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M. marinum M MMAR_2656 (-)

annotation: PE-PGRS family protein, PE_PGRS50
coordinates: 3235425 - 3241781
length: 2118
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Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2656--100% (2118)PE-PGRS family protein, PE_PGRS50
M. marinum MMMAR_3763-0.063.32% (1843) PE-PGRS family protein
M. marinum MMMAR_0806-0.053.85% (2208) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3541PE_PGRS550.050.37% (2019) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-17745.43% (843) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.049.09% (1874) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1032.97% (91) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-5e-5034.41% (465) hypothetical protein MAB_4284c
M. avium 104MAV_4827-3e-2346.79% (156) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17440.73% (1063) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-3e-4439.93% (303) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.050.26% (1136) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-17848.07% (776) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv3508|M.tuberculosis_H37Rv         -MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSA
MUL_4367|M.ulcerans_Agy99           -MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSA
MMAR_2656|M.marinum_M               -MSLVTVSPELVAGAASDLARIGSSLGAANAAAAGPTTTVLSAAADEVSV
Mb3541|M.bovis_AF2122/97            -MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVA
MLBr_01183|M.leprae_Br4923          MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_4827|M.avium_104                -MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPD
                                                                                      

Rv3508|M.tuberculosis_H37Rv         RIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA------
MUL_4367|M.ulcerans_Agy99           AIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNM---W
MMAR_2656|M.marinum_M               AIATLFGTHAAEYQSLSARMAAFHEQFVQTLTSGAGIYVSTEATNASFIS
Mb3541|M.bovis_AF2122/97            RIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATN-----
Mflv_5091|M.gilvum_PYR-GCK          --MVTFGGGA---TPTPTSLGAAAVDLSGTSCG-----------------
Mvan_1264|M.vanbaalenii_PYR-1       WYVVSFGGSG---APTPNNLAASLVDLSGTSCG-----------------
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTT----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQP---------------
MLBr_01183|M.leprae_Br4923          LLAHFFSGHGRQYQAHASQGATNHQDLIQ---------------------
MAV_4827|M.avium_104                RVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR-------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGN-
MUL_4367|M.ulcerans_Agy99           PLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGN-
MMAR_2656|M.marinum_M               ALQLAEQNALNAINAPTQSWLGRPLIGNGVDATPGSGQAGGAGGLLWGN-
Mb3541|M.bovis_AF2122/97            ----VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGDGGLLFGS-
Mflv_5091|M.gilvum_PYR-GCK          ------------------------LICNGQD------GTGQNGGILFGN-
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------LICNGQD------GTGQNGGILFGN-
MSMEG_0868|M.smegmatis_MC2_155      -----DQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------DGPSILSPSLLSPRDNDFLSHN-
MLBr_01183|M.leprae_Br4923          -------------------------------------------SLLTSS-
MAV_4827|M.avium_104                ---------------------------------DALAARRIDNVMLVSAF
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGS----GGGTGGAGGAGG
MUL_4367|M.ulcerans_Agy99           GGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-----------------
MMAR_2656|M.marinum_M               GGAGG-SGAAGQSGGAGGSAGLFGNGGAGGAGGISAAGNGGSGGVGGRGG
Mb3541|M.bovis_AF2122/97            GGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGT-----GAPGGNGGNAG
Mflv_5091|M.gilvum_PYR-GCK          GGSGWNSDVVGMDGGNGGNGGLFG--GNGGNGGN----------------
Mvan_1264|M.vanbaalenii_PYR-1       GGSGWNSEIAGVSGGNGGNAGLFG--GNGGNGGN----------------
MSMEG_0868|M.smegmatis_MC2_155      LGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----DTDFASHNPIASGNQVMSPSGNVDSFNR-----------------
MLBr_01183|M.leprae_Br4923          ------SAYAGTETANHDSL------------------------------
MAV_4827|M.avium_104                LAAAALAQNVGGAMGYERTAVLLVEPDTATLAVV----------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         WLFGVGGAGGVGGAGGGTGGAGGPGG--LIWGGGGAGGVGGAGGGTGGAG
MUL_4367|M.ulcerans_Agy99           ----VGAAG----MTGGSGGAGGGGG--WLWGAGGSGGAAGAGG------
MMAR_2656|M.marinum_M               LVYGSGGAGGAGGQGALSGGAGGAGGGAWLWGAGGAGGSGGEGLASAGGV
Mb3541|M.bovis_AF2122/97            WLYGRGGVG---GAGGIGGGTGGAGGHAWLFGHGGTGGIGGGPGGNGG--
Mflv_5091|M.gilvum_PYR-GCK          ------------GLGGGNGGNGGNAGAFALFGNGGNGGNG----------
Mvan_1264|M.vanbaalenii_PYR-1       ------------GLGSGDGGNGGDAGLFSLFGRGGNGGNG----------
MSMEG_0868|M.smegmatis_MC2_155      TVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISG---
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------GPLLDLSFGDLQFGNRDTTAIG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------ETSDGSIPDVYKQQIR--------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GRAELLFGAGGAGGAGTDGGPGATGGTGGHGGVGGDGG---WLAPGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------SGGSGG---WLWG-----
MMAR_2656|M.marinum_M               GGAG-----GNAGLIGTGGLGGAGGVGGQNGGAGGDGGNAPLLGRGGTGG
Mb3541|M.bovis_AF2122/97            ------------WLLGNGGHGGAGGIGGGSGGAGGNGG--WLLGNGGIGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AG-----GQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQ
MUL_4367|M.ulcerans_Agy99           --------------------------NAGQTAGAG---------------
MMAR_2656|M.marinum_M               VGGASDGGNGGAGGDGGVGGGLFGSGGAGGSGGAGGVLGTGGDGGSGGAA
Mb3541|M.bovis_AF2122/97            AG-------GTGGGAGGTGGNAAWLLGGGGTGGAGGIG--GGNGGHGGNG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGLGGAGGQGGTGGAGGDGVLGGVGGTGGK-GGVGGVAGLGGAGGAAGQL
MUL_4367|M.ulcerans_Agy99           --VGGAGGAGGAGDAGDQGVSG----------------------------
MMAR_2656|M.marinum_M               AGLWGAGGSGGAGGNGADGISGGIGESGGD-G---GNAGNGGAGGRGGRL
Mb3541|M.bovis_AF2122/97            GWLLGNGGNGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTG
Mflv_5091|M.gilvum_PYR-GCK          ----GVGVVGATGAVGAPGVAG----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----GVGIAGATGAVGAPGVAG----------------------------
MSMEG_0868|M.smegmatis_MC2_155      -QYLIGNGINGTADNPNGGTGG----------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------DGAVAVGGSNSGPIAS----------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----AESYGDAAGQLSAMVAG----------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         FSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLTGGTGF-AGGAGG
MUL_4367|M.ulcerans_Agy99           --------------------------------VAPGEAGAVGF-AGGAGG
MMAR_2656|M.marinum_M               IGAGGAGGFGGVGGLGGAGGAGANG----IVAGSAGDGGGNGG-SGGAGG
Mb3541|M.bovis_AF2122/97            TAGGGSGGTGGDGGTGGRGGLLMGAGAG--GHGGTGGAGGAGVDGGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ------------------------------------ATGATGVTSGVVGG
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------ATGATGVTSNVTGG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------LLFGDGGHGYDGSAAGL
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VGGQGGNA-----IAG-GINGSGGAGGTGGQGG-----AGGMGGSGADNA
MUL_4367|M.ulcerans_Agy99           AGGAGGNG-----VGG-GVNGAGGAGGAGGVGG-----GGGAGASGVG--
MMAR_2656|M.marinum_M               VGGDGGKGGLIRFLGGRGAGGSGGEGGAGGAAG-----DGGDGAAGSFLT
Mb3541|M.bovis_AF2122/97            AGGAGGNGGAG--GQAALLFGRGGTGGAGGYGG-----DGGGGGDGFDGT
Mflv_5091|M.gilvum_PYR-GCK          NGED--------------AVGYGATGAAGAAGA-----AGAAG-------
Mvan_1264|M.vanbaalenii_PYR-1       NGAD--------------AVGYGATGAAGAAGA-----AGAAG-------
MSMEG_0868|M.smegmatis_MC2_155      AGGNGGNAGLFGNGGNGGVGWAGLDGGNGGSGGLLMGIGGAGGAGGVGAD
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------GQGSTAVNGDVRD-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------LEKLESLPGGLLLVGS------GVDVAPLKQVL
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -SGIGADGGAGGTGGNAGAGGAGG--------------------------
MUL_4367|M.ulcerans_Agy99           ---AGVAGGDGGTGGAGGAAGVGG--------------------------
MMAR_2656|M.marinum_M               GTGAGGAGGQGGDPGLGGAGGAGGRGSVPGSHGVTGQSPTSGGDGGNGGR
Mb3541|M.bovis_AF2122/97            MAGLGGTGGSGGTGGDGGAPGNGG--------------------------
Mflv_5091|M.gilvum_PYR-GCK          ---AAGAVGSAGAAGEAGETGTWG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---KAGAVGSAGTAGSAGAPGVWG--------------------------
MSMEG_0868|M.smegmatis_MC2_155      GTSAHVDGGTGGTGGTGGGTGGTG--------------------------
TH_3810|M.thermoresistible__bu      -----VD----GDGGSGGRTG-----------------------------
MAB_4284c|M.abscessus_ATCC_199      --SNIINADHGSNVGVDQSQTRVG--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QTTTFLDVSVAEEPETALARG-----------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---------AAGTGGTGGVVGAAGKAGIGGTGGQ----------------
MUL_4367|M.ulcerans_Agy99           ---------AAGTGGTG------GAAGVAGTGGD----------------
MMAR_2656|M.marinum_M               GADAIDPATTAGAGGVGGDGGRYGNGGVGGAGGDGYRGYDGMSVVGGDGT
Mb3541|M.bovis_AF2122/97            ---------AGGAGQLLSHSGVAGASGKGGAGGT----------------
Mflv_5091|M.gilvum_PYR-GCK          ------------------------NAGLPGKAGD----------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------NAGLPGAAGA----------------
MSMEG_0868|M.smegmatis_MC2_155      -------GIGGTGGGLFGLLGHSGSTGAAGAAGN----------------
TH_3810|M.thermoresistible__bu      ---------------LFSKLSR----------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------GDYTN----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -GGAGGAGSAGTDATAT-GATGGTGFSGGAGGAGGAGGNTGVGG------
MUL_4367|M.ulcerans_Agy99           -GGDGGAGGAGSDASLA-GQAG---FAGGSGGAGGVGGSAGAGG------
MMAR_2656|M.marinum_M               VGGDGGAGGAGGAGGMG-GALAGHGGAGGAGGDGGTGGIGGDGGRGVDGT
Mb3541|M.bovis_AF2122/97            -GGNGGAGSAGADAPAGSGAMGSTGFAGGAGGDGGNGGGSGASQG-----
Mflv_5091|M.gilvum_PYR-GCK          ---AGGAGAVGAAGAAG--TVG----TAGATGGTGTGANGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1       ---AGGAGAIGTAGVAG--AAG----TAGATGGTGVGGNGGAGQ------
MSMEG_0868|M.smegmatis_MC2_155      -GGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGP-----
TH_3810|M.thermoresistible__bu      -GGDGGDGGLG---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGS------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----AALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVP-----
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -------TNGSGGQGGTGGAGGAGGAGGVGADN--PTGIGGTGGTGGKGG
MUL_4367|M.ulcerans_Agy99           -------VNGSGGDGGAGAAGGAGGASAT---------VAGSGGVGGDGG
MMAR_2656|M.marinum_M               DLSLDGTDGGSGGMGGVGGAGGDGGAGGLAQAAGFSDGIRGVGGAGGDGG
Mb3541|M.bovis_AF2122/97            -------NGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK          -------VGGVGGTGAAGAAGGAGGLGET----------GTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1       -------AGGIGGTGAAGAAGQAGTAGET----------GVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155      -------GKGGGGGGGGGGAILIGANGGTVDGH----AIGGNGGNGGNGS
TH_3810|M.thermoresistible__bu      ---------GNGGHGGGTGIISLLS-------------LAGNGGNGGNGY
MAB_4284c|M.abscessus_ATCC_199      ---------GNTTNTEIGSHNQANIGTSTS--------AGGSAAVGGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------VDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPV
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AGGAGGQGGSSG-----AGGTNGSGGAGGTGGQGGAGGAGGAGADN----
MUL_4367|M.ulcerans_Agy99           AGGAAG--------------------------------------------
MMAR_2656|M.marinum_M               AGGGAGDGGDGANAPAASGLAGGSGGHGGDPGVGGAGGAGGTGSVTGAHG
Mb3541|M.bovis_AF2122/97            NAGAGG-----------TGFTQGADGNAGNGGDGGVGGNGGNGADN----
Mflv_5091|M.gilvum_PYR-GCK          QGTAGG--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       QGTEGG--------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TTAAGGNGGTGG--------------------------------------
TH_3810|M.thermoresistible__bu      RTTDNN--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAG--------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LLVGSG--------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -------PTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAG-
MUL_4367|M.ulcerans_Agy99           ------------------------------------------GGVGAAS-
MMAR_2656|M.marinum_M               TEGLTQTTGGNGGDGGDGANASTVGASGGAGGAGGDGGRYGNGGVGGAGG
Mb3541|M.bovis_AF2122/97            ------------------TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG-
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------TGGVGGIG-
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------TGGVGGVG-
MSMEG_0868|M.smegmatis_MC2_155      ------------------------TGRVIAEGTGSTAEGTATGGDGGHS-
TH_3810|M.thermoresistible__bu      ---------------------------------------ALDGGHGGN--
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------LAGNAGLAG-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         -----------IGGTGGTGGVGGAGGAGAAAAAG-----SSATGGAGFAG
MUL_4367|M.ulcerans_Agy99           -----------LGGDGGHAGAGGAGGEGLSGGFN-----TGAAGGIGGAG
MMAR_2656|M.marinum_M               DGYRGYDGMSVVGGDGTVGGDGGAGGAGGAGGMGGALAGHGGAGGAGGDG
Mb3541|M.bovis_AF2122/97            -----------TGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDG
Mflv_5091|M.gilvum_PYR-GCK          -------------GAGSTGAVGGVGGKGIQGGQG-------LQGGKGGDG
Mvan_1264|M.vanbaalenii_PYR-1       -------------GVGATGGAGGVGGKGIQGGQG-------LQGGQGGDG
MSMEG_0868|M.smegmatis_MC2_155      ----------TGTGIGGNGGIGSVYAYGNNGAVS-----GTATGGRGGDG
TH_3810|M.thermoresistible__bu      ---------------GGNVGFFSLFNLG-------------GAGGWGGSG
MAB_4284c|M.abscessus_ATCC_199      -------------NAGLAGNAGLAGNAGLAGNAG--------LAGNAGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------LAVVGISAVLALEIALAIGIRTTGTVALQPTPNQH
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GAGGEGGAGGNSGVGGTN--------GSGGAGGAGGKGGTGGAGGSGADN
MUL_4367|M.ulcerans_Agy99           GAGGTGGDSG--GVGGVN--------GDGGAGGGGGRGGDGGSSTS----
MMAR_2656|M.marinum_M               GTGGIGGDGGR-GVDGTDLSLDGTDGGSGGMGGVGGAGGDGGAGGLAQAA
Mb3541|M.bovis_AF2122/97            GQGGTGGTGGNAGAGGTG-----FTQGADGNAGNGGDGGVGGNGGNGADN
Mflv_5091|M.gilvum_PYR-GCK          GAGGKGGDADSMGSAGATG-------GKGGNGGNGGRGGLFGKGGN----
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGDATSMGEAGATG-------GKGGNGGNGGRGSLFGRGGN----
MSMEG_0868|M.smegmatis_MC2_155      IDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQ
TH_3810|M.thermoresistible__bu      VDG---------------------------------VDVVGGN-------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAG-----------NAGLAGNAGLAGN-------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LIVPTEQAPAPPPVQASAP-----------QPKISVPEPVAAPKPLS---
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---------------PTGAGFAGGAGGTGGAAGAGGAGG--ATGTGGTGG
MUL_4367|M.ulcerans_Agy99           ---------------TSGVGGAGGAGGNGGNAGFGVSAG--GTG------
MMAR_2656|M.marinum_M               G----------FSDGIRGVGGAGGDGGAGGGAGDGGDGANAPAASGLAGG
Mb3541|M.bovis_AF2122/97            -------------TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQG
Mflv_5091|M.gilvum_PYR-GCK          ----------------AGNGADGGTGGAGGAGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------AGNGGNGGTGGNGGNGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNT
TH_3810|M.thermoresistible__bu      -----------------------PDGGTPG--------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------AGLAGNAGLAGNAGLAG-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------PPVAAPLPAAPPPAAPPLP---------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         VVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGG----
MUL_4367|M.ulcerans_Agy99           -----GSAGDGGAGG-----------------------------------
MMAR_2656|M.marinum_M               SGGHGGDPGVGGAGGAGGTGSVTGAHGTEGLTQTTGGNGGDGGDGANAST
Mb3541|M.bovis_AF2122/97            NGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGNAG----
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGAASANGAVGGNGGFTNI--------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ---SAGAGGINGAGGAGGNGGDGGDGATGA--------AGLGDNGGVGGD
MUL_4367|M.ulcerans_Agy99           -----GAGGVDGVGGASGNGGAAGAGGAGG--------SGIG----AGID
MMAR_2656|M.marinum_M               VGASGGAGGAGGDGGRYGNGGVGGAGGDGYRGYD--GMSVVGGDGTVGGD
Mb3541|M.bovis_AF2122/97            ---AGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTTTAAAGTTGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          -----GTGGAGGTGGTGGTGGIGGAGSTGG----------------TGGT
Mvan_1264|M.vanbaalenii_PYR-1       -----GTGGNGGTGGTGGTGGIGGAGSTGG----------------TGGT
MSMEG_0868|M.smegmatis_MC2_155      ---AAIHGSITDSSATSGHGGAAQGGNGGN---------------GGNGW
TH_3810|M.thermoresistible__bu      -----AHG------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------------NAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------------EAPPI
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDN------
MUL_4367|M.ulcerans_Agy99           GGAGGAGGTGGAAGF-----PGGGGTTGAWGTGGAGGAGGAG--------
MMAR_2656|M.marinum_M               GGAGGAGGAGGMGGALAG-HGGAGGAGGDGGTGGIGGDGGRGVDGTDLSL
Mb3541|M.bovis_AF2122/97            GGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTGGKGGTGGDGALAG----
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGG-----------TGGTGGTGGTGGTGGKGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGG-----------TGGTGGTGGTGGTGGKGGTG--------
MSMEG_0868|M.smegmatis_MC2_155      VQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTG--GATGGRG--------
TH_3810|M.thermoresistible__bu      -ESHTP----GVYTDRQ-------GEDGEDGTG--TGIGGRG--------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAG-----------LAGNAGLAGNAGLAGNAAVA--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLS--------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         ----NFNGGQGGAGGQGGQGGLGGASTTS--------INANGGAGGNGGT
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2656|M.marinum_M               DGTDGGSGGMGGVGGAGGDGGAGGLAQAAGFSDGIRGVGGAGGDGGAGGG
Mb3541|M.bovis_AF2122/97            -----SSGGAGGKGGNGGDAGKAGTGSAPG-------TAGTGGDGGKGGN
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFG--GAAGKAGGGGNG
MUL_4367|M.ulcerans_Agy99           ------------GAGDHGGVGVNPGDSGTAG-------------------
MMAR_2656|M.marinum_M               AGDGGDGANAAAGSGAVGGKGGDGGDPGVGGAGGAG--GTGSVTGAHGTE
Mb3541|M.bovis_AF2122/97            GGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGAGGAGGNG
Mflv_5091|M.gilvum_PYR-GCK          ------------GTGGAGGTGGDGGTGGTGG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------GTGGDGGTGGTGGTGGTGG-------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------GDGAGASVWKANGQHSTGQTD-----------------
TH_3810|M.thermoresistible__bu      ------------GNGG-----SSSGTHPMAE-------------------
MAB_4284c|M.abscessus_ATCC_199      ------------GNAAVAGNAAVAGNAAVGG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------VPQPVQPPVRVPQPPSPPQ-------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGG
MUL_4367|M.ulcerans_Agy99           -------------------WAGGAGGAGGAGGSAAFNGVNGAGGAGGNGG
MMAR_2656|M.marinum_M               GLTQTTGGNGGDGGNGGSGTTGTTGSKGGAGGAGGDGGRYGNGGNGGTGG
Mb3541|M.bovis_AF2122/97            GKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAGATPGANGIAGNGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------TGGTGGTGGTGGTGGAG--DGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------TGGTGGTGGTGGTGGAG--DGLGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      --------------------TGGNGGRGGDGGTFVNAGANGNGGAGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         DGGDGATGAA-----------GLGDNGGVGGDGGAGGAAGNGGNAGVGLT
MUL_4367|M.ulcerans_Agy99           AGGGGGAGAS-----------GIG-AGVAGGDGGTGGTGG----------
MMAR_2656|M.marinum_M               TGSTGTAGSSDVMGAN----GGAGGSGWAGGDGGAGGMGG----TLAGHG
Mb3541|M.bovis_AF2122/97            DGGDGAAGAVGISGATGAGDGGHGGTGGAGGNGGTGGAGG-----SGIDG
Mflv_5091|M.gilvum_PYR-GCK          TGGQG----------------GQGGQGGTGGTGGQGGLGG----------
Mvan_1264|M.vanbaalenii_PYR-1       TGGFG----------------GQGGQGGTGGTGGQGGLGG----------
MSMEG_0868|M.smegmatis_MC2_155      VSEGEGGTG------------GHGGDGGRGGDGALGGNGG-------TGG
TH_3810|M.thermoresistible__bu      -----------------------DGEHVKALDGRPGLDG-----------
MAB_4284c|M.abscessus_ATCC_199      ----------------------VLNTGVSGAIGGSSHVGG---------A
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------VGGTVPQSPPQHQTP----------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         AKAGDGGAAGNGGNGGAGG-----------AGGAGDNNFNGGQGGAGGQG
MUL_4367|M.ulcerans_Agy99           -AAGTGGAAGTGGTGGAAG-----------AAGS----------------
MMAR_2656|M.marinum_M               GDGGDGGSGGTGGTGGRGGNGFNGSTKAGLNGGDAGDGGAGGVGGAGGNG
Mb3541|M.bovis_AF2122/97            VGGGTGGTGGNGGNGAIGG----------AGGDAGGSGNSGGNGGTGGKG
Mflv_5091|M.gilvum_PYR-GCK          -GGGTGGQGGTGGTGGQGG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -VGGTGGTGGTGGTGGQGG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VGLGNGGKGGNGGNGGNGGT------------------------------
TH_3810|M.thermoresistible__bu      ---GNGSHGGNGGHGGRGG-------------------------------
MAB_4284c|M.abscessus_ATCC_199      INESLGGSGSVGGSTAVGG-------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --PGEGTPPKPDGPGNYGG-------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GQGGLGGAS--TTSINANGGAGGNGGTGGKGGAGGAGT---LGVGGSGGT
MUL_4367|M.ulcerans_Agy99           ---------------------AGDGGAGGAGGAGDDGS---AGVVS----
MMAR_2656|M.marinum_M               GAAGLAQAAGFSDGIQGAGGAGGDGGAGGGAGDGGDGANAAAGSGAVGGN
Mb3541|M.bovis_AF2122/97            GNAGAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGN
Mflv_5091|M.gilvum_PYR-GCK          -----------------------TGGTGGTGGTG----------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------TGGTGGTGGTG----------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------YVDPSHTGAGGNGGNGGAGRIRVNNGTATGTA---
TH_3810|M.thermoresistible__bu      --------------------FLGIGGSGGWG-------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------GAHTGVGGGVSTG----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------GHVPTP----------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDG
MUL_4367|M.ulcerans_Agy99           ----GDPG---------TAGKAGGAG------------------------
MMAR_2656|M.marinum_M               GGDGGDPGLGGGGGAGGTGATTGAHGADGLSPTTGGNGGKGGNGGSGAIG
Mb3541|M.bovis_AF2122/97            GGTGGRGGSGGAGG-DGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GQGGQGGAGGSAGAGG-INGAGGAGGTGGAGGDGAPATLIG--GPDGGDG
MUL_4367|M.ulcerans_Agy99           ---GAGGVGGNGVAGG-VNGSGGAGGAG----------------------
MMAR_2656|M.marinum_M               VAGGAGGAGGDGGLYG-DGGDGGSGGNGGAGKAGAAGVSAGSNGEAGGQA
Mb3541|M.bovis_AF2122/97            GNGGQGGQGGSGGAGG-AAGAGGAGGGANGTAGNGGQGGAGGTGGAGAAS
Mflv_5091|M.gilvum_PYR-GCK          ---GTGGAGGDGGLGG-LGGFGGSGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGAGGDGGLGG-LGGFGGVGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155      -TGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASG---------
TH_3810|M.thermoresistible__bu      ---GHGGNGGDTDADGGNGGDGGNGG------------------------
MAB_4284c|M.abscessus_ATCC_199      --VGVGSHVGGGISES-LGGSGSVGGST----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---GAGGSGGSGGGHVPTPGAGGSGGSG----------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAG
MUL_4367|M.ulcerans_Agy99           --------------------------------------------GAGGTG
MMAR_2656|M.marinum_M               GAGGVGGAGGNGGANAGNGGTGGNGGDGGVG-GTGGAGKVGTTGPAGGAG
Mb3541|M.bovis_AF2122/97            SATNGGSGGAGGTGGAGGTGGAGGDGVGGAGGGNGGHGGDAGDGGNGANG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------GQGGLG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------GQGGQG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------TATGGDG
TH_3810|M.thermoresistible__bu      ---------------------------------------------SAGRG
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------AVGGGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGA
MUL_4367|M.ulcerans_Agy99           GAGASGVP-----------------------------ASVDGGDGGAGGA
MMAR_2656|M.marinum_M               GEGGDGGKGGTGGRGGNGGAGG-----TAQAAGYSDGSQGVGGDGGAGGT
Mb3541|M.bovis_AF2122/97            NNRSSGSFLAAGGTGGAAGDGG-----QGGQGGAGGGAGGQGGAGGAGGT
Mflv_5091|M.gilvum_PYR-GCK          GPG--------------------------------------GSTGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1       GPG--------------------------------------GSTGGAGGA
MSMEG_0868|M.smegmatis_MC2_155      GNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGN
TH_3810|M.thermoresistible__bu      GTGGLRGVF--------------------------------GINGGNGR-
MAB_4284c|M.abscessus_ATCC_199      HTGVGGG---------------------------------VSTGVGVGSH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------GGHVPTPGT
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAG----IGGAGG
MUL_4367|M.ulcerans_Agy99           GG-----------AAGTGGSG------------GSAGNTG----AGGAGG
MMAR_2656|M.marinum_M               GG--------TAGNGGKGGAGTWAVNNGIGGKGGNGGNAG----TGGTGG
Mb3541|M.bovis_AF2122/97            GGNGGNITGGTAGTAGAAGNGGAAGKGGAGGQGGTGGGTGGQGGAGGDGG
Mflv_5091|M.gilvum_PYR-GCK          GG-----------QAGTAGKG------------GLFGGSG------SAGK
Mvan_1264|M.vanbaalenii_PYR-1       GG-----------QAGVAGKG------------GLFGGSG------SAGT
MSMEG_0868|M.smegmatis_MC2_155      GG-----------QGTIEANGPSAVASGIGAGGNGGDGID-----GGLGG
TH_3810|M.thermoresistible__bu      ---------------------------------------------AGLGG
MAB_4284c|M.abscessus_ATCC_199      VG----------------------------------GGIS-----ESLGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GG------------------------------------------PGGTGG
                                                                                      

Rv3508|M.tuberculosis_H37Rv         RGGDG---GAGDSGALSQDGNGFAGGQGGQ-----GGVGGNAGAGGINGA
MUL_4367|M.ulcerans_Agy99           AGGAG---GSAASTGVNGDG----------------------------GA
MMAR_2656|M.marinum_M               SFGTGSQIGNHGSTGHLGDGGDGGTGGAGVNATAPGQDGAAGGVGGNGGI
Mb3541|M.bovis_AF2122/97            AGGTGGDRTVGGGTVPAGSGGQGGNAGGGGAGGQGGADGGSGGDGGDAGT
Mflv_5091|M.gilvum_PYR-GCK          AGATG-------------------------------------------AA
Mvan_1264|M.vanbaalenii_PYR-1       AGVTG-------------------------------------------AS
MSMEG_0868|M.smegmatis_MC2_155      NGGDGVVNTTANAANPGSATGTATGG----------------------DG
TH_3810|M.thermoresistible__bu      RGXX--------------------------------------------XX
MAB_4284c|M.abscessus_ATCC_199      SGSVG-------------------------------------------GS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SGG---------------------------------------------GH
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGTGG----------TGGAGGDGQNGTTGVASEGG--AGGQGGDGGQG-G
MUL_4367|M.ulcerans_Agy99           GGAGG----------VGGLGGDS-------AATAG--GGGAGGDGGKG-G
MMAR_2656|M.marinum_M               VGDGG----------VGGKGGDGAAGTTGSSGTASGEAGKDGGDGGKG-G
Mb3541|M.bovis_AF2122/97            GGNGGNGGNRNSGNGTGGAGGNGGGGANGGAGGAGGSGGGTGGNGGAG-G
Mflv_5091|M.gilvum_PYR-GCK          GASGG--------------------------------KGAQGATGAQG-A
Mvan_1264|M.vanbaalenii_PYR-1       GASGG--------------------------------KGAQGATGAQG-A
MSMEG_0868|M.smegmatis_MC2_155      GKATG--------------------------------TASQGGNGGPSWV
TH_3810|M.thermoresistible__bu      GGGVG--------------------------------AAVRSGNG----V
MAB_4284c|M.abscessus_ATCC_199      TAVGG---------------------------------GAHTGVGGGVNT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPTPG--------------------------------AGTPGGSGGGHLP
                                                                                      

Rv3508|M.tuberculosis_H37Rv         IGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDP-------SIDGG
MUL_4367|M.ulcerans_Agy99           AGGAGVNGVGG----GDGGKGGTGGAGGAGGAGSDGII-------PSNGG
MMAR_2656|M.marinum_M               AGGAGGNGGTSRGDGGAGGAGGTGGVGGSGGDGADGTSGLFGGADGTAGG
Mb3541|M.bovis_AF2122/97            DAGDAGNGGNGNG-TGNGGNGGNGGIAGMGGNGGAGTG-------SGNGG
Mflv_5091|M.gilvum_PYR-GCK          TGAQGATGATG----AAGKAGATGAAGAAGAAGSAGTT-------GAQGS
Mvan_1264|M.vanbaalenii_PYR-1       TGAQGATGATG----ASGAQGSAGSAGSAGVAGSAGTT-------GAQGS
MSMEG_0868|M.smegmatis_MC2_155      QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV-------MAAGT
TH_3810|M.thermoresistible__bu      FSGGG--------GTPSAGFGVPTT---IQFPAGSCTS-------RAVSR
MAB_4284c|M.abscessus_ATCC_199      GVGVGSHVGGG----ISESLGGSGSVGGSTAVGGGAHTS------AINDA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                FPGAGSTPGGS--------GGGHLPTPGAGTPGG------------GLGG
                                                                                      

Rv3508|M.tuberculosis_H37Rv         QGGAGGHGGQGGKGGLNSTGLA-------------SAASGDGGNGGAGGA
MUL_4367|M.ulcerans_Agy99           LGGNGGNGGNGGQ------------------------AFGDG--------
MMAR_2656|M.marinum_M               AGGDGGDGGAGGAGGAGGKAVSGVGQNGSQGAGGNGGAAGDGGDGGNGGN
Mb3541|M.bovis_AF2122/97            NGGSGGNGGNAGMGGNSGTGSG------------DGGAGGNGGAAGTGGT
Mflv_5091|M.gilvum_PYR-GCK          AGTNGANGANGSQ-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       AGTNGANGANGSQ-------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGVATGNTATGGDG------------------------------------
TH_3810|M.thermoresistible__bu      EGIMPSSRAASARA------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LGGSGSVGGSTAVG------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                FGGGHAPAPGGGLG------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGNGGDGDGFIGGSGGTGGTG---GDAGVGGLANTGGTAGNAGIGGAGGR
MUL_4367|M.ulcerans_Agy99           ----------VGGAGGIGGKG---GNAAIGTIVING--------------
MMAR_2656|M.marinum_M               GHDGNNGSVPSGGTDRDGGDGQGGGDGGAGGAGGAGGNGGAAGAGGGGTR
Mb3541|M.bovis_AF2122/97            GGDGGLTG--TGGTGGSGGTG---GDGGNGGNGGNGADNTANMTAQAG--
Mflv_5091|M.gilvum_PYR-GCK          -----------GAAGKAGATG---TTGATGAAGEDG--------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GAAGKAGATG---TTGATGAAGDAG--------------
MSMEG_0868|M.smegmatis_MC2_155      -----------GAATTAGATG---GAGGFSNIAAIHG-------------
TH_3810|M.thermoresistible__bu      -----------GAACASSTSR---SRRSFCCSRA----------------
MAB_4284c|M.abscessus_ATCC_199      -----------GGAHTSAINESMNSSINASHSSSMNES------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------GGGGHAPAPG-----------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGA
MUL_4367|M.ulcerans_Agy99           ------------------------------------GVGGAGGSGGLGGA
MMAR_2656|M.marinum_M               GAGGDGGDGGNGGFAGDGGLGMDGLDATLTNRAGDGGDGGGGGQAFAGGA
Mb3541|M.bovis_AF2122/97            ---GDGGNGGDGGFGGGAGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGH
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------DAGSGGSGINGGA
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------DPGSEAVDINGGA
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------AITDSTAISGHG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------FGSSMGSHGAAGT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         G-------GDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVP
MUL_4367|M.ulcerans_Agy99           T-------EDG---------------------------------------
MMAR_2656|M.marinum_M               G-------GAGGTGSTQGSAGTTGAWRAGGDGGSGGDGGDGFGLWNPGEG
Mb3541|M.bovis_AF2122/97            GPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTG
Mflv_5091|M.gilvum_PYR-GCK          G-------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       G-------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      G-------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G-------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GDGG-IGGTGGAGGAGGAGADGDPSIDGGQGGAGGH-----GGQGGKGGL
MUL_4367|M.ulcerans_Agy99           -----VGGVGCAGGAG--------------------------GNGGRGDM
MMAR_2656|M.marinum_M               GRGG-SGGDGGTGGDGGDGGNGRVEIWEGRGGNGGNGAIGPGGDGGDGGD
Mb3541|M.bovis_AF2122/97            GEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGAGG----TGGTGGTGGL
Mflv_5091|M.gilvum_PYR-GCK          -------GAGGAGGEGG---------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------GAGGAGGEGG---------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------AGNGGNGGKGADGWVQAYDPAGPVGSKIAN--------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         NSTGLASAASGDGGNGGAGGAGGNGGAGGLGGGGGTGGT------NGNGG
MUL_4367|M.ulcerans_Agy99           LFT-----------VGGSGGTGGDGGGGGSASGSGTGGS------GGTGG
MMAR_2656|M.marinum_M               APNQQRVSSSSPGYEGADGGNGGNGTIGGNGGNGGTGGPGYDASLGGEAT
Mb3541|M.bovis_AF2122/97            GDPR----VGGSGGDGGTGGSGGAAGNGGNGGNAGAGGNGN----GGTGG
Mflv_5091|M.gilvum_PYR-GCK          --------------EGGDGGKGGAGAEGGAGGGGGAGGS-------GAGG
Mvan_1264|M.vanbaalenii_PYR-1       --------------EGGAGGAGGDGSEGGAGGSGGAGGS-------GTGG
MSMEG_0868|M.smegmatis_MC2_155      --------------SSAVAGNGGDGGVNGTGGASGGDGGN-----GGNTS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------FEAQGHAQGHASETAHTTLPGAEHH-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------GGLGGFGGGHSGGGLGGLGGGHK------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         LGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATGVGNGGNG
MUL_4367|M.ulcerans_Agy99           VGGIGGDGKLG------------------------------------GFG
MMAR_2656|M.marinum_M               AGGEGGDGGDGGKGFNGAG----GAGGDGGAGGAGGSGAPAPFGSGGAYG
Mb3541|M.bovis_AF2122/97            AGGIGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNGSGTGSGGTG
Mflv_5091|M.gilvum_PYR-GCK          AGGAGGS------------------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGGS------------------------------------------G
MSMEG_0868|M.smegmatis_MC2_155      VWKSGGQTADG----------------------------------EHNTG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GDGGNGGDGGNGAPGGFGGGA--GAGGLGG-------SGAGGGTDGDDGN
MUL_4367|M.ulcerans_Agy99           GDGGDGGDGGFGVIGGQGGGG--GFGGLGG-------TGAGG-APSDKGI
MMAR_2656|M.marinum_M               GTGGQGGTGGSGVIGGIGEGGKIGDAGFGGN-PPNSQTGEGG-SGGAGGA
Mb3541|M.bovis_AF2122/97            GDGGTGGGGGNGGTGWNGGKGDTGSGGGAGD-GGKAPAGGTGGAGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          GSGGSGGSGGSGGAAGDSDD------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GSGGSGGAGGSGGAAGDSD-------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3508|M.tuberculosis_H37Rv         GGSPGTDGS------
MUL_4367|M.ulcerans_Agy99           NGEPGNPG-------
MMAR_2656|M.marinum_M               GGAGGDPSN------
Mb3541|M.bovis_AF2122/97            GGKGGSGGV------
Mflv_5091|M.gilvum_PYR-GCK          ---------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------
MSMEG_0868|M.smegmatis_MC2_155      DGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      ---------------
MAB_4284c|M.abscessus_ATCC_199      ---------------
MLBr_01183|M.leprae_Br4923          ---------------
MAV_4827|M.avium_104                ---------------