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M. marinum M MMAR_4149 (-)

annotation: PE-PGRS family protein
coordinates: 5109713 - 5111515
length: 600

SFVVVSPEVLAVAGRDLASIGSAISQANVAAAAPTMGALAAGADEVSAAVAAVFSGHAQAYQALGAQVAA
FHDQLVTALDAAAGKYASAEVANASPLQAVLDVVNAPAQALLGRPLIGNGDDGVAGTGQSGGDGGILYGN
GGDGGSGASGQIGGTGGSAGLIGAGGTGGAGGLGAAGGAGGNGGWLFGQGGAGGIGGSGAAGGAGGNGGW
LYGDGGAGGQGGAAAESINDGSPGQGGNGGSAYLFGNGGSGGQGGTGLAGADGVNYSNGTAGPGAWGNNV
TTSIGDANGGNGGSGADGGAGVTGGTGGVGGFANNEGSGDANGGFGGTGGNGGAPGASGGEGGTGGVAIA
SGGNAYGGSGGTGGNGATGASGGTGGTGGTGGDGGHGGLLIGNGGIGGIGGTGGVGGIGGTGGDGGTGGV
GGSALNTGSGVADANIGGDGGDAGTGGDGGTGGVGGVGGSGGAGGLLFGNGGDGGAGGDGGVGGTGGIGG
AGGNGGVGGDGSSSGTGAGGSGGDATDGGTGGDGGSGGGFGTGGAGGTGGWLIGHSGTNGIGGTGGAGGA
GAVGGDGGVGGDPGVGTTYNGISGHNGVQGGTGADGAAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4149--100% (600)PE-PGRS family protein
M. marinum MMMAR_2481-0.053.88% (683) PE-PGRS family protein
M. marinum MMMAR_2492-0.055.09% (639) PE-PGRS family protein, PE_PGRS15_2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0896cPE_PGRS150.058.59% (623) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-12251.28% (507) triple helix repeat-containing collagen
M. tuberculosis H37RvRv0872cPE_PGRS150.058.71% (620) PE-PGRS family protein
M. leprae Br4923MLBr_01183-2e-1035.42% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-5036.21% (428) hypothetical protein MAB_4284c
M. avium 104MAV_4827-2e-2343.68% (174) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-2e-9539.78% (626) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-8e-4339.51% (286) PUTATIVE -
M. ulcerans Agy99MUL_3318-1e-15950.16% (644) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-12146.32% (598) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb0896c|M.bovis_AF2122/97           --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4149|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4149|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           ------------------------------------------MSYVLATP
Rv0872c|M.tuberculosis_H37Rv        ------------------------------------------MSYVLATP
MMAR_4149|M.marinum_M               ------------------------------------------MSFVVVSP
MUL_3318|M.ulcerans_Agy99           ------------------------------------------MSYLAIAP
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          -----------------------------------------MPLFLNAEP
MAV_4827|M.avium_104                -------------------------------------MNIVLGVSMAPSS
                                                                                      

Mb0896c|M.bovis_AF2122/97           ----------------------------------------EMVAAAANNL
Rv0872c|M.tuberculosis_H37Rv        ----------------------------------------EMVAAAANNL
MMAR_4149|M.marinum_M               ----------------------------------------EVLAVAGRDL
MUL_3318|M.ulcerans_Agy99           ----------------------------------------EIVAAAAADM
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------VEAASYVADPEAAL
MLBr_01183|M.leprae_Br4923          ----------------------------------------QALTAAANTL
MAV_4827|M.avium_104                ----------------------------------------IQMVVLEGEY
                                                                                      

Mb0896c|M.bovis_AF2122/97           AQ----------------------IGSTLS--------------AANAAA
Rv0872c|M.tuberculosis_H37Rv        AQ----------------------IGSTLS--------------AANAAA
MMAR_4149|M.marinum_M               AS----------------------IGSAIS--------------QANVAA
MUL_3318|M.ulcerans_Agy99           DG----------------------IGSPIT--------------AANAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AN----------------------AGLSAVS-------------AAQVGA
MLBr_01183|M.leprae_Br4923          EG----------------------LSAATV--------------ASNAAA
MAV_4827|M.avium_104                AD-----------------------GATVEED------------AIDVTG
                                                                                      

Mb0896c|M.bovis_AF2122/97           LAP-------TTGVLAAGADEVSAAVASLFSGHAQAYQTLGTQAAAFHER
Rv0872c|M.tuberculosis_H37Rv        LAP-------TTGVLAAGADEVSAAVASLFSGHAQAYQTLGTQAAAFHER
MMAR_4149|M.marinum_M               AAP-------TMGALAAGADEVSAAVAAVFSGHAQAYQALGAQVAAFHDQ
MUL_3318|M.ulcerans_Agy99           AIP-------TSAIAAAAADEISAAIAELFGNHAQQYQALSAQMARFHDQ
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      -----------------------VDGDGGSGGRTGLFSKLSRGG----DG
MAB_4284c|M.abscessus_ATCC_199      VMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPS
MLBr_01183|M.leprae_Br4923          AQL-------TTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQD
MAV_4827|M.avium_104                ADD---------AATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ
                                                                   .                  

Mb0896c|M.bovis_AF2122/97           FIQALSTAAG-----AYGSAEAANASPLQQALNVIN-------------A
Rv0872c|M.tuberculosis_H37Rv        FIQALSTAAG-----AYGSAEAANASPLQQALNVIN-------------A
MMAR_4149|M.marinum_M               LVTALDAAAG-----KYASAEVANASPLQAVLDVVN-------------A
MUL_3318|M.ulcerans_Agy99           FVRSLSGAAQ-----TYARAEATGAAPLQPVLDLIN-------------G
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGLGGNGG-----------HGGGTGIISLLSLAG--------------
MAB_4284c|M.abscessus_ATCC_199      LLSPRDNDFLS-----HNDTDFASHNPIASGNQVMS--------PSGNVD
MLBr_01183|M.leprae_Br4923          LIQSLLTSSS-----AYAGTETANHDSL----------------------
MAV_4827|M.avium_104                LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGG---------AMGYE
                                                                                      

Mb0896c|M.bovis_AF2122/97           PTQTLLG------RPLIGNGTNGAPGTGQAGGPGG-------------LL
Rv0872c|M.tuberculosis_H37Rv        PTQTLLG------RPLIGNGTNGAPGTGQAGGPGG-------------LL
MMAR_4149|M.marinum_M               PAQALLG------RPLIGNGDDGVAGTGQSGGDGG-------------IL
MUL_3318|M.ulcerans_Agy99           PTQALLG------RPLIGNGTSGALGTGQAGGDGG-------------LL
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      ---------------NGGNGGNGYRTTDNNALDGG---------------
MAB_4284c|M.abscessus_ATCC_199      SFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGS---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                RTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAES--------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           YGN------------------------GGNGGSG----------------
Rv0872c|M.tuberculosis_H37Rv        YGN------------------------GGNGGSG----------------
MMAR_4149|M.marinum_M               YGN------------------------GGDGGSG----------------
MUL_3318|M.ulcerans_Agy99           IGNGTSGALGTGQAGGD---GGLLIGNGGAGGSG----------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      -----------------------------HGGNG----------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------NSGPIASGQG----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------YGDAAGQLS---------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           ---------------GVGQAGGAG--------------------------
Rv0872c|M.tuberculosis_H37Rv        ---------------GVGQAGGAG--------------------------
MMAR_4149|M.marinum_M               ---------------ASGQIGGTG--------------------------
MUL_3318|M.ulcerans_Agy99           ---------------AAGQAGGAGGAG-----------------------
Mflv_5091|M.gilvum_PYR-GCK          AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1       AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      -----------------GNVG-----------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------STAVNGDVR--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------AMVAGLEKLESLP------------------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           -----GSAGLIG---------------IGGTGGAGGAGAVGGVGGNGGWL
Rv0872c|M.tuberculosis_H37Rv        -----GSAGLIG---------------IGGTGGAGGAGAVGGVGGNGGWL
MMAR_4149|M.marinum_M               -----GSAGLIG---------------AGGTGGAGGLGAAGGAGGNGGWL
MUL_3318|M.ulcerans_Agy99           -----GAAGLIG---------------SGGAGGIGGTGAAGGKGGN-AVL
Mflv_5091|M.gilvum_PYR-GCK          GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1       QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      ------FFSLFN---------------LGGAGGWGGSGVDG---------
MAB_4284c|M.abscessus_ATCC_199      ------DSNIIN-------------ADHGSNVGVDQSQTRVGGDYTNVSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----GGLLLVG-------------------SGVDVAPLKQVLQTTTFLD
                                                                                      

Mb0896c|M.bovis_AF2122/97           YGNGG-AGGLGGTGVAGVNGGMGAAGGAGGN-------------------
Rv0872c|M.tuberculosis_H37Rv        YGNGG-AGGLGGTGVAGVNGGMGAAGGAGGN-------------------
MMAR_4149|M.marinum_M               FGQGG-AGGIGGS---------GAAGGAGGNG------------------
MUL_3318|M.ulcerans_Agy99           FGAGG-NGGIGGTGAVG---GTGAVGGAGGNG------------------
Mflv_5091|M.gilvum_PYR-GCK          -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      ---------------------VDVVGGNP---------------------
MAB_4284c|M.abscessus_ATCC_199      HGSADIDKSVTVVDDHSQRNTTNINDSFNTDR------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VSVAEEPETALARGAALAAANAPLFASSTAAL------------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           ----AYLFGSGGAGGQGG-------------------------MGAAGAD
Rv0872c|M.tuberculosis_H37Rv        ----AYLFGSGGAGGQGG-------------------------MGAAGAD
MMAR_4149|M.marinum_M               ----GWLYGDGGAGGQGG-------------------------AAAESIN
MUL_3318|M.ulcerans_Agy99           ----GFLFGHGGDGGTGG-------------------------TGASAAA
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      ---------DGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199      ----STNIGSGNTTNTEIG------------------------SHNQANI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----AYAQDPGTGAVDQYS-----------------------LPDYLYV
                                                                                      

Mb0896c|M.bovis_AF2122/97           GVNPTPTGT-----------------------------------------
Rv0872c|M.tuberculosis_H37Rv        GVNPTPTGT-----------------------------------------
MMAR_4149|M.marinum_M               --DGSPGQG-----------------------------------------
MUL_3318|M.ulcerans_Agy99           GANGGAGQTG----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      HTPGVYTDR-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GTSTSAGGS-----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PVDPEPGDDE----------------------------------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           ------------ADAGSTGTDQTLG-GNAIG-------------------
Rv0872c|M.tuberculosis_H37Rv        ------------ADAGSTGTDQTLG-GNAIG-------------------
MMAR_4149|M.marinum_M               ------------GNGGSAYLFGNGG-SGGQG-------------------
MUL_3318|M.ulcerans_Agy99           ---------LAGTDGGTGGASGEGG-AGGKGGLLF---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      --------------QGEDGEDGTGT-------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------AAVGGNAGLAGNAGLAGNAG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------LAYSAVGEEDAESPTVVIEKLFLP---------------
                                                                                      

Mb0896c|M.bovis_AF2122/97           ----GNGGPGDAGDAMTSGGAG-GSGGNAVSTVNGDAVGGEGGK---GGE
Rv0872c|M.tuberculosis_H37Rv        ----GNGGPGDAGDAMTSGGAG-GSGGNAVSTVNGDAVGGEGGK---GGE
MMAR_4149|M.marinum_M               ----GTGLAGADGVNYSNGTAGPGAWGNNVTTSIGDANGGNGGSGADGGA
MUL_3318|M.ulcerans_Agy99           ----GAGGEGGAGGTGGAGGTG-GAGGDGLAATTAGGTGGNAGDGGEGGA
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTG-GTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTG-GTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGAN-GNGGAGGAGGVSEGEGGTGGHGGDGGR
TH_3810|M.thermoresistible__bu      ----GIGGRGGNGGS-SSGTHPMAEDGEHVKALDG-RPGLDGGNGSHGGN
MAB_4284c|M.abscessus_ATCC_199      --LAGNAGLAGNAGLAGNAGLA-GNAGLAGNAGLAGNAGLAGNAGLAGNA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------EDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTV
                                                                                      

Mb0896c|M.bovis_AF2122/97           GAYGGAGGAGGSA----ASIGN---AAIGGNG---------GAGGNAQAP
Rv0872c|M.tuberculosis_H37Rv        GAYGGAGGAGGSA----ASIGN---AAIGGNG---------GAGGNAQAP
MMAR_4149|M.marinum_M               GVTGGTGGVGGFA----NNEGSG--DANGGFG---------GTGGNGGAP
MUL_3318|M.ulcerans_Agy99           GGNAGAGGAGGQG----GLFGNAGTTGAGGDG---------GNGGNGGLA
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_3810|M.thermoresistible__bu      GGHGGRGGFLGIG-------------GSGGWG---------GHGGNGGDT
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAG-----LAGNAGLAGNAGLAG------NAGLAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ALQPTPNQHLIVP------------TEQAPAPP--------PVQASAPQP
                                                                                      

Mb0896c|M.bovis_AF2122/97           GGV--------------GGAGGEGGDAQVGTNSPSNAEA-----------
Rv0872c|M.tuberculosis_H37Rv        GGV--------------GGAGGEGGDAQVGTNSPSNAEA-----------
MMAR_4149|M.marinum_M               GAS--------------GGEGGTGG---VAIASGGNAYG-----------
MUL_3318|M.ulcerans_Agy99           GN---------------GGAGGNGDASNPNGGTGGNAANPGAG-------
Mflv_5091|M.gilvum_PYR-GCK          GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1       GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155      GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
TH_3810|M.thermoresistible__bu      DAD--------------GGNGGDGG-------NGGSAGR-----------
MAB_4284c|M.abscessus_ATCC_199      GNAG------------LAGNAGLAGNAGLAGNAGLAGNAAVAG-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                KISVP---------EPVAAPKPLSPPVAAPLPAAPPPAAPPLP-------
                                                                                      

Mb0896c|M.bovis_AF2122/97           -------GNGGSGGNGFDSFASGGTG-----------------------G
Rv0872c|M.tuberculosis_H37Rv        -------GNGGSGGNGFDSFASGGTG-----------------------G
MMAR_4149|M.marinum_M               -------GSGGTGGNGATG-ASGGTG-----------------------G
MUL_3318|M.ulcerans_Agy99           -------GAGGAGGNGSRTGAPGTTGNTPTTAA----------------G
Mflv_5091|M.gilvum_PYR-GCK          --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1       --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155      GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
TH_3810|M.thermoresistible__bu      ---------GGTGGLRGVFGINGGNGR---------------------AG
MAB_4284c|M.abscessus_ATCC_199      --------NAAVAGNAAVAGNAAVGGVLN-------------------TG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------EAPPIPAAPPVVPVPVVVPPVP-------------------VP
                                                                                      

Mb0896c|M.bovis_AF2122/97           AGGTGGA-------------GGRGG--LLIGDGGAG--------GAGGVG
Rv0872c|M.tuberculosis_H37Rv        AGGTGGA-------------GGRGG--LLIGDGGAG--------GAGGVG
MMAR_4149|M.marinum_M               TGGTGGD-------------GGHGG--LLIGNGGIG--------GIGGTG
MUL_3318|M.ulcerans_Agy99           HGGKGGDGFNPATSGQDGGSGGKGGDAGQFGNGGNG--------GNGAAG
Mflv_5091|M.gilvum_PYR-GCK          QGGTGGT-------------GGQGGTGGTGGTGGTG--------GTGGAG
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGT-------------GGQGGTGGTGGTGGTG--------GTGGAG
MSMEG_0868|M.smegmatis_MC2_155      HGGSGIN-------------GGHGGNGGQGTIEANGPSAVASGIGAGGNG
TH_3810|M.thermoresistible__bu      LGGRGXX----------------------XXGGGVG---------AAVRS
MAB_4284c|M.abscessus_ATCC_199      VSGAIGG-------------SSHVGGAINESLGGSGS------VGGSTAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPVRIPVP-------------DPVSPPQLLAPPRLSVP-----QPVQPPV
                                                                                      

Mb0896c|M.bovis_AF2122/97           GTGGSGAPGGGG-AGGDGGAANTDSAGSSRKAFGGDGGVGGDGASALGTG
Rv0872c|M.tuberculosis_H37Rv        GTGGSGAPGGGGGAGGDGGAANTDSAGSSRKAFGGDGGVGGDGASALGTG
MMAR_4149|M.marinum_M               GVGGIGGTGGDGGTGGVGGSALNTGSGVADANIGGDGGDAGTG----GDG
MUL_3318|M.ulcerans_Agy99           DAAGSGHTGGNGGAGGGGGNAGQFGE-PGTGGSGGNGGKGGDGAAG-GNG
Mflv_5091|M.gilvum_PYR-GCK          GDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGL
Mvan_1264|M.vanbaalenii_PYR-1       GDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGL
MSMEG_0868|M.smegmatis_MC2_155      GDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGN
TH_3810|M.thermoresistible__bu      GNGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPSS-------
MAB_4284c|M.abscessus_ATCC_199      GGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                RVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGA
                                                                                      

Mb0896c|M.bovis_AF2122/97           GE-----GGIGGQGGNGGAGGLLIGNGGAGGVGGTAGAG-----------
Rv0872c|M.tuberculosis_H37Rv        GE-----GGIGGQGGNGGAGGLLIGNGGAGGVGGTAGAG-----------
MMAR_4149|M.marinum_M               GT-----GGVGGVGGSGGAGGLLFGNGGDGGAGGDGGVG-----------
MUL_3318|M.ulcerans_Agy99           GT-----GGIGGTGGIGGDG----RNGSTGAIGGNGGTG-----------
Mflv_5091|M.gilvum_PYR-GCK          FG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1       FG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155      GGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu      -------RAASARAGAACASSTSRSRRSFCCSRA----------------
MAB_4284c|M.abscessus_ATCC_199      GG----GVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGSGGSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTG-----------
                                                                                      

Mb0896c|M.bovis_AF2122/97           --GTGGSGGAGGA------GGAGGGG----------------TNSGPGAA
Rv0872c|M.tuberculosis_H37Rv        --GTGGSGGAGGA------GGAGGGG----------------TNSGPGAA
MMAR_4149|M.marinum_M               --GTGGIGGAGGN------GGVGGDG----------------SSSGTGAG
MUL_3318|M.ulcerans_Agy99           --GTGGTGGTGGKSLGNLPSGDGGVG----------------GNAGTGGN
Mflv_5091|M.gilvum_PYR-GCK          G-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA
Mvan_1264|M.vanbaalenii_PYR-1       G-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA
MSMEG_0868|M.smegmatis_MC2_155      GVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --GGAHTGVGGGVNTGVGVGSHVGGG--------------ISESLGGSGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------GSGGGHVPTPGAGTPGGSG-------------------GGHLP
                                                                                      

Mb0896c|M.bovis_AF2122/97           -FGGNGNTGGNG----------------------GNGGAPGALG------
Rv0872c|M.tuberculosis_H37Rv        -FGGNGNTGGNG----------------------GNGGAPGALG------
MMAR_4149|M.marinum_M               GSGGDATDGGTG----------------------GDGGSGGGFGTG----
MUL_3318|M.ulcerans_Agy99           --GGNATDGGAG----------------------GKGGDGAAGGTG----
Mflv_5091|M.gilvum_PYR-GCK          -NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-ING
Mvan_1264|M.vanbaalenii_PYR-1       -NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-ING
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGSTAVGGGAHTS-------------------AINDALGGSGSVG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                FPGAGSTPGGSG------------------------GGHLPTPGAG----
                                                                                      

Mb0896c|M.bovis_AF2122/97           GKGGSGG---------LIGRA--GSDGGVGAGGAGGA--------GGAGG
Rv0872c|M.tuberculosis_H37Rv        GKGGSGG---------LIGRA--GSDGGVGAGGAGGA--------GGAGG
MMAR_4149|M.marinum_M               GAGGTGGW--------LIGHS--GTNGIGGTGGAGGA--------GAVGG
MUL_3318|M.ulcerans_Agy99           GNAGEFQS--------LLGISKGGDGGTGGDGGTGTP--------VGADG
Mflv_5091|M.gilvum_PYR-GCK          GAGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGG
Mvan_1264|M.vanbaalenii_PYR-1       GAGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGG
MSMEG_0868|M.smegmatis_MC2_155      GDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSTAVGGG---------AHTSAINESMNSSINASHSS-------SMNESF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------TPGGGLGGFGGGHAPAPG--------GGLGG
                                                                                      

Mb0896c|M.bovis_AF2122/97           TGGEGGTGGDGKTTDGNPGMGGSPGSAGQPGQPG-------
Rv0872c|M.tuberculosis_H37Rv        TGGEGGTGGDGKTTDGNPGMGGSPGSAGQPG----------
MMAR_4149|M.marinum_M               DGGVGGDPGVGTTYNGISGHNGVQGGTGADGAAG-------
MUL_3318|M.ulcerans_Agy99           LAGTGGAGGFGIFPGGQTGQNGTDSKAG-------------
Mflv_5091|M.gilvum_PYR-GCK          GGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       SGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      NGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      -----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923          -----------------------------------------
MAV_4827|M.avium_104                GGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK---------