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VSFVIAEPELLAATATHLSSLRTTLVAANAAAAVPTTGLLAAADDEVSVAIAAGFRAYGQAYQALSTRAA DVHARFVQALAAGADRYASAEAANAGQQLLDIVNAPTQALIGRPLIGNGTNGAPGTGQDGGPGGLLIGNG GSGGSGAAGTNGGNGGAAGLLGAGGAGGVGGFGLPGGAGGNGGAGGAGGLFGNGGNGGTGGGSLDGNGGS GGAGGAGGFLGSGGKGGVGGVSAHQVGGTGGPGGTGGLLGAGGAGGDGGQADDAIGGTGGTGGSGGTLYG SGGLGGNGGNGGHQGGLGGAGGSGGLFGDGGSGGDGGTGGTNGAAGGAGGRGGLLYGSGGDGGDGGNGQP ADGGAGGAGGAGGLLGAGGNGGDGGVGHDNGGAGGAGGRAGPLVGAGGNGGDGGAAGLHGGQGGGGGNAG ILLGNGGAGGTGGWGGFSVPGQGGTGGAGGHAGLIGNGGNGGAGGITSVAGGTGGDGGKGGDAWVIGNGG NGGSGGTGTQPGGPGVGGSGGSLIGQHGLNG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4362 | - | - | 100% (521) | PE-PGRS family protein |
M. marinum M | MMAR_0478 | - | e-154 | 54.78% (544) | PE-PGRS family protein |
M. marinum M | MMAR_0755 | - | e-150 | 53.20% (579) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | 1e-157 | 53.11% (610) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-103 | 48.18% (467) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv2741 | PE_PGRS47 | 1e-164 | 59.29% (538) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 9e-13 | 40.22% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 9e-47 | 35.71% (434) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 5e-24 | 44.32% (185) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-80 | 38.12% (627) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-44 | 43.37% (309) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0212 | - | 1e-152 | 51.96% (637) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-101 | 50.80% (437) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 -------------------------------------------------- Rv2741|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4362|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 --------------------MSFVIAAPETLVRAASDLANIG-------- Rv2741|M.tuberculosis_H37Rv --------------------MSFVIAAPEFLTAAAMDLASIG-------- MMAR_4362|M.marinum_M --------------------MSFVIAEPELLAATATHLSSLR-------- MUL_0212|M.ulcerans_Agy99 --------------------MSFVNVTPEAVAAAASDLTGIG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG- MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTG----- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 -------------------------------------STLGAANAAALGP Rv2741|M.tuberculosis_H37Rv -------------------------------------STVSAASAAASAP MMAR_4362|M.marinum_M -------------------------------------TTLVAANAAAAVP MUL_0212|M.ulcerans_Agy99 -------------------------------------SVLGEANAVAARA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LSAVSAAQVGAVMP MAV_4827|M.avium_104 ---------------------------------ADDAATASAPDRVISAI Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 --------------------------------------TTELLAAGADEV Rv2741|M.tuberculosis_H37Rv --------------------------------------TVAILAAGADEV MMAR_4362|M.marinum_M --------------------------------------TTGLLAAADDEV MUL_0212|M.ulcerans_Agy99 --------------------------------------TTTVLAAGGDEV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------VVAESVASNYGYQ MAV_4827|M.avium_104 LG------------------------------------TREGAADAGLQL Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 S---------------------AAIASLFAAHGQAYQAVSAQMSAFHAQF Rv2741|M.tuberculosis_H37Rv S---------------------IAVAALFGMHGQAYQALSVQASAFHQQF MMAR_4362|M.marinum_M S---------------------VAIAAGFRAYGQAYQALSTRAADVHARF MUL_0212|M.ulcerans_Agy99 S---------------------AAIAALFSFHGQSYQTLGAQAEAFHAQF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SQWVN------------------TGNPIHDLSGNLQNYYAAQPDGPSILS MAV_4827|M.avium_104 S----------------------SIGVTWTDQLEAAALRDALAARRIDNV Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGG-----NGGNGGLFGGNGGNGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGG-----NGGNAGLFGGNGGNGG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGG-----NGGNAGLFG-NGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 VQTFTAGAGAYASAEAAAAAPLEGLLNIV-----NTPTQLLLGRPLIGNG Rv2741|M.tuberculosis_H37Rv VQALTAGAYSYASAEAAAVTPLQQLVDVI-----NAPFRSALGRPLIGNG MMAR_4362|M.marinum_M VQALAAGADRYASAEAANAG--QQLLDIV-----NAPTQALIGRPLIGNG MUL_0212|M.ulcerans_Agy99 AQLMANGAGTYASAEAANAAPFQGLLGAV-----NAPVQTLTGRPLIGNG MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEGL-----SAAT--VASNAAAAQL MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS MAV_4827|M.avium_104 MLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDV Mflv_5091|M.gilvum_PYR-GCK NGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGA Mvan_1264|M.vanbaalenii_PYR-1 NGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGA MSMEG_0868|M.smegmatis_MC2_155 VGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGT TH_3810|M.thermoresistible__bu ---VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGH Mb1360c|M.bovis_AF2122/97 ANGAPGTGQAGGAGG--LLYGNGGAGGSGAPG-------------QAGGP Rv2741|M.tuberculosis_H37Rv ANGKPGTGQDGGAGG--LLYGSGGNGGSGLAGS-----------GQKGGN MMAR_4362|M.marinum_M TNGAPGTGQDGGPGG--LLIGNGGSGGSGAAG-------------TNGGN MUL_0212|M.ulcerans_Agy99 ANGAPGTGANGGAGG--WLIGNGGAGGSGAPG-------------LNGGA MLBr_01183|M.leprae_Br4923 TTEIAPPAADDVSILLAHFFSGHGRQYQAHAS---------------QGA MAB_4284c|M.abscessus_ATCC_199 FGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQG---------STAVNGD MAV_4827|M.avium_104 YKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG----------LLLVGSG . . Mflv_5091|M.gilvum_PYR-GCK TGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG---------- Mvan_1264|M.vanbaalenii_PYR-1 TGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG---------- MSMEG_0868|M.smegmatis_MC2_155 GGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIA TH_3810|M.thermoresistible__bu GGGTGIIS--------------------LLSLAGNGGNGG---------- Mb1360c|M.bovis_AF2122/97 GGAAGLFGNGGAGG------AGG-DGPGNGAAGGAGGAGG---------- Rv2741|M.tuberculosis_H37Rv GGAAGLFGNGGAGG------AGASNQAGNGGAGGNGGAGG---------- MMAR_4362|M.marinum_M GGAAGLLGAGGAGG------VGG--------FGLPGGAG----------- MUL_0212|M.ulcerans_Agy99 GGAAGLIGTGGAGG------AGGSSSTVNGGLGGTGGAGG---------- MLBr_01183|M.leprae_Br4923 TNHQDLIQS---------------------LLTSSSAYAG---------- MAB_4284c|M.abscessus_ATCC_199 VRDSNIINADHGSN----VGVDQSQTRVGGDYTNVSGHGS---------- MAV_4827|M.avium_104 VDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP---------- .. . Mflv_5091|M.gilvum_PYR-GCK ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------- MSMEG_0868|M.smegmatis_MC2_155 GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG TH_3810|M.thermoresistible__bu -----NGYRTTDNNALDGGHGG---------------------------- Mb1360c|M.bovis_AF2122/97 ---------LLFGSGGAGGPGGVGN------------------------- Rv2741|M.tuberculosis_H37Rv ---------LIWGTAGTGGNGGFTTF------------------------ MMAR_4362|M.marinum_M ------------GNGGAGGAG----------------------------- MUL_0212|M.ulcerans_Agy99 ---------WLLGNGGAGGAGGASAIPLGPDLIGKGGAG----------- MLBr_01183|M.leprae_Br4923 -----------TETANHDSL------------------------------ MAB_4284c|M.abscessus_ATCC_199 --ADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGN----------- MAV_4827|M.avium_104 ---LFASSTAALAYAQDPGTGAVDQYSLP--------------------- . Mflv_5091|M.gilvum_PYR-GCK -----AVGAAGAAG------TVGTAGATGGTG---------------TGA Mvan_1264|M.vanbaalenii_PYR-1 -----AIGTAGVAG------AAGTAGATGGTG---------------VGG MSMEG_0868|M.smegmatis_MC2_155 TVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGG TH_3810|M.thermoresistible__bu -----------------------------------------------NGG Mb1360c|M.bovis_AF2122/97 -------------------------------------------------- Rv2741|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4362|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 -------------------------------------------------G MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------TTNT MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK NGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGG Mvan_1264|M.vanbaalenii_PYR-1 NGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGG MSMEG_0868|M.smegmatis_MC2_155 DGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGG TH_3810|M.thermoresistible__bu NVGFFSLFNLGG--------------------AGGWGGSGVDG------- Mb1360c|M.bovis_AF2122/97 ----TGTGGLGGDGG-----------------AAGLFGAGGIGGAGG--- Rv2741|M.tuberculosis_H37Rv ---LDAAGGAGGAGG-----------------AGGLFGAGGAGGVGG--- MMAR_4362|M.marinum_M --GLFGNGGNGGTG------------------GGSLDGNGGSGGAG---- MUL_0212|M.ulcerans_Agy99 PGGLFGAGGLGGAGGF----------------GGSGGGAGGQGGAGGLLS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EIGSHNQANIGTSTS-----------------AGGSAAVGGNAGLAG--- MAV_4827|M.avium_104 DYLYVPVDPEPGDDE----------------LAYSAVGEEDAESPTVVIE Mflv_5091|M.gilvum_PYR-GCK VGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG------ Mvan_1264|M.vanbaalenii_PYR-1 IGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG------ MSMEG_0868|M.smegmatis_MC2_155 MGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGK TH_3810|M.thermoresistible__bu --------------VDVVGGNP---------------------------- Mb1360c|M.bovis_AF2122/97 --------PGFNGGAGGAGGRSGLFEVLAAGGAG---------------- Rv2741|M.tuberculosis_H37Rv --------AALGGGAQAAGG------------------------------ MMAR_4362|M.marinum_M ---------GAGG-FLGSGG---------KGG-V---------------- MUL_0212|M.ulcerans_Agy99 ------GLVGAGGGHGGTGG---------YGGGA---------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------NAGLAGNAGLAGNAGLAGNAGLAGNAG---------------- MAV_4827|M.avium_104 KLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALE---------------- Mflv_5091|M.gilvum_PYR-GCK -------LQGGKGGDGGAGGKGGDADSMGS------------------AG Mvan_1264|M.vanbaalenii_PYR-1 -------LQGGQGGDGGTGGTGGDATSMGE------------------AG MSMEG_0868|M.smegmatis_MC2_155 ASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAAS TH_3810|M.thermoresistible__bu --------------DGGTPG------------------------------ Mb1360c|M.bovis_AF2122/97 -------GTGGLSVNGGTGGTGGTGG-GGG------------------LF Rv2741|M.tuberculosis_H37Rv --------------NGGAGGVG-------G------------------LF MMAR_4362|M.marinum_M -------GGVSAHQVGGTGGPGGTGG----------------------LL MUL_0212|M.ulcerans_Agy99 -------GGAGATGGGNTGGIGGDGGSAGM------------------LF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGNAGLAGNAG----------------LA MAV_4827|M.avium_104 --------IALAIGIRTTGTVALQPTPNQH-----------------LIV Mflv_5091|M.gilvum_PYR-GCK ATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD------ Mvan_1264|M.vanbaalenii_PYR-1 ATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN------ MSMEG_0868|M.smegmatis_MC2_155 ANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAY TH_3810|M.thermoresistible__bu AHGESHTPGVYTDRQ----------------------------------- Mb1360c|M.bovis_AF2122/97 SNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGAGGTGTG----- Rv2741|M.tuberculosis_H37Rv GAGGAGGAGGFSDTG----------------------------------- MMAR_4362|M.marinum_M GAGGAGGDGGQADDAIG--------------------------------- MUL_0212|M.ulcerans_Agy99 SNSGAGGAGGASELADG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAG------------------------------- MAV_4827|M.avium_104 PTEQAPAPPPVQASAPQPK------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------GGTGGAGGAGGTGG-TGGAGGTGG---------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------GGTGGNGGNGGTGG-TGGNGGTGG---------- MSMEG_0868|M.smegmatis_MC2_155 DPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQ TH_3810|M.thermoresistible__bu --------------------GEDGEDGTGTGIGGRGGNGG---------- Mb1360c|M.bovis_AF2122/97 ---------------NQLVGGEGGAGGAGGNAGILFGAGG---------- Rv2741|M.tuberculosis_H37Rv --------------------GTGGAGGAGG----LFGPG----------- MMAR_4362|M.marinum_M --------------------GTGGTGGSGG---TLYGSGG---------- MUL_0212|M.ulcerans_Agy99 --------------------GAGGAGGNGG---WLLSNGG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------NAGLAGNAGLAGNAGLAGNAG----------- MAV_4827|M.avium_104 ---------------ISVPEPVAAPKPLSPPVAAPLPAAP---------- Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 HSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGH TH_3810|M.thermoresistible__bu ------SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSH Mb1360c|M.bovis_AF2122/97 -------IGGTGGTGLGAPDP--GGTGGKGGVGGIGGAGA---LFGPGGA Rv2741|M.tuberculosis_H37Rv --------GGSGGVG---------GFGDTGGTGGDGGSGG---LFGVGGA MMAR_4362|M.marinum_M -------LGGNGGNGGHQGG-----------LGGAGGSGG---LFGDGGS MUL_0212|M.ulcerans_Agy99 -------VGGAGGAGADAVGPPFGIPAGSGSGGGAGGAGG--VFFGNGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAV MAV_4827|M.avium_104 -------PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV Mflv_5091|M.gilvum_PYR-GCK GGTGGKGG------TGGTGGAGGTG----GDGGTGGTGGTGGTG------ Mvan_1264|M.vanbaalenii_PYR-1 GGTGGKGG------TGGTGGDGGTG----GTGGTGGTGGTGGTG------ MSMEG_0868|M.smegmatis_MC2_155 GGDGGRGG------DGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDP TH_3810|M.thermoresistible__bu GGNGGHGG------RGGFLGIGGSG-------GWGGHGGNGGD------- Mb1360c|M.bovis_AF2122/97 GGTGGFGASSADQMAGGIGGSGGSGGA-AKLIGDGGAGGTGGD------- Rv2741|M.tuberculosis_H37Rv GGHGGFGS-----AAGGDGGAGGAGG---TVFGSGGAGGAGG-------- MMAR_4362|M.marinum_M GGDGGTGG-----TNGAAGGAGGRG---GLLYGSGGDGGDGGN------- MUL_0212|M.ulcerans_Agy99 GGAGGTGG-----DGGGTGGAGGAAGN-GVLIGNGGNGGIGGAA------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAAVGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVGGST------ MAV_4827|M.avium_104 SPPQLLAP-----PRLSVPQPVQPPVRVPQPPSPPQVGGTVPQS------ Mflv_5091|M.gilvum_PYR-GCK ---GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGG Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGG MSMEG_0868|M.smegmatis_MC2_155 SHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGG TH_3810|M.thermoresistible__bu ----TDADGGNGGDG---------------GNGGSAG------------- Mb1360c|M.bovis_AF2122/97 ---------SVRGAA---------------GSGGTGG-------TGGLIG Rv2741|M.tuberculosis_H37Rv ----------VATVA---------------GHGGHGGN------AGLLYG MMAR_4362|M.marinum_M ------GQPADGGAG---------------GAGGAG---------GLLG- MUL_0212|M.ulcerans_Agy99 ------GLWGTGGTG---------------GSGGSGGTGATGGFSGLLAS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------AVGGGAHTG--------------VGGGVSTGVGVGSHVGGGISE MAV_4827|M.avium_104 -------PPQHQTPP---------------GEGTPPK------------- Mflv_5091|M.gilvum_PYR-GCK QGG-----------------TGGTGGQGG--------LGGGGGTG----- Mvan_1264|M.vanbaalenii_PYR-1 QGG-----------------TGGTGGQGG--------LGGVGGTG----- MSMEG_0868|M.smegmatis_MC2_155 DGGEALIRATVIGSNASGTATGGDGGNGGT-------LGATNGTGGAATI TH_3810|M.thermoresistible__bu --------------------RGGTGGLRGV-------FGINGGNG----- Mb1360c|M.bovis_AF2122/97 --------------------DGGAGGAGGTGIE----FGSVGGAG----- Rv2741|M.tuberculosis_H37Rv --------------------TGGAGGAGG--------FGGFGGDG----- MMAR_4362|M.marinum_M --------------------AGGNGGDGGVG-------HDNGGAG----- MUL_0212|M.ulcerans_Agy99 GDG----------------GAGGAGGAGGAGGLLDGLVGAGGGDG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 S-------------------LGGSGSVGG---------STAVGGG----- MAV_4827|M.avium_104 --------------------PDGPGNYGGGHVP----TPGAGGSG----- Mflv_5091|M.gilvum_PYR-GCK ------------------GQGGTGGTGGQGGTGGTGGTGGTG-------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGQGGTGGTGGTGGTG-------- MSMEG_0868|M.smegmatis_MC2_155 VAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI TH_3810|M.thermoresistible__bu -------------------RAGLGGRGXXXXGGGVGAAVRSG-------- Mb1360c|M.bovis_AF2122/97 --------------------GAGGNAAGLSGAGGAGGAGGFG-------- Rv2741|M.tuberculosis_H37Rv --------------------GDGG-IGGLVGSGGAGGSGGTG-------- MMAR_4362|M.marinum_M --------------------GAGGRAGPLVGAGGNGGDGGAA-------- MUL_0212|M.ulcerans_Agy99 --------------------GAGGNAGTLFGSGGVGGDGGSG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------AHTGVGGGVSTGVGVGSHVGGG-------- MAV_4827|M.avium_104 --------------------GSGGGHVPTPGAGGSGGSGGGHVP------ Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGT Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGV MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGT TH_3810|M.thermoresistible__bu -------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------ Mb1360c|M.bovis_AF2122/97 -----ETAGD-GGAGGN--AGLLNGDGGAG---GAGGLGIAGDG------ Rv2741|M.tuberculosis_H37Rv -----TLSGGRGGAGGN--AGTFYGSGGAG---GAGGESDNGDG------ MMAR_4362|M.marinum_M -----GLHGGQGGGGGN--AGILLGNGGAGGTGGWGGFSVPGQG------ MUL_0212|M.ulcerans_Agy99 -----HGNGGDGGGGGN--AGLLFSDAGGG---GFGGFGLAGGG------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---ISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGG------ MAV_4827|M.avium_104 ----TPGTGGPGGTGGS--GGGHVPTPGAGTPGGSGGGHLPFPG------ Mflv_5091|M.gilvum_PYR-GCK AGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG----- Mvan_1264|M.vanbaalenii_PYR-1 AGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG----- MSMEG_0868|M.smegmatis_MC2_155 ASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV TH_3810|M.thermoresistible__bu ------------------IMPSSRAASARAG------------------- Mb1360c|M.bovis_AF2122/97 ---------------------GNGGKGGKAG------------------- Rv2741|M.tuberculosis_H37Rv ---------------------GNGGVGGKAG------------------- MMAR_4362|M.marinum_M ---------------------GTGGAGGHAG------------------- MUL_0212|M.ulcerans_Agy99 ---------------------GTGGSGGDAG------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------GISESLGGSGS------------------- MAV_4827|M.avium_104 ---------------------AGSTPGGSGG------------------- Mflv_5091|M.gilvum_PYR-GCK -AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGS Mvan_1264|M.vanbaalenii_PYR-1 -AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGS MSMEG_0868|M.smegmatis_MC2_155 MAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAI TH_3810|M.thermoresistible__bu --------AACASSTSRSRRSFCCSRA----------------------- Mb1360c|M.bovis_AF2122/97 --------MVGNGGDGGAGGASV--------------------------- Rv2741|M.tuberculosis_H37Rv --------LVGEGGNGGDGGATI--------------------------- MMAR_4362|M.marinum_M --------LIGNGGNGGAGGITS--------------------------- MUL_0212|M.ulcerans_Agy99 --------WLGSGGAGGAGGISVNGDAG------------------AGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------VGGSTAVGGGAHTSAINDALG--------------------- MAV_4827|M.avium_104 ----------GHLPTPGAG------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGG Mvan_1264|M.vanbaalenii_PYR-1 AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEA MSMEG_0868|M.smegmatis_MC2_155 SGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 -------------------------------------------------- Rv2741|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4362|M.marinum_M -------------------------------------------------- MUL_0212|M.ulcerans_Agy99 GGTSGQLLGDGGAGGAG----------------------------GEAEL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK SG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE------- Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE------- MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNG TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb1360c|M.bovis_AF2122/97 --VANGGVGGSGG-----------NATLIGNGGNGGNGGVGSA------- Rv2741|M.tuberculosis_H37Rv --AGKGGSGGNGG-----------NAWLTGQGGNGGNAAFGKAG------ MMAR_4362|M.marinum_M VAGGTGGDGGKGG-----------DAWVIGNGGNGGSGGTGTQ------- MUL_0212|M.ulcerans_Agy99 AAGGAGGSGGVGG-----------DAVLIGAGGNGGNGGPGTA------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSS------- MAV_4827|M.avium_104 --TPGGGLGGFGG-----------GHAPAPGGGLGGGGGHAPAP------ Mflv_5091|M.gilvum_PYR-GCK -GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 -GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ----------------------------------------------- Mb1360c|M.bovis_AF2122/97 -PGKGGAGGTAGLL-GLNGSPGLS----------------------- Rv2741|M.tuberculosis_H37Rv -TGSVGVGGAGGLLEGQNGENGLLPS--------------------- MMAR_4362|M.marinum_M -PGGPGVGGSGGSLIGQHGLNG------------------------- MUL_0212|M.ulcerans_Agy99 -KGDPGSGGAGG-LLGVDGLNGLS----------------------- MLBr_01183|M.leprae_Br4923 ----------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -MGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH----------- MAV_4827|M.avium_104 -GGGLGGFGGGHSGGGLGGLGGGHK----------------------