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TRVEDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSDMTGALGAIASMWLGVHQVPISIGG RELGVMPLFPALLMVWGTARTTALATSPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTP SALRAFVSVLAVHAIGAGLGVWSRVGRRALAVSPLPNWLGDSLRAAAAGVLALLGLSGLVTAGSLVVHWA TMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVGASAHIGFATFSAFTVFGGDIPAVPILAAAPT PLLGPVWVALLIIGASSGVAVGQQCARRPLPPLPAMGKLLAAALVGALAMALLGYGGSGKLGNFGAVGVD EGALLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPAPPVEADVDEPIHEPVDEPFVPLFDQDAPLGDM TSREPVAPGGDDADVPPAAPDEADWSDGPDRPDGPDRQDGPDASHPPEHLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4544 | - | - | 100% (472) | integral membrane protein |
| M. marinum M | MMAR_0771 | mmpL5_2 | 3e-05 | 31.61% (174) | transmembrane transport protein MmpL5_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0980 | - | 1e-179 | 73.35% (454) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1873 | - | 1e-156 | 60.98% (469) | hypothetical protein Mflv_1873 |
| M. tuberculosis H37Rv | Rv0955 | - | 1e-179 | 73.35% (454) | integral membrane protein |
| M. leprae Br4923 | MLBr_00159 | - | 1e-174 | 71.88% (441) | hypothetical protein MLBr_00159 |
| M. abscessus ATCC 19977 | MAB_1062 | - | 1e-139 | 58.11% (444) | hypothetical protein MAB_1062 |
| M. avium 104 | MAV_1079 | - | 0.0 | 74.95% (463) | hypothetical protein MAV_1079 |
| M. smegmatis MC2 155 | MSMEG_5517 | - | 1e-164 | 66.52% (457) | hypothetical protein MSMEG_5517 |
| M. thermoresistible (build 8) | TH_2416 | - | 1e-05 | 25.48% (263) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4714 | - | 0.0 | 96.38% (469) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4858 | - | 1e-157 | 65.76% (441) | hypothetical protein Mvan_4858 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1873|M.gilvum_PYR-GCK ------------------MSTRPVGTRQARDLLRVAFGPSIVA--LVIIA
Mvan_4858|M.vanbaalenii_PYR-1 ------------------MSTRPVGTRQARDLLRVAFGPSLVA--LVIIA
MMAR_4544|M.marinum_M --------------MTRVEDSRAAGARQARDLVKVAFAPAVVA--LVIIA
MUL_4714|M.ulcerans_Agy99 -----------------MEDSRAAGARQARDLVKVAFAPAVVA--LVIIA
MLBr_00159|M.leprae_Br4923 -----------------MGDNRAAGVRQARDLVKVAFGPAVVA--LAIIA
MAV_1079|M.avium_104 -----------------MEDNRAAGARQARDLVRVAFAPAVVA--LVIIA
Mb0980|M.bovis_AF2122/97 -----------MNRVSASADDRAAGARPARDLVRVAFGPGVVA--LGIIA
Rv0955|M.tuberculosis_H37Rv -----------MNRVSASADDRAAGARPARDLVRVAFGPGVVA--LGIIA
MSMEG_5517|M.smegmatis_MC2_155 ------------------MNNGPVGTRQARELLRVAFGPSVVA--LVIIA
MAB_1062|M.abscessus_ATCC_1997 -----------------MNQPSRANPAQARALLTVAFGPSAVA--LVIIA
TH_2416|M.thermoresistible__bu VLEATFTAIFVPVLARAERDDPDGGTAFIRRLVTLATTLLLVTTLISVAA
. . * *: :* *: : : *
Mflv_1873|M.gilvum_PYR-GCK AIVLLQLLIAN-----SDMTGALG----------AIASIWLGVHQVPVSI
Mvan_4858|M.vanbaalenii_PYR-1 AVVLLQLLIAN-----SDMTGAFG----------AIASMWLGVHLVPVSI
MMAR_4544|M.marinum_M AVTLIQLVIAN-----SDMTGALG----------AIASMWLGVHQVPISI
MUL_4714|M.ulcerans_Agy99 AVTLIQLVIAN-----SDMTGALG----------AIASMWLGVHQVPISI
MLBr_00159|M.leprae_Br4923 AITLLQLLIAN-----SDMTGALG----------AIASMWLGVHQVPIAI
MAV_1079|M.avium_104 AVTLIQLLIAN-----SDMTGALG----------AIASMWLGVHQVPVSI
Mb0980|M.bovis_AF2122/97 AVTLLQLLIAN-----SDMTGAWG----------AIASMWLGVHLVPISI
Rv0955|M.tuberculosis_H37Rv AVTLLQLLIAN-----SDMTGAWG----------AIASMWLGVHLVPISI
MSMEG_5517|M.smegmatis_MC2_155 AVVLLQLVIAN-----SDMTGAFG----------AIASMWLGVHQVPVSI
MAB_1062|M.abscessus_ATCC_1997 AIVLVQLVIAN-----SDMTGTFG----------AVASMWLGTHLVPISI
TH_2416|M.thermoresistible__bu APALTRLMLGGDPQVNEPLTTAFAYLLLPQVLFYGLSSVFMAILNTRNVF
* .* :*::.. . :* : . .::*:::. . :
Mflv_1873|M.gilvum_PYR-GCK A----GTALGVMPLLPVLLMIYGTARTTAAATTST-SWFVTRWVVASALG
Mvan_4858|M.vanbaalenii_PYR-1 G----GSALGVMPLLPVLVMIYGTARTTAAATSS--SWFVTRWVVASALG
MMAR_4544|M.marinum_M G----GRELGVMPLFPALLMVWGTARTTALATSPYSSWLVVRWVIASALG
MUL_4714|M.ulcerans_Agy99 G----GRELGVMPLFPAMLMVWGTARTTALATSPYSSWLVVRWVIASALG
MLBr_00159|M.leprae_Br4923 G----GRELSIMPLLPVLLMVWATAHSTSQATSAYSSWLVIRWVVASALG
MAV_1079|M.avium_104 G----GRELGVLPLLPVLLMVWATARNTARATSPHSSWLVIRWVVASALG
Mb0980|M.bovis_AF2122/97 G----GRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALG
Rv0955|M.tuberculosis_H37Rv G----GRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALG
MSMEG_5517|M.smegmatis_MC2_155 G----GRELGVMPLLPVLAMVWGTAKTTAAATAPNSSWFVTRWVVASALG
MAB_1062|M.abscessus_ATCC_1997 G----GRVIEVLPLLPTAAMVWGVARTVASALAPTTSWYVIRWVIASALA
TH_2416|M.thermoresistible__bu GPPAWAPVVNNVVAIATLGLYLLVPGELSVDPVEMGNAKLLVLGIGTTLG
. . : : :.. : .. : . : :.::*.
Mflv_1873|M.gilvum_PYR-GCK GPILFTAICLAVIHDAASVLTELQTPDATRAFGGVFVVHLIGAVLG-VGS
Mvan_4858|M.vanbaalenii_PYR-1 GPVLIAAICLAVIHDAASVLTQLQTPDALHAFGYVFTVHAIGAVLG-VGS
MMAR_4544|M.marinum_M GPLLIAAICLAVIHDASSVITELQTPSALRAFVSVLAVHAIGAGLG-VWS
MUL_4714|M.ulcerans_Agy99 GPLLIAAICLAVIHDASSVITELQTPNALRAFVSVLAVHAIGAGLG-VWS
MLBr_00159|M.leprae_Br4923 GPLLIAAISLAVIHDASSVLTELQTPKALRAFTGVLVVHAIGAAIG-VNS
MAV_1079|M.avium_104 GPLLMTAVALAVIHDASSVITELQTPSALRAFLSVLVVHAIGAGIG-VWS
Mb0980|M.bovis_AF2122/97 GPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATG-VWS
Rv0955|M.tuberculosis_H37Rv GPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATG-VWS
MSMEG_5517|M.smegmatis_MC2_155 GPLLIAALLLAVIHDAASVITELQTPSALRAFGGVLAVHAIGALIG-VST
MAB_1062|M.abscessus_ATCC_1997 GPLLMTAISLAIIHDASTVLTQLQSPNALRAFGCVLGVHAVGAVIG-VVT
TH_2416|M.thermoresistible__bu VVAQCGVLVVAIRRERISLRPLWGIDDRLKRFGTMAAAMVLYVLISQIGL
.: :*: :: :: . . : * : . : . . :
Mflv_1873|M.gilvum_PYR-GCK RLGPRLLALSRLP-------AWIPDALRGAAAGVIALMGLSGAAVAGSLI
Mvan_4858|M.vanbaalenii_PYR-1 RVGRRLLSASPLP-------GWLPDAFRAAAAGVLALMGLSGAVVAGSLV
MMAR_4544|M.marinum_M RVGRRALAVSPLP-------NWLGDSLRAAAAGVLALLGLSGLVTAGSLV
MUL_4714|M.ulcerans_Agy99 RVGIRALAVSPLP-------NWLGDSLRAAAAGVLALLGLSGLVTAGSLV
MLBr_00159|M.leprae_Br4923 RVGRRVLTASRLP-------DWVGDSVHAATAGVLALLGLSGLVTAGSLV
MAV_1079|M.avium_104 QVGPRALAASSLP-------YWLGDSLRAATAGVLALLGLSGFVTAGSLV
Mb0980|M.bovis_AF2122/97 RVGRRALAATALP-------DWLHDSMRAAAAGVLALLGLSGVVTAGSLV
Rv0955|M.tuberculosis_H37Rv RVGRRALAATALP-------DWLHDSMRAAAAGVLALLGLSGVVTAGSLV
MSMEG_5517|M.smegmatis_MC2_155 KIGRRTLAASPLP-------KWLPDAVRAASAGVLALFALSGIVTAGSLV
MAB_1062|M.abscessus_ATCC_1997 RVGRRIALVLQLP-------SWPMDAARGAVAGVLALFGLSGAVTAGSLV
TH_2416|M.thermoresistible__bu VVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAA
:* : . * . ** .* : .:
Mflv_1873|M.gilvum_PYR-GCK VHWSTMHDLYSITESMFGQFSLTVLSVLYLPNIVIGAAAVAVG--SSAHI
Mvan_4858|M.vanbaalenii_PYR-1 VHWSTMHDLFSITDSMFGQLSLTVLSVLYLPNVMVGASAVAVG--SSAHI
MMAR_4544|M.marinum_M VHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVG--ASAHI
MUL_4714|M.ulcerans_Agy99 VHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVG--ASAHI
MLBr_00159|M.leprae_Br4923 VHWATMQEFYGITDSIFGQFSLTVLSVLYAPNVIVGTSAVAVG--SSAHL
MAV_1079|M.avium_104 VHWATMQELYGITDSIFGEFSLTVLSMLYAPNVIVGTAAVAVG--SSAHI
Mb0980|M.bovis_AF2122/97 VHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVG--SSAHI
Rv0955|M.tuberculosis_H37Rv VHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVG--SSAHI
MSMEG_5517|M.smegmatis_MC2_155 VHWGTMHDLFAITDTVFGQLSLTGLSVLYIPNVIVGTSAIAVG--SSAHI
MAB_1062|M.abscessus_ATCC_1997 VHWATMDQLYSVTNDFVGQLSLTLLAILYAPNVILGSCALAVG--SSAHV
TH_2416|M.thermoresistible__bu EDVPAVLRDFALAIRLTMVTLIPIVAVMTVGGPAIGTALFAYGNFGSVDA
. :: :.:: :. :::: . :*:. .* * .*..
Mflv_1873|M.gilvum_PYR-GCK G-LATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAVSAVALGQ
Mvan_4858|M.vanbaalenii_PYR-1 G-LATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAVSAVALGQ
MMAR_4544|M.marinum_M G-FATFSAFTVFGGDIPAVPILAAAPTPLLGPVWVALLIIGASSGVAVGQ
MUL_4714|M.ulcerans_Agy99 G-FATFSAFTVFGGDIPAVPILAAAPTPPLGPVWVALLIIGASSGVAVGQ
MLBr_00159|M.leprae_Br4923 G-FATFSSFTVFGGDIPALPVLAAAPTPPLAPVWVALLIVGAASGVAVGQ
MAV_1079|M.avium_104 G-FATFSSFTVFGGDIPALPVLAAVPRPPLGPVWVALLIIGASSGVAVGQ
Mb0980|M.bovis_AF2122/97 G-FATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQ
Rv0955|M.tuberculosis_H37Rv G-FATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQ
MSMEG_5517|M.smegmatis_MC2_155 G-LATFSSFTVFGGDIPAVPVLAAAPTPPLGPVWVALLIVGAASAVALGQ
MAB_1062|M.abscessus_ATCC_1997 G-TATFSAFAVFGGQLPAVPILAAVPTPPLGPAWVALMIIGAVSGVAVGQ
TH_2416|M.thermoresistible__bu GYLGMAITLSAFTLIPYALVLLQLRVFYARERPWTPIIVIVVITAVKIAA
* . :::.: *: :* *..:::: . :.* :.
Mflv_1873|M.gilvum_PYR-GCK QCARRPLPLVTALAKVVVAATVAAATMALLGFAGGGALGNFGQVGVDQST
Mvan_4858|M.vanbaalenii_PYR-1 QCARHPLPMPAALAKVLTAAAAAAGAMALLGHAGGGPLGNFGNVGVDQAT
MMAR_4544|M.marinum_M QCARRPLPPLPAMGKLLAAALVGALAMALLGYGGSGKLGNFGAVGVDEGA
MUL_4714|M.ulcerans_Agy99 QCARRPLPPLPAMGKLLAAALLGALAMALLGYGGSGKLGNFGAVGVDEGA
MLBr_00159|M.leprae_Br4923 QCTRHPLPLLAALAKLLVAAATGALMMALLGYAGSGRLGNFGDIDVDQGA
MAV_1079|M.avium_104 QCARRPLPPVAAMVKLLAASVAGALVMSLLAYAGSGQLGNFGHVGVDQGA
Mb0980|M.bovis_AF2122/97 QCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGA
Rv0955|M.tuberculosis_H37Rv QCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGA
MSMEG_5517|M.smegmatis_MC2_155 QCAARPLTPFAALAKLIVASLISAVTMALLGYAGSGRLGNFGHVGVDQST
MAB_1062|M.abscessus_ATCC_1997 QCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNFGRLGIDQGT
TH_2416|M.thermoresistible__bu SVAA---PHLTSDPDLVAGYLGLANGLGFAAGAVVGHLLLRAHLDPPGGR
. : . .: .::.. * :.. . * * . :. .
Mflv_1873|M.gilvum_PYR-GCK FAPAVFLWFAGIGGLTVVMSGGVTPRVRKPKPEPVRDADPD---------
Mvan_4858|M.vanbaalenii_PYR-1 FAPAVFLWFFGIGALTVAMSGGITPRVRKPKPVPEPAAVVDDAVI-----
MMAR_4544|M.marinum_M LLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPAPPVEAD---------
MUL_4714|M.ulcerans_Agy99 LLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPVPPAEAD---------
MLBr_00159|M.leprae_Br4923 LVVGVFFWFAVVGWVTVVVACGIKRFPRHLKPP--PALSS----------
MAV_1079|M.avium_104 LLVGVFFWFAVVGGATVVMSGGIRRPTRRLKPR--PAPAAP---------
Mb0980|M.bovis_AF2122/97 LVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPA--PPVELD---------
Rv0955|M.tuberculosis_H37Rv LVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPA--PPVELD---------
MSMEG_5517|M.smegmatis_MC2_155 FGPAVFLWFVGIGGLTVVMSGGIVRRVRVAPAAPPPAPEPEPEPVVPGEV
MAB_1062|M.abscessus_ATCC_1997 FGPGVFFWFLVIGLLTVFMLGGATRLPARTRRDPEPAPEPE---------
TH_2416|M.thermoresistible__bu LLEPAVVRTVLVTIAASLTAALIGQIADQLLGLEQLTANGG---------
: ... : :
Mflv_1873|M.gilvum_PYR-GCK ------AADPDAAEFDDQADPDDQAELED--TASGDETPEPPTEEFAADP
Mvan_4858|M.vanbaalenii_PYR-1 ---ETADAEPHTEEIALEAPPRDRPDPDPRIEPAGEPAPPVPDGPIDADL
MMAR_4544|M.marinum_M ------VDEPIHEPVDEPFVP--LFDQDAPLGDMTSREP-VAPGGDDADV
MUL_4714|M.ulcerans_Agy99 ------VDEPIHEPVDEPFVP--LFDQDAPLDDVTSREP-VAPGGDDADV
MLBr_00159|M.leprae_Br4923 --------EEH-------------ADASS-KDHEAYFGV-DLNVPFDLS-
MAV_1079|M.avium_104 ------VAEEHDSVFGEAVGP--VGDVAG-LDEIAAEGV-DEVAAEGVDE
Mb0980|M.bovis_AF2122/97 ------ADESS-------------PPVDM-FDGAASEQP-PASVAEDVP-
Rv0955|M.tuberculosis_H37Rv ------ADESS-------------PPVDM-FDGAASEQP-PASVAEDVP-
MSMEG_5517|M.smegmatis_MC2_155 LGEPAEADEPDDEPFGDEPYE--ETPEEPLVSWHADEPPEPAETDDDAGA
MAB_1062|M.abscessus_ATCC_1997 -------MDPE-------------PAPAPEPDPEPAPEPEPQREPEPESE
TH_2416|M.thermoresistible__bu ------GAGSLLRLLVLGLIMAPVIAAFLWFARVPEAEAAVAAVRRRFGK
Mflv_1873|M.gilvum_PYR-GCK PP-----TDRDPEPVPHDAVADTPPVDD-----LDPEE--HFVVDDDMGR
Mvan_4858|M.vanbaalenii_PYR-1 DPEDHFVVDEQTSPFVEDEENGHFVEDEENGPFVEDEENGHFVEDEENGL
MMAR_4544|M.marinum_M PP-----AAPDEADWSDGPDRPDGPDRQDGPD--ASHPPEHLT-------
MUL_4714|M.ulcerans_Agy99 PP-----AAPDEVDWSDGPD------RQDGPD--TSHPPEHLT-------
MLBr_00159|M.leprae_Br4923 ----------GEDEIPKAEPGEAA-D------------------------
MAV_1079|M.avium_104 SP-----GDAGEREGDEGDPGERG-SGDAGAA--GERRPGE---------
Mb0980|M.bovis_AF2122/97 ---------PSHDDIANGLKAPTA-DDEALPL--SDEPPPRAD-------
Rv0955|M.tuberculosis_H37Rv ---------PSHDDIANGLKAPTA-DDEALPL--SDEPPPRAD-------
MSMEG_5517|M.smegmatis_MC2_155 PV-----APRSPRDLLDEDPEDHFFVDEFGDEEVSGDKPRNAED------
MAB_1062|M.abscessus_ATCC_1997 PE-------ADTDEGPEIDPSDPPESAK----------------------
TH_2416|M.thermoresistible__bu TP------ASGPAPVTAGDRRCTGADSQPGGDYRGRIPARSAFPVP----
Mflv_1873|M.gilvum_PYR-GCK -----NGGPPRDH---
Mvan_4858|M.vanbaalenii_PYR-1 SVVDDDSGGKREQGDH
MMAR_4544|M.marinum_M ----------------
MUL_4714|M.ulcerans_Agy99 ----------------
MLBr_00159|M.leprae_Br4923 ----------------
MAV_1079|M.avium_104 ----------------
Mb0980|M.bovis_AF2122/97 ----------------
Rv0955|M.tuberculosis_H37Rv ----------------
MSMEG_5517|M.smegmatis_MC2_155 ----------------
MAB_1062|M.abscessus_ATCC_1997 ----------------
TH_2416|M.thermoresistible__bu ----------------