For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4362 (-)

annotation: PE-PGRS family protein
coordinates: 5367700 - 5369265
length: 521

VSFVIAEPELLAATATHLSSLRTTLVAANAAAAVPTTGLLAAADDEVSVAIAAGFRAYGQAYQALSTRAA
DVHARFVQALAAGADRYASAEAANAGQQLLDIVNAPTQALIGRPLIGNGTNGAPGTGQDGGPGGLLIGNG
GSGGSGAAGTNGGNGGAAGLLGAGGAGGVGGFGLPGGAGGNGGAGGAGGLFGNGGNGGTGGGSLDGNGGS
GGAGGAGGFLGSGGKGGVGGVSAHQVGGTGGPGGTGGLLGAGGAGGDGGQADDAIGGTGGTGGSGGTLYG
SGGLGGNGGNGGHQGGLGGAGGSGGLFGDGGSGGDGGTGGTNGAAGGAGGRGGLLYGSGGDGGDGGNGQP
ADGGAGGAGGAGGLLGAGGNGGDGGVGHDNGGAGGAGGRAGPLVGAGGNGGDGGAAGLHGGQGGGGGNAG
ILLGNGGAGGTGGWGGFSVPGQGGTGGAGGHAGLIGNGGNGGAGGITSVAGGTGGDGGKGGDAWVIGNGG
NGGSGGTGTQPGGPGVGGSGGSLIGQHGLNG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4362--100% (521)PE-PGRS family protein
M. marinum MMMAR_0478-e-15454.78% (544) PE-PGRS family protein
M. marinum MMMAR_0755-e-15053.20% (579) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1360cPE_PGRS241e-15753.11% (610) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-10348.18% (467) triple helix repeat-containing collagen
M. tuberculosis H37RvRv2741PE_PGRS471e-16459.29% (538) PE-PGRS family protein
M. leprae Br4923MLBr_01183-9e-1340.22% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-9e-4735.71% (434) hypothetical protein MAB_4284c
M. avium 104MAV_4827-5e-2444.32% (185) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-4e-8038.12% (627) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-4443.37% (309) PUTATIVE -
M. ulcerans Agy99MUL_0212-1e-15251.96% (637) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-10150.80% (437) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4362|M.marinum_M               --------------------------------------------------
MUL_0212|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           --------------------MSFVIAAPETLVRAASDLANIG--------
Rv2741|M.tuberculosis_H37Rv         --------------------MSFVIAAPEFLTAAAMDLASIG--------
MMAR_4362|M.marinum_M               --------------------MSFVIAEPELLAATATHLSSLR--------
MUL_0212|M.ulcerans_Agy99           --------------------MSFVNVTPEAVAAAASDLTGIG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG-
MAV_4827|M.avium_104                -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTG-----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           -------------------------------------STLGAANAAALGP
Rv2741|M.tuberculosis_H37Rv         -------------------------------------STVSAASAAASAP
MMAR_4362|M.marinum_M               -------------------------------------TTLVAANAAAAVP
MUL_0212|M.ulcerans_Agy99           -------------------------------------SVLGEANAVAARA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------LSAVSAAQVGAVMP
MAV_4827|M.avium_104                ---------------------------------ADDAATASAPDRVISAI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           --------------------------------------TTELLAAGADEV
Rv2741|M.tuberculosis_H37Rv         --------------------------------------TVAILAAGADEV
MMAR_4362|M.marinum_M               --------------------------------------TTGLLAAADDEV
MUL_0212|M.ulcerans_Agy99           --------------------------------------TTTVLAAGGDEV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------VVAESVASNYGYQ
MAV_4827|M.avium_104                LG------------------------------------TREGAADAGLQL
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           S---------------------AAIASLFAAHGQAYQAVSAQMSAFHAQF
Rv2741|M.tuberculosis_H37Rv         S---------------------IAVAALFGMHGQAYQALSVQASAFHQQF
MMAR_4362|M.marinum_M               S---------------------VAIAAGFRAYGQAYQALSTRAADVHARF
MUL_0212|M.ulcerans_Agy99           S---------------------AAIAALFSFHGQSYQTLGAQAEAFHAQF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SQWVN------------------TGNPIHDLSGNLQNYYAAQPDGPSILS
MAV_4827|M.avium_104                S----------------------SIGVTWTDQLEAAALRDALAARRIDNV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGG-----NGGNGGLFGGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGG-----NGGNAGLFGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGG-----NGGNAGLFG-NGGNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           VQTFTAGAGAYASAEAAAAAPLEGLLNIV-----NTPTQLLLGRPLIGNG
Rv2741|M.tuberculosis_H37Rv         VQALTAGAYSYASAEAAAVTPLQQLVDVI-----NAPFRSALGRPLIGNG
MMAR_4362|M.marinum_M               VQALAAGADRYASAEAANAG--QQLLDIV-----NAPTQALIGRPLIGNG
MUL_0212|M.ulcerans_Agy99           AQLMANGAGTYASAEAANAAPFQGLLGAV-----NAPVQTLTGRPLIGNG
MLBr_01183|M.leprae_Br4923          -------MPLFLNAEPQALTAAANTLEGL-----SAAT--VASNAAAAQL
MAB_4284c|M.abscessus_ATCC_199      PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS
MAV_4827|M.avium_104                MLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          NGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGA
Mvan_1264|M.vanbaalenii_PYR-1       NGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGA
MSMEG_0868|M.smegmatis_MC2_155      VGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGT
TH_3810|M.thermoresistible__bu      ---VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGH
Mb1360c|M.bovis_AF2122/97           ANGAPGTGQAGGAGG--LLYGNGGAGGSGAPG-------------QAGGP
Rv2741|M.tuberculosis_H37Rv         ANGKPGTGQDGGAGG--LLYGSGGNGGSGLAGS-----------GQKGGN
MMAR_4362|M.marinum_M               TNGAPGTGQDGGPGG--LLIGNGGSGGSGAAG-------------TNGGN
MUL_0212|M.ulcerans_Agy99           ANGAPGTGANGGAGG--WLIGNGGAGGSGAPG-------------LNGGA
MLBr_01183|M.leprae_Br4923          TTEIAPPAADDVSILLAHFFSGHGRQYQAHAS---------------QGA
MAB_4284c|M.abscessus_ATCC_199      FGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQG---------STAVNGD
MAV_4827|M.avium_104                YKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG----------LLLVGSG
                                                                   .                . 

Mflv_5091|M.gilvum_PYR-GCK          TGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1       TGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG----------
MSMEG_0868|M.smegmatis_MC2_155      GGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIA
TH_3810|M.thermoresistible__bu      GGGTGIIS--------------------LLSLAGNGGNGG----------
Mb1360c|M.bovis_AF2122/97           GGAAGLFGNGGAGG------AGG-DGPGNGAAGGAGGAGG----------
Rv2741|M.tuberculosis_H37Rv         GGAAGLFGNGGAGG------AGASNQAGNGGAGGNGGAGG----------
MMAR_4362|M.marinum_M               GGAAGLLGAGGAGG------VGG--------FGLPGGAG-----------
MUL_0212|M.ulcerans_Agy99           GGAAGLIGTGGAGG------AGGSSSTVNGGLGGTGGAGG----------
MLBr_01183|M.leprae_Br4923          TNHQDLIQS---------------------LLTSSSAYAG----------
MAB_4284c|M.abscessus_ATCC_199      VRDSNIINADHGSN----VGVDQSQTRVGGDYTNVSGHGS----------
MAV_4827|M.avium_104                VDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP----------
                                                                       .. .           

Mflv_5091|M.gilvum_PYR-GCK          ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-----------
MSMEG_0868|M.smegmatis_MC2_155      GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG
TH_3810|M.thermoresistible__bu      -----NGYRTTDNNALDGGHGG----------------------------
Mb1360c|M.bovis_AF2122/97           ---------LLFGSGGAGGPGGVGN-------------------------
Rv2741|M.tuberculosis_H37Rv         ---------LIWGTAGTGGNGGFTTF------------------------
MMAR_4362|M.marinum_M               ------------GNGGAGGAG-----------------------------
MUL_0212|M.ulcerans_Agy99           ---------WLLGNGGAGGAGGASAIPLGPDLIGKGGAG-----------
MLBr_01183|M.leprae_Br4923          -----------TETANHDSL------------------------------
MAB_4284c|M.abscessus_ATCC_199      --ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGN-----------
MAV_4827|M.avium_104                ---LFASSTAALAYAQDPGTGAVDQYSLP---------------------
                                                      .                               

Mflv_5091|M.gilvum_PYR-GCK          -----AVGAAGAAG------TVGTAGATGGTG---------------TGA
Mvan_1264|M.vanbaalenii_PYR-1       -----AIGTAGVAG------AAGTAGATGGTG---------------VGG
MSMEG_0868|M.smegmatis_MC2_155      TVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGG
TH_3810|M.thermoresistible__bu      -----------------------------------------------NGG
Mb1360c|M.bovis_AF2122/97           --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4362|M.marinum_M               --------------------------------------------------
MUL_0212|M.ulcerans_Agy99           -------------------------------------------------G
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------------TTNT
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          NGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGG
Mvan_1264|M.vanbaalenii_PYR-1       NGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGG
MSMEG_0868|M.smegmatis_MC2_155      DGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGG
TH_3810|M.thermoresistible__bu      NVGFFSLFNLGG--------------------AGGWGGSGVDG-------
Mb1360c|M.bovis_AF2122/97           ----TGTGGLGGDGG-----------------AAGLFGAGGIGGAGG---
Rv2741|M.tuberculosis_H37Rv         ---LDAAGGAGGAGG-----------------AGGLFGAGGAGGVGG---
MMAR_4362|M.marinum_M               --GLFGNGGNGGTG------------------GGSLDGNGGSGGAG----
MUL_0212|M.ulcerans_Agy99           PGGLFGAGGLGGAGGF----------------GGSGGGAGGQGGAGGLLS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EIGSHNQANIGTSTS-----------------AGGSAAVGGNAGLAG---
MAV_4827|M.avium_104                DYLYVPVDPEPGDDE----------------LAYSAVGEEDAESPTVVIE
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          VGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG------
Mvan_1264|M.vanbaalenii_PYR-1       IGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG------
MSMEG_0868|M.smegmatis_MC2_155      MGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGK
TH_3810|M.thermoresistible__bu      --------------VDVVGGNP----------------------------
Mb1360c|M.bovis_AF2122/97           --------PGFNGGAGGAGGRSGLFEVLAAGGAG----------------
Rv2741|M.tuberculosis_H37Rv         --------AALGGGAQAAGG------------------------------
MMAR_4362|M.marinum_M               ---------GAGG-FLGSGG---------KGG-V----------------
MUL_0212|M.ulcerans_Agy99           ------GLVGAGGGHGGTGG---------YGGGA----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------NAGLAGNAGLAGNAGLAGNAGLAGNAG----------------
MAV_4827|M.avium_104                KLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALE----------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------LQGGKGGDGGAGGKGGDADSMGS------------------AG
Mvan_1264|M.vanbaalenii_PYR-1       -------LQGGQGGDGGTGGTGGDATSMGE------------------AG
MSMEG_0868|M.smegmatis_MC2_155      ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS
TH_3810|M.thermoresistible__bu      --------------DGGTPG------------------------------
Mb1360c|M.bovis_AF2122/97           -------GTGGLSVNGGTGGTGGTGG-GGG------------------LF
Rv2741|M.tuberculosis_H37Rv         --------------NGGAGGVG-------G------------------LF
MMAR_4362|M.marinum_M               -------GGVSAHQVGGTGGPGGTGG----------------------LL
MUL_0212|M.ulcerans_Agy99           -------GGAGATGGGNTGGIGGDGGSAGM------------------LF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------LAGNAGLAGNAGLAGNAGLAGNAG----------------LA
MAV_4827|M.avium_104                --------IALAIGIRTTGTVALQPTPNQH-----------------LIV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD------
Mvan_1264|M.vanbaalenii_PYR-1       ATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN------
MSMEG_0868|M.smegmatis_MC2_155      ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY
TH_3810|M.thermoresistible__bu      AHGESHTPGVYTDRQ-----------------------------------
Mb1360c|M.bovis_AF2122/97           SNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGAGGTGTG-----
Rv2741|M.tuberculosis_H37Rv         GAGGAGGAGGFSDTG-----------------------------------
MMAR_4362|M.marinum_M               GAGGAGGDGGQADDAIG---------------------------------
MUL_0212|M.ulcerans_Agy99           SNSGAGGAGGASELADG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAG-------------------------------
MAV_4827|M.avium_104                PTEQAPAPPPVQASAPQPK-------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------GGTGGAGGAGGTGG-TGGAGGTGG----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------GGTGGNGGNGGTGG-TGGNGGTGG----------
MSMEG_0868|M.smegmatis_MC2_155      DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ
TH_3810|M.thermoresistible__bu      --------------------GEDGEDGTGTGIGGRGGNGG----------
Mb1360c|M.bovis_AF2122/97           ---------------NQLVGGEGGAGGAGGNAGILFGAGG----------
Rv2741|M.tuberculosis_H37Rv         --------------------GTGGAGGAGG----LFGPG-----------
MMAR_4362|M.marinum_M               --------------------GTGGTGGSGG---TLYGSGG----------
MUL_0212|M.ulcerans_Agy99           --------------------GAGGAGGNGG---WLLSNGG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------NAGLAGNAGLAGNAGLAGNAG-----------
MAV_4827|M.avium_104                ---------------ISVPEPVAAPKPLSPPVAAPLPAAP----------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      HSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGH
TH_3810|M.thermoresistible__bu      ------SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSH
Mb1360c|M.bovis_AF2122/97           -------IGGTGGTGLGAPDP--GGTGGKGGVGGIGGAGA---LFGPGGA
Rv2741|M.tuberculosis_H37Rv         --------GGSGGVG---------GFGDTGGTGGDGGSGG---LFGVGGA
MMAR_4362|M.marinum_M               -------LGGNGGNGGHQGG-----------LGGAGGSGG---LFGDGGS
MUL_0212|M.ulcerans_Agy99           -------VGGAGGAGADAVGPPFGIPAGSGSGGGAGGAGG--VFFGNGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAV
MAV_4827|M.avium_104                -------PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGTGGKGG------TGGTGGAGGTG----GDGGTGGTGGTGGTG------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGKGG------TGGTGGDGGTG----GTGGTGGTGGTGGTG------
MSMEG_0868|M.smegmatis_MC2_155      GGDGGRGG------DGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDP
TH_3810|M.thermoresistible__bu      GGNGGHGG------RGGFLGIGGSG-------GWGGHGGNGGD-------
Mb1360c|M.bovis_AF2122/97           GGTGGFGASSADQMAGGIGGSGGSGGA-AKLIGDGGAGGTGGD-------
Rv2741|M.tuberculosis_H37Rv         GGHGGFGS-----AAGGDGGAGGAGG---TVFGSGGAGGAGG--------
MMAR_4362|M.marinum_M               GGDGGTGG-----TNGAAGGAGGRG---GLLYGSGGDGGDGGN-------
MUL_0212|M.ulcerans_Agy99           GGAGGTGG-----DGGGTGGAGGAAGN-GVLIGNGGNGGIGGAA------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAAVGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVGGST------
MAV_4827|M.avium_104                SPPQLLAP-----PRLSVPQPVQPPVRVPQPPSPPQVGGTVPQS------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGG
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGG
MSMEG_0868|M.smegmatis_MC2_155      SHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGG
TH_3810|M.thermoresistible__bu      ----TDADGGNGGDG---------------GNGGSAG-------------
Mb1360c|M.bovis_AF2122/97           ---------SVRGAA---------------GSGGTGG-------TGGLIG
Rv2741|M.tuberculosis_H37Rv         ----------VATVA---------------GHGGHGGN------AGLLYG
MMAR_4362|M.marinum_M               ------GQPADGGAG---------------GAGGAG---------GLLG-
MUL_0212|M.ulcerans_Agy99           ------GLWGTGGTG---------------GSGGSGGTGATGGFSGLLAS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------AVGGGAHTG--------------VGGGVSTGVGVGSHVGGGISE
MAV_4827|M.avium_104                -------PPQHQTPP---------------GEGTPPK-------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          QGG-----------------TGGTGGQGG--------LGGGGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1       QGG-----------------TGGTGGQGG--------LGGVGGTG-----
MSMEG_0868|M.smegmatis_MC2_155      DGGEALIRATVIGSNASGTATGGDGGNGGT-------LGATNGTGGAATI
TH_3810|M.thermoresistible__bu      --------------------RGGTGGLRGV-------FGINGGNG-----
Mb1360c|M.bovis_AF2122/97           --------------------DGGAGGAGGTGIE----FGSVGGAG-----
Rv2741|M.tuberculosis_H37Rv         --------------------TGGAGGAGG--------FGGFGGDG-----
MMAR_4362|M.marinum_M               --------------------AGGNGGDGGVG-------HDNGGAG-----
MUL_0212|M.ulcerans_Agy99           GDG----------------GAGGAGGAGGAGGLLDGLVGAGGGDG-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      S-------------------LGGSGSVGG---------STAVGGG-----
MAV_4827|M.avium_104                --------------------PDGPGNYGGGHVP----TPGAGGSG-----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------GQGGTGGTGGQGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GTGGTGGTGGQGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155      VAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI
TH_3810|M.thermoresistible__bu      -------------------RAGLGGRGXXXXGGGVGAAVRSG--------
Mb1360c|M.bovis_AF2122/97           --------------------GAGGNAAGLSGAGGAGGAGGFG--------
Rv2741|M.tuberculosis_H37Rv         --------------------GDGG-IGGLVGSGGAGGSGGTG--------
MMAR_4362|M.marinum_M               --------------------GAGGRAGPLVGAGGNGGDGGAA--------
MUL_0212|M.ulcerans_Agy99           --------------------GAGGNAGTLFGSGGVGGDGGSG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------AHTGVGGGVSTGVGVGSHVGGG--------
MAV_4827|M.avium_104                --------------------GSGGGHVPTPGAGGSGGSGGGHVP------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGT
Mvan_1264|M.vanbaalenii_PYR-1       GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGV
MSMEG_0868|M.smegmatis_MC2_155      GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGT
TH_3810|M.thermoresistible__bu      -------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------
Mb1360c|M.bovis_AF2122/97           -----ETAGD-GGAGGN--AGLLNGDGGAG---GAGGLGIAGDG------
Rv2741|M.tuberculosis_H37Rv         -----TLSGGRGGAGGN--AGTFYGSGGAG---GAGGESDNGDG------
MMAR_4362|M.marinum_M               -----GLHGGQGGGGGN--AGILLGNGGAGGTGGWGGFSVPGQG------
MUL_0212|M.ulcerans_Agy99           -----HGNGGDGGGGGN--AGLLFSDAGGG---GFGGFGLAGGG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---ISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGG------
MAV_4827|M.avium_104                ----TPGTGGPGGTGGS--GGGHVPTPGAGTPGGSGGGHLPFPG------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG-----
Mvan_1264|M.vanbaalenii_PYR-1       AGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG-----
MSMEG_0868|M.smegmatis_MC2_155      ASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV
TH_3810|M.thermoresistible__bu      ------------------IMPSSRAASARAG-------------------
Mb1360c|M.bovis_AF2122/97           ---------------------GNGGKGGKAG-------------------
Rv2741|M.tuberculosis_H37Rv         ---------------------GNGGVGGKAG-------------------
MMAR_4362|M.marinum_M               ---------------------GTGGAGGHAG-------------------
MUL_0212|M.ulcerans_Agy99           ---------------------GTGGSGGDAG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------GISESLGGSGS-------------------
MAV_4827|M.avium_104                ---------------------AGSTPGGSGG-------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGS
Mvan_1264|M.vanbaalenii_PYR-1       -AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGS
MSMEG_0868|M.smegmatis_MC2_155      MAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAI
TH_3810|M.thermoresistible__bu      --------AACASSTSRSRRSFCCSRA-----------------------
Mb1360c|M.bovis_AF2122/97           --------MVGNGGDGGAGGASV---------------------------
Rv2741|M.tuberculosis_H37Rv         --------LVGEGGNGGDGGATI---------------------------
MMAR_4362|M.marinum_M               --------LIGNGGNGGAGGITS---------------------------
MUL_0212|M.ulcerans_Agy99           --------WLGSGGAGGAGGISVNGDAG------------------AGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------VGGSTAVGGGAHTSAINDALG---------------------
MAV_4827|M.avium_104                ----------GHLPTPGAG-------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1       AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155      SGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4362|M.marinum_M               --------------------------------------------------
MUL_0212|M.ulcerans_Agy99           GGTSGQLLGDGGAGGAG----------------------------GEAEL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          SG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-------
Mvan_1264|M.vanbaalenii_PYR-1       VD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-------
MSMEG_0868|M.smegmatis_MC2_155      TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb1360c|M.bovis_AF2122/97           --VANGGVGGSGG-----------NATLIGNGGNGGNGGVGSA-------
Rv2741|M.tuberculosis_H37Rv         --AGKGGSGGNGG-----------NAWLTGQGGNGGNAAFGKAG------
MMAR_4362|M.marinum_M               VAGGTGGDGGKGG-----------DAWVIGNGGNGGSGGTGTQ-------
MUL_0212|M.ulcerans_Agy99           AAGGAGGSGGVGG-----------DAVLIGAGGNGGNGGPGTA-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSS-------
MAV_4827|M.avium_104                --TPGGGLGGFGG-----------GHAPAPGGGLGGGGGHAPAP------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       -GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      -----------------------------------------------
Mb1360c|M.bovis_AF2122/97           -PGKGGAGGTAGLL-GLNGSPGLS-----------------------
Rv2741|M.tuberculosis_H37Rv         -TGSVGVGGAGGLLEGQNGENGLLPS---------------------
MMAR_4362|M.marinum_M               -PGGPGVGGSGGSLIGQHGLNG-------------------------
MUL_0212|M.ulcerans_Agy99           -KGDPGSGGAGG-LLGVDGLNGLS-----------------------
MLBr_01183|M.leprae_Br4923          -----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -MGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-----------
MAV_4827|M.avium_104                -GGGLGGFGGGHSGGGLGGLGGGHK----------------------