAG-DGLPGP----------------------------TDS
TH_2824|M.thermoresistible__bu FFRSDHYLAMSG-DGLPGP----------------------------TDS
Mflv_0268|M.gilvum_PYR-GCK FFRSDHYLAMAG-DGLPGP----------------------------TDS
Mvan_0629|M.vanbaalenii_PYR-1 FFRSDHYVAMAG-DGLPGP----------------------------TDS
MAB_4277|M.abscessus_ATCC_1997 FFRSDHYLAMGGADGLPGP----------------------------TDA
MAV_0169|M.avium_104 GWTFDHFYPIFS-DSSGPC----------------------------LEG
MLBr_00131|M.leprae_Br4923 YWVGDHLNALVPRSVATPKYLGVAAKVVPKIDAN-------------YEP
: ** : . :
MMAR_2559|M.marinum_M WTALSALAR--DTTYIRLGTSVLCNSYRHPAVLAKMAATLDIISEGRLDL
MUL_3202|M.ulcerans_Agy99 WTALSALAR--DTTYIRLGTSVLCNSYRHPAVLAKMAATLDIISEGRLDL
Mb0815c|M.bovis_AF2122/97 WTALAALSR--DTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDL
Rv0791c|M.tuberculosis_H37Rv WTALAALSR--DTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDL
MSMEG_0702|M.smegmatis_MC2_155 WVTLAGIAR--ETSTIRLGTMVTSATFRYPGPLAISVAQVDEMSGGRVEL
TH_2824|M.thermoresistible__bu WVTLAGIAR--ETTSIRLGTLVTSATFRYPGPLAISVAQVDEMSGGRVEF
Mflv_0268|M.gilvum_PYR-GCK WVTLAGLAR--ETSSIRLGTMVTSATFRHPGPLAISVAQVDEMSGGRVEL
Mvan_0629|M.vanbaalenii_PYR-1 WVTLAGIAR--ETSTIRLGTMVTSATFRYPGPLAISVAQVDEMSGGRVEF
MAB_4277|M.abscessus_ATCC_1997 WVTLGAIAR--ETTAIRLGTLVTSATFRHPGPLAVTVAQVDEMSSGRVDF
MAV_0169|M.avium_104 WTTLTALAQ--ATKRLRLGTLVTGIHYRHPAVLANMAAAVDIISGGRLEL
MLBr_00131|M.leprae_Br4923 WTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKAML
*. * :: . :***. * * *. * .* :. :: *: :
MMAR_2559|M.marinum_M GLGAGWFEREFTAYGIPFLPVGDRVTGLGEALEVITAIWTQP---DPVYS
MUL_3202|M.ulcerans_Agy99 GLGAGWFEREFTAYGIPFLPVGDRVTGLGEALEVITAIWTQP---DPVYS
Mb0815c|M.bovis_AF2122/97 GLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEP---NPTYA
Rv0791c|M.tuberculosis_H37Rv GLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEP---NPTYA
MSMEG_0702|M.smegmatis_MC2_155 GLGAGWFEEEHLAYAIPFPPLGERFDRLTEQLQILTGMWGTPVGDTFDFA
TH_2824|M.thermoresistible__bu GLGSGWFEPEHQAYAIPFPPLGERFDRLTEQLEIITGLWTTPSGEKYDFT
Mflv_0268|M.gilvum_PYR-GCK GLGAGWFEAEHKAYAIPFPPLGERFDRLTEQLEILTGLWTTPTGETFDYS
Mvan_0629|M.vanbaalenii_PYR-1 GIGAGWFEAEHKAYAIPFPPLGERFDRLTEQLEILTGLWTAAPGETFDYS
MAB_4277|M.abscessus_ATCC_1997 GLGAGWFSEEHEAYAIPFPSLGERFDRLEEQLEILTGLWTTPTGDTYSYA
MAV_0169|M.avium_104 GIGAGWNEEESGAYGIELGSIRERFDRFEEACAVLTSLLSQ---ETTDFD
MLBr_00131|M.leprae_Br4923 GIGVGE-REGNEPYGVEWTKP---VARFQEALATIRALWDSN-GELVSRE
*:* * .*.: . : * : .:
MMAR_2559|M.marinum_M GRFYTLDGAICDPPPVQTPHPPLWVGGEG-DRVHRIAARSAQGIN-VRWW
MUL_3202|M.ulcerans_Agy99 GRFYTLDGAICDPPPVQTPHPPLWVGGEG-DRVHRIAARSAQGIN-VRWW
Mb0815c|M.bovis_AF2122/97 GRFYTLDGATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQGLN-VRWW
Rv0791c|M.tuberculosis_H37Rv GRFYTLDGATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQGLN-VRWW
MSMEG_0702|M.smegmatis_MC2_155 GTHYTVKDSPGLPKPVQTPHPPIIIGGQGAKRTPALAAQFASEFN-IPFV
TH_2824|M.thermoresistible__bu GKHYTVVDSPGLPKPVQDPYPPIIIGGQGPKRTPALAARFANEFN-IPFV
Mflv_0268|M.gilvum_PYR-GCK GTHYSIADSPALPKPAQSPRPPIVIGGRGAKRTPALTARFADEFN-IPFV
Mvan_0629|M.vanbaalenii_PYR-1 GRHYSIVDSPALPKPAQRPHPPIIIGGGGAKRTPALAARFADEFN-IPFV
MAB_4277|M.abscessus_ATCC_1997 GKHYTVTDSPALPKPVQEPHPPIVIGGLGVKRTPALAARFATEFN-LPFQ
MAV_0169|M.avium_104 GKFYQLKGARNEPKGPQRPHPPICIGGSGEKRTLRITARYAQHWN-FVGG
MLBr_00131|M.leprae_Br4923 SQFFPLHNALFDLPPYRGKWPEIWVAAHG-PRMLQATGRYADAWIPIVLV
. .: : .: : * : :.. * * :.: * .
MMAR_2559|M.marinum_M SPQKVKQRKDFLAQACATAQRDPTTLRFSVTALLAP----TDSAEQEAQI
MUL_3202|M.ulcerans_Agy99 LPQKVKQRKDFLAQTCATAQRDPTTLRFSVTALLAP----TDSAEQEAQI
Mb0815c|M.bovis_AF2122/97 SPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAP----TQSGEEEVRI
Rv0791c|M.tuberculosis_H37Rv SPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAP----TQSGEEEVRI
MSMEG_0702|M.smegmatis_MC2_155 PLDTLKTQFERVAAAVEGAGRSADSMIYSAAFVLCAGADEAQIAKRAAAI
TH_2824|M.thermoresistible__bu RLDALKAQFERVAAAVAEAGREPDSMIYSAAFVLCAGRDDAEIARRAAAI
Mflv_0268|M.gilvum_PYR-GCK PLDELTTQYARVAAAVEDAGRAKDSLTYSAAFVVCVGRDDAEIARRAAAI
Mvan_0629|M.vanbaalenii_PYR-1 PLDTLTEQYGRVAAAVEQAGRAKDSLIYSAAFVLCVGRDETEIARRAAAI
MAB_4277|M.abscessus_ATCC_1997 PVDVITDQYARVAHAVEAAGRPADSMTYSAAFALCIGDTDADIARRAANI
MAV_0169|M.avium_104 PPDVFAHKRDVLASHCADIGRDPKEILLSAHLRLEPDLDYGKVIDDAAAL
MLBr_00131|M.leprae_Br4923 RPTDYSCALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVDEALDSV
: * : :. : . :
MMAR_2559|M.marinum_M RTEFSAVPYD----------------------------------------
MUL_3202|M.ulcerans_Agy99 RTEFSAVPYD----------------------------------------
Mb0815c|M.bovis_AF2122/97 REEFASIPEP----------------------------------------
Rv0791c|M.tuberculosis_H37Rv REEFASIPEP----------------------------------------
MSMEG_0702|M.smegmatis_MC2_155 GREVDELRSN----------------------------------------
TH_2824|M.thermoresistible__bu NREVDELRSN----------------------------------------
Mflv_0268|M.gilvum_PYR-GCK GREVDEMRSN----------------------------------------
Mvan_0629|M.vanbaalenii_PYR-1 GREVDELRSN----------------------------------------
MAB_4277|M.abscessus_ATCC_1997 GREVEEITEN----------------------------------------
MAV_0169|M.avium_104 AAEGLDLG------------------------------------------
MLBr_00131|M.leprae_Br4923 LVRMIALGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKV
. :
MMAR_2559|M.marinum_M -------GLIVGPADRCIERINEYYESGVDTFLFTIPDVARSDLIHTVGQ
MUL_3202|M.ulcerans_Agy99 -------GLIVGPADRCIERINEYYESGVDTFLFTIPDVARSDLIHTVGQ
Mb0815c|M.bovis_AF2122/97 -------GLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGS
Rv0791c|M.tuberculosis_H37Rv -------GLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGS
MSMEG_0702|M.smegmatis_MC2_155 -------SPLVGTSTEIVDKLGPFIEAGVQRVYLQVLDMSDLDHVEFFAN
TH_2824|M.thermoresistible__bu -------SPVVGTPAEIVDRLGPFIEAGVQRVYLQLLDMSDLDHLELIAT
Mflv_0268|M.gilvum_PYR-GCK -------SPTVGTPAEVVDKLGPFLEAGVERVYLQVLDMSDLEHVEFFAE
Mvan_0629|M.vanbaalenii_PYR-1 -------SPVVGTPGEVVDKLRPFLEAGVQRIYLQLLDMSDLDHVQFFAE
MAB_4277|M.abscessus_ATCC_1997 -------SPLAGTPDAVAEKLSIYVDAGVQRVYVQLLDIRDLDHLEFFAS
MAV_0169|M.avium_104 -----------------IVYLPPPHDPAVLEPLAEAIRDSGLLRS-----
MLBr_00131|M.leprae_Br4923 PAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSA
: : .:
MMAR_2559|M.marinum_M EVLPAFD-------
MUL_3202|M.ulcerans_Agy99 EVLPAFD-------
Mb0815c|M.bovis_AF2122/97 DIIPRVKTEVTIP-
Rv0791c|M.tuberculosis_H37Rv DIIPRVKTEVTIP-
MSMEG_0702|M.smegmatis_MC2_155 EVVRQFS-------
TH_2824|M.thermoresistible__bu QVVPQLR-------
Mflv_0268|M.gilvum_PYR-GCK QVIPQIH-------
Mvan_0629|M.vanbaalenii_PYR-1 QVIPRIG-------
MAB_4277|M.abscessus_ATCC_1997 TVIPQFS-------
MAV_0169|M.avium_104 --------------
MLBr_00131|M.leprae_Br4923 LLPHARVLRGLKKL