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SFLIAAPEMLTAAAADIATIGSTISAADAIAAAPTTSVLAAAADEVSLAIAGLFSAHAKQYQAFSVQAAT FHEQLVRSLAAGGFSYATAEAANASPLEFLLDAVNAPTQTLFGRDLIGNGTDGAAGTGANGGDGGLLWGN GGNGGSGATGQVGGSGGAAGLIGTGGTGGAGGTGAAGGNGGAGGWLFGDGGIGGTGGAGATGGSGGAGGV GFGSGGTGGFGGAGAAGGTGGDGALLWGNGGAGGQGGTGMTGINGGSAGHGGSGGNAVGLLGSGGAGGQG GTGLAGIDGVSSHGSGTASTGAAGTNVEHSTAPPPTEIYGGAGGPGGGGSLDSLNGGTGGAGGSATVHNT QNAIGGNGGDGGAAGLFAIGGNGGDGGRGGDALSDYSTVTGPSATGGNGGAGHDGHIGGGAGGTGGAGGN GTSADGVGHGGNGGIGGNGNSASNGGGDGGNGGAGGTGGHGGLLIGNGGAGGIGGTGGSGGAGAPGGIGG GGGGGGIGTATNLGIAAEGGLGGDGGGGGDTTAVGGNGGTGGVGGNGGNASAVFGFGGNGGASGTGGAGG AGGAGGAGGAGGAGGTSSVSGNIGAVGGNGGVGGDGGDGGDGGDGGAAGAAGGAGGQGGFLGSAGSAGGS GVGGAGGAAGNGGSAGAGGDGGVAAGTFGVNGSDGADGNQGAPGTAGQDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2481 | - | - | 100% (681) | PE-PGRS family protein |
| M. marinum M | MMAR_2067 | - | 0.0 | 50.83% (785) | PE-PGRS family protein |
| M. marinum M | MMAR_2490 | - | 0.0 | 53.60% (681) | PE-PGRS family protein, PE_PGRS15_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | 0.0 | 50.95% (681) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-130 | 46.31% (624) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0872c | PE_PGRS15 | 0.0 | 51.31% (686) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-15 | 42.71% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-49 | 33.62% (458) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-23 | 43.20% (169) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-112 | 41.47% (668) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-43 | 37.16% (331) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 1e-173 | 46.51% (789) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-133 | 46.57% (627) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_2481|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_2481|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_2481|M.marinum_M -----------------------------------------MS-FLIAAP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
Mb2878|M.bovis_AF2122/97 ------------------------------------------MLYVVASP
Rv0872c|M.tuberculosis_H37Rv ------------------------------------------MSYVLATP
MUL_0572|M.ulcerans_Agy99 ------------------------------------------MSYVVAIP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_2481|M.marinum_M ----------------------------------------EMLTAAAADI
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
Mb2878|M.bovis_AF2122/97 ----------------------------------------DLMTAAATNL
Rv0872c|M.tuberculosis_H37Rv ----------------------------------------EMVAAAANNL
MUL_0572|M.ulcerans_Agy99 ----------------------------------------DMLASAAADV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 ----------------------------------------IQMVVLEGEY
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MMAR_2481|M.marinum_M AT----------------------IGSTIS-----------AADAIAAAP
MLBr_01183|M.leprae_Br4923 EG----------------------LSAATV-----------ASNAAAAQL
Mb2878|M.bovis_AF2122/97 AE----------------------IGSAIS-----------TANGAAALP
Rv0872c|M.tuberculosis_H37Rv AQ----------------------IGSTLS-----------AANAAALAP
MUL_0572|M.ulcerans_Agy99 AG----------------------IGSSVG-----------AANTAAVGA
TH_3810|M.thermoresistible__bu -----------------------------------------VDGDGGSGG
MAB_4284c|M.abscessus_ATCC_199 AN----------------------AGLSAVS----------AAQVGAVMP
MAV_4827|M.avium_104 AD-----------------------GATVEED---------AIDVTGADD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MMAR_2481|M.marinum_M TTS-------VLAAAADEVSLAIAGLFSAHAKQYQAFSVQAATFHEQLVR
MLBr_01183|M.leprae_Br4923 TTE-------IAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQ
Mb2878|M.bovis_AF2122/97 TVE-------VVAAAADEVSTQIAALFGAHARSYQTLSTQAAAFHSRFVQ
Rv0872c|M.tuberculosis_H37Rv TTG-------VLAAGADEVSAAVASLFSGHAQAYQTLGTQAAAFHERFIQ
MUL_0572|M.ulcerans_Agy99 TTG-------VMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLR
TH_3810|M.thermoresistible__bu RTG--------------LFSKLSRGGDGGDGGLGGNGGHGGGTGIISLLS
MAB_4284c|M.abscessus_ATCC_199 VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MAV_4827|M.avium_104 AAT---------ASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVG-ATGAVG--APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAG-ATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADG-TSAHVDGGTGGTGGTGGGT
MMAR_2481|M.marinum_M ------------SLAAGGFSYATAEAANAS-PLEF----LLDAVNAPTQT
MLBr_01183|M.leprae_Br4923 ------------SLLTSSSAYAGTETANHD-SL-----------------
Mb2878|M.bovis_AF2122/97 ------------ALTTAAASYASVEAANAS-PLQV----ALDVINAPAQT
Rv0872c|M.tuberculosis_H37Rv ------------ALSTAAGAYGSAEAANAS-PLQQ----ALNVINAPTQT
MUL_0572|M.ulcerans_Agy99 ------------ALTGAGGAYAAAEAANAS-PLQAAEQEVLAVINAPTNA
TH_3810|M.thermoresistible__bu -------------LAGNGGNGGNGYRTTDNN-------------------
MAB_4284c|M.abscessus_ATCC_199 PRDND-------FLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLD
MAV_4827|M.avium_104 A-----------ALRDALAARRIDNVMLVS-AFLAAAALAQNVGGAMGYE
* .
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
MMAR_2481|M.marinum_M LFGRDLIG-----------NGTDGAAGTGANGGDGG-------------L
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 LLGRPLIG-----------NGADGST-PGQAGGPGG-------------L
Rv0872c|M.tuberculosis_H37Rv LLGRPLIG-----------NGTNGAPGTGQAGGPGG-------------L
MUL_0572|M.ulcerans_Agy99 LLGRPLIG-----------NGTDGLAGTGAAGGAGG-------------L
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LSFGDLQFG----------NRDTTAIGDGAVAVGGS--------------
MAV_4827|M.avium_104 RTAVLLVEP-------------DTATLAVVETSDGS-------------I
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG-----
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG-----
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
MMAR_2481|M.marinum_M LWGNGGNGGSGATGQVGGSGGAAGLIGTGGTGGAGGTGAAGGNGGAGGWL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 LYGNGGNGAAGGPNQAGGAGGNAGLIGNGGAGGAG---------------
Rv0872c|M.tuberculosis_H37Rv LYGNGGNGGSGGVGQAGGAGGSAGLIGIGGTGGAG---------------
MUL_0572|M.ulcerans_Agy99 LWGNGGNGGSGAAGQAGGAGGAAGLIGTGGAGGMGGAG------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --NSGPIASGQGSTAVNGDVRDSNIINADHGSNVG---------------
MAV_4827|M.avium_104 PDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPG---------------
Mflv_5091|M.gilvum_PYR-GCK --AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 --VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
MMAR_2481|M.marinum_M FGDGGIGGTGGAGATGGSGGAGGVGFGSG----GTGGFGGAGAAGGTGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ---------------------------------------GVGAVGGNGGT
Rv0872c|M.tuberculosis_H37Rv ---------------------------------------GAGAVGGVGGN
MUL_0572|M.ulcerans_Agy99 ---------GGAGGMGGSGGWLLGNGGAG----GAGGVGCAGVSGGVGGT
TH_3810|M.thermoresistible__bu --------------------------------------ALDGGHGGNGGN
MAB_4284c|M.abscessus_ATCC_199 --------------------------------VDQSQTRVGGDYTNVSGH
MAV_4827|M.avium_104 ---------------------------------GLLLVGSGVDVAPLKQV
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
MMAR_2481|M.marinum_M GA--LLWGNGGAG--------------------------GQGGTGMTGIN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 GG--LLFGNGGAG--------------------------GQGGLGLAGIN
Rv0872c|M.tuberculosis_H37Rv GG--WLYGNGGAG--------------------------GLGGTGVAGVN
MUL_0572|M.ulcerans_Agy99 GGNAMLFGNGGAG--------------------------GMGGAGADGAV
TH_3810|M.thermoresistible__bu VGFFSLFNLGGAG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSADIDKSVTVVD------------------------DHSQRNTTNINDS
MAV_4827|M.avium_104 LQTTTFLDVSVAE--------------------------EPETALARGAA
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
MMAR_2481|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GAAGTAGTSTSAGGVGGA------------GWDATAAGVLAATGGDGGDS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FN------------------------------------------------
MAV_4827|M.avium_104 L-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
MMAR_2481|M.marinum_M -----GGSAGHGGSGGNAVGLLGSGG------------------AGGQGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 -----GGSGGQGGHGGNAI-LFGQGG------------------AGGPGG
Rv0872c|M.tuberculosis_H37Rv -----GGMGAAGGAGGNAY-LFGSGG------------------AGGQGG
MUL_0572|M.ulcerans_Agy99 GGGGAGGNGGAGGAGGHGSALFGADG------------------ANGNGG
TH_3810|M.thermoresistible__bu ---------GWGGSGVDGVDVVGGNP---------------------DGG
MAB_4284c|M.abscessus_ATCC_199 -----TDRSTNIGSGNTTNTEIGSHN------------------QANIGT
MAV_4827|M.avium_104 -------AAANAPLFASSTAALAYAQ---------------------DPG
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
MMAR_2481|M.marinum_M TGLAGIDGVSSHGSG---------------TASTGAAGTN----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 TGAMGVAGTNPTPIG---------------TAAPGSDGVN----------
Rv0872c|M.tuberculosis_H37Rv MGAAGADGVNPTPTG---------------TADAGSTGTD----------
MUL_0572|M.ulcerans_Agy99 AGGAGGNPGAPGNGG---------------TGGVGPDAAT----------
TH_3810|M.thermoresistible__bu TPGAHGESHTPGVYTD----------------------------------
MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVGGNAG---------------LAGNAGLAGN----------
MAV_4827|M.avium_104 TGAVDQYSLPDYLYVP----------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
MMAR_2481|M.marinum_M --------------VEHSTAPPPTEIYGGAGGPGGG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------QIGNGGNTDLTGGAGGDGNAGS--------------
Rv0872c|M.tuberculosis_H37Rv --------------QTLGG---NAIGGNGGPGDAGD--------------
MUL_0572|M.ulcerans_Agy99 --------------SGGMGGTGGDPGAVGGRGNSGA--------------
TH_3810|M.thermoresistible__bu --------------RQGEDGEDGTGTGIGGRGGNGG--------------
MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAGNAGLAGNAGLAGN--------------
MAV_4827|M.avium_104 --------------VDPEPGDDELAYSAVGEEDAESP-------------
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTG------------GTG-GT
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTG------------GTG-GT
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG------------GVSEGE
MMAR_2481|M.marinum_M ---GSLDSLNGGTGGAGGSATVHNTQNAIGG---------------NGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ---TTVNGGNGGTGGA-ARNSSGGTGNSFGG---------------AGGA
Rv0872c|M.tuberculosis_H37Rv ---AMTSGGAGGSGGN-AVSTVN--GDAVGG---------------EGGK
MUL_0572|M.ulcerans_Agy99 ---AGGAGAVAGASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNGGD
TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDGEHVKALDGRPGLDGGNG-------------SHGGN
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAG--------------NAGL
MAV_4827|M.avium_104 --TVVIEKLFLPEDSEPRRRPVLLVGSGLAVVG------------ISAVL
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDP
MMAR_2481|M.marinum_M GGAAGLFAIGGNGGDGGRGGDALSDYSTVTGPSATGGNGGAGHDG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 GGDG------ANGGDGGAGGEALTEGGATAVSGAGGKGGNAEASG-----
Rv0872c|M.tuberculosis_H37Rv GGEG------AYGGAGGAGGSAASIG-NAAIGGNGGAGGNAQAPG-----
MUL_0572|M.ulcerans_Agy99 GGHGGAGGFYGNGGAGGAGGNSAPGGGTGGNGGTGGDSGAMGSSGG--RG
TH_3810|M.thermoresistible__bu GGHGGRGGFLGIGGSGGWGGHGGNGGDTDADGGNGGDGGNGGSAG-----
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAG-NAGLAGNAGLAGNAGLAGN----
MAV_4827|M.avium_104 ALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQP----
Mflv_5091|M.gilvum_PYR-GCK ---GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGG
MSMEG_0868|M.smegmatis_MC2_155 SHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGG
MMAR_2481|M.marinum_M ---HIGGGAGGTGGA---------------GGNGTSADGVGHGGNGGIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ---GAGG-NGGKGGF---------------AQATTS----VTGGNGGNGG
Rv0872c|M.tuberculosis_H37Rv ---GVGG-AGGEGGD---------------AQVGTNSPSNAEAGNGGSGG
MUL_0572|M.ulcerans_Agy99 GDGGVGTNGGAGGGG---------------GNATSYGTANATGGAGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAG------------------NAAVAGNAAVAGNAAVAGN
MAV_4827|M.avium_104 ---KISVPEPVAAPKP--------------LSPPVAAPLPAAPPPAAPPL
Mflv_5091|M.gilvum_PYR-GCK QGG-----------------TGGTGGQGG-LGGGGGTG------------
Mvan_1264|M.vanbaalenii_PYR-1 QGG-----------------TGGTGGQGG-LGGVGGTG------------
MSMEG_0868|M.smegmatis_MC2_155 DGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQ
MMAR_2481|M.marinum_M NGNS------------ASN-GGGDGGNGG-AGGTGGHG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 NGHD------------SNA-PGGAGGSGG-VGGDGGRG------------
Rv0872c|M.tuberculosis_H37Rv NGFD------------SFA-SGGTGGAGG-TGGAGGRG------------
MUL_0572|M.ulcerans_Agy99 TGST------------GNGGSGGDGGNGG-TGHGGGGGPGGTAINYG---
TH_3810|M.thermoresistible__bu --------------------RGGTGGLRGVFGINGGNG------------
MAB_4284c|M.abscessus_ATCC_199 AAVG----------------GVLNTGVSGAIGGSSHVG------------
MAV_4827|M.avium_104 PEAP------------------PIPAAPPVVPVPVVVP------------
Mflv_5091|M.gilvum_PYR-GCK -----------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGG
MSMEG_0868|M.smegmatis_MC2_155 ANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGG
MMAR_2481|M.marinum_M ----------------GLLIGNGGAGGIGGTGGSG--------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ----------------GLLAGNGGTGGAGGNGGTG--------------G
Rv0872c|M.tuberculosis_H37Rv ----------------GLLIGDGGAGGAGGVGGTG--------------G
MUL_0572|M.ulcerans_Agy99 -----------AGDAFGGAAGKGGTGVVGGNGGSGG--------AAYNYG
TH_3810|M.thermoresistible__bu ------------------RAGLGGRGXXXXGGGVG---------AAVRSG
MAB_4284c|M.abscessus_ATCC_199 ---------------GAINESLGGSGSVGGSTAVG---------------
MAV_4827|M.avium_104 ----------------PVPVPVPVRIPVPDPVSPP--------------Q
Mflv_5091|M.gilvum_PYR-GCK DGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLF
Mvan_1264|M.vanbaalenii_PYR-1 DGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLF
MSMEG_0868|M.smegmatis_MC2_155 DGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNG
MMAR_2481|M.marinum_M AGAPGGIGGGGGGGGIGTATNLGIA--AEGGLGGDGGGGGD---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 AGAPGGAGGAGGKADIAN--SLGDNATVTGGNGGTGGDGGS---------
Rv0872c|M.tuberculosis_H37Rv SGAPGGGGGAGGDGGAANTDSAGSSRKAFGGDGGVGGDGAS---------
MUL_0572|M.ulcerans_Agy99 TGNATGAGGSSGSGGAASVPNSASTATATSGSGGAGGDGTDGGNGGSGGF
TH_3810|M.thermoresistible__bu NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPS---------
MAB_4284c|M.abscessus_ATCC_199 GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG--------
MAV_4827|M.avium_104 LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTP--------
Mflv_5091|M.gilvum_PYR-GCK G----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG
Mvan_1264|M.vanbaalenii_PYR-1 G----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG
MSMEG_0868|M.smegmatis_MC2_155 GPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTG
MMAR_2481|M.marinum_M --------------------TTAVGGNGGTGG-------------VGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------ALGTGGAGGAGG-------------LGGHG
Rv0872c|M.tuberculosis_H37Rv --------------------ALGTGGEGGIGG-------------QGGNG
MUL_0572|M.ulcerans_Agy99 AFTFGTGNIIAGVGGGGGTGSTGVGGIGGSGGGADINNGAFTVVPQGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------GGAHTGVGGGVSTG--------------VGVG
MAV_4827|M.avium_104 ---------------------PGEGTPPKPDG-------------PGNYG
Mflv_5091|M.gilvum_PYR-GCK -ATGAAGKAGATGAAGAAGAAGSAG--------------TTGAQGSAGTN
Mvan_1264|M.vanbaalenii_PYR-1 -ATGASGAQGSAGSAGSAGVAGSAG--------------TTGAQGSAGTN
MSMEG_0868|M.smegmatis_MC2_155 VATGNTATGGDGGAATTAGATGGAGGFSNI---AAIHGAITDSTAISGHG
MMAR_2481|M.marinum_M ---------GNASAVFGFGGNGGAS-------------GTGGAGGAGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ---------GAGGLLIGNGGAGGAG-------------GLGGAGGAGGAG
Rv0872c|M.tuberculosis_H37Rv ---------GAGGLLIGNGGAGGVG-------------GTAGAGGTGGSG
MUL_0572|M.ulcerans_Agy99 ---------GHGGDGATDGGAGGAGGFTEIDSSASVIAATGGAGGDGGSG
TH_3810|M.thermoresistible__bu ----------SRAASARAGAACASS--------------TSRSRRSFCCS
MAB_4284c|M.abscessus_ATCC_199 -------SHVGGGISESLGGSGSVGG-----------STAVGGGAHTGVG
MAV_4827|M.avium_104 ---------GGHVPTPGAGGSGGSGG---------GHVPTPGAGGSGGSG
Mflv_5091|M.gilvum_PYR-GCK GA-NGANGSQGAAG----KAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1 GA-NGANGSQGAAG----KAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155 GAGNGGNGGKGADG----WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
MMAR_2481|M.marinum_M GAG----GAGGAGG-TSSVSGNIGAVGGNG-------GVGGDGGDGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 GEG----GAGGAGGEAIPGGASTNSAGGDG-------GAGGTGGNGGDGG
Rv0872c|M.tuberculosis_H37Rv GAG----GAGGAGG----GGTNSGPGAAFG-------GNGNTGGNGGNGG
MUL_0572|M.ulcerans_Agy99 GTGRGGTGGGGTGGGGTGGGGGVGINNGSGEAIGGAPGAGGTGAVGGDGG
TH_3810|M.thermoresistible__bu RA------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGVNTGVGVGSHVG-----GGISESLGGSG-------SVGGSTAVGGGAH
MAV_4827|M.avium_104 GGHVPTPGTGGPGGTGGSGGGHVPTPG------------AGTPGGSGGGH
Mflv_5091|M.gilvum_PYR-GCK SG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-------
Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-------
MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEP-----G
MMAR_2481|M.marinum_M DGGAAGAAGGAGGQGG-----FLGSAGSAGGSGVGGAGGAA---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 AGGAPGLGGAGGAGGW-----LIGQSGSTGGGGAGGAGGAG---------
Rv0872c|M.tuberculosis_H37Rv APGA--LGGKGGSGG------LIGRAGSDGGVGAGGAGGAG---------
MUL_0572|M.ulcerans_Agy99 QGGAAYSYGTGDATG------SAGAAGTAGTTGVGGTGGAGGAAYTLNGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINDALGGSGSVGG-----STAVGGGAHTSAINESMNSSIN-------
MAV_4827|M.avium_104 LPFPGAGSTPGGSGGG----HLPTPGAGTPGGGLGGFGGGHAP-------
Mflv_5091|M.gilvum_PYR-GCK ------GGAGGGGGAGGSGAGGAG--GAGGS-------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------GGAGGSGGAGGSGTGGAG--GAGGS-------------------
MSMEG_0868|M.smegmatis_MC2_155 PGGNGAGGAGGNGGTGGTTAGGSGNGGNGGN-------------------
MMAR_2481|M.marinum_M ----GNGGSAGAGGDGGVAAGTFGVNG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ----GAGGAGGSGGAGGHGDTTSGKNG-----------------------
Rv0872c|M.tuberculosis_H37Rv ----GAGGTGGEGGTGGDGKTTDGNPG-----------------------
MUL_0572|M.ulcerans_Agy99 STATATGGIGGNGGDGGTANGSNGGNGGAGGYASTTGTGTASVGNGGRGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----ASHSSSMNESFGSSMGSHGAAGTGFEAQG----------------
MAV_4827|M.avium_104 ------APGGGLGGGGGHAPAPGGGLG-----------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------GGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------GGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 -----------------------------GGNGGADGTPGTAGTTGANNP
MMAR_2481|M.marinum_M -------------------------------SDGADGNQGAPGTAGQDG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 -------------------------------SSGTAGFDGNPGQPG----
Rv0872c|M.tuberculosis_H37Rv -------------------------------MGGSP---GSAGQPG----
MUL_0572|M.ulcerans_Agy99 DGTATVATGGTGGVGGNAHAPAGSPVPGVGGKGGNPGPGGKPGPNGADGI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------HAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 ------------------------------GFGGGHSGGGLGGLGGGHK-
Mflv_5091|M.gilvum_PYR-GCK --
Mvan_1264|M.vanbaalenii_PYR-1 --
MSMEG_0868|M.smegmatis_MC2_155 --
MMAR_2481|M.marinum_M --
MLBr_01183|M.leprae_Br4923 --
Mb2878|M.bovis_AF2122/97 --
Rv0872c|M.tuberculosis_H37Rv --
MUL_0572|M.ulcerans_Agy99 VV
TH_3810|M.thermoresistible__bu --
MAB_4284c|M.abscessus_ATCC_199 --
MAV_4827|M.avium_104 --