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M. leprae Br4923 MLBr_00159 (-)

annotation: hypothetical protein MLBr_00159
coordinates: 222677 - 223969
length: 430

VGDNRAAGVRQARDLVKVAFGPAVVALAIIAAITLLQLLIANSDMTGALGAIASMWLGVHQVPIAIGGRE
LSIMPLLPVLLMVWATAHSTSQATSAYSSWLVIRWVVASALGGPLLIAAISLAVIHDASSVLTELQTPKA
LRAFTGVLVVHAIGAAIGVNSRVGRRVLTASRLPDWVGDSVHAATAGVLALLGLSGLVTAGSLVVHWATM
QEFYGITDSIFGQFSLTVLSVLYAPNVIVGTSAVAVGSSAHLGFATFSSFTVFGGDIPALPVLAAAPTPP
LAPVWVALLIVGAASGVAVGQQCTRHPLPLLAALAKLLVAAATGALMMALLGYAGSGRLGNFGDIDVDQG
ALVVGVFFWFAVVGWVTVVVACGIKRFPRHLKPPPALSSEEHADASSKDHEAYFGVDLNVPFDLSGEDEI
PKAEPGEAAD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00159--100% (430)hypothetical protein MLBr_00159

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0980-1e-17675.89% (419) integral membrane protein
M. gilvum PYR-GCKMflv_1873-1e-14862.85% (428) hypothetical protein Mflv_1873
M. tuberculosis H37RvRv0955-1e-17675.89% (419) integral membrane protein
M. abscessus ATCC 19977MAB_1062-1e-13359.54% (388) hypothetical protein MAB_1062
M. marinum MMMAR_4544-1e-17471.88% (441) integral membrane protein
M. avium 104MAV_1079-1e-17874.83% (429) hypothetical protein MAV_1079
M. smegmatis MC2 155MSMEG_5517-1e-15468.12% (414) hypothetical protein MSMEG_5517
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4714-1e-17376.56% (401) integral membrane protein
M. vanbaalenii PYR-1Mvan_4858-1e-14764.81% (432) hypothetical protein Mvan_4858

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1873|M.gilvum_PYR-GCK          -------MSTRPVGTRQARDLLRVAFGPSIVALVIIAAIVLLQLLIANSD
Mvan_4858|M.vanbaalenii_PYR-1       -------MSTRPVGTRQARDLLRVAFGPSLVALVIIAAVVLLQLLIANSD
Mb0980|M.bovis_AF2122/97            MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSD
Rv0955|M.tuberculosis_H37Rv         MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSD
MLBr_00159|M.leprae_Br4923          ------MGDNRAAGVRQARDLVKVAFGPAVVALAIIAAITLLQLLIANSD
MAV_1079|M.avium_104                ------MEDNRAAGARQARDLVRVAFAPAVVALVIIAAVTLIQLLIANSD
MMAR_4544|M.marinum_M               ---MTRVEDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSD
MUL_4714|M.ulcerans_Agy99           ------MEDSRAAGARQARDLVKVAFAPAVVALVIIAAVTLIQLVIANSD
MSMEG_5517|M.smegmatis_MC2_155      -------MNNGPVGTRQARELLRVAFGPSVVALVIIAAVVLLQLVIANSD
MAB_1062|M.abscessus_ATCC_1997      ------MNQPSRANPAQARALLTVAFGPSAVALVIIAAIVLVQLVIANSD
                                            .   ..   ** *: ***.*. *** ****:.*:**:*****

Mflv_1873|M.gilvum_PYR-GCK          MTGALGAIASIWLGVHQVPVSIAGTALGVMPLLPVLLMIYGTARTTAAAT
Mvan_4858|M.vanbaalenii_PYR-1       MTGAFGAIASMWLGVHLVPVSIGGSALGVMPLLPVLVMIYGTARTTAAAT
Mb0980|M.bovis_AF2122/97            MTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARAT
Rv0955|M.tuberculosis_H37Rv         MTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARAT
MLBr_00159|M.leprae_Br4923          MTGALGAIASMWLGVHQVPIAIGGRELSIMPLLPVLLMVWATAHSTSQAT
MAV_1079|M.avium_104                MTGALGAIASMWLGVHQVPVSIGGRELGVLPLLPVLLMVWATARNTARAT
MMAR_4544|M.marinum_M               MTGALGAIASMWLGVHQVPISIGGRELGVMPLFPALLMVWGTARTTALAT
MUL_4714|M.ulcerans_Agy99           MTGALGAIASMWLGVHQVPISIGGRELGVMPLFPAMLMVWGTARTTALAT
MSMEG_5517|M.smegmatis_MC2_155      MTGAFGAIASMWLGVHQVPVSIGGRELGVMPLLPVLAMVWGTAKTTAAAT
MAB_1062|M.abscessus_ATCC_1997      MTGTFGAVASMWLGTHLVPISIGGRVIEVLPLLPTAAMVWGVARTVASAL
                                    ***: **:**:***.* **::*.*  : ::**:*.  *::..*:..: * 

Mflv_1873|M.gilvum_PYR-GCK          TST-SWFVTRWVVASALGGPILFTAICLAVIHDAASVLTELQTPDATRAF
Mvan_4858|M.vanbaalenii_PYR-1       SS--SWFVTRWVVASALGGPVLIAAICLAVIHDAASVLTQLQTPDALHAF
Mb0980|M.bovis_AF2122/97            SPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAF
Rv0955|M.tuberculosis_H37Rv         SPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAF
MLBr_00159|M.leprae_Br4923          SAYSSWLVIRWVVASALGGPLLIAAISLAVIHDASSVLTELQTPKALRAF
MAV_1079|M.avium_104                SPHSSWLVIRWVVASALGGPLLMTAVALAVIHDASSVITELQTPSALRAF
MMAR_4544|M.marinum_M               SPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTPSALRAF
MUL_4714|M.ulcerans_Agy99           SPYSSWLVVRWVIASALGGPLLIAAICLAVIHDASSVITELQTPNALRAF
MSMEG_5517|M.smegmatis_MC2_155      APNSSWFVTRWVVASALGGPLLIAALLLAVIHDAASVITELQTPSALRAF
MAB_1062|M.abscessus_ATCC_1997      APTTSWYVIRWVIASALAGPLLMTAISLAIIHDASTVLTQLQSPNALRAF
                                    :.  *  * ***:****.**:*::*: **:****::*:*:**:*.* :**

Mflv_1873|M.gilvum_PYR-GCK          GGVFVVHLIGAVLGVGSRLGPRLLALSRLPAWIPDALRGAAAGVIALMGL
Mvan_4858|M.vanbaalenii_PYR-1       GYVFTVHAIGAVLGVGSRVGRRLLSASPLPGWLPDAFRAAAAGVLALMGL
Mb0980|M.bovis_AF2122/97            TSVLVVHSVGAATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGL
Rv0955|M.tuberculosis_H37Rv         TSVLVVHSVGAATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGL
MLBr_00159|M.leprae_Br4923          TGVLVVHAIGAAIGVNSRVGRRVLTASRLPDWVGDSVHAATAGVLALLGL
MAV_1079|M.avium_104                LSVLVVHAIGAGIGVWSQVGPRALAASSLPYWLGDSLRAATAGVLALLGL
MMAR_4544|M.marinum_M               VSVLAVHAIGAGLGVWSRVGRRALAVSPLPNWLGDSLRAAAAGVLALLGL
MUL_4714|M.ulcerans_Agy99           VSVLAVHAIGAGLGVWSRVGIRALAVSPLPNWLGDSLRAAAAGVLALLGL
MSMEG_5517|M.smegmatis_MC2_155      GGVLAVHAIGALIGVSTKIGRRTLAASPLPKWLPDAVRAASAGVLALFAL
MAB_1062|M.abscessus_ATCC_1997      GCVLGVHAVGAVIGVVTRVGRRIALVLQLPSWPMDAARGAVAGVLALFGL
                                      *: ** :**  ** :::* *      ** *  *: :.* ***:**:.*

Mflv_1873|M.gilvum_PYR-GCK          SGAAVAGSLIVHWSTMHDLYSITESMFGQFSLTVLSVLYLPNIVIGAAAV
Mvan_4858|M.vanbaalenii_PYR-1       SGAVVAGSLVVHWSTMHDLFSITDSMFGQLSLTVLSVLYLPNVMVGASAV
Mb0980|M.bovis_AF2122/97            SGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAI
Rv0955|M.tuberculosis_H37Rv         SGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAI
MLBr_00159|M.leprae_Br4923          SGLVTAGSLVVHWATMQEFYGITDSIFGQFSLTVLSVLYAPNVIVGTSAV
MAV_1079|M.avium_104                SGFVTAGSLVVHWATMQELYGITDSIFGEFSLTVLSMLYAPNVIVGTAAV
MMAR_4544|M.marinum_M               SGLVTAGSLVVHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAI
MUL_4714|M.ulcerans_Agy99           SGLVTAGSLVVHWATMQELYGITDSAFGQFSLTVLSVLYVPNVVVGAAAI
MSMEG_5517|M.smegmatis_MC2_155      SGIVTAGSLVVHWGTMHDLFAITDTVFGQLSLTGLSVLYIPNVIVGTSAI
MAB_1062|M.abscessus_ATCC_1997      SGAVTAGSLVVHWATMDQLYSVTNDFVGQLSLTLLAILYAPNVILGSCAL
                                    ** ..****:***.**.:::.:*:  .*::*** *::** **:::*:.*:

Mflv_1873|M.gilvum_PYR-GCK          AVGSSAHIGLATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAV
Mvan_4858|M.vanbaalenii_PYR-1       AVGSSAHIGLATFSSFTVFGGDIPALPVLAAVPTPPLGPVWVALMIIAAV
Mb0980|M.bovis_AF2122/97            AVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGAS
Rv0955|M.tuberculosis_H37Rv         AVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGAS
MLBr_00159|M.leprae_Br4923          AVGSSAHLGFATFSSFTVFGGDIPALPVLAAAPTPPLAPVWVALLIVGAA
MAV_1079|M.avium_104                AVGSSAHIGFATFSSFTVFGGDIPALPVLAAVPRPPLGPVWVALLIIGAS
MMAR_4544|M.marinum_M               AVGASAHIGFATFSAFTVFGGDIPAVPILAAAPTPLLGPVWVALLIIGAS
MUL_4714|M.ulcerans_Agy99           AVGASAHIGFATFSAFTVFGGDIPAVPILAAAPTPPLGPVWVALLIIGAS
MSMEG_5517|M.smegmatis_MC2_155      AVGSSAHIGLATFSSFTVFGGDIPAVPVLAAAPTPPLGPVWVALLIVGAA
MAB_1062|M.abscessus_ATCC_1997      AVGSSAHVGTATFSAFAVFGGQLPAVPILAAVPTPPLGPAWVALMIIGAV
                                    ***:***:* ****:*:*:**::**:*:***.* * *.*.****:*:.* 

Mflv_1873|M.gilvum_PYR-GCK          SAVALGQQCARRPLPLVTALAKVVVAATVAAATMALLGFAGGGALGNFGQ
Mvan_4858|M.vanbaalenii_PYR-1       SAVALGQQCARHPLPMPAALAKVLTAAAAAAGAMALLGHAGGGPLGNFGN
Mb0980|M.bovis_AF2122/97            SGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGD
Rv0955|M.tuberculosis_H37Rv         SGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGD
MLBr_00159|M.leprae_Br4923          SGVAVGQQCTRHPLPLLAALAKLLVAAATGALMMALLGYAGSGRLGNFGD
MAV_1079|M.avium_104                SGVAVGQQCARRPLPPVAAMVKLLAASVAGALVMSLLAYAGSGQLGNFGH
MMAR_4544|M.marinum_M               SGVAVGQQCARRPLPPLPAMGKLLAAALVGALAMALLGYGGSGKLGNFGA
MUL_4714|M.ulcerans_Agy99           SGVAVGQQCARRPLPPLPAMGKLLAAALLGALAMALLGYGGSGKLGNFGA
MSMEG_5517|M.smegmatis_MC2_155      SAVALGQQCAARPLTPFAALAKLIVASLISAVTMALLGYAGSGRLGNFGH
MAB_1062|M.abscessus_ATCC_1997      SGVAVGQQCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNFGR
                                    *.**:****: :.:.  .*: *::.*:  .*  ::::.  ..* ***** 

Mflv_1873|M.gilvum_PYR-GCK          VGVDQSTFAPAVFLWFAGIGGLTVVMSGGVTPRVRKPKPEPVRDADPD--
Mvan_4858|M.vanbaalenii_PYR-1       VGVDQATFAPAVFLWFFGIGALTVAMSGGITPRVRKPKPVPEPAAVVDDA
Mb0980|M.bovis_AF2122/97            VGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDA---
Rv0955|M.tuberculosis_H37Rv         VGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDA---
MLBr_00159|M.leprae_Br4923          IDVDQGALVVGVFFWFAVVGWVTVVVACGIKRFPRHLKPPPALSS-----
MAV_1079|M.avium_104                VGVDQGALLVGVFFWFAVVGGATVVMSGGIRRPTRRLKPRPAPAAPV---
MMAR_4544|M.marinum_M               VGVDEGALLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPAPPVEADVD
MUL_4714|M.ulcerans_Agy99           VGVDEGALLVGVFFWFAVVGGATLVMAGGIRRRPRRPKPRPVPPAEADVD
MSMEG_5517|M.smegmatis_MC2_155      VGVDQSTFGPAVFLWFVGIGGLTVVMSGGIVRRVRVAPAAPPPAPEP---
MAB_1062|M.abscessus_ATCC_1997      LGIDQGTFGPGVFFWFLVIGLLTVFMLGGATRLPARTRRDPEPAPEP---
                                    :.:*:.::  .*::**  :*  *: :  *           *         

Mflv_1873|M.gilvum_PYR-GCK          -----AADPDAAEFDDQADPDDQAELED--TASGDETPEPPTEEFAADPP
Mvan_4858|M.vanbaalenii_PYR-1       VIETADAEPHTEEIALEAPPRDRPDPDPRIEPAGEPAPPVPDGPIDADLD
Mb0980|M.bovis_AF2122/97            -------DESS----------PPVDMFDGAASEQPPASVAEDVP------
Rv0955|M.tuberculosis_H37Rv         -------DESS----------PPVDMFDGAASEQPPASVAEDVP------
MLBr_00159|M.leprae_Br4923          -------EEH-----------ADASSKDHEAYFGVDLNVPFDLS------
MAV_1079|M.avium_104                ------AEEHDSVFGEAVGPVGDVAGLDEIAAEGVDEVAAEGVDES----
MMAR_4544|M.marinum_M               EPIHEPVDEPFVPLFDQDAPLGDMTSREPVAPGGDDADVPPAAP------
MUL_4714|M.ulcerans_Agy99           EPIHEPVDEPFVPLFDQDAPLDDVTSREPVAPGGDDADVPPAAP------
MSMEG_5517|M.smegmatis_MC2_155      -------EPEPVVPGEVLGEPAEADEPDDEPFGDEPYEETPEEPLVS---
MAB_1062|M.abscessus_ATCC_1997      ----------------------EMDPEPAPAPEPDPEPAPEPEP------
                                                                                      

Mflv_1873|M.gilvum_PYR-GCK          P-----TDRDPEPVPHDAVADTPPVDD-----LDPEE--HFVVDDDMGR-
Mvan_4858|M.vanbaalenii_PYR-1       PEDHFVVDEQTSPFVEDEENGHFVEDEENGPFVEDEENGHFVEDEENGLS
Mb0980|M.bovis_AF2122/97            ----------PSHDDIANGLKAPTADDEALPLSDEPPPRAD---------
Rv0955|M.tuberculosis_H37Rv         ----------PSHDDIANGLKAPTADDEALPLSDEPPPRAD---------
MLBr_00159|M.leprae_Br4923          -----------GEDEIPKAEPGEAAD------------------------
MAV_1079|M.avium_104                -------PGDAGEREGDEGDPGERGSGDAGAAGERRPGE-----------
MMAR_4544|M.marinum_M               -----------DEADWSDGPDRPDGPDRQDGPDASHPPEHLT--------
MUL_4714|M.ulcerans_Agy99           -----------DEVDWSDGPD------RQDGPDTSHPPEHLT--------
MSMEG_5517|M.smegmatis_MC2_155      ----WHADEPPEPAETDDDAGAPVAPRSPRDLLDEDPEDHFFVDEFGDEE
MAB_1062|M.abscessus_ATCC_1997      ----------QREPEPESEPEADTDEGPEIDPSDPPESAK----------
                                                                                      

Mflv_1873|M.gilvum_PYR-GCK          ----NGGPPRDH---
Mvan_4858|M.vanbaalenii_PYR-1       VVDDDSGGKREQGDH
Mb0980|M.bovis_AF2122/97            ---------------
Rv0955|M.tuberculosis_H37Rv         ---------------
MLBr_00159|M.leprae_Br4923          ---------------
MAV_1079|M.avium_104                ---------------
MMAR_4544|M.marinum_M               ---------------
MUL_4714|M.ulcerans_Agy99           ---------------
MSMEG_5517|M.smegmatis_MC2_155      VSGDKPRNAED----
MAB_1062|M.abscessus_ATCC_1997      ---------------