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MSYVIAAPEELATAARNLANISVTINAANANAILATTEVISPGADAVSAAITALINSHGLGYQSISQQTT AFHDRFMQTVNAAAASYTTTDLTAASLLKSMPAAVNAPAQALFGRPLIGNGSNGAPGTGAPGGDGGILFG SGGAGGSGAGGQDGGAGGRAGLFGNGGAGGAGGTGQTQGGAGGAGGLFFGNGGAGGPGGSGGLNGGAGGA GGVGGLLFGAGGAGGAGGTGTSGIGGLGGDGGSAGALSISAGGAGGNGGTGLSGFGGAGGAGGNAGLYGH GGGGGAGGTGTGMGVDNDGIGGAGGAGGSGGWLIGTGGTGGTGGFGDGPLGGQGGDGGNAGLFGVGGDGG LGGTGFFGVGGAGGAAGNAGLISGTGGVGGQGGVGGFGEGGAGGSGGGAGLIGNGGSGGTGGNAVGNSGV GGHGGAGGQGGRLYGNGGVGGNGGFSGPITAGGAGGTGGTGGSAGLFGDGGAGGAGGASGFASGGTGGIG GTGGLLFGAAGDGGNGGFGAGGRGGSGGAGGDAWLFGSGGSGGGGGAGAINDGGSGGAGGNGGRLFGDAG AGGSGGAGGTSFLDTVIVSSNGGAGGNGGSAGLVGNGGAGGAGGQGGLIVSADGNNGGAGGDGGGAGLLL GAGGAGGQGGLGGNTGDGGNGGNGGNAALIGDGGSGGAGGDAGSGDAGDGGDGGDARLVGSGGNGGNGGF SATPAAGGTGGAGGALFGSDGVAGLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3290 | - | - | 100% (726) | PE-PGRS family protein |
| M. marinum M | MMAR_5044 | - | 0.0 | 57.61% (769) | PE-PGRS family protein |
| M. marinum M | MMAR_1391 | - | 0.0 | 47.96% (882) | PE-PGRS family protein, PE_PGRS9 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 51.71% (818) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-140 | 47.74% (641) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0279c | PE_PGRS4 | 0.0 | 46.72% (869) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 7e-09 | 27.55% (294) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-48 | 31.80% (522) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-23 | 49.38% (160) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-122 | 43.40% (705) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 2e-43 | 34.22% (412) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1339 | - | 0.0 | 96.56% (726) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-135 | 44.87% (682) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3290|M.marinum_M --------------------------------------------------
MUL_1339|M.ulcerans_Agy99 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0279c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MMAR_3290|M.marinum_M ------------------MSYVIAAPEELATAARNLANISVTINAANAN-
MUL_1339|M.ulcerans_Agy99 ------------------MSYVIAAPEEFASAARNLANIGVTINAANAN-
Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGSVLGAADAA-
Rv0279c|M.tuberculosis_H37Rv ------------------MSFVIAAPEVIAAAATDLASLESSIAAANAA-
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLS-
MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADG------
MLBr_01556|M.leprae_Br4923 -------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAP-
MMAR_3290|M.marinum_M -------------------------------AILATTEVISPGADAVSAA
MUL_1339|M.ulcerans_Agy99 -------------------------------AILATTEVIQPGADAVSAA
Mb0767|M.bovis_AF2122/97 -------------------------------AAATTTGIVAAVQDEVSAA
Rv0279c|M.tuberculosis_H37Rv -------------------------------AAANTTALLAAGADEVSTA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------AVSAAQVGAVMPVVAESVASN
MAV_4827|M.avium_104 -------------------------------ATVEEDAIDVTGADDAATA
MLBr_01556|M.leprae_Br4923 ----------------------------VARRLRESFGGIKPAADKGAEQ
MMAR_3290|M.marinum_M ITALINSHG-------------LGYQSISQQTTAFHDRFMQTVNAAAASY
MUL_1339|M.ulcerans_Agy99 ITALINSHG-------------LGYQSISQQTTAFHDRFVQTVNAAAASY
Mb0767|M.bovis_AF2122/97 IAALFSAHG-------------RAYQVASAQAAAVHAQFVEALSAGAGAY
Rv0279c|M.tuberculosis_H37Rv VAALFGAHG-------------QAYQALSAQAQAFHAQFVQALTSGGGAY
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YGYQSQWVN--------------------------TGNPIHDLSGNLQNY
MAV_4827|M.avium_104 SAP---------------------------------DRVISAILGTREGA
MLBr_01556|M.leprae_Br4923 VATKAQAKR-----------------LGESLDQTLDRALDKAVAGNGATT
MMAR_3290|M.marinum_M TT-----------------------TDLT--------AASLLKSMPAAVN
MUL_1339|M.ulcerans_Agy99 TT-----------------------TDLT--------AASLLKSMPTAVN
Mb0767|M.bovis_AF2122/97 AS-----------------------AEAAGAAVLANPAQSVQQDLLAAVN
Rv0279c|M.tuberculosis_H37Rv AA-----------------------AEAA-----------ATSPLLAPIN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YA--------------------------------------AQPDGPSILS
MAV_4827|M.avium_104 AD---------------------------------------AGLQLSSIG
MLBr_01556|M.leprae_Br4923 AAP-----------------VQVDHSAAVVPIVAGEGPSTAHREELAPPA
MMAR_3290|M.marinum_M APAQALFGRPLIGNGSNGAPG-----TGAPGGDGGILFGSGGAGGSGAGG
MUL_1339|M.ulcerans_Agy99 APAQALFGRPLIGNGSNGTPG-----TGAPGGDGGILFGSGGAGGSGAGG
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Rv0279c|M.tuberculosis_H37Rv EFFLANTGRPLIGNGTNGAPG-----TGANGGDGGWLIGNGGAGGSGAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_4332|M.thermoresistible__bu --------MPFITSGAAFVGG-----------------------------
MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLS
MAV_4827|M.avium_104 VTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTA
MLBr_01556|M.leprae_Br4923 GQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNN
MMAR_3290|M.marinum_M Q---DGGAGGRAGLFGNGGAGGAGGTGQT----QGG--AGGAGGLFFGNG
MUL_1339|M.ulcerans_Agy99 Q---DGGAGGRAGLFGNGGAGGAGGTGQT----QGG--AGGAGGLFFGNG
Mb0767|M.bovis_AF2122/97 S-GLPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGG--AGGSGGWLLGTG
Rv0279c|M.tuberculosis_H37Rv VNGGAGGNGGAGGLIGNGGAGGAGGRASTGTGGAGG--AGGAAGMLFGAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_4332|M.thermoresistible__bu -----------------------------------------AAMLLAGPG
MAB_4284c|M.abscessus_ATCC_199 FGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINA
MAV_4827|M.avium_104 VLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGD----AAGQLSAMVA
MLBr_01556|M.leprae_Br4923 PFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRP
MMAR_3290|M.marinum_M GAGGPGGSGGLNGGAGGAGGVGG--LLFGAGGAGG---------------
MUL_1339|M.ulcerans_Agy99 GAGGPGGSGGLNGGAGGAGGVGG--LLFGAGGAGG---------------
Mb0767|M.bovis_AF2122/97 GVGGVGGLGAG---AGGAGGVGGAGGLLGAGGHGG---------------
Rv0279c|M.tuberculosis_H37Rv GVGGPGGFAAAFGATGGAGGAGGNGGLFADGGVGG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_4332|M.thermoresistible__bu GVSALEAAGSAPRTVEYEYSLVACDSTLPLMCEAG---------------
MAB_4284c|M.abscessus_ATCC_199 DHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVT--------------V
MAV_4827|M.avium_104 GLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLD---------------
MLBr_01556|M.leprae_Br4923 GGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRG-----------R
.
MMAR_3290|M.marinum_M AGGTGTSGIGGLGGDGG-----SAGALS----------------------
MUL_1339|M.ulcerans_Agy99 AGGSGTSGIGGLGGDGG-----SAGALS----------------------
Mb0767|M.bovis_AF2122/97 AGGLG-AVTGGVGGAGG-----AGGLL-----------------------
Rv0279c|M.tuberculosis_H37Rv AGGATDAGTGGAGGSGG-----NGGLFGAGGTGGPGGFGIFGGGAGGDGG
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPG-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPG-------------------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPG-------------------------
TH_4332|M.thermoresistible__bu ---------DSVGGLGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 VDDHSQRNTTNINDSFN---------------------------------
MAV_4827|M.avium_104 ---VSVAEEPETALARG---------------------------------
MLBr_01556|M.leprae_Br4923 PGGGGHGGGGRPGQRGG---------------------------------
.
MMAR_3290|M.marinum_M ----ISAGGAGGNGG----TGLSG-------FGGAGGAGGNAGLYGHGGG
MUL_1339|M.ulcerans_Agy99 ----ISAGGAGGNGG----TGLSG-------FGGAGGAGGNAGLYGHGGG
Mb0767|M.bovis_AF2122/97 AGLLAGPGGAGGTGG----RGFLN-------DGGVGGAGGNAGLLFG--A
Rv0279c|M.tuberculosis_H37Rv SGGLFGAGGTGGSGG----TSIIN-------VGGNGGAGGDAGMLSLGAA
Mflv_5091|M.gilvum_PYR-GCK -----KAGDAGGAG----AVGAAG-------AAGTVGTAGATGGTGTGAN
Mvan_1264|M.vanbaalenii_PYR-1 -----AAGAAGGAG----AIGTAG-------VAGAAGTAGATGGTGVGGN
MSMEG_0868|M.smegmatis_MC2_155 -----KGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGN
TH_4332|M.thermoresistible__bu --------------------------------ASHDRSAFSASALGMASF
MAB_4284c|M.abscessus_ATCC_199 -----TDRSTN--------------------IGSGNTTNTEIGSHNQANI
MAV_4827|M.avium_104 --------------------------------AALAAANAPLFASSTAAL
MLBr_01556|M.leprae_Br4923 -----AAGAFGRPGGAPRRGRKSK--------RQKRQEYDSMQAPVVGGV
MMAR_3290|M.marinum_M GGAGGTGTGM--GVDNDGIGGAGGAGGSGGWLIGTGGTGGTG--------
MUL_1339|M.ulcerans_Agy99 GGAGGTGTGM--GVDNDGIGGAGGAGGAGGWLIGTGGTGGTG--------
Mb0767|M.bovis_AF2122/97 GGTGGSG-----GAGLGGDGGAGGAGGNAGVLFGNAGSGGTG--------
Rv0279c|M.tuberculosis_H37Rv GGAGGSG-----GSNPDGGGGAGGIGGDGGTLFGSGGAGGVC--------
Mflv_5091|M.gilvum_PYR-GCK GGAGGVG-----GVGGTGAAGAAGGAGGLGETGTTGGAGGVG--------
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAG-----GIGGTGAAGAAGQAGTAGETGVTGGVGGIG--------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNN
TH_4332|M.thermoresistible__bu GPDWNPG------------GAFLGLIGPGGLLIGDGLN------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAG-------GSAAVGGNAGLAGNAGLAGNAGLAGNAG--------
MAV_4827|M.avium_104 AYAQDPG-----------TGAVDQYSLPDYLYVPVDPEPGDD--------
MLBr_01556|M.leprae_Br4923 RLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVT------
*
MMAR_3290|M.marinum_M ----------GFGDGPLGGQGGDG--GNAG--------LFGVGGDGG---
MUL_1339|M.ulcerans_Agy99 ----------GFGDGPLGGQGGDG--GNAG--------LFGVGGDGG---
Mb0767|M.bovis_AF2122/97 ----------GFG-DTDGGAGGAG--GDAG--------WLGSGGVGG---
Rv0279c|M.tuberculosis_H37Rv ----------GLG-FDAGGAGGAG--GKAGL-------LIGAGGAGG---
Mflv_5091|M.gilvum_PYR-GCK ------------GQGTAGGTGGVGGIGGAG----------STGAVGG---
Mvan_1264|M.vanbaalenii_PYR-1 ------------GQGTEGGTGGVGGVGGVG----------ATGGAGG---
MSMEG_0868|M.smegmatis_MC2_155 GAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSAT
TH_4332|M.thermoresistible__bu --------------GTDAYIDENGVFHEATR-----------GGNGG---
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGNAG-----------LAGNAG---
MAV_4827|M.avium_104 ----------ELAYSAVGEEDAESPTVVIEK--------LFLPEDSE---
MLBr_01556|M.leprae_Br4923 ------------ATQSVGDETLELLGSEMNYN-----VQVVSPEDEDREL
.
MMAR_3290|M.marinum_M ----LGGTG------------------------FFGVGGAGGAAGNAGLI
MUL_1339|M.ulcerans_Agy99 ----LGGTG------------------------FFGAGGAGGAAGNAGLI
Mb0767|M.bovis_AF2122/97 ----AGGFG------------------------ETGDGGVGGAGGKAGLL
Rv0279c|M.tuberculosis_H37Rv ----AGGGS------------------------FAGAGGTGGAGGAPGLV
Mflv_5091|M.gilvum_PYR-GCK ----VGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDA
Mvan_1264|M.vanbaalenii_PYR-1 ----VGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDA
MSMEG_0868|M.smegmatis_MC2_155 GADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDA
TH_4332|M.thermoresistible__bu --------------------------------LLWGNGGKGGNGLDAGLY
MAB_4284c|M.abscessus_ATCC_199 ---LAGNAG------------------------LAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 ----PRRRP-----------------------VLLVGSGLAVVGISAVLA
MLBr_01556|M.leprae_Br4923 LEPFDLTYG-------------------------EDQGDEDELQVRPPVV
..
MMAR_3290|M.marinum_M S--GTGG----------------VGGQGGVGGFG----------------
MUL_1339|M.ulcerans_Agy99 S--GTGD----------------VGGQGGVGGFG----------------
Mb0767|M.bovis_AF2122/97 --IGNGG----------------AGGAGVLIGNGG---------------
Rv0279c|M.tuberculosis_H37Rv GNAGNGGNGGASANGA--GAAGGAGGSGVLIGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK DSMGS------------------AGATGGKGGNGGNGGRGGLFG------
Mvan_1264|M.vanbaalenii_PYR-1 TSMGE------------------AGATGGKGGNGGNGGRGSLFG------
MSMEG_0868|M.smegmatis_MC2_155 LVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSS
TH_4332|M.thermoresistible__bu TVPDPDN-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAG----------------LAGNAGLAGNAG---------------
MAV_4827|M.avium_104 LEIALAIG---------------IRTTGTVALQPTP--------------
MLBr_01556|M.leprae_Br4923 TVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIG---------------
MMAR_3290|M.marinum_M ------------EGGAGGS----------------------GGGAGLIGN
MUL_1339|M.ulcerans_Agy99 ------------EGGAGGD----------------------GGGAGLIGN
Mb0767|M.bovis_AF2122/97 ------------NAGIGGT----------------------GPTAGDTGA
Rv0279c|M.tuberculosis_H37Rv ------------NGGSGGT----------------------GAPAGTAGA
Mflv_5091|M.gilvum_PYR-GCK ---------KGGNAGNGAD----------------------GGTGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 ---------RGGNAGNGGN----------------------GGTGGNGGN
MSMEG_0868|M.smegmatis_MC2_155 ATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGF
TH_4332|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------LAGNAGLAGN----------------------AGLAGNAGL
MAV_4827|M.avium_104 ------------NQHLIVP-----------------------TEQAPAPP
MLBr_01556|M.leprae_Br4923 ----------AYQVGVDLD-----------------------GSERLITF
MMAR_3290|M.marinum_M GGSGG-----------------------------------TGGNAVGN--
MUL_1339|M.ulcerans_Agy99 GGSGG-----------------------------------TGGNAVGN--
Mb0767|M.bovis_AF2122/97 GGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGT
Rv0279c|M.tuberculosis_H37Rv GGLGGQLLGRDGFNAPAST-PLHTLQQQILNAINEPTQALTGRPLIGNGA
Mflv_5091|M.gilvum_PYR-GCK GGTGG-TGGAGGTGG-------------------TGGTGGIGGAGSTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GGTGG-TGGNGGTGG-------------------TGGTGGIGGAGSTGGT
MSMEG_0868|M.smegmatis_MC2_155 NGTGGATGGRGGDGAGASV--WKANGQHSTGQTDTGGNGGRGGDGGTFVN
TH_4332|M.thermoresistible__bu -------------------------------------------PGSTIQM
MAB_4284c|M.abscessus_ATCC_199 AGNAG-----------------------------------LAGNAGLAGN
MAV_4827|M.avium_104 PVQAS-----------------------------------APQPKISVPE
MLBr_01556|M.leprae_Br4923 IDTPG--------------------------HEAFTAMRARGAKATDIAI
MMAR_3290|M.marinum_M SGVGGHGGAGGQGGRLYGNGGVGGNGGFSGPITAGGAGGTGG--------
MUL_1339|M.ulcerans_Agy99 SGVGGHGGAGGRGGRLYGNGGVGGNGGFSGPITAGGAGGTGG--------
Mb0767|M.bovis_AF2122/97 PGAVGSGATGAPGGWLLGDGGAGGSGAAGS-GAPGGAGGAAG-L------
Rv0279c|M.tuberculosis_H37Rv NGTPGTGADGGAGGWLFGNGGNGGHGATGADGGDGGSGGAGGIL------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GD
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GT
MSMEG_0868|M.smegmatis_MC2_155 AGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGN
TH_4332|M.thermoresistible__bu YFEASDGADGGRGGFLFGNGGDGGNG--------GNVGGKNG--------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAAVAG-NAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSS------
MAV_4827|M.avium_104 PVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP
MLBr_01556|M.leprae_Br4923 LVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTE
.
MMAR_3290|M.marinum_M --TGGSAG------------LFGDGGAGGAGGASGFAS-------GGTGG
MUL_1339|M.ulcerans_Agy99 --TGGSAG------------LPGDGGAGGAGGASGFAG-------GGTGG
Mb0767|M.bovis_AF2122/97 WGTGGAGGAGGW--------LLGDGGAGGIGGASTVLG--------GTGG
Rv0279c|M.tuberculosis_H37Rv SGIGGTGGSGGIG-------TTGQGGTGGTGGAALLIGS------GGTGG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGLGG
MSMEG_0868|M.smegmatis_MC2_155 GGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGG
TH_4332|M.thermoresistible__bu ----------------------ADPVTATVAADKSVAG--------GNGG
MAB_4284c|M.abscessus_ATCC_199 -HVGGAIN-------------ESLGGSGSVGGSTAVGG----------GA
MAV_4827|M.avium_104 VPVPVRIP------------VPDPVSPPQLLAPPRLSVP-------QPVQ
MLBr_01556|M.leprae_Br4923 YGLVAEDFGGDTMFID----ISAKVGTNIEALLEAVLLTADAALDLRANS
MMAR_3290|M.marinum_M IGGTGGLLFGAAGDGGNGGFG------------------AGGRGGSGG--
MUL_1339|M.ulcerans_Agy99 IGGTGGLPFGAAGDGGNGGFG------------------AGGRGGSGG--
Mb0767|M.bovis_AF2122/97 GGGVGGL-WGAGGAGGAGGTGL-----------------VGGDGGAGG--
Rv0279c|M.tuberculosis_H37Rv SGGFG---LDTGGAGGRGGD-------------------AGLFLGAAG--
Mflv_5091|M.gilvum_PYR-GCK TGGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-L
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-L
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTL
TH_4332|M.thermoresistible__bu NGGRGGLLFGLGGNGGNGGWST----------------------------
MAB_4284c|M.abscessus_ATCC_199 HTGVGGGVSTGVGVGSHVGGG-----------------------------
MAV_4827|M.avium_104 PPVRVPQPPSPPQVGGTVPQSP----------------------------
MLBr_01556|M.leprae_Br4923 GMEAQGVAIEAHLDRGRGPVAT----------------------------
.
MMAR_3290|M.marinum_M --AGG--------------------------DAWLFGSGGSGGGGGAGAI
MUL_1339|M.ulcerans_Agy99 --AGG--------------------------DAWLFGSGGSGGSGGAGAI
Mb0767|M.bovis_AF2122/97 --AGGTGGL----------------------LAGLIGAGG--GHGGTGGL
Rv0279c|M.tuberculosis_H37Rv --TGGQAAL----------------------SQNFIGAGGTAGAGGTGGL
Mflv_5091|M.gilvum_PYR-GCK GGGGGTG-----------------------GQGGTGGTGGQGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTG-----------------------GTGGTGGTGGQGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTI
TH_4332|M.thermoresistible__bu -------------------------------TSYLDARGGNGGNGGLGGV
MAB_4284c|M.abscessus_ATCC_199 ------------------------------ISESLGGSGSVGGSTAVGGG
MAV_4827|M.avium_104 --------------------------------PQHQTPPGEGTPPKPDGP
MLBr_01556|M.leprae_Br4923 -------------------------------VLVQRGTLRIGDSVVAGDA
.
MMAR_3290|M.marinum_M NDGGSG------GAGGNGGR-----LFGDAGAGGSG---GAGGTSFLDTV
MUL_1339|M.ulcerans_Agy99 NDGGSG------GAVGNGGR-----LFGDAGAGGSG---GAGGTSFLDTV
Mb0767|M.bovis_AF2122/97 NTNGDG------GVGGAGGN-----AGMLAGPGGAG---GAGGDG--ENL
Rv0279c|M.tuberculosis_H37Rv FANG--------GAGGAGG------FGANGGTGGNGLLFGAGGTG--GAG
Mflv_5091|M.gilvum_PYR-GCK GGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1 GGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG
MSMEG_0868|M.smegmatis_MC2_155 EANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGT
TH_4332|M.thermoresistible__bu LRPG-----------------------------------GLLSLLLPSGA
MAB_4284c|M.abscessus_ATCC_199 AHTGVG------GGVSTG--------VGVGSHVGGGISESLGGSGSVGGS
MAV_4827|M.avium_104 GNYG----------------------------GGHVPTPGAGGSGGSGGG
MLBr_01556|M.leprae_Br4923 YGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQ
.
MMAR_3290|M.marinum_M IVSSNG----GAGGNGG----------SAGLVGN-------GGAGGAGGQ
MUL_1339|M.ulcerans_Agy99 IVSSNG----GAAGNGG----------SAGLVGN-------GGAGGAGGQ
Mb0767|M.bovis_AF2122/97 DTGGDG----GAGGSAGLLF----GSGGAGGAGG---FGFLGGDGGAGGN
Rv0279c|M.tuberculosis_H37Rv TLGADG----GAGGHGG-LF----GAGGTGGAGGS-SGGTFGGNGGSGGN
Mflv_5091|M.gilvum_PYR-GCK AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN
TH_4332|M.thermoresistible__bu ASEPGG-----------------------------------LFTGGNGGN
MAB_4284c|M.abscessus_ATCC_199 TAVGGG-----------------------------------AHTGVGGGV
MAV_4827|M.avium_104 HVPTPG-------------------------------------AGGSGGS
MLBr_01556|M.leprae_Br4923 IADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEA
. .
MMAR_3290|M.marinum_M GGLIVS-------AD---------GNNGGAGGDGGGAGLLLGAG------
MUL_1339|M.ulcerans_Agy99 GGLIVS-------AD---------DNNGGAGGDGGGAGLLLGAG------
Mb0767|M.bovis_AF2122/97 AGLLLS----SGGAGGFGG----FGTAGGVGGAGGNAG-WLGFG------
Rv0279c|M.tuberculosis_H37Rv AGLLALG--ASGGAGGSGGSALNVGGTGGVGGNGGSGGSLFGFG------
Mflv_5091|M.gilvum_PYR-GCK GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1 GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155 GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA
TH_4332|M.thermoresistible__bu GGLAIAN--------------HWVGITDGVPGPDDDAVSSSAYG------
MAB_4284c|M.abscessus_ATCC_199 NTGVGVG-------------------SHVGGGISESLGGSGSVG------
MAV_4827|M.avium_104 GGGHVPTP--------------GTGGPGGTGGSGGGHVPTPGAG------
MLBr_01556|M.leprae_Br4923 LEEALMG-------IQVDDEVALRVIDRGVGGITETNVNLASAS------
* . .
MMAR_3290|M.marinum_M ----------GAGGQGGL--GGNTGDGGNG--------------------
MUL_1339|M.ulcerans_Agy99 ----------GAGGQGGL--GGNTVDGGNG--------------------
Mb0767|M.bovis_AF2122/97 ----------GAGGIGGI--GGN-ANGGAG--------------------
Rv0279c|M.tuberculosis_H37Rv ----------GAGGTGGS--SGIGSSGGTG--------------------
Mflv_5091|M.gilvum_PYR-GCK -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
Mvan_1264|M.vanbaalenii_PYR-1 -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
MSMEG_0868|M.smegmatis_MC2_155 AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSA
TH_4332|M.thermoresistible__bu ----------GHGGHGAG--------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------GSTAVGGG-AHTSAINDALG--------------------
MAV_4827|M.avium_104 ----------TPGGSGGG----HLPFPGAG--------------------
MLBr_01556|M.leprae_Br4923 -----DAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAID--------
MMAR_3290|M.marinum_M -----GNGGNAA-LIGDGGSGGAGGDA------------GSGDAGDGGDG
MUL_1339|M.ulcerans_Agy99 -----GNGGNAA-LIGDGGSGGAGGDG------------GSGDAGDGGAG
Mb0767|M.bovis_AF2122/97 -----GNGGTGGQLWGSGGAGGEGGAAL----------SVGDTGGAGGVG
Rv0279c|M.tuberculosis_H37Rv -----GDGGTAG-VFGNGGDGGAGGFG-------------ADTGGNSSSV
Mflv_5091|M.gilvum_PYR-GCK AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKG
Mvan_1264|M.vanbaalenii_PYR-1 AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 VAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG
TH_4332|M.thermoresistible__bu ----PGSGGNGGSAVANSLG--------------------NAIAGNGGDA
MAB_4284c|M.abscessus_ATCC_199 -----GSGSVGGSTAVGGGAHTSAIN-------------ESMNSSINASH
MAV_4827|M.avium_104 ----STPGGSGGGHLPTPGAGTPGG----------------GLGGFGGGH
MLBr_01556|M.leprae_Br4923 -DIEKALRGMLKPIYEENQLGRAEIRALFRSSKVG--IIAGCIISSGVVR
. . .
MMAR_3290|M.marinum_M GDARL--------VGSGGNGGNGG----FSATPAAGGTGGAGG--ALFGS
MUL_1339|M.ulcerans_Agy99 GDARL--------VGSGGNGGNGG----FSATPAAGGTGDAGG--AVFGS
Mb0767|M.bovis_AF2122/97 GSAGL--------IGTGGNGGNGG----TGANAGSPGTGGAGG--LLLGQ
Rv0279c|M.tuberculosis_H37Rv PNAVL--------IGNGGNGGNGG----KAG--GTPGAGGTSG--LIIGE
Mflv_5091|M.gilvum_PYR-GCK GAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1 GDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155 GDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGT
TH_4332|M.thermoresistible__bu GRFVL--------IGPGGNGGNGGTGLXXXPRPRRRRNHRRTRRRPNGRR
MAB_4284c|M.abscessus_ATCC_199 SSSMN--------ESFGSSMGSHG-----AAGTGFEAQGHAQGHASETAH
MAV_4827|M.avium_104 APAPG-----------GGLGGGGG-----HAPAPGGGLGGFGGGHSGGGL
MLBr_01556|M.leprae_Br4923 RNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKE
.
MMAR_3290|M.marinum_M DGVAGLP--------
MUL_1339|M.ulcerans_Agy99 DGVAGLP--------
Mb0767|M.bovis_AF2122/97 NGLNGLP--------
Rv0279c|M.tuberculosis_H37Rv NGLNGL---------
Mflv_5091|M.gilvum_PYR-GCK GGAAGDSDD------
Mvan_1264|M.vanbaalenii_PYR-1 GGAAGDSD-------
MSMEG_0868|M.smegmatis_MC2_155 AGTTGANNP------
TH_4332|M.thermoresistible__bu PRPPPGR--------
MAB_4284c|M.abscessus_ATCC_199 TTLPGAEHH------
MAV_4827|M.avium_104 GGLGGGHK-------
MLBr_01556|M.leprae_Br4923 GDVIESYELVEKQRA