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MSFVIVAPEALMSVASEVAGIGSALNAANAAAAAPTTGVLAAAADEVSAAMAALFGAHAQEYQRLSAQAA GFHAQFVQALNAGVNSYASAEAANASPLQAVEQQVLGLINGPAQTLLGRPLIGNGADGAPGTGQPGGPGG LLWGNGGNGGSGVAGVGGPGGSGGAAGLFGHGGNGGAGGSNAAGAGGVGGAGGAGWLVGNGGAGGFGGVG TTVSGNGGAGGAAGAFGNGGVGGAGGAAVIGGLPGNGGAGGNAGLIGAGGDGGVGGVGAPGTNGMNPPPN QTSQAANGSPGANNGAGSGGAGLPGNPGAVPGRAGGAGGLGGSGSDTSEGPVTGGNGGNGGDGGPGAPGG NGAPGGIGVNTGTGWAYGGNGGNGGDGGAGARGGDGGNGGNGLALNGGNGIGGNGGAGGRGGTGAAGGNG GIGGGATGTLTFFGSGGDGGPGGAGANTAGTGGVGGVGGAGGQGGLLFGDGGNGGAGGAGGIGGTGASGG AGGKGGSGLVGGDGGNGGAGGAGGNGGKGGAGGAGGGAGMFSQPGVHGAGGTGGQGGAGGAGGAGGAAGA GTVVAGNPGDPGGFGAAGADGLPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3621c | PE_PGRS58 | - | 100% (584) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | e-168 | 50.58% (686) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1275c | PE_PGRS23 | e-168 | 54.15% (602) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-115 | 50.80% (502) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3590c | PE_PGRS58 | 0.0 | 100.00% (584) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 6e-13 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-51 | 36.30% (449) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4149 | - | 1e-170 | 54.43% (621) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 6e-26 | 36.59% (276) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-90 | 36.93% (685) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 9e-44 | 39.46% (332) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 1e-156 | 50.84% (653) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-113 | 47.86% (514) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
Mb3621c|M.bovis_AF2122/97 --------------MS-FVIVAPEALMSVASEVAGIGSALNAANAAAAAP
Rv3590c|M.tuberculosis_H37Rv --------------MS-FVIVAPEALMSVASEVAGIGSALNAANAAAAAP
MLBr_01183|M.leprae_Br4923 --------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQL
MAV_1346|M.avium_104 --------------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAP
MMAR_4149|M.marinum_M --------------MS-FVVVSPEVLAVAGRDLASIGSAISQANVAAAAP
MUL_0572|M.ulcerans_Agy99 --------------MS-YVVAIPDMLASAAADVAGIGSSVGAANTAAVGA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
MAB_4284c|M.abscessus_ATCC_199 FRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQS
. .
Mb3621c|M.bovis_AF2122/97 TTGVLAAAADEVSAAMAALFGAHAQEYQRLS----------------AQA
Rv3590c|M.tuberculosis_H37Rv TTGVLAAAADEVSAAMAALFGAHAQEYQRLS----------------AQA
MLBr_01183|M.leprae_Br4923 TTEIAPPAADDVSILLAHFFSGHGRQYQAHA----------------SQG
MAV_1346|M.avium_104 TTSIAPAAADEVSALQAAQFSAYGTWYQQVS----------------AQA
MMAR_4149|M.marinum_M TMGALAAGADEVSAAVAAVFSGHAQAYQALG----------------AQV
MUL_0572|M.ulcerans_Agy99 TTGVMAAADDEVSVAIAALFSGHGQAYQAIS----------------AQA
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR----------------TTD
MAB_4284c|M.abscessus_ATCC_199 QWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP---------------SLL
.
Mb3621c|M.bovis_AF2122/97 AGFHAQFVQALNAGVNSYASAEAANASPLQAVEQQVLG------------
Rv3590c|M.tuberculosis_H37Rv AGFHAQFVQALNAGVNSYASAEAANASPLQAVEQQVLG------------
MLBr_01183|M.leprae_Br4923 ATNHQDLIQSLLTSSSAYAGTETAN-------------------------
MAV_1346|M.avium_104 KAIHQTLVQNLDTNADSYGATEAANRVNTSAAALQGL-------------
MMAR_4149|M.marinum_M AAFHDQLVTALDAAAGKYASAEVANASPLQA----VLD------------
MUL_0572|M.ulcerans_Agy99 AAFHDQFLRALTGAGGAYAAAEAANASPLQAAEQEVLA------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu NNALDGGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG--------------
MAB_4284c|M.abscessus_ATCC_199 SPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN------------
.
Mb3621c|M.bovis_AF2122/97 -LINGPAQTLLGRPLIGNGADGAPGTGQPGGPGGLLWGNGGNGGSGVAGV
Rv3590c|M.tuberculosis_H37Rv -LINGPAQTLLGRPLIGNGADGAPGTGQPGGPGGLLWGNGGNGGSGVAGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------APNVI--------PNAAPAADPP---------------------
MMAR_4149|M.marinum_M -VVNAPAQALLGRPLIGNGDDGVAGTGQSGGDGGILYGNGGDGGSGASGQ
MUL_0572|M.ulcerans_Agy99 -VINAPTNALLGRPLIGNGTDGLAGTGAAGGAGGLLWGNGGNGGSGAAGQ
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------------------
MAB_4284c|M.abscessus_ATCC_199 --RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNS--------------
Mb3621c|M.bovis_AF2122/97 GGPGGSGGAAGLFGHGGNGGAGGSNAAGAGGVGGAGGAGWLVGNGGAGGF
Rv3590c|M.tuberculosis_H37Rv GGPGGSGGAAGLFGHGGNGGAGGSNAAGAGGVGGAGGAGWLVGNGGAGGF
MLBr_01183|M.leprae_Br4923 -------------------------------------------------H
MAV_1346|M.avium_104 ----------------------------------------------PAGT
MMAR_4149|M.marinum_M IGGTGGSAGLIGAGGTGGAGGLG-AAGGAGGNGGWLFGQGGAG---GIGG
MUL_0572|M.ulcerans_Agy99 AGGAGGAAGLIGTGGAGGMGGAGGGAGGMGGSGGWLLGNGGAGGAGGVGC
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------QGEDGE
MAB_4284c|M.abscessus_ATCC_199 GPIASGQGSTAVNGDVRDSNIINADHGSNVGVD-----------QSQTRV
Mb3621c|M.bovis_AF2122/97 GGVGTTVSGNGGAGGAAGAFGNGGVGGAGGAAVIG---------------
Rv3590c|M.tuberculosis_H37Rv GGVGTTVSGNGGAGGAAGAFGNGGVGGAGGAAVIG---------------
MLBr_01183|M.leprae_Br4923 DSL-----------------------------------------------
MAV_1346|M.avium_104 TSLGTSIGWAQNVGAAASDFITLGEGQFAPVPGAA---------------
MMAR_4149|M.marinum_M SGAAGGAGGNGG--WLYGDGGAGGQGGAAAESIN----------------
MUL_0572|M.ulcerans_Agy99 AGVSGGVGGTGGNAMLFGNGGAGGMGGAGADGAVGAAGTAGTSTSAGGVG
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu DGTGTGIGGRGGNG------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTN------
.
Mb3621c|M.bovis_AF2122/97 -------------GLPGNGGAGGNAGLIGAG-------GDGGVGGVGAPG
Rv3590c|M.tuberculosis_H37Rv -------------GLPGNGGAGGNAGLIGAG-------GDGGVGGVGAPG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------GIPN-----FNPGLTAAT-------TAG---------
MMAR_4149|M.marinum_M ------------DGSPGQGGNGGSAYLFGNG-------GSGGQGGTG--L
MUL_0572|M.ulcerans_Agy99 GAGWDATAAGVLAATGGDGGDSGGGGAGGNG-------GAGGAGGHGSAL
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ------------------GSSSGTHPMAEDG-------------------
MAB_4284c|M.abscessus_ATCC_199 -----------IGSGNTTNTEIGSHNQANIG-------------------
Mb3621c|M.bovis_AF2122/97 TNGMNPPPNQTSQAANGSPGANN---------------------------
Rv3590c|M.tuberculosis_H37Rv TNGMNPPPNQTSQAANGSPGANN---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----PPAPAAPAAAAGAPVLASM---------------------------
MMAR_4149|M.marinum_M AGADGVNYSNGTAG----PGAWGNNVTTSIG-------------------
MUL_0572|M.ulcerans_Agy99 FGADGANGNGGAGGAGGNPGAPGNGGTGGVGPDAATSGGMGGTGGDPGAV
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS-----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE-----------------------
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATG-------------------
TH_3810|M.thermoresistible__bu -----EHVKALDGRPGLDGG------------------------------
MAB_4284c|M.abscessus_ATCC_199 -TSTSAGGSAAVGGNAGLAGNAGLAG------------------------
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------DANGGNGGSG-----ADG------
MUL_0572|M.ulcerans_Agy99 GGRGNSGAAGGAGAVAGASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAI
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------VATGNTAIGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3621c|M.bovis_AF2122/97 -----GAGSGGAGLPGNPGAVPGRA-------------------------
Rv3590c|M.tuberculosis_H37Rv -----GAGSGGAGLPGNPGAVPGRA-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----GRGPSIGGLSVPPSWAP----------------------------
MMAR_4149|M.marinum_M GAGVTGGTGGVGGFANNEGSGDANG-------------------------
MUL_0572|M.ulcerans_Agy99 GNGGDGGHGGAGGFYGNGGAGGAGGNSAPGGGT-----------------
Mflv_5091|M.gilvum_PYR-GCK -AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD---
Mvan_1264|M.vanbaalenii_PYR-1 -AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN---
MSMEG_0868|M.smegmatis_MC2_155 AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV
TH_3810|M.thermoresistible__bu ----NGSHGGNGGHGGRGGFLG----------------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAGNAG-------------------------
Mb3621c|M.bovis_AF2122/97 ----------------GGAGGLGGSGSDTSEGPVTGGNGGNGGDGGP---
Rv3590c|M.tuberculosis_H37Rv ----------------GGAGGLGGSGSDTSEGPVTGGNGGNGGDGGP---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------------GGVAPAANATPAQLVGAGFTSAAPDTAP---
MMAR_4149|M.marinum_M -----------------GFGGTGGNGGAPGASGGEGGTGGVAIASGG---
MUL_0572|M.ulcerans_Agy99 ----------------GGNGGTGGDSGAMGSSGGRGGDGGVGTNGGAGGG
Mflv_5091|M.gilvum_PYR-GCK -------------------GGTGGAGGAGGTGG-TGGAGGTGG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGTGGNGGNGGTGG-TGGNGGTGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKA
TH_3810|M.thermoresistible__bu ------------------IGGSGGWGGHGGNGGDTDADGGNGG-------
MAB_4284c|M.abscessus_ATCC_199 ------------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG--
Mb3621c|M.bovis_AF2122/97 --------------------GAPGGNGAPGGIGVNTGTGWAYGGNGGNGG
Rv3590c|M.tuberculosis_H37Rv --------------------GAPGGNGAPGGIGVNTGTGWAYGGNGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------VTAVPGGVP---------------------
MMAR_4149|M.marinum_M --------------------NAYGGSGGTGGNGATG--ASGGTGGTGGT-
MUL_0572|M.ulcerans_Agy99 ----------GGNATSYGTANATGGAGGDGGTGSTGNGGSGGDGGNGGTG
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 NGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGG
TH_3810|M.thermoresistible__bu -----------------------------------------------DGG
MAB_4284c|M.abscessus_ATCC_199 ------------------LAGNAGLAGNAGLAGNAGLAGNAG--LAGNAG
Mb3621c|M.bovis_AF2122/97 DGGAGARGGDGGNGGNGLALNGGNGIGGNGGAGGRGGTG----------A
Rv3590c|M.tuberculosis_H37Rv DGGAGARGGDGGNGGNGLALNGGNGIGGNGGAGGRGGTG----------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------------------SMATAGRGGYG----------L
MMAR_4149|M.marinum_M -GGDGGHGGLLIGNGG---IGGIGGTGGVGGIGGTGGDG------GTGGV
MUL_0572|M.ulcerans_Agy99 HGGGGGPGGTAINYGAGDAFGGAAGKGGTGVVGGNGGSGGAAYNYGTGNA
Mflv_5091|M.gilvum_PYR-GCK TGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GT
MSMEG_0868|M.smegmatis_MC2_155 HGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGA
TH_3810|M.thermoresistible__bu NGGSAGRGGTGGLRGVFGIN------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAG---------NA
Mb3621c|M.bovis_AF2122/97 AGGNGGIGGG-----------ATGTLTFFGSGGDGGPGGAG---------
Rv3590c|M.tuberculosis_H37Rv AGGNGGIGGG-----------ATGTLTFFGSGGDGGPGGAG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GAPRYGVKPT-----------VMPKPAI----------------------
MMAR_4149|M.marinum_M GGSALNTGSG------------VADANIGGDGGDAGTGGDGGTGG-----
MUL_0572|M.ulcerans_Agy99 TGAGGSSGSGGAASVPNSASTATATSGSGGAGGDGTDGGNGGSGGFAF--
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEA
TH_3810|M.thermoresistible__bu ---GGNGRAG-----------------------------LGGRGXXXX--
MAB_4284c|M.abscessus_ATCC_199 AVAGNAAVAG-----------NAAVGGVLNTGVSGAIGGSSHVGGAIN--
Mb3621c|M.bovis_AF2122/97 -------------ANTAGTGGVGGVG------------------------
Rv3590c|M.tuberculosis_H37Rv -------------ANTAGTGGVGGVG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M ---------------VGGVGGSGGAG----GLLFGNGG------------
MUL_0572|M.ulcerans_Agy99 --------TFGTGNIIAGVGGGGGTGSTGVGGIGGSGGGADINNGAFTVV
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGQGG-LGGGGGTG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGQGG-LGGVGGTG-----------------
MSMEG_0868|M.smegmatis_MC2_155 LIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQA
TH_3810|M.thermoresistible__bu ---------------GGGVG------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------ESLGGSGSVGGSTAVG---------------------
Mb3621c|M.bovis_AF2122/97 ---GAGGQGGLLFGDGGNGGAG-------------GAGGIGGTGASGGAG
Rv3590c|M.tuberculosis_H37Rv ---GAGGQGGLLFGDGGNGGAG-------------GAGGIGGTGASGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M -DGGAGGDGGVGGT-GGIGGAG-------------GNGGVGGDGSSSGTG
MUL_0572|M.ulcerans_Agy99 PQGGAGGHGGDGATDGGAGGAGGFTEIDSSASVIAATGGAGGDGGSGGTG
Mflv_5091|M.gilvum_PYR-GCK ------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
Mvan_1264|M.vanbaalenii_PYR-1 ------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
MSMEG_0868|M.smegmatis_MC2_155 SGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDG
TH_3810|M.thermoresistible__bu ---------------------------------------AAVRSGNGVFS
MAB_4284c|M.abscessus_ATCC_199 ------GGAHTGVGGGVSTGVGVG-----------SHVGGGISESLGGSG
Mb3621c|M.bovis_AF2122/97 GKGGSGLVGGDGGNGGAGGA----------GGNGGKGGAGGAGG------
Rv3590c|M.tuberculosis_H37Rv GKGGSGLVGGDGGNGGAGGA----------GGNGGKGGAGGAGG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M AGGSGGDATDGG-TGGDGGS----------GGGFGTGGAGGTGG------
MUL_0572|M.ulcerans_Agy99 RGGTGGGGTGGGGTGGGGGVGINNGSGEAIGGAPGAGGTGAVGGDGGQGG
Mflv_5091|M.gilvum_PYR-GCK GLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1 GLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155 GLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
TH_3810|M.thermoresistible__bu GGGGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS---------
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG----
Mb3621c|M.bovis_AF2122/97 ------------GAGMFSQPGVHGAGGTGGQGGAG----------GAGGA
Rv3590c|M.tuberculosis_H37Rv ------------GAGMFSQPGVHGAGGTGGQGGAG----------GAGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------WLIGHSGTNGIGGTGGAG-------GAGAVGGDGGV
MUL_0572|M.ulcerans_Agy99 AAYSYGTGDATGSAGAAGTAGTTGVGGTGGAGGAAYTLNGASTATATGGI
Mflv_5091|M.gilvum_PYR-GCK GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155 QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
TH_3810|M.thermoresistible__bu -----ARAGAACASSTSRSRRSFCCSRA----------------------
MAB_4284c|M.abscessus_ATCC_199 ----STAVGGGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGGSTAV
Mb3621c|M.bovis_AF2122/97 GGAAGAGTVVAGNPGDPGGFG----------------AAGADGLPG----
Rv3590c|M.tuberculosis_H37Rv GGAAGAGTVVAGNPGDPGGFG----------------AAGADGLPG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M GGDPGVGTTYNGISGHNGVQG----------------GTGADGAAG----
MUL_0572|M.ulcerans_Agy99 GGNGGDGGTANGSNGGNGGAGGYASTTGTGTASVGNGGRGGDGTATVATG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGAHTSAINDALGGSGSVGG----------STAVGGGAHTSAINESMNS
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GTGGVGGNAHAPAGSPVPGVGGKGGNPGPGGKPGPNGADGIVV-------
Mflv_5091|M.gilvum_PYR-GCK SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAE
Mb3621c|M.bovis_AF2122/97 --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK G-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155 GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HH------------------------------------------------
Mb3621c|M.bovis_AF2122/97 -----------------------------------
Rv3590c|M.tuberculosis_H37Rv -----------------------------------
MLBr_01183|M.leprae_Br4923 -----------------------------------
MAV_1346|M.avium_104 -----------------------------------
MMAR_4149|M.marinum_M -----------------------------------
MUL_0572|M.ulcerans_Agy99 -----------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 SGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------