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MSYLVAVPEMLASAALDLDNIGSTITAANAAAAAPTTAVLAAGADEISAAVAALFTGHAQAYQWLGAQAG AFHSQFIQALTGSGIAYAGAEAANASPLQTAAQELLAVINTPTQTLLGRPLIGNGADGAPGQAGGDGGLL YGNGGNGGTSTTAGVAGGDGGAAGLIGNGGAGGGGGAGALGGNGGAGGWLFGQGGAGGNGGTATLAGGAG GAGGVGGSAGLWGTGGAGGNGGFGALNLAGDGGAGAGGGDGGRGGWLYGNGGVGGTGGTGGIGLQGASGG DGGAGGGTGLWGTGGVGGNGGTGGIGLDGVAGHIGGGNAGNAGNGGTGGSGGLLLGNGGDGGHGGTGGGG GRGINGADGGHGGDGGTGGAAGSAGLLFGDGGTGGHGGAGFGGGNGSDSPQGGQGGNAGVAGNGGAGGSA AMLFGNGGAGGNGGSGGDGGHGGNSTVSVPGGIGGDAGAGGTGGSAGKSGLLFGAGGAGGQGGGGGTGGD GGNNIIGANVGGDGGAGGAGGLGGNGTDGGWLSGNGGDGGAGGQGGDGGHGGSPGGFDGKSGVGGDGGDG GNARIIGNGGNGGNGGAGSTDGEGGQGGAAGLLFGQPGSMGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4223 | - | - | 100% (602) | PE-PGRS family protein |
| M. marinum M | MMAR_4224 | - | 0.0 | 64.65% (611) | PE-PGRS family protein |
| M. marinum M | MMAR_0837 | - | 0.0 | 56.52% (621) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 56.23% (674) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-118 | 45.37% (615) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 56.13% (677) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-13 | 39.58% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-50 | 34.65% (456) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-22 | 39.88% (173) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-105 | 41.27% (693) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-48 | 41.09% (348) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-170 | 53.72% (646) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-119 | 46.84% (570) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4223|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4223|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4223|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4223|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4223|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 -------------------------MSFVIAAPEALVAVASDLAGIGSAL
Rv1091|M.tuberculosis_H37Rv -------------------------MSFVIAAPEALVAVASDLAGIGSAL
MMAR_4223|M.marinum_M -------------------------MSYLVAVPEMLASAALDLDNIGSTI
MUL_3292|M.ulcerans_Agy99 -------------------------MSYVIAAPEMLAGAATDLAGIGAAL
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 -----------------------------MSIIDFILNLFRDPVEAASYV
MLBr_01183|M.leprae_Br4923 ------------------------MPLFLNAEPQALTAAANTLEGLSAAT
MAV_4827|M.avium_104 ---------------------MNIVLGVSMAPSSIQMVVLEGEYADGATV
Mb1121|M.bovis_AF2122/97 AEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQ
Rv1091|M.tuberculosis_H37Rv AEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQ
MMAR_4223|M.marinum_M TAANAAAAAPTTAVLAAGADEISAAVAALFTGHAQAYQWLGAQAGAFHSQ
MUL_3292|M.ulcerans_Agy99 QSANGAAAAPITGVLAAGADEISAAVAALFSGHALDYQALSTQMAGFHQQ
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 ADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHD
MLBr_01183|M.leprae_Br4923 VASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQD
MAV_4827|M.avium_104 EEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ
. :
Mb1121|M.bovis_AF2122/97 FVQALTGGGGAYAAAEAANVSAAQSTDQRLLDLIN--------------G
Rv1091|M.tuberculosis_H37Rv FVQALTGGGGAYAAAEAANVSAAQSTDQRLLDLIN--------------G
MMAR_4223|M.marinum_M FIQALTGSGIAYAGAEAANASPLQTAAQELLAVIN--------------T
MUL_3292|M.ulcerans_Agy99 FVTALNSAGASYAAAEAASANPLQAVEQQLLGVIN--------------A
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 LSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHN--------------D
MLBr_01183|M.leprae_Br4923 LIQSL------------------LTSSSAYAGTET---------------
MAV_4827|M.avium_104 LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGG-------------A
Mb1121|M.bovis_AF2122/97 PTQALLGRPLIGDGANG-----GPGQDGGPGGLLYG--------------
Rv1091|M.tuberculosis_H37Rv PTQALLGRPLIGDGANG-----GPGQDGGPGGLLYG--------------
MMAR_4223|M.marinum_M PTQTLLGRPLIGNGADG-----APGQAGGDGGLLYG--------------
MUL_3292|M.ulcerans_Agy99 PTQALLGRPLIGDGTAG-----APGQNGGDGGLLWG--------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG--------------
MLBr_01183|M.leprae_Br4923 ANHDSL--------------------------------------------
MAV_4827|M.avium_104 MGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIR-------------
Mb1121|M.bovis_AF2122/97 ----------------NGGNGGTSTTAG-------------VAGGNGGAA
Rv1091|M.tuberculosis_H37Rv ----------------NGGNGGTSTTAG-------------VAGGNGGAA
MMAR_4223|M.marinum_M ----------------NGGNGGTSTTAG-------------VAGGDGGAA
MUL_3292|M.ulcerans_Agy99 ----------------NGGAGGVGTAAH-------------PTGGSGGSA
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 --------------DLQFGNRDTTAIGDG----------AVAVGGSNSGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------AESYGDAAGQLS------------AMVAGLEKLE
Mb1121|M.bovis_AF2122/97 GLIGNGGAGGGG-------------GAGAAGGNGGAGGWLYGNGGAGGA-
Rv1091|M.tuberculosis_H37Rv GLIGNGGAGGGG-------------GAGAAGGNGGAGGWLYGNGGAGGA-
MMAR_4223|M.marinum_M GLIGNGGAGGGG-------------GAGALGGNGGAGGWLFGQGGAGGN-
MUL_3292|M.ulcerans_Agy99 GLIGTGGAGGAGY------------GPAAQTGATGGSGGVGGTGGSGLD-
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNG----------------DVRDSNIINADHGSNVGVDQSQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SLPGGLLLVGSG------------VDVAPLKQVLQTTTFLDVSVAEEPET
Mb1121|M.bovis_AF2122/97 ---GGTSVIPGVAGGNGGAGGSAGLWGTG---------------------
Rv1091|M.tuberculosis_H37Rv ---GGTSVIPGVAGGNGGAGGSAGLWGTG---------------------
MMAR_4223|M.marinum_M ---GGTATLAGGAGGAGGVGGSAGLWGTG---------------------
MUL_3292|M.ulcerans_Agy99 ---GPDSGAAGGAGGSGGSGGAARLFGNG---------------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ---------VDVVGGNP---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TRVGGDYTNVSGHGSADIDKSVTVVDDHS---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ALARGAALAAANAPLFASSTAALAYAQDP---------------------
Mb1121|M.bovis_AF2122/97 -----GAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKG
Rv1091|M.tuberculosis_H37Rv -----GAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKG
MMAR_4223|M.marinum_M -----GAGGNGGFG---ALNLAG---------------------------
MUL_3292|M.ulcerans_Agy99 -----GAGGSGGKGGNGGSAIETG--------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE-------------------------
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATG------------NTAIG
TH_3810|M.thermoresistible__bu ---------DGGTPG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 --QRNTTNINDSFNTDRSTNIGSGN-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----GTGAVDQYSLPDYLYVPVDP-------------------------
Mb1121|M.bovis_AF2122/97 GAGGAAFSINFTAGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGG
Rv1091|M.tuberculosis_H37Rv GAGGAAFSINFTAGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGG
MMAR_4223|M.marinum_M --------------DGGAG----------------------------AG-
MUL_3292|M.ulcerans_Agy99 -------------NDGAAG-------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGA
Mvan_1264|M.vanbaalenii_PYR-1 -----AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGG
TH_3810|M.thermoresistible__bu -------AHGESHTPGVYTDRQ----------------------------
MAB_4284c|M.abscessus_ATCC_199 -------TTNTEIGSHNQANIGTSTS------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------EPGDDELAYSAVG------------------------
Mb1121|M.bovis_AF2122/97 ST------------------AGAGGNGGAGGGGGTGGLLFGNGGAGGHGA
Rv1091|M.tuberculosis_H37Rv ST------------------AGAGGNGGAGGGGGTGGLLFGNGGAGGHGA
MMAR_4223|M.marinum_M -----------------------------GGDGGRGGWLYGNGGVG----
MUL_3292|M.ulcerans_Agy99 -------------------------------AGGHGGWLVGNGGIGGDG-
Mflv_5091|M.gilvum_PYR-GCK D----------------------GGTGGAGGAGGTGG-TGGAGGTGG---
Mvan_1264|M.vanbaalenii_PYR-1 N----------------------GGTGGNGGNGGTGG-TGGNGGTGG---
MSMEG_0868|M.smegmatis_MC2_155 NGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGAS
TH_3810|M.thermoresistible__bu ---------------------------GEDGEDGTGTGIGGRGGNGG---
MAB_4284c|M.abscessus_ATCC_199 -------------------------AGGSAAVGGNAGLAGNAGLAGNAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------EEDAESPTVVIEKLFLPEDS-
Mb1121|M.bovis_AF2122/97 A-AGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVGG-AG
Rv1091|M.tuberculosis_H37Rv A-AGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVGG-AG
MMAR_4223|M.marinum_M ----------------GTGGTGGIGLQGASGGDGGAGGGTGLWGTGG-VG
MUL_3292|M.ulcerans_Agy99 ----------------GSGGVGGDAGAYGPPANGGAGGHGGMGGVGGDAG
Mflv_5091|M.gilvum_PYR-GCK --------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTG
MSMEG_0868|M.smegmatis_MC2_155 VWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEG
TH_3810|M.thermoresistible__bu -------------SSSGTHPMAEDG--------EHVKALDGRPGLD---G
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------EPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTT
Mb1121|M.bovis_AF2122/97 GAGGDGGAGGAGGKGGSGLSGN-ANGGAG----GDSGRGGTGGAGGEGGA
Rv1091|M.tuberculosis_H37Rv GAGGDGGAGGAGGKGGSGLSGN-ANGGAG----GDSGRGGTGGAGGEGGA
MMAR_4223|M.marinum_M GNGGTGGIG------LDGVAGH-IGGGNA----GNAGNGGTGGSGG----
MUL_3292|M.ulcerans_Agy99 LLFGSGGAG--------GVGGNGAIGGTG----VMSGAGGAGGDGGNGG-
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG-----KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGG-----KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 GTGGHGGDGG-----RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGT
TH_3810|M.thermoresistible__bu GNGSHGGNGG-----HGGRGGFLGIGGSG-------GWGGHGGNGGD---
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGN------AGLAGNAGLAGNAG-LAGNAGLAGNAGLAGNAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTVALQPTPN------QHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAP
Mb1121|M.bovis_AF2122/97 --AGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGR----GGAG
Rv1091|M.tuberculosis_H37Rv --AGLLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGR----GGAG
MMAR_4223|M.marinum_M ----LLLGNGGDGGHGGTG------------------GGGGR----GING
MUL_3292|M.ulcerans_Agy99 --YAQLIGDGGGGGAGGAG-----------------YSASGL----PPAG
Mflv_5091|M.gilvum_PYR-GCK -------GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQG
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFG
MSMEG_0868|M.smegmatis_MC2_155 YVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRG
TH_3810|M.thermoresistible__bu --------TDADGGNGGDG---------------GNGGSAG---------
MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAG-------------LAGNAGLAGN----AGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 KPLSPPVAAPLPAAPPPAAP--------------PLPEAPPIPAAPPVVP
Mb1121|M.bovis_AF2122/97 GSGGSGG-----------------DGG-GGAAGPAGWLFGDG--------
Rv1091|M.tuberculosis_H37Rv GSGGSGG-----------------DGG-GGAAGPAGWLFGDG--------
MMAR_4223|M.marinum_M ADGGHGG-----------------DGGTGGAAGSAGLLFGDG--------
MUL_3292|M.ulcerans_Agy99 ----IGA-----------------PGGAGGAGGSGGWLVGNG--------
Mflv_5091|M.gilvum_PYR-GCK GQGGQGG-----------------TGGTGGQGG-LGGGGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 GQGGQGG-----------------TGGTGGQGG-LGGVGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 GKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAY
TH_3810|M.thermoresistible__bu ------------------------RGGTGGLRGVFGINGGNG--------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAG-----------------NAAVAGNAAVAGNAAVAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPVVVPP-----------------VPVPVPVRIPVPDPVSPP--------
Mb1121|M.bovis_AF2122/97 ------------------GAGGNGGAAAAGGAGGQAGGG----------G
Rv1091|M.tuberculosis_H37Rv ------------------GAGGNGGAAAAGGAGGQAGGG----------G
MMAR_4223|M.marinum_M ------------------GTGGHGGAGFGGGNGSDSP-------------
MUL_3292|M.ulcerans_Agy99 ------------------GAGGIGGIGASGSFGAPSG-------------
Mflv_5091|M.gilvum_PYR-GCK ---------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTG
MSMEG_0868|M.smegmatis_MC2_155 NVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAG
TH_3810|M.thermoresistible__bu ----------------RAGLGGRGXXXXGGGVGAAVRSG-----------
MAB_4284c|M.abscessus_ATCC_199 ----------------NAAVGGVLNTGVSGAIGGSSHVG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------QLLAPPRLSVPQPVQPPVRVP-----------
Mb1121|M.bovis_AF2122/97 GNGGNGGNGGNGGNGGNGATGGWLYGNGGAGGQGATAGAGGAGANGVSST
Rv1091|M.tuberculosis_H37Rv GNGGNGGNGGNGGNGGNGATGGWLYGNGGAGGQGATAGAGGAGANGVSST
MMAR_4223|M.marinum_M -QGGQGGNAGVAGNGGAGGSAAMLFGNGGAGGN-----------------
MUL_3292|M.ulcerans_Agy99 -QGGNGGIGGAAG----------LFGQGGAGGN-----------------
Mflv_5091|M.gilvum_PYR-GCK GAGGDGGLGGLGGFGGSGGTGG-QGGLGGPGGS-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GAGGDGGLGGLGGFGGVGGTGG-QGGQGGPGGS-----------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGIDGGLGGNGGDGVVNT-TANAANPGSA-----------------
TH_3810|M.thermoresistible__bu ----NGVFSGGGGTPSAGFGVP-TTIQFPAGSC-----------------
MAB_4284c|M.abscessus_ATCC_199 -GAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---QPPSPPQVGGTVPQSPPQHQTPPGEGTPPK-----------------
Mb1121|M.bovis_AF2122/97 NGG---GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGT
Rv1091|M.tuberculosis_H37Rv NGGGTGGNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGT
MMAR_4223|M.marinum_M -----------GGSGGDGGHGGNS--------------------------
MUL_3292|M.ulcerans_Agy99 -----------------GGQGGGD--------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGAGGAGG-----------------QAGTAGKGGLF
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGAGGAGG-----------------QAGVAGKGGLF
MSMEG_0868|M.smegmatis_MC2_155 -------------TGTATGGDGGK---------------ATGTASQGGNG
TH_3810|M.thermoresistible__bu -------------TSRAVSREG----------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------VGVGSHVGG----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------PDGPGNYGG----------------------------
Mb1121|M.bovis_AF2122/97 GFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNG
Rv1091|M.tuberculosis_H37Rv GFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNG
MMAR_4223|M.marinum_M -TVSVPGGIGGDAGAGGTGGSAGKSGLLFGAGGAGGQGG-----------
MUL_3292|M.ulcerans_Agy99 -------DFALSGGAGGAGGAGGHGGQLYGDGGGGGAGG------MGGSV
Mflv_5091|M.gilvum_PYR-GCK G----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG
Mvan_1264|M.vanbaalenii_PYR-1 G----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG
MSMEG_0868|M.smegmatis_MC2_155 GPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTG
TH_3810|M.thermoresistible__bu -----------IMPSSRAASARAG--------------------------
MAB_4284c|M.abscessus_ATCC_199 -------GISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------GHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGG-----------
Mb1121|M.bovis_AF2122/97 GAGNGGGTDGNGGNGGSGGGAGSGG--------------DGGGAGGNGAW
Rv1091|M.tuberculosis_H37Rv GAGNGGGTDGNGGNGGSGGGAGSGG--------------DGGGAGGNGAW
MMAR_4223|M.marinum_M ----GGGTGGDGGNNIIGANVG----------------------------
MUL_3292|M.ulcerans_Agy99 DIAESGVTGGRGGSGSVGGGAG----------------------------
Mflv_5091|M.gilvum_PYR-GCK -ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-
Mvan_1264|M.vanbaalenii_PYR-1 -ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-
MSMEG_0868|M.smegmatis_MC2_155 VATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAG
TH_3810|M.thermoresistible__bu -AACASSTSRSRRSFCCSRA------------------------------
MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVGGGAHTGVG-------------------GGVNT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GHVPTPGTGGPGGTGGSGGGHVPTP-------------------------
Mb1121|M.bovis_AF2122/97 LFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPGGV
Rv1091|M.tuberculosis_H37Rv LFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPGGV
MMAR_4223|M.marinum_M --GDGGAGGAGGLGGNGTDGGW---------LSGNGGDGGAGGQG-----
MUL_3292|M.ulcerans_Agy99 LWGAGGQGGDGAQGGDGGAGVDT--------TTGAGGDGGAGAGGGTSGF
Mflv_5091|M.gilvum_PYR-GCK NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGG
Mvan_1264|M.vanbaalenii_PYR-1 NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGSVG----------GSTAVGGGAHTSAINDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --GAGTPGGSGGGHLP---------------FPGAGSTPGGSGGGHLPTP
Mb1121|M.bovis_AF2122/97 LYGNGGAGGQGSSGG--IGGPGATGGAGGKGGDGGD-----AQLIGDGGN
Rv1091|M.tuberculosis_H37Rv LYGNGGAGGQGSSGG--IGGPGATGGAGGKGGDGGD-----AQLIGDGGN
MMAR_4223|M.marinum_M --GDGGHGG--SPGG--FDG---KSGVGGDGGDGGN-----ARIIGNGGN
MUL_3292|M.ulcerans_Agy99 LYGNGGAGGAGGHGG--GGP--GMGGDGGDGGDGGR-----AQLIGTGGN
Mflv_5091|M.gilvum_PYR-GCK AGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGG
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGS
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSS-------SMNESFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GAGTPG------------------GGLGGFGGGHAP-------APGGGLG
Mb1121|M.bovis_AF2122/97 GGNGGAGGTGGTPGPGGPGGSGGLGGLLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv GGNGGAGGTGGTPGPGGPGGSGGLGGLLFGQTGTAGVSP-
MMAR_4223|M.marinum_M GGNGGAGSTD------GEGGQGGAAGLLFGQPGSMGT---
MUL_3292|M.ulcerans_Agy99 GGAGGTAAPGG---TDGTAGAAGKGGVLFGTDGATG----
Mflv_5091|M.gilvum_PYR-GCK GGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 ----------------------------------------
MAV_4827|M.avium_104 GGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------