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M. marinum M MMAR_5362 (-)

annotation: PE-PGRS family protein
coordinates: 6482363 - 6488368
length: 2001

MSYVIATPDMLAAAASDLTNIGSTLGAANSAALARTTGLLAAAEDEVSTAIASLFSASAQEYQMVSTRAA
HLHAEFVHSLTRAGAAYAAAEAVNASPLQTLEQNVLAAINAPSQALTARPLFGDGADGAPGTGQNGGDGG
WLIGNGGNGGSGAPGGNGGAGGSAGLWGRGGNGGAGGTGVAGGAGGNGGSGGANGLLGGGWGPFGGASGG
AGGAGGAGGIGVAGGLGGDGGAGGAGGAGGANSQLLSLWGSAGAGGAGGIGGAGGAGTDGSAGGIGADGG
AGGHGGVGGAGGANNAWLGGAAGSGGTGGSGGTGGLGGAGGSGIGYSTGGGAGGAGGAGGDAGTGGAAGA
TAFLGSAGVAGSAGNGGHGGNGGSGADGDIGVAGSGAGADGGNGFAGGTGGDGGTGGNTTGGSNGSGGNA
GHGGNAGDGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIG
VAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIG
GNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIGAGADGGNGFAGGTGGDGGTGGNTTGG
TNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGG
NGADGDIGVAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGG
NGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIGAGADGGNGFAGGTGGDGG
TGGNTTGGTNGSGGNAGHGGNAGNGADGNVGDYYVSGGTGGMGGDGGDAGTAGLAGTGGSGGTVGAYSAG
GAAGNGGTGGAGAQGAPAQFGSTGFAGGDGGAGGDGGTGGGGNGGTNGNGGHGGTGGAGGQGGVGYTDDG
SNNATTGGDGGDGGQGGQGGVPGATGTGGTVGMAGNGGAGGAGGQGGDTTTSGNSAGFGGQGGQGGQGGA
GLSGLTGGDGYDGGQGGAGGTGGAGGDAVSGAYNGHGGAGGDGGAGGQGGTGHADDGSNNAGAGGNGGMG
GQGGQGGGAGAGAGAGSGAGSAGTGGDGGTGGDGGATTTIGHTAGAGGVGGQGGDGGDGLADAASSGGKG
GAGGLGGNGGDAVSGAYNGQGGMGGQGGTGGQGGDAGPEGNGGNGGNGGDGGTAGAAGTGGLGGTAGTAG
AGGTGGGGGQGGDTTTAGHTAGWGGNGGYGGQGGGGAAGPAGGSGSDGGQGGQGGAGGTGGDAVAGATNG
SGGTGGYGGQGGQGGAGGTDDGGDNAGTGGAGGTGGTGGAAGATGSGGTVDLAFPGTAGHGGDGGAGGGG
GATTIVGHTAGTGGSGGQGGEGGAAADTGVPGAAGSTGGFGGTGGAGGAGGDAVAGATNGSGGAGGQGGA
GAKGGQGYDDDGANNAGVGGNGGEGGTGGSGGAAGTGGDGGTAGAAGTGGTGGDGGKGGATTISGHHAGY
GGNAGGGGQGADGAAGPAGGNGYDGGQGGAGGTGGQGGDAVAGATNGYGGQGGIGGTGGQGGGGGADDGS
DNAGAGGSGGAGGLGGQSGAASTGGIVGTGGTGFAGDGGDGGAGGQGGATAVSGHTAGAGGTGGTGGTGG
DGIDGPADRPGGRGGQGGHGGDGGSGGSAVAGATNGSGGAGGAGGTGGQGGNGYDDDGSDAAGAGGAGGD
GGVGGTAGAVGSGGSGGTAGTAGTGGDGGDGGKGGATTTIGSSAGSGGDGGNGGLGGAGAIGPAGADGST
GGQGGAGGQGGDGGDAVAGATNGLGGNGGDGGSGGQGGAGGVDDGGGAGTGGQGGEGGQAGDGGVSGSGG
LFGGGGDGGHGGQGGLGGTGGDSALGTGGDGGQGGQGGTGGTGGYGAFEGGFGGDGGDGGTGGTGGVGQS
GLPGTGGTIGIAGVPGSLPSGSTGGAGGDGGDGGDGGPGSP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_5362--100% (2001)PE-PGRS family protein
M. marinum MMMAR_5294-0.050.20% (2199) PE-PGRS family protein
M. marinum MMMAR_1594-0.047.93% (2314) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.049.60% (2000) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.046.19% (840) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.049.20% (1992) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-0933.33% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-7e-5933.69% (558) hypothetical protein MAB_4284c
M. avium 104MAV_4827-1e-2244.13% (179) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17340.16% (1113) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-4e-4642.24% (303) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.050.75% (1139) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.044.36% (877) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv3508|M.tuberculosis_H37Rv         ----MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADE
MUL_4367|M.ulcerans_Agy99           ----MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDE
Mb3541|M.bovis_AF2122/97            ----MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADE
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------MMFLAPPGGPGPISAAIQLTSTGSEA
MMAR_5362|M.marinum_M               ----MSYVIATPDMLAAAASDLTNIGSTLGAANSAALARTTGLLAAAEDE
MSMEG_0868|M.smegmatis_MC2_155      ---------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPK
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------MSIIDFILNLFRDPVEAASYVADPEAALANAG
MLBr_01183|M.leprae_Br4923          ---MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADD
MAV_4827|M.avium_104                MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA---
MUL_4367|M.ulcerans_Agy99           VSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMW
Mb3541|M.bovis_AF2122/97            VSARIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATN--
Mflv_5091|M.gilvum_PYR-GCK          -----MVTFGGGA------TPTPTSLGAAAVDLSGTSCG-----------
Mvan_1264|M.vanbaalenii_PYR-1       TEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG-----------
MMAR_5362|M.marinum_M               VSTAIASLFSASAQEYQMVSTRAAHLHAEFVHSLTRAGAAYAAAEAVNAS
MSMEG_0868|M.smegmatis_MC2_155      FPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQAT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGN---------------
MLBr_01183|M.leprae_Br4923          VSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLT--------------
MAV_4827|M.avium_104                VISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALA----------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGN-
MUL_4367|M.ulcerans_Agy99           PLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGN-
Mb3541|M.bovis_AF2122/97            ----VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGDGGLLFGS-
Mflv_5091|M.gilvum_PYR-GCK          ------------------------LICNGQD------GTGQNGGILFGN-
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------LICNGQD------GTGQNGGILFGN-
MMAR_5362|M.marinum_M               PLQTLEQNVLAAINAPSQALTARPLFGDGADGAPGTGQNGGDGGWLIGN-
MSMEG_0868|M.smegmatis_MC2_155      STNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------PIHDLSGNLQNYY
MLBr_01183|M.leprae_Br4923          -------------------------------------SSSAYAGTETAN-
MAV_4827|M.avium_104                -------------------------------------ARRIDNVMLVSAF
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFG
MUL_4367|M.ulcerans_Agy99           GGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-----------------
Mb3541|M.bovis_AF2122/97            GGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYG
Mflv_5091|M.gilvum_PYR-GCK          GGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       GGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG-----------------
MMAR_5362|M.marinum_M               GGNGG-SGAPGGNGGAGGSAGLWGRGGNGGAGGTG-------VAGGAGGN
MSMEG_0868|M.smegmatis_MC2_155      LGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDP---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP---------------
MLBr_01183|M.leprae_Br4923          -HDSL---------------------------------------------
MAV_4827|M.avium_104                LAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETS-------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELL
MUL_4367|M.ulcerans_Agy99           VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAGAGG------------
Mb3541|M.bovis_AF2122/97            RGGVGGAGGIGGGTGGAGG-HAWLFGHGGTGGIGGGPGGNGG--------
Mflv_5091|M.gilvum_PYR-GCK          ---------LGGGNGGNGGNAGAFALFGN---------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------LGSGDGGNGGDAGLFSLFGR---------------------
MMAR_5362|M.marinum_M               GGSGGANGLLGGGWGPFGGASGGAGGAGGAGGIGVAGGLGGD--------
MSMEG_0868|M.smegmatis_MC2_155      --------AMRTTVNPQAQLPVPTVASAVLDPTQIVNWLIYQP-------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------IASGNQVMSPSGNVDSFNRGP--------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------DGSIPDVYKQQIRAESYG----------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         FGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------SGGSGGWLWG--------------
Mb3541|M.bovis_AF2122/97            ------WLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAG-GTGGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_5362|M.marinum_M               -----------GGAGGAGGAGGANSQLLSLWGSAGAGGAGGIGGAGGAGT
MSMEG_0868|M.smegmatis_MC2_155      -----------------------LHAAGQQFWVVSPIGSTLGGVINTISG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGG
MUL_4367|M.ulcerans_Agy99           ------------NAGQTAGAG-----------------VGGAGGAGGAGD
Mb3541|M.bovis_AF2122/97            AGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGG--WLLGNGGNGGLGG
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------------GGNGGNGGVGV
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------------GGNGGNGGVGI
MMAR_5362|M.marinum_M               DGSAGGIGADGGAGGHGGVGGAGGANNAWLGGAAGSGGTGGSGGTGGLGG
MSMEG_0868|M.smegmatis_MC2_155      QYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------LLDLSFGDLQFGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------DAAGQLSAMVAGL
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGT
MUL_4367|M.ulcerans_Agy99           AGDQGVSG------------------------------------------
Mb3541|M.bovis_AF2122/97            DGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGTG-GDG
Mflv_5091|M.gilvum_PYR-GCK          VGATGAVG------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGATGAVG------------------------------------------
MMAR_5362|M.marinum_M               AGGSGIGYSTGGGAGGAGGAGGDAGTGGAAGATAFLGSAGVAGSAGNGGH
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGVG------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      RDTTAIGDG-----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                EKLESLPGG-----------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGQGGAGGAGAAGADAPASTGLTGGTGFAGG-AGGVGGQGGNAIAGG---
MUL_4367|M.ulcerans_Agy99           -----------------VAPGEAGAVGFAGG-AGGAGGAGGNGVGGG---
Mb3541|M.bovis_AF2122/97            GTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGGAGGAGGNGGAGGQAA
Mflv_5091|M.gilvum_PYR-GCK          ------------------APGVAGATGATGVTSGVVGGNGEDAVGYG---
Mvan_1264|M.vanbaalenii_PYR-1       ------------------APGVAGATGATGVTSNVTGGNGADAVGYG---
MMAR_5362|M.marinum_M               GGNGGSGADGDIGVAG-SGAGADGGNGFAGG-TGGDGGTGGNTTGGS---
MSMEG_0868|M.smegmatis_MC2_155      ------------------WAGLDGGNGGSGGLLMGIGGAGGAGGVGA---
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------AVAVGGSNSGPIASGQGSTAVNGDVRD---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------LLLVGSGVDVAPLKQVLQTTTFLDVSVAE---
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -INGSGGAGGTGGQGGAGGMGGSGADNASG-IGADGGAGGTGGNAGAGGA
MUL_4367|M.ulcerans_Agy99           -VNGAGGAGGAGGVGGGGGAGASGVG-----AGVAGGDGGTGGAGGAAGV
Mb3541|M.bovis_AF2122/97            LLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGTGGDGGAPGN
Mflv_5091|M.gilvum_PYR-GCK          ---ATGAAGAAGAAGAAGAAG-------------AVGSAGAAGEAGETGT
Mvan_1264|M.vanbaalenii_PYR-1       ---ATGAAGAAGAAGAAGKAG-------------AVGSAGTAGSAGAPGV
MMAR_5362|M.marinum_M               --NGSGGNAGHGGNAGDGAAGNTGVG-----FATKGGNGGNGGIGGNAGT
MSMEG_0868|M.smegmatis_MC2_155      ---DGTSAHVDGGTGGTGGTG--------------GGTGGTGGIGGTGG-
TH_3810|M.thermoresistible__bu      ---------VD----GDGGSG--------------GRTG-----------
MAB_4284c|M.abscessus_ATCC_199      ---SNIINADHGSNVGVDQSQ--------------TRVGGDYTNVSGHGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---EPETALARGAALAAANAP------------LFASSTAALAYAQDPGT
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA-TGATGGT
MUL_4367|M.ulcerans_Agy99           GGAAGTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASL-AGQAG--
Mb3541|M.bovis_AF2122/97            GGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADAPAGSGAMGST
Mflv_5091|M.gilvum_PYR-GCK          WGNAGL--------------PGKAGDAGGAGAVGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       WGNAGL--------------PGAAGAAGGAGAIGTAG-------------
MMAR_5362|M.marinum_M               AGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAGIG----AGADGGN
MSMEG_0868|M.smegmatis_MC2_155      -GLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTV------GS
TH_3810|M.thermoresistible__bu      --LFSKLSR------------GGDGGDGGLG-------------------
MAB_4284c|M.abscessus_ATCC_199      ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESP------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GFSGGAGGAGGAGGNTGVG-GTNGSGGQGGTGGAGGAGGAGGVGAD--NP
MUL_4367|M.ulcerans_Agy99           -FAGGSGGAGGVGGSAGAG-GVNGSGGDGGAGAAGGAGGASAT-------
Mb3541|M.bovis_AF2122/97            GFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLA
Mflv_5091|M.gilvum_PYR-GCK          -AAGTVGTAGATGG--------TGTGANGGAGGVGGVG------------
Mvan_1264|M.vanbaalenii_PYR-1       -VAGAAGTAGATGG--------TGVGGNGGAGQAGGIG------------
MMAR_5362|M.marinum_M               GFAGGTGGDGGTGGNTTGG--TNGSGGNAGHGGNAGNGAAGNTGVGFATK
MSMEG_0868|M.smegmatis_MC2_155      ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG----
TH_3810|M.thermoresistible__bu      -----------------------GNGGHGGGTGIISLLS-----------
MAB_4284c|M.abscessus_ATCC_199      --------------------TEIGSHNQANIGTSTSAG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------TVVIEKLFLPEDSEPRRRPVLLVG------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         TGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGG
MUL_4367|M.ulcerans_Agy99           --VAGSGGVGGDGGAGGAAG------------------------------
Mb3541|M.bovis_AF2122/97            AQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADN-
Mflv_5091|M.gilvum_PYR-GCK          ----GTGAAGAAGGAG----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGAAGAAGQAG----------------------------------
MMAR_5362|M.marinum_M               GGNGGNGGIGGNAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIG-
MSMEG_0868|M.smegmatis_MC2_155      HAIGGNGGNGGNGSTTAAGGNGGTGGT-----------------------
TH_3810|M.thermoresistible__bu      --LAGNGGNGGNGYRTTDNN------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----GSAAVGGNAGLAGNAG------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---SGLAVVGISAVLALEIALAIG--------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGG
MUL_4367|M.ulcerans_Agy99           ----------------------------------------GGVGAASLGG
Mb3541|M.bovis_AF2122/97            ------TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG-TGGQQGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------GLGE
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------------TAGE
MMAR_5362|M.marinum_M               ----------------VAGIGAGADGGNGFAGGTGGDGGTGGNTTGGTNG
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------------GRVIAEGTGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------LAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------------IRT
                                                                                      

Rv3508|M.tuberculosis_H37Rv         TGGTGGVGGAGGAGAA--AAAGSSATGGAGFAGGAGGEGGAGGNSGVGGT
MUL_4367|M.ulcerans_Agy99           DGGHAGAGGAGGEGLS--GGFNTGAAGGIGGAGGAGGTGGDSG--GVGGV
Mb3541|M.bovis_AF2122/97            NGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGA
Mflv_5091|M.gilvum_PYR-GCK          TGTTGGAGGVGG-------------QGTAGGTGGVGGIGGAGSTGAVGGV
Mvan_1264|M.vanbaalenii_PYR-1       TGVTGGVGGIGG-------------QGTEGGTGGVGGVGGVGATGGAGGV
MMAR_5362|M.marinum_M               SGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGGNAGTAGLAGTGGT
MSMEG_0868|M.smegmatis_MC2_155      TAEGTATGGDGGHSTG----------TGIGGNGGIGSVYAYGNNGAVSGT
TH_3810|M.thermoresistible__bu      ----ALDGGHGGN----------------GGNVGFFSLFNLG--------
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGN-------------AGLAGNAGLAGNAGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TGTVALQPTPNQHLIVP-----------TEQAPAPPPVQASAPQPKISVP
                                                                                      

Rv3508|M.tuberculosis_H37Rv         NGSGGAGGAGGKGGTGGAGGSGA--DNPTGAGFAGGAGGTGGAAGAGGAG
MUL_4367|M.ulcerans_Agy99           NGDGGAGGGGGRGGDGGSSTS------TSGVGGAGGAGGNGGNAGFGVSA
Mb3541|M.bovis_AF2122/97            DGNAGNGGDGGVGGNGGNGADN---TTTAAAGTTGGAGGAGGAGGTGGTG
Mflv_5091|M.gilvum_PYR-GCK          GGKGIQGGQGLQGGKGG----------------DGGAGGKGGDADSMGSA
Mvan_1264|M.vanbaalenii_PYR-1       GGKGIQGGQGLQGGQGG----------------DGGTGGTGGDATSMGEA
MMAR_5362|M.marinum_M               GGTTGAVGNAGHGGNGGNGADG----DIGVAGIGAGADGGNGFAGGTGGD
MSMEG_0868|M.smegmatis_MC2_155      -ATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSL
TH_3810|M.thermoresistible__bu      -GAGGWGGSGVDG---------------------------------VDVV
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAG----------------NAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                EPVAAPKPLSPPVAAPLP---------------AAPPPAAPPLPEAPPIP
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGG
MUL_4367|M.ulcerans_Agy99           GGTG-----------GSAGDGGAGG-------------------------
Mb3541|M.bovis_AF2122/97            GAAGTG-TGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGG
Mflv_5091|M.gilvum_PYR-GCK          GATG--------------GKGGNG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GATG--------------GKGGNG--------------------------
MMAR_5362|M.marinum_M               GGTGGNTTGGTNGSGGNAGHGGNAGNGAAGNTGVGFATKGGNGGNGGIGG
MSMEG_0868|M.smegmatis_MC2_155      GGRGGT-------SWVQAGYGPTTG-------------------------
TH_3810|M.thermoresistible__bu      GGN-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAG----------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AAPP----------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         QGGAGGSAGAGGINGAGGAGGNGGDGGDGATGA-----------AGLGDN
MUL_4367|M.ulcerans_Agy99           --------GAGGVDGVGGASGNGGAAGAGGAGG-----------SGIG--
Mb3541|M.bovis_AF2122/97            TGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTT
Mflv_5091|M.gilvum_PYR-GCK          --------GNGGRGGLFGKGGNAGNGADGGTGG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       --------GNGGRGSLFGRGGNAGNGGNGGTGG-----------------
MMAR_5362|M.marinum_M               NAGTAGLAGTGGTGGTTGAVGNAGHGGNGGNGADGDIGVAG---IGAGAD
MSMEG_0868|M.smegmatis_MC2_155      --------GKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNT
TH_3810|M.thermoresistible__bu      -----------------------PDGGTPG--------------------
MAB_4284c|M.abscessus_ATCC_199      ------------LAGNAGLAGNAGLAGNAGLAG-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------VVPVPVVVPPVPVPVPVRIPVP----------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGA---------
MUL_4367|M.ulcerans_Agy99           --AGIDGGAGGAGGTGGAAGF-----PGGGGTTGAWGTGGA---------
Mb3541|M.bovis_AF2122/97            GGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGK---------
Mflv_5091|M.gilvum_PYR-GCK          -----AGGAGGTGGTGG-----------------AGGTGGT---------
Mvan_1264|M.vanbaalenii_PYR-1       -----NGGNGGTGGTGG-----------------NGGTGGT---------
MMAR_5362|M.marinum_M               GGNGFAGGTGGDGGTGGNTTGGTNGSGGNAGHGGNAGNGADGNVGDYYVS
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAA-----Q
TH_3810|M.thermoresistible__bu      --------------------------AHG---------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGGAGDNNFNGGQGGA-------------GGQGGQGGLGGASTTSINA
MUL_4367|M.ulcerans_Agy99           GGAGGAG-------------------------------------------
Mb3541|M.bovis_AF2122/97            GGTGGDGALAGSSGGAGGK-----------GGNGGDAGKAGTGSAPGTAG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGIG-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGIG-------------------------------------------
MMAR_5362|M.marinum_M               GGTGGMGGDGGDAGTAGLAGTGGSGGTVGAYSAGGAAGNGGTGGAGAQGA
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGNGWVQAYDPNG-------------------------------
TH_3810|M.thermoresistible__bu      ------------ESHTP---------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         NGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFG--GA
MUL_4367|M.ulcerans_Agy99           ----------------------GAGDHGGVGVNPGDSGTAG---------
Mb3541|M.bovis_AF2122/97            TGGDGGKGGNGGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGT
Mflv_5091|M.gilvum_PYR-GCK          ----------------------GAGSTGGTGGTGGTGGTGG---------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------GAGSTGGTGGTGGTGGTGG---------
MMAR_5362|M.marinum_M               PAQFGSTGFAGGDGGAGGDGGTGGGGNGGTNGNGGHGGTGGAGGQGGVGY
MSMEG_0868|M.smegmatis_MC2_155      ---------------PAGTTIDKGKAAGGNGGDGGFNGTGG---------
TH_3810|M.thermoresistible__bu      -----------------GVYTDRQ-------GEDGEDGTGT---------
MAB_4284c|M.abscessus_ATCC_199      --------------------------NAGLAGNAGLAGNAG---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------DPVSPPQLLAPPRLSVPQP---------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN
MUL_4367|M.ulcerans_Agy99           -----------------------------WAGGAGGAGGAGGSAAFNGVN
Mb3541|M.bovis_AF2122/97            AGAGGAGGNGGKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATP
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------TGGTGGTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------TGGTGGTGGTGGTGGTGGKG
MMAR_5362|M.marinum_M               TDDGSNNATTGGDGGDGGQGGQGGVPGATGTGGTVGMAGNGGAGGAGGQG
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------ATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu      -----------------------------GIGGRGGNGG-----SSSGTH
MAB_4284c|M.abscessus_ATCC_199      ------------------------------LAGNAAVAGNAAVAGNAAVA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------VQPPVRVPQPPSPPQVGGTV
                                                                                      

Rv3508|M.tuberculosis_H37Rv         G-------AGGAGGNGGDGGDGATGAAGLGDNGGVG--GDGGAGGAAGNG
MUL_4367|M.ulcerans_Agy99           G-------AGGAGGNGGAGGGGGAGASGIG-AGVAG--GDGGTGGTGG--
Mb3541|M.bovis_AF2122/97            G-------ANGIAGNGGDGGDGAAGAVGISGATGAGDGGHGGTGGAGGNG
Mflv_5091|M.gilvum_PYR-GCK          G-------TGGTGGAGGTGGDG----------------GTGGTGGTGG--
Mvan_1264|M.vanbaalenii_PYR-1       G-------TGGTGGDGGTGGTG----------------GTGGTGGTGG--
MMAR_5362|M.marinum_M               GDTTTSGNSAGFGGQGGQGGQGGAGLSGLTGGDGYD-GGQGGAGGTGGAG
MSMEG_0868|M.smegmatis_MC2_155      S-----TGQTDTGGNGGRGGDGGTFVNAGA-------NGNGGAGGAGGVS
TH_3810|M.thermoresistible__bu      P-----MAE-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G-------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                P-------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GNAGVGLT----AKAGDGGAAGNGGN------------------GGAGGA
MUL_4367|M.ulcerans_Agy99           -------------AAGTGGAAGTGGT------------------GGAAGA
Mb3541|M.bovis_AF2122/97            GTGGAGGSGIDGVGGGTGGTGGNGGN------------------GAIGGA
Mflv_5091|M.gilvum_PYR-GCK          ----------------TGGTGGTGGT------------------GGAG--
Mvan_1264|M.vanbaalenii_PYR-1       ----------------TGGTGGTGGT------------------GGAG--
MMAR_5362|M.marinum_M               GDAVSGAYNGHGGAGGDGGAGGQGGTGHADDGSNNAGAGGNGGMGGQGGQ
MSMEG_0868|M.smegmatis_MC2_155      E-----------GEGGTGGHGGDGGR------------------------
TH_3810|M.thermoresistible__bu      --------------------DGEHVK------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------NAAVGGVLNT------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------QSPPQHQTP------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGA
MUL_4367|M.ulcerans_Agy99           AGS-----------------------------------AGDGGAGGAGGA
Mb3541|M.bovis_AF2122/97            GGDAGGSGNSGGNGGTGGKGGNAGAGGAAGSNGGTVGANGTGGDGGNGGA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------DGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------DGLGGTGGTGGT
MMAR_5362|M.marinum_M               GGGAGAGAGAGSGAGSAGTGGDGGTGGDGGATTTIGHTAGAGGVGGQGGD
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------GGDGALGGNGGT
TH_3810|M.thermoresistible__bu      --------------------------------------ALDGRPGLDG--
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------GVSGAIGGSSHV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------PGEGTPPKPDGP
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGTLGVGGSGGTGGDGGDAGSGGGGGFG-----GAAGKAGGGGNGGVG
MUL_4367|M.ulcerans_Agy99           GDDGSAGVVS--------GDPG--------------TAGKAGGAG-----
Mb3541|M.bovis_AF2122/97            AGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAGGDGIGGVGGGKGGNGAD
Mflv_5091|M.gilvum_PYR-GCK          GGQG----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGFG----------------------------------------------
MMAR_5362|M.marinum_M               GGDGLADAASSGGKGGAGGLGGNGGDAVSGAYNGQGGMGGQGGTGGQGGD
MSMEG_0868|M.smegmatis_MC2_155      GGVGL---------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGAIN---------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GNYG----------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGG
MUL_4367|M.ulcerans_Agy99           ----------------------GAGGVGGNGVAGGVNGSGGAGGAG----
Mb3541|M.bovis_AF2122/97            GEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGAGGAAGAGGAGGGAN---
Mflv_5091|M.gilvum_PYR-GCK          ----------------------GQGGQGGTGGTGGQGGLGGGGGTG----
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------GQGGQGGTGGTGGQGGLGGVGGTG----
MMAR_5362|M.marinum_M               AGPEGNGGNGGNGGDGGTAGAAGTGGLGGTAGTAGAGGTGGGGGQGG---
MSMEG_0868|M.smegmatis_MC2_155      -------------------------GNGGKGGNGGNGGNGGTYVDPS---
TH_3810|M.thermoresistible__bu      -------------------------GNGSHGGNGGHGGRGG---------
MAB_4284c|M.abscessus_ATCC_199      ------------------------ESLGGSGSVGGSTAVGGGAHTG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------GGHVPTPGAGGSGGSGGGHVPTP---
                                                                                      

Rv3508|M.tuberculosis_H37Rv         DGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mb3541|M.bovis_AF2122/97            -------------------------GTAGNGGQGGAGGTGGAGAASSATN
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_5362|M.marinum_M               ---------------------DTTTAGHTAGWGGNGGYGGQGGGGAAGPA
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         PGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGG------
MUL_4367|M.ulcerans_Agy99           ----------GAGGTGGAGASGVP--------------------------
Mb3541|M.bovis_AF2122/97            GGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANGNNRS
Mflv_5091|M.gilvum_PYR-GCK          ----------GQGGTGGTG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------GTGGTGGTG-------------------------------
MMAR_5362|M.marinum_M               GGSGSDGGQGGQGGAGGTGGDAVAGATNGSGGTGGYGGQGGQGGAGGTDD
MSMEG_0868|M.smegmatis_MC2_155      --------HTGAGGNGGNGGAGRIRVNNG---------------------
TH_3810|M.thermoresistible__bu      --------FLGIGGSGGWG-------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------VGGGVSTGVG-------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------GAGGSGGSG-------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---LNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAG
MUL_4367|M.ulcerans_Agy99           ------------ASVDGGDGGAGGAGG-----------AAGTGGSG----
Mb3541|M.bovis_AF2122/97            SGSFLAAGGTGGAAGDGGQGGQGGAGG-GAGGQGGAGGAGGTGGNGGN-I
Mflv_5091|M.gilvum_PYR-GCK          -----------------GQGGTGGTGG-----------TGGTGGTG----
Mvan_1264|M.vanbaalenii_PYR-1       -----------------GQGGTGGTGG-----------TGGTGGTG----
MMAR_5362|M.marinum_M               GGDNAGTGGAGGTGGTGGAAGATGSGGTVDLAFPGTAGHGGDGGAGGG--
MSMEG_0868|M.smegmatis_MC2_155      ------TATGTATGGNGGNGGNGDADG----------HRGGKGGDGGE-A
TH_3810|M.thermoresistible__bu      --------------GHGGNGGDTDADG----------GNGGDGGNGG---
MAB_4284c|M.abscessus_ATCC_199      ---------------VGSHVGGGISES-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------GGHVPTPGTGG-----------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALS--QDGNGFAGGQGGQ
MUL_4367|M.ulcerans_Agy99           --------GSAGNTGAGGAGGAGGAGGSAASTGVN--GDG----------
Mb3541|M.bovis_AF2122/97            TGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGD
Mflv_5091|M.gilvum_PYR-GCK          --------------GAGGDGGLGGLGGFG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------GAGGDGGLGGLGGFG---------------------
MMAR_5362|M.marinum_M               ---GGATTIVGHTAGTGGSGGQGGEGGAAADTGVPGAAGSTGGFGGTGGA
MSMEG_0868|M.smegmatis_MC2_155      LIRATVIGSNASGTATGGDGGNGGTLGATNGTGGA----ATIVAYNVVQA
TH_3810|M.thermoresistible__bu      ---------------SAGRGGTGGLRGVF---------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------LGGSGSVGGSTAVG---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------PGGTGGSGG--------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTG---VASEGGAGGQGGD
MUL_4367|M.ulcerans_Agy99           -------------GAGGAGGVGGLGGDS----------AATAGGGGAGGD
Mb3541|M.bovis_AF2122/97            RTVGGGTVPAGSGGQGGNAGGGGAGGQG----------GADGGSGGDGGD
Mflv_5091|M.gilvum_PYR-GCK          -------------GSGGTGGQGGLGGPG----------GSTGGAGGAGGQ
Mvan_1264|M.vanbaalenii_PYR-1       -------------GVGGTGGQGGQGGPG----------GSTGGAGGAGGQ
MMAR_5362|M.marinum_M               GGAGGDAVAGATNGSGGAGGQGGAGAKGGQGYDDD--GANNAGVGGNGGE
MSMEG_0868|M.smegmatis_MC2_155      NPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGD
TH_3810|M.thermoresistible__bu      ---------------GINGGNGR---------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------GGAHTGVGGGVSTG-------------VGVGSHVGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------GHVPTPGAGTPGGSG---------------GGHLPFP
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGQGGIGGAGGNAGFGAGVPGDGGIGGTG-GAGGAGGAG-ADGDPS----
MUL_4367|M.ulcerans_Agy99           GGKGGAGGAGVNGVGG----GDGGKGGTG-GAGGAGGAG-SDGIIP----
Mb3541|M.bovis_AF2122/97            AGTGGNGGNGGNRNSGNGTGGAGGNGGGG-ANGGAGGAGGSGGGTG----
Mflv_5091|M.gilvum_PYR-GCK          AGTAGKGGLFG---------GSGSAGKAG-ATGAAGASG-GKGAQG----
Mvan_1264|M.vanbaalenii_PYR-1       AGVAGKGGLFG---------GSGSAGTAG-VTGASGASG-GKGAQG----
MMAR_5362|M.marinum_M               GGTGGSGGAAGTGGDG-GTAGAAGTGGTG-GDGGKGGATTISGHHAGYGG
MSMEG_0868|M.smegmatis_MC2_155      GIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQG----
TH_3810|M.thermoresistible__bu      ---AGLGGRGXX----------------------XXGGGVGAAVRS----
MAB_4284c|M.abscessus_ATCC_199      GISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGGISES---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GAGSTPGGSGG---------GHLPTPGAGTPGGGLGGFGGGHAPAP----
                                                                                      

Rv3508|M.tuberculosis_H37Rv         --IDGGQG---------------GAGGHGGQGGKGGLNSTGLASAASGDG
MUL_4367|M.ulcerans_Agy99           --SNGGLG---------------GNGGNGGNGGQ-----------AFGDG
Mb3541|M.bovis_AF2122/97            --GNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGNG
Mflv_5091|M.gilvum_PYR-GCK          --ATGAQG---------------ATGAQGATG------------------
Mvan_1264|M.vanbaalenii_PYR-1       --ATGAQG---------------ATGAQGATG------------------
MMAR_5362|M.marinum_M               NAGGGGQGADGAAGPAGGNGYDGGQGGAGGTGGQGGDAVAGATNGYGGQG
MSMEG_0868|M.smegmatis_MC2_155      --GNGGPSW--------------VQSGYGSTLGG----------------
TH_3810|M.thermoresistible__bu      --GNG------------------VFSGGG---------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GNGGAGGAGGNG--------GDGDGFIGGSGGTGGTGGDAGVGGLANTGG
MUL_4367|M.ulcerans_Agy99           --------------------------VGGAGGIGGKGGNAAIGTIVING-
Mb3541|M.bovis_AF2122/97            GNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------ATGAAGKAGATGAAGAAGAAGSAG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------ATGASGAQGSAGSAGSAGVAGSAG
MMAR_5362|M.marinum_M               GIGGTGGQGGGGGADDGS-DNAGAGGSGGAGGLGGQSGAASTGGIVGTGG
MSMEG_0868|M.smegmatis_MC2_155      --------------------------NATGTATAGKGGEASNGGVAGNGG
TH_3810|M.thermoresistible__bu      -----------------------------GTPSAGFGVPTT---IQFPAG
MAB_4284c|M.abscessus_ATCC_199      -----------------------------LGGSGSVGGSTAVGGGAHTSA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------GGGLGGGGGHAPAPGGGLGGFGG
                                                                                      

Rv3508|M.tuberculosis_H37Rv         T---------------------AGNAGIGGAGGRGGDGGAGDSGAL----
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mb3541|M.bovis_AF2122/97            T---------------------GGSGGTGGDGGNGGNGGNGADNTANMTA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_5362|M.marinum_M               TGFAGDGGDGGAGGQGGATAVSGHTAGAGGTGGTGGTGGDGIDGPADRPG
MSMEG_0868|M.smegmatis_MC2_155      N-------------------------------------------------
TH_3810|M.thermoresistible__bu      S-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IN------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                G-------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         SQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTG--
MUL_4367|M.ulcerans_Agy99           ------------------------GVGGAGGSGGLGGATEDG--------
Mb3541|M.bovis_AF2122/97            QAGGDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGH
Mflv_5091|M.gilvum_PYR-GCK          -------------------------TTGAQGSAGTNGANGAN--------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------TTGAQGSAGTNGANGAN--------
MMAR_5362|M.marinum_M               GRGGQGGHGGDGGSGGSAVAGATNGSGGAGGAGGTGGQGGNGYDDDGSDA
MSMEG_0868|M.smegmatis_MC2_155      -----------------------ALVMAAGTTGVATGNTATG--------
TH_3810|M.thermoresistible__bu      -----------------------CTSRAVSREGIMPSSRAAS--------
MAB_4284c|M.abscessus_ATCC_199      --------------------------DALGGSGSVGGSTAVG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------HSGGGLGGLGGGHK----------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ------------------VASEGGAGGQGGDGGQGGIGGAGGNAGFGAGV
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_5362|M.marinum_M               AG-AGGAGGDGGVGGTAGAVGSGGSGGTAGTAGTGGDGGDGGKGGATTTI
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         PGDGGIGGTGGAGGAGGAGADGDPS-IDGGQGGAGGHGGQGGKGGLNSTG
MUL_4367|M.ulcerans_Agy99           -----VGGVGCAGGAG----------------------GNGGRGDMLFT-
Mb3541|M.bovis_AF2122/97            GEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPR
Mflv_5091|M.gilvum_PYR-GCK          ------GSQGAAGKAG-------------------------ATG------
Mvan_1264|M.vanbaalenii_PYR-1       ------GSQGAAGKAG-------------------------ATG------
MMAR_5362|M.marinum_M               GSSAGSGGDGGNGGLGGAGAIGPAG----ADGSTGGQGGAGGQGGDGGDA
MSMEG_0868|M.smegmatis_MC2_155      ------GDGGAATTAG----------------------ATGGAGGFSNIA
TH_3810|M.thermoresistible__bu      ------ARAGAACASS----------------------TSRSRRSFCCSR
MAB_4284c|M.abscessus_ATCC_199      ------GGAHTSAIN-----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         LASAASGDGGNGGAGGAGGNGGAGGLG--GGGGTGGTNGNGG--------
MUL_4367|M.ulcerans_Agy99           ----------VGGSGGTGGDGGGGGSA--SGSGTGGSGGTGG--------
Mb3541|M.bovis_AF2122/97            VGGSG-GDGGTGGSGGAAGNGGNGGNAGAGGNGNGGTGGAGG--------
Mflv_5091|M.gilvum_PYR-GCK          ----------TTGATGAAGEDGDAGSG--GSGINGGAGGAGG--------
Mvan_1264|M.vanbaalenii_PYR-1       ----------TTGATGAAGDAGDPGSE--AVDINGGAGGAGG--------
MMAR_5362|M.marinum_M               VAGATNGLGGNGGDGGSGGQGGAGGVDDGGGAGTGGQGGEGGQAGDGGVS
MSMEG_0868|M.smegmatis_MC2_155      AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVG-------S
TH_3810|M.thermoresistible__bu      A-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------ESMNSSINASHSSSMNESFGSSMGSHGAAG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -------LGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATG
MUL_4367|M.ulcerans_Agy99           -------VGGIGGDGKLG--------------------------------
Mb3541|M.bovis_AF2122/97            -------IGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGS
Mflv_5091|M.gilvum_PYR-GCK          -------AGGEGGEGGDG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------AGGEGGEGGAG--------------------------------
MMAR_5362|M.marinum_M               GSGGLFGGGGDGGHGGQGGLGGTGGDSALGTGGDGGQGGQGGTGGTGGYG
MSMEG_0868|M.smegmatis_MC2_155      KIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VGNGGNGGDGGNGGDGGNGAPGGFG------GGAGAGGLGGSGAGGGTDG
MUL_4367|M.ulcerans_Agy99           ----GFGGDGGDGGDGGFGVIGGQG------GGGGFGGLGGTGAGG-APS
Mb3541|M.bovis_AF2122/97            GGTGGDGGTGGGGGNGGTGWNGGKGDTGSG-GGAGDGGKAPAGGTGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ----GKGGAGAEGGAGGGGGAGGSG-------AGGAGGAGGSGGSGGSGG
Mvan_1264|M.vanbaalenii_PYR-1       ----GAGGDGSEGGAGGSGGAGGSG-------TGGAGGAGGSGGSGGSGG
MMAR_5362|M.marinum_M               AFEGGFGGDGGDGGTGGTGGVGQSGLPGTG-GTIGIAGVPGSLPSGSTGG
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------TGFEAQGHAQGHAS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         DDGNGGSPGTDGS---
MUL_4367|M.ulcerans_Agy99           DKGINGEPGNPG----
Mb3541|M.bovis_AF2122/97            DGGAGGKGGSGGV---
Mflv_5091|M.gilvum_PYR-GCK          SGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1       AGGSGGAAGDSD----
MMAR_5362|M.marinum_M               AGGDGGDGGDGGPGSP
MSMEG_0868|M.smegmatis_MC2_155      ADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ----------------
MAB_4284c|M.abscessus_ATCC_199      ETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923          ----------------
MAV_4827|M.avium_104                ----------------