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SFLIAAPDMVAAAATDLASIGSTINTANAAASALTTSVAAAAADEVSTAVAHVFDTYAQEYQTFGAHMAA FHDQFVQTLKTGALAYTGAEAANASPLQELLNAVNAPTQALLGRPLIGNGTDGAPGTGADGGAGGLLWGN GGNGGSGAAGQTGGDGGVAGLIGTGGNGGAGGIGAAGGMGGAAGLFGGGGVGGVGGAGAAGGSGGTGGLL LGDGGAGGMGGVGMAGVNGGVAGQGGSGGHAVLLGNGGAGGQGGTGMAGTDGTNPTPTGTAGTGASGTPF SGDGHAGSGHTGDNGAPGENGGTGGTGGEATGAGGIGGTGGNGGAAGSGGANGGDGGVGGAATDTFGFDN NQGGNGGNGANGSGPGGAGGAGGDGGASTAGGAATGGKGGHGGNGAASDLSGGNGGAAGAGGNGGNAGLL VGNGGAGGTGGVGGSGGTGAAGGAGGTGGDGGTATGNFDPTGTAAQGQEGGDGGSGADSTGIGGNGGNGG VGGNGGNGGRLLGLGGAGGDAGNGGVGGTGGAGGAGGAGGHGGNATSGQLSQGGNGGNGGGGGNGADGGD GGAAGLSGGNGGQGGLIGVSGVDGAAGIGGRAGAGGAGGALGAGGAGGIAEGLIHVDGDAGLNGVAGTSG NAGQHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2492 | - | - | 100% (637) | PE-PGRS family protein, PE_PGRS15_2 |
| M. marinum M | MMAR_2481 | - | 0.0 | 59.00% (683) | PE-PGRS family protein |
| M. marinum M | MMAR_2490 | - | 0.0 | 58.92% (650) | PE-PGRS family protein, PE_PGRS15_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0896c | PE_PGRS15 | 0.0 | 55.62% (649) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-124 | 48.22% (591) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0872c | PE_PGRS15 | 0.0 | 55.57% (646) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-14 | 39.58% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-47 | 33.64% (434) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 9e-23 | 43.50% (177) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-97 | 40.06% (694) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-43 | 39.25% (321) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 1e-167 | 49.44% (712) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-119 | 47.11% (554) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0896c|M.bovis_AF2122/97 ---------------MSYVLATPEMVAAAAN-------------------
Rv0872c|M.tuberculosis_H37Rv ---------------MSYVLATPEMVAAAAN-------------------
MMAR_2492|M.marinum_M ---------------MSFLIAAPDMVAAAAT-------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_4367|M.ulcerans_Agy99 ---------------MSFVSVGPGLLEAAARDLAG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFR-----------------------
MAV_4827|M.avium_104 ----------------MNIVLGVSMAPSSIQ-------------------
Mb0896c|M.bovis_AF2122/97 NLAQIGSTLSAANAAALAPTTGVLAAGADEVSAAVASLFSGHAQAYQTLG
Rv0872c|M.tuberculosis_H37Rv NLAQIGSTLSAANAAALAPTTGVLAAGADEVSAAVASLFSGHAQAYQTLG
MMAR_2492|M.marinum_M DLASIGSTINTANAAASALTTSVAAAAADEVSTAVAHVFDTYAQEYQTFG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MUL_4367|M.ulcerans_Agy99 ----LGAGLREANLAAAGATVGVLPAAGDEVSAAIAELFGG--FGREYQA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --DPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQS
MAV_4827|M.avium_104 --MVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAA
Mb0896c|M.bovis_AF2122/97 ------------------------------------TQAAAFHERFIQAL
Rv0872c|M.tuberculosis_H37Rv ------------------------------------TQAAAFHERFIQAL
MMAR_2492|M.marinum_M ------------------------------------AHMAAFHDQFVQTL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MUL_4367|M.ulcerans_Agy99 MGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNAPSM
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------QWVNTGNPIHDLS
MAV_4827|M.avium_104 DAG---------------------------------LQLSSIGVTWTDQL
Mb0896c|M.bovis_AF2122/97 STAAG-----------------------------------AYGSAEAANA
Rv0872c|M.tuberculosis_H37Rv STAAG-----------------------------------AYGSAEAANA
MMAR_2492|M.marinum_M KTGAL-----------------------------------AYTGAEAANA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MUL_4367|M.ulcerans_Agy99 ALFGR-----------------------------------PSIGNGVDGV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNLQN------------------------------------YYAAQPDGP
MAV_4827|M.avium_104 EAAALR--------------------------------------------
Mb0896c|M.bovis_AF2122/97 SP---------------------------------------LQQALNVIN
Rv0872c|M.tuberculosis_H37Rv SP---------------------------------------LQQALNVIN
MMAR_2492|M.marinum_M SP---------------------------------------LQELLNAVN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MUL_4367|M.ulcerans_Agy99 AG-------------------TGQAGGAGGILWGNGGNGGLGAAGANGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SILS---------------------------------PSLLSPRDNDFLS
MAV_4827|M.avium_104 --------------------------------------DALAARRIDNVM
Mb0896c|M.bovis_AF2122/97 APTQTLLGRPLIGNGTNGAPG-----TGQAGGPGGLLYGNGGNGGSGGVG
Rv0872c|M.tuberculosis_H37Rv APTQTLLGRPLIGNGTNGAPG-----TGQAGGPGGLLYGNGGNGGSGGVG
MMAR_2492|M.marinum_M APTQALLGRPLIGNGTDGAPG-----TGADGGAGGLLWGNGGNGGSGAAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MUL_4367|M.ulcerans_Agy99 GGSAGLIGTGGVGGAGGVGAAGMTGGSGGAGGGGGWLWGAGGSGGAAGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTA
MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY
Mb0896c|M.bovis_AF2122/97 QAGGAG----GSAG---LIGIGGTGGAG----------------------
Rv0872c|M.tuberculosis_H37Rv QAGGAG----GSAG---LIGIGGTGGAG----------------------
MMAR_2492|M.marinum_M QTGGDG----GVAG---LIGTGGNGGAGGIGAAG----------GMGGAA
TH_3810|M.thermoresistible__bu GDGGSG----GRTGLFSKLSRGGDGGDGGLG-------------GNGGHG
Mflv_5091|M.gilvum_PYR-GCK GNGGNG----GNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNG----GDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGAT
MSMEG_0868|M.smegmatis_MC2_155 LDGGNG----GSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
MUL_4367|M.ulcerans_Agy99 GSGGSGGWLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVSG-VAPGEAGAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGDGAVAVG-GSNSGPIASGQGSTAVNGDVRDSNIIN-------ADHGSN
MAV_4827|M.avium_104 KQQIRAESYGDAAGQLSAMVAGLEKLESLPG-------------GLLLVG
Mb0896c|M.bovis_AF2122/97 --------------------------GAGAVGGVGGNGG-----------
Rv0872c|M.tuberculosis_H37Rv --------------------------GAGAVGGVGGNGG-----------
MMAR_2492|M.marinum_M GLFGGGG--------------VGGVGGAGAAGGSGGTGG-----------
TH_3810|M.thermoresistible__bu GGTGIIS--------------------LLSLAGNGGNGG-----------
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVL---
MUL_4367|M.ulcerans_Agy99 GFAGGAGGAGGAGGNGVGG-GVNGAGGAGGAGGVGGGGGAGASGVGAGVA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRN-----------
MAV_4827|M.avium_104 SGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAAN----------
Mb0896c|M.bovis_AF2122/97 --------------------------------------------------
Rv0872c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2492|M.marinum_M --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----
Mvan_1264|M.vanbaalenii_PYR-1 -----------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----
MSMEG_0868|M.smegmatis_MC2_155 -----IAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAI
MUL_4367|M.ulcerans_Agy99 GGDGGTGGAGGAAGVGGAAGTGGTGGAAGVAGTGGDGGDGGAGGAGSDAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0896c|M.bovis_AF2122/97 ------------WLYGNGGAGGLGGTGVAGVNGGMGAAG-----------
Rv0872c|M.tuberculosis_H37Rv ------------WLYGNGGAGGLGGTGVAGVNGGMGAAG-----------
MMAR_2492|M.marinum_M ------------LLLGDGGAGGMGGVGMAGVNGGVAGQG-----------
TH_3810|M.thermoresistible__bu --------------------NGYRTTDNNALDGGHGGNG-----------
Mflv_5091|M.gilvum_PYR-GCK AVGAAG-------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAG-------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTG
MSMEG_0868|M.smegmatis_MC2_155 LIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTA
MUL_4367|M.ulcerans_Agy99 LAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGGAGAAG-------GAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------TTNINDSFNTDRSTNIGSGNTTNTEIG-----------
MAV_4827|M.avium_104 ----------------APLFASSTAALAYAQDPGTGAVD-----------
Mb0896c|M.bovis_AF2122/97 ------GAGGNAYLFGSGGAGGQG--------------------GMGAAG
Rv0872c|M.tuberculosis_H37Rv ------GAGGNAYLFGSGGAGGQG--------------------GMGAAG
MMAR_2492|M.marinum_M ------GSGGHAVLLGNGGAGGQG--------------------GTGMAG
TH_3810|M.thermoresistible__bu ------GNVGFFSLFNLGGAGGWG--------------------GSGVDG
Mflv_5091|M.gilvum_PYR-GCK AAGAAGGAGGLGETGTTGGAGGVG--------------------GQGTAG
Mvan_1264|M.vanbaalenii_PYR-1 AAGAAGQAGTAGETGVTGGVGGIG--------------------GQGTEG
MSMEG_0868|M.smegmatis_MC2_155 EGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDG
MUL_4367|M.ulcerans_Agy99 ASATVAGSGGVGGDGGAGGAAGGG-------------VGAASLGGDGGHA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----SHNQANIGTSTSAGGSAAVG-------------------GNAGLAG
MAV_4827|M.avium_104 -------QYSLPDYLYVPVDPEPG--------------------DDELAY
Mb0896c|M.bovis_AF2122/97 -----------------------ADGVNP---------------------
Rv0872c|M.tuberculosis_H37Rv -----------------------ADGVNP---------------------
MMAR_2492|M.marinum_M -----------------------TDGTNP---------------------
TH_3810|M.thermoresistible__bu -----------------------VDVVGG---------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGVGGIGGAG----------STGAVGG-------VGGKG----IQGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GTGGVGGVGGVG----------ATGGAGG-------VGGKG----IQGGQ
MSMEG_0868|M.smegmatis_MC2_155 GTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGY
MUL_4367|M.ulcerans_Agy99 GAGGAGGEGLSG--------GFNTGAAGG-------IGGAGGAGGTGGDS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------NAGLAGN---------------------
MAV_4827|M.avium_104 ------------------------SAVGE---------------------
Mb0896c|M.bovis_AF2122/97 -----------------TPTGTADAGSTGTDQTLGGN-------------
Rv0872c|M.tuberculosis_H37Rv -----------------TPTGTADAGSTGTDQTLGGN-------------
MMAR_2492|M.marinum_M -----------------TPTGTAGTGASGT--PFSGD-------------
TH_3810|M.thermoresistible__bu -------------------NPDGGTPG-----------------------
Mflv_5091|M.gilvum_PYR-GCK G-------------LQGGKGGDGGAGGKGGDADSMGS-------------
Mvan_1264|M.vanbaalenii_PYR-1 G-------------LQGGQGGDGGTGGTGGDATSMGE-------------
MSMEG_0868|M.smegmatis_MC2_155 GPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIG
MUL_4367|M.ulcerans_Agy99 GGVGG-------VNGDGGAGGGGGRGGDGGSSTSTSG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------AGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104 --------------------EDAESPTVVIEKLFLPE-------------
Mb0896c|M.bovis_AF2122/97 -------AIGGNGGPGDAGDAMTSGG------------------------
Rv0872c|M.tuberculosis_H37Rv -------AIGGNGGPGDAGDAMTSGG------------------------
MMAR_2492|M.marinum_M -------GHAGSGHTGDNGAPGENGG------------------------
TH_3810|M.thermoresistible__bu -------AHGESHTPGVYTDRQ----------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGA
Mvan_1264|M.vanbaalenii_PYR-1 -----AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGG
MUL_4367|M.ulcerans_Agy99 -----VGGAGGAGGNGGNAGFGVSAG--------------GTGGSAGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------AGLAGNAGLAGNAGLAGN------------------------
MAV_4827|M.avium_104 -------------DSEPRRRPVLLVG------------------------
Mb0896c|M.bovis_AF2122/97 ----------------------AGGSGGNAVSTVNGDAVGGEGGKGGEG-
Rv0872c|M.tuberculosis_H37Rv ----------------------AGGSGGNAVSTVNGDAVGGEGGKGGEG-
MMAR_2492|M.marinum_M ----------------------TGGTGGEATGAGGIGGTGGNGGAAGSGG
TH_3810|M.thermoresistible__bu ---------------------------GEDGEDGTGTGIGGRGGNGG---
Mflv_5091|M.gilvum_PYR-GCK D----------------------GGTGGAGGAGGTGG-TGGAGGTGG---
Mvan_1264|M.vanbaalenii_PYR-1 N----------------------GGTGGNGGNGGTGG-TGGNGGTGG---
MSMEG_0868|M.smegmatis_MC2_155 NGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGAS
MUL_4367|M.ulcerans_Agy99 AGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGAGIDGGAGGAGGTGGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------AGLAGNAGLAGNAGLAGNAGLAGNAG-
MAV_4827|M.avium_104 --------------------------SGLAVVGISAVLALEIALAIGIR-
Mb0896c|M.bovis_AF2122/97 -------------AYGGAGGAGGSAASIG---NAAIGGNGGAGGNAQAPG
Rv0872c|M.tuberculosis_H37Rv -------------AYGGAGGAGGSAASIG---NAAIGGNGGAGGNAQAPG
MMAR_2492|M.marinum_M -------------ANGGDGGVGGAATDTFGF-DNNQGGNGGNGANGSGPG
TH_3810|M.thermoresistible__bu -------------SSSGTHPMAEDG--------EHVKALDGRPGLD---G
Mflv_5091|M.gilvum_PYR-GCK --------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTG
MSMEG_0868|M.smegmatis_MC2_155 VWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEG
MUL_4367|M.ulcerans_Agy99 --FPGGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGDSGTAGWAGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 --------------TTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPK
Mb0896c|M.bovis_AF2122/97 GVGGAG---------GEGGDAQVGTNSPSNAEA-------GNGGSGGNGF
Rv0872c|M.tuberculosis_H37Rv GVGGAG---------GEGGDAQVGTNSPSNAEA-------GNGGSGGNGF
MMAR_2492|M.marinum_M GAGGAG---------GDGGASTAG----GAATG-------GKGGHGGNGA
TH_3810|M.thermoresistible__bu GNGSHG---------GNGGHGGRGGFLGIGGSG-------GWGGHGGNGG
Mflv_5091|M.gilvum_PYR-GCK GTGGTG---------GTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTG---------GTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GTGGHG---------GDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGG
MUL_4367|M.ulcerans_Agy99 GAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGAGASGIGAGVAGGDGGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAG-------LAGNAGLAGNAAVAGNAAVA-------GNAAVAGNAA
MAV_4827|M.avium_104 ISVPEP---------VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAA
Mb0896c|M.bovis_AF2122/97 DS--------FASGGTGGAGGTG---------------GAGGRGG-----
Rv0872c|M.tuberculosis_H37Rv DS--------FASGGTGGAGGTG---------------GAGGRGG-----
MMAR_2492|M.marinum_M AS--------DLSGGNGGAAGAG---------------GNGGNAG-----
TH_3810|M.thermoresistible__bu D-----------TDADGGNGGDG---------------GNGGSAG-----
Mflv_5091|M.gilvum_PYR-GCK TG---------GTGGTGGTGGAG-----------DGTGGTGGTGG----T
Mvan_1264|M.vanbaalenii_PYR-1 TG---------GTGGTGGTGGAG-----------DGLGGTGGTGG----T
MSMEG_0868|M.smegmatis_MC2_155 NGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDAD
MUL_4367|M.ulcerans_Agy99 TGGAAGTGGAAGTGGTGGAAGAAG---------SAGDGGAGGAGG-AGDD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VG---------GVLNTGVSGAIG---------------GSSHVGG-----
MAV_4827|M.avium_104 PPVVPVPVVVPPVPVPVPVRIPVP--------------DPVSPPQ-----
Mb0896c|M.bovis_AF2122/97 ---------------------------LLIGDGGAGG-AGGVGGTG----
Rv0872c|M.tuberculosis_H37Rv ---------------------------LLIGDGGAGG-AGGVGGTG----
MMAR_2492|M.marinum_M ---------------------------LLVGNGGAGG-TGGVGGSG----
TH_3810|M.thermoresistible__bu ----------------------------RGGTGGLRGVFGINGGNG----
Mflv_5091|M.gilvum_PYR-GCK GGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG----
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG----
MSMEG_0868|M.smegmatis_MC2_155 GHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAAT
MUL_4367|M.ulcerans_Agy99 GSAGVVSGDPG-----------------TAGKAGGAGGAGGVGGNGVAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------AINESLGGSGSVGGSTAVG----
MAV_4827|M.avium_104 --------------------------LLAPPRLSVPQPVQPPVRVP----
Mb0896c|M.bovis_AF2122/97 -------------------GSGAPGGGG-AGGDGGAANTDSAG-------
Rv0872c|M.tuberculosis_H37Rv -------------------GSGAPGGGGGAGGDGGAANTDSAG-------
MMAR_2492|M.marinum_M -------------------GTGAAGGAGGTGGDGGTATGNFDP-------
TH_3810|M.thermoresistible__bu --------------------RAGLGGRGXXXXGGGVG-------------
Mflv_5091|M.gilvum_PYR-GCK -------------------GQGGTGGTGGQGGTGGTGGTGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGQGGTGGTGGTGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 IVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASG
MUL_4367|M.ulcerans_Agy99 -------------------GVNGSGGAGGAGGAGGTGGAGASG-------
MLBr_01183|M.leprae_Br4923 --------------------MPLFLNAEPQALTAAANTLEGLS-------
MAB_4284c|M.abscessus_ATCC_199 -------------------GGAHTGVGGGVSTGVGVGSHVGGG-------
MAV_4827|M.avium_104 -------------------QPPSPPQVGGTVPQSPPQHQTPPGE------
Mb0896c|M.bovis_AF2122/97 SSRKAFGGDGGVGG----DGASALGTGGEGGIGGQGGNGGAGGLLIGNGG
Rv0872c|M.tuberculosis_H37Rv SSRKAFGGDGGVGG----DGASALGTGGEGGIGGQGGNGGAGGLLIGNGG
MMAR_2492|M.marinum_M TGTAAQGQEGGDGG----SGADSTGIGGNGGNGGVGGNGGNGGRLLGLGG
TH_3810|M.thermoresistible__bu --AAVRSGNGVFSG----GGG-TPSAGFGVPTTIQFPAGSCTSRAVSREG
Mflv_5091|M.gilvum_PYR-GCK -GTGGAGGDGGLGG----LGG-FGGSGGTGGQGGLGGPGGSTGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGAGGDGGLGG----LGG-FGGVGGTGGQGGQGGPGGSTGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 IGAGGNGGDGIDGG----LGG-NGGDGVVNTTANAANPGSATGTATGGDG
MUL_4367|M.ulcerans_Agy99 VPASVDGGDGGAGG----AGG-AAGTGGSGGSAGNTGAGGAGGAGGAGGS
MLBr_01183|M.leprae_Br4923 --AATVASNAAAAQ----LTTEIAPPAADDVSILLAHFFSGHGRQYQAHA
MAB_4284c|M.abscessus_ATCC_199 -ISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGG
MAV_4827|M.avium_104 GTPPKPDGPGNYGG----GHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGG
. . . . .
Mb0896c|M.bovis_AF2122/97 -------------------------AGGVGGTAGAGG-------------
Rv0872c|M.tuberculosis_H37Rv -------------------------AGGVGGTAGAGG-------------
MMAR_2492|M.marinum_M -------------------------AGGDAGNGGVGG-------------
TH_3810|M.thermoresistible__bu ------------------------IMPSSRAASARAG-------------
Mflv_5091|M.gilvum_PYR-GCK --QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1 --QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGAT
MSMEG_0868|M.smegmatis_MC2_155 GKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGN
MUL_4367|M.ulcerans_Agy99 AASTGVNGDGGAGG----AGGVGGLGGDSAATAGGGGAGGDGGKGGAGGA
MLBr_01183|M.leprae_Br4923 S------------------------QGATNHQDLIQS-------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------SGSVGGSTAVGG-------------
MAV_4827|M.avium_104 ---------------------------GHVPTPGTGG-------------
.
Mb0896c|M.bovis_AF2122/97 ---------------TGGSGGAGGAGGAGGGGTN----------------
Rv0872c|M.tuberculosis_H37Rv ---------------TGGSGGAGGAGGAGGGGTN----------------
MMAR_2492|M.marinum_M ---------------TGGAGGAGGAGGHGGNATSGQL-------------
TH_3810|M.thermoresistible__bu --------------AACASSTSRSRRSFCCSRA-----------------
Mflv_5091|M.gilvum_PYR-GCK G------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------T
Mvan_1264|M.vanbaalenii_PYR-1 G------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------T
MSMEG_0868|M.smegmatis_MC2_155 GGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAI
MUL_4367|M.ulcerans_Agy99 G----VNGVGGGDGGKGGTGGAGGAGGAGSDGIIPSNGGLGGNGGNGGNG
MLBr_01183|M.leprae_Br4923 --------------LLTSSSAYAGTETANHDSL-----------------
MAB_4284c|M.abscessus_ATCC_199 ---------------GAHTGVGGGVNTGVGVGSHVGGG------------
MAV_4827|M.avium_104 --------------PGGTGGSGGGHVPTPGAGTPGGSG------------
.
Mb0896c|M.bovis_AF2122/97 -------SGPGAAFGGNGNTGGN-------------------------GG
Rv0872c|M.tuberculosis_H37Rv -------SGPGAAFGGNGNTGGN-------------------------GG
MMAR_2492|M.marinum_M ------SQGGNGGNGGGGGNGAD-------------------------GG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDG
Mvan_1264|M.vanbaalenii_PYR-1 TGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAG
MSMEG_0868|M.smegmatis_MC2_155 TDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGG
MUL_4367|M.ulcerans_Agy99 GQAFGDGVGGAGGIGGKGGNAAIGTIVINGGVGGAGG-----SGGLGGAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------ISESLGGSGSVGGSTAVG-------------------------G
MAV_4827|M.avium_104 -------GGHLPFPGAGSTPGGSG------------------------GG
Mb0896c|M.bovis_AF2122/97 NGGAPGALGGKGGSGGLIG-----------RAGSDGGVGAGGAGG-----
Rv0872c|M.tuberculosis_H37Rv NGGAPGALGGKGGSGGLIG-----------RAGSDGGVGAGGAGG-----
MMAR_2492|M.marinum_M DGGAAGLSGGNGGQGGLIG-----------VSGVDGAAGIGGRAG-----
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK DAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-
Mvan_1264|M.vanbaalenii_PYR-1 DPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-
MSMEG_0868|M.smegmatis_MC2_155 DGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEP
MUL_4367|M.ulcerans_Agy99 EDGVGGVG-CAGGAGGNGGRGDMLFTVGGSGGTGGDGGGGGSASGSGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTSAINDALGGSGSVGG---------------STAVGGGAHTSAINES
MAV_4827|M.avium_104 HLPTPGAGTPGGGLGGFGG--------------GHAPAPGGGLGG-----
Mb0896c|M.bovis_AF2122/97 ------AGGAGGTG-----GEGGTGGDGK---TTDGNPGMGGSPGSAGQP
Rv0872c|M.tuberculosis_H37Rv ------AGGAGGTG-----GEGGTGGDGK---TTDGNPGMGGSPGSAGQP
MMAR_2492|M.marinum_M ------AGGAGGAL-----GAGGAGGIAEGLIHVDGDAGLNGVAGTSGNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------GGAGGGG-----GAGGSGAGGAG--GAGGSGGSGGSGGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 -------GGAGGSG-----GAGGSGTGGAG--GAGGSGGSGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GPGGNGAGGAGGNG-----GTGGTTAGGSGNGGNGGNGGNGGADGTPGTA
MUL_4367|M.ulcerans_Agy99 SGGTGGVGGIGGDGKLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 MNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLP
MAV_4827|M.avium_104 -------------------GGGHAPAPGGGLGGFGGGHSGGGLGGLGGGH
Mb0896c|M.bovis_AF2122/97 GQPG--------------
Rv0872c|M.tuberculosis_H37Rv G-----------------
MMAR_2492|M.marinum_M GQHG--------------
TH_3810|M.thermoresistible__bu ------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGDSDD----------
Mvan_1264|M.vanbaalenii_PYR-1 GAAGDSD-----------
MSMEG_0868|M.smegmatis_MC2_155 GTTGANNP----------
MUL_4367|M.ulcerans_Agy99 AGGAPSDKGINGEPGNPG
MLBr_01183|M.leprae_Br4923 ------------------
MAB_4284c|M.abscessus_ATCC_199 GAEHH-------------
MAV_4827|M.avium_104 K-----------------