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MTTDVLAGADARLEVVSVASGRMRVHVSGFGVDAVRAVAIEEKVAKVTGVQAVQAYPRTASVVIWYSPQH CDTAEVLSAIADAEHVPAESVPARAPHSADVPVTGVVRTVIGGPALALFGLCRRLLGGSPDGDRPGDTVD GGSCGQGAVAACHSSPGQDSGGERRKWLRRVWLTWPLALLATASTMVFGAAPWAGWLAFAATVPVQFVAG WPILKAAAQQARALSANMDTLIALGTLTAFGYSTYQLFAGGPLFFDTAALIIAFVVLGRYFEARATGKTS EAISKLLEMGAKEATLLVDDQELLVPVDQVRVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVE KTVGDRVAGATVNTDGLLTVRATAVGADTALAQIVRLVEQAQGGKAPVQRLADRVSAVFVPVVVGVAAAT FVGWSLIAADPVGGMTAAVAVLIIACPCALGLATPTAITVGTGRGAEMGILVKGGEVLEASKKIDTVVFD KTGTLTRAQMRLTDVIAGKRRQPDPVLRIAAAVESGSEHPIGAAIVAGARERGLEIPSATGFANLAGHGV RAEVNGKPVLVGRRKLVDESDLVLPDHLAAAAAELEQQGRTAVFVGQDDQVVGVLAVADTVKDDAIEVVR RLHAIGLKVAMITGDNARTAAAIAQQVGIDQVLAEVLPADKVTEIRRLQNQGQVVAMVGDGVNDAPALVQ ADLGIAIGTGTDVAIEASDITLMSGQLDGVVRAIGLSRQTLRTIYQNLGWAFGYNTAAIPLAALGLLNPV IAGAAMGLSSVSVVTNSLRLRRFGRDAQQQPERHTAVAPIRT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1431 | zntA | - | 100% (812) | cation transport ATPase, ZntA |
M. marinum M | MMAR_2536 | - | 0.0 | 81.14% (774) | metal cation transporter p-type ATPase |
M. marinum M | MMAR_4876 | ctpV | 0.0 | 78.18% (802) | metal cation transporter p-type ATPase, CtpV |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0994 | ctpV | 0.0 | 81.83% (776) | metal cation transporter P-type ATPase CtpV |
M. gilvum PYR-GCK | Mflv_2244 | - | 0.0 | 53.11% (659) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv0969 | ctpV | 0.0 | 81.96% (776) | metal cation transporter P-type ATPase CtpV |
M. leprae Br4923 | MLBr_01987 | ctpA | 1e-146 | 46.74% (629) | putative cation-transporting ATPase |
M. abscessus ATCC 19977 | MAB_3984c | - | 1e-154 | 45.89% (717) | putative metal transporter ATPase |
M. avium 104 | MAV_5246 | - | 1e-162 | 48.68% (680) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5014 | - | 0.0 | 53.76% (651) | copper-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_4361 | - | 1e-178 | 46.79% (780) | PUTATIVE heavy metal translocating P-type ATPase |
M. ulcerans Agy99 | MUL_0423 | ctpV | 0.0 | 78.59% (780) | metal cation transporter p-type ATPase, CtpV |
M. vanbaalenii PYR-1 | Mvan_4449 | - | 1e-180 | 53.30% (651) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0994|M.bovis_AF2122/97 ----------------------MRVCVTGFNVDAVRAVAIEETVSQVTGV Rv0969|M.tuberculosis_H37Rv ----------------------MRVCVTGFNVDAVRAVAIEETVSQVTGV MMAR_1431|M.marinum_M MTTDVLAGADARLEVVSVASGRMRVHVSGFGVDAVRAVAIEEKVAKVTGV MUL_0423|M.ulcerans_Agy99 ----------------------MRVHANGFAIDATRAAAIEESVGRVGGV Mflv_2244|M.gilvum_PYR-GCK ---------------------------------------MNTLELSIGGM Mvan_4449|M.vanbaalenii_PYR-1 ---------------------------------------MNTIELSIGGM MSMEG_5014|M.smegmatis_MC2_155 -----------------------------------MTTATGHVELQIGGM TH_4361|M.thermoresistible__bu ----------------------------------MNTGGMNTVTLTVGGM MAV_5246|M.avium_104 --------------------MSTPPRHIDEGTFPDHTASTARIELEITGM MAB_3984c|M.abscessus_ATCC_199 --------------------------------METTNTGMETTDLRLHGM MLBr_01987|M.leprae_Br4923 -------------------------------------------------M : Mb0994|M.bovis_AF2122/97 HAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAG Rv0969|M.tuberculosis_H37Rv HAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAG MMAR_1431|M.marinum_M QAVQAYPRTASVVIWYSPQHCDTAEVLSAIADAEHVPAESVPARAPHSAD MUL_0423|M.ulcerans_Agy99 RAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAARVAG Mflv_2244|M.gilvum_PYR-GCK TCASCAARVEKKLNKLD----GVTATVNYATEKARVEFGDNVSTDQLVSA Mvan_4449|M.vanbaalenii_PYR-1 TCASCAARVEKKLNKLD----GVTATVNFATEKARVAFGDEVSPGQLVSA MSMEG_5014|M.smegmatis_MC2_155 TCASCAARIERKLNKLD----GVTASVNYATEKASVEVAGEVSPETLIEV TH_4361|M.thermoresistible__bu TCASCAARVEKRLNRID----GVVATVNFATEQATVRYPDHVDPADLIAA MAV_5246|M.avium_104 TCASCAARIEKKLNKLD----GVTATVNYATEKAAVSAPASYDPQTLITE MAB_3984c|M.abscessus_ATCC_199 TCASCASRVEKGLNKIT----GVNARVNLALESARVEHDGSVTGEDLVKA MLBr_01987|M.leprae_Br4923 RAPNGWNNLPNKLSDFS-------TLVNSATRVAAINLSEVTQTAEVCEA . . : :. Mb0994|M.bovis_AF2122/97 VRGVGVVRKITGG--------IRRMLSR---------PPGVDKPLKASRC Rv0969|M.tuberculosis_H37Rv VRGVGVVRKITGG--------IRRMLSR---------PPGVDKPLKASRC MMAR_1431|M.marinum_M VPVTGVVRTVIGGPALALFGLCRRLLGG---------SPDGDRPGDTVDG MUL_0423|M.ulcerans_Agy99 IADGGVVGRVIGG-------LARALLGMRTDDNDDDPPPEIARLRAALDR Mflv_2244|M.gilvum_PYR-GCK VESAGYQAALPEP------------------------------------- Mvan_4449|M.vanbaalenii_PYR-1 VESAGYQAELPER------------------------------------- MSMEG_5014|M.smegmatis_MC2_155 VETAGYTAHLPAP------------------------------------- TH_4361|M.thermoresistible__bu IEATGYTASLPAPQ-------------------------------RDTGG MAV_5246|M.avium_104 IENAGYAAAVATP------------------------------------- MAB_3984c|M.abscessus_ATCC_199 VESVGYTAQVVGGS-------------------------------HQDAH MLBr_01987|M.leprae_Br4923 VRRAALCT------------------------------------------ : . Mb0994|M.bovis_AF2122/97 GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLL-ALGSSMFFGA Rv0969|M.tuberculosis_H37Rv GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLL-ALGSSMFFGA MMAR_1431|M.marinum_M GSCGQGAVAACHSSPGQDSGGERRKWLRRVWLTWPLALL-ATASTMVFGA MUL_0423|M.ulcerans_Agy99 IGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLL-ASGLTMFFGA Mflv_2244|M.gilvum_PYR-GCK --PNPPD-----VEPADPTAALRRRLIICVALSVPVIAM-AMAPPLQFTY Mvan_4449|M.vanbaalenii_PYR-1 --PDEPA-----EPTDDPTAALKRRLLICVALSVPVIAM-AMVPVLQFTY MSMEG_5014|M.smegmatis_MC2_155 --PQPETGGTEQDPEDRATDALRTRLLVSAVLTVPVIAM-AMVPALQFTN TH_4361|M.thermoresistible__bu A-PAGAATGAAGDDHDAEAERWRRRLTISAALSIPVVVL-SMIPALQFTH MAV_5246|M.avium_104 ---SPPR-------DDPELASLRRRLVTAIALAGPVIAV-AMIPALQFQH MAB_3984c|M.abscessus_ATCC_199 AGDHDGHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVI-SMAMPLHFSG MLBr_01987|M.leprae_Br4923 ---DGGEALQRRQADADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTH * *: : : Mb0994|M.bovis_AF2122/97 YPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAF Rv0969|M.tuberculosis_H37Rv YPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAF MMAR_1431|M.marinum_M APWAGWLAFAATVPVQFVAGWPILKAAAQQARALSANMDTLIALGTLTAF MUL_0423|M.ulcerans_Agy99 YPWAGWLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAF Mflv_2244|M.gilvum_PYR-GCK W---QWLSLTLAAPVVVWGAWPFHRATWANLRHGTATMDTLISVGTLAAF Mvan_4449|M.vanbaalenii_PYR-1 W---QWLSLTLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAAL MSMEG_5014|M.smegmatis_MC2_155 W---QWLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAF TH_4361|M.thermoresistible__bu W---QWLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAY MAV_5246|M.avium_104 W---HWAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAF MAB_3984c|M.abscessus_ATCC_199 W---EILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAY MLBr_01987|M.leprae_Br4923 FPGWEWMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAAT : : *: . *: : : : :.*:**:: * :* Mb0994|M.bovis_AF2122/97 VYSTYQLFAGGP---------------------------LFFDTSALIIA Rv0969|M.tuberculosis_H37Rv VYSTYQLFAGGP---------------------------LFFDTSALIIA MMAR_1431|M.marinum_M GYSTYQLFAGGP---------------------------LFFDTAALIIA MUL_0423|M.ulcerans_Agy99 IYSTYQLFAGGP---------------------------LFFDTAALIIA Mflv_2244|M.gilvum_PYR-GCK GWSIYALFWGTAGVPGMTHPFELTI------ARTDGSGNIYLEAAAGVTT Mvan_4449|M.vanbaalenii_PYR-1 GWSIYALFWGTAGIPGMTHPFELTI------ARTDGTSNIYLEAAAGVTT MSMEG_5014|M.smegmatis_MC2_155 GWSLYALFWGTAGVPGMTHPFSLVG------SRTDGAGNIYLEVAAGVTT TH_4361|M.thermoresistible__bu LWSLWALFFTAAGMPGMTMTFTLLP------ADT-GEPHIYLEVAAAVTT MAV_5246|M.avium_104 LWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTL MAB_3984c|M.abscessus_ATCC_199 LWSLWVLFANAG--------------------HTHGDVHVYFEVVAAVTV MLBr_01987|M.leprae_Br4923 IWSLYTVFGHHQSTEHRGVWRALLG-----------SDAIYFEVAAGITV :* : :. ::::. * : Mb0994|M.bovis_AF2122/97 FVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQVQV Rv0969|M.tuberculosis_H37Rv FVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQVQV MMAR_1431|M.marinum_M FVVLGRYFEARATGKTSEAISKLLEMGAKEATLLV-DDQELLVPVDQVRV MUL_0423|M.ulcerans_Agy99 FVVLGRYFEATAHGKTREAISKLLDMGAKETRLIV-DGEEHLVPVDRVQV Mflv_2244|M.gilvum_PYR-GCK FILAGRYFEARAKRRAGAALRALLELGVRDVTVRR-GAAEHRIPIDQLRV Mvan_4449|M.vanbaalenii_PYR-1 FILAGRYFEARAKRRAGAALRALLELGAREVTVRR-GGAEQRIPIEQLVI MSMEG_5014|M.smegmatis_MC2_155 FILAGRYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGV TH_4361|M.thermoresistible__bu FIIAGRYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHV MAV_5246|M.avium_104 FVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAV MAB_3984c|M.abscessus_ATCC_199 FLLAGRFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAV MLBr_01987|M.leprae_Br4923 FVLAGKYYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNE *:: *:. : : *: * :...:. : * :* .: Mb0994|M.bovis_AF2122/97 GDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATV Rv0969|M.tuberculosis_H37Rv GDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATV MMAR_1431|M.marinum_M GDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTVGDRVAGATV MUL_0423|M.ulcerans_Agy99 GDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDWVAGATV Mflv_2244|M.gilvum_PYR-GCK DDEFVVRPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPGDRVVGATV Mvan_4449|M.vanbaalenii_PYR-1 GDEFVVRPGEKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATV MSMEG_5014|M.smegmatis_MC2_155 GDEFVVRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATV TH_4361|M.thermoresistible__bu GDVFVVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATV MAV_5246|M.avium_104 GDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTV MAB_3984c|M.abscessus_ATCC_199 GDEFVVRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYV MLBr_01987|M.leprae_Br4923 QQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTV : . ****: :..** : * :::. : :***: * . * * *. * Mb0994|M.bovis_AF2122/97 NLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPA Rv0969|M.tuberculosis_H37Rv NLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPA MMAR_1431|M.marinum_M NTDGLLTVRATAVGADTALAQIVRLVEQAQGGKAPVQRLADRVSAVFVPV MUL_0423|M.ulcerans_Agy99 NTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPV Mflv_2244|M.gilvum_PYR-GCK NVDGRLVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVPV Mvan_4449|M.vanbaalenii_PYR-1 NVDGRLVVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPI MSMEG_5014|M.smegmatis_MC2_155 NVGGRLVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPI TH_4361|M.thermoresistible__bu NVGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPI MAV_5246|M.avium_104 NAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPV MAB_3984c|M.abscessus_ATCC_199 NTHGRIVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPV MLBr_01987|M.leprae_Br4923 VLNGRLIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPC * : *.* :* :* ** :.::* ** :* .******::.**** Mb0994|M.bovis_AF2122/97 VIGVAVATFA-GWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVG Rv0969|M.tuberculosis_H37Rv VIGVAVATFA-GWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVG MMAR_1431|M.marinum_M VVGVAAATFV-GWSLIAADPVGGMTAAVAVLIIACPCALGLATPTAITVG MUL_0423|M.ulcerans_Agy99 VVRIAAATFA-GWTLLAANPVAGMTAAVSVLIIACPYALGLATPTAIIVG Mflv_2244|M.gilvum_PYR-GCK VLGLAVATLG-FWIGSGYPVAAAFTAAVAVLIIACPCALGLATPMALMVG Mvan_4449|M.vanbaalenii_PYR-1 VIALSVATLG-FWIGSGFPVAAAFTAAVAVLIIACPCALGLATPTALMVG MSMEG_5014|M.smegmatis_MC2_155 VIALAVATLG-FWLGTGGSVAAAFTAAVAVLIIACPCALGLATPTALLVG TH_4361|M.thermoresistible__bu VIALSALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVG MAV_5246|M.avium_104 VLLLAVATLA-GWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVG MAB_3984c|M.abscessus_ATCC_199 VLAISALTFV-AWAALGNSLASAFTAAVAVLIIACPCALGLATPTAILVG MLBr_01987|M.leprae_Br4923 VFAVAALTAV-GWLIAGSGPDRVFSAAIAVLVIACPCALGLATPTAMMVA *. ::. * ::**::**:**** ******* *: *. Mb0994|M.bovis_AF2122/97 TGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRR Rv0969|M.tuberculosis_H37Rv TGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRR MMAR_1431|M.marinum_M TGRGAEMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMRLTDVIAGKRR MUL_0423|M.ulcerans_Agy99 TGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDVIAGKRR Mflv_2244|M.gilvum_PYR-GCK TGRGAQLGILIKGPEVLESTRRVDTVIVDKTGTVTTGDMTLVDVFAADGE Mvan_4449|M.vanbaalenii_PYR-1 TGRGAQLGILIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE MSMEG_5014|M.smegmatis_MC2_155 TGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE TH_4361|M.thermoresistible__bu TGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL MAV_5246|M.avium_104 TGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT MAB_3984c|M.abscessus_ATCC_199 TGRGAQLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGS MLBr_01987|M.leprae_Br4923 SGRGAQLGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGW :**.*::*:*:** : :* : :**::.*****:* . : : * . Mb0994|M.bovis_AF2122/97 ---QPNQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGH Rv0969|M.tuberculosis_H37Rv ---QPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGH MMAR_1431|M.marinum_M ---QPDPVLRIAAAVESGSEHPIGAAIVAGARERGLEIPSATGFANLAGH MUL_0423|M.ulcerans_Agy99 ---QPDVVLRIAAAVESGSEHPIGAAIVAGARERELEVPPATEFTNLAGH Mflv_2244|M.gilvum_PYR-GCK ---QPDEVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDGFANLRGL Mvan_4449|M.vanbaalenii_PYR-1 ---QPDEVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGL MSMEG_5014|M.smegmatis_MC2_155 ---DRDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGL TH_4361|M.thermoresistible__bu ---SETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGN MAV_5246|M.avium_104 ---DRATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGG MAB_3984c|M.abscessus_ATCC_199 GVADADEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGV MLBr_01987|M.leprae_Br4923 ---QANEVLQMAATVESASEHAVALAIAASTTHR----EPVANFRAVPGH . :*: *.::* ***.:. *:. : * * Mb0994|M.bovis_AF2122/97 GVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQD Rv0969|M.tuberculosis_H37Rv GVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQD MMAR_1431|M.marinum_M GVRAEVNGKPVLVGRRKLVDESDLVLPDHLAAAAAELEQQGRTAVFVGQD MUL_0423|M.ulcerans_Agy99 GVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVYVGQD Mflv_2244|M.gilvum_PYR-GCK GVEGDVEGRRLTLGRLRLLSDRSFEIPDDLASAVARAEAGGSTAVTVGWD Mvan_4449|M.vanbaalenii_PYR-1 GVSGQVDGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWD MSMEG_5014|M.smegmatis_MC2_155 GVQGTVEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWD TH_4361|M.thermoresistible__bu GVSGRVDGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVD MAV_5246|M.avium_104 GVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWD MAB_3984c|M.abscessus_ATCC_199 GVSGVVDGQEVSI----------------------EAIEGQNTTAAVSWG MLBr_01987|M.leprae_Br4923 GVSGTVAERAVRVGKPSWIASR--CNSTTLVTARRNAELRGETAVFVEID ** . * : : * . * . Mb0994|M.bovis_AF2122/97 GQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVG Rv0969|M.tuberculosis_H37Rv GQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVG MMAR_1431|M.marinum_M DQVVGVLAVADTVKDDAIEVVRRLHAIGLKVAMITGDNARTAAAIAQQVG MUL_0423|M.ulcerans_Agy99 GQVVGVLAVADTVKDDAADVVSQLHAMGLQVALITGDNARTAAAIAAQVG Mflv_2244|M.gilvum_PYR-GCK GRARGVLMVADAVKPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVG Mvan_4449|M.vanbaalenii_PYR-1 GQARGVLMVADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVG MSMEG_5014|M.smegmatis_MC2_155 GTARGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVG TH_4361|M.thermoresistible__bu GRIAGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVG MAV_5246|M.avium_104 GRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELG MAB_3984c|M.abscessus_ATCC_199 GLRRGEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVG MLBr_01987|M.leprae_Br4923 GEQCGVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIG . * : ::*:** : .: : * ::**** * * .:* Mb0994|M.bovis_AF2122/97 IE--KVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIA Rv0969|M.tuberculosis_H37Rv IE--KVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIA MMAR_1431|M.marinum_M ID--QVLAEVLPADKVTEIRRLQNQGQVVAMVGDGVNDAPALVQADLGIA MUL_0423|M.ulcerans_Agy99 ID--RVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIA Mflv_2244|M.gilvum_PYR-GCK ID--EVVAGVLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMA Mvan_4449|M.vanbaalenii_PYR-1 ID--EVIAGVLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLA MSMEG_5014|M.smegmatis_MC2_155 ID--DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLS TH_4361|M.thermoresistible__bu ID--DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLA MAV_5246|M.avium_104 IG--EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLA MAB_3984c|M.abscessus_ATCC_199 IAAGDVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMA MLBr_01987|M.leprae_Br4923 ID--EVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMA * * : * :*. : :*: *: ***:***:**..**. **:*:: Mb0994|M.bovis_AF2122/97 IGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNT Rv0969|M.tuberculosis_H37Rv IGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNT MMAR_1431|M.marinum_M IGTGTDVAIEASDITLMSGQLDGVVRAIGLSRQTLRTIYQNLGWAFGYNT MUL_0423|M.ulcerans_Agy99 IGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNT Mflv_2244|M.gilvum_PYR-GCK MGSGTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNV Mvan_4449|M.vanbaalenii_PYR-1 MGSGTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNV MSMEG_5014|M.smegmatis_MC2_155 MGTGTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNV TH_4361|M.thermoresistible__bu IGTGTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNV MAV_5246|M.avium_104 MGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNL MAB_3984c|M.abscessus_ATCC_199 MGTGTDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNT MLBr_01987|M.leprae_Br4923 IGRGTDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNI :* ***.** *.*: :: . * . :: *. *: ** *: ***.** Mb0994|M.bovis_AF2122/97 AAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA------ Rv0969|M.tuberculosis_H37Rv AAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA------ MMAR_1431|M.marinum_M AAIPLAALGLLNPVIAGAAMGLSSVSVVTNSLRLRRFGRDAQQQPERHTA MUL_0423|M.ulcerans_Agy99 AAIPLAALGVLNPVVAGAAMGLSSVSVVTNSLRLRRFGRDV--------- Mflv_2244|M.gilvum_PYR-GCK AALPLAAAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR--------- Mvan_4449|M.vanbaalenii_PYR-1 AALPLAAAGLLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR--------- MSMEG_5014|M.smegmatis_MC2_155 AALPLAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR------------ TH_4361|M.thermoresistible__bu AALPLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR--------- MAV_5246|M.avium_104 AAIPLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA------ MAB_3984c|M.abscessus_ATCC_199 AAIPLAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR------------ MLBr_01987|M.leprae_Br4923 AAIPIAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRT **:*:** * ***::*****.:**. ** *****: * Mb0994|M.bovis_AF2122/97 ---------------------------------------- Rv0969|M.tuberculosis_H37Rv ---------------------------------------- MMAR_1431|M.marinum_M VAPIRT---------------------------------- MUL_0423|M.ulcerans_Agy99 ---------------------------------------- Mflv_2244|M.gilvum_PYR-GCK ---------------------------------------- Mvan_4449|M.vanbaalenii_PYR-1 ---------------------------------------- MSMEG_5014|M.smegmatis_MC2_155 ---------------------------------------- TH_4361|M.thermoresistible__bu ---------------------------------------- MAV_5246|M.avium_104 ---------------------------------------- MAB_3984c|M.abscessus_ATCC_199 ---------------------------------------- MLBr_01987|M.leprae_Br4923 VKRWRCPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR