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EDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSDMTGALGAIASMWLGVHQVPISIGGREL GVMPLFPAMLMVWGTARTTALATSPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTPNAL RAFVSVLAVHAIGAGLGVWSRVGIRALAVSPLPNWLGDSLRAAAAGVLALLGLSGLVTAGSLVVHWATMQ ELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVGASAHIGFATFSAFTVFGGDIPAVPILAAAPTPPL GPVWVALLIIGASSGVAVGQQCARRPLPPLPAMGKLLAAALLGALAMALLGYGGSGKLGNFGAVGVDEGA LLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPVPPAEADVDEPIHEPVDEPFVPLFDQDAPLDDVTSR EPVAPGGDDADVPPAAPDEVDWSDGPDRQDGPDTSHPPEHLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4714 | - | - | 100% (463) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0980 | - | 1e-178 | 71.90% (459) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1873 | - | 1e-158 | 61.42% (464) | hypothetical protein Mflv_1873 |
| M. tuberculosis H37Rv | Rv0955 | - | 1e-178 | 71.90% (459) | integral membrane protein |
| M. leprae Br4923 | MLBr_00159 | - | 1e-174 | 76.56% (401) | hypothetical protein MLBr_00159 |
| M. abscessus ATCC 19977 | MAB_1062 | - | 1e-141 | 57.17% (460) | hypothetical protein MAB_1062 |
| M. marinum M | MMAR_4544 | - | 0.0 | 96.38% (469) | integral membrane protein |
| M. avium 104 | MAV_1079 | - | 0.0 | 75.00% (460) | hypothetical protein MAV_1079 |
| M. smegmatis MC2 155 | MSMEG_5517 | - | 1e-164 | 66.96% (448) | hypothetical protein MSMEG_5517 |
| M. thermoresistible (build 8) | TH_2416 | - | 6e-05 | 24.61% (256) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_4858 | - | 1e-156 | 65.31% (441) | hypothetical protein Mvan_4858 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1873|M.gilvum_PYR-GCK ------------------MSTRPVGTRQARDLLRVAFGPSIVA--LVIIA
Mvan_4858|M.vanbaalenii_PYR-1 ------------------MSTRPVGTRQARDLLRVAFGPSLVA--LVIIA
MUL_4714|M.ulcerans_Agy99 -----------------MEDSRAAGARQARDLVKVAFAPAVVA--LVIIA
MMAR_4544|M.marinum_M --------------MTRVEDSRAAGARQARDLVKVAFAPAVVA--LVIIA
MLBr_00159|M.leprae_Br4923 -----------------MGDNRAAGVRQARDLVKVAFGPAVVA--LAIIA
MAV_1079|M.avium_104 -----------------MEDNRAAGARQARDLVRVAFAPAVVA--LVIIA
Mb0980|M.bovis_AF2122/97 -----------MNRVSASADDRAAGARPARDLVRVAFGPGVVA--LGIIA
Rv0955|M.tuberculosis_H37Rv -----------MNRVSASADDRAAGARPARDLVRVAFGPGVVA--LGIIA
MSMEG_5517|M.smegmatis_MC2_155 ------------------MNNGPVGTRQARELLRVAFGPSVVA--LVIIA
MAB_1062|M.abscessus_ATCC_1997 -----------------MNQPSRANPAQARALLTVAFGPSAVA--LVIIA
TH_2416|M.thermoresistible__bu VLEATFTAIFVPVLARAERDDPDGGTAFIRRLVTLATTLLLVTTLISVAA
. . * *: :* *: : : *
Mflv_1873|M.gilvum_PYR-GCK AIVLLQLLIAN-----SDMTGALG----------AIASIWLGVHQVPVSI
Mvan_4858|M.vanbaalenii_PYR-1 AVVLLQLLIAN-----SDMTGAFG----------AIASMWLGVHLVPVSI
MUL_4714|M.ulcerans_Agy99 AVTLIQLVIAN-----SDMTGALG----------AIASMWLGVHQVPISI
MMAR_4544|M.marinum_M AVTLIQLVIAN-----SDMTGALG----------AIASMWLGVHQVPISI
MLBr_00159|M.leprae_Br4923 AITLLQLLIAN-----SDMTGALG----------AIASMWLGVHQVPIAI
MAV_1079|M.avium_104 AVTLIQLLIAN-----SDMTGALG----------AIASMWLGVHQVPVSI
Mb0980|M.bovis_AF2122/97 AVTLLQLLIAN-----SDMTGAWG----------AIASMWLGVHLVPISI
Rv0955|M.tuberculosis_H37Rv AVTLLQLLIAN-----SDMTGAWG----------AIASMWLGVHLVPISI
MSMEG_5517|M.smegmatis_MC2_155 AVVLLQLVIAN-----SDMTGAFG----------AIASMWLGVHQVPVSI
MAB_1062|M.abscessus_ATCC_1997 AIVLVQLVIAN-----SDMTGTFG----------AVASMWLGTHLVPISI
TH_2416|M.thermoresistible__bu APALTRLMLGGDPQVNEPLTTAFAYLLLPQVLFYGLSSVFMAILNTRNVF
* .* :*::.. . :* : . .::*:::. . :
Mflv_1873|M.gilvum_PYR-GCK A----GTALGVMPLLPVLLMIYGTARTTAAATTST-SWFVTRWVVASALG
Mvan_4858|M.vanbaalenii_PYR-1 G----GSALGVMPLLPVLVMIYGTARTTAAATSS--SWFVTRWVVASALG
MUL_4714|M.ulcerans_Agy99 G----GRELGVMPLFPAMLMVWGTARTTALATSPYSSWLVVRWVIASALG
MMAR_4544|M.marinum_M G----GRELGVMPLFPALLMVWGTARTTALATSPYSSWLVVRWVIASALG
MLBr_00159|M.leprae_Br4923 G----GRELSIMPLLPVLLMVWATAHSTSQATSAYSSWLVIRWVVASALG
MAV_1079|M.avium_104 G----GRELGVLPLLPVLLMVWATARNTARATSPHSSWLVIRWVVASALG
Mb0980|M.bovis_AF2122/97 G----GRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALG
Rv0955|M.tuberculosis_H37Rv G----GRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALG
MSMEG_5517|M.smegmatis_MC2_155 G----GRELGVMPLLPVLAMVWGTAKTTAAATAPNSSWFVTRWVVASALG
MAB_1062|M.abscessus_ATCC_1997 G----GRVIEVLPLLPTAAMVWGVARTVASALAPTTSWYVIRWVIASALA
TH_2416|M.thermoresistible__bu GPPAWAPVVNNVVAIATLGLYLLVPGELSVDPVEMGNAKLLVLGIGTTLG
. . : : :.. : .. : . : :.::*.
Mflv_1873|M.gilvum_PYR-GCK GPILFTAICLAVIHDAASVLTELQTPDATRAFGGVFVVHLIGAVLG-VGS
Mvan_4858|M.vanbaalenii_PYR-1 GPVLIAAICLAVIHDAASVLTQLQTPDALHAFGYVFTVHAIGAVLG-VGS
MUL_4714|M.ulcerans_Agy99 GPLLIAAICLAVIHDASSVITELQTPNALRAFVSVLAVHAIGAGLG-VWS
MMAR_4544|M.marinum_M GPLLIAAICLAVIHDASSVITELQTPSALRAFVSVLAVHAIGAGLG-VWS
MLBr_00159|M.leprae_Br4923 GPLLIAAISLAVIHDASSVLTELQTPKALRAFTGVLVVHAIGAAIG-VNS
MAV_1079|M.avium_104 GPLLMTAVALAVIHDASSVITELQTPSALRAFLSVLVVHAIGAGIG-VWS
Mb0980|M.bovis_AF2122/97 GPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATG-VWS
Rv0955|M.tuberculosis_H37Rv GPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATG-VWS
MSMEG_5517|M.smegmatis_MC2_155 GPLLIAALLLAVIHDAASVITELQTPSALRAFGGVLAVHAIGALIG-VST
MAB_1062|M.abscessus_ATCC_1997 GPLLMTAISLAIIHDASTVLTQLQSPNALRAFGCVLGVHAVGAVIG-VVT
TH_2416|M.thermoresistible__bu VVAQCGVLVVAIRRERISLRPLWGIDDRLKRFGTMAAAMVLYVLISQIGL
.: :*: :: :: . . : * : . : . . :
Mflv_1873|M.gilvum_PYR-GCK RLGPRLLALSRLP-------AWIPDALRGAAAGVIALMGLSGAAVAGSLI
Mvan_4858|M.vanbaalenii_PYR-1 RVGRRLLSASPLP-------GWLPDAFRAAAAGVLALMGLSGAVVAGSLV
MUL_4714|M.ulcerans_Agy99 RVGIRALAVSPLP-------NWLGDSLRAAAAGVLALLGLSGLVTAGSLV
MMAR_4544|M.marinum_M RVGRRALAVSPLP-------NWLGDSLRAAAAGVLALLGLSGLVTAGSLV
MLBr_00159|M.leprae_Br4923 RVGRRVLTASRLP-------DWVGDSVHAATAGVLALLGLSGLVTAGSLV
MAV_1079|M.avium_104 QVGPRALAASSLP-------YWLGDSLRAATAGVLALLGLSGFVTAGSLV
Mb0980|M.bovis_AF2122/97 RVGRRALAATALP-------DWLHDSMRAAAAGVLALLGLSGVVTAGSLV
Rv0955|M.tuberculosis_H37Rv RVGRRALAATALP-------DWLHDSMRAAAAGVLALLGLSGVVTAGSLV
MSMEG_5517|M.smegmatis_MC2_155 KIGRRTLAASPLP-------KWLPDAVRAASAGVLALFALSGIVTAGSLV
MAB_1062|M.abscessus_ATCC_1997 RVGRRIALVLQLP-------SWPMDAARGAVAGVLALFGLSGAVTAGSLV
TH_2416|M.thermoresistible__bu VVGNQIASGAAASGPAIYNYTWLVLMLPFGMIGVTVLTVVMPRLSRNAAA
:* : . * . ** .* : .:
Mflv_1873|M.gilvum_PYR-GCK VHWSTMHDLYSITESMFGQFSLTVLSVLYLPNIVIGAAAVAVG--SSAHI
Mvan_4858|M.vanbaalenii_PYR-1 VHWSTMHDLFSITDSMFGQLSLTVLSVLYLPNVMVGASAVAVG--SSAHI
MUL_4714|M.ulcerans_Agy99 VHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVG--ASAHI
MMAR_4544|M.marinum_M VHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAIAVG--ASAHI
MLBr_00159|M.leprae_Br4923 VHWATMQEFYGITDSIFGQFSLTVLSVLYAPNVIVGTSAVAVG--SSAHL
MAV_1079|M.avium_104 VHWATMQELYGITDSIFGEFSLTVLSMLYAPNVIVGTAAVAVG--SSAHI
Mb0980|M.bovis_AF2122/97 VHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVG--SSAHI
Rv0955|M.tuberculosis_H37Rv VHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVG--SSAHI
MSMEG_5517|M.smegmatis_MC2_155 VHWGTMHDLFAITDTVFGQLSLTGLSVLYIPNVIVGTSAIAVG--SSAHI
MAB_1062|M.abscessus_ATCC_1997 VHWATMDQLYSVTNDFVGQLSLTLLAILYAPNVILGSCALAVG--SSAHV
TH_2416|M.thermoresistible__bu EDVPAVLRDFALAIRLTMVTLIPIVAVMTVGGPAIGTALFAYGNFGSVDA
. :: :.:: :. :::: . :*:. .* * .*..
Mflv_1873|M.gilvum_PYR-GCK G-LATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAVSAVALGQ
Mvan_4858|M.vanbaalenii_PYR-1 G-LATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAVSAVALGQ
MUL_4714|M.ulcerans_Agy99 G-FATFSAFTVFGGDIPAVPILAAAPTPPLGPVWVALLIIGASSGVAVGQ
MMAR_4544|M.marinum_M G-FATFSAFTVFGGDIPAVPILAAAPTPLLGPVWVALLIIGASSGVAVGQ
MLBr_00159|M.leprae_Br4923 G-FATFSSFTVFGGDIPALPVLAAAPTPPLAPVWVALLIVGAASGVAVGQ
MAV_1079|M.avium_104 G-FATFSSFTVFGGDIPALPVLAAVPRPPLGPVWVALLIIGASSGVAVGQ
Mb0980|M.bovis_AF2122/97 G-FATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQ
Rv0955|M.tuberculosis_H37Rv G-FATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQ
MSMEG_5517|M.smegmatis_MC2_155 G-LATFSSFTVFGGDIPAVPVLAAAPTPPLGPVWVALLIVGAASAVALGQ
MAB_1062|M.abscessus_ATCC_1997 G-TATFSAFAVFGGQLPAVPILAAVPTPPLGPAWVALMIIGAVSGVAVGQ
TH_2416|M.thermoresistible__bu GYLGMAITLSAFTLIPYALVLLQLRVFYARERPWTPIIVIVVITAVKIAA
* . :::.: *: :* *..:::: . :.* :.
Mflv_1873|M.gilvum_PYR-GCK QCARRPLPLVTALAKVVVAATVAAATMALLGFAGGGALGNFGQVGVDQST
Mvan_4858|M.vanbaalenii_PYR-1 QCARHPLPMPAALAKVLTAAAAAAGAMALLGHAGGGPLGNFGNVGVDQAT
MUL_4714|M.ulcerans_Agy99 QCARRPLPPLPAMGKLLAAALLGALAMALLGYGGSGKLGNFGAVGVDEGA
MMAR_4544|M.marinum_M QCARRPLPPLPAMGKLLAAALVGALAMALLGYGGSGKLGNFGAVGVDEGA
MLBr_00159|M.leprae_Br4923 QCTRHPLPLLAALAKLLVAAATGALMMALLGYAGSGRLGNFGDIDVDQGA
MAV_1079|M.avium_104 QCARRPLPPVAAMVKLLAASVAGALVMSLLAYAGSGQLGNFGHVGVDQGA
Mb0980|M.bovis_AF2122/97 QCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGA
Rv0955|M.tuberculosis_H37Rv QCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGA
MSMEG_5517|M.smegmatis_MC2_155 QCAARPLTPFAALAKLIVASLISAVTMALLGYAGSGRLGNFGHVGVDQST
MAB_1062|M.abscessus_ATCC_1997 QCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNFGRLGIDQGT
TH_2416|M.thermoresistible__bu SVAA---PHLTSDPDLVAGYLGLANGLGFAAGAVVGHLLLRAHLDPPGGR
. : . .: .::.. * :.. . * * . :. .
Mflv_1873|M.gilvum_PYR-GCK FAPAVFLWFAGIGGLTVVMSGGVTPRVRKPKPEPVRDADPD-------AA
Mvan_4858|M.vanbaalenii_PYR-1 FAPAVFLWFFGIGALTVAMSGGITPRVRKPKPVPEPAAVVDDAVIETADA
MUL_4714|M.ulcerans_Agy99 LLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPVPPAEAD-------VD
MMAR_4544|M.marinum_M LLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPAPPVEAD-------VD
MLBr_00159|M.leprae_Br4923 LVVGVFFWFAVVGWVTVVVACGIKRFPRHLKPP--PALSS----------
MAV_1079|M.avium_104 LLVGVFFWFAVVGGATVVMSGGIRRPTRRLKPR--PAPAAP-------VA
Mb0980|M.bovis_AF2122/97 LVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPA--PPVELD-------AD
Rv0955|M.tuberculosis_H37Rv LVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPA--PPVELD-------AD
MSMEG_5517|M.smegmatis_MC2_155 FGPAVFLWFVGIGGLTVVMSGGIVRRVRVAPAAPPPAPEPE-------PE
MAB_1062|M.abscessus_ATCC_1997 FGPGVFFWFLVIGLLTVFMLGGATRLPARTRRDPEPAPEPE--------M
TH_2416|M.thermoresistible__bu LLEPAVVRTVLVTIAASLTAALIGQIADQLLGLEQLTANGG-------GA
: ... : :
Mflv_1873|M.gilvum_PYR-GCK DPDAAEFDDQADPDDQAELED--TASGDETPEPPTEEFAADPPP-----T
Mvan_4858|M.vanbaalenii_PYR-1 EPHTEEIALEAPPRDRPDPDPRIEPAGEPAPPVPDGPIDADLDPEDHFVV
MUL_4714|M.ulcerans_Agy99 EPIH-EPVDEPFVPLFDQDAPLDDVTSREPVAP--GGDDADVPP------
MMAR_4544|M.marinum_M EPIH-EPVDEPFVPLFDQDAPLGDMTSREPVAP--GGDDADVPP------
MLBr_00159|M.leprae_Br4923 EEH------------ADASS-KDHEAYFGVDLN--VPFDLS---------
MAV_1079|M.avium_104 EEHD-SVFGEAVGPVGDVAG-LDEIAAEGVDEV--AAEGVDESP------
Mb0980|M.bovis_AF2122/97 ESS------------PPVDM-FDGAASEQPPAS--VAEDVP---------
Rv0955|M.tuberculosis_H37Rv ESS------------PPVDM-FDGAASEQPPAS--VAEDVP---------
MSMEG_5517|M.smegmatis_MC2_155 PVVPGEVLGEPAEADEPDDEPFGDEPYEETPEEPLVSWHADEPP------
MAB_1062|M.abscessus_ATCC_1997 DPEP-----------APAPEPDPEPAPEPEPQR---EPEPESEP------
TH_2416|M.thermoresistible__bu GSLLRLLVLGLIMAPVIAAFLWFARVPEAEAAVAAVRRRFGKTP------
Mflv_1873|M.gilvum_PYR-GCK DRDPEPVPHDAVADTPPVDD-----LDPEE--HFVVDDDMGR-----NGG
Mvan_4858|M.vanbaalenii_PYR-1 DEQTSPFVEDEENGHFVEDEENGPFVEDEENGHFVEDEENGLSVVDDDSG
MUL_4714|M.ulcerans_Agy99 ---AAPDEVDWSDGPDR---------------------QDGPD----TSH
MMAR_4544|M.marinum_M ---AAPDEADWSDGPDRPDGP---------------DRQDGPD----ASH
MLBr_00159|M.leprae_Br4923 ------GEDEIPKAEPGEAA----------------D-------------
MAV_1079|M.avium_104 ---GDAGEREGDEGDPGERG----------------SGDAGAA----GER
Mb0980|M.bovis_AF2122/97 -----PSHDDIANGLKAPTA----------------DDEALPL----SDE
Rv0955|M.tuberculosis_H37Rv -----PSHDDIANGLKAPTA----------------DDEALPL----SDE
MSMEG_5517|M.smegmatis_MC2_155 ---EPAETDDDAGAPVAPRSPRDLLDEDPEDHFFVDEFGDEEV----SGD
MAB_1062|M.abscessus_ATCC_1997 -------EADTDEGPEIDPS-----------------------------D
TH_2416|M.thermoresistible__bu ----ASGPAPVTAGDRRCTG-----------------ADSQPGGDYRGRI
Mflv_1873|M.gilvum_PYR-GCK PPRDH----
Mvan_4858|M.vanbaalenii_PYR-1 GKREQGDH-
MUL_4714|M.ulcerans_Agy99 PPEHLT---
MMAR_4544|M.marinum_M PPEHLT---
MLBr_00159|M.leprae_Br4923 ---------
MAV_1079|M.avium_104 RPGE-----
Mb0980|M.bovis_AF2122/97 PPPRAD---
Rv0955|M.tuberculosis_H37Rv PPPRAD---
MSMEG_5517|M.smegmatis_MC2_155 KPRNAED--
MAB_1062|M.abscessus_ATCC_1997 PPESAK---
TH_2416|M.thermoresistible__bu PARSAFPVP