For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4999 (-)

annotation: PE-PGRS family protein
coordinates: 6068164 - 6072894
length: 1576

LTYVVVSPEIVAAAAGTLTRISSSVSAANAAAAASTTDLLAAGADEVSTRIAALFGVHGLEYQHISAQAA
AYHEQFIQAMQGGARSYAWAEAANAEQNLLNLINSPTQAFFGRSLIGDGANATTPGGAGGDGGLLIGNGG
NGAAGAAGQAGGAGGSGGLLGNGGNGGAGGIGGGAGGVGGNGGWLYGRGGVGGAGGMGGGTGGAGGHAWL
FGHGGTGGLGGGGGIGAGGAGGNGGLLYGHGGAGAAGGAGQAGGDGGSAGLWGRGGAGGAAGVGGSTGGS
GGNGGLLIGAGASGGAGTSGGAGGHGGWLIGDGGPGGTGGDGGGSGGSGGDAAWLFGNGGAGGAGGIGGG
TGGQGGDGGFLIGNAGSGGIGGIGATGTPGGHGGDGGNPGWLLGAAGTGGLGGAGGAAASTGTAGGVGGD
GGAGGRGGLFMHGGAGGNGGTGGAGAGGTDGGGSGGAGGAGGNGGAGGRAPLLFGRGGTGGYGGSGGSGG
HGGTGLDGNLAGLGGDGGGGGTGGDGGAPGTGGAGGARHLFSHNGRSGSTGIGGAGGSGGRGGDGAAGTD
AAANSGAIGGTGFSGGAGGAGGVGGGAGANQGAGGQGGDGGTGGTGGDGGDGAAGTDPLLAAQAGGQGGD
GGTGGTAGTGGTGSTMGTDGTAGDGGTGGAGGHGGTGADNTTVVGAGAMGAAGGQGGAGGTGGTGGAAGT
GGGGLQGAGGQGGDGGTGGTGGDGGDGAAGTDPLLAAQAGGQGGDGGTGGTAGTGGTGSTMGTDGTAGDG
GTGGAGGHGGTGADNTTVVGAGAMGAAGGQGGAGGTGGTGGAAGTGGGGLQGAGGQGGDGGTGGTGGDGG
DGAAGTDPLLAAQAGGQGGDGGTGGTAGTGGTGSTMGTDGTAGDGGTGGAGGHGGTGADNTTVVGAGAMG
AAGGQGGAGGTGGTGGAAGTGGGGLQGAGGQGGDGGTGGTGGDGGDGIDNSTDMTGKAGGDGGQGGDGGT
GGTAGTGGTGSTMGATGTGGTGGVGGSGGTGGHGGHGPLNSDPGGAGGKGGDGGTGGTGGAGIGTSGGGT
GGDGGAAGDGGTGGDGGEVGGTGGVGGAAGTGGDGGDGGTGGGDGGKGGTGGTGGTGGIGDPRVGGSGGD
GGAGGIGGVAGAGGQGGNAGAGGNGTGGDGGNGGIGGTGGVGGDAEPGAGGNGGAGGHGGTGGAAGAGGS
GSGSGADGSSGMGGTGGQGGDGGAGSTGANAANGSGATGKAGFAGGKGGGGGDGGAGIGGVGGGDGGNGG
SGGLGGDGGNGGSGGTNQTGGKGGAGGTGGDGGAAGAGGAGGGANGSGGTGGTGGTGGDGGKGGTVTGNG
KAGTTGGAGGAGGAGGAGGDGIGSTGGGTGGVGGNAGDGGDGGNGSNGGNGNSDGGTGGTGGAAGAGGTG
GVGGSGGGDGGAAGAGGTGGNGGKGGNARLNGNGDGGMGGQGGAAGTGGIGGAAGAGGNGNGGAGGTGGV
GGGGGDGGTGGSSGKGGDGGTGGTGAVGGMGGAGGSGTGTGTGGTGGDGGDGGDGGDGGGGDGGAIPGTG
GGDGGSGDTGNLPVGVTGGTGGTGGTAGTAGAGGLT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4999--100% (1576)PE-PGRS family protein
M. marinum MMMAR_1594-0.053.85% (1872) PE-PGRS family protein
M. marinum MMMAR_4316-0.049.26% (1831) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.058.93% (1690) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.048.48% (858) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.050.03% (1907) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1238.04% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-5332.12% (551) hypothetical protein MAB_4284c
M. avium 104MAV_4827-8e-2644.75% (181) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-16741.40% (1058) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-4641.70% (283) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.047.90% (1142) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.048.82% (850) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4999|M.marinum_M               --------------------------------MTYVVVSPEIVAAAAG--
Mb3541|M.bovis_AF2122/97            --------------------------------MSFVLISPEVVSAAAG--
Rv3508|M.tuberculosis_H37Rv         --------------------------------MSFVLIAPEFVTAAAG--
MUL_4367|M.ulcerans_Agy99           --------------------------------MSFVSVGPGLLEAAAR--
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               TLTRISSSVSAANAAAAASTTDLLA-----AGADEVSTRIAALFGVHGLE
Mb3541|M.bovis_AF2122/97            DLANVGSTISAANKAAAAATTQVLA-----AGADEVSARIAALFGMYGLE
Rv3508|M.tuberculosis_H37Rv         DLTNLGSSISAANASAASATTQVLA-----AGADEVSARIAALFGGFGLE
MUL_4367|M.ulcerans_Agy99           DLAGLGAGLREANLAAAGATVGVLP-----AAGDEVSAAIAELFGGFGRE
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------MVTFGGGA--
Mvan_1264|M.vanbaalenii_PYR-1       ----MMFLAPPGGPGPISAAIQLTS-----TGSEATEPWYVVSFGGSG--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -MSIIDFILNLFRDPVEAASYVADP------EAALANAGLSAVSAAQVGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA
                                                                                      

MMAR_4999|M.marinum_M               YQHISAQAAAYHEQFIQAMQGGARSYAWAEAAN------AEQNLLNLINS
Mb3541|M.bovis_AF2122/97            YQAISAQVAAYHQQFVQTLRTGAASYMLAEATN------VEQNLLNLINA
Rv3508|M.tuberculosis_H37Rv         YQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA
MUL_4367|M.ulcerans_Agy99           YQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNA
Mflv_5091|M.gilvum_PYR-GCK          -TPTPTSLGAAAVDLSGTSCG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -APTPNNLAASLVDLSGTSCG-----------------------------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VMPVVAESVASNYGYQSQWVN-----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TASAPDRVISAILGTREG--------------------------------
                                                                                      

MMAR_4999|M.marinum_M               PTQ-----------------------------------------------
Mb3541|M.bovis_AF2122/97            PTQ-----------------------------------------------
Rv3508|M.tuberculosis_H37Rv         PTQ-----------------------------------------------
MUL_4367|M.ulcerans_Agy99           PSM-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ----------------------------------AFFGRSLIGDGAN-AT
Mb3541|M.bovis_AF2122/97            ----------------------------------TLLGRPLIGDGAN-AT
Rv3508|M.tuberculosis_H37Rv         ----------------------------------ALLGRPLIGDGAN-AT
MUL_4367|M.ulcerans_Agy99           ----------------------------------ALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQD---
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               TPGGAGGDGGLLIGNGGNGA-AGAAGQAGGAGGSGGLLG-NGGNGGAGGI
Mb3541|M.bovis_AF2122/97            TPGGAGGDGGLLFGSGGNGA-PGAPGQAGGAGGSAGLLG-NGGSGGAGGT
Rv3508|M.tuberculosis_H37Rv         TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWG-NGGPGGAGGS
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIG-TGGVGGAGG-
Mflv_5091|M.gilvum_PYR-GCK          ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG--
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG--
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDND------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----AADAGLQLSSIGVTWTDQLEAAALRDALAARRID-----------
                                                                                      

MMAR_4999|M.marinum_M               GGGAGGVGGNGGWLYGRGGVGGAGGMGGGTGGAGG-HAWLFGHGGTGGLG
Mb3541|M.bovis_AF2122/97            G-APGGNGGNAGWLYGRGGVGGAGGIGGGTGGAGG-HAWLFGHGGTGGIG
Rv3508|M.tuberculosis_H37Rv         GGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVG
MUL_4367|M.ulcerans_Agy99           ----------------VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAA
Mflv_5091|M.gilvum_PYR-GCK          -------------------------LGGGNGGNGG-NAGAFALFGNG---
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------LGSGDGGNGG-DAGLFSLFGRG---
MSMEG_0868|M.smegmatis_MC2_155      G------------------------LDGGNGGSGGLLMGIGGAGGAGGVG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------FLSHNDTDFASHNPIASGN-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------NVMLVSAFLAAAALAQNVGGAMG-----
                                                                                      

MMAR_4999|M.marinum_M               GGGGIGAGGAGGNGGLLYGHGGAGAAGGAGQAGGDGGSAGLWGRGGAGGA
Mb3541|M.bovis_AF2122/97            GG-------PGGNGGWLLGNGGHGGAGGIG--------------------
Rv3508|M.tuberculosis_H37Rv         GAGGG-TGGAGGRAELLFGAGGAGGAGTDG--------------------
MUL_4367|M.ulcerans_Agy99           GAGG----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               AGVGGSTGGSGGNGGLLIGAGASGGAGTSGGAGGHGGWLIGDGGPGGTG-
Mb3541|M.bovis_AF2122/97            --------------------------GGSGGAGGNGGWLLGNGGIGGAG-
Rv3508|M.tuberculosis_H37Rv         ------------------GPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQ
MUL_4367|M.ulcerans_Agy99           -------------------------------SGGSGGWLWG---------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------ADGTSAHVDG---------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GDGGGSGGSGGDAAWLFGNGGAGGAGGIGGGTGGQGGDGG--FLIGNAGS
Mb3541|M.bovis_AF2122/97            GTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGG--WLLGNGGN
Rv3508|M.tuberculosis_H37Rv         GGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQ
MUL_4367|M.ulcerans_Agy99           -----------------NAGQTAGAG-----------------VGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------------------GNGGN
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------------------GNGGN
MSMEG_0868|M.smegmatis_MC2_155      -----------------GTGGTGGTG------------------GGTGGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------QVMSPS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------------YERT
                                                                                      

MMAR_4999|M.marinum_M               GGIGGIGATGTPGGHGGDGGNPGWLLGAAGTGGLGGAGGAAASTGTAGGV
Mb3541|M.bovis_AF2122/97            GGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGT
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGDGVLGGVGGTGGK-GGVGGVAGLGGAGGAAGQLFSAGGAAGA
MUL_4367|M.ulcerans_Agy99           GGAGDAGDQGVSG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGVGVVGATGAVG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGVGIAGATGAVG-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGIGGTGG-GLFGLLG----------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNVDSFNRGPLLDLSFG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AVLLVEPDTATLAVVETS--------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GGDGGAGGRGGLFMHGGAGGN--GGTGGAGAGGTDGGGSGGAGGAGGNGG
Mb3541|M.bovis_AF2122/97            GGDGGTGGRGGLLMGAGAGGH--GGTGGAGGAGVDGGGAGGAGGAGGNGG
Rv3508|M.tuberculosis_H37Rv         VGVGGTGGQGGAGGAGAAGADAPASTGLTGGTGFAGG-AGGVGGQGGNAI
MUL_4367|M.ulcerans_Agy99           -----------------------VAPGEAGAVGFAGG-AGGAGGAGGNGV
Mflv_5091|M.gilvum_PYR-GCK          ------------------------APGVAGATGATGVTSGVVGGNGEDAV
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------APGVAGATGATGVTSNVTGGNGADAV
MSMEG_0868|M.smegmatis_MC2_155      ------------------------HSGSTGAAGAAGNGGDGGNGGFGYVL
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------DLQFGNRDTTAIGDGAVAVGGSNSGPI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------DGSIPDVYKQQIRAESYGDAAGQLSAM
                                                                                      

MMAR_4999|M.marinum_M               AGGRAPLLFGRGGTGGYGGSGGSGGHGGTGLDGNLAGLGGDGGGGGTGGD
Mb3541|M.bovis_AF2122/97            AGGQAALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGTGGD
Rv3508|M.tuberculosis_H37Rv         AGG----INGSGGAGGTGGQGGAGGMGGSGADN-ASGIGADGGAGGTGGN
MUL_4367|M.ulcerans_Agy99           GGG----VNGAGGAGGAGGVGGGGGAGASGVG-----AGVAGGDGGTGGA
Mflv_5091|M.gilvum_PYR-GCK          GYG------ATGAAGAAGAAGAAGAAGAVGSAG----AAGEAGETGTWGN
Mvan_1264|M.vanbaalenii_PYR-1       GYG------ATGAAGAAGAAGAAGKAGAVGSAG----TAGSAGAPGVWGN
MSMEG_0868|M.smegmatis_MC2_155      IAG----PNVTVGSETRGGTGGAGGTGGQSTAA-----GPGKGGGGGGGG
TH_3810|M.thermoresistible__bu      -------------------VDGDGGSG-----------------------
MAB_4284c|M.abscessus_ATCC_199      ASG-------QGSTAVNGDVRDSNIINADHGSN----VGVDQSQTRVGGD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VAG------LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEP
                                                                                      

MMAR_4999|M.marinum_M               GGAPGTGGAGGARHLFSHNGRSGSTGIGGAGGSGGRGGDGAAGTDAAANS
Mb3541|M.bovis_AF2122/97            GGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNGGAGSAGADAPAGS
Rv3508|M.tuberculosis_H37Rv         AGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDATA-T
MUL_4367|M.ulcerans_Agy99           GGAAGVGGAAGTGGTG------GAAGVAGTGGDGGDGGAGGAGSDASL-A
Mflv_5091|M.gilvum_PYR-GCK          AGLPGKAGDAGGAGAVGAAGAAGTVGTAGATGGTGTGANGGAGG-----V
Mvan_1264|M.vanbaalenii_PYR-1       AGLPGAAGAAGGAGAIGTAGVAGAAGTAGATGGTGVGGNGGAGQ-----A
MSMEG_0868|M.smegmatis_MC2_155      GGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGR---VIA
TH_3810|M.thermoresistible__bu      ----------------------GRTGLFSKLSRGGDGGDG----------
MAB_4284c|M.abscessus_ATCC_199      YTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGS------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVD
                                                                                      

MMAR_4999|M.marinum_M               GAIGGTGFSGGAGGAGGVGGGAGANQGAGGQGGDGGTGGTGGDGGDGAAG
Mb3541|M.bovis_AF2122/97            GAMGSTGFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGTGGAGMNS
Rv3508|M.tuberculosis_H37Rv         GATGGTGFSGGAGGAGGAGGNTGVG-GTNGSGGQGGTGGAGGAGGAGGVG
MUL_4367|M.ulcerans_Agy99           GQAG---FAGGSGGAGGVGGSAGAG-GVNGSGGDGGAGAAGGAGGASAT-
Mflv_5091|M.gilvum_PYR-GCK          GGVGGTGAAGAAGGAGGLG-ETGTTGGAGGVGGQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1       GGIGGTGAAGAAGQAGTAG-ETGVTGGVGGIGGQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155      EGTGSTAEGTATGGDGGHSTGTGIG-GNGGIGSVYAYGNNGAVSGTATGG
TH_3810|M.thermoresistible__bu      --------------------------GLGGNGGHG--GGTGIISLLSLAG
MAB_4284c|M.abscessus_ATCC_199      --GNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAV
                                                                                      

MMAR_4999|M.marinum_M               -TDPLLAAQAGGQGGDGGTGGTAGTGG---TGSTMGTDGTAGDGGTGGAG
Mb3541|M.bovis_AF2122/97            -LDPLLAAQDGGQGGTGGTGGNAGAGG---TGFTQGADGNAGNGGDGGVG
Rv3508|M.tuberculosis_H37Rv         ADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAG
MUL_4367|M.ulcerans_Agy99           ------VAGSGGVGGDGGAGGAAG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------STGAVGGVGGKGIQG---------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------ATGGAGGVGGKGIQG---------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------RGGDGIDGGTGGAGGMGEIYS-----------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VG------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GHGGTGADN-TTVVGAGAMGAAGGQGGAGGTGGTGGAAGTGGG-GLQGAG
Mb3541|M.bovis_AF2122/97            GNGGNGADN-TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTG-GQQGNG
Rv3508|M.tuberculosis_H37Rv         GAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNA
MUL_4367|M.ulcerans_Agy99           --------------------------------------------GGVGAA
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------------GQG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------------GQG
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------GADGEATGISAGGDGGSATGAD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------ISAVLALEIA
                                                                                      

MMAR_4999|M.marinum_M               GQGGDGGTGGTGGDGGDGAAG-TDPLLAAQAGGQGGDGGTGGTAGTGGTG
Mb3541|M.bovis_AF2122/97            GNGGNGGTGGKGGTGGAGMNS-LDPLLAAQDGGQGGTGGTGGNAGAGGTG
Rv3508|M.tuberculosis_H37Rv         GIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVG
MUL_4367|M.ulcerans_Agy99           SLGGDGGHAGAGGAGGEGLSGGFNTGAAGGIGGAGGAGGTGGDSG--GVG
Mflv_5091|M.gilvum_PYR-GCK          LQGGKGGDGGAGGKGGD----------ADSMGSAGATGGKGGNGGNGGRG
Mvan_1264|M.vanbaalenii_PYR-1       LQGGQGGDGGTGGTGGD----------ATSMGEAGATGGKGGNGGNGGRG
MSMEG_0868|M.smegmatis_MC2_155      SLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVM
TH_3810|M.thermoresistible__bu      -NGGNGGNG------------------YRTTDNNALDGGHGGNGGNVGFF
MAB_4284c|M.abscessus_ATCC_199      -NAGLAGNAGLAGNAG-----------LAGNAGLAGNAGLAGNAGLAGNA
MLBr_01183|M.leprae_Br4923          ---------------------------MPLFLNAEPQALTAAANTLEGLS
MAV_4827|M.avium_104                LAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVA
                                                                         .            

MMAR_4999|M.marinum_M               STMGTDGTAGDGGTGGAGGHGGTGADNTTVVGAGAMGAAGGQGGAGGTGG
Mb3541|M.bovis_AF2122/97            FTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGG
Rv3508|M.tuberculosis_H37Rv         GTNGSGGAGGAGGKGGTGGAGGSGAD--NPTGAGFAGGAGGTGGAAGAGG
MUL_4367|M.ulcerans_Agy99           GVNGDGGAGGGGGRGGDGGSSTS------TSGVGGAGGAGGNGGNAGFGV
Mflv_5091|M.gilvum_PYR-GCK          GLFGKGGNAGNGADGGTGGAGGA-------------GGTGGTGGAGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       SLFGRGGNAGNGGNGGTGGNGGN-------------GGTGGTGGNGGTGG
MSMEG_0868|M.smegmatis_MC2_155      AAGATGVATGNTAIGGNGGAASAN------------GAVGGNGGFTNIAA
TH_3810|M.thermoresistible__bu      SLFNLGGAGGWGGSGVDG-----------------VDVVGGNPDGGTPG-
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAGLAGNAGLAGN-------------AGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923          AATVASNAAAAQLT----------------------------TEIAPP--
MAV_4827|M.avium_104                APKPLSPPVAAPLPAAPPPAAPP------------LPEAPPIPAAPPVVP
                                             .                                        

MMAR_4999|M.marinum_M               TGGAAGTGG-GGLQGAGGQGGDGGTGGTGGDGGDGAAGTDPLLAAQAGGQ
Mb3541|M.bovis_AF2122/97            TGGAAGTGT-GGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQ
Rv3508|M.tuberculosis_H37Rv         AGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQ
MUL_4367|M.ulcerans_Agy99           SAGGTG-----------GSAGDGGAGG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          TG---------------GTGGIGGAGSTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       TG---------------GTGGIGGAGSTG---------------------
MSMEG_0868|M.smegmatis_MC2_155      IHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN-------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGN----------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPVVVP--------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GGDGGTGGTAGTGGTGSTMG--TDGTAGDGGTGGAGGHGGTGADNTTVVG
Mb3541|M.bovis_AF2122/97            GGTGGTGGNAGAGGTGFTQG--ADGNAGNGGDGGVGGNGGNGADNTTTAA
Rv3508|M.tuberculosis_H37Rv         GGQGGAGGSAGAGGINGAGG--AGGNGGDGGDGATGA-----------AG
MUL_4367|M.ulcerans_Agy99           ----------GAGGVDGVGG--ASGNGGAAGAGGAGG-----------SG
Mflv_5091|M.gilvum_PYR-GCK          ----------GTGGTGGTGG--TGGTGGTGGTGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------GTGGTGGTGG--TGGTGGTGGTGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      ----------GPAGTTIDKGKAAGGNGGDGGFNGTGG-------------
TH_3810|M.thermoresistible__bu      -----------AHGESHTPGVYTDRQGEDGEDGTGTG-------------
MAB_4284c|M.abscessus_ATCC_199      ---------AGLAGNAGLAG--NAGLAGNAGLAGNAG-------------
MLBr_01183|M.leprae_Br4923          ----------AADDVSILLAHFFSGHGRQYQAHASQG-------------
MAV_4827|M.avium_104                -----------PVPVPVPVRIPVPDPVSPPQLLAPPR-------------
                                                                                      

MMAR_4999|M.marinum_M               AGAMGAAGGQGGAGGTGGTGGAAGTGGGGLQGAGGQGGDGGTGGTGGDGG
Mb3541|M.bovis_AF2122/97            AGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGG
Rv3508|M.tuberculosis_H37Rv         LGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGG
MUL_4367|M.ulcerans_Agy99           IG----AGIDGGAGGAGGTGGAAGF-----PGGGGTTGAWGTGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ------TGGTGGKGGTGGTGG-----------AGGTGGDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       ------TGGTGGKGGTGGTGG-----------DGGTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      -----ATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAG
TH_3810|M.thermoresistible__bu      ------IGGRGGNGGSS----------------SGTHPMAEDGEHVKALD
MAB_4284c|M.abscessus_ATCC_199      ------LAGNAAVAGNAAVAG-----------NAAVAGNAAVGGVLNTGV
MLBr_01183|M.leprae_Br4923          ------ATNHQDLIQSLLT---------------SSSAYAGTETANHDSL
MAV_4827|M.avium_104                ------LSVPQPVQPPVRVPQ--------------PPSPPQVGGTVPQSP
                                                                                      

MMAR_4999|M.marinum_M               DGIDN----------------------STDMTGKAGGDGGQGGDG-----
Mb3541|M.bovis_AF2122/97            DGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGNGGIGAA
Rv3508|M.tuberculosis_H37Rv         AGDNNFNGGQGG--AGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGA
MUL_4367|M.ulcerans_Agy99           AG------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          TG------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TG------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AN------------------------------------------------
TH_3810|M.thermoresistible__bu      GR------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SG------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PQ------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ------------GTGGTAGTGGTG---------STMGATGTGG-------
Mb3541|M.bovis_AF2122/97            GTTGPVGTGASGGTGGSGGAGGTGGDGG-AANGGTAGAGGAGGNGGKGGD
Rv3508|M.tuberculosis_H37Rv         GGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGGDGGD
MUL_4367|M.ulcerans_Agy99           ------GAGDHGGVGVNPGDSGTAG-------------------------
Mflv_5091|M.gilvum_PYR-GCK          ------------GTGGTGGTGGAG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------GTGGTGGTGGAG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------GNGGAGGAGGVSEGEG----------------------
TH_3810|M.thermoresistible__bu      -------------PGLDGGNGSHG--------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------AIGGSSHVGGAIN-------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------HQTPPGEGTPPK-------------------------
                                                                                      

MMAR_4999|M.marinum_M               ------------TGGVGGSGGTGGHGGHGPLNSDP---------------
Mb3541|M.bovis_AF2122/97            GGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGDG
Rv3508|M.tuberculosis_H37Rv         GASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAG---------------
MUL_4367|M.ulcerans_Agy99           -----------WAGGAGGAGGAGGSAAFNGVNGAG---------------
Mflv_5091|M.gilvum_PYR-GCK          -------------DGTGGTGGTGGTGGQG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------DGLGGTGGTGGTGGFG---------------------
MSMEG_0868|M.smegmatis_MC2_155      -----------GTGGHGGDGGRGGDGALGGNGGTGGVG------------
TH_3810|M.thermoresistible__bu      --------------GNGGHGGRGGFLGIG---------------------
MAB_4284c|M.abscessus_ATCC_199      -------------ESLGGSGSVGGSTAVG---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------PDGPGNYGG--------------------------
                                                                                      

MMAR_4999|M.marinum_M               ------------------GGAGGKGGDGGTGGTGGAGIG---TSGGGTGG
Mb3541|M.bovis_AF2122/97            AAGAVGISGATGAGDGGHGGTGGAGGNGGTGGAGGSGID---GVGGGTGG
Rv3508|M.tuberculosis_H37Rv         -------------------GAGGNGGDGGDGATGAAGLGD-NGGVGGDGG
MUL_4367|M.ulcerans_Agy99           -------------------GAGGNGGAGGGGGAGASGIG--AGVAGGDGG
Mflv_5091|M.gilvum_PYR-GCK          -------------------GQGGQGGTGGTGGQGGLG------GGGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------GQGGQGGTGGTGGQGGLG------GVGGTGG
MSMEG_0868|M.smegmatis_MC2_155      ------------------LGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu      -------------------GSGGWGGHGGNGGDTDAD--------GGNGG
MAB_4284c|M.abscessus_ATCC_199      ---------------------GGAHTGVGGGVSTGVG-------VGSHVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------GHVPTPGAGGSGGSGGGHVP-----------
                                                                                      

MMAR_4999|M.marinum_M               DGGAAGDGG--------TGGDGGEVGGTG---------------GVGGAA
Mb3541|M.bovis_AF2122/97            TGGNGGNGA--------IGGAGGDAGGSGNSGGNGGTGGKGGNAGAGGAA
Rv3508|M.tuberculosis_H37Rv         AGGAAGNGGNAGVGLTAKAGDGGAAGNGGN-------------GGAGGAG
MUL_4367|M.ulcerans_Agy99           TGGTGG-----------AAGTGGAAGTGGT-------------GGAAGAA
Mflv_5091|M.gilvum_PYR-GCK          QGGTGG--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGAGRIRVN--------NGTATGTATGGN--------------------
TH_3810|M.thermoresistible__bu      DG------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGISES--------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               G----------TGGDGGDG----------------GTGGGDGGKGGT-GG
Mb3541|M.bovis_AF2122/97            GSNGGTVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGR-GG
Rv3508|M.tuberculosis_H37Rv         GAGDNNFNG-GQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGK-GG
MUL_4367|M.ulcerans_Agy99           GS------------------------------------AGDGGAGGA-GG
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------TGGQGGTGGT-GG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------TGGQGGTGGT-GG
MSMEG_0868|M.smegmatis_MC2_155      -----------------------------------GGNGGNGDADGHRGG
TH_3810|M.thermoresistible__bu      ---------------------------------------GNGGSAGR---
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------LGGSGSVGGS---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------TPGAGGSGGS---
                                                                                      

MMAR_4999|M.marinum_M               TGGTGG--IG-----------DPRVGGSGGDGGAG---------GIGGVA
Mb3541|M.bovis_AF2122/97            SGGAGGDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQG
Rv3508|M.tuberculosis_H37Rv         AGGAGTLGVGGS----------GGTGGDGGDAGSG---GGGGFGGAAGKA
MUL_4367|M.ulcerans_Agy99           AGDDGSAGVVS------------------GDPG------------TAGKA
Mflv_5091|M.gilvum_PYR-GCK          TGGTGG--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      KGGDGGEALIR-----------------------------------ATVI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GAGGQGGNAGAG-----GNGTGGDGGNGGIGGTGGVGGDAEPGAGGNGGA
Mb3541|M.bovis_AF2122/97            GSGGAGGAAGAGGAGGGANGTAGNGGQGGAGGTGGAGAASSATNGGSGGA
Rv3508|M.tuberculosis_H37Rv         GGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAG-----GSAGAGGI
MUL_4367|M.ulcerans_Agy99           GGAG---------------------------GAGGVG-----GNGVAGGV
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------TGGAG-----GDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------TGGAG-----GDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155      GSNASG------------------------TATGGDGG----NGGTLGAT
TH_3810|M.thermoresistible__bu      -----------------------------------------------GGT
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------TAVGGGAH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------------GGGH
                                                                                      

MMAR_4999|M.marinum_M               GGHGGTGGAAGAGGSGSGSGADGSSGMG----------------------
Mb3541|M.bovis_AF2122/97            GGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANGNNRSSGSFLA
Rv3508|M.tuberculosis_H37Rv         NGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPG
MUL_4367|M.ulcerans_Agy99           NGSGGAGGAG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGFGGSGGTG----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGFGGVGGTG----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGTGGAATIVAYNVVQANPQASG---------------------------
TH_3810|M.thermoresistible__bu      GGLRGVFGIN----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGVGGGVSTG----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPTPGTGGPG----------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ---------------------GTGGQGGDGGAGSTGAN------------
Mb3541|M.bovis_AF2122/97            AGGTGGAAGDGGQGGQGGAGGGAGGQGGAGGAGGTGGNGGNITGGTAGTA
Rv3508|M.tuberculosis_H37Rv         DGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPS------IDGGQ
MUL_4367|M.ulcerans_Agy99           ------------------------GAGGTGGAGASGVP------------
Mflv_5091|M.gilvum_PYR-GCK          ------------------------GQGGLGGPG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------GQGGQGGPG-----------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------------TATDGHGGSGIN---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------VGVGSHVGGGIS---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               -AANGSGATGKAGFAG---------GKGGGGGDGGAG-------------
Mb3541|M.bovis_AF2122/97            GAAGNGGAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTV
Rv3508|M.tuberculosis_H37Rv         GGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGD--------
MUL_4367|M.ulcerans_Agy99           -----------------------ASVDGGDGGAGGAGG------------
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------GSTGGAGGAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------GSTGGAGGAG-------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------GGHGGNGGQGTIEAN--------
TH_3810|M.thermoresistible__bu      ------------------------------GGNGRAG-------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------ESLGGSGSVG-------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------GTGGSG-------------
                                                                                      

MMAR_4999|M.marinum_M               ---------------IGGVGGGDG-----------GNGGSGGLGGDGGNG
Mb3541|M.bovis_AF2122/97            PAGSGGQGGNAGGGGAGGQGGADG-----------GSGGDGGDAGTGGNG
Rv3508|M.tuberculosis_H37Rv         --------GDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRG
MUL_4367|M.ulcerans_Agy99           ---------------AAGTGGSG------------GSAGNTGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------GQAGTAGKGGLFGGS
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------GQAGVAGKGGLFGGS
MSMEG_0868|M.smegmatis_MC2_155      ----------------GPSAVASG----------IGAGGNGGDGIDGGLG
TH_3810|M.thermoresistible__bu      ------------------------------------LGGRGXXXXGGGVG
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------GSTAVGGGAHTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------GGHVPTPGAGTPG
                                                                                      

MMAR_4999|M.marinum_M               GSGGTN-----------------------------QTGGKGGAG------
Mb3541|M.bovis_AF2122/97            GNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNGGAGGDAGDA
Rv3508|M.tuberculosis_H37Rv         GDGGAG-----------------------------DSGALSQDGNGFAGG
MUL_4367|M.ulcerans_Agy99           GAGGSA-----------------------------ASTGVNGDG------
Mflv_5091|M.gilvum_PYR-GCK          GSAGKA--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GSAGTA--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGDG---------------------------VVNTTANAAN-------
TH_3810|M.thermoresistible__bu      AAVRS---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGGVN--------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GSGGGHLP------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               --------------------------------------------------
Mb3541|M.bovis_AF2122/97            GNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGNGGNGGSGGNGGNAGM
Rv3508|M.tuberculosis_H37Rv         QGGQGGVGGNAGAGGIN---------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               -----------GTGGDGGAAGAGGAGG--GANGSGGTGGTGGTGGDGGKG
Mb3541|M.bovis_AF2122/97            GGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLTGTGGTGGSGGTGGDGGNG
Rv3508|M.tuberculosis_H37Rv         -----------GAGGTGGTGGAGGDGQN-GTTGVASEGGAGGQGGDGGQG
MUL_4367|M.ulcerans_Agy99           -----------GAGGAGGVGGLGGDS--------AATAGGGGAGGDGGKG
Mflv_5091|M.gilvum_PYR-GCK          -------------GATGAAGASGGKG---------AQGATGAQGATGAQG
Mvan_1264|M.vanbaalenii_PYR-1       -------------GVTGASGASGGKG---------AQGATGAQGATGAQG
MSMEG_0868|M.smegmatis_MC2_155      -------------PGSATGTATGGDG--------GKATGTASQGGNGGPS
TH_3810|M.thermoresistible__bu      --------------GNGVFSGGGGTP------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------TGVGVGSHVGGGIS-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------FPGAGSTPGGSGGG------------------------
                                                                                      

MMAR_4999|M.marinum_M               GT-----------------------------VTGNGKAG----TTGGAGG
Mb3541|M.bovis_AF2122/97            GNGGNGADNTANMTAQAGGDGGNGGDGGFGGGAGAGGGG----LTAGANG
Rv3508|M.tuberculosis_H37Rv         GIGG---------------------------AGGNAGFGAGVPGDGGIGG
MUL_4367|M.ulcerans_Agy99           GAGG---------------------------AGVNGVGG----GDGGKGG
Mflv_5091|M.gilvum_PYR-GCK          ATG----------------------------------------ATGAAGK
Mvan_1264|M.vanbaalenii_PYR-1       ATG----------------------------------------ATGASGA
MSMEG_0868|M.smegmatis_MC2_155      WVQSG--------------------------YGSTLGGNATGTATAGKGG
TH_3810|M.thermoresistible__bu      --------------------------------------------SAGFGV
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------------ESLGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------HLPTPG
                                                                                      

MMAR_4999|M.marinum_M               AGGAGGAGGDG----IGSTG------GGTGGVGGNAGDG-----------
Mb3541|M.bovis_AF2122/97            TGGQGGAGGDGGNGAIGGHGPLTDDPGGNGGTGGNGGTGGTGGAGIGSLG
Rv3508|M.tuberculosis_H37Rv         TGGAGGAGGAGADGDPSIDG-------GQGGAGGHGGQGGKGGLNSTGLA
MUL_4367|M.ulcerans_Agy99           TGGAGGAGGAGSDGIIPSNG-------GLGGNGGNGGNGGQ---------
Mflv_5091|M.gilvum_PYR-GCK          AGATGAAGAAGAAGSAGTTG-------AQGSAGTNGANG-----------
Mvan_1264|M.vanbaalenii_PYR-1       QGSAGSAGSAGVAGSAGTTG-------AQGSAGTNGANG-----------
MSMEG_0868|M.smegmatis_MC2_155      EASNGGVAGNGGNALVMAAG-------TTGVATGNTATG-----------
TH_3810|M.thermoresistible__bu      PTTIQFPAGSCTSRAVSREG------------------------------
MAB_4284c|M.abscessus_ATCC_199      SGSVGGSTAVGGGAHTSAIN------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AGTPGGGLGGFGGGHAPAPG------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ----GDGGNGSNGGNGNSDG-------GTGGTGGAAGAGGTGGVGGSGG-
Mb3541|M.bovis_AF2122/97            GGTGGDGGNGGTGGNGGTGGEG-GEVGGAGGTGGAAGNGGDGGTGGTGG-
Rv3508|M.tuberculosis_H37Rv         SAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGT
MUL_4367|M.ulcerans_Agy99           --AFGDG------------------VGGAGGIGGKGGNAAIGTIVING--
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------ANGSQGAAGKAGATGTTGATG--
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------ANGSQGAAGKAGATGTTGATG--
MSMEG_0868|M.smegmatis_MC2_155      ----GDGGAATTAG-------------ATGGAGGFSNIAAIHGAITDSTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ---------------------------------------------GDGGA
Mb3541|M.bovis_AF2122/97            ---------------------------------------------GDGGA
Rv3508|M.tuberculosis_H37Rv         AGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGI
MUL_4367|M.ulcerans_Agy99           ------------------------------------------------GV
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------------A
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------------A
MSMEG_0868|M.smegmatis_MC2_155      ISG--------------------------------------------HGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               AGAGGTGGNGGKGGNARLNGNG----------------------------
Mb3541|M.bovis_AF2122/97            GGTGGTGGTGGLGDPRVGGSGG----------------------------
Rv3508|M.tuberculosis_H37Rv         NGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGF
MUL_4367|M.ulcerans_Agy99           GGAGGSGGLGGATEDG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK          AGEDGDAGSGG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGDAGDPGSEA---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AGNGGNGGKGADGWVQAYDPAG----------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               ------DGGMGGQGGAAGTG---------------------GIGGAAGAG
Mb3541|M.bovis_AF2122/97            ------DGGTGGSGGAAGNG---------------------GNGGNAGAG
Rv3508|M.tuberculosis_H37Rv         GAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLN
MUL_4367|M.ulcerans_Agy99           ---------VGGVGCAGGAG---------------------GNGGRGDML
Mflv_5091|M.gilvum_PYR-GCK          ---------SGINGGAGGAG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------VDINGGAGGAG------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----PVGSKIANSSAVAGNG---------------------GDGGVNGTG
TH_3810|M.thermoresistible__bu      ---------IMPSSRAASAR------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------DALGGSGSVG------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GNG----------NGGAGGTGGVGGGG--GDGGTGGSSGKGGDGGTGGTG
Mb3541|M.bovis_AF2122/97            GNG----------NGGTGGAGGIGGTG--GNGGDAEPGVPPGAGGAGGAG
Rv3508|M.tuberculosis_H37Rv         STGLASAASGDGGNGGAGGAGGNGGAG--GLGGGGGTGGTNGNGGLGGGG
MUL_4367|M.ulcerans_Agy99           FT-----------VGGSGGTGGDGGGG--GSASGSGTGGSGGTGGVGGIG
Mflv_5091|M.gilvum_PYR-GCK          ---------------GAGGEGGEGGDG--GKGGAGAEGGAGGGGGAGGSG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------GAGGEGGEGGAG--GAGGDGSEGGAGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155      --------------GASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG
TH_3810|M.thermoresistible__bu      ------------------------------AGAACASSTSRSRRSFCCSR
MAB_4284c|M.abscessus_ATCC_199      ---------------GSTAVGGGAHTSAINESMNSSINASHSSSMNESFG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------GGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLG
                                                                                      

MMAR_4999|M.marinum_M               AVGGMGGAGGSGTGTGTGGTGGDGGD---------------GGDGGDGGG
Mb3541|M.bovis_AF2122/97            TTGGKGGTGGNGSGTGSGGTGGDGGT---------------GGGGGNGGT
Rv3508|M.tuberculosis_H37Rv         GNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATGVGNGGNGGDGGN
MUL_4367|M.ulcerans_Agy99           GDGKLG------------------------------------GFGGDGGD
Mflv_5091|M.gilvum_PYR-GCK          AG----------------------------------------GAGGAGGS
Mvan_1264|M.vanbaalenii_PYR-1       TG----------------------------------------GAGGAGGS
MSMEG_0868|M.smegmatis_MC2_155      GDGSEP------------------------------------GPGGNGAG
TH_3810|M.thermoresistible__bu      A-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SS---------------------------------------MGSHGAAGT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGHK----------------------------------------------
                                                                                      

MMAR_4999|M.marinum_M               GDGGAIPGTGGGDGGSGDTGNLPVGVTGGTGGTGGTAGTAGAGGLT
Mb3541|M.bovis_AF2122/97            GWNGGKGDTGSG-GGAGDGGKAPAGGTGGAGGDGGAGGKGGSGGV-
Rv3508|M.tuberculosis_H37Rv         GGDGGNGAPGGFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS-
MUL_4367|M.ulcerans_Agy99           GGDGGFGVIGGQGGGGGFGGLGGTGAGG-APSDKGINGEPGNPG--
Mflv_5091|M.gilvum_PYR-GCK          GGSGGSGGSGGSGGAAGDSDD-------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGSGGSGGAGGSGGAAGDSD--------------------------
MSMEG_0868|M.smegmatis_MC2_155      GAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu      ----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GFEAQGHAQGHASETAHTTLPGAEHH--------------------
MLBr_01183|M.leprae_Br4923          ----------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------------