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VNQPSRANPAQARALLTVAFGPSAVALVIIAAIVLVQLVIANSDMTGTFGAVASMWLGTHLVPISIGGRV IEVLPLLPTAAMVWGVARTVASALAPTTSWYVIRWVIASALAGPLLMTAISLAIIHDASTVLTQLQSPNA LRAFGCVLGVHAVGAVIGVVTRVGRRIALVLQLPSWPMDAARGAVAGVLALFGLSGAVTAGSLVVHWATM DQLYSVTNDFVGQLSLTLLAILYAPNVILGSCALAVGSSAHVGTATFSAFAVFGGQLPAVPILAAVPTPP LGPAWVALMIIGAVSGVAVGQQCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNFGRLGIDQG TFGPGVFFWFLVIGLLTVFMLGGATRLPARTRRDPEPAPEPEMDPEPAPAPEPDPEPAPEPEPQREPEPE SEPEADTDEGPEIDPSDPPESAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1062 | - | - | 100% (443) | hypothetical protein MAB_1062 |
| M. abscessus ATCC 19977 | MAB_0309 | - | 5e-11 | 50.72% (69) | DNA polymerase III, subunit gamma/tau |
| M. abscessus ATCC 19977 | MAB_4012c | - | 2e-07 | 45.28% (53) | hypothetical protein MAB_4012c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0980 | - | 1e-136 | 56.33% (442) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1873 | - | 1e-140 | 59.31% (435) | hypothetical protein Mflv_1873 |
| M. tuberculosis H37Rv | Rv0955 | - | 1e-136 | 56.33% (442) | integral membrane protein |
| M. leprae Br4923 | MLBr_00159 | - | 1e-133 | 59.54% (388) | hypothetical protein MLBr_00159 |
| M. marinum M | MMAR_4544 | - | 1e-139 | 55.67% (467) | integral membrane protein |
| M. avium 104 | MAV_1079 | - | 1e-134 | 57.34% (443) | hypothetical protein MAV_1079 |
| M. smegmatis MC2 155 | MSMEG_5517 | - | 1e-148 | 59.64% (446) | hypothetical protein MSMEG_5517 |
| M. thermoresistible (build 8) | TH_2833 | - | 3e-11 | 45.16% (62) | PUTATIVE 2-oxoglutarate dehydrogenase, E2 component, |
| M. ulcerans Agy99 | MUL_4714 | - | 1e-141 | 57.17% (460) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4858 | - | 1e-146 | 60.09% (441) | hypothetical protein Mvan_4858 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4544|M.marinum_M ---MTRVEDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSD
MUL_4714|M.ulcerans_Agy99 ------MEDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSD
MLBr_00159|M.leprae_Br4923 ------MGDNRAAGVRQARDLVKVAFGPAVVALAIIAAITLLQLLIANSD
MAV_1079|M.avium_104 ------MEDNRAAGARQARDLVRVAFAPAVVALVIIAAVTLIQLLIANSD
Mb0980|M.bovis_AF2122/97 MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSD
Rv0955|M.tuberculosis_H37Rv MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSD
MSMEG_5517|M.smegmatis_MC2_155 -------MNNGPVGTRQARELLRVAFGPSVVALVIIAAVVLLQLVIANSD
Mflv_1873|M.gilvum_PYR-GCK -------MSTRPVGTRQARDLLRVAFGPSIVALVIIAAIVLLQLLIANSD
Mvan_4858|M.vanbaalenii_PYR-1 -------MSTRPVGTRQARDLLRVAFGPSLVALVIIAAVVLLQLLIANSD
MAB_1062|M.abscessus_ATCC_1997 ------MNQPSRANPAQARALLTVAFGPSAVALVIIAAIVLVQLVIANSD
TH_2833|M.thermoresistible__bu -------VLMPELGESVTEGTVTRWLKKVGDTVEVDEPLLEVSTDKVDTE
. :. : : :: : .: :. .:::
MMAR_4544|M.marinum_M MTGALGAIASMWLGVHQVPISIGGRELGVMPLFPALLMVWGTARTTALAT
MUL_4714|M.ulcerans_Agy99 MTGALGAIASMWLGVHQVPISIGGRELGVMPLFPAMLMVWGTARTTALAT
MLBr_00159|M.leprae_Br4923 MTGALGAIASMWLGVHQVPIAIGGRELSIMPLLPVLLMVWATAHSTSQAT
MAV_1079|M.avium_104 MTGALGAIASMWLGVHQVPVSIGGRELGVLPLLPVLLMVWATARNTARAT
Mb0980|M.bovis_AF2122/97 MTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARAT
Rv0955|M.tuberculosis_H37Rv MTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARAT
MSMEG_5517|M.smegmatis_MC2_155 MTGAFGAIASMWLGVHQVPVSIGGRELGVMPLLPVLAMVWGTAKTTAAAT
Mflv_1873|M.gilvum_PYR-GCK MTGALGAIASIWLGVHQVPVSIAGTALGVMPLLPVLLMIYGTARTTAAAT
Mvan_4858|M.vanbaalenii_PYR-1 MTGAFGAIASMWLGVHLVPVSIGGSALGVMPLLPVLVMIYGTARTTAAAT
MAB_1062|M.abscessus_ATCC_1997 MTGTFGAVASMWLGTHLVPISIGGRVIEVLPLLPTAAMVWGVARTVASAL
TH_2833|M.thermoresistible__bu IPSPVAGTLVSITAEEDATVEVGGELAVIGEAGAQAGAQPEPEPEPRPEP
:... .. . . ..: :.* : .
MMAR_4544|M.marinum_M SPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTPSALRAF
MUL_4714|M.ulcerans_Agy99 SPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTPNALRAF
MLBr_00159|M.leprae_Br4923 SAYSSWLVIRWVVASALGGPLLIAAISLAVIHDASSVLTELQTPKALRAF
MAV_1079|M.avium_104 SPHSSWLVIRWVVASALGGPLLMTAVALAVIHDASSVITELQTPSALRAF
Mb0980|M.bovis_AF2122/97 SPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAF
Rv0955|M.tuberculosis_H37Rv SPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAF
MSMEG_5517|M.smegmatis_MC2_155 APNSSWFVTRWVVASALGGPLLIAALLLAVIHDAASVITELQTPSALRAF
Mflv_1873|M.gilvum_PYR-GCK TST-SWFVTRWVVASALGGPILFTAICLAVIHDAASVLTELQTPDATRAF
Mvan_4858|M.vanbaalenii_PYR-1 SS--SWFVTRWVVASALGGPVLIAAICLAVIHDAASVLTQLQTPDALHAF
MAB_1062|M.abscessus_ATCC_1997 APTTSWYVIRWVIASALAGPLLMTAISLAIIHDASTVLTQLQSPNALRAF
TH_2833|M.thermoresistible__bu EPAPQPEPEPEQKAAPQPQPESRPEPQPQPARQAPQRESGPYVTPLVRKL
. . *:. * . ::*. : . : :
MMAR_4544|M.marinum_M VSVLAVHAIGAG-LGVWSRVGRR-ALAVSPLPNWLGDSLRAAAAGVLALL
MUL_4714|M.ulcerans_Agy99 VSVLAVHAIGAG-LGVWSRVGIR-ALAVSPLPNWLGDSLRAAAAGVLALL
MLBr_00159|M.leprae_Br4923 TGVLVVHAIGAA-IGVNSRVGRR-VLTASRLPDWVGDSVHAATAGVLALL
MAV_1079|M.avium_104 LSVLVVHAIGAG-IGVWSQVGPR-ALAASSLPYWLGDSLRAATAGVLALL
Mb0980|M.bovis_AF2122/97 TSVLVVHSVGAA-TGVWSRVGRR-ALAATALPDWLHDSMRAAAAGVLALL
Rv0955|M.tuberculosis_H37Rv TSVLVVHSVGAA-TGVWSRVGRR-ALAATALPDWLHDSMRAAAAGVLALL
MSMEG_5517|M.smegmatis_MC2_155 GGVLAVHAIGAL-IGVSTKIGRR-TLAASPLPKWLPDAVRAASAGVLALF
Mflv_1873|M.gilvum_PYR-GCK GGVFVVHLIGAV-LGVGSRLGPR-LLALSRLPAWIPDALRGAAAGVIALM
Mvan_4858|M.vanbaalenii_PYR-1 GYVFTVHAIGAV-LGVGSRVGRR-LLSASPLPGWLPDAFRAAAAGVLALM
MAB_1062|M.abscessus_ATCC_1997 GCVLGVHAVGAV-IGVVTRVGRR-IALVLQLPSWPMDAARGAVAGVLALF
TH_2833|M.thermoresistible__bu AAEHGVDLSTVKGTGVGGRIRKQDVLAAAEAAKKAAEAPAAEPAETAKPA
*. . ** :: : . :: . * .
MMAR_4544|M.marinum_M GLSGLVTAGSLVVHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAA
MUL_4714|M.ulcerans_Agy99 GLSGLVTAGSLVVHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAA
MLBr_00159|M.leprae_Br4923 GLSGLVTAGSLVVHWATMQEFYGITDSIFGQFSLTVLSVLYAPNVIVGTS
MAV_1079|M.avium_104 GLSGFVTAGSLVVHWATMQELYGITDSIFGEFSLTVLSMLYAPNVIVGTA
Mb0980|M.bovis_AF2122/97 GLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTS
Rv0955|M.tuberculosis_H37Rv GLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTS
MSMEG_5517|M.smegmatis_MC2_155 ALSGIVTAGSLVVHWGTMHDLFAITDTVFGQLSLTGLSVLYIPNVIVGTS
Mflv_1873|M.gilvum_PYR-GCK GLSGAAVAGSLIVHWSTMHDLYSITESMFGQFSLTVLSVLYLPNIVIGAA
Mvan_4858|M.vanbaalenii_PYR-1 GLSGAVVAGSLVVHWSTMHDLFSITDSMFGQLSLTVLSVLYLPNVMVGAS
MAB_1062|M.abscessus_ATCC_1997 GLSGAVTAGSLVVHWATMDQLYSVTNDFVGQLSLTLLAILYAPNVILGSC
TH_2833|M.thermoresistible__bu AAAASAAPESPLAHLRGTTKKASRIRQITAQRTRESLQTTAQLTQVHEVD
. :. ... * :.* . . .: : * . :
MMAR_4544|M.marinum_M AIAVGASAHIGFATFSAFTVFGGDIPAVPILAAAPTPLLGPVWVALLIIG
MUL_4714|M.ulcerans_Agy99 AIAVGASAHIGFATFSAFTVFGGDIPAVPILAAAPTPPLGPVWVALLIIG
MLBr_00159|M.leprae_Br4923 AVAVGSSAHLGFATFSSFTVFGGDIPALPVLAAAPTPPLAPVWVALLIVG
MAV_1079|M.avium_104 AVAVGSSAHIGFATFSSFTVFGGDIPALPVLAAVPRPPLGPVWVALLIIG
Mb0980|M.bovis_AF2122/97 AIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVG
Rv0955|M.tuberculosis_H37Rv AIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVG
MSMEG_5517|M.smegmatis_MC2_155 AIAVGSSAHIGLATFSSFTVFGGDIPAVPVLAAAPTPPLGPVWVALLIVG
Mflv_1873|M.gilvum_PYR-GCK AVAVGSSAHIGLATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIA
Mvan_4858|M.vanbaalenii_PYR-1 AVAVGSSAHIGLATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIA
MAB_1062|M.abscessus_ATCC_1997 ALAVGSSAHVGTATFSAFAVFGGQLPAVPILAAVPTPPLGPAWVALMIIG
TH_2833|M.thermoresistible__bu MTKIVALRARAKAEFR--EREGVNLTYLPFIARAVIDALK----------
: : . * * * ::. :*.:* . *
MMAR_4544|M.marinum_M ASSGVAVGQQCARRPLPPLPAMGKLLAAALVGALAMALLGYGGSGKLGNF
MUL_4714|M.ulcerans_Agy99 ASSGVAVGQQCARRPLPPLPAMGKLLAAALLGALAMALLGYGGSGKLGNF
MLBr_00159|M.leprae_Br4923 AASGVAVGQQCTRHPLPLLAALAKLLVAAATGALMMALLGYAGSGRLGNF
MAV_1079|M.avium_104 ASSGVAVGQQCARRPLPPVAAMVKLLAASVAGALVMSLLAYAGSGQLGNF
Mb0980|M.bovis_AF2122/97 ASSGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNF
Rv0955|M.tuberculosis_H37Rv ASSGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNF
MSMEG_5517|M.smegmatis_MC2_155 AASAVALGQQCAARPLTPFAALAKLIVASLISAVTMALLGYAGSGRLGNF
Mflv_1873|M.gilvum_PYR-GCK AVSAVALGQQCARRPLPLVTALAKVVVAATVAAATMALLGFAGGGALGNF
Mvan_4858|M.vanbaalenii_PYR-1 AVSAVALGQQCARHPLPMPAALAKVLTAAAAAAGAMALLGHAGGGPLGNF
MAB_1062|M.abscessus_ATCC_1997 AVSGVAVGQQCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNF
TH_2833|M.thermoresistible__bu AHPNVNASYNEETKEITYYDAEHLGIAVDTEKGLLSPVIHNAGDLSLGGL
* . * . : : :. * :.. . .:: .. **.:
MMAR_4544|M.marinum_M GAVGVDEGALLVGVFFWFAVVG--GATLVMAGGIRRRPRRPKPRPAPPVE
MUL_4714|M.ulcerans_Agy99 GAVGVDEGALLVGVFFWFAVVG--GATLVMAGGIRRRPRRPKPRPVPPAE
MLBr_00159|M.leprae_Br4923 GDIDVDQGALVVGVFFWFAVVG--WVTVVVACGIKRFPRHLKPPPALSS-
MAV_1079|M.avium_104 GHVGVDQGALLVGVFFWFAVVG--GATVVMSGGIRRPTRRLKPRPAPAAP
Mb0980|M.bovis_AF2122/97 GDVGVDEGALVLGVLFWFTFVG--WVTVVIAGGISRRPKRLRPAPPVELD
Rv0955|M.tuberculosis_H37Rv GDVGVDEGALVLGVLFWFTFVG--WVTVVIAGGISRRPKRLRPAPPVELD
MSMEG_5517|M.smegmatis_MC2_155 GHVGVDQSTFGPAVFLWFVGIG--GLTVVMSGGIVRRVRVAPAAPPPAPE
Mflv_1873|M.gilvum_PYR-GCK GQVGVDQSTFAPAVFLWFAGIG--GLTVVMSGGVTPRVRKPKPEPVRDAD
Mvan_4858|M.vanbaalenii_PYR-1 GNVGVDQATFAPAVFLWFFGIG--ALTVAMSGGITPRVRKPKPVPEPAAV
MAB_1062|M.abscessus_ATCC_1997 GRLGIDQGTFGPGVFFWFLVIG--LLTVFMLGGATRLPARTRRDPEPAPE
TH_2833|M.thermoresistible__bu ARAIADIAARARSGDLKPDELSGGTFTITNIGSQGALFDTPILVPPQAAM
. * .: . : :. *: . *
MMAR_4544|M.marinum_M ADVDEPIH-----------EPVDEPFVPLFDQDAPLGDMTSREP-VAPGG
MUL_4714|M.ulcerans_Agy99 ADVDEPIH-----------EPVDEPFVPLFDQDAPLDDVTSREP-VAPGG
MLBr_00159|M.leprae_Br4923 ----------------------EEH-----------ADASSKDH-EAYFG
MAV_1079|M.avium_104 V--------------------AEEHDSVFGEAVGPVGDVAGLDE-IAAEG
Mb0980|M.bovis_AF2122/97 AD-------------------ESSPPVDMFDGAASEQPPASVAE-DVPPS
Rv0955|M.tuberculosis_H37Rv AD-------------------ESSPPVDMFDGAASEQPPASVAE-DVPPS
MSMEG_5517|M.smegmatis_MC2_155 PEPEPVVPGEVLGEPAEADEPDDEPFGDEPYEETPEEPLVSWHA-DEPPE
Mflv_1873|M.gilvum_PYR-GCK PD-------------------AADPDAAEFDDQADPDDQAELED--TASG
Mvan_4858|M.vanbaalenii_PYR-1 VDDAVIET------------ADAEPHTEEIALEAPPRDRPDPDPRIEPAG
MAB_1062|M.abscessus_ATCC_1997 PE---------------------------MDPEPAPAPEPDPEP-APEPE
TH_2833|M.thermoresistible__bu LGTG-----------------AIVKRPRVIEDEFGNESIGIRSVCYLPLT
MMAR_4544|M.marinum_M DDADVPPAAPDEADWSDGPDRPDGPDRQDGPDASHPPEHLT---------
MUL_4714|M.ulcerans_Agy99 DDADVPPAAPDEVDWSDGPD------RQDGPDTSHPPEHLT---------
MLBr_00159|M.leprae_Br4923 ----VDLNVPFDLS------------GEDEIPKAEPGEAAD---------
MAV_1079|M.avium_104 ----VDEVAAEGVDESPGDA------GEREGDEGDPGERGSGDAGAAGER
Mb0980|M.bovis_AF2122/97 HDDIANGLKAPTADD------------EALPLSDEPPPRAD---------
Rv0955|M.tuberculosis_H37Rv HDDIANGLKAPTADD------------EALPLSDEPPPRAD---------
MSMEG_5517|M.smegmatis_MC2_155 PAETDDDAGAPVAPRSPRDLLD-----EDPEDHFFVDEFGDEEVSGDKPR
Mflv_1873|M.gilvum_PYR-GCK DETPEPPTEEFAADPPP-----TDRDPEPVPHDAVADTPPVDD-----LD
Mvan_4858|M.vanbaalenii_PYR-1 EPAPPVPDGPIDADLDPEDHFVVDEQTSPFVEDEENGHFVEDEENGPFVE
MAB_1062|M.abscessus_ATCC_1997 PQREPEPESEPEADTDE----------GPEIDPSDPPESAK---------
TH_2833|M.thermoresistible__bu YDHRLIDGADAGRFLTT--------IKKRLEEGAFEAELGL---------
MMAR_4544|M.marinum_M -------------------------------
MUL_4714|M.ulcerans_Agy99 -------------------------------
MLBr_00159|M.leprae_Br4923 -------------------------------
MAV_1079|M.avium_104 RPGE---------------------------
Mb0980|M.bovis_AF2122/97 -------------------------------
Rv0955|M.tuberculosis_H37Rv -------------------------------
MSMEG_5517|M.smegmatis_MC2_155 NAED---------------------------
Mflv_1873|M.gilvum_PYR-GCK PEE--HFVVDDDMGR-----NGGPPRDH---
Mvan_4858|M.vanbaalenii_PYR-1 DEENGHFVEDEENGLSVVDDDSGGKREQGDH
MAB_1062|M.abscessus_ATCC_1997 -------------------------------
TH_2833|M.thermoresistible__bu -------------------------------