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MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSFDHYFGTLSGV RGFDDPTAVTLSTGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSHAWSVQHDSWNHGKMDNWMAA HRKADGEHYPYVMGYYERADIPFHFALAEAFTVCDNFHSSVMGPTWPNRMMWMTGTIDPDAAHGGPIIRN TPVSGGYGWTTYAERLEAAGVSWRVYAEEDDYGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDA RAGRLPAVSWLIMTSTASEHPDYRPADGAAYIASKIDAIAANPEVWAKTVFILNYDENDGLFDHVVPPTP PPGTPGEWVKGVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRRKTFGNL LSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0555 | - | - | 100% (479) | non-hemolytic phospholipase C |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1784c | plcD | 6e-91 | 41.08% (499) | phospholipase C 4 PLCD |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2350c | plcB | 1e-93 | 39.68% (504) | membrane-associated phospholipase C |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4722 | plcB_6 | 1e-100 | 41.15% (503) | membrane-associated phospholipase C 2 PlcB_6 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2799 | plcB | 1e-87 | 36.78% (503) | membrane-associated phospholipase C 2 PlcB |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2350c|M.tuberculosis_H37Rv ---------MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYG-AGPCPGHL
MUL_2799|M.ulcerans_Agy99 ---------MSRREFMAKLAAASSAGAMMSLAGPVIEKAYG-AGPCSGHL
Mb1784c|M.bovis_AF2122/97 -MSQSHIGGVSRREFLAKVAAGG-AGALMSFAGPVIEKAYG-AGPCSGHL
MMAR_4722|M.marinum_M MTWADAVDKMSRREFLAKLAAATSTGALMSLAGPVIEKAYG-AGPCSGHL
MAB_0555|M.abscessus_ATCC_1997 ------MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSL
::**.:::. *. .* :*: . :::. . ..* .* *
Rv2350c|M.tuberculosis_H37Rv TDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFAQSGWNPMTQAV
MUL_2799|M.ulcerans_Agy99 TDIEHFVFMLQENRSFDHYFGSLSGINGFD--TPSSAFQQKGWNPQTQSI
Mb1784c|M.bovis_AF2122/97 TDIEHFVFFMQENRSFDHYFGTLSGTDGFN--TVSPLFQQKGWNPMTQAL
MMAR_4722|M.marinum_M TDIEHIVLLMQENRSFDHYFGTLSDVEGFD--TPTPLFAQKGWNPRTQAP
MAB_0555|M.abscessus_ATCC_1997 RDVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVTLSTGKSVFHQPDPQ
*:**.*.:: **********:**. **: * .. .:.
Rv2350c|M.tuberculosis_H37Rv DPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQ
MUL_2799|M.ulcerans_Agy99 DPAGVTIPYRFDTTRGPLLNGACANDPGHQWIDMHRAFNNGANDNWLGAQ
Mb1784c|M.bovis_AF2122/97 DATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQ
MMAR_4722|M.marinum_M DPASTTLPFRLDTTRPPLLNGACVNDPDHGWATLHDSWNGGANDNWLPAQ
MAB_0555|M.abscessus_ATCC_1997 NPDGYLLPFHLDTAVNSVQK---IPTTSHAWSVQHDSWNHGKMDNWMAAH
:. . :*:::**: .. ..* * * ::* * ***: *:
Rv2350c|M.tuberculosis_H37Rv VPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNR
MUL_2799|M.ulcerans_Agy99 AQAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHCSLIGGTSPNR
Mb1784c|M.bovis_AF2122/97 AKTRSAA-HTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNR
MMAR_4722|M.marinum_M ARTRSAA-NIPATLGYHTRDDLPIHFLLADTFTVCDHYFCSVIGPTFPNR
MAB_0555|M.abscessus_ATCC_1997 RKADGEH--YPYVMGYYERADIPFHFALAEAFTVCDNFHSSVMGPTWPNR
* .:*:: * * *:*: **::**:** :..*::* * ***
Rv2350c|M.tuberculosis_H37Rv LYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ
MUL_2799|M.ulcerans_Agy99 LYWMSAWVDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQ
Mb1784c|M.bovis_AF2122/97 LYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYR
MMAR_4722|M.marinum_M LYWVSAWLDPDGANGGPLVETIPTPPIGKFSWPIMPQHLSDAGVSWKIYY
MAB_0555|M.abscessus_ATCC_1997 MMWMTGTIDPDAAHGGPIIRNTPVS--GGYGWTTYAERLEAAGVSWRVYA
: *::. :**:. .*** : :.* .:.*. **:**::*
Rv2350c|M.tuberculosis_H37Rv NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRN
MUL_2799|M.ulcerans_Agy99 NKLLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVAS
Mb1784c|M.bovis_AF2122/97 NKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLA
MMAR_4722|M.marinum_M DKRLGPAVNSYVGYGEIVRWFTQAQDPRSDLVRFGATPRYPRDFATDVKA
MAB_0555|M.abscessus_ATCC_1997 EE----DDYGGCNVLKLFSRFQRSR-PGEPLYDKGIAPVRATQFEDDARA
:: :. * :: * . : * :* . .* *.
Rv2350c|M.tuberculosis_H37Rv NRLPKVSWVLPGFLLSEHPAFPVN--VGAVAIVDALRILLSNPAVWEKTA
MUL_2799|M.ulcerans_Agy99 NRLPQVSWVLPGFQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTA
Mb1784c|M.bovis_AF2122/97 NRLPRVSWVIPNVLESEHPAVPAA--AGAFAIVNILRILLANPAVWEKTA
MMAR_4722|M.marinum_M NRLPQVSWLIPNFLESEHPAMPNAG--GAIAFMDVLRILLSNPAVWEKTA
MAB_0555|M.abscessus_ATCC_1997 GRLPAVSWLIMTSTASEHPDYRPAD--GAAYIASKIDAIAANPEVWAKTV
.*** ***:: **** *. : . : : :** ** **.
Rv2350c|M.tuberculosis_H37Rv LIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLG
MUL_2799|M.ulcerans_Agy99 LIVSFDENGGFFDHVTPTTAPEGTPGEWITVPDINAVTGSGGIRGPIGLG
Mb1784c|M.bovis_AF2122/97 LIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLG
MMAR_4722|M.marinum_M LIVSYDENGGFFDHVVPPTPPDGTPGEYLTVPDIDKVRGSGGIRGPIGLG
MAB_0555|M.abscessus_ATCC_1997 FILNYDENDGLFDHVVPPTPPPGTPGEWVKG-------------VPIGGG
:*:.:***.*:****.*.*.* *****::. *** *
Rv2350c|M.tuberculosis_H37Rv FRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATV
MUL_2799|M.ulcerans_Agy99 YRVPCFVISPYSRGPLMVHDIFDHTSQLRLLEQRFGVPVPNLTTWRRGVT
Mb1784c|M.bovis_AF2122/97 FRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVT
MMAR_4722|M.marinum_M YRVPGLVISPFSRGGLVAHDVFDHTSQLRLIETRFGVPVPNLTAWRRSVT
MAB_0555|M.abscessus_ATCC_1997 FRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRRKTF
:*** :****:* * :. : ***** *:::. ** **:: ** .
Rv2350c|M.tuberculosis_H37Rv GDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQC-VPNAVLGTVTKTAIP
MUL_2799|M.ulcerans_Agy99 GDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQC-VPDTVT-VFTKTVPP
Mb1784c|M.bovis_AF2122/97 GDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQC-VPNAALGTINR-GIP
MMAR_4722|M.marinum_M GDMTSAFNFGVPPNPSRPNLNQ-SKRVLPQLAQCGLGVEAVAGIFELNPP
MAB_0555|M.abscessus_ATCC_1997 GNLLSAFGFDSP------------VRPAPELPDTAAVVAAADRTDTRPPP
*:: *:*.* * . . : . *
Rv2350c|M.tuberculosis_H37Rv YRVPFPQSMPTQE-TAPTRGIPSGLC
MUL_2799|M.ulcerans_Agy99 YRVPFPQVMPSQE-TSPTRGIPSGPC
Mb1784c|M.bovis_AF2122/97 YRVPDPQIMPTQE-TTPTRGIPSGPC
MMAR_4722|M.marinum_M YRVPYPQAMPAQE-TTPARGIPSGLC
MAB_0555|M.abscessus_ATCC_1997 VIPPAPQTSPVQEPGSRPRRYPRR--
* ** * ** : .* *