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M. marinum M MMAR_4316 (-)

annotation: PE-PGRS family protein
coordinates: 5307272 - 5313196
length: 1974

SFVWVSPELVSAAAADVAGIGSAVGAANTAAAAATTELLAAGGDEVSAAIAELFGMYGRDYQRIAVEAAG
FHARVAALLGAGADSYGWAESSGVLSLQGLQRDVWGMVNAPTQMLLGRPLIGDGADGGTVGGVGQSGGAG
GLLWGNGGAGGVSTNPGAVGGAGGSAGLIGAGGAGGRGGAGGGGGVGGSGGWLAGVGGAGGAGGVGAIGG
AGGSAGLFGGGGSGGAGGAGDVGVAGGAGGVGGRGGWVFGDGGSGGVGGSGGVGVVGGVGGVGGGTGVFG
GGGAGGAGGVGGGTGGSGGNGGWLIGAGGIGGDGGAGFAGLPGGFAGGDGGAGGFGGGGGLFGEGGAGGA
GGVGGAGTSGGDAVVPGGVGGVGGSGGAGGAGGSGGGAGWLGTAGDGGVGGVGGGGGGGGVGASGVGHQL
AGGAGGAGGAGGAAGAGGAAGQGRGGTVGAAGVGGTGGVGGDGGAGDSGAAASAPGGAGGTGWAGGAGGA
GGAGGAAAAGGTAGVGGAGGDGGAGGVGAEGAAGAGVVGGGAGGDGGAGGAAGAGGSGGGGIGGGKAGTG
GDGGIGGAGGTGGGGGNGDTYSTGGAGGDGGAGGAAGSAGGAGAGSGGAAGSAGSGGSGGDGGAGGASGR
ELGSNLGYAGGVGGDGGQGGQGGAAVGGLAGAAGSGGNGGAGGAGGASAVALVGGAGGAGGAGGQGGTAG
DGPGGVGGHGGSGGSGGIGGTGGDGYQSGDVGGQGGEGGAGGAAGAGGEAGAQGLAGAGGTGGTGGQGGT
GGIGAQGSNGHGVGGRPGTAGAVGGAGGAGGQGGAAGLDGTAGDGGVGGTGGRGGAGGDGAGGVGHQLAG
GAGGDGGAGGAAGVGGAAGAGSGGVVGAAGTGGTGGAGGNGGAGDTGVAASTPGDPGGVGFAGGAGGAGG
AGGASGVGGVNGVGGAGGDGGTGGAGGAGAGGDRTDGGRGGVGGAGGDAGAGGVTGAGGSGGGVGNAGVG
GAGGVGGAGGAGGAADGPGLFGYDGGAGGAGGIGGAAGVGGSNGAGGTGGAGGVGGVGADSGLASRPGGA
GGAGGTGGAGGGAGSGAGGLGAGGDGGTGGAGGAGGVGSSAGWGSGLAGQVGGAGGVGGAGGDSGGLGGT
NGDGGAGGLGGRGGAGGSSTTVAGAGGGGGRGGDGGSAGGGVGGGGVGGAAGSGGAGGAGGRGIDSYAAA
GGRGGDGGAGGIGGGGGLSGIGGAGGQGGSGGAAGTGGDVGGSPGEVGGAGGGGGFGGAGGAGGVGGGAG
GSGGVGGSGGNGGLGVATGGAGGVGGQGGAAGAGGAAGAGATAAGAGGVGGLGGDGGNGGNGVRGAAGVA
GGDGAVGGGGGAGGAGGQGGAGVTGGSAGAGGQGGNGGLGGPGGDGGSAVRYQRVGGAGGVGGVGGAAGA
GGAAGQGGGGAVGAAGVGGTGGVGGNGGAGDAGVAGADGGGAGGSGWAGGAGGAGGQGGAANGGVAGDGG
VGGNGGVGGVGGRGGDGANGAPGGGIDGTGRPGGAGGQGGSGGRAGFGGAAGAGEGGEYGAAGVGGNGGD
GGAGGRGGYGTTGSGGLFGGSGGHGGVGGIGGNGGSAAAGGVNGNGGNGGIGGNAGDAGNGANGSLLHHA
GDGGNGGRGGAGGAGGFAGDGEGSGGTAGSGGNGGKGGNAGAGGNGVPAAGAAAGNGGLGGSGGAGGSGA
IGAAAGGAGGAGGNGGTGGNAGIGVMRGASTPALAGDGGVGGAGGLGGVARSVGGVGGVGGDGGSGGTGG
IGTTGNSATNGYGGAGGAGGAGGVGGNGGFAALGTGGAAGSGGGGGTGGAGGVSDSPTTSRSVGGAGGVG
GVGGNGGIGGNGQIGGDGGSGGAAGAGGAGAQNLTRSIQSANFGGAGGAGGVGGFGGVGGTGASGLGGSG
GIGGDGGAGGVGGDCSVPLSPGNGGDGGAGGDGGDGGDGGNGQPGGPGGAGGGAASGGAGGYGQLGNGAA
GADGNNGTPGADG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4316--100% (1974)PE-PGRS family protein
M. marinum MMMAR_5294-0.052.86% (2274) PE-PGRS family protein
M. marinum MMMAR_1594-0.050.13% (2248) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.051.63% (1999) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.050.88% (792) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.051.17% (1966) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB5e-1044.68% (94) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4284c-9e-5934.14% (577) hypothetical protein MAB_4284c
M. avium 104MAV_4827-3e-2542.53% (174) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17241.17% (1093) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-3e-4540.64% (342) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.053.10% (1130) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.049.94% (791) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               --------------------------------MSFVWVSPELVSAAAAD-
MUL_4367|M.ulcerans_Agy99           --------------------------------MSFVSVGPGLLEAAARD-
Rv3508|M.tuberculosis_H37Rv         --------------------------------MSFVLIAPEFVTAAAGD-
Mb3541|M.bovis_AF2122/97            --------------------------------MSFVLISPEVVSAAAGD-
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104                -----------------------------MNIVLGVSMAPSSIQMVVLEG
MLBr_01556|M.leprae_Br4923          ------------------------------MAGKARVHELAKELGVTSKE
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------MVTFGGGA-------
Mvan_1264|M.vanbaalenii_PYR-1       ----MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSG-------
MMAR_4316|M.marinum_M               -VAGIGSAVGAANTAAAAATTELLAAGGDEVSAAIAELFGMYGRDYQR--
MUL_4367|M.ulcerans_Agy99           -LAGLGAGLREANLAAAGATVGVLPAAGDEVSAAIAELFGGFGREYQA--
Rv3508|M.tuberculosis_H37Rv         -LTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQA--
Mb3541|M.bovis_AF2122/97            -LANVGSTISAANKAAAAATTQVLAAGADEVSARIAALFGMYGLEYQA--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104                EYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLS-
MLBr_01556|M.leprae_Br4923          VLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQ
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----TPTPTSLGAAAVDLSGTSCG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----APTPNNLAASLVDLSGTSCG--------------------------
MMAR_4316|M.marinum_M               ---IAVEAAGFHARVAALLGAGADSYGWAESSGVLSLQGLQRDVWGMVNA
MUL_4367|M.ulcerans_Agy99           ---MGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNA
Rv3508|M.tuberculosis_H37Rv         ---ISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQIVLGVINA
Mb3541|M.bovis_AF2122/97            ---ISAQVAAYHQQFVQTLRTGAASYMLAEATN------VEQNLLNLINA
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      TGNPIHDLSGNLQNYYAAQPDGPS--------------------------
MAV_4827|M.avium_104                ----SIGVTWTDQLEAAALRDALAARRIDN--------------------
MLBr_01556|M.leprae_Br4923          AKRLGESLDQTLDRALDKAVAGNGATTAAP--------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               PTQ-----------------------------------------------
MUL_4367|M.ulcerans_Agy99           PSM-----------------------------------------------
Rv3508|M.tuberculosis_H37Rv         PTQ-----------------------------------------------
Mb3541|M.bovis_AF2122/97            PTQ-----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQDG--
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQDG--
MMAR_4316|M.marinum_M               ----------------------------------MLLGRPLIGDGADGGT
MUL_4367|M.ulcerans_Agy99           ----------------------------------ALFGRPSIGNGVDG--
Rv3508|M.tuberculosis_H37Rv         ----------------------------------ALLGRPLIGDGANATT
Mb3541|M.bovis_AF2122/97            ----------------------------------TLLGRPLIGDGANATT
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------ILSPSLLSPRDNDFL
MAV_4827|M.avium_104                ----------------------------------VMLVSAFLAAAALAQN
MLBr_01556|M.leprae_Br4923          --------------------------------------VQVDHSAAVVPI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---TG---QNGGILFGNGGSG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---TG---QNGGILFGNGGSG-----------------------------
MMAR_4316|M.marinum_M               VGGVGQSGGAGGLLWGNGGAGGVSTNPGAVGGAGGSAGLIGAGGAGGRGG
MUL_4367|M.ulcerans_Agy99           VAGTGQAGGAGGILWGNGGNG-----------------------------
Rv3508|M.tuberculosis_H37Rv         PGGAG---GAGGLLFGNGGAG-----------------------------
Mb3541|M.bovis_AF2122/97            PGGAG---GDGGLLFGSGGNGAPG-APGQAGGAGGSAGLLGNGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155      DNPNG---GTGGLLFGDGGHG-----------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SHNDTDFASHNPIASGNQVMS-----------------------------
MAV_4827|M.avium_104                VGGAMGYERTAVLLVEPDTAT-----------------------------
MLBr_01556|M.leprae_Br4923          VAGEGPSTAHREELAPPAGQP-----------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------WNSDVVG-MDGGNGGNGGLFGGNGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------WNSEIAG-VSGGNGGNAGLFGGNGGNGGNG
MMAR_4316|M.marinum_M               AGGGGGVGGSGGWLAGVGGAGGAGGVG-AIGGAGGSAGLFG-GGGSGGAG
MUL_4367|M.ulcerans_Agy99           ---------------------GLGAAG-ANGGAGGSAGLIG-TGGVGGAG
Rv3508|M.tuberculosis_H37Rv         ---------------------AAGAPG-QAGGPGGPAGLWG-NGGPGGAG
Mb3541|M.bovis_AF2122/97            TGAPGGNGGNAGWLYGRGGVGGAGGIGGGTGGAGGHAWLFG-HGGTGGIG
MSMEG_0868|M.smegmatis_MC2_155      --------------------YDGSAAG-LAGGNGGNAGLFG-NGGNGGVG
TH_3810|M.thermoresistible__bu      ------------------------VDG--DGGSGGRTGLFS-KLSRGGDG
MAB_4284c|M.abscessus_ATCC_199      ------------------------PSG--NVDSFNRGPLLDLSFGDLQFG
MAV_4827|M.avium_104                -------------------------LAVVETSDGSIPDVYKQQIRAESYG
MLBr_01556|M.leprae_Br4923          ----------------------SEQPGVPLPGQQGTPAAPHPGHPGMPTG
                                                              .    .  .              *

Mflv_5091|M.gilvum_PYR-GCK          ---------------------LGGGNGGNGGNAG-AFALFGNGG------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------LGSGDGGNGGDAG-LFSLFGRGG------
MMAR_4316|M.marinum_M               ---------------GAGDVGVAGGAGGVGGRGGWVFGDGGSGGVGGSGG
MUL_4367|M.ulcerans_Agy99           ---------------GVGAAGMTGGSGGAGGGGGWLWGAGGSGGAAG---
Rv3508|M.tuberculosis_H37Rv         ---------------GSG-----GGTGGAGGAGGWLFGVGGAGGVGGAGG
Mb3541|M.bovis_AF2122/97            GGPGGNGGWLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAGGTGG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------WAGLDGGNGGSGGLLMGIGGAGGAGG---
TH_3810|M.thermoresistible__bu      ------------------------GDGGLGGNGG----------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------NRDTTAIGDGAVAVGGSNSGPIAS---
MAV_4827|M.avium_104                -----------------------DAAGQLSAMVAGLEKLESLPG------
MLBr_01556|M.leprae_Br4923          -----------------------PHPGPAPKPGGRPPRVGNNPFSSAQSV
                                                                     .                

Mflv_5091|M.gilvum_PYR-GCK          -------------------------------NGGNGGVG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------NGGNGGVG-----------
MMAR_4316|M.marinum_M               VGVVGGVGGVGGGTGVFGGGGAGGAGGVGGGTGGSGGNGGWLIGAGGIGG
MUL_4367|M.ulcerans_Agy99           -------------------------------AGGSGGSGGWLWGN-----
Rv3508|M.tuberculosis_H37Rv         ----GTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAGG
Mb3541|M.bovis_AF2122/97            ----GAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGGWLLGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------VGADGTSAH----------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          AR------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------VVGATGA
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------IAGATGA
MMAR_4316|M.marinum_M               DGGAGFAGL-------------------------------PGGFAGGDGG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------AGQTAG
Rv3508|M.tuberculosis_H37Rv         AGTDG-----------------------------------GPGATGGTGG
Mb3541|M.bovis_AF2122/97            LGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGTGG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------VDGGTGG
TH_3810|M.thermoresistible__bu      -------------------------------------------HGGGTGI
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------GQGSTAV
MAV_4827|M.avium_104                ----------------------------------------GLLLVGSGVD
MLBr_01556|M.leprae_Br4923          ------------------------------------------PIPRPPAP
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          VGAPG-------VAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1       VGAPG-------VAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAG
MMAR_4316|M.marinum_M               AGGFGGGGGLFGEGGAGGAGGVGG--AGTSGGDAVVPGGVGGVGGSGGAG
MUL_4367|M.ulcerans_Agy99           AG----------VGGAGGAGGAGD--AGDQGVSGVAPGEAGAVGFAGGAG
Rv3508|M.tuberculosis_H37Rv         HGGVGGDGGWLAPGGAGGAGGQGG--AGGAGSDGGALGGTGGTGGTGGAG
Mb3541|M.bovis_AF2122/97            DGGTGGRGGLLMGAGAGGHGGTGG--AGGAGVDG---GGAGGAGGAGGNG
MSMEG_0868|M.smegmatis_MC2_155      TGGTGGG-----TGGTGGIGGTGGGLFGLLGHSG-STGAAGAAG-NGGDG
TH_3810|M.thermoresistible__bu      ISLLS-------LAGNGGNGGNGY-------------RTTDNNALDGGHG
MAB_4284c|M.abscessus_ATCC_199      NGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVD
MAV_4827|M.avium_104                VAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYA
MLBr_01556|M.leprae_Br4923          RPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGG
                                                  .                                   

Mflv_5091|M.gilvum_PYR-GCK          AAGAAG------AVGSAGAAGEAGETGTWGNAGLPGKAGDAGG-AGAVGA
Mvan_1264|M.vanbaalenii_PYR-1       AAGKAG------AVGSAGTAGSAGAPGVWGNAGLPGAAGAAGG-AGAIGT
MMAR_4316|M.marinum_M               GAGGSGGGAGWLGTAGDGGVGGVGGGGGGGGVGASGVGHQLAG--GAGGA
MUL_4367|M.ulcerans_Agy99           GAGGAGGNGVGGGVNGAGGAGGAGGVGGGGGAGASGVGAGVAG--GDGGT
Rv3508|M.tuberculosis_H37Rv         GAGGRG--ALLLGAGGQGGLGGAGGQGGTGGAGGDGVLGGVGGTGGKGGV
Mb3541|M.bovis_AF2122/97            GAGGQA--ALLFGRGGTGGAGGYGGDGGGGGDGFDGTMAGLGGTGGSGGT
MSMEG_0868|M.smegmatis_MC2_155      GNGGFG-YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGG
TH_3810|M.thermoresistible__bu      GNGGNV------GFFSLFNLGGAGGWGGSGVDGVDVVGGNPDG--GTPGA
MAB_4284c|M.abscessus_ATCC_199      DHSQRN----TTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTSTSA
MAV_4827|M.avium_104                QDPGTG----AVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVV
MLBr_01556|M.leprae_Br4923          NYRGGG-----VGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGR
                                                                 .                    

Mflv_5091|M.gilvum_PYR-GCK          AGAAGTVGTA------------GATGGTGTGANGGAGGVG---GVGGTGA
Mvan_1264|M.vanbaalenii_PYR-1       AGVAGAAGTA------------GATGGTGVGGNGGAGQAG---GIGGTGA
MMAR_4316|M.marinum_M               GGAGGAAGAG--GAAGQGR--GGTVGAAGVGGTGGVGGDG---GAGDSGA
MUL_4367|M.ulcerans_Agy99           GGAGGAAGVG--GAAGTG----GTGGAAGVAGTGGDGGDG---GAGGAGS
Rv3508|M.tuberculosis_H37Rv         GGVAGLGGAG--GAAGQLFSAGGAAGAVGVGGTGGQGGAG---GAGAAGA
Mb3541|M.bovis_AF2122/97            GGDGGAPGNGGAGGAGQLLSHSGVAGASGKGGAGGTGGNG---GAGSAGA
MSMEG_0868|M.smegmatis_MC2_155      GGGAILIGAN-----------GGTVDGHAIGGNGGNGGNGSTTAAGGNGG
TH_3810|M.thermoresistible__bu      HGESHTPGVY-----------------TDRQGEDGEDGTG----------
MAB_4284c|M.abscessus_ATCC_199      GGSAAVGGNAG------------LAGNAGLAGNAGLAGNAG---------
MAV_4827|M.avium_104                IEKLFLPEDS------------EPRRRPVLLVGSGLAVVG----------
MLBr_01556|M.leprae_Br4923          PGGAPRRGRKS-----------KRQKRQEYDSMQAPVVGGVRLPHGNGET
                                                                      .    .          

Mflv_5091|M.gilvum_PYR-GCK          AGAAG--GAGGLGETGTTGGAGGVGGQGTAG---GTGGVGGIGGAGSTGA
Mvan_1264|M.vanbaalenii_PYR-1       AGAAG--QAGTAGETGVTGGVGGIGGQGTEG---GTGGVGGVGGVGATGG
MMAR_4316|M.marinum_M               AASAP-GGAGGTGWAGGAGGAGGAGGAAAAGGTAGVGGAGGDGGAGGVGA
MUL_4367|M.ulcerans_Agy99           DASLA-GQAG---FAGGSGGAGGVGGSAGAG---GVNGSGGDGGAGAAGG
Rv3508|M.tuberculosis_H37Rv         DAPASTGLTGGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGG
Mb3541|M.bovis_AF2122/97            DAPAGSGAMGSTGFAGGAGGDGGNGGGSGAS--QGNGGNGGNGGTGGKGG
MSMEG_0868|M.smegmatis_MC2_155      TGGTGRVIAEGTGSTAEGTATGGDGGHSTGT---GIGGNGGIGSVYAYGN
TH_3810|M.thermoresistible__bu      ---------------TGIGGRGGNGGSSSGT------HPMAEDGEHVKAL
MAB_4284c|M.abscessus_ATCC_199      -------LAGNAGLAGNAGLAGNAGLAGNAG----LAGNAGLAGNAGLAG
MAV_4827|M.avium_104                ---ISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQAS
MLBr_01556|M.leprae_Br4923          IRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGS
                                                         .                  .       . 

Mflv_5091|M.gilvum_PYR-GCK          VGG-----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGG-----------------------------------------------
MMAR_4316|M.marinum_M               EGAAGAGVVGGGAGGDGGAGGAAGAGGSGGGGIGGGKAGTGGDGGIGGAG
MUL_4367|M.ulcerans_Agy99           AGGASATVAG----------------------------------------
Rv3508|M.tuberculosis_H37Rv         MGGSGADNASG-------------IGADGGAGGTGGNAGAGGAGGAAGTG
Mb3541|M.bovis_AF2122/97            TGGAGMNSLDP--------------LLAAQDGGQGGTGGTGGNAGAGGTG
MSMEG_0868|M.smegmatis_MC2_155      NGAVSGTATGG---------------------------------------
TH_3810|M.thermoresistible__bu      DGR-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NAG-----------------------------------------------
MAV_4827|M.avium_104                APQPKISVPEP---------------------------------------
MLBr_01556|M.leprae_Br4923          EMNYNVQVVSP---------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------------VGGKGIQGGQGLQGG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------VGGKGIQGGQGLQGG----------------------
MMAR_4316|M.marinum_M               GTGGGGGNGDTYSTGGAGGDGGAGGAAGSAGGAGAGSGGAAGSAGSGGSG
MUL_4367|M.ulcerans_Agy99           -------------SGGVGGDGGAGGAAG--GGVGAAS-------------
Rv3508|M.tuberculosis_H37Rv         GTGGVVGAAGKAGIGGTGGQGGAGGAGS-AGTDATATGATGGTGFSGGAG
Mb3541|M.bovis_AF2122/97            FTQGADGNAGNGGDGGVGGNGGNG-ADNTTTAAAGTTGGAGGAGGAGGTG
MSMEG_0868|M.smegmatis_MC2_155      -------------RGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGG
TH_3810|M.thermoresistible__bu      ----------------PGLDGGNGSHGG----------------------
MAB_4284c|M.abscessus_ATCC_199      ------------LAGNAGLAGNAGLAGN----------------------
MAV_4827|M.avium_104                ------------VAAPKPLSPPVAAPLP----------------------
MLBr_01556|M.leprae_Br4923          --------EDEDRELLEPFDLTYGEDQGDEDELQVRPP------------
                                                           .                          

Mflv_5091|M.gilvum_PYR-GCK          ----------------------KGGDGGAGGKGGD----ADSMGSAGATG
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------QGGDGGTGGTGGD----ATSMGEAGATG
MMAR_4316|M.marinum_M               GDGGAGGASGRELGSNLGYAGGVGGDGGQGGQGGAAVGGLAGAAGSGGNG
MUL_4367|M.ulcerans_Agy99           ----------------------LGGDGGHAGAGGAGGEGLSGGFNTGAAG
Rv3508|M.tuberculosis_H37Rv         GAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTG
Mb3541|M.bovis_AF2122/97            GTGGAAG-TGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQ-DG
MSMEG_0868|M.smegmatis_MC2_155      SATGADS---------------LGGRGGTSWVQAGYGPTTGGKASGTAKA
TH_3810|M.thermoresistible__bu      ----------------------NGGHGGRGG-----------------FL
MAB_4284c|M.abscessus_ATCC_199      ----------------------AGLAGNAGLAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104                ---------------------AAPPPAAPPLPEAPPIPAAPPVVPVPVVV
MLBr_01556|M.leprae_Br4923          -------------------VVTVMGHVDHGKTRLLDTIRKANVREAEAGG
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GKGGNG---------------GNGGRGGLFGK------GGNAGNGADGGT
Mvan_1264|M.vanbaalenii_PYR-1       GKGGNG---------------GNGGRGSLFGR------GGNAGNGGNGGT
MMAR_4316|M.marinum_M               GAGGAGGASAVALVGGAGGAGGAGGQGGTAGD----GPGGVGGHGGSGGS
MUL_4367|M.ulcerans_Agy99           GIGGAG---------------GAGGTGGDSG-----GVGGVNGDGGAGGG
Rv3508|M.tuberculosis_H37Rv         GKGGAG---------------GAGGQGGSSGAGGTNGSGGAGGTGGQGGA
Mb3541|M.bovis_AF2122/97            GQGGTG---------------GTGGNAGAGGTGFTQGADGNAGNGGDGGV
MSMEG_0868|M.smegmatis_MC2_155      GHGGKA---------------SDGGKGGNGGDALVMAAGATGVATGNTAI
TH_3810|M.thermoresistible__bu      GIGGSG---------------GWGGHGGNGGD--------TDADGGNGGD
MAB_4284c|M.abscessus_ATCC_199      GNAGLA---------------GNAGLAGNAGLAGNAAVAGNAAVAGNAAV
MAV_4827|M.avium_104                PPVPVP----------------VPVRIPVPDPVSPPQLLAPPRLSVPQPV
MLBr_01556|M.leprae_Br4923          ITQHIG---------------AYQVGVDLDGSERLITFIDTPGHEAFTAM
                                                                  .                   

Mflv_5091|M.gilvum_PYR-GCK          GGAGGAGG-------------TGGTGGAGGTGGTGGTGGIG---------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGG-------------TGGTGGNGGTGGTGGTGGIG---------
MMAR_4316|M.marinum_M               GGIGGTGGDGYQ---------SGDVGGQGGEGGAGGAAGAGGEAGAQGLA
MUL_4367|M.ulcerans_Agy99           GGRGGDGGSSTS---------TSGVGGAGGAGGNGGNAGFG--------V
Rv3508|M.tuberculosis_H37Rv         GGAGGAGADNPTGIGG--AGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSV
Mb3541|M.bovis_AF2122/97            GGNGGNGADNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG-TGGQQGNG
MSMEG_0868|M.smegmatis_MC2_155      GGNGGAASAN------------GAVGGNGGFTNIAAIHGSITDSSATSGH
TH_3810|M.thermoresistible__bu      GGNG-------------------GSAGRGGTGGLRGVFGIN---------
MAB_4284c|M.abscessus_ATCC_199      AGNAAVGG----------------VLNTGVSGAIGGSSHVG---------
MAV_4827|M.avium_104                QPPVRVPQPPSP----------PQVGGTVPQSPPQHQTPPG---------
MLBr_01556|M.leprae_Br4923          RARGAKATDIAIL---------VVAADDGVMPQTVEAINHAQAADVPIVV
                                                              .                       

Mflv_5091|M.gilvum_PYR-GCK          GAGSTGGTGGTGGTG-----------------------GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GAGSTGGTGGTGGTG-----------------------GTGGTGGTGGTG
MMAR_4316|M.marinum_M               GAGGTGGTGGQGGTGGIGAQGSNGHGVGGRPGTAGAVGGAGGAGGQGGAA
MUL_4367|M.ulcerans_Agy99           SAGGTGGSAGDGGAG----------------------GGAGGVDGVGGAS
Rv3508|M.tuberculosis_H37Rv         GNAGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNS
Mb3541|M.bovis_AF2122/97            GNGGNGGTGGKGGTGGAG-MNSLDPLLAAQDGGQGGTGGTGGNAGAGGTG
MSMEG_0868|M.smegmatis_MC2_155      GGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKG----KAAGGNGGDGGFN
TH_3810|M.thermoresistible__bu      GGNGRAGLGGRGXXX------------------------XGGGVGAAVRS
MAB_4284c|M.abscessus_ATCC_199      -GAINESLGGSGSVG-----------------------GSTAVGGGAHTG
MAV_4827|M.avium_104                -EGTPPKPDGPGNYGGG-------------------HVPTPGAGGSGGSG
MLBr_01556|M.leprae_Br4923          AVNKIDKEGADPAKIR----------------------GQLTEYGLVAED
                                             .                                  *     

Mflv_5091|M.gilvum_PYR-GCK          ------------GTGGTGGTGGKGGTG-----GTGGAGGTGGDGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ------------GTGGTGGTGGKGGTG-----GTGGDGGTGGTGGTGGTG
MMAR_4316|M.marinum_M               GLDGTAGDGGVGGTGGRGGAGGDGAGG----VGHQLAGGAGGDGGAGGAA
MUL_4367|M.ulcerans_Agy99           ------------GNGGAAGAGGAGGSG----IGAGIDGGAGGAGGTGGAA
Rv3508|M.tuberculosis_H37Rv         GVGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAG
Mb3541|M.bovis_AF2122/97            FTQGADGNAGNGGDGGVGGNGGNGADN-TTTAAAGTTGGAGGAGGAGGTG
MSMEG_0868|M.smegmatis_MC2_155      -----------GTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRG
TH_3810|M.thermoresistible__bu      ------------GNGVFSGGGGTPSAG------FGVPTTIQFPAGSCTSR
MAB_4284c|M.abscessus_ATCC_199      -----------VGGGVSTGVGVGSHVG------GGISESLGGSGSVGGST
MAV_4827|M.avium_104                -----------GGHVPTPGAGGSGGSG-------GGHVPTPGTGGPGGTG
MLBr_01556|M.leprae_Br4923          FG----------GDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSG
                                                      . .                             

Mflv_5091|M.gilvum_PYR-GCK          GTG---------------GTGGTGGTGGTGGAGDG---------------
Mvan_1264|M.vanbaalenii_PYR-1       GTG---------------GTGGTGGTGGTGGAGDG---------------
MMAR_4316|M.marinum_M               GVGGAAGA-GSGGVVGAAGTGGTGGAGGNGGAGDTGVAASTPGDPGGVGF
MUL_4367|M.ulcerans_Agy99           GFP------GGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGW
Rv3508|M.tuberculosis_H37Rv         GAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSG---F
Mb3541|M.bovis_AF2122/97            GTGGAAGT-GTGGQQGNGGNGGNGGTGGKGGTGGDGALAGSSGGAGGKGG
MSMEG_0868|M.smegmatis_MC2_155      GDG---------------GTFVNAGANGNGGAGGAGGVSEGEGGTGGHGG
TH_3810|M.thermoresistible__bu      AVS-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AVG-----------------------------------------------
MAV_4827|M.avium_104                GSG-----------------------------------------------
MLBr_01556|M.leprae_Br4923          MEAQG---------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTGGTGGQGGQGGQG-GTGGTGGQGGLGGGGGT------------
Mvan_1264|M.vanbaalenii_PYR-1       LGGTGGTGGTGGFGGQGGQG-GTGGTGGQGGLGGVGGT------------
MMAR_4316|M.marinum_M               AGGAGGAGGAGGASGVGGVN-GVGGAGGDGGTGGAGGAGAGGDRTDGGRG
MUL_4367|M.ulcerans_Agy99           AGGAGGAGGAGGSAAFNGVN-GAGGAGGNGGAGGGGGAGASG--------
Rv3508|M.tuberculosis_H37Rv         DGGQGGQGGAGGSAGAGGIN-GAGGAGGNGGDGGDGATGAAGLGDNGGVG
Mb3541|M.bovis_AF2122/97            NGGDAGKAGTGSAPGTAGTG-GDGGKGGNGGIGAAGTTGPVGTGASGGTG
MSMEG_0868|M.smegmatis_MC2_155      DGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDP--------
TH_3810|M.thermoresistible__bu      --REGIMPSSRAASARAGAACASSTSRSRRSFCCSRA-------------
MAB_4284c|M.abscessus_ATCC_199      GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG--------
MAV_4827|M.avium_104                -GGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAG------
MLBr_01556|M.leprae_Br4923          VAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG---
                                                               .                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               GVGGAGGDAGAGGVTGAGGSGGGVGNAGVGGAGGVGGAGGAGGAADGPGL
MUL_4367|M.ulcerans_Agy99           --------------IGAG--------------------------------
Rv3508|M.tuberculosis_H37Rv         GDGGAGGAAGNGGNAGVG-LTAKAGDGGAAGNGGNGGAGGAGGAGDN---
Mb3541|M.bovis_AF2122/97            GSGGAGGTGGDGGAANGG-------TAGAGGAGGNGGKGGDGGAGVTSST
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----GGQGGTGGTGGQGGTG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----GGTGGTGGTGGQGGTG------------------------------
MMAR_4316|M.marinum_M               FGYDGGAGGAGGIGGAAGVGGSNGAGGTGGAGGVGGVGADSGLASRPGGA
MUL_4367|M.ulcerans_Agy99           --VAGGDGGTGGTGGAAGTG----------------------------GA
Rv3508|M.tuberculosis_H37Rv         -NFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGT
Mb3541|M.bovis_AF2122/97            AGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGGDGGD-------GAA
MSMEG_0868|M.smegmatis_MC2_155      --SHTGAGGNGGNGGAGRIRVNNG----------------------TATG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----GGAHTGVGGGVNTGVG------------------------------
MAV_4827|M.avium_104                --TPGGGLGGFGGGHAPAPG------------------------------
MLBr_01556|M.leprae_Br4923          ----VDIEAALPSSPVQVIG------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -GTGGTGGTG----------------GTGGAGGDG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -GTGGTGGTG----------------GTGGAGGDG---------------
MMAR_4316|M.marinum_M               GGAGGTGGAGGGAGSGAGGLGAGGDGGTGGAGGAGGVGSSAGWGSGLAGQ
MUL_4367|M.ulcerans_Agy99           AGTGGTGGAAGAAGS-------AGDGGAGGAGGAG---------------
Rv3508|M.tuberculosis_H37Rv         LGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGGDGGDGASGL
Mb3541|M.bovis_AF2122/97            GAVGISGATGAGDGGHGGTGGAGGNGGTGGAGGSGIDGVGG--GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      TATGGNGGNGGNGD---------ADGHRGGKGGDG---------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               VGGAGGVGGAGGDSGGLGGTNGDGGAGGLGGRGGAGGSSTTVAGAGGGGG
MUL_4367|M.ulcerans_Agy99           ------------DDGSAG--------------------------------
Rv3508|M.tuberculosis_H37Rv         GLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGD------GGDGAT
Mb3541|M.bovis_AF2122/97            NGGNGAIGGAGGDAGGSGNSGGNGGTGGKGGNAGAGG-------AAGSNG
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               RGGDGGSAGGGVGGGGVGGAAGSGGAGGAGGRGIDSYAAAGGRGGDGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAG
Mb3541|M.bovis_AF2122/97            GTVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGTGGRGGSGGAG
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------------------GL
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------------------GL
MMAR_4316|M.marinum_M               GIGGGGGLSGIGGAGGQGGSGGAAGTGG-DVGGSPGEVGGAGGGGGFGGA
MUL_4367|M.ulcerans_Agy99           -----------------------------VVSGDPGTAGKAG------GA
Rv3508|M.tuberculosis_H37Rv         GAGGAGDNNFNGGQGGAGGQGGQGGLGG-ASTTSINANGGAGGNGGTGGK
Mb3541|M.bovis_AF2122/97            GDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGGQGGQGGSGGA
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------GEALIRATVIGSNASGTAT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGLGGFGG-----------------------SGGTGGQGGLGGPGGS---
Mvan_1264|M.vanbaalenii_PYR-1       GGLGGFGG-----------------------VGGTGGQGGQGGPGGS---
MMAR_4316|M.marinum_M               GGAGGVGGGAGGSGGVGGSGGNGGLGVATGGAGGVGGQGGAAGAGGAAGA
MUL_4367|M.ulcerans_Agy99           GGAGGVGG--------------------NGVAGGVNGSGGAGGAGGAGGT
Rv3508|M.tuberculosis_H37Rv         GGAGGAGTLG------------------VGGSGGTGGDGGDAGSGGGGGF
Mb3541|M.bovis_AF2122/97            GGAAGAGGAG-------------------GGANGTAGNGGQGGAGGTGGA
MSMEG_0868|M.smegmatis_MC2_155      GGDGGNGG----------------------TLGATNGTGGAATIVAYNVV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------GGLGGGGGHAPAPG----
MLBr_01556|M.leprae_Br4923          -------------------------------FTSVPGAGDNFLVVDE---
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---------------------------------------TGGAGGAGGQA
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------------------TGGAGGAGGQA
MMAR_4316|M.marinum_M               GATA--AGAGGVGGLGGDGGNGGNGV-RGAAGVAGGDGAVGGGGGAGGAG
MUL_4367|M.ulcerans_Agy99           GG----AGASGVP-----------------ASVDGGD---GGAGGAGGAA
Rv3508|M.tuberculosis_H37Rv         GGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAG
Mb3541|M.bovis_AF2122/97            GAASS-ATNGGSGGAGGTGGAGGTGG----AGGDGVGGAGGGNGGHGGDA
MSMEG_0868|M.smegmatis_MC2_155      QANPQASGTATDG--------------------HGGSGINGGHGGNGGQG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------VGSHVGGGISE
MAV_4827|M.avium_104                ----------------------------------------GGLGGFGGGH
MLBr_01556|M.leprae_Br4923          ---------------------------------------DRIARQIADRR
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTAGKGGLFGGS--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GVAGKGGLFGGS--------------------------------------
MMAR_4316|M.marinum_M               GQGGAGVTGGSAGAGGQGGNGGLGGPGGDGGSAVRYQRVGGAGGVGGVGG
MUL_4367|M.ulcerans_Agy99           GTGGSGGSAGNTGAGG----------------------------------
Rv3508|M.tuberculosis_H37Rv         GINGAGGAGGTGGAGGDGAPATLIG--GPDGGDGGQGGIGGDGGNAGFGA
Mb3541|M.bovis_AF2122/97            GDGGNGANGNNRSSGSFLAAGGTGGAAGDGGQGGQGGAGGGAGGQGGAGG
MSMEG_0868|M.smegmatis_MC2_155      TIEANGPSAVASGIG-----------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SLGGSGSVGGSTAVG-----------------------------------
MAV_4827|M.avium_104                SGGGLGGLGGGHK-------------------------------------
MLBr_01556|M.leprae_Br4923          SARKRNALAARSRKR-----------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               AAGAGGAAGQGGGGAVGAAGVGGTGGVGGNGGAGDAGVAGADGGGAGGSG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAG-ADGDPSIDGGQG
Mb3541|M.bovis_AF2122/97            AGGTGGNGGNITGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGAG
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------------GSAGKAGATGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------GSAGTAGVTGASG-------------
MMAR_4316|M.marinum_M               WAGGAGGAGGQGGAANGGVA----GDGGVGGNGGVGG--------VGGRG
MUL_4367|M.ulcerans_Agy99           -AGGAGGAGG--SAASTGVN----GDGGAGGAGGVGG--------LGG--
Rv3508|M.tuberculosis_H37Rv         GAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSG
Mb3541|M.bovis_AF2122/97            GDGGAGGTGGDRTVGGGTVPAGSGGQGGNAGGGGAGGQG-------GADG
MSMEG_0868|M.smegmatis_MC2_155      -AGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATG-------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------GGAHTSAINDALG-------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          -----------ISLEDLDSALKETSQLNLILKGDNAG-------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4316|M.marinum_M               GDGANG--APGGGIDGTGRPGGAGGQGGSGGRAGFGGAAGAGEGGEYGAA
MUL_4367|M.ulcerans_Agy99           -DSAAT--AGGG--------------------------------------
Rv3508|M.tuberculosis_H37Rv         GTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNG
Mb3541|M.bovis_AF2122/97            GSGGDGGDAGTGGNGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------------T
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ASGGKGAQG-----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ASGGKGAQG-----------------------------------------
MMAR_4316|M.marinum_M               GVGGNGGDGGAGGRGGYGTTGSGGLFGGSGGHGGVGGIGGNGGSAAAGGV
MUL_4367|M.ulcerans_Agy99           GAGGDGGKGGAGG----------------------------------AGV
Rv3508|M.tuberculosis_H37Rv         FAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGG-DGQNGTTGVASEGGA
Mb3541|M.bovis_AF2122/97            GTGGNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTGSGN
MSMEG_0868|M.smegmatis_MC2_155      ATGGDGGKAT----------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------ATGAQGATGAQGATG-------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------ATGAQGATGAQGATG-------
MMAR_4316|M.marinum_M               NGNGGNGGIGGNAGDAGNGANGSLLHHAGDGGNGGRGGAGGAGGFAGDGE
MUL_4367|M.ulcerans_Agy99           NGVGG-----------------------GDGGKGGTGGAGGAG-------
Rv3508|M.tuberculosis_H37Rv         GGQGGDGGQGGIGGAGGNAGFGAG--VPGDGGIGGTGGAGGAGGAGADGD
Mb3541|M.bovis_AF2122/97            GGNGGSGGNGGNAGMGGNSGTGS-----GDGGAGGNGGAAGTGGTGGDGG
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------GTASQGGNGGPSWVQS------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------ATGAAGKAGATGAA
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------ATGASGAQGSAGSA
MMAR_4316|M.marinum_M               GSGG--TAGSGGNGGKGGNAGAGGNG-VPAAGAAAGNGGLGGSGGAGGSG
MUL_4367|M.ulcerans_Agy99           --------------------GAGSDG-IIPS-----NGGLGGNGGNGGNG
Rv3508|M.tuberculosis_H37Rv         PS------IDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAG
Mb3541|M.bovis_AF2122/97            LTGTGGTGGSGGTGGDGGNGGNGGNGADNTANMTAQAGGDGGNGGDGGFG
MSMEG_0868|M.smegmatis_MC2_155      -------------------GYGSTLGGNATGTATAGKGGEASNGGVAGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          -------------------------------------TVEALEEALMGIQ
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GAAG---------AAGSAGTTGAQGSAG---------------TNGANGA
Mvan_1264|M.vanbaalenii_PYR-1       GSAG---------VAGSAGTTGAQGSAG---------------TNGANGA
MMAR_4316|M.marinum_M               AIGAAAGG-----AGGAGGNGGTGGNAGIGVMRGAS--TPALAGDGGVGG
MUL_4367|M.ulcerans_Agy99           GQ-AFGDG-----VGGAGGIGGKGGNAAIGTIVIN-------GGVGGAGG
Rv3508|M.tuberculosis_H37Rv         GNGGDGDGF----IGGSGGTGGTGGDAGVGGLANTG-GTAGNAGIGGAGG
Mb3541|M.bovis_AF2122/97            GGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGHGPLTDDPGGNGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GNALVMAAG---TTGVATGNTATGGDGGAATTAGAT------GGAGGFSN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------GSGSVGG
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VDDEVALRVIDRGVGGITETNVNLASASDAIIIGFN------VRAEGKAT
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          NGSQGAAGKAGATGTTGATGAAGEDGDAG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       NGSQGAAGKAGATGTTGATGAAGDAGDPG---------------------
MMAR_4316|M.marinum_M               AGGLGGVARS-VGGVGG-VGGDGGSGGTGGIGTTGNSA-TNGYGGAGGAG
MUL_4367|M.ulcerans_Agy99           SGGLGGATEDGVGGVGC-AGGAGGNGGRGDMLFT--------------VG
Rv3508|M.tuberculosis_H37Rv         RGGDGGAGDSGALSQDG-NGFAGGQGGQGGVGGNAGAGGINGAGGTGGTG
Mb3541|M.bovis_AF2122/97            NGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTGGEG--GEVGGAGGTG
MSMEG_0868|M.smegmatis_MC2_155      IAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYD------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STAVGGGAHTSAINESMNSSINASHSSSMNESFG----------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEEN------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -SGGSGING--------GAGGAGGAGGEGGEG-------------GDGGK
Mvan_1264|M.vanbaalenii_PYR-1       -SEAVDING--------GAGGAGGAGGEGGEG-------------GAGGA
MMAR_4316|M.marinum_M               GAGGVGGNGGFAALGTGGAAGSGGGGGTGGAGGVSDSPTTSRSVGGAGGV
MUL_4367|M.ulcerans_Agy99           GSGGTGGDG--------GGGGSASGSGTGGSG-------------GTGGV
Rv3508|M.tuberculosis_H37Rv         GAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGI
Mb3541|M.bovis_AF2122/97            GAAGNGGDGGTGGTG-GGDGGAGGTGGTGGTGGLGDP-----RVGGSGGD
MSMEG_0868|M.smegmatis_MC2_155      -PAGPVGSKIANSSAVAGNGGDGGVNGTGGASG------------GDGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------SSMGSHGAAGTGFEAQG-----------HAQGH
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          QLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGAGAEGGAGGGGGAG------GSG-------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGDGSEGGAGGSGGAG------GSG-------------------------
MMAR_4316|M.marinum_M               GGVGGNGGIGGNGQIG------GDGGSGGAAGAGGAGAQNLTRSIQSAN-
MUL_4367|M.ulcerans_Agy99           GGIGGDGKLGGFGGDG------GDGGDGG---------------------
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASG
Mb3541|M.bovis_AF2122/97            GGTGGSGGAAGNGGNG------GNAGAGGNG-------------------
MSMEG_0868|M.smegmatis_MC2_155      GGNTSVWKSGGQTADG------EHN-------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ASETAHTTLPGAEHH-----------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          TSLRREKDDVTEVREG----------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------AGGAGGAGGSGGSGGSGGS-------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------TGGAGGAGGSGGSGGSGGA-------------------------
MMAR_4316|M.marinum_M               ------FGGAGGAGGVGGFGGVGGT----------------GASGLGGSG
MUL_4367|M.ulcerans_Agy99           ------FGVIGGQGGGGGFGGLGGT----------------GAG------
Rv3508|M.tuberculosis_H37Rv         DGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTP
Mb3541|M.bovis_AF2122/97            ------NGGTGGAGGIGGTGGNGGD---------------AEPGVPPGAG
MSMEG_0868|M.smegmatis_MC2_155      ------TGGNGGNGGDGSEPGPGGN-------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          -------FECGMTLGYSDIKEGD---------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------GGSGGAAGDSDD------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------GGSGGAAGDSD-------
MMAR_4316|M.marinum_M               GIGGDGGAGGVGGDCSVPLSPGNGGDGGAGGDGGDGGDGGNGQPGGPGGA
MUL_4367|M.ulcerans_Agy99           --------------------------------GAPSDKGINGEPGNPG--
Rv3508|M.tuberculosis_H37Rv         TGSGTEGTGGDGGDAGAGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGF
Mb3541|M.bovis_AF2122/97            GAGGAGTTGGKGGTGGNGSGTGSGGTGGDGGTGGGGGNGGTGWNGGKGDT
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------GAGGAGGNGGTGGTTAGGSG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------VIESYELVEKQRA-----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------
MMAR_4316|M.marinum_M               GGGAASGGAGGYGQLGNGAAGADGNNGTPGADG--
MUL_4367|M.ulcerans_Agy99           -----------------------------------
Rv3508|M.tuberculosis_H37Rv         GGGAGAGGLGGSGAGG-GTDGDDGNGGSPGTDGS-
Mb3541|M.bovis_AF2122/97            GSGGGAGDGGKAPAGGTGGAGGDGGAGGKGGSGGV
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGNGGNGGADGTPGTAGTTGANNP-------
TH_3810|M.thermoresistible__bu      -----------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------
MAV_4827|M.avium_104                -----------------------------------
MLBr_01556|M.leprae_Br4923          -----------------------------------