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MSYVIATPDMLAAAASDLTNIGSTLGAANSAALARTTGLLAAAEDEVSTAIASLFSASAQEYQMVSTRAA HLHAEFVHSLTRAGAAYAAAEAVNASPLQTLEQNVLAAINAPSQALTARPLFGDGADGAPGTGQNGGDGG WLIGNGGNGGSGAPGGNGGAGGSAGLWGRGGNGGAGGTGVAGGAGGNGGSGGANGLLGGGWGPFGGASGG AGGAGGAGGIGVAGGLGGDGGAGGAGGAGGANSQLLSLWGSAGAGGAGGIGGAGGAGTDGSAGGIGADGG AGGHGGVGGAGGANNAWLGGAAGSGGTGGSGGTGGLGGAGGSGIGYSTGGGAGGAGGAGGDAGTGGAAGA TAFLGSAGVAGSAGNGGHGGNGGSGADGDIGVAGSGAGADGGNGFAGGTGGDGGTGGNTTGGSNGSGGNA GHGGNAGDGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIG VAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIG GNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIGAGADGGNGFAGGTGGDGGTGGNTTGG TNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGG NGADGDIGVAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGG NGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIGAGADGGNGFAGGTGGDGG TGGNTTGGTNGSGGNAGHGGNAGNGADGNVGDYYVSGGTGGMGGDGGDAGTAGLAGTGGSGGTVGAYSAG GAAGNGGTGGAGAQGAPAQFGSTGFAGGDGGAGGDGGTGGGGNGGTNGNGGHGGTGGAGGQGGVGYTDDG SNNATTGGDGGDGGQGGQGGVPGATGTGGTVGMAGNGGAGGAGGQGGDTTTSGNSAGFGGQGGQGGQGGA GLSGLTGGDGYDGGQGGAGGTGGAGGDAVSGAYNGHGGAGGDGGAGGQGGTGHADDGSNNAGAGGNGGMG GQGGQGGGAGAGAGAGSGAGSAGTGGDGGTGGDGGATTTIGHTAGAGGVGGQGGDGGDGLADAASSGGKG GAGGLGGNGGDAVSGAYNGQGGMGGQGGTGGQGGDAGPEGNGGNGGNGGDGGTAGAAGTGGLGGTAGTAG AGGTGGGGGQGGDTTTAGHTAGWGGNGGYGGQGGGGAAGPAGGSGSDGGQGGQGGAGGTGGDAVAGATNG SGGTGGYGGQGGQGGAGGTDDGGDNAGTGGAGGTGGTGGAAGATGSGGTVDLAFPGTAGHGGDGGAGGGG GATTIVGHTAGTGGSGGQGGEGGAAADTGVPGAAGSTGGFGGTGGAGGAGGDAVAGATNGSGGAGGQGGA GAKGGQGYDDDGANNAGVGGNGGEGGTGGSGGAAGTGGDGGTAGAAGTGGTGGDGGKGGATTISGHHAGY GGNAGGGGQGADGAAGPAGGNGYDGGQGGAGGTGGQGGDAVAGATNGYGGQGGIGGTGGQGGGGGADDGS DNAGAGGSGGAGGLGGQSGAASTGGIVGTGGTGFAGDGGDGGAGGQGGATAVSGHTAGAGGTGGTGGTGG DGIDGPADRPGGRGGQGGHGGDGGSGGSAVAGATNGSGGAGGAGGTGGQGGNGYDDDGSDAAGAGGAGGD GGVGGTAGAVGSGGSGGTAGTAGTGGDGGDGGKGGATTTIGSSAGSGGDGGNGGLGGAGAIGPAGADGST GGQGGAGGQGGDGGDAVAGATNGLGGNGGDGGSGGQGGAGGVDDGGGAGTGGQGGEGGQAGDGGVSGSGG LFGGGGDGGHGGQGGLGGTGGDSALGTGGDGGQGGQGGTGGTGGYGAFEGGFGGDGGDGGTGGTGGVGQS GLPGTGGTIGIAGVPGSLPSGSTGGAGGDGGDGGDGGPGSP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5362 | - | - | 100% (2001) | PE-PGRS family protein |
M. marinum M | MMAR_5294 | - | 0.0 | 50.20% (2199) | PE-PGRS family protein |
M. marinum M | MMAR_1594 | - | 0.0 | 47.93% (2314) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 49.60% (2000) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 46.19% (840) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 49.20% (1992) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 1e-09 | 33.33% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 7e-59 | 33.69% (558) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 1e-22 | 44.13% (179) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-173 | 40.16% (1113) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 4e-46 | 42.24% (303) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 50.75% (1139) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 44.36% (877) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Rv3508|M.tuberculosis_H37Rv ----MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADE MUL_4367|M.ulcerans_Agy99 ----MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDE Mb3541|M.bovis_AF2122/97 ----MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADE Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------MMFLAPPGGPGPISAAIQLTSTGSEA MMAR_5362|M.marinum_M ----MSYVIATPDMLAAAASDLTNIGSTLGAANSAALARTTGLLAAAEDE MSMEG_0868|M.smegmatis_MC2_155 ---------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPK TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------MSIIDFILNLFRDPVEAASYVADPEAALANAG MLBr_01183|M.leprae_Br4923 ---MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADD MAV_4827|M.avium_104 MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR Rv3508|M.tuberculosis_H37Rv VSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA--- MUL_4367|M.ulcerans_Agy99 VSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMW Mb3541|M.bovis_AF2122/97 VSARIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATN-- Mflv_5091|M.gilvum_PYR-GCK -----MVTFGGGA------TPTPTSLGAAAVDLSGTSCG----------- Mvan_1264|M.vanbaalenii_PYR-1 TEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG----------- MMAR_5362|M.marinum_M VSTAIASLFSASAQEYQMVSTRAAHLHAEFVHSLTRAGAAYAAAEAVNAS MSMEG_0868|M.smegmatis_MC2_155 FPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQAT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGN--------------- MLBr_01183|M.leprae_Br4923 VSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLT-------------- MAV_4827|M.avium_104 VISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALA---------- Rv3508|M.tuberculosis_H37Rv ---AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGN- MUL_4367|M.ulcerans_Agy99 PLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGN- Mb3541|M.bovis_AF2122/97 ----VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGDGGLLFGS- Mflv_5091|M.gilvum_PYR-GCK ------------------------LICNGQD------GTGQNGGILFGN- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------LICNGQD------GTGQNGGILFGN- MMAR_5362|M.marinum_M PLQTLEQNVLAAINAPSQALTARPLFGDGADGAPGTGQNGGDGGWLIGN- MSMEG_0868|M.smegmatis_MC2_155 STNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------PIHDLSGNLQNYY MLBr_01183|M.leprae_Br4923 -------------------------------------SSSAYAGTETAN- MAV_4827|M.avium_104 -------------------------------------ARRIDNVMLVSAF Rv3508|M.tuberculosis_H37Rv GGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFG MUL_4367|M.ulcerans_Agy99 GGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG----------------- Mb3541|M.bovis_AF2122/97 GGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYG Mflv_5091|M.gilvum_PYR-GCK GGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG----------------- Mvan_1264|M.vanbaalenii_PYR-1 GGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG----------------- MMAR_5362|M.marinum_M GGNGG-SGAPGGNGGAGGSAGLWGRGGNGGAGGTG-------VAGGAGGN MSMEG_0868|M.smegmatis_MC2_155 LGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDP--------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP--------------- MLBr_01183|M.leprae_Br4923 -HDSL--------------------------------------------- MAV_4827|M.avium_104 LAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETS------------- Rv3508|M.tuberculosis_H37Rv VGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELL MUL_4367|M.ulcerans_Agy99 VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAGAGG------------ Mb3541|M.bovis_AF2122/97 RGGVGGAGGIGGGTGGAGG-HAWLFGHGGTGGIGGGPGGNGG-------- Mflv_5091|M.gilvum_PYR-GCK ---------LGGGNGGNGGNAGAFALFGN--------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------LGSGDGGNGGDAGLFSLFGR--------------------- MMAR_5362|M.marinum_M GGSGGANGLLGGGWGPFGGASGGAGGAGGAGGIGVAGGLGGD-------- MSMEG_0868|M.smegmatis_MC2_155 --------AMRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQP------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------IASGNQVMSPSGNVDSFNRGP-------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------DGSIPDVYKQQIRAESYG---------------------- Rv3508|M.tuberculosis_H37Rv FGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGG MUL_4367|M.ulcerans_Agy99 --------------------------SGGSGGWLWG-------------- Mb3541|M.bovis_AF2122/97 ------WLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAG-GTGGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_5362|M.marinum_M -----------GGAGGAGGAGGANSQLLSLWGSAGAGGAGGIGGAGGAGT MSMEG_0868|M.smegmatis_MC2_155 -----------------------LHAAGQQFWVVSPIGSTLGGVINTISG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGG MUL_4367|M.ulcerans_Agy99 ------------NAGQTAGAG-----------------VGGAGGAGGAGD Mb3541|M.bovis_AF2122/97 AGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGG--WLLGNGGNGGLGG Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------GGNGGNGGVGV Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------GGNGGNGGVGI MMAR_5362|M.marinum_M DGSAGGIGADGGAGGHGGVGGAGGANNAWLGGAAGSGGTGGSGGTGGLGG MSMEG_0868|M.smegmatis_MC2_155 QYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------LLDLSFGDLQFGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------DAAGQLSAMVAGL Rv3508|M.tuberculosis_H37Rv AGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGT MUL_4367|M.ulcerans_Agy99 AGDQGVSG------------------------------------------ Mb3541|M.bovis_AF2122/97 DGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGTG-GDG Mflv_5091|M.gilvum_PYR-GCK VGATGAVG------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 AGATGAVG------------------------------------------ MMAR_5362|M.marinum_M AGGSGIGYSTGGGAGGAGGAGGDAGTGGAAGATAFLGSAGVAGSAGNGGH MSMEG_0868|M.smegmatis_MC2_155 NGGNGGVG------------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 RDTTAIGDG----------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 EKLESLPGG----------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQGGAGGAGAAGADAPASTGLTGGTGFAGG-AGGVGGQGGNAIAGG--- MUL_4367|M.ulcerans_Agy99 -----------------VAPGEAGAVGFAGG-AGGAGGAGGNGVGGG--- Mb3541|M.bovis_AF2122/97 GTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGGAGGAGGNGGAGGQAA Mflv_5091|M.gilvum_PYR-GCK ------------------APGVAGATGATGVTSGVVGGNGEDAVGYG--- Mvan_1264|M.vanbaalenii_PYR-1 ------------------APGVAGATGATGVTSNVTGGNGADAVGYG--- MMAR_5362|M.marinum_M GGNGGSGADGDIGVAG-SGAGADGGNGFAGG-TGGDGGTGGNTTGGS--- MSMEG_0868|M.smegmatis_MC2_155 ------------------WAGLDGGNGGSGGLLMGIGGAGGAGGVGA--- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------AVAVGGSNSGPIASGQGSTAVNGDVRD--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------LLLVGSGVDVAPLKQVLQTTTFLDVSVAE--- Rv3508|M.tuberculosis_H37Rv -INGSGGAGGTGGQGGAGGMGGSGADNASG-IGADGGAGGTGGNAGAGGA MUL_4367|M.ulcerans_Agy99 -VNGAGGAGGAGGVGGGGGAGASGVG-----AGVAGGDGGTGGAGGAAGV Mb3541|M.bovis_AF2122/97 LLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGTGGDGGAPGN Mflv_5091|M.gilvum_PYR-GCK ---ATGAAGAAGAAGAAGAAG-------------AVGSAGAAGEAGETGT Mvan_1264|M.vanbaalenii_PYR-1 ---ATGAAGAAGAAGAAGKAG-------------AVGSAGTAGSAGAPGV MMAR_5362|M.marinum_M --NGSGGNAGHGGNAGDGAAGNTGVG-----FATKGGNGGNGGIGGNAGT MSMEG_0868|M.smegmatis_MC2_155 ---DGTSAHVDGGTGGTGGTG--------------GGTGGTGGIGGTGG- TH_3810|M.thermoresistible__bu ---------VD----GDGGSG--------------GRTG----------- MAB_4284c|M.abscessus_ATCC_199 ---SNIINADHGSNVGVDQSQ--------------TRVGGDYTNVSGHGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---EPETALARGAALAAANAP------------LFASSTAALAYAQDPGT Rv3508|M.tuberculosis_H37Rv GGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA-TGATGGT MUL_4367|M.ulcerans_Agy99 GGAAGTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASL-AGQAG-- Mb3541|M.bovis_AF2122/97 GGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADAPAGSGAMGST Mflv_5091|M.gilvum_PYR-GCK WGNAGL--------------PGKAGDAGGAGAVGAAG------------- Mvan_1264|M.vanbaalenii_PYR-1 WGNAGL--------------PGAAGAAGGAGAIGTAG------------- MMAR_5362|M.marinum_M AGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIG----AGADGGN MSMEG_0868|M.smegmatis_MC2_155 -GLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTV------GS TH_3810|M.thermoresistible__bu --LFSKLSR------------GGDGGDGGLG------------------- MAB_4284c|M.abscessus_ATCC_199 ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESP------------ Rv3508|M.tuberculosis_H37Rv GFSGGAGGAGGAGGNTGVG-GTNGSGGQGGTGGAGGAGGAGGVGAD--NP MUL_4367|M.ulcerans_Agy99 -FAGGSGGAGGVGGSAGAG-GVNGSGGDGGAGAAGGAGGASAT------- Mb3541|M.bovis_AF2122/97 GFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLA Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGG--------TGTGANGGAGGVGGVG------------ Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGG--------TGVGGNGGAGQAGGIG------------ MMAR_5362|M.marinum_M GFAGGTGGDGGTGGNTTGG--TNGSGGNAGHGGNAGNGAAGNTGVGFATK MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG---- TH_3810|M.thermoresistible__bu -----------------------GNGGHGGGTGIISLLS----------- MAB_4284c|M.abscessus_ATCC_199 --------------------TEIGSHNQANIGTSTSAG------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------TVVIEKLFLPEDSEPRRRPVLLVG------------ Rv3508|M.tuberculosis_H37Rv TGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGG MUL_4367|M.ulcerans_Agy99 --VAGSGGVGGDGGAGGAAG------------------------------ Mb3541|M.bovis_AF2122/97 AQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADN- Mflv_5091|M.gilvum_PYR-GCK ----GTGAAGAAGGAG---------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----GTGAAGAAGQAG---------------------------------- MMAR_5362|M.marinum_M GGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIG- MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGT----------------------- TH_3810|M.thermoresistible__bu --LAGNGGNGGNGYRTTDNN------------------------------ MAB_4284c|M.abscessus_ATCC_199 ----GSAAVGGNAGLAGNAG------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---SGLAVVGISAVLALEIALAIG-------------------------- Rv3508|M.tuberculosis_H37Rv AGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGG MUL_4367|M.ulcerans_Agy99 ----------------------------------------GGVGAASLGG Mb3541|M.bovis_AF2122/97 ------TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG-TGGQQGNGGNGG Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------------GLGE Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------------TAGE MMAR_5362|M.marinum_M ----------------VAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNG MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------------GRVIAEGTGS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------LAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------------IRT Rv3508|M.tuberculosis_H37Rv TGGTGGVGGAGGAGAA--AAAGSSATGGAGFAGGAGGEGGAGGNSGVGGT MUL_4367|M.ulcerans_Agy99 DGGHAGAGGAGGEGLS--GGFNTGAAGGIGGAGGAGGTGGDSG--GVGGV Mb3541|M.bovis_AF2122/97 NGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGA Mflv_5091|M.gilvum_PYR-GCK TGTTGGAGGVGG-------------QGTAGGTGGVGGIGGAGSTGAVGGV Mvan_1264|M.vanbaalenii_PYR-1 TGVTGGVGGIGG-------------QGTEGGTGGVGGVGGVGATGGAGGV MMAR_5362|M.marinum_M SGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGT MSMEG_0868|M.smegmatis_MC2_155 TAEGTATGGDGGHSTG----------TGIGGNGGIGSVYAYGNNGAVSGT TH_3810|M.thermoresistible__bu ----ALDGGHGGN----------------GGNVGFFSLFNLG-------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN-------------AGLAGNAGLAGNAGLAGNAGLAGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TGTVALQPTPNQHLIVP-----------TEQAPAPPPVQASAPQPKISVP Rv3508|M.tuberculosis_H37Rv NGSGGAGGAGGKGGTGGAGGSGA--DNPTGAGFAGGAGGTGGAAGAGGAG MUL_4367|M.ulcerans_Agy99 NGDGGAGGGGGRGGDGGSSTS------TSGVGGAGGAGGNGGNAGFGVSA Mb3541|M.bovis_AF2122/97 DGNAGNGGDGGVGGNGGNGADN---TTTAAAGTTGGAGGAGGAGGTGGTG Mflv_5091|M.gilvum_PYR-GCK GGKGIQGGQGLQGGKGG----------------DGGAGGKGGDADSMGSA Mvan_1264|M.vanbaalenii_PYR-1 GGKGIQGGQGLQGGQGG----------------DGGTGGTGGDATSMGEA MMAR_5362|M.marinum_M GGTTGAVGNAGHGGNGGNGADG----DIGVAGIGAGADGGNGFAGGTGGD MSMEG_0868|M.smegmatis_MC2_155 -ATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSL TH_3810|M.thermoresistible__bu -GAGGWGGSGVDG---------------------------------VDVV MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG----------------NAGLAGNAGLAGNAGLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 EPVAAPKPLSPPVAAPLP---------------AAPPPAAPPLPEAPPIP Rv3508|M.tuberculosis_H37Rv GATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGG MUL_4367|M.ulcerans_Agy99 GGTG-----------GSAGDGGAGG------------------------- Mb3541|M.bovis_AF2122/97 GAAGTG-TGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGG Mflv_5091|M.gilvum_PYR-GCK GATG--------------GKGGNG-------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GATG--------------GKGGNG-------------------------- MMAR_5362|M.marinum_M GGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGG MSMEG_0868|M.smegmatis_MC2_155 GGRGGT-------SWVQAGYGPTTG------------------------- TH_3810|M.thermoresistible__bu GGN----------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNAG---------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AAPP---------------------------------------------- Rv3508|M.tuberculosis_H37Rv QGGAGGSAGAGGINGAGGAGGNGGDGGDGATGA-----------AGLGDN MUL_4367|M.ulcerans_Agy99 --------GAGGVDGVGGASGNGGAAGAGGAGG-----------SGIG-- Mb3541|M.bovis_AF2122/97 TGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTT Mflv_5091|M.gilvum_PYR-GCK --------GNGGRGGLFGKGGNAGNGADGGTGG----------------- Mvan_1264|M.vanbaalenii_PYR-1 --------GNGGRGSLFGRGGNAGNGGNGGTGG----------------- MMAR_5362|M.marinum_M NAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAG---IGAGAD MSMEG_0868|M.smegmatis_MC2_155 --------GKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNT TH_3810|M.thermoresistible__bu -----------------------PDGGTPG-------------------- MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGNAGLAG----------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------VVPVPVVVPPVPVPVPVRIPVP---------------- Rv3508|M.tuberculosis_H37Rv GGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGA--------- MUL_4367|M.ulcerans_Agy99 --AGIDGGAGGAGGTGGAAGF-----PGGGGTTGAWGTGGA--------- Mb3541|M.bovis_AF2122/97 GGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGK--------- Mflv_5091|M.gilvum_PYR-GCK -----AGGAGGTGGTGG-----------------AGGTGGT--------- Mvan_1264|M.vanbaalenii_PYR-1 -----NGGNGGTGGTGG-----------------NGGTGGT--------- MMAR_5362|M.marinum_M GGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGADGNVGDYYVS MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAA-----Q TH_3810|M.thermoresistible__bu --------------------------AHG--------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGAGGAGDNNFNGGQGGA-------------GGQGGQGGLGGASTTSINA MUL_4367|M.ulcerans_Agy99 GGAGGAG------------------------------------------- Mb3541|M.bovis_AF2122/97 GGTGGDGALAGSSGGAGGK-----------GGNGGDAGKAGTGSAPGTAG Mflv_5091|M.gilvum_PYR-GCK GGTGGIG------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGIG------------------------------------------- MMAR_5362|M.marinum_M GGTGGMGGDGGDAGTAGLAGTGGSGGTVGAYSAGGAAGNGGTGGAGAQGA MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGWVQAYDPNG------------------------------- TH_3810|M.thermoresistible__bu ------------ESHTP--------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv NGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFG--GA MUL_4367|M.ulcerans_Agy99 ----------------------GAGDHGGVGVNPGDSGTAG--------- Mb3541|M.bovis_AF2122/97 TGGDGGKGGNGGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGT Mflv_5091|M.gilvum_PYR-GCK ----------------------GAGSTGGTGGTGGTGGTGG--------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GAGSTGGTGGTGGTGGTGG--------- MMAR_5362|M.marinum_M PAQFGSTGFAGGDGGAGGDGGTGGGGNGGTNGNGGHGGTGGAGGQGGVGY MSMEG_0868|M.smegmatis_MC2_155 ---------------PAGTTIDKGKAAGGNGGDGGFNGTGG--------- TH_3810|M.thermoresistible__bu -----------------GVYTDRQ-------GEDGEDGTGT--------- MAB_4284c|M.abscessus_ATCC_199 --------------------------NAGLAGNAGLAGNAG--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------DPVSPPQLLAPPRLSVPQP--------- Rv3508|M.tuberculosis_H37Rv AGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN MUL_4367|M.ulcerans_Agy99 -----------------------------WAGGAGGAGGAGGSAAFNGVN Mb3541|M.bovis_AF2122/97 AGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATP Mflv_5091|M.gilvum_PYR-GCK ------------------------------TGGTGGTGGTGGTGGTGGKG Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------TGGTGGTGGTGGTGGTGGKG MMAR_5362|M.marinum_M TDDGSNNATTGGDGGDGGQGGQGGVPGATGTGGTVGMAGNGGAGGAGGQG MSMEG_0868|M.smegmatis_MC2_155 -----------------------------ATGGRGGDGAGASVWKANGQH TH_3810|M.thermoresistible__bu -----------------------------GIGGRGGNGG-----SSSGTH MAB_4284c|M.abscessus_ATCC_199 ------------------------------LAGNAAVAGNAAVAGNAAVA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------VQPPVRVPQPPSPPQVGGTV Rv3508|M.tuberculosis_H37Rv G-------AGGAGGNGGDGGDGATGAAGLGDNGGVG--GDGGAGGAAGNG MUL_4367|M.ulcerans_Agy99 G-------AGGAGGNGGAGGGGGAGASGIG-AGVAG--GDGGTGGTGG-- Mb3541|M.bovis_AF2122/97 G-------ANGIAGNGGDGGDGAAGAVGISGATGAGDGGHGGTGGAGGNG Mflv_5091|M.gilvum_PYR-GCK G-------TGGTGGAGGTGGDG----------------GTGGTGGTGG-- Mvan_1264|M.vanbaalenii_PYR-1 G-------TGGTGGDGGTGGTG----------------GTGGTGGTGG-- MMAR_5362|M.marinum_M GDTTTSGNSAGFGGQGGQGGQGGAGLSGLTGGDGYD-GGQGGAGGTGGAG MSMEG_0868|M.smegmatis_MC2_155 S-----TGQTDTGGNGGRGGDGGTFVNAGA-------NGNGGAGGAGGVS TH_3810|M.thermoresistible__bu P-----MAE----------------------------------------- MAB_4284c|M.abscessus_ATCC_199 G------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 P------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GNAGVGLT----AKAGDGGAAGNGGN------------------GGAGGA MUL_4367|M.ulcerans_Agy99 -------------AAGTGGAAGTGGT------------------GGAAGA Mb3541|M.bovis_AF2122/97 GTGGAGGSGIDGVGGGTGGTGGNGGN------------------GAIGGA Mflv_5091|M.gilvum_PYR-GCK ----------------TGGTGGTGGT------------------GGAG-- Mvan_1264|M.vanbaalenii_PYR-1 ----------------TGGTGGTGGT------------------GGAG-- MMAR_5362|M.marinum_M GDAVSGAYNGHGGAGGDGGAGGQGGTGHADDGSNNAGAGGNGGMGGQGGQ MSMEG_0868|M.smegmatis_MC2_155 E-----------GEGGTGGHGGDGGR------------------------ TH_3810|M.thermoresistible__bu --------------------DGEHVK------------------------ MAB_4284c|M.abscessus_ATCC_199 ----------------NAAVGGVLNT------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------QSPPQHQTP------------------------ Rv3508|M.tuberculosis_H37Rv GGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGA MUL_4367|M.ulcerans_Agy99 AGS-----------------------------------AGDGGAGGAGGA Mb3541|M.bovis_AF2122/97 GGDAGGSGNSGGNGGTGGKGGNAGAGGAAGSNGGTVGANGTGGDGGNGGA Mflv_5091|M.gilvum_PYR-GCK --------------------------------------DGTGGTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------DGLGGTGGTGGT MMAR_5362|M.marinum_M GGGAGAGAGAGSGAGSAGTGGDGGTGGDGGATTTIGHTAGAGGVGGQGGD MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------GGDGALGGNGGT TH_3810|M.thermoresistible__bu --------------------------------------ALDGRPGLDG-- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------GVSGAIGGSSHV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------PGEGTPPKPDGP Rv3508|M.tuberculosis_H37Rv GGAGTLGVGGSGGTGGDGGDAGSGGGGGFG-----GAAGKAGGGGNGGVG MUL_4367|M.ulcerans_Agy99 GDDGSAGVVS--------GDPG--------------TAGKAGGAG----- Mb3541|M.bovis_AF2122/97 AGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAGGDGIGGVGGGKGGNGAD Mflv_5091|M.gilvum_PYR-GCK GGQG---------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGFG---------------------------------------------- MMAR_5362|M.marinum_M GGDGLADAASSGGKGGAGGLGGNGGDAVSGAYNGQGGMGGQGGTGGQGGD MSMEG_0868|M.smegmatis_MC2_155 GGVGL--------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGAIN--------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GNYG---------------------------------------------- Rv3508|M.tuberculosis_H37Rv GDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGG MUL_4367|M.ulcerans_Agy99 ----------------------GAGGVGGNGVAGGVNGSGGAGGAG---- Mb3541|M.bovis_AF2122/97 GEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGAGGAGGGAN--- Mflv_5091|M.gilvum_PYR-GCK ----------------------GQGGQGGTGGTGGQGGLGGGGGTG---- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GQGGQGGTGGTGGQGGLGGVGGTG---- MMAR_5362|M.marinum_M AGPEGNGGNGGNGGDGGTAGAAGTGGLGGTAGTAGAGGTGGGGGQGG--- MSMEG_0868|M.smegmatis_MC2_155 -------------------------GNGGKGGNGGNGGNGGTYVDPS--- TH_3810|M.thermoresistible__bu -------------------------GNGSHGGNGGHGGRGG--------- MAB_4284c|M.abscessus_ATCC_199 ------------------------ESLGGSGSVGGSTAVGGGAHTG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------GGHVPTPGAGGSGGSGGGHVPTP--- Rv3508|M.tuberculosis_H37Rv DGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGV MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 -------------------------GTAGNGGQGGAGGTGGAGAASSATN Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_5362|M.marinum_M ---------------------DTTTAGHTAGWGGNGGYGGQGGGGAAGPA MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv PGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGG------ MUL_4367|M.ulcerans_Agy99 ----------GAGGTGGAGASGVP-------------------------- Mb3541|M.bovis_AF2122/97 GGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANGNNRS Mflv_5091|M.gilvum_PYR-GCK ----------GQGGTGGTG------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTG------------------------------- MMAR_5362|M.marinum_M GGSGSDGGQGGQGGAGGTGGDAVAGATNGSGGTGGYGGQGGQGGAGGTDD MSMEG_0868|M.smegmatis_MC2_155 --------HTGAGGNGGNGGAGRIRVNNG--------------------- TH_3810|M.thermoresistible__bu --------FLGIGGSGGWG------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------VGGGVSTGVG------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------GAGGSGGSG------------------------------- Rv3508|M.tuberculosis_H37Rv ---LNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAG MUL_4367|M.ulcerans_Agy99 ------------ASVDGGDGGAGGAGG-----------AAGTGGSG---- Mb3541|M.bovis_AF2122/97 SGSFLAAGGTGGAAGDGGQGGQGGAGG-GAGGQGGAGGAGGTGGNGGN-I Mflv_5091|M.gilvum_PYR-GCK -----------------GQGGTGGTGG-----------TGGTGGTG---- Mvan_1264|M.vanbaalenii_PYR-1 -----------------GQGGTGGTGG-----------TGGTGGTG---- MMAR_5362|M.marinum_M GGDNAGTGGAGGTGGTGGAAGATGSGGTVDLAFPGTAGHGGDGGAGGG-- MSMEG_0868|M.smegmatis_MC2_155 ------TATGTATGGNGGNGGNGDADG----------HRGGKGGDGGE-A TH_3810|M.thermoresistible__bu --------------GHGGNGGDTDADG----------GNGGDGGNGG--- MAB_4284c|M.abscessus_ATCC_199 ---------------VGSHVGGGISES----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------GGHVPTPGTGG----------------------- Rv3508|M.tuberculosis_H37Rv VGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALS--QDGNGFAGGQGGQ MUL_4367|M.ulcerans_Agy99 --------GSAGNTGAGGAGGAGGAGGSAASTGVN--GDG---------- Mb3541|M.bovis_AF2122/97 TGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGD Mflv_5091|M.gilvum_PYR-GCK --------------GAGGDGGLGGLGGFG--------------------- Mvan_1264|M.vanbaalenii_PYR-1 --------------GAGGDGGLGGLGGFG--------------------- MMAR_5362|M.marinum_M ---GGATTIVGHTAGTGGSGGQGGEGGAAADTGVPGAAGSTGGFGGTGGA MSMEG_0868|M.smegmatis_MC2_155 LIRATVIGSNASGTATGGDGGNGGTLGATNGTGGA----ATIVAYNVVQA TH_3810|M.thermoresistible__bu ---------------SAGRGGTGGLRGVF--------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------LGGSGSVGGSTAVG--------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------PGGTGGSGG-------------------------- Rv3508|M.tuberculosis_H37Rv GGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTG---VASEGGAGGQGGD MUL_4367|M.ulcerans_Agy99 -------------GAGGAGGVGGLGGDS----------AATAGGGGAGGD Mb3541|M.bovis_AF2122/97 RTVGGGTVPAGSGGQGGNAGGGGAGGQG----------GADGGSGGDGGD Mflv_5091|M.gilvum_PYR-GCK -------------GSGGTGGQGGLGGPG----------GSTGGAGGAGGQ Mvan_1264|M.vanbaalenii_PYR-1 -------------GVGGTGGQGGQGGPG----------GSTGGAGGAGGQ MMAR_5362|M.marinum_M GGAGGDAVAGATNGSGGAGGQGGAGAKGGQGYDDD--GANNAGVGGNGGE MSMEG_0868|M.smegmatis_MC2_155 NPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGD TH_3810|M.thermoresistible__bu ---------------GINGGNGR--------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------GGAHTGVGGGVSTG-------------VGVGSHVGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------GHVPTPGAGTPGGSG---------------GGHLPFP Rv3508|M.tuberculosis_H37Rv GGQGGIGGAGGNAGFGAGVPGDGGIGGTG-GAGGAGGAG-ADGDPS---- MUL_4367|M.ulcerans_Agy99 GGKGGAGGAGVNGVGG----GDGGKGGTG-GAGGAGGAG-SDGIIP---- Mb3541|M.bovis_AF2122/97 AGTGGNGGNGGNRNSGNGTGGAGGNGGGG-ANGGAGGAGGSGGGTG---- Mflv_5091|M.gilvum_PYR-GCK AGTAGKGGLFG---------GSGSAGKAG-ATGAAGASG-GKGAQG---- Mvan_1264|M.vanbaalenii_PYR-1 AGVAGKGGLFG---------GSGSAGTAG-VTGASGASG-GKGAQG---- MMAR_5362|M.marinum_M GGTGGSGGAAGTGGDG-GTAGAAGTGGTG-GDGGKGGATTISGHHAGYGG MSMEG_0868|M.smegmatis_MC2_155 GIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQG---- TH_3810|M.thermoresistible__bu ---AGLGGRGXX----------------------XXGGGVGAAVRS---- MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGGISES--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GAGSTPGGSGG---------GHLPTPGAGTPGGGLGGFGGGHAPAP---- Rv3508|M.tuberculosis_H37Rv --IDGGQG---------------GAGGHGGQGGKGGLNSTGLASAASGDG MUL_4367|M.ulcerans_Agy99 --SNGGLG---------------GNGGNGGNGGQ-----------AFGDG Mb3541|M.bovis_AF2122/97 --GNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGNG Mflv_5091|M.gilvum_PYR-GCK --ATGAQG---------------ATGAQGATG------------------ Mvan_1264|M.vanbaalenii_PYR-1 --ATGAQG---------------ATGAQGATG------------------ MMAR_5362|M.marinum_M NAGGGGQGADGAAGPAGGNGYDGGQGGAGGTGGQGGDAVAGATNGYGGQG MSMEG_0868|M.smegmatis_MC2_155 --GNGGPSW--------------VQSGYGSTLGG---------------- TH_3810|M.thermoresistible__bu --GNG------------------VFSGGG--------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GNGGAGGAGGNG--------GDGDGFIGGSGGTGGTGGDAGVGGLANTGG MUL_4367|M.ulcerans_Agy99 --------------------------VGGAGGIGGKGGNAAIGTIVING- Mb3541|M.bovis_AF2122/97 GNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGG Mflv_5091|M.gilvum_PYR-GCK --------------------------ATGAAGKAGATGAAGAAGAAGSAG Mvan_1264|M.vanbaalenii_PYR-1 --------------------------ATGASGAQGSAGSAGSAGVAGSAG MMAR_5362|M.marinum_M GIGGTGGQGGGGGADDGS-DNAGAGGSGGAGGLGGQSGAASTGGIVGTGG MSMEG_0868|M.smegmatis_MC2_155 --------------------------NATGTATAGKGGEASNGGVAGNGG TH_3810|M.thermoresistible__bu -----------------------------GTPSAGFGVPTT---IQFPAG MAB_4284c|M.abscessus_ATCC_199 -----------------------------LGGSGSVGGSTAVGGGAHTSA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------GGGLGGGGGHAPAPGGGLGGFGG Rv3508|M.tuberculosis_H37Rv T---------------------AGNAGIGGAGGRGGDGGAGDSGAL---- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 T---------------------GGSGGTGGDGGNGGNGGNGADNTANMTA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_5362|M.marinum_M TGFAGDGGDGGAGGQGGATAVSGHTAGAGGTGGTGGTGGDGIDGPADRPG MSMEG_0868|M.smegmatis_MC2_155 N------------------------------------------------- TH_3810|M.thermoresistible__bu S------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IN------------------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 G------------------------------------------------- Rv3508|M.tuberculosis_H37Rv SQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTG-- MUL_4367|M.ulcerans_Agy99 ------------------------GVGGAGGSGGLGGATEDG-------- Mb3541|M.bovis_AF2122/97 QAGGDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGH Mflv_5091|M.gilvum_PYR-GCK -------------------------TTGAQGSAGTNGANGAN-------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------TTGAQGSAGTNGANGAN-------- MMAR_5362|M.marinum_M GRGGQGGHGGDGGSGGSAVAGATNGSGGAGGAGGTGGQGGNGYDDDGSDA MSMEG_0868|M.smegmatis_MC2_155 -----------------------ALVMAAGTTGVATGNTATG-------- TH_3810|M.thermoresistible__bu -----------------------CTSRAVSREGIMPSSRAAS-------- MAB_4284c|M.abscessus_ATCC_199 --------------------------DALGGSGSVGGSTAVG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------HSGGGLGGLGGGHK---------- Rv3508|M.tuberculosis_H37Rv ------------------VASEGGAGGQGGDGGQGGIGGAGGNAGFGAGV MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_5362|M.marinum_M AG-AGGAGGDGGVGGTAGAVGSGGSGGTAGTAGTGGDGGDGGKGGATTTI MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv PGDGGIGGTGGAGGAGGAGADGDPS-IDGGQGGAGGHGGQGGKGGLNSTG MUL_4367|M.ulcerans_Agy99 -----VGGVGCAGGAG----------------------GNGGRGDMLFT- Mb3541|M.bovis_AF2122/97 GEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPR Mflv_5091|M.gilvum_PYR-GCK ------GSQGAAGKAG-------------------------ATG------ Mvan_1264|M.vanbaalenii_PYR-1 ------GSQGAAGKAG-------------------------ATG------ MMAR_5362|M.marinum_M GSSAGSGGDGGNGGLGGAGAIGPAG----ADGSTGGQGGAGGQGGDGGDA MSMEG_0868|M.smegmatis_MC2_155 ------GDGGAATTAG----------------------ATGGAGGFSNIA TH_3810|M.thermoresistible__bu ------ARAGAACASS----------------------TSRSRRSFCCSR MAB_4284c|M.abscessus_ATCC_199 ------GGAHTSAIN----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv LASAASGDGGNGGAGGAGGNGGAGGLG--GGGGTGGTNGNGG-------- MUL_4367|M.ulcerans_Agy99 ----------VGGSGGTGGDGGGGGSA--SGSGTGGSGGTGG-------- Mb3541|M.bovis_AF2122/97 VGGSG-GDGGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGG-------- Mflv_5091|M.gilvum_PYR-GCK ----------TTGATGAAGEDGDAGSG--GSGINGGAGGAGG-------- Mvan_1264|M.vanbaalenii_PYR-1 ----------TTGATGAAGDAGDPGSE--AVDINGGAGGAGG-------- MMAR_5362|M.marinum_M VAGATNGLGGNGGDGGSGGQGGAGGVDDGGGAGTGGQGGEGGQAGDGGVS MSMEG_0868|M.smegmatis_MC2_155 AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVG-------S TH_3810|M.thermoresistible__bu A------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------ESMNSSINASHSSSMNESFGSSMGSHGAAG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------LGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATG MUL_4367|M.ulcerans_Agy99 -------VGGIGGDGKLG-------------------------------- Mb3541|M.bovis_AF2122/97 -------IGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGS Mflv_5091|M.gilvum_PYR-GCK -------AGGEGGEGGDG-------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------AGGEGGEGGAG-------------------------------- MMAR_5362|M.marinum_M GSGGLFGGGGDGGHGGQGGLGGTGGDSALGTGGDGGQGGQGGTGGTGGYG MSMEG_0868|M.smegmatis_MC2_155 KIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv VGNGGNGGDGGNGGDGGNGAPGGFG------GGAGAGGLGGSGAGGGTDG MUL_4367|M.ulcerans_Agy99 ----GFGGDGGDGGDGGFGVIGGQG------GGGGFGGLGGTGAGG-APS Mb3541|M.bovis_AF2122/97 GGTGGDGGTGGGGGNGGTGWNGGKGDTGSG-GGAGDGGKAPAGGTGGAGG Mflv_5091|M.gilvum_PYR-GCK ----GKGGAGAEGGAGGGGGAGGSG-------AGGAGGAGGSGGSGGSGG Mvan_1264|M.vanbaalenii_PYR-1 ----GAGGDGSEGGAGGSGGAGGSG-------TGGAGGAGGSGGSGGSGG MMAR_5362|M.marinum_M AFEGGFGGDGGDGGTGGTGGVGQSGLPGTG-GTIGIAGVPGSLPSGSTGG MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------TGFEAQGHAQGHAS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv DDGNGGSPGTDGS--- MUL_4367|M.ulcerans_Agy99 DKGINGEPGNPG---- Mb3541|M.bovis_AF2122/97 DGGAGGKGGSGGV--- Mflv_5091|M.gilvum_PYR-GCK SGGSGGAAGDSDD--- Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAAGDSD---- MMAR_5362|M.marinum_M AGGDGGDGGDGGPGSP MSMEG_0868|M.smegmatis_MC2_155 ADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ---------------- MAB_4284c|M.abscessus_ATCC_199 ETAHTTLPGAEHH--- MLBr_01183|M.leprae_Br4923 ---------------- MAV_4827|M.avium_104 ----------------