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MSLVIAVPELVEAAATELAGIGSALGQATAGAASPTVNILAAAEDEVSAAIAAVFSGHAQAYQAASAQAQ VFQRQFAQALAAGATSYAGAESAAAAALANPAQVVPQDLLGAINAPVLALTGRPLIGNGANGAPGTGAAG APGGWLLGDGGAGGSGAPGKAGGAGGAAGLWGSGGAGGAGGSTSSGVAGAGGAGGAGGWLLGTGGAGGAG GYTTSGTGGAGGAGGTGGLLGGGGVGGAGGMAYSAGTTGGAGGAGGAGGVLSGLVGAGGGHGGTGGAGSG TGGAGGAGGPAGLLGGPGGAGGDGGYGDTGGAGGAGGAGGWLFGNGGAGGTGGTSIGSTGGAGGTGGNAG WLGNGGTGGTGGFSRYGLGGDGGTGGNAGWLGNGGTGGTGGFSGSGLGGDGGYGGTAGLLIGNGGAGGTG AQGATGGGAGGTGGNAVLIGNGGNGAMGGTGPTVGATGAGGMSGLLLGLDGYNAPTSTSPIHVAQQQALA AINTPAQALTGRPLIGNGTPGATGSGADGTPGGWLLGDGGAGGSGLAGRDGGAGGAAGLWGTGGTGGAGG RGGTGGDGGAGGAGGWFSGDGGVGGIGGGSTAAGATGGTGGTGGAGGLFGAGGNGGAGGAGTYFISAFGG AGGTGGSGGLLSGLVGAGGGHGGAGGTAISNSGAGGAGGAGGDAGLLGGPGGAGGTGGPGDFGTTHGGAG GAGGNAGLLFGSGGTGGTGGYGASAGDGGHGGSAGLLFSGAGAGGAGGVGLSGPGGAGGRGGDAGWLGDG GAGGTGGSSHYGDGGDGGAGGAAGQLSGGGGAGGQGGQGNIAGAVTRTGGDGGAGGDAVLIGNGGNGGNG GTDGTGAPTGSPGAGGTGGILLGADGNDGLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3326 | - | - | 100% (871) | PE-PGRS family protein |
| M. marinum M | MMAR_1195 | - | 0.0 | 74.80% (889) | PE-PGRS family protein, PE_PGRS9_4 |
| M. marinum M | MMAR_4399 | - | 0.0 | 65.26% (924) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 62.61% (880) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-151 | 45.86% (785) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 64.47% (819) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 3e-11 | 32.42% (256) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-46 | 33.05% (475) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 3e-24 | 42.62% (183) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-130 | 40.49% (899) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-41 | 41.72% (290) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 60.47% (888) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-151 | 47.82% (734) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3326|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGSVLGAADAAA
Rv0746|M.tuberculosis_H37Rv ------------------MSFVLAMPEVLGSAATDLAALGSVLGAADAAA
MMAR_3326|M.marinum_M ------------------MSLVIAVPELVEAAATELAGIGSALGQATAGA
MUL_3062|M.ulcerans_Agy99 ------------------MAFVLAVPDMVAEAAADLAGVGSVIDAANTAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSA
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED
MLBr_01556|M.leprae_Br4923 ---------------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSA
Mb0767|M.bovis_AF2122/97 AATTTG------------------IVAAVQDEVSAAIAALFSAHGRAYQV
Rv0746|M.tuberculosis_H37Rv AATTTG------------------IVAAAQDEVSAAIAALFSAHGRAYQV
MMAR_3326|M.marinum_M ASPTVN------------------ILAAAEDEVSAAIAAVFSGHAQAYQA
MUL_3062|M.ulcerans_Agy99 AGSTTG------------------IVAAAEDEVSAAIAALFSGHGQAYQQ
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSAAQVG---------------------AVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104 AIDVTG------------------ADDAATASAPDRVISAILGTREGAAD
MLBr_01556|M.leprae_Br4923 SSTVEAP-----------------VARRLRESFGGIKPAADKGAEQVATK
Mb0767|M.bovis_AF2122/97 AS---------------------------AQAAAVHAQFVEALSAGAGAY
Rv0746|M.tuberculosis_H37Rv AS---------------------------AQAAAVHAQFVEALSAGAGAY
MMAR_3326|M.marinum_M AS---------------------------AQAQVFQRQFAQALAAGATSY
MUL_3062|M.ulcerans_Agy99 IS---------------------------TRVAEFHAQFERVFAAGVQAY
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TG-----------------------------------NPIHDLSGNLQNY
MAV_4827|M.avium_104 AG--------------------------------------LQLSSIGVTW
MLBr_01556|M.leprae_Br4923 AQAKR-------------------------LGESLDQTLDRALDKAVAGN
Mb0767|M.bovis_AF2122/97 AS-----------------------AEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv AS-----------------------AEAAGAAVLANPAQSVQQDLLAAVN
MMAR_3326|M.marinum_M AG-----------------------AESAAAAALANPAQVVPQDLLGAIN
MUL_3062|M.ulcerans_Agy99 SG-----------------------AEAANASFLQDPLQTA----LNATN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YA-----------------------AQPDGPSILSPSLLSPRDNDFLSHN
MAV_4827|M.avium_104 TD-------------------------QLEAAALRDALAARRIDNVMLVS
MLBr_01556|M.leprae_Br4923 GATT---------------------AAPVQVDHSAAVVPIVAGEGPSTAH
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
MMAR_3326|M.marinum_M APVLALTGRPLIGNGANGAPG-----TGAAGAPGGWLLGDGGAGGSGAP-
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAA-
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG-
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG-
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA-
TH_3810|M.thermoresistible__bu ----------------------------VDG-------------------
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG
MAV_4827|M.avium_104 AFLAAAALAQNVG-GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQ
MLBr_01556|M.leprae_Br4923 REELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGG
Mb0767|M.bovis_AF2122/97 SGLPGGAGGAAG---LFGTGGAGGAGGSS---TVGDGG--AGGAGGSGGW
Rv0746|M.tuberculosis_H37Rv SGLPGGAGGAAG---LFGTGGAGGAGGSS---TVGDGE--AGGAGGSGGW
MMAR_3326|M.marinum_M -GKAGGAGGAAG---LWGSGGAGGAGGST---SSGVAG--AGGAGGAGGW
MUL_3062|M.ulcerans_Agy99 -GQAGGDGGAAG---LIGAGGAGGAGGNSPLRNTANGG--NGGTGGAGGL
Mflv_5091|M.gilvum_PYR-GCK -GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 -SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 -GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu ---DGGSGGRTG---LFSKLSRGGDGGDG---------------------
MAB_4284c|M.abscessus_ATCC_199 DGAVAVGGSNSG-------PIASGQGSTAVNGDVRDSNIINADHGSNVGV
MAV_4827|M.avium_104 QIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTT
MLBr_01556|M.leprae_Br4923 RPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRP
. .
Mb0767|M.bovis_AF2122/97 LLGTGGVGGVG-----GLG-AGAGGAGGVGGAGGLLG-------------
Rv0746|M.tuberculosis_H37Rv LLGTGGVGGVG-----GLG-AGAGGAGGVGGAGGLLG-------------
MMAR_3326|M.marinum_M LLGTGGAGGAG-----GYTTSGTGGAGGAGGTGGLLG-------------
MUL_3062|M.ulcerans_Agy99 LFGPGGVGGAG-----GAS-FLTGGTGGDGGAGGLFG-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu ---------------------GLGGNGGHGGGTG----------------
MAB_4284c|M.abscessus_ATCC_199 DQSQTRVGG-------DYTNVSGHGSADIDKSVTVVD-------------
MAV_4827|M.avium_104 TFLDVSVAEEP-------ETALARGAALAAANAPLFAS------------
MLBr_01556|M.leprae_Br4923 PRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALP-------------
*
Mb0767|M.bovis_AF2122/97 -------AGGHGGAGGLG-----AVTGGVGGAGGAGG-------------
Rv0746|M.tuberculosis_H37Rv -------AGGHGGAGGLG-----AVTGGVGGTGGAGG-------------
MMAR_3326|M.marinum_M -------GGGVGGAGGMAY--SAGTTGGAGGAGGAGG-------------
MUL_3062|M.ulcerans_Agy99 -------AGGLGGVGGSG------NVGGNGGAGGAGG-------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------DHSQRNTTNINDSFNTDRSTNIGSGNTTNT-------------
MAV_4827|M.avium_104 ----------------------STAALAYAQDPGTG--------------
MLBr_01556|M.leprae_Br4923 ----------GGGSGGFRGRPGGGGHGGGGRPGQRGG-------------
Mb0767|M.bovis_AF2122/97 --LLAGLLAGP--------GGAGGTGGR----------------------
Rv0746|M.tuberculosis_H37Rv --LLAGLLAGP--------GGAGGTGGR----------------------
MMAR_3326|M.marinum_M --VLSGLVGAG--------GGHGGTGGAGSGTGGAGGAGGPAGLLGGPGG
MUL_3062|M.ulcerans_Agy99 --LLAGLVGAG--------GGDGGSGGLGAAGGDGGNGGRAGLFGGAGGA
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --IISLLSLAG---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --EIGSHNQAN---------------------------------------
MAV_4827|M.avium_104 --AVDQYSLPD---------------------------------------
MLBr_01556|M.leprae_Br4923 --AAGAFGRPG---------------------------------------
Mb0767|M.bovis_AF2122/97 -----GFLNDGGVG----------------GAGGNAGLLFGAGGTGGSGG
Rv0746|M.tuberculosis_H37Rv -----GFLNNGGVG----------------GAGGNAGLLFGAGGTGGSGG
MMAR_3326|M.marinum_M AGGDGGYGDTGGAG----------------GAGGAGGWLFGNGGAGGTGG
MUL_3062|M.ulcerans_Agy99 GGMGATGGHSGGDG----------------GAGGDAGLLFGTGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu ---------NGGNG------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------IGTSTSAG-----------------GSAAVGGNAGLAGNAGLAG
MAV_4827|M.avium_104 ---YLYVPVDPEPG--------------------DDELAYSAVGEEDAES
MLBr_01556|M.leprae_Br4923 -----GAPRRGRKS------------------KRQKRQEYDSMQAPVVGG
.
Mb0767|M.bovis_AF2122/97 AGLGGDGGAGGAG--GNAGVLFGNAGSGGTG-------GFG---------
Rv0746|M.tuberculosis_H37Rv AGLGGDGGAGGAG--GNTGVLFGNAGSGGTG-------GFG---------
MMAR_3326|M.marinum_M TSIGSTGGAGGTG--GNAG-WLGNGGTGGTG-------GFSR--------
MUL_3062|M.ulcerans_Agy99 HAFDGDGGAGGAG--GNAGLMFSSGGSGGVG-------GAG---------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ---------------GNGYRTTDNN-------------------------
MAB_4284c|M.abscessus_ATCC_199 N----AGLAGNAGLAGNAGLAGNAGLAGNAG-------------------
MAV_4827|M.avium_104 P----TVVIEKLFLPEDSEPRRRPVLLVGSG-------------------
MLBr_01556|M.leprae_Br4923 VRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLG---------
Mb0767|M.bovis_AF2122/97 ---------DTDGGAGGAGGDAGWLGS----------------------G
Rv0746|M.tuberculosis_H37Rv ---------DTDGGAGGAGGDAGWLGS----------------------G
MMAR_3326|M.marinum_M ---------YGLGGDGGTGGNAGWLGN----------------------G
MUL_3062|M.ulcerans_Agy99 ---------SIDGGAGGAGGDAGWLGG----------------------G
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu ---------ALDGGHGGNGGNVGFFSL----------------------F
MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAGLAGN----------------------A
MAV_4827|M.avium_104 --------LAVVGISAVLALEIALAIG----------------------I
MLBr_01556|M.leprae_Br4923 ---------EMVTATQSVGDETLELLG----------------------S
. :
Mb0767|M.bovis_AF2122/97 GVGGAGGFGETG-------------------DGGVGGAGGKA--------
Rv0746|M.tuberculosis_H37Rv GVGGAGGFGETG-------------------DGGVGGAGGKA--------
MMAR_3326|M.marinum_M GTGGTGGFSGSG-------------------LGGDGGYGGTA--------
MUL_3062|M.ulcerans_Agy99 GAGGAGGFGTIS-------------------DGGAGGRGGGG--------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu NLGGAGGWGGSG-------------------VDGVDVVGGNP--------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG------------------LAGNAGLAGNAG-------
MAV_4827|M.avium_104 RTTGTVALQPTPN---------------QHLIVPTEQAPAPP--------
MLBr_01556|M.leprae_Br4923 EMNYNVQVVSPEDEDR-------------ELLEPFDLTYGED--------
.
Mb0767|M.bovis_AF2122/97 ----------GLLIGNGGAGGAG---------------------------
Rv0746|M.tuberculosis_H37Rv ----------GLLIGNGGAGGAGGQGAVTGGTGGAGGDG-----------
MMAR_3326|M.marinum_M ----------GLLIGNGGAGGTGAQGATGGGAGGTGGNA-----------
MUL_3062|M.ulcerans_Agy99 ----------GQLLGNGGAGGAGGQGGNDGGAGGLGGNG-----------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu ---------------DGGT-------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAG--------------------------
MAV_4827|M.avium_104 -------------PVQASAPQPK---------------------------
MLBr_01556|M.leprae_Br4923 -------------QGDEDELQVRPPVVTVMGHVDHGKTR----------L
.
Mb0767|M.bovis_AF2122/97 VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQ
Rv0746|M.tuberculosis_H37Rv VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNTPASASPLHTLKQ
MMAR_3326|M.marinum_M VLIGNGGNGAMGGTGPTVGATGAGGMSGLLLGLDGYNAPTSTSPIHVAQQ
MUL_3062|M.ulcerans_Agy99 VLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADGFNAPAGSSPVHALQQ
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTG-GTGGTG-GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTG-GTGGTG-GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAG-GAGGVSEGEGGTGGHGGDG
TH_3810|M.thermoresistible__bu ----PGAHGESHTPGVYTDRQGEDGEDGTGTGIGGRGGNGGSSSGTHPMA
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGNAGLA-GNAGLAGNAAVAGNAAVAG
MAV_4827|M.avium_104 ----ISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVP
MLBr_01556|M.leprae_Br4923 LDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTA
. . .
Mb0767|M.bovis_AF2122/97 QALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAPGG-----WLLGDGGA
Rv0746|M.tuberculosis_H37Rv QALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAPGG-----WLLGDGGA
MMAR_3326|M.marinum_M QALAAINTPAQALTGRPLIGNGTPGATGSGADGTPGG-----WLLGDGGA
MUL_3062|M.ulcerans_Agy99 QALAAINAPVQELTGRPLIGNGLPGSAGSGAAGAPGG-----WLLGDGGA
Mflv_5091|M.gilvum_PYR-GCK GKGGTGGTGGAGGTG----GDGGTG--GTGGTGGTG---------GTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GKGGTGGTGGDGGTG----GTGGTG--GTGGTGGTG---------GTGGT
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVGLGNGGKG--GNGGNGGNGGTYVDPSHTGAGGN
TH_3810|M.thermoresistible__bu EDGEHVKALD-------------------GRPGLDG---------GNGSH
MAB_4284c|M.abscessus_ATCC_199 NAAVAGNAAVGGVLN-------------TGVSGAIG---------GSSHV
MAV_4827|M.avium_104 VPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQP-------VQPPV
MLBr_01556|M.leprae_Br4923 MRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKE
Mb0767|M.bovis_AF2122/97 GGSGAAGSG----------APGGAGGAAG----LWGTGGAG---------
Rv0746|M.tuberculosis_H37Rv GGSGAAGSG----------APGGAGGAAG----LWGTGGAGGAGGSSAGG
MMAR_3326|M.marinum_M GGSGLAGR------------DGGAGGAAG----LWGTGGTGGAGGR-GGT
MUL_3062|M.ulcerans_Agy99 GGSAAATPG----------AAGGAGGAAG----LVGAGGAGGAGAN----
Mflv_5091|M.gilvum_PYR-GCK GGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-----
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-----
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIR
TH_3810|M.thermoresistible__bu GGN------------------GGHGGRGG----FLGIGGSGGWG------
MAB_4284c|M.abscessus_ATCC_199 GGAINES-------------LGGSGSVGG----STAVGG-----------
MAV_4827|M.avium_104 RVPQPPSPP----------QVGGTVPQSP--PQHQTPPGEGTPPKP----
MLBr_01556|M.leprae_Br4923 GADPAKIRG-------QLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLE
* .
Mb0767|M.bovis_AF2122/97 -------GAGGWLLGDGGAGGIGGASTVLG--------------------
Rv0746|M.tuberculosis_H37Rv GGAGGAGGAGGWLLGDGGAGGIGGASTVLG--------------------
MMAR_3326|M.marinum_M GGDGGAGGAGGWFSGDGGVGGIGGGSTAAGA-------------------
MUL_3062|M.ulcerans_Agy99 --------TGISNPGFGGAGGAGGAGAGAG--------------------
Mflv_5091|M.gilvum_PYR-GCK ------------TGGTGGQGG-LGGGGGTG--------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGQGG-LGGVGGTG--------------------
MSMEG_0868|M.smegmatis_MC2_155 ATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGT
TH_3810|M.thermoresistible__bu --------------GHGGNGGDTDADGGNG--------------------
MAB_4284c|M.abscessus_ATCC_199 -------------GAHTGVGGGVSTGVGVG--------------------
MAV_4827|M.avium_104 -------------DGPGNYGGGHVPTPGAG--------------------
MLBr_01556|M.leprae_Br4923 AVLLTADAALDLRANSGMEAQGVAIEAHLDR-------------------
. .
Mb0767|M.bovis_AF2122/97 ---GTGGGGGVGGLWGAGGAGGAGGTG--LVGGD-GGAGGAGGTGGLLAG
Rv0746|M.tuberculosis_H37Rv ---GTGGGGGVGGLWGAGGAGGAGGTG--LVGGD-GGAGGAGGTGGLLAG
MMAR_3326|M.marinum_M -TGGTGGTGGAGGLFGAGGNGGAGGAGTYFISAF-GGAGGTGGSGGLLSG
MUL_3062|M.ulcerans_Agy99 --GGVGEAGGAGGLLGAGGTGGGGGVAPSLVDGGTGGAGGAGGAGGLFGG
Mflv_5091|M.gilvum_PYR-GCK ---GQGGTGGTGGQGGTGGTGGTGGTG---------GTGGAGGDGGLGG-
Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGQGGTGGTGGTGGTG---------GTGGAGGDGGLGG-
MSMEG_0868|M.smegmatis_MC2_155 ATDGHGGSGINGGHGGNGGQGTIEANGPSAVASG-IGAGGNGGDGIDGG-
TH_3810|M.thermoresistible__bu ---GDGGNGGSAGRGGTGGLRGVFGIN-----------GGNGRAG-----
MAB_4284c|M.abscessus_ATCC_199 ---SHVGGGISESLGGSGSVGGSTAVG------------GGAHTGVGGGV
MAV_4827|M.avium_104 -----GSGGSGGGHVPTPGAGGSGGSG-----------GGHVPTPG----
MLBr_01556|M.leprae_Br4923 ---GRGPVATVLVQRGTLRIGDSVVAG--------DAYGRVRRMVDEHGV
.
Mb0767|M.bovis_AF2122/97 LIGAGGGHGGTGG--LNTNGDGGVGGAGGNAG-MLAGPGGAGGAGGDGEN
Rv0746|M.tuberculosis_H37Rv LIGAGGGHGGTGG--LSTNGDGGVGGAGGNAG-MLAGPGGAGGAGGDGEN
MMAR_3326|M.marinum_M LVGAGGGHGGAGGTAISNSGAGGAGGAGGDAG-LLGGPGGAGGTGGPGDF
MUL_3062|M.ulcerans_Agy99 IFGAGGGDGGAGGFTGGIDGAGGVGGAGGNTG-LLGGPGGSGGSGGDGIA
Mflv_5091|M.gilvum_PYR-GCK -LGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1 -LGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155 -LGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
TH_3810|M.thermoresistible__bu -LGGRGXXX----------XGGGVGAAVRSGN----GVFSGGG-------
MAB_4284c|M.abscessus_ATCC_199 STGVGVGSHVGGGISESLGGSGSVGGSTAVGG---GAHTGVGGGVN----
MAV_4827|M.avium_104 -TGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGG----
MLBr_01556|M.leprae_Br4923 DIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNAL
. . .
Mb0767|M.bovis_AF2122/97 -LDTGGDGGAGGS---AGLLFGSGGAGGAGGFG------FLGGDG-----
Rv0746|M.tuberculosis_H37Rv -LDTGGDGGAGGS---AGLLFGSGGAGGAGGFG------FLGGDG-----
MMAR_3326|M.marinum_M GTTHGGAGGAGGN---AGLLFGSGGTGGTGGYG------ASAGDG-----
MUL_3062|M.ulcerans_Agy99 KLGFNVDGGAGGAGVNGGFLFGSGGTGGFGGVGGVGTSTGIGGAG-----
Mflv_5091|M.gilvum_PYR-GCK GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155 QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
TH_3810|M.thermoresistible__bu ----GTPSAGFGVPTTIQFPAGSCTSRAVSREG------IMPSSR-----
MAB_4284c|M.abscessus_ATCC_199 ---TGVGVGSHVGGGISESLGGSGSVGGSTAVG------GGAHTS-----
MAV_4827|M.avium_104 --GHLPTPGAGTPGGGLGGFGGGHAPAPGGGLG-----------------
MLBr_01556|M.leprae_Br4923 AARSRKRISLEDLDSALKETSQLNLILKGDNAG------TVEALEEALMG
. *
Mb0767|M.bovis_AF2122/97 -GAGGNAGLLLSSGGAGGFGG-----------FGTAG--GVGGA--GGNA
Rv0746|M.tuberculosis_H37Rv -GAGGNAGLLLSSGGAGGFGG-----------FGTAG--GVGGA--GGNA
MMAR_3326|M.marinum_M -GHGGSAGLLFSGAGAGGAGG-----------VGLSGPGGAGGR--GGDA
MUL_3062|M.ulcerans_Agy99 -GRGGNAGLLFSDAGVGGFG-------------------GFGGT--GGNA
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
TH_3810|M.thermoresistible__bu -AASARAGAACASSTS-------------------------------RSR
MAB_4284c|M.abscessus_ATCC_199 -AINDALGGSGSVGGSTAVGG-------------------------GAHT
MAV_4827|M.avium_104 ---GGGGHAPAPGGGLGGFGG--------------------------GHS
MLBr_01556|M.leprae_Br4923 IQVDDEVALRVIDRGVGGITETN-------------VNLASASDAIIIGF
Mb0767|M.bovis_AF2122/97 GWLGFGGAGGIGGIGGNA--------NGGAGGNGGTGGQLWGSGGAGGEG
Rv0746|M.tuberculosis_H37Rv GWLGFGGAG-----------------------------------------
MMAR_3326|M.marinum_M GWLGDGGAGGTGGSSHYG--------DGGDGGAGGAAGQLSGGGGAGGQG
MUL_3062|M.ulcerans_Agy99 GWLGSGGSGGAGG-GSNG--------DGGAGGTGGSGGQIVGDGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
TH_3810|M.thermoresistible__bu RSFCCSRA------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAINESMNSSINASHSSS--------------------------------
MAV_4827|M.avium_104 GGGLGGLGGGHK--------------------------------------
MLBr_01556|M.leprae_Br4923 NVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLG
.
Mb0767|M.bovis_AF2122/97 GA----------ALSVGDTGGAGGVGGSAGL--------IGTGGNGGNG-
Rv0746|M.tuberculosis_H37Rv -----------------------GVGGSAGL--------IGTGGNGGNG-
MMAR_3326|M.marinum_M GQGNI-------AGAVTRTGGDGGAGGDAVL--------IGNGGNGGNGG
MUL_3062|M.ulcerans_Agy99 GQGD--------LLAAGGSGGDGGQGGDAVL--------IGTGGNGGNG-
Mflv_5091|M.gilvum_PYR-GCK G-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155 GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------MNESFGSSMGS
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSL
Mb0767|M.bovis_AF2122/97 --GTGAN-AGSPGTGGAGG--LLLGQNGLNGLP-----------------
Rv0746|M.tuberculosis_H37Rv --GTGAN-AGSPGTGGAGG--LLLGQNGLNGLP-----------------
MMAR_3326|M.marinum_M TDGTGAP-TGSPGAGGTGG--ILLGADGNDGLG-----------------
MUL_3062|M.ulcerans_Agy99 --ASGVL-AGIGGDGGSRG--LLLGEDGVNGEAAPPMTHIVLLGGDFPAA
Mflv_5091|M.gilvum_PYR-GCK SGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD---------------
Mvan_1264|M.vanbaalenii_PYR-1 SGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD----------------
MSMEG_0868|M.smegmatis_MC2_155 TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP---------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA--------
Mb0767|M.bovis_AF2122/97 --
Rv0746|M.tuberculosis_H37Rv --
MMAR_3326|M.marinum_M --
MUL_3062|M.ulcerans_Agy99 AS
Mflv_5091|M.gilvum_PYR-GCK --
Mvan_1264|M.vanbaalenii_PYR-1 --
MSMEG_0868|M.smegmatis_MC2_155 --
TH_3810|M.thermoresistible__bu --
MAB_4284c|M.abscessus_ATCC_199 --
MAV_4827|M.avium_104 --
MLBr_01556|M.leprae_Br4923 --