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APTHRIADWDPEDVSAWNAGNSVIARRNLIWANVTAHVGFSIWYLWSVMMLFMPQSVYGFSTGDKLLLGA TATLVGALVRIPYAMATTRFGGRSWAVFSSAVLFIPTIGAVVLLANPGLPLWPYLVCAALTGLGGGNYAA SLSHAEAFYPQRLKGFALGLTGGLSNLGSAAIQAVGLVVLATAGHEAPYLVCAVYLVLLAIAGLGAALFM DNLTHVIEVAHVRSVLKVPDSWGIALLYLCCSGSFLGFAFAFGQVLQHNFAAAGESHAQASLHAAEIAFI GPLLGSLSRIFGGRLGDRVGGGRVTFAALAAMIVAGGFLVAVSTHDDLTRGPNGQVTGTTMIGYICGFIA LFIFCGVGKGSVFKLIPSVFRERSRSLNLDGAQRRHWERVMSGALIGFAGSLGALGAMAINLVLRQSYVS TGTETPAFWIFLLCYIAAAALTWVRYARPRGVLLPAAAPLPAAAEVPVT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4265 | narK3_4 | - | 100% (470) | integral membrane nitrite extrusion protein NarK3_4 |
| M. marinum M | MMAR_2079 | narK3 | 0.0 | 73.70% (460) | integral membrane nitrite extrusion protein NarK3 |
| M. marinum M | MMAR_4257 | narK3_3 | 0.0 | 69.30% (469) | nitrite extrusion protein, NarK3_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0267c | narK3 | 1e-168 | 61.62% (469) | integral membrane nitrite extrusion protein NarK3 |
| M. gilvum PYR-GCK | Mflv_3015 | - | 1e-128 | 51.76% (454) | nitrite extrusion protein |
| M. tuberculosis H37Rv | Rv0261c | narK3 | 1e-168 | 61.62% (469) | integral membrane nitrite extrusion protein NarK3 |
| M. leprae Br4923 | MLBr_00844 | narK | 1e-148 | 57.05% (447) | putative nitrite extrusion protein |
| M. abscessus ATCC 19977 | MAB_3523c | - | 1e-131 | 53.03% (462) | integral membrane nitrite extrusion protein NarK3 |
| M. avium 104 | MAV_2079 | - | 0.0 | 72.61% (471) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_0433 | - | 1e-168 | 62.80% (457) | nitrite extrusion protein |
| M. thermoresistible (build 8) | TH_0644 | narK2 | 2e-10 | 26.18% (191) | POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 |
| M. ulcerans Agy99 | MUL_3265 | narK3 | 0.0 | 72.17% (460) | integral membrane nitrite extrusion protein NarK3 |
| M. vanbaalenii PYR-1 | Mvan_3492 | - | 4e-65 | 33.48% (454) | nitrite transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3015|M.gilvum_PYR-GCK ------------------------------MTWAFTGVMAKRTRDIDTWD
MAB_3523c|M.abscessus_ATCC_199 -----------------------------MANNTATAPIARRGRWIENWD
Mb0267c|M.bovis_AF2122/97 ---------------------------------------MGRSHQISDWD
Rv0261c|M.tuberculosis_H37Rv ---------------------------------------MGRSHQISDWD
MSMEG_0433|M.smegmatis_MC2_155 ------------------------------------MPTLLKPKRITNWD
MMAR_4265|M.marinum_M ---------------------------------------MAPTHRIADWD
MAV_2079|M.avium_104 ---------------------------------------MARTRRIAHWD
MUL_3265|M.ulcerans_Agy99 ---------------------------------------MGRSRHIAHWD
MLBr_00844|M.leprae_Br4923 MDQLVLLQAEESLYGPGRRSKTVPIDHRHSLKSSFFRLRLRRACRISHWD
Mvan_3492|M.vanbaalenii_PYR-1 ------------------MTVTDSESTGALATAAPAPERHRGKHWIDDWR
TH_0644|M.thermoresistible__bu --------------------------------------------------
Mflv_3015|M.gilvum_PYR-GCK PEDVQAWEGTGGKAPGKEIAKRNLIWSIVAEHVGFSVWSIWSVMVLFMPQ
MAB_3523c|M.abscessus_ATCC_199 PEDVVAWD-NG----GAKIARRNLIWSVVAEHVGFSVWSIWSVMVLFMPQ
Mb0267c|M.bovis_AF2122/97 PEDSVAWEAGN-----KFIARRNLIWSVAAEHVGFSVWSLWSVMVLFMPT
Rv0261c|M.tuberculosis_H37Rv PEDSVAWEAGN-----KFIARRNLIWSVAAEHVGFSVWSLWSVMVLFMPT
MSMEG_0433|M.smegmatis_MC2_155 PEDVAAWEAGN-----KYVARRNLIWSVVAEHIGFSIWSIWSVMVLFMPE
MMAR_4265|M.marinum_M PEDVSAWNAGN-----SVIARRNLIWANVTAHVGFSIWYLWSVMMLFMPQ
MAV_2079|M.avium_104 PEDLVAWEAGN-----KLIARRNLIWSIATMHVAFSIWYLWSVMVLFMPQ
MUL_3265|M.ulcerans_Agy99 PEDVQAWEAGN-----KAIARRNLVFSIATMHVGFSIWTLWSVMVLFMPQ
MLBr_00844|M.leprae_Br4923 PEDQAAWEAGN-----KTIARLNLLWSVLTVHLGYSVWTLWPVMELFMPK
Mvan_3492|M.vanbaalenii_PYR-1 PEDPEFWATTG-----KPVARRNLIFSIFAEHIGFSVWLLWSIVVVQMTA
TH_0644|M.thermoresistible__bu -----------------------------------MIGPLSTTYAVDIS-
: : . : :.
Mflv_3015|M.gilvum_PYR-GCK DVYG--------IDAAGKFYLVAVPTLVGAFMRIPYTIAPARFGGRNWTI
MAB_3523c|M.abscessus_ATCC_199 NVYH--------IDAAGKFFLVAMPTLVGAVLRLPYTFATAWFGGRNWTV
Mb0267c|M.bovis_AF2122/97 SVYG--------FSAGDKFLLGATATLVGACLRFPYTFATAKFGGRNWTI
Rv0261c|M.tuberculosis_H37Rv SVYG--------FSAGDKFLLGATATLVGACLRFPYTFATAKFGGRNWTI
MSMEG_0433|M.smegmatis_MC2_155 AVYG--------FSAGDKFLLGATATLVGSCLRIPYTLATATFGGRNWTV
MMAR_4265|M.marinum_M SVYG--------FSTGDKLLLGATATLVGALVRIPYAMATTRFGGRSWAV
MAV_2079|M.avium_104 ARYG--------FTTGDKLLVGATAALVGALVRIPYAMGTARLGGRNWAV
MUL_3265|M.ulcerans_Agy99 SVYG--------ISAANKLLLGATATLVGGCVRIPYVMATARFGGRNWAT
MLBr_00844|M.leprae_Br4923 DVYG--------FSAGDKFLLATTATLVGACLRVPYSLATALFGGRNWAI
Mvan_3492|M.vanbaalenii_PYR-1 GADGSPAASGFALTTTQALWLVAVPSGVGAFLRLPYTFAVPVFGGRNWTV
TH_0644|M.thermoresistible__bu ------------LSSAEASMLVATPILVGAVGRIVVGSLTDRYGGRAMFI
: : : : . **. *. ***
Mflv_3015|M.gilvum_PYR-GCK VSALLLLIPTVLAYYYMKNPAS-YTTYMVIAAFAGLGGGNFASSMTNINA
MAB_3523c|M.abscessus_ATCC_199 FSALVLAVPTALTLYFMAHPETSYTTFMIVAAVAGFGGGNFASSMTNINA
Mb0267c|M.bovis_AF2122/97 FSALVLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINA
Rv0261c|M.tuberculosis_H37Rv FSALVLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINA
MSMEG_0433|M.smegmatis_MC2_155 FSALVLLIPTVMTVVLMANPGLPLWPYLVCAALAGFGGGNFASSMTNINA
MMAR_4265|M.marinum_M FSSAVLFIPTIGAVVLLANPGLPLWPYLVCAALTGLGGGNYAASLSHAEA
MAV_2079|M.avium_104 LSSLVLLIPTLAAIVLLAHPGLPLWPYLVCAALTGLGGGNYAAALANVES
MUL_3265|M.ulcerans_Agy99 FSSLVLLVPTVGAIVLLANPGLPLWPYLVCAALSGVGGGNYSASLANVEA
MLBr_00844|M.leprae_Br4923 FSVMVLLIPTIATMVLLAHPGLPLWPYLACAALTGLGGGNFAASMTNANA
Mvan_3492|M.vanbaalenii_PYR-1 ISALLLLIPCLGLAWAVSNPDINFAVLLLIAATAGFGGGNFASSMANISF
TH_0644|M.thermoresistible__bu AITLASIVPVLAVG--AAGAAGSYPLLLVFGFFLGIAGTIFAVGIPFANN
:* . : . *..* :: .:. .
Mflv_3015|M.gilvum_PYR-GCK FYPQRLKGWALGLNAGGGNIGVPVIQLIGLMVIAAVGNTRPEIVCAIYLV
MAB_3523c|M.abscessus_ATCC_199 FYPQRFKGWALGLNAGGGNIGVPVIQVIGLLVIATVGNRSPHWVAAIYLV
Mb0267c|M.bovis_AF2122/97 FFPQRLKGAALALNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLV
Rv0261c|M.tuberculosis_H37Rv FFPQRLKGAALALNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLV
MSMEG_0433|M.smegmatis_MC2_155 FYPQRLKGWALGLNAGGGNIGVPMIQLVGLFVIATAGNRAPYWVCAVYLV
MMAR_4265|M.marinum_M FYPQRLKGFALGLTGGLSNLGSAAIQAVGLVVLATAGHEAPYLVCAVYLV
MAV_2079|M.avium_104 FFPQRRKGFALGLTGGVGNLGAAGIQAVGLVVLATAGNQAPYWVCAVYLV
MUL_3265|M.ulcerans_Agy99 FYPQRLKGVALGLTGGIGNLGVTAIQAVGLLVLATAGHEAPYWVCAVYLV
MLBr_00844|M.leprae_Br4923 FYPHRLKGAAFGLAGGAGNLGVSVIQVVGMLVIASVGDRKPYIVCGLYVV
Mvan_3492|M.vanbaalenii_PYR-1 FYPESEKGWALGLNAAGGNIGVAVAQKIIPVVVTLGAGVALSLAGLFYIP
TH_0644|M.thermoresistible__bu WYAPSRRGFATGVFG-MGMVGTALSAFFTPRFVESFG---LFTTHVIIAV
::. :* * .: . . :* . . .: . . .
Mflv_3015|M.gilvum_PYR-GCK AISGAAVGAALFMDNLRNQKSNFGALVEAMRFK----HSWVMSFLYIGTF
MAB_3523c|M.abscessus_ATCC_199 LIAFAAVGAALFMDNLADQKTDGRSLIDVMKYR----DSWIIAFLYIGTF
Mb0267c|M.bovis_AF2122/97 LLAVAGLGAALYMDNLTEYRIELNTMRAVVSEP----HTWVISLLYIGTF
Rv0261c|M.tuberculosis_H37Rv LLAVAGLGAALYMDNLTEYRIELNTMRAVVSEP----HTWVISLLYIGTF
MSMEG_0433|M.smegmatis_MC2_155 ALAVAGLGAALYMDNLEHHKIDLGAMKAILGER----DTWIISLLYIGTF
MMAR_4265|M.marinum_M LLAIAGLGAALFMDNLTHV-IEVAHVRSVLKVP----DSWGIALLYLCCS
MAV_2079|M.avium_104 LLALVGAGAALFMDNLDHS-VEVGHVRSVLTVP----DTWTISFLYMCAS
MUL_3265|M.ulcerans_Agy99 LIAIAGLGAALFMENLTHV-IEVGHVRSVLAVP----DTWSVSFLYMCAS
MLBr_00844|M.leprae_Br4923 LLIIAGIGAMLFMNDIEHHRIGVNTIRPVLFVVVSTRDSWVLALLYLASF
Mvan_3492|M.vanbaalenii_PYR-1 FTVAAAVCAFLFMNNLTEAKADVKPVWESLRHA----DTWIMSLLYIGTF
TH_0644|M.thermoresistible__bu ALGLTALLCLVAMHDSPDFTPNTERVLPKLKAAARLPVTWEMSILYAIVF
.. . : *.: . : : :* :::**
Mflv_3015|M.gilvum_PYR-GCK GSFIGFSFAFGQVLQINYLAG--------GDTPAQASLHAAQIAFLGPLL
MAB_3523c|M.abscessus_ATCC_199 GSFIGFSFAFGQVLQLNFLAGLAHSGVTPAQAAAQASLHAAQIAFIGPLL
Mb0267c|M.bovis_AF2122/97 GSFIGFSFAFGQVLQINFIAS--------GQSTAQASLHAAQIAFLGPLL
Rv0261c|M.tuberculosis_H37Rv GSFIGFSFAFGQVLQINFIAS--------GQSTAQASLHAAQIAFLGPLL
MSMEG_0433|M.smegmatis_MC2_155 GSFIGFAFAFGQVLQINFISG--------GQTPAQASLHAAQIAFIGPLL
MMAR_4265|M.marinum_M GSFLGFAFAFGQVLQHNFAAA--------GESHAQASLHAAEIAFIGPLL
MAV_2079|M.avium_104 GSFIGFAFAFGQVIAHNLIAG--------GQTHGQAALHAAEIAFAGPLL
MUL_3265|M.ulcerans_Agy99 GSFIGFAFVFGQVLQFNLLAG--------GQSTAQASLHAAEIAFVGPLL
MLBr_00844|M.leprae_Br4923 GSFIGFSFAFGQVLETNFVAG--------GQSTAQAALHAAELAFIGPTL
Mvan_3492|M.vanbaalenii_PYR-1 GSFIGYSAAFPTLLKAVFDRG----------------DIALMWAFLGAGI
TH_0644|M.thermoresistible__bu GGFVAFSNYLPTYXPSSPACT----------------------------I
*.*:.:: : :
Mflv_3015|M.gilvum_PYR-GCK GSISRPFGGKLADRVGGGRITLYVFVAMIFAAGVLVATGVMDDAA---AG
MAB_3523c|M.abscessus_ATCC_199 GSLARPFGGWLSDRTGGGKISLYAFIAMIFGAGILVAAGTISDRG---AG
Mb0267c|M.bovis_AF2122/97 GSLSRIYGGKLADRIGGGRVTLAAFCAMLLATGILISASTFGDHL---AG
Rv0261c|M.tuberculosis_H37Rv GSLSRIYGGKLADRIGGGRVTLAAFCAMLLATGILISASTFGDHL---AG
MSMEG_0433|M.smegmatis_MC2_155 GSLSRVYGGKLADRIGGGRVTLAVFAGMILGAGLLVAVSTVSDGS---SE
MMAR_4265|M.marinum_M GSLSRIFGGRLGDRVGGGRVTFAALAAMIVAGGFLVAVSTHDDLTRGPNG
MAV_2079|M.avium_104 GSMARVVGGKLGDRFDGGRVTLTVLAAMIVAGGFLVAVSTHDDLTRPSGA
MUL_3265|M.ulcerans_Agy99 GSLARIVGGKLGDRFGGGRVTLGVFVAMILSAALLVAVNTHADLNHGAGG
MLBr_00844|M.leprae_Br4923 AAVARFWGGRLADRLGGSRVTLVVFGAMVFAAGLLGVLGIIEGSR---VC
Mvan_3492|M.vanbaalenii_PYR-1 GSVARPLGGKLSDRVGGARITAVSFAMLAIGAAGALWS------------
TH_0644|M.thermoresistible__bu TTCTSTPPPRHSTRFG----------------------------------
: : . * .
Mflv_3015|M.gilvum_PYR-GCK APTSAQMIGYVAGFILLFILSGLGNGSTYKMIPSIFEAKAQGRDDLDKEG
MAB_3523c|M.abscessus_ATCC_199 APSGSIMTAYVIGFIILFVVSGIGNGSVYKMIPSVFAAKARSAG-LDET-
Mb0267c|M.bovis_AF2122/97 PMPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQ-ISEAE
Rv0261c|M.tuberculosis_H37Rv PMPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQ-ISEAE
MSMEG_0433|M.smegmatis_MC2_155 AATGLMMSGYVVGFIALFLLSGIGNGSVYKMIPSIFEARSHSLD-VSEDE
MMAR_4265|M.marinum_M QVTGTTMIGYICGFIALFIFCGVGKGSVFKLIPSVFRERSRSLN-LDGAQ
MAV_2079|M.avium_104 PVSLYTTAGYIAGFIALFICCGVGKGSVFKLIPSVFAQRSRALE-LGDTE
MUL_3265|M.ulcerans_Agy99 RMTAATLIGYVSGFIALFIFCGMGKGTVFELIPSIFAERSQHLD-ISDMQ
MLBr_00844|M.leprae_Br4923 PIRGVMMASYFAGFITLFILSGLGNGSVYKMIPTIFEACSHSLG-INDDE
Mvan_3492|M.vanbaalenii_PYR-1 -VQAKNMPVFFIAFMFLFVATGIGNGSTYRMISKIFRVKGEDAG--GDPL
TH_0644|M.thermoresistible__bu --------------------SGPGRSGPAGSWPMCSPPRNPVTT--AGSG
* *.. .
Mflv_3015|M.gilvum_PYR-GCK KAAWSRAMSGALIGFAGAVGALGGVFINVVLRASYVGDAKSATAAFWVFL
MAB_3523c|M.abscessus_ATCC_199 ---WSRTMSGALIGVAGAIGALGGVAINLVLRASYLSAAKSATMAFWVFL
Mb0267c|M.bovis_AF2122/97 RRQWSRSMSGALIGLAGAVGALGGVGVNLALRESYLTSG-TATSAFWAFG
Rv0261c|M.tuberculosis_H37Rv RRQWSRSMSGALIGLAGAVGALGGVGVNLALRESYLTSG-TATSAFWAFG
MSMEG_0433|M.smegmatis_MC2_155 RRHWSRSMSGALIGFAGAVGALGGVGINMALRQSYLSSG-SATTAFWTFL
MMAR_4265|M.marinum_M RRHWERVMSGALIGFAGSLGALGAMAINLVLRQSYVSTG-TETPAFWIFL
MAV_2079|M.avium_104 RRHWERARSAALIGFAGSFGALGGVVINLALRQSYASTG-SSTPAFGAFM
MUL_3265|M.ulcerans_Agy99 RRQWARIVSGALIGFAGSVGALGGVGINLALRQSYVHSG-TETPAFWAFL
MLBr_00844|M.leprae_Br4923 CRDWSRVISGVVIGFVAEVGALGGVGIDLALRESYLNTG-GVTAAFWIFM
Mvan_3492|M.vanbaalenii_PYR-1 TMLHMRRQAAGALGIISSVGAFGGFIVPLAYAWSKSQFG-NIQPALQFYV
TH_0644|M.thermoresistible__bu RSAITRRSRGHWIGVRSTR------------SHPMCRCGCSTAAACCGR-
* . :*. . . . *
Mflv_3015|M.gilvum_PYR-GCK AFYVVCAFVTWFVFLRLQEHRAHSGEHIGRTSAPVPVG-----
MAB_3523c|M.abscessus_ATCC_199 VFYVICAAVTWYAYVRRPMTVSVP--AISSSKNEVAV------
Mb0267c|M.bovis_AF2122/97 VFYLVASVLTWAIYVRRGLKSAGELVPATTAPAGLAYV-----
Rv0261c|M.tuberculosis_H37Rv VFYLVASVLTWAIYVRRGLKSAGELVPATTAPAGLAYV-----
MSMEG_0433|M.smegmatis_MC2_155 AFYVLASVVTWFCYVRR---PAAMPVTGTERHAPAIAG-----
MMAR_4265|M.marinum_M LCYIAAAALTWVRYAR-PRG-VLLPAAAP-LPAAAEVPVT---
MAV_2079|M.avium_104 LCYVAAAALTWARYVR-PRR-APEPRTAPDWQPMAEQPVSS--
MUL_3265|M.ulcerans_Agy99 VCYLCAAALTWARYVR-PRSPVASAPRKPNEDPQLSGAAA---
MLBr_00844|M.leprae_Br4923 LCYAAAGVLTWKMYVCRPLPGNLHDEAANAFAASVGASRTHRG
Mvan_3492|M.vanbaalenii_PYR-1 GFFIVLLGVTWFFYMR-----------KGTRMAQAGV------
TH_0644|M.thermoresistible__bu -------------------------------------------