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M. marinum M MMAR_3657 (plcB_4)

annotation: membrane-associated phospholipase C 2 PlcB_4
coordinates: 4503965 - 4505527
length: 520 

SGNPFRGMSRREFIAKMTGAGAAALLMDYAGPVIEKAYGAGPCSGQLTDIEHIVLLMQENRSFDHYFGTL
SSIRGFSDPSPAFQQKGWNPRTQALDPAGTTIPFRLDTTRGPFLDGECVNDPEHQWTAMHLSWNGGANDN
WLPAQANTRTGPYVPMTMGYYTRQDIPIHHLLADTFTICDGYHCSLLTGTLPNRLYWMSAWNDPAGTNGG
PQLVEPGFLPLHQYSWRIMPENLEDAGVSWKVYQNKDAGRFINTPISNNGLVQAFKQSGDPRSNLARYGI
APGYPVDFAADVKANRLPKVSWLVPNFLQSEHPALPVALGAVAMVTALRILLSNPAVWEKTALIISYDEN
GGFFDHVTPPTAPPGTPGEWVTVPDINSVPGSGGIRGPLGLGFRVPCIVVSPFSRGGLMVHDIFDHTSQL
KLISKRFDVPVPNLTAWRDGVVGDMTSTFNFATPPNPSRPNLSHPLLAAVPKLPQCIPNVVLGTSDGTFP
AIPYRVPYPQSMPGQESTPVRGVPSGLCV*

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3657plcB_4-100% (520)membrane-associated phospholipase C 2 PlcB_4
M. marinum MMMAR_0284plcB_30.072.94% (521) membrane-associated phospholipase C 2 PlcB_3
M. marinum MMMAR_3823plcB_10.070.58% (520) membrane-associated phospholipase C 2 PlcB_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1784cplcD0.069.36% (519) phospholipase C 4 PLCD
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2351cplcA0.087.08% (511) membrane-associated phospholipase C
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0555-7e-9238.93% (506) non-hemolytic phospholipase C
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2799plcB0.069.26% (514) membrane-associated phospholipase C 2 PlcB
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3657|M.marinum_M               MSGNPFRGMSRREFIAKMTGAGAAALLMDYAGPVIEKAYG-AGPCSGQLT
Rv2351c|M.tuberculosis_H37Rv        --------MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYG-AGPCPGHLT
MUL_2799|M.ulcerans_Agy99           --------MSRREFMAKLAAASSAGAMMSLAGPVIEKAYG-AGPCSGHLT
Mb1784c|M.bovis_AF2122/97           MSQSHIGGVSRREFLAKVAAGG-AGALMSFAGPVIEKAYG-AGPCSGHLT
MAB_0555|M.abscessus_ATCC_1997      -----MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLR
                                            ::**.:::. :. .  .  :.   . :::. . ..* .* * 

MMAR_3657|M.marinum_M               DIEHIVLLMQENRSFDHYFGTLSSIRGFSDPSPAFQQKGWNPRTQA--LD
Rv2351c|M.tuberculosis_H37Rv        DIEHIVLLMQENRSFDHYFGTLSSTNGFNAASPAFQQMGWNPMTQA--LD
MUL_2799|M.ulcerans_Agy99           DIEHFVFMLQENRSFDHYFGSLSGINGFDTPSSAFQQKGWNPQTQS--ID
Mb1784c|M.bovis_AF2122/97           DIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSPLFQQKGWNPMTQA--LD
MAB_0555|M.abscessus_ATCC_1997      DVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVTLSTGKSVFHQPDPQN
                                    *:**.*.:: **********:**.  **.  :.   . * .   *.   :

MMAR_3657|M.marinum_M               PAGTTIPFRLDTTRGPFLDGECVNDPEHQWTAMHLSWNGGANDNWLPAQA
Rv2351c|M.tuberculosis_H37Rv        PAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPAQA
MUL_2799|M.ulcerans_Agy99           PAGVTIPYRFDTTRGPLLNGACANDPGHQWIDMHRAFNNGANDNWLGAQA
Mb1784c|M.bovis_AF2122/97           ATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQA
MAB_0555|M.abscessus_ATCC_1997      PDGYLLPFHLDTAVNSVQK---IPTTSHAWSVQHDSWNHGKMDNWMAAHR
                                    . *  :*:::**: ... .      . * *   * ::* *  ***: *: 

MMAR_3657|M.marinum_M               NTRTGP-YVPMTMGYYTRQDIPIHHLLADTFTICDGYHCSLLTGTLPNRL
Rv2351c|M.tuberculosis_H37Rv        TTRAGP-YVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRL
MUL_2799|M.ulcerans_Agy99           QAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHCSLIGGTSPNRL
Mb1784c|M.bovis_AF2122/97           KTRSAA-HTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRL
MAB_0555|M.abscessus_ATCC_1997      KADGEH--YPYVMGYYERADIPFHFALAEAFTVCDNFHSSVMGPTWPNRM
                                     :       * .**** * * *:*. **::**:** :..*::  * ***:

MMAR_3657|M.marinum_M               YWMSAWNDPAGTNGGPQLVEPGFLPLHQYSWRIMPENLEDAGVSWKVYQN
Rv2351c|M.tuberculosis_H37Rv        YWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQN
MUL_2799|M.ulcerans_Agy99           YWMSAWVDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQN
Mb1784c|M.bovis_AF2122/97           YWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRN
MAB_0555|M.abscessus_ATCC_1997      MWMTGTIDPDAAHGGPIIRNTPVS--GGYGWTTYAERLEAAGVSWRVYAE
                                     *::.  ** . .*** : .. .     :.*   .:.*. **:**:** :

MMAR_3657|M.marinum_M               KDAGRFINTPISNNGLVQAFKQSGDPRSNLARYGIAPGYPVDFAADVKAN
Rv2351c|M.tuberculosis_H37Rv        KGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRAN
MUL_2799|M.ulcerans_Agy99           KLLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVASN
Mb1784c|M.bovis_AF2122/97           KTLG-PISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLAN
MAB_0555|M.abscessus_ATCC_1997      EDDYGGCNVLK----LFSRFQRSR-PGEPLYDKGIAPVRATQFEDDARAG
                                    :      .       :.  * ::  * . :   *:**  . .*  *. :.

MMAR_3657|M.marinum_M               RLPKVSWLVPNFLQSEHPALPVA--LGAVAMVTALRILLSNPAVWEKTAL
Rv2351c|M.tuberculosis_H37Rv        RLPKVSWLVPNILQSEHPALPVA--LGAVSMVTALRILLSNPAVWEKTAL
MUL_2799|M.ulcerans_Agy99           RLPQVSWVLPGFQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTAL
Mb1784c|M.bovis_AF2122/97           RLPRVSWVIPNVLESEHPAVPAA--AGAFAIVNILRILLANPAVWEKTAL
MAB_0555|M.abscessus_ATCC_1997      RLPAVSWLIMTSTASEHPDYRPA--DGAAYIASKIDAIAANPEVWAKTVF
                                    *** ***::     ****    *   *.  :.. :  : :** ** **.:

MMAR_3657|M.marinum_M               IISYDENGGFFDHVTPPTAPPGTPGEWVTVPDINSVPGSGGIRGPLGLGF
Rv2351c|M.tuberculosis_H37Rv        IVSYDENGGFFDHVTPPTAPPGTPGEFVTVPNIDAVPGSGGIRGPLGLGF
MUL_2799|M.ulcerans_Agy99           IVSFDENGGFFDHVTPTTAPEGTPGEWITVPDINAVTGSGGIRGPIGLGY
Mb1784c|M.bovis_AF2122/97           IVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGF
MAB_0555|M.abscessus_ATCC_1997      ILNYDENDGLFDHVVPPTPPPGTPGEWVKG-------------VPIGGGF
                                    *:.:***.*:****.*.*.* *****::.               *:* *:

MMAR_3657|M.marinum_M               RVPCIVVSPFSRGGLMVHDIFDHTSQLKLISKRFDVPVPNLTAWRDGVVG
Rv2351c|M.tuberculosis_H37Rv        RVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVG
MUL_2799|M.ulcerans_Agy99           RVPCFVISPYSRGPLMVHDIFDHTSQLRLLEQRFGVPVPNLTTWRRGVTG
Mb1784c|M.bovis_AF2122/97           RVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTG
MAB_0555|M.abscessus_ATCC_1997      RVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRRKTFG
                                    ***.:*:**:* *  :. : ***** *:::    .*  **:: **  . *

MMAR_3657|M.marinum_M               DMTSTFNFATPPNPSRPNLSHPLLAAVPKLPQCIPNVVLGTSDGTFPAIP
Rv2351c|M.tuberculosis_H37Rv        DMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIP
MUL_2799|M.ulcerans_Agy99           DMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVTVFTK-TVP--P
Mb1784c|M.bovis_AF2122/97           DMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINRGIP---
MAB_0555|M.abscessus_ATCC_1997      NLLSAFGFDSPVRPAPELPDTAAVVAAADRTDTRP-------PPVIP---
                                    :: *:*.*  * ..:    . . : * .   :  *          .*   

MMAR_3657|M.marinum_M               YRVPYPQSMPGQES-TPVRGVPSGLCV
Rv2351c|M.tuberculosis_H37Rv        YRVPYPQVMPTQET-TPVRGTPSGLCS
MUL_2799|M.ulcerans_Agy99           YRVPFPQVMPSQET-SPTRGIPSGPC-
Mb1784c|M.bovis_AF2122/97           YRVPDPQIMPTQET-TPTRGIPSGPC-
MAB_0555|M.abscessus_ATCC_1997      ---PAPQTSPVQEPGSRPRRYPRR---
                                       * **  * **. :  *  *