For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PTLLKPKRITNWDPEDVAAWEAGNKYVARRNLIWSVVAEHIGFSIWSIWSVMVLFMPEAVYGFSAGDKFL LGATATLVGSCLRIPYTLATATFGGRNWTVFSALVLLIPTVMTVVLMANPGLPLWPYLVCAALAGFGGGN FASSMTNINAFYPQRLKGWALGLNAGGGNIGVPMIQLVGLFVIATAGNRAPYWVCAVYLVALAVAGLGAA LYMDNLEHHKIDLGAMKAILGERDTWIISLLYIGTFGSFIGFAFAFGQVLQINFISGGQTPAQASLHAAQ IAFIGPLLGSLSRVYGGKLADRIGGGRVTLAVFAGMILGAGLLVAVSTVSDGSSEAATGLMMSGYVVGFI ALFLLSGIGNGSVYKMIPSIFEARSHSLDVSEDERRHWSRSMSGALIGFAGAVGALGGVGINMALRQSYL SSGSATTAFWTFLAFYVLASVVTWFCYVRRPAAMPVTGTERHAPAIAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0433 | - | - | 100% (469) | nitrite extrusion protein |
| M. smegmatis MC2 155 | MSMEG_5141 | - | 6e-13 | 26.07% (349) | nitrate/nitrite transporter protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0267c | narK3 | 0.0 | 76.98% (443) | integral membrane nitrite extrusion protein NarK3 |
| M. gilvum PYR-GCK | Mflv_3015 | - | 1e-169 | 64.82% (452) | nitrite extrusion protein |
| M. tuberculosis H37Rv | Rv0261c | narK3 | 0.0 | 76.98% (443) | integral membrane nitrite extrusion protein NarK3 |
| M. leprae Br4923 | MLBr_00844 | narK | 1e-171 | 61.38% (448) | putative nitrite extrusion protein |
| M. abscessus ATCC 19977 | MAB_3523c | - | 1e-172 | 64.09% (465) | integral membrane nitrite extrusion protein NarK3 |
| M. marinum M | MMAR_0521 | narK3_2 | 1e-178 | 65.71% (452) | integral membrane nitrite extrusion protein NarK3_2 |
| M. avium 104 | MAV_4899 | - | 1e-178 | 65.40% (448) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_0644 | narK2 | 7e-07 | 27.23% (191) | POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 |
| M. ulcerans Agy99 | MUL_3265 | narK3 | 1e-174 | 64.96% (448) | integral membrane nitrite extrusion protein NarK3 |
| M. vanbaalenii PYR-1 | Mvan_3492 | - | 1e-88 | 41.39% (459) | nitrite transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3015|M.gilvum_PYR-GCK ------------------------------MTWAFTGVMAKRTRDIDTWD
MAB_3523c|M.abscessus_ATCC_199 -----------------------------MANNTATAPIARRGRWIENWD
Mb0267c|M.bovis_AF2122/97 ---------------------------------------MGRSHQISDWD
Rv0261c|M.tuberculosis_H37Rv ---------------------------------------MGRSHQISDWD
MSMEG_0433|M.smegmatis_MC2_155 ------------------------------------MPTLLKPKRITNWD
MLBr_00844|M.leprae_Br4923 MDQLVLLQAEESLYGPGRRSKTVPIDHRHSLKSSFFRLRLRRACRISHWD
MMAR_0521|M.marinum_M ---------------------------------------MNRNHRIEHWD
MAV_4899|M.avium_104 ---------------------------------------MGRDHRITDWN
MUL_3265|M.ulcerans_Agy99 ---------------------------------------MGRSRHIAHWD
Mvan_3492|M.vanbaalenii_PYR-1 ------------------MTVTDSESTGALATAAPAPERHRGKHWIDDWR
TH_0644|M.thermoresistible__bu --------------------------------------------------
Mflv_3015|M.gilvum_PYR-GCK PEDVQAWEGTGGKAPGKEIAKRNLIWSIVAEHVGFSVWSIWSVMVLFMPQ
MAB_3523c|M.abscessus_ATCC_199 PEDVVAWD-NG----GAKIARRNLIWSVVAEHVGFSVWSIWSVMVLFMPQ
Mb0267c|M.bovis_AF2122/97 PEDSVAWEAGN-----KFIARRNLIWSVAAEHVGFSVWSLWSVMVLFMPT
Rv0261c|M.tuberculosis_H37Rv PEDSVAWEAGN-----KFIARRNLIWSVAAEHVGFSVWSLWSVMVLFMPT
MSMEG_0433|M.smegmatis_MC2_155 PEDVAAWEAGN-----KYVARRNLIWSVVAEHIGFSIWSIWSVMVLFMPE
MLBr_00844|M.leprae_Br4923 PEDQAAWEAGN-----KTIARLNLLWSVLTVHLGYSVWTLWPVMELFMPK
MMAR_0521|M.marinum_M PEDAQAWEASN-----HAVARRNLLWITACDHVAFGVWTLWPVLVLFMPY
MAV_4899|M.avium_104 PEDAAAWEAGN-----KRIARRNLLCTIAGDHVAFSIWTLWPVMALFMPA
MUL_3265|M.ulcerans_Agy99 PEDVQAWEAGN-----KAIARRNLVFSIATMHVGFSIWTLWSVMVLFMPQ
Mvan_3492|M.vanbaalenii_PYR-1 PEDPEFWATTG-----KPVARRNLIFSIFAEHIGFSVWLLWSIVVVQMTA
TH_0644|M.thermoresistible__bu --------------------------------------MIGPLSTTYAVD
: .:
Mflv_3015|M.gilvum_PYR-GCK DVYGIDAAG--------KFYLVAVPTLVGAFMRIPYTIAPARFGGRNWTI
MAB_3523c|M.abscessus_ATCC_199 NVYHIDAAG--------KFFLVAMPTLVGAVLRLPYTFATAWFGGRNWTV
Mb0267c|M.bovis_AF2122/97 SVYGFSAGD--------KFLLGATATLVGACLRFPYTFATAKFGGRNWTI
Rv0261c|M.tuberculosis_H37Rv SVYGFSAGD--------KFLLGATATLVGACLRFPYTFATAKFGGRNWTI
MSMEG_0433|M.smegmatis_MC2_155 AVYGFSAGD--------KFLLGATATLVGSCLRIPYTLATATFGGRNWTV
MLBr_00844|M.leprae_Br4923 DVYGFSAGD--------KFLLATTATLVGACLRVPYSLATALFGGRNWAI
MMAR_0521|M.marinum_M DVYGFSAAD--------KFLLGATATFVAACLRIPYSLGIATFGGRNWTV
MAV_4899|M.avium_104 AVYGFSAGD--------KLLLGAVATLVGGCARIPYTLGIAAFGGRKWTT
MUL_3265|M.ulcerans_Agy99 SVYGISAAN--------KLLLGATATLVGGCVRIPYVMATARFGGRNWAT
Mvan_3492|M.vanbaalenii_PYR-1 GADGSPAASGFALTTTQALWLVAVPSGVGAFLRLPYTFAVPVFGGRNWTV
TH_0644|M.thermoresistible__bu ISLSSAEAS----------MLVATPILVGAVGRIVVGSLTDRYGGRAMFI
.. * : . *.. *. :***
Mflv_3015|M.gilvum_PYR-GCK VSALLLLIPTVLAYYYMKNPAS-YTTYMVIAAFAGLGGGNFASSMTNINA
MAB_3523c|M.abscessus_ATCC_199 FSALVLAVPTALTLYFMAHPETSYTTFMIVAAVAGFGGGNFASSMTNINA
Mb0267c|M.bovis_AF2122/97 FSALVLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINA
Rv0261c|M.tuberculosis_H37Rv FSALVLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINA
MSMEG_0433|M.smegmatis_MC2_155 FSALVLLIPTVMTVVLMANPGLPLWPYLVCAALAGFGGGNFASSMTNINA
MLBr_00844|M.leprae_Br4923 FSVMVLLIPTIATMVLLAHPGLPLWPYLACAALTGLGGGNFAASMTNANA
MMAR_0521|M.marinum_M FSIAVLAIPTIGTIWLLSHPGLPLWPYLACAALTGCGGANYAASMTNTNA
MAV_4899|M.avium_104 FSAVVLLIPTVGTIVLLANPGLPLWLFVLCAALTGLGGGNYAASLANVNA
MUL_3265|M.ulcerans_Agy99 FSSLVLLVPTVGAIVLLANPGLPLWPYLVCAALSGVGGGNYSASLANVEA
Mvan_3492|M.vanbaalenii_PYR-1 ISALLLLIPCLGLAWAVSNPDINFAVLLLIAATAGFGGGNFASSMANISF
TH_0644|M.thermoresistible__bu AITLASIVPVLAVG--AAGAAGSYPLLLVFGFFLGIAGTIFAVGIPFANN
:* . : . * .* :: .:. .
Mflv_3015|M.gilvum_PYR-GCK FYPQRLKGWALGLNAGGGNIGVPVIQLIGLMVIAAVGNTRPEIVCAIYLV
MAB_3523c|M.abscessus_ATCC_199 FYPQRFKGWALGLNAGGGNIGVPVIQVIGLLVIATVGNRSPHWVAAIYLV
Mb0267c|M.bovis_AF2122/97 FFPQRLKGAALALNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLV
Rv0261c|M.tuberculosis_H37Rv FFPQRLKGAALALNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLV
MSMEG_0433|M.smegmatis_MC2_155 FYPQRLKGWALGLNAGGGNIGVPMIQLVGLFVIATAGNRAPYWVCAVYLV
MLBr_00844|M.leprae_Br4923 FYPHRLKGAAFGLAGGAGNLGVSVIQVVGMLVIASVGDRKPYIVCGLYVV
MMAR_0521|M.marinum_M FYPHRRKGFALGFNAGAGNLGVPMIQLVGLLVIAIAGYHQPYWVCGLYLL
MAV_4899|M.avium_104 FYPQRLKGAAMAVNAGVANLGVAVIQLVGLLVLATAGHQAPYWVCAVYLV
MUL_3265|M.ulcerans_Agy99 FYPQRLKGVALGLTGGIGNLGVTAIQAVGLLVLATAGHEAPYWVCAVYLV
Mvan_3492|M.vanbaalenii_PYR-1 FYPESEKGWALGLNAAGGNIGVAVAQKIIPVVVTLGAGVALSLAGLFYIP
TH_0644|M.thermoresistible__bu WYAPSRRGFATGVFG-MGMVGTALSAFFTPRFVESFGLFTTHVIIAVALG
::. :* * .. . . :*.. . .: . . :
Mflv_3015|M.gilvum_PYR-GCK AISGAAVGAALFMDNLRNQKSNFGALV----EAMRFKHSWVMSFLYIGTF
MAB_3523c|M.abscessus_ATCC_199 LIAFAAVGAALFMDNLADQKTDGRSLI----DVMKYRDSWIIAFLYIGTF
Mb0267c|M.bovis_AF2122/97 LLAVAGLGAALYMDNLTEYRIELNTMR----AVVSEPHTWVISLLYIGTF
Rv0261c|M.tuberculosis_H37Rv LLAVAGLGAALYMDNLTEYRIELNTMR----AVVSEPHTWVISLLYIGTF
MSMEG_0433|M.smegmatis_MC2_155 ALAVAGLGAALYMDNLEHHKIDLGAMK----AILGERDTWIISLLYIGTF
MLBr_00844|M.leprae_Br4923 LLIIAGIGAMLFMNDIEHHRIGVNTIRPVLFVVVSTRDSWVLALLYLASF
MMAR_0521|M.marinum_M LLTVVAVGAARQMDNLAHATYDVGHLR----AILTQRDTWVLALLYLGTF
MAV_4899|M.avium_104 FLAAVAIAAAMFMDDINHG-TQLSTMR----SILFERDTHVISLLYIATF
MUL_3265|M.ulcerans_Agy99 LIAIAGLGAALFMENLTHV-IEVGHVR----SVLAVPDTWSVSFLYMCAS
Mvan_3492|M.vanbaalenii_PYR-1 FTVAAAVCAFLFMNNLTEAKADVKPVW----ESLRHADTWIMSLLYIGTF
TH_0644|M.thermoresistible__bu LTALLCLVAMHDSPDFTPNTERVLPKLK---AAARLPVTWEMSILYAIVF
: * :: : :::**
Mflv_3015|M.gilvum_PYR-GCK GSFIGFSFAFGQVLQINYLAG--------GDTPAQASLHAAQIAFLGPLL
MAB_3523c|M.abscessus_ATCC_199 GSFIGFSFAFGQVLQLNFLAGLAHSGVTPAQAAAQASLHAAQIAFIGPLL
Mb0267c|M.bovis_AF2122/97 GSFIGFSFAFGQVLQINFIAS--------GQSTAQASLHAAQIAFLGPLL
Rv0261c|M.tuberculosis_H37Rv GSFIGFSFAFGQVLQINFIAS--------GQSTAQASLHAAQIAFLGPLL
MSMEG_0433|M.smegmatis_MC2_155 GSFIGFAFAFGQVLQINFISG--------GQTPAQASLHAAQIAFIGPLL
MLBr_00844|M.leprae_Br4923 GSFIGFSFAFGQVLETNFVAG--------GQSTAQAALHAAELAFIGPTL
MMAR_0521|M.marinum_M GSWIGFSFAFGQVLQINFVGS--------GQSHAQAALHAAEFAFIGPAL
MAV_4899|M.avium_104 GSWIGFSFAFGQVMQVNFLEN--------GESAKHAALHAAQLAFIGPLL
MUL_3265|M.ulcerans_Agy99 GSFIGFAFVFGQVLQFNLLAG--------GQSTAQASLHAAEIAFVGPLL
Mvan_3492|M.vanbaalenii_PYR-1 GSFIGYSAAFPTLLKAVFDRG----------------DIALMWAFLGAGI
TH_0644|M.thermoresistible__bu GGFVAFSNYLPTYXPSSPACT----------------------------I
*.::.:: : :
Mflv_3015|M.gilvum_PYR-GCK GSISRPFGGKLADRVGGGRITLYVFVAMIF-AAGVLVATGVMDDAAAGAP
MAB_3523c|M.abscessus_ATCC_199 GSLARPFGGWLSDRTGGGKISLYAFIAMIF-GAGILVAAGTISDRGAGAP
Mb0267c|M.bovis_AF2122/97 GSLSRIYGGKLADRIGGGRVTLAAFCAMLL-ATGILISASTFGDHLAGP-
Rv0261c|M.tuberculosis_H37Rv GSLSRIYGGKLADRIGGGRVTLAAFCAMLL-ATGILISASTFGDHLAGP-
MSMEG_0433|M.smegmatis_MC2_155 GSLSRVYGGKLADRIGGGRVTLAVFAGMIL-GAGLLVAVSTVSDGSSEA-
MLBr_00844|M.leprae_Br4923 AAVARFWGGRLADRLGGSRVTLVVFGAMVF-AAGLLGVLGIIEGSRVCP-
MMAR_0521|M.marinum_M GSLARIYGGRLADRVGGSRVTLAVFITMAL-FTGLLVAISTHGDHTPGP-
MAV_4899|M.avium_104 GSVARIYGGRLADRVGGSRVTLGVLAAMTL-AAGLLVIVSTVDDQHAGA-
MUL_3265|M.ulcerans_Agy99 GSLARIVGGKLGDRFGGGRVTLGVFVAMIL-SAALLVAVNTHADLNHGAG
Mvan_3492|M.vanbaalenii_PYR-1 GSVARPLGGKLSDRVGGARITAVSFAMLAIGAAGALWSVQAKN-------
TH_0644|M.thermoresistible__bu TTCTSTPPPRHSTRFGSG--------------------------------
: : . * *..
Mflv_3015|M.gilvum_PYR-GCK ---TSAQMIGYVAGFILLFILSGLGNGSTYKMIPSIFEAKAQGRDDLDKE
MAB_3523c|M.abscessus_ATCC_199 ---SGSIMTAYVIGFIILFVVSGIGNGSVYKMIPSVFAAKARSAG-LDET
Mb0267c|M.bovis_AF2122/97 --MPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQ-ISEA
Rv0261c|M.tuberculosis_H37Rv --MPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQ-ISEA
MSMEG_0433|M.smegmatis_MC2_155 --ATGLMMSGYVVGFIALFLLSGIGNGSVYKMIPSIFEARSHSLD-VSED
MLBr_00844|M.leprae_Br4923 --IRGVMMASYFAGFITLFILSGLGNGSVYKMIPTIFEACSHSLG-INDD
MMAR_0521|M.marinum_M --ATVAMTAGYIGGFLALFALAGLGNGSVYKMIPSVFEALSHRNQ-ITEF
MAV_4899|M.avium_104 --HSVSMIG-YVVGFMVLFILSGMGNGSVFKLIPSVYEARSRGRD-TSED
MUL_3265|M.ulcerans_Agy99 GRMTAATLIGYVSGFIALFIFCGMGKGTVFELIPSIFAERSQHLD-ISDM
Mvan_3492|M.vanbaalenii_PYR-1 -------MPVFFIAFMFLFVATGIGNGSTYRMISKIFRVKGEDAG--GDP
TH_0644|M.thermoresistible__bu --------------------PGRSGPAGSWPMCSPPRNPVTTAGS-----
* . : : .
Mflv_3015|M.gilvum_PYR-GCK GKAAWSRAMSGALIGFAGAVGALGGVFINVVLRASYVGDAKSATAAFWVF
MAB_3523c|M.abscessus_ATCC_199 ----WSRTMSGALIGVAGAIGALGGVAINLVLRASYLSAAKSATMAFWVF
Mb0267c|M.bovis_AF2122/97 ERRQWSRSMSGALIGLAGAVGALGGVGVNLALRESYLTSG-TATSAFWAF
Rv0261c|M.tuberculosis_H37Rv ERRQWSRSMSGALIGLAGAVGALGGVGVNLALRESYLTSG-TATSAFWAF
MSMEG_0433|M.smegmatis_MC2_155 ERRHWSRSMSGALIGFAGAVGALGGVGINMALRQSYLSSG-SATTAFWTF
MLBr_00844|M.leprae_Br4923 ECRDWSRVISGVVIGFVAEVGALGGVGIDLALRESYLNTG-GVTAAFWIF
MMAR_0521|M.marinum_M ERRRWSQAMSGAVIGFVAAFGALGGVGINLALRQSYLSTG-TDTSAYWVF
MAV_4899|M.avium_104 ERRQWARAMAGSLIGICSAVGAFGGVAINLALRQSYLSTG-TETSAYWTF
MUL_3265|M.ulcerans_Agy99 QRRQWARIVSGALIGFAGSVGALGGVGINLALRQSYVHSG-TETPAFWAF
Mvan_3492|M.vanbaalenii_PYR-1 LTMLHMRRQAAGALGIISSVGAFGGFIVPLAYAWSKSQFG-NIQPALQFY
TH_0644|M.thermoresistible__bu GRSAITRRSRGHWIGVRSTR------------SHPMCRCGCSTAAACCGR
: . :*. . . . *
Mflv_3015|M.gilvum_PYR-GCK LAFYVVCAFVTWFVFLRLQEH-------RAHSGEHIGRTSAPVPVG
MAB_3523c|M.abscessus_ATCC_199 LVFYVICAAVTWYAYVRRPMT-------VSVP--AISSSKNEVAV-
Mb0267c|M.bovis_AF2122/97 GVFYLVASVLTWAIYVRRGLK-------SAGELVPATTAPAGLAYV
Rv0261c|M.tuberculosis_H37Rv GVFYLVASVLTWAIYVRRGLK-------SAGELVPATTAPAGLAYV
MSMEG_0433|M.smegmatis_MC2_155 LAFYVLASVVTWFCYVRR----------PAAMPVTGTERHAPAIAG
MLBr_00844|M.leprae_Br4923 MLCYAAAGVLTWKMYVCRPLPGNLHDEAANAFAASVGASRTHRG--
MMAR_0521|M.marinum_M LLFYVGAALLTWSRYGRRAVP-------VAGTAGTASGSRLARV--
MAV_4899|M.avium_104 MASYVVAAIMTWLVYVRRPVT---------APGVSLPETQAARL--
MUL_3265|M.ulcerans_Agy99 LVCYLCAAALTWARYVRPRSP------VASAPRKPNEDPQLSGAAA
Mvan_3492|M.vanbaalenii_PYR-1 VGFFIVLLGVTWFFYMRKGTR----------------MAQAGV---
TH_0644|M.thermoresistible__bu ----------------------------------------------