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MSYLIVAPEAMTAAAGDLAGIGSSVAAANAAAAGPTTAMLTAAADEVSTAIAAFFSAHAADYQRLAGQAA ALHTQLERVLSAGAVAYAAAETTGTSPLQLAINAVSAPAQSLLARPIIGNGANATTPGGNGGDGGWLFGS GGNGAAGAAGQAGGSGGSAGLLGNGGAGGAGGTGGARGGNGGSGGLLFGGGGIGGTGGTGAAGAGMGGMG GNGGSGSWLIGGGGAGGAGGIGGTGGGTGGVGGTGGDAGWLVGAGGSGGSGGIGATGTGSGGAAGNGGNG GAGGLFMNGGDGGAGGQGGDGAAGAAAAAAGGTGGDGGLGGNGGAGGAGGGGPVLFGHGGAGGLGGQGGT GGIGGTGGAGTTSIAAGTGGNGGAGGAAGGGGTAGAAGPLTNAGLAGGFGTGGTGGTGGTGGAGAPGIDG AALGEGGTNGYIGGNGGNGGAGGAALGGGAAGDGGQGGHGGAGGMGGAGANGITGGGVTGAGGNGGDGGQ GGEPGTGGAAGSGGGGQTGSLGIGGTGGHGGAGGDGTPGGNGAAGPTAGTGDPGVDGGAGGNGGAGGQGG SNGTGGDGGTGGSGATGGDGGTGGAGTATDAGGTGGQGGVGGAGGAPGAAGLAGTGGQAGNEGVGGNGGQ GGHGGAGGNGVDGADANVFTGDNGGDGTAGGKGGDGGAGGAAGANGGTGGGGGIGGGGGVGGDGGNGGSG NTGTSSAPAGGTGGIGGTGADGGAGGNGGAAGGAGGTGGQGGTGGGAGKGGTGGAGGAAVTPGLGIGDEP AGGTGGTGGHGGTGGHGGTGGAAGNGGAGGAGGQAGDGGSGGEGGDGGTGAQGTTVSLPGSGGNAGNGGN AGGGGVGGTGGAGATGAPAGRGGTGGNGGNAGAGGKGGAGAFGGAGSSPGFLSPAGNGGAGGDAGTAAAG GDGGAGGAGPSGGNGGTGGNGGHGGNGGNGAEGAIGAQFVPASSLPTPSGGAGGDGGNGSNGGAPGAGGS AGAGTGGSTGGQGTGGDGGNGGNGGNGADGANAVNIAFTPNEPQATAGNPGGSGITGEIGGSGTNGSPAT LPTTQVQQGGDGGAGGTGTNAANNEVATGGEGGTGGTGSAGGPGGDGGVGGDASETGTDGVAVGGQGGQG GAGGQFGGGGNGGDGGNVTAGSAGSTAGNGGNGGNANNGTIEGSPAGGNGSAGGDGGDGGDVASGATGTA GTGGTGGAGNDGTINAGTGGNGGAGGRAGSGGANGGNGGTGGTGGDGGKGGGGAVGGSGGDGGDGGINNG AGANGNGGGGGTGGTGSIGAAGGNGGQGGSGGAAGSGGGTAGNGGAGGVGGAGGTGGVGGGGGDGGAGAL AGTGGTGGSGGTGGASGAGGSGGGGGLSGSGQSGANGGTGGASQEGQDGQASTDSDGGAGGAGGTGGSGG AAGAGGQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4995 | - | - | 100% (1408) | PE-PGRS family protein |
| M. marinum M | MMAR_1594 | - | 0.0 | 48.32% (1668) | PE-PGRS family protein |
| M. marinum M | MMAR_4999 | - | 0.0 | 49.09% (1599) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3537 | PE_PGRS53 | 0.0 | 60.95% (1429) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 48.20% (805) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3507 | PE_PGRS53 | 0.0 | 56.48% (1427) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 6e-14 | 42.71% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-52 | 31.81% (525) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 9e-26 | 44.44% (171) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-175 | 40.66% (1129) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-44 | 40.40% (302) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 49.01% (1112) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 47.97% (836) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3537|M.bovis_AF2122/97 MSFVLVSPETVAAVATDLKRIGASLAHENASAAASTTAVVSAAADEVSTA
Rv3507|M.tuberculosis_H37Rv MSFVLVSPETVAAVATDLKRIGASLAHENASAAASTTAVVSAAADEVSTA
MMAR_4995|M.marinum_M MSYLIVAPEAMTAAAGDLAGIGSSVAAANAAAAGPTTAMLTAAADEVSTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 -----MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAA
MUL_4367|M.ulcerans_Agy99 MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 VAALFSQHAQGYQAAAAQVAAFHSRFVQALTAGAGAYAFAEAANASPLQS
Rv3507|M.tuberculosis_H37Rv VAALFSQHAQGYQAAAAQVAAFHSRFVQALTAGAGAYAFAEAANASPLQS
MMAR_4995|M.marinum_M IAAFFSAHAADYQRLAGQAAALHTQLERVLSAGAVAYAAAETTGTSPLQL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------MMFLAPPGGPGPISAAIQLTSTGSEA
MSMEG_0868|M.smegmatis_MC2_155 LAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNT
MUL_4367|M.ulcerans_Agy99 IAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 AMG----AVSASAQTLLSRPLIGNGANATTPGGNGGDGGWLFGSGGNGAP
Rv3507|M.tuberculosis_H37Rv AMG----AVSASAQTLLSRPLIGNGANATTPGGNGGDGGWLFGSGGNGAP
MMAR_4995|M.marinum_M AIN----AVSAPAQSLLARPIIGNGANATTPGGNGGDGGWLFGSGGNGAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------MVTFGGG
Mvan_1264|M.vanbaalenii_PYR-1 TEP--------------------------------------WYVVSFGGS
MSMEG_0868|M.smegmatis_MC2_155 TDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTT
MUL_4367|M.ulcerans_Agy99 LEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 GAAGQ--------------------------------SGGNGGSAGLWGN
Rv3507|M.tuberculosis_H37Rv GAAGQ--------------------------------SGGNGGSAGLWGN
MMAR_4995|M.marinum_M GAAGQ--------------------------------AGGSGGSAGLLGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ATPTP----------------------------------------TSLGA
Mvan_1264|M.vanbaalenii_PYR-1 GAPTP----------------------------------------NNLAA
MSMEG_0868|M.smegmatis_MC2_155 LIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVAS
MUL_4367|M.ulcerans_Agy99 LGAAG-------------------------------ANGGAGGSAGLIGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 GGAGGAGGSGG--------------AAGGNGGNGGWLFGAGGTGGIGGTG
Rv3507|M.tuberculosis_H37Rv GGAGGAGGSGG--------------AAGGNGGNGGWLFGAGGTGGIGGTG
MMAR_4995|M.marinum_M GGAGGAGGTGG--------------ARGGNGGSGGLLFGGGGIGGTGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAVDLS------------------------GTSCG----------LICNG
Mvan_1264|M.vanbaalenii_PYR-1 SLVDLS------------------------GTSCG----------LICNG
MSMEG_0868|M.smegmatis_MC2_155 AVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNG
MUL_4367|M.ulcerans_Agy99 GGVGGAG------------------GVGAAGMTGGSGGAGGGGGWLWGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------MS
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 APGA-MGGTGGNGGNGALLIGGGGLGGAGGMGGTGGGTGG--TGGNGGNG
Rv3507|M.tuberculosis_H37Rv APGA-MGGTGGNGGNGALLIGGGGLGGAGGMGGTGGGTGG--TGGNGGNG
MMAR_4995|M.marinum_M AAGAGMGGMGGNGGSGSWLIGGGGAGGAGGIGGTGGGTGG--VGGTGGDA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QDG---TGQN-----GGILFGNGGSGWNSDVVGMDGGNGG----------
Mvan_1264|M.vanbaalenii_PYR-1 QDG---TGQN-----GGILFGNGGSGWNSEIAGVSGGNGG----------
MSMEG_0868|M.smegmatis_MC2_155 ING---TADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGG----------
MUL_4367|M.ulcerans_Agy99 GSGG-AAGAGGSGGSGGWLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVG----------
MAV_4827|M.avium_104 ---------------MNIVLGVSMAPSSIQMVVLEGEYAD----------
Mb3537|M.bovis_AF2122/97 ALLIGAGGVGGAGGIGGQGTGAGGAAGAGGTGGNGGAGGLFMNGGDGGAG
Rv3507|M.tuberculosis_H37Rv ALLIGAGGVGGAGGIGGQGTGAGGAAGAGGTGGNGGAGGLFMNGGDGGAG
MMAR_4995|M.marinum_M GWLVGAGGSGGSGGIGATGTGSGGAAGNG---GNGGAGGLFMNGGDGGAG
TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGDGGDG
Mflv_5091|M.gilvum_PYR-GCK ----NGGLFGGNGGNG----GNGLGGGNGGNGGNAGAFALFGNGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1 ----NAGLFGGNGGNG----GNGLGSGDGGNGGDAGLFSLFGRGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 ----NAGLFG-NGGNG----GVGWAGLDGGNGGSGG--LLMGIGGAGGAG
MUL_4367|M.ulcerans_Agy99 VAPGEAGAVGFAGGAG----GAGGAGGNGVGGGVNGAGGAGGAGGVGGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPS
MAV_4827|M.avium_104 ------------GATVEEDAIDVTGADDAATASAPDRVISAILGTREGAA
Mb3537|M.bovis_AF2122/97 GQGGDGAAGDAAASAGGTGGK-GGQGGDGGTGGAGGAGPVLFGHGGAGGM
Rv3507|M.tuberculosis_H37Rv GQGGDGAAGDAAASAGGTGGK-GGQGGDGGTGGAGGAGPVLFGHGGAGGM
MMAR_4995|M.marinum_M GQGGDGAAGAAAAAAGGTGGD-GGLGGNGGAGGAGGGGPVLFGHGGAGGL
TH_3810|M.thermoresistible__bu GLG-------------GNGGHGGGTGIIS--------------------L
Mflv_5091|M.gilvum_PYR-GCK GVGVVGATGAVG--APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGA
Mvan_1264|M.vanbaalenii_PYR-1 GVGIAGATGAVG--APGVAGATGATGVTSNVTGGNGADAVGYGATGAAGA
MSMEG_0868|M.smegmatis_MC2_155 GVGADGTSAHVDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGA
MUL_4367|M.ulcerans_Agy99 GAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGTGGTGGAAGVAGTGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLL
MAV_4827|M.avium_104 DAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNV
Mb3537|M.bovis_AF2122/97 GGQGGTGGMGGAGG-----------DGTTVIAAGTGGEGGTG--------
Rv3507|M.tuberculosis_H37Rv GGQGGTGGMGGAGG-----------DGTTVIAAGTGGEGGTGGAAGAGGA
MMAR_4995|M.marinum_M GGQGGTGGIGGTGG-----------AGTTSIAAGTGGNGGAGGAAGGGGT
TH_3810|M.thermoresistible__bu LSLAGNGGNGG---------------NGYRTTDNNALDGGHGG-------
Mflv_5091|M.gilvum_PYR-GCK AGAAGAAGAAG--------------AVGSAGAAGEAGETGTWG-------
Mvan_1264|M.vanbaalenii_PYR-1 AGAAGAAGKAG--------------AVGSAGTAGSAGAPGVWG-------
MSMEG_0868|M.smegmatis_MC2_155 AGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQS-----
MUL_4367|M.ulcerans_Agy99 DGGAGGAGSDAS------------LAGQAGFAGGSGGAGGVGGSA-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DLSFGDLQFGNR--------------DTTAIGDGAVAVGGSNSGP-----
MAV_4827|M.avium_104 GGAMGYERTAVLLVEP----------DTATLAVVETSDGSIPDVY-----
Mb3537|M.bovis_AF2122/97 ----------------------GTGGTGGNGADAAAVVGFGANGDPGFAG
Rv3507|M.tuberculosis_H37Rv AGARGALTSGGLAGGVGAGGTGGTGGTGGNGADAAAVVGFGANGDPGFAG
MMAR_4995|M.marinum_M AGAAGPLTNAGLAGGFGTGGTGGTGGTGGAGAPGIDGAALGEGGTNGYIG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------NAGLPGKAGDAGGAG----------------AVG
Mvan_1264|M.vanbaalenii_PYR-1 ----------------NAGLPGAAGAAGGAG----------------AIG
MSMEG_0868|M.smegmatis_MC2_155 ----------------TAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIG
MUL_4367|M.ulcerans_Agy99 ----------------GAGGVNGSGGDGGAG----------------AAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 GKGGNGGIGGAAVTGGVAGDGGTGGKGGTGGAGGAGN---DAGSTGNPGG
Rv3507|M.tuberculosis_H37Rv GKGGNGGIGGAAVTGGVAGDGGTGGKGGTGGAGGAGN---DAGSTGNPGG
MMAR_4995|M.marinum_M GNGGNGGAGGAALGGGAAGDGGQGGHGGAGGMGGAGANGITGGGVTGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAG------TVGTAGATGGTG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1 TAGVAG------AAGTAGATGGTG--------------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG-----------TA
MUL_4367|M.ulcerans_Agy99 GAGGAS--ATVAGSGGVGGDGGAGG------------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------I
MAV_4827|M.avium_104 ------------------------------------------------KQ
Mb3537|M.bovis_AF2122/97 KGGDGGIGGAGGAGGAAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVNGA
Rv3507|M.tuberculosis_H37Rv KGGDGGIGGAGGAGGAAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVNGA
MMAR_4995|M.marinum_M NGGDGGQGGEPGTGGAAGSGGGGQTGSLGIGGTGGHGGAGGDGTPGGNGA
TH_3810|M.thermoresistible__bu NGGNVGFFSLFNLGG--------------------AGGWGGSG-------
Mflv_5091|M.gilvum_PYR-GCK TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLG-------
Mvan_1264|M.vanbaalenii_PYR-1 VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAG-------
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDG-------
MUL_4367|M.ulcerans_Agy99 AGGGVGAASLGGDGGHAGAG--------------GAGGEGLSGGF-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASGQGSTAVNGDVRDSNIIN---------------ADHGSNVG-------
MAV_4827|M.avium_104 QIRAESYGDAAGQLSAMVAG--------------LEKLESLPG-------
Mb3537|M.bovis_AF2122/97 DN----TLNPDTPGGAGEPGGAGGAGGAGGAAG--GPGGTGGTGGNGGN-
Rv3507|M.tuberculosis_H37Rv DN----TLNPDTPGGAGEPGGAGGAGGAGGAAG--GPGGTGGTGGNGGNG
MMAR_4995|M.marinum_M AGPTAGTGDPGVDGGAGGNGGAGGQGGSNGTGGDGGTGGSGATGGDGGTG
TH_3810|M.thermoresistible__bu -----------------VDG------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------ETGTTGGAGGVGGQ-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------ETGVTGGVGGIGGQ-------------------
MSMEG_0868|M.smegmatis_MC2_155 -----------------IDGGTGGAGGMGEIYS-----------------
MUL_4367|M.ulcerans_Agy99 -----------------NTGAAGGIGGAGGAG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------VDQSQTRVGG-----------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3537|M.bovis_AF2122/97 -----------------AGNNSTNAPVGGEGGAGGDGGAGGAGGAAN-GG
Rv3507|M.tuberculosis_H37Rv GNGGNGGNGGNGGNGGNAGNNSTNAPVGGEGGAGGDGGAGGAGGAAN-GG
MMAR_4995|M.marinum_M G----------------AGTATDAGGTGGQGGVGGAGGAPGAAGLAGTGG
TH_3810|M.thermoresistible__bu --------------------------VDVVGGNP----------------
Mflv_5091|M.gilvum_PYR-GCK ------------------GTAGGTGGVGGIGGAGSTGAVGGVGGKG----
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTEGGTGGVGGVGGVGATGGAGGVGGKG----
MSMEG_0868|M.smegmatis_MC2_155 ------------------GADGEATGISAGGDGGSATGADSLGGRGGTSW
MUL_4367|M.ulcerans_Agy99 ------------------GTGGDSGGVGGVNGDGGAGGGGGRGGDGGSST
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------DYTNVSGHGSADIDKSVTVVDDHSQRNT
MAV_4827|M.avium_104 -------------------------GLLLVGSGVDVAPLKQVLQTTTFLD
Mb3537|M.bovis_AF2122/97 TAGSQG--------------TGGVGGDGGAGGNGGGGKAGTG--------
Rv3507|M.tuberculosis_H37Rv TAGSQG--------------TGGVGGDGGAGGNGGGGKAGTG--------
MMAR_4995|M.marinum_M QAGNEG--------------VGGNGGQGGHGGAGGNGVDGAD--------
TH_3810|M.thermoresistible__bu --------------------------DGGTPG------------------
Mflv_5091|M.gilvum_PYR-GCK IQGGQG-------------LQGGKGGDGGAGGKGGDADSMGS--------
Mvan_1264|M.vanbaalenii_PYR-1 IQGGQG-------------LQGGQGGDGGTGGTGGDATSMGE--------
MSMEG_0868|M.smegmatis_MC2_155 VQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATG
MUL_4367|M.ulcerans_Agy99 STSGVG-------------GAGGAGGNGGNAGFGVSAGGTGG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TNINDS-------------FNTDRSTNIGSGNTTNTEIGSHN--------
MAV_4827|M.avium_104 VSVAEE---------------PETALARGAALAAANAPLFAS--------
Mb3537|M.bovis_AF2122/97 NSGNFGVDGEAGFSGGAGGNGGVGGAAGANGG--------TGGSGGNGGD
Rv3507|M.tuberculosis_H37Rv NSGNFGVDGEAGFSGGAGGNGGVGGAAGANGG--------TGGSGGNGGD
MMAR_4995|M.marinum_M ANVFTGDNGGDGTAGGKGGDGGAGGAAGANGG--------TGGGGGIGGG
TH_3810|M.thermoresistible__bu ------------AHGESHTPGVYTDRQ-----------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AGATGGKGGNGGNGGRGGLFG---------------KGGN
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGATGGKGGNGGNGGRGSLFG---------------RGGN
MSMEG_0868|M.smegmatis_MC2_155 NTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGN
MUL_4367|M.ulcerans_Agy99 ---------SAGDGGAGGGAGGVDGVGGASG---------------NGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------QANIGTSTSAGGSAAVGGNAG-------------------
MAV_4827|M.avium_104 ----------STAALAYAQDPGTGAVDQYSLP------------------
Mb3537|M.bovis_AF2122/97 GGAGGIGGAGGNGIPGTGTEPAGGTGAKGGDGGDGGAGGAGGNAGGAGGN
Rv3507|M.tuberculosis_H37Rv GGAGGIGGAGGNGIPGTGTEPAGGTGAKGGDGGDGGAGGAGGNAG-----
MMAR_4995|M.marinum_M GGVGGDGGNGGSGNTGTSSAPAGGTGGIGGTGADGGAGGNGGAAGGAGGT
TH_3810|M.thermoresistible__bu --------------------------------GEDGEDGTGTGIGGRGGN
Mflv_5091|M.gilvum_PYR-GCK AGNGAD----------------------GGTGGAGGAGGTGG-TGGAGGT
Mvan_1264|M.vanbaalenii_PYR-1 AGNGGN----------------------GGTGGNGGNGGTGG-TGGNGGT
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGD
MUL_4367|M.ulcerans_Agy99 AGAGGAG---------------GSGIGAGIDGGAGGAGGTGGAAGFPGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------LAGNAGLAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 ---------------------------------DYLYVPVDPEPG-----
Mb3537|M.bovis_AF2122/97 GGAGGQGGNAGQGGAGGAGGNAVIPGDGVGKAPHGGAGGSGGDGGKGGQG
Rv3507|M.tuberculosis_H37Rv -GAGGQGGNAGQGGAGGAGGNAVIPGDGVGKAPHGDAGGSGGDGGKGGQG
MMAR_4995|M.marinum_M GGQGGTGGGAGKGGTGGAGGAAVTPGLGIGDEPAGGTGGTGGHGGTGGHG
TH_3810|M.thermoresistible__bu GG---------------------------------SSSGTHPMAEDG---
Mflv_5091|M.gilvum_PYR-GCK GG----------------------------------TGGTGGIGGAGSTG
Mvan_1264|M.vanbaalenii_PYR-1 GG----------------------------------TGGTGGIGGAGSTG
MSMEG_0868|M.smegmatis_MC2_155 GAGASVWKANGQHSTG-----------------QTDTGGNGGRGGDGGTF
MUL_4367|M.ulcerans_Agy99 GTTG-----------------------------AWGTGGAGGAGGAGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G-----------------------------------LAGNAGLAGNAGLA
MAV_4827|M.avium_104 -------------------------------------DDELAYSAVGEED
Mb3537|M.bovis_AF2122/97 GSGGTGGSGAPIGGGAGGTGGSGGHAGKGGAGGIGAQGTTITVPGNGGNA
Rv3507|M.tuberculosis_H37Rv GSGGTGGSGAPIGGGAGGTGGSGGHAGKGGAGGIGAQGTTITVPGNGGNA
MMAR_4995|M.marinum_M GTGGAAGNGG--AGGAGGQAGDGGSGGEGGDGGTGAQGTTVSLPGSGGNA
TH_3810|M.thermoresistible__bu -----EHVKA--LDGRPGLD--------GGNGSHG---------GNGGHG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG--TGGTGGTG------GTGGTGGTG---------GTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGG--TGGTGGTG------GTGGTGGTG---------GTGGKG
MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGG--AGGAGGVSE-----GEGGTGGHG---------GDGGRG
MUL_4367|M.ulcerans_Agy99 DHGGVGVNPG--DSGTAGWAG-----GAGGAGGAGGSAAFNGVNGAGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG--LAGNAGLAG-----NAGLAGNAG-------LAGNAGLA
MAV_4827|M.avium_104 AESPTVVIEKLFLPEDSEPRR-----RPVLLVGSG--------LAVVGIS
Mb3537|M.bovis_AF2122/97 GDGGNGGGGGAGGTGGDGATGTPAG---NGGNGGNAGDGGNGGSGDFGGN
Rv3507|M.tuberculosis_H37Rv GDGGNGG---------------------------NAGAGGNGGSGDFGGN
MMAR_4995|M.marinum_M GNGGNAGGGGVGGTGGAGATGAPAGRGGTGGNGGNAGAGGKGGAGAFGGA
TH_3810|M.thermoresistible__bu GRGGFLGIGGSG---------------------------GWGGHGGNGGD
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG------------------------GDGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG------------------------GTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVG--------------------LGNGGKGGNGGNGGN
MUL_4367|M.ulcerans_Agy99 GNGGAGGGGGAGASG--------------------IGAGVAGGDGGTGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAG------------------------NAGLAGNAGLAGN
MAV_4827|M.avium_104 AVLALEIALAIG--------------------------IRTTGTVALQPT
Mb3537|M.bovis_AF2122/97 TTS----GASGSGGNGGNAGTAGSGGAGGTGGTGLSGGNGGNGG------
Rv3507|M.tuberculosis_H37Rv TTS----GASGSGGNGGNAGTAGSGGAGGTGGTGLSGGNGGNGGNGGNGG
MMAR_4995|M.marinum_M GSSPGFLSPAGNGGAGGDAGTAAAGGDGGAGGAGPSGGNGGTGGNGGHGG
TH_3810|M.thermoresistible__bu -----------TDADGGNGGDG---------------GNGGSAG------
Mflv_5091|M.gilvum_PYR-GCK G---------GTGGTGGTGGAG-----------DGTGGTGGTGG------
Mvan_1264|M.vanbaalenii_PYR-1 G---------GTGGTGGTGGAG-----------DGLGGTGGTGG------
MSMEG_0868|M.smegmatis_MC2_155 GGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGN--GDA
MUL_4367|M.ulcerans_Agy99 GGAAGTGGAAGTGGTGGAAGAAG---------SAGDGGAGGAGG---AGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------AGLAGNAGLAGNAG------------LAGNAGLAG------
MAV_4827|M.avium_104 PNQHLIVPTEQAPAPPPVQASAP---------------------------
Mb3537|M.bovis_AF2122/97 DGGNGAHGTVGAQFVPATSLPTPNGGAGGNGGTGSNGGAPGPAGAPGPTT
Rv3507|M.tuberculosis_H37Rv DGGNGAHGTVGAQFVPATSLPTPNGGAGGNGGTGSNGGAPGPAGAPGPTT
MMAR_4995|M.marinum_M NGGNGAEGAIGAQFVPASSLPTPSGGAGGDGGNGSNGGAPGAGGSAGAGT
TH_3810|M.thermoresistible__bu -----------------------------RGGTGGLRGVFGINGGNG---
Mflv_5091|M.gilvum_PYR-GCK TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG---
Mvan_1264|M.vanbaalenii_PYR-1 TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG---
MSMEG_0868|M.smegmatis_MC2_155 DGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAA
MUL_4367|M.ulcerans_Agy99 DGSAGVVSGDPG-----------------TAGKAGGAGGAGGVGGNGVAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------NAAVAGNAAVAGNAAVAG---
MAV_4827|M.avium_104 -----------------------------QPKISVPEPVAAPKPLSP---
Mb3537|M.bovis_AF2122/97 G-------------GNAGSQGIGGDGGNGGDGGKGGDGADAVNVVFMPTE
Rv3507|M.tuberculosis_H37Rv G-------------GNAGSQGIGGDGGNGGDGGKGGDGADAVNVVFMPTE
MMAR_4995|M.marinum_M G-------------GSTGGQGTGGDGGNGGNGGNGADGANAVNIAFTPNE
TH_3810|M.thermoresistible__bu ---------------------RAGLGGRGXXXXGG---------------
Mflv_5091|M.gilvum_PYR-GCK --------------------GQGGTGGTGGQGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------GTGGTGGTGGQGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155 TIVAYNVVQANPQASGTATDGHGGSGINGGHGGNG---------------
MUL_4367|M.ulcerans_Agy99 --------------------GVNGSGGAGGAGGAG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------NAAVGGVLNTGVSG---------------
MAV_4827|M.avium_104 --------------------PVAAPLPAAPPPAAP---------------
Mb3537|M.bovis_AF2122/97 PQAATGTAGSAGDPTGGNGGPGTPGSPMVAPPPPTPITQVQQGGDGGAGG
Rv3507|M.tuberculosis_H37Rv PQAATGTAGSAGDPTGGNGGPGTPGSPMVAPPPPTPITQVQQGGDGGAGG
MMAR_4995|M.marinum_M PQATAGNPGGSG-ITGEIGGSGTNGS-----PATLPTTQVQQGGDGGAGG
TH_3810|M.thermoresistible__bu -------------------------------------------GVGAAVR
Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------GQGTIEA
MUL_4367|M.ulcerans_Agy99 -------------------------------------------GTGGAGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------AIGGSSH
MAV_4827|M.avium_104 -------------------------------------------PLPEAPP
Mb3537|M.bovis_AF2122/97 TGSTNANDGTATGGKGGEGGVGSILGGPGGNGGTGGNASATGTNGVANAG
Rv3507|M.tuberculosis_H37Rv TGSTNANDGTATGGKGGEGGVGSILGGPGGNGGTGGNASATGTNGVANAG
MMAR_4995|M.marinum_M TGTNAANNEVATGGEGGTGGTG-SAGGPGGDGGVGGDASETGTDGVAVGG
TH_3810|M.thermoresistible__bu SG---------------NGVFS----GGGGTPSAG---------------
Mflv_5091|M.gilvum_PYR-GCK TG--------GTGGAGGDGGLG----GLGGFGGSG---------------
Mvan_1264|M.vanbaalenii_PYR-1 TG--------GTGGAGGDGGLG----GLGGFGGVG---------------
MSMEG_0868|M.smegmatis_MC2_155 NGPSAVASGIGAGGNGGDGIDG----GLGGNGGDG---------------
MUL_4367|M.ulcerans_Agy99 SG-------VPASVDGGDGGAG----GAGGAAGTG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VG---------GAINESLGGSG----SVGGSTAVG---------------
MAV_4827|M.avium_104 IP-------AAPPVVPVPVVVPPVPVPVPVRIPVP---------------
Mb3537|M.bovis_AF2122/97 NGGKGGDGGQFGAGGNGGAGGSVTDGSAGSTAGNGGNGGNATNGTIAGQP
Rv3507|M.tuberculosis_H37Rv NGGKGGDGGQFGAGGNGGAGGSVTDGSAGSTAGNGGNGGNATNGTIAGQP
MMAR_4995|M.marinum_M QGGQGGAGGQFGGGGNGGDGGNVTAGSAGSTAGNGGNGGNANNGTIEGSP
TH_3810|M.thermoresistible__bu --FGVPTTIQFPAGSCTSRAVSREG------------------------I
Mflv_5091|M.gilvum_PYR-GCK --GTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 --VVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
MUL_4367|M.ulcerans_Agy99 --GSGGSAGNTGAGGAGGAGGAGGSAASTGVNGDGGAGG----AGGVGGL
MLBr_01183|M.leprae_Br4923 ----MPLFLNAEPQALTAAANTLEG------------------------L
MAB_4284c|M.abscessus_ATCC_199 --GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG--------STA
MAV_4827|M.avium_104 ---DPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVG--------GTV
.
Mb3537|M.bovis_AF2122/97 AGGNGSAGGKGGDGGNIAAGATGTAGNGGNGGNGNDGAVNAGTGGSGGNG
Rv3507|M.tuberculosis_H37Rv AGGNGSAGGKGGDGGNIAAGATGTAGNGGNGGNGNDGAVNAGTGGSGGNG
MMAR_4995|M.marinum_M AGGNGSAGGDGGDGGDVASGATGTAGTGGTGGAGNDGTINAGTGGNGGAG
TH_3810|M.thermoresistible__bu MPSSRAASARAG--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------------------AQGATG
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------------------AQGATG
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGG------------NALVMAAGTTG
MUL_4367|M.ulcerans_Agy99 GGDSAATAGGGGAGGDGGKGGAGGAG----------------VNGVGGGD
MLBr_01183|M.leprae_Br4923 SAATVASNAAAAQ-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTGVGGGVSTGVGVGSHVGGG------------------------
MAV_4827|M.avium_104 PQSPPQHQTPPGEGTPPKPDGPGNYG--------------------GGHV
.
Mb3537|M.bovis_AF2122/97 GNAGGGGANGGDGGAGGAGGAGGRGGKGIDGGFGGDGGNGGSNNGTGAGG
Rv3507|M.tuberculosis_H37Rv GNAGGGGANGGDGGAGGAGGAGGRGGKGIDGGFGGDGGNGGSNNGTGAGG
MMAR_4995|M.marinum_M GRAGSGGANGGNGGTGGTGGDGGKGGGGAVGGSGGDGGDGGINNGAGANG
TH_3810|M.thermoresistible__bu -AACASSTSRSRRSFCCSRA------------------------------
Mflv_5091|M.gilvum_PYR-GCK -ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-
Mvan_1264|M.vanbaalenii_PYR-1 -ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-
MSMEG_0868|M.smegmatis_MC2_155 VATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAG
MUL_4367|M.ulcerans_Agy99 GGKGGTGGAGGAGGAGSDGIIPSNGGLGGNGGNGGNGGQAFGDGVGGAGG
MLBr_01183|M.leprae_Br4923 LTTEIAPPAADDVSILLAHFFSGHG-------------RQYQAHASQGAT
MAB_4284c|M.abscessus_ATCC_199 -ISESLGGSGSVGGSTAVGGGAHTG------------VGGGVNTGVGVGS
MAV_4827|M.avium_104 PTPGAGGSGGSGGGHVPTPGAGGSG--------------GSGGGHVPTPG
.
Mb3537|M.bovis_AF2122/97 NGGNGGTGGVGSVGAAGGDGGNGGTGGFAGFGG-TAGNGGSGGTGGAGGD
Rv3507|M.tuberculosis_H37Rv NGGNGGTGGVGSVGAAGGDGGNGGTGGFAGFGG-TAGNGGSGGTGGAGGD
MMAR_4995|M.marinum_M NGGGGGTGGTGSIGAAGGNGGQGGSGGAAGSGGGTAGNGGAGGVGGAGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGG
Mvan_1264|M.vanbaalenii_PYR-1 NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGG
MUL_4367|M.ulcerans_Agy99 IGGKGGNAAIGTIVINGGVGGAGG-----SGGLGGATEDGVGGVG-CAGG
MLBr_01183|M.leprae_Br4923 NHQDLIQSLLTSSSAYAG--------------TETANHDSL---------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGG------GAHTSAINDALGGSGSVGGS
MAV_4827|M.avium_104 TGGPGGTGGSGGGHVPTPGAGTPG-----------GSGGGHLPFPGAGST
Mb3537|M.bovis_AF2122/97 GGTGGGGGNGGTGVIAGGGGTGGNG---GASGAGGAGGTGGFAGNGNAGG
Rv3507|M.tuberculosis_H37Rv GGTGGDGGNG---VIAGGGGTGGNG---GASGAGGAGGTGGFAGNGNAGG
MMAR_4995|M.marinum_M GGVGGGGGDGGAGALAGTGGTGGSGGTGGASGAGGSGGGGGLSGSGQSGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAGG-----------AGGEGGEGG-DGGKGGAGAE--------GGAGG
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG-----------AGGEGGEGG-AGGAGGDGSE--------GGAGG
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGNTSVWKSGGQTADGEHNTGG-NGGNGGDGSEPGPGGNGAGGAGG
MUL_4367|M.ulcerans_Agy99 AGGNGGRGDMLFTVGGSGGTGGDGGG-GGSASGSGTGGSGGTGGVGGIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTSAINESMNSSINASHSSSMNESFG-----------------
MAV_4827|M.avium_104 PGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLG-------------
Mb3537|M.bovis_AF2122/97 NGG----TGGASEDGDNGNAGSGATGGTGGNGGTGGDGGAAGLGGVA---
Rv3507|M.tuberculosis_H37Rv NGG----TGGASEDGDNGNAGSGATGGTGGNGGTGGDGGAAGLGGVA---
MMAR_4995|M.marinum_M NGG----TGGASQEGQDGQASTDSDGGAGGAGGTGGSGGAAGAGGQA---
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GG-----GAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD----
Mvan_1264|M.vanbaalenii_PYR-1 SG-----GAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-----
MSMEG_0868|M.smegmatis_MC2_155 NG-----GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP----
MUL_4367|M.ulcerans_Agy99 DGKLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTGAGGAPSDKGING
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-------
MAV_4827|M.avium_104 ---------GGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK--------
Mb3537|M.bovis_AF2122/97 ------
Rv3507|M.tuberculosis_H37Rv ------
MMAR_4995|M.marinum_M ------
TH_3810|M.thermoresistible__bu ------
Mflv_5091|M.gilvum_PYR-GCK ------
Mvan_1264|M.vanbaalenii_PYR-1 ------
MSMEG_0868|M.smegmatis_MC2_155 ------
MUL_4367|M.ulcerans_Agy99 EPGNPG
MLBr_01183|M.leprae_Br4923 ------
MAB_4284c|M.abscessus_ATCC_199 ------
MAV_4827|M.avium_104 ------