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PEYFSDTSRWTCSPEHVDLDIPRRFTRRVRLAAQPQHVTLDLGDAAVIVVDMQNDFCHERGWLASQGVDV RGGAGLKTPINAMLDGFRGAQVPIIWLNWGTRSDRANLPPNVLHAYDGEGTGGGIGESVSLLSNAVLTAN SWGAAILDGLVVDDIDIHVNKHRMSGFWDTELDSILRNLGVRHLFLCGVNVDQCVYATLIDAACAGYDCL LITDASATTSPSYCTEATIYNVRQCFGFTCDTAAIRASLHAPTEPHGVCGTCQPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3790 | - | - | 100% (266) | isochorismatase family protein |
| M. marinum M | MMAR_2657 | - | 3e-09 | 29.08% (141) | isochorismatase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4334 | - | 6e-07 | 27.92% (154) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3431c | - | 2e-15 | 29.83% (181) | isochorismatase hydrolase |
| M. avium 104 | MAV_5193 | - | 1e-05 | 23.86% (197) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4379 | - | 5e-07 | 25.53% (188) | isochorismatase hydrolase |
| M. thermoresistible (build 8) | TH_0553 | - | 1e-05 | 33.33% (99) | isochorismatase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | 2e-17 | 27.35% (223) | isochorismatase hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4334|M.gilvum_PYR-GCK -------------------------------MRIP-----LAELVAPGHT
TH_0553|M.thermoresistible__bu ---------------------------MFILMPQPR----LSDLIDPRST
MAB_3431c|M.abscessus_ATCC_199 ---------------------------MTGQVDAQPYPWPFDGPVDPGRT
Mvan_3053|M.vanbaalenii_PYR-1 ---------------------------MNHTVDVPAEPSSF--PLVAGRT
MMAR_3790|M.marinum_M ----MPEYFSDTSRWTCSPEHVDLDIPRRFTRRVRLAAQPQHVTLDLGDA
MSMEG_4379|M.smegmatis_MC2_155 ---------------------------MVTDQSAAMS-------FTAGTT
MAV_5193|M.avium_104 MLSADHRFQQTMTVRFGRRGRVPITGWVQSRRGVGMAGEDHYTRPCADSA
:
Mflv_4334|M.gilvum_PYR-GCK AVVTQECQEAVVGTNAGLAALADAARG--EALPNISRLLPVARRAGVDVV
TH_0553|M.thermoresistible__bu ALVTQECQGGVIGPQAGLPHLAAEAQR--EAIPNIGKLLDAARSAGVTVV
MAB_3431c|M.abscessus_ATCC_199 AVLCIDWQVDFCGRGGYVDTMGYDLSLTRAGLEPTARVLAAARAVGMTII
Mvan_3053|M.vanbaalenii_PYR-1 ALIVIDMQRDFLLPGGFGESLGNDVGRLLKVVPPLASLIAAARAAGVMVV
MMAR_3790|M.marinum_M AVIVVDMQNDFCHERGWLASQGVDVRGGAGLKTPINAMLDGFRGAQVPII
MSMEG_4379|M.smegmatis_MC2_155 GLVVIDPYNDFISEGGKVWDLLRGVAEAIGCVPHMIEMTEAARASGIPVF
MAV_5193|M.avium_104 ALVLIDVQRDFYADDAPMR-----VEGTSAALGAMAELARAFRRRELPIV
.:: : . . : * : :.
Mflv_4334|M.gilvum_PYR-GCK HCLVQRRADG--------RGANHNAKLFTVGAS-----GVDITPDSPGTQ
TH_0553|M.thermoresistible__bu HCLIQRRPDG--------RGSNTNARLFAAATSF----DADLTPGTPGAS
MAB_3431c|M.abscessus_ATCC_199 HTREGHRPDLSDLPANKRWRSARIGAEIGVAGPC----GRILVKGEPGWE
Mvan_3053|M.vanbaalenii_PYR-1 HTREGHQPDLSDCPPAKLNRGTPS-KRIGDPGRY----GRILIRGEYGHD
MMAR_3790|M.marinum_M WLNWGTRSDRANLPPNVLHAYDGEGTGGGIGESVSLLSNAVLTANSWGAA
MSMEG_4379|M.smegmatis_MC2_155 YALHRRYRPGD-------YESWRYVAPIQRAAWS----RRTFEYGSWGGE
MAV_5193|M.avium_104 HVVRLYRADGS-------NADPVRRRFIEDGAR-------VAEPGSPGSQ
. *
Mflv_4334|M.gilvum_PYR-GCK LVPEIDVQPSDL-----------------VLRRWHGLGPMGGTDLDAILR
TH_0553|M.thermoresistible__bu VLPEFGPEPEDL-----------------VLTRMHGVGPMTGTDLDSVLR
MAB_3431c|M.abscessus_ATCC_199 IVPEVAPLPGEP-----------------IID-KPGKGAFYATDLDLVLR
Mvan_3053|M.vanbaalenii_PYR-1 IIDELAPIDGEI-----------------VID-KPGKGAFYATSLSDVLT
MMAR_3790|M.marinum_M ILDGLVVDDIDI-----------------HVN-KHRMSGFWDTELDSILR
MSMEG_4379|M.smegmatis_MC2_155 IHPDLAPRPGDI-----------------VAQEHWCSSGFANTDLDMLLK
MAV_5193|M.avium_104 IAPELLPKAVELDHQLLLSGGFQQIGPAEHVMYKPRWGAFYGTKLEQHLR
: . : . : *.*. *
Mflv_4334|M.gilvum_PYR-GCK NLGVTTIVAVGVSVNVAILNLVMDAVNAGYRVVLPRDGVAGIPAEY-ATA
TH_0553|M.thermoresistible__bu NLGIETIVGVGVSVNIAIPNFVMDAVNRGYRFVLPRDAVAGYPREY-AEA
MAB_3431c|M.abscessus_ATCC_199 TRGIRYIVLTGITTDVCVHTTMREANDRGFECLILSDCTGATDAGN-HAA
Mvan_3053|M.vanbaalenii_PYR-1 EAGITQLLITGVTTEVCVHTTTREANDRGYQCLVVSDCVGSYFPEF-QRV
MMAR_3790|M.marinum_M NLGVRHLFLCGVNVDQCVYATLIDAACAGYDCLLITDASATTSPSYCTEA
MSMEG_4379|M.smegmatis_MC2_155 RHGIHQIIVVGLIAHTCVEATVRYGAELGYQVTLVRDATADYSVEEMRAA
MAV_5193|M.avium_104 ESGTDTLVFAGCNFPNCPRTSIYEASERDFRIVLVTDAISGLYDRG----
* :. * . . .: : * .
Mflv_4334|M.gilvum_PYR-GCK VIDNTLSLLATLTITDDLISAWAATC------------
TH_0553|M.thermoresistible__bu VIDNSLALLATVTSTDEVTGVWNGATDRRLDVDTR---
MAB_3431c|M.abscessus_ATCC_199 ALKMVTMQGGVFGAVADSNQLLGAL-------------
Mvan_3053|M.vanbaalenii_PYR-1 GLEMIKAQGGIFGWVADTSSVIPALARLSSIPA-----
MMAR_3790|M.marinum_M TIYNVRQCFGFTCDTAAIRASLHAPTEPHGVCGTCQPE
MSMEG_4379|M.smegmatis_MC2_155 LEVTLPNYASAIASTDEVIHAIAGMR------------
MAV_5193|M.avium_104 -AQECRAIGVAVRDTAQTLDWLGG--------------
. .