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MSFVIAAPEFLTAAAMDLASIGSTVSAASAAASAPTVAILAAGADEVSIAVAALFGMHGQAYQALSVQAS AFHQQFVQALTAGAYSYASAEAAAVTPLQQLVDVINAPFRSALGRPLIGNGANGKPGTGQDGGAGGLLYG SGGNGGSGLAGSGQKGGNGGAAGLFGNGGAGGAGASNQAGNGGAGGNGGAGGLIWGTAGTGGNGGFTTFL DAAGGAGGAGGAGGLFGAGGAGGVGGAALGGGAQAAGGNGGAGGVGGLFGAGGAGGAGGFSDTGGTGGAG GAGGLFGPGGGSGGVGGFGDTGGTGGDGGSGGLFGVGGAGGHGGFGSAAGGDGGAGGAGGTVFGSGGAGG AGGVATVAGHGGHGGNAGLLYGTGGAGGAGGFGGFGGDGGDGGIGGLVGSGGAGGSGGTGTLSGGRGGAG GNAGTFYGSGGAGGAGGESDNGDGGNGGVGGKAGLVGEGGNGGDGGATIAGKGGSGGNGGNAWLTGQGGN GGNAAFGKAGTGSVGVGGAGGLLEGQNGENGLLPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2741 | PE_PGRS47 | - | 100% (525) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1325c | PE_PGRS24 | e-172 | 56.46% (611) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0278c | PE_PGRS3 | e-160 | 60.07% (541) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2761 | PE_PGRS47 | 0.0 | 82.57% (522) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-100 | 44.59% (536) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 39.56% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-47 | 36.14% (415) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4362 | - | 1e-163 | 59.29% (538) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 4e-22 | 44.30% (158) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-78 | 44.66% (459) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-42 | 41.28% (298) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0212 | - | 1e-149 | 52.75% (582) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-98 | 43.51% (547) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2741|M.tuberculosis_H37Rv --------------------------------------------------
Mb2761|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4362|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv --------------------------------------------------
Mb2761|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4362|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv --------------------------------------------------
Mb2761|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4362|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv --------------------------------------------------
Mb2761|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4362|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2741|M.tuberculosis_H37Rv --------------------------------------------------
Mb2761|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4362|M.marinum_M --------------------------------------------------
MUL_0212|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------MSIIDFILNLFRDPVEAASYVADPEAALA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------MNIVLGV
Rv2741|M.tuberculosis_H37Rv ---------MSFVIAAP--EFLTAAAMDLASIGSTVSAASAAASAPTVAI
Mb2761|M.bovis_AF2122/97 ----MACLEVSDVICDRGTGVLTAAAMDLASIGSTVSAASAAASAPTVAI
MMAR_4362|M.marinum_M ---------MSFVIAEP--ELLAATATHLSSLRTTLVAANAAAAVPTTGL
MUL_0212|M.ulcerans_Agy99 ---------MSFVNVTP--EAVAAAASDLTGIGSVLGEANAVAARATTTV
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 NAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNY
MLBr_01183|M.leprae_Br4923 --------MPLFLNAEP--QALTAAANTLEGLSAATVASNAAAAQLTTEI
MAV_4827|M.avium_104 SMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILG
Rv2741|M.tuberculosis_H37Rv LAAGADEVSIAVAALFGMHGQAYQALSVQASAFHQQ----FVQALTAGAY
Mb2761|M.bovis_AF2122/97 LAAGADEVSIAVAALFGMHGQAYQALSVQASAFHQQ----FVQALTAGAY
MMAR_4362|M.marinum_M LAAADDEVSVAIAAGFRAYGQAYQALSTRAADVHAR----FVQALAAGAD
MUL_0212|M.ulcerans_Agy99 LAAGGDEVSAAIAALFSFHGQSYQTLGAQAEAFHAQ----FAQLMANGAG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 YAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP-IASGNQVMSPSGN
MLBr_01183|M.leprae_Br4923 APPAADDVSILLAHFFSGHGRQYQAHASQGATNHQD----LIQSLLTSSS
MAV_4827|M.avium_104 TREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAA
.
Rv2741|M.tuberculosis_H37Rv SYASAEAAAVTPLQQLVDVINAPFRSALGRPLIGN---------------
Mb2761|M.bovis_AF2122/97 SYASAEAAAVTPLQQLVDVINAPFRSALGRPLIGN---------------
MMAR_4362|M.marinum_M RYASAEAANAG--QQLLDIVNAPTQALIGRPLIGN---------------
MUL_0212|M.ulcerans_Agy99 TYASAEAANAAPFQGLLGAVNAPVQTLTGRPLIGN---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 VDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVG---------------
MLBr_01183|M.leprae_Br4923 AYAG--------------------TETANHDSL-----------------
MAV_4827|M.avium_104 ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDG---------------
.
Rv2741|M.tuberculosis_H37Rv -GANGKPGTGQDGGAGG---------------------------------
Mb2761|M.bovis_AF2122/97 -GANGKPGTGQDGGAGG---------------------------------
MMAR_4362|M.marinum_M -GTNGAPGTGQDGGPGG---------------------------------
MUL_0212|M.ulcerans_Agy99 -GANGAPGTGANGGAGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 -GSNSGPIASGQGSTAVN--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -SIPDVYKQQIRAESYG---------------------------------
Rv2741|M.tuberculosis_H37Rv ------------LLYGSGGNGGSGLAGS------------GQKGGNGGAA
Mb2761|M.bovis_AF2122/97 ------------LLYGSGGNGGSGLAGS------------GQKGGNGGAA
MMAR_4362|M.marinum_M ------------LLIGNGGSGGSGAAG--------------TNGGNGGAA
MUL_0212|M.ulcerans_Agy99 ------------WLIGNGGAGGSGAPG--------------LNGGAGGAA
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 -----------------GDVRDSNIIN-------------ADHGSNVGVD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------DAAGQLSAMVAG--------------LEKLESLPG
Rv2741|M.tuberculosis_H37Rv GLFGNGG--------------------AGGAGASN---------------
Mb2761|M.bovis_AF2122/97 GLFGNGG--------------------AGGAGASN---------------
MMAR_4362|M.marinum_M GLLGAGG--------------------AGGVGG-----------------
MUL_0212|M.ulcerans_Agy99 GLIGTGG--------------------AGGAGGSSSTV------------
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GLLLVGS----------------------GVDVAPLKQVLQTTTFLDVSV
Rv2741|M.tuberculosis_H37Rv ---------QAGNGGAG---------------------------------
Mb2761|M.bovis_AF2122/97 ---------QAGNGGAG---------------------------------
MMAR_4362|M.marinum_M ---------FGLPGGAG---------------------------------
MUL_0212|M.ulcerans_Agy99 ------NGGLGGTGGAGG--------------------------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ---------VDVVGGNP---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTN---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AEEPETALARGAALAAAN--------------------------------
Rv2741|M.tuberculosis_H37Rv --------GNGGAGGLIW---------------------------GTAGT
Mb2761|M.bovis_AF2122/97 --------GNGGAGGLIW---------------------------GTAGT
MMAR_4362|M.marinum_M --------GNGGAGGAG----------------------------GLFGN
MUL_0212|M.ulcerans_Agy99 -----WLLGNGGAGGAGGASAIPLGP-------DLIGKGGAGGPGGLFGA
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu ---------DGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199 -----TEIGSHNQANIGTSTS----------------------AGGSAAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----APLFASSTAALAYAQD-----------------------PGTGAV
Rv2741|M.tuberculosis_H37Rv GGNGGFTTFLDAAG------------------------------------
Mb2761|M.bovis_AF2122/97 GGNGGFTTFLDAAG------------------------------------
MMAR_4362|M.marinum_M GGNGGTG--GGSLD------------------------------------
MUL_0212|M.ulcerans_Agy99 GGLGGAGGFGGSGG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGNAGLAGNAGLAG------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DQYSLPDYLYVPVD------------------------------------
Rv2741|M.tuberculosis_H37Rv ---------------GAGGAGGAGG----LFGAGG---------------
Mb2761|M.bovis_AF2122/97 ---------------GAGGAGGAGG----LFGAGG---------------
MMAR_4362|M.marinum_M ---------------GNGGSGGAG-------GAGG--------------F
MUL_0212|M.ulcerans_Agy99 ---------------GAGGQGGAGGLLSGLVGAGGG-------------H
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 ----------NAGLAGNAGLAGNAGLAGNAGLAGN---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------PEPGDDELAYSAVGEEDAESP--------TVVIEK
Rv2741|M.tuberculosis_H37Rv --AGGVGGAALGGGAQAAGGNGGAGGVGG----LFGAGGAGGAGGFSDTG
Mb2761|M.bovis_AF2122/97 --AGGVGGAALGGGAQAAGGNGGAGGVGG----LFGAGGAGGAG------
MMAR_4362|M.marinum_M LGSGGKGG-VGGVSAHQVGGTGGPGGTGG----LLGAGGAGGDGGQADDA
MUL_0212|M.ulcerans_Agy99 GGTGGYGGGAGGAGATGGGNTGGIGGDGGSAGMLFSNSGAGGAGGASELA
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQP
Rv2741|M.tuberculosis_H37Rv GTGGAGGAGGLFGPGGGSGGVGGFGDTGGTG------------------G
Mb2761|M.bovis_AF2122/97 ----------------------GFGDTGGTG------------------G
MMAR_4362|M.marinum_M IGG----TGGTGGSGGTLYGSGGLGGNGGNGGHQGG-----------LGG
MUL_0212|M.ulcerans_Agy99 DGG----AGGAGGNGGWLLSNGGVGGAGGAGADAVGPPFGIPAGSGSGGG
Mflv_5091|M.gilvum_PYR-GCK GTGG---TGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGG---TGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGA---LGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu GRGG---FLGIGGSG-------GWGGHGGNGGD-----------TDADGG
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG-----NAGLAGNAGLAGNAGLAGNAGLAGNAAVAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPA
Rv2741|M.tuberculosis_H37Rv DGGSGG------------LFGVGGAGG-------HGGFGSAAG-------
Mb2761|M.bovis_AF2122/97 DGGSGG------------LFGVGGAGG-------HGGFGSAAG-------
MMAR_4362|M.marinum_M AGGSGG------------LFGDGGSGG-------DGGTGGTNG-------
MUL_0212|M.ulcerans_Agy99 AGGAGGV-----------FFGNGGAGG-------AGGTGGDGG-------
Mflv_5091|M.gilvum_PYR-GCK TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
TH_3810|M.thermoresistible__bu NGGDG---------------GNGGSAG-----------------------
MAB_4284c|M.abscessus_ATCC_199 NAAVAGN---------AAVAGNAAVGG--------VLNTGVSG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APPPAAP----------PLPEAPPIPAAPPVVPVPVVVPPVPVPVPVR--
Rv2741|M.tuberculosis_H37Rv ---------GDGGAGGAG---GTVFGSG----------------------
Mb2761|M.bovis_AF2122/97 ---------GDGGAGGAG---GTVFGSG----------------------
MMAR_4362|M.marinum_M ---------AAGGAGGRG---GLLYGSG----------------------
MUL_0212|M.ulcerans_Agy99 ---------GTGGAGGAAG-NGVLIGNG----------------------
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGG-LGGGGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGQGG-LGGVGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
TH_3810|M.thermoresistible__bu ----------RGGTGGLRGVFGINGGNG----------------------
MAB_4284c|M.abscessus_ATCC_199 ---------AIGGSSHVGGAINESLGGS----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------IPVPDPVSPPQLLAPPRLSVP----------------------
Rv2741|M.tuberculosis_H37Rv -GAGGAGGVATVAGHGGHGGN------------AGLLYG----TGGAGGA
Mb2761|M.bovis_AF2122/97 -GAGGAGGVATVAGHGGHGGN------------AGLLYG----TGGAGGA
MMAR_4362|M.marinum_M -GDGGDGGN-GQPADGGAGGAGGAG---------GLLG-----AGGNGGD
MUL_0212|M.ulcerans_Agy99 -GNGGIGGAAGLWGTGGTGGSGGSGGTGATGGFSGLLASGDGGAGGAGGA
Mflv_5091|M.gilvum_PYR-GCK -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
TH_3810|M.thermoresistible__bu --RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGT
MAB_4284c|M.abscessus_ATCC_199 -GSVGGSTAVGGGAHTGVGGGVSTG-------VGVGSHVGGGISESLGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QPVQPPVRVPQPPSPPQVGGTVPQSPP------QHQTPPGEGTPPKPDGP
Rv2741|M.tuberculosis_H37Rv GGFGG--------FGGDGGDGGIGG-LVGSGG------------------
Mb2761|M.bovis_AF2122/97 GGFGG--------FGGDGGDDGIGG-LVGSGG------------------
MMAR_4362|M.marinum_M GGVG-------HDNGGAGGAGGRAGPLVGAGG------------------
MUL_0212|M.ulcerans_Agy99 GGAGGLLDGLVGAGGGDGGAGGNAGTLFGSGG------------------
Mflv_5091|M.gilvum_PYR-GCK GGSGG-----TGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1 GGVGG-----TGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155 GGDGV-----VNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
TH_3810|M.thermoresistible__bu PSAGF-----GVPTTIQFPAGSCTSRAVSREG------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGG---STAVGGGAHTGVGGGVSTGVGVGS------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GNYGG----GHVPTPGAGGSGGSGGGHVPTPG------------------
Rv2741|M.tuberculosis_H37Rv ------AGGSGGTGTLSGGRGGAGGNAGTFYGS------GGAG---GAGG
Mb2761|M.bovis_AF2122/97 ------AGGSGGTGTLSGGRGGAGGNAGTFYGS------GGAG---GAGG
MMAR_4362|M.marinum_M ------NGGDGGAAGLHGGQGGGGGNAGILLGN------GGAGGTGGWGG
MUL_0212|M.ulcerans_Agy99 ------VGGDGGSGHGNGGDGGGGGNAGLLFSD------AGGG---GFGG
Mflv_5091|M.gilvum_PYR-GCK GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155 QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
TH_3810|M.thermoresistible__bu ------IMPSSRAASARAG---------------------------AACA
MAB_4284c|M.abscessus_ATCC_199 ----HVGGGISESLGGSGSVGGSTAVGGGAHTG------VGGGVNTGVGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------AGGSGGSGGGHVPTPGTGGPGGTGGSG--------------GGH
Rv2741|M.tuberculosis_H37Rv ESDNGDGGNGGVGGKAGLVG----------------------------EG
Mb2761|M.bovis_AF2122/97 ESDNGDGGNGGVGGKAGLVG----------------------------EG
MMAR_4362|M.marinum_M FSVPGQGGTGGAGGHAGLIG----------------------------NG
MUL_0212|M.ulcerans_Agy99 FGLAGGGGTGGSGGDAGWLG----------------------------SG
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
TH_3810|M.thermoresistible__bu SSTSRSRRSFCCSRA-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHVGGGISESLGGSGSVGG---------------------------STA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPTPGAGTPGGSGGGHLPFPG--------------------------AGS
Rv2741|M.tuberculosis_H37Rv GNGGDGGATI---------------------------------AGKGGSG
Mb2761|M.bovis_AF2122/97 GNGGDGGATI---------------------------------AGKGGSG
MMAR_4362|M.marinum_M GNGGAGGITS-------------------------------VAGGTGGDG
MUL_0212|M.ulcerans_Agy99 GAGGAGGISVNGDAGAGGAGGTSGQLLGDGGAGGAGGEAELAAGGAGGSG
Mflv_5091|M.gilvum_PYR-GCK SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINDALGGSG-----------------------SVGGSTAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TPGGSGGGHLPTPGAGTP------------------------GGGLGGFG
Rv2741|M.tuberculosis_H37Rv G-----------NGGNAWLTGQGGNGG------------NAAFGKAGTGS
Mb2761|M.bovis_AF2122/97 G-----------NGGNAWLTGQGGNGG------------NAAFGKAGTGS
MMAR_4362|M.marinum_M G-----------KGGDAWVIGNGGNGG------------SGGTGTQ-PGG
MUL_0212|M.ulcerans_Agy99 G-----------VGGDAVLIGAGGNGG------------NGGPGTA-KGD
Mflv_5091|M.gilvum_PYR-GCK G-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155 GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G------------GAHTSAINESMNSSINAS-------HSSSMNESFGSS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 G-------------GHAPAPGGGLGGG-------------GGHAPAPGGG
Rv2741|M.tuberculosis_H37Rv VGVGGAGGLLEGQNGENGLLPS-------------
Mb2761|M.bovis_AF2122/97 VGVGGAGGLLEGQNGENGLLPS-------------
MMAR_4362|M.marinum_M PGVGGSGGSLIGQHGLNG-----------------
MUL_0212|M.ulcerans_Agy99 PGSGGAGG-LLGVDGLNGLS---------------
Mflv_5091|M.gilvum_PYR-GCK SGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 SGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 MGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 -----------------------------------
MAV_4827|M.avium_104 LGGFGGGHSGGGLGGLGGGHK--------------