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SLGMADVPDAPPDAGRILLSRARRECDPVMRVAVGWLAEPLATMAGYHLGWWDVNGSGTGGWSGRATRAA LVVGAAAACGDASAAAPVAAAVELMHNFSLVHDDVMDRDVTRRGRATVWTVWGETSAIMLGDALHVLCSR VLAEMLAPEVAMTAIATLESSFLGLRVGQVDDGDFETPKRVTVDGYLRMAAGKTAGLMGCACELGALTAG ADPLTVSAMREFGYHLGLAFQILDDIVGIWGDPSVTGKPVGSDLARRKKTLPVIAALESGSSAALKLAEL YRSTAPMTANDVAWASELIEAAGGRKAARRHADELMDAALTALPDQPGSADLIGLAQLVIGRDV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3212 | idsB_2 | - | 100% (345) | polyprenyl synthetase IdsB_2 |
| M. marinum M | MMAR_3219 | idsB_1 | e-138 | 70.93% (344) | polyprenyl synthetase IdsB_1 |
| M. marinum M | MMAR_0282 | idsB_3 | e-110 | 61.96% (326) | polyprenyl synthetase IdsB_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3415c | idsB | 1e-105 | 57.10% (345) | polyprenyl synthetase IdsB |
| M. gilvum PYR-GCK | Mflv_5253 | - | 2e-28 | 34.46% (267) | trans-hexaprenyltranstransferase |
| M. tuberculosis H37Rv | Rv3383c | idsB | 1e-105 | 57.10% (345) | polyprenyl synthetase IdsB |
| M. leprae Br4923 | MLBr_02277 | - | 2e-26 | 31.32% (265) | polyprenyl diphosphate synthase component |
| M. abscessus ATCC 19977 | MAB_1992c | - | 1e-24 | 34.57% (269) | polyprenyl synthetase |
| M. avium 104 | MAV_4581 | - | 2e-28 | 34.21% (266) | polyprenyl synthetase |
| M. smegmatis MC2 155 | MSMEG_1133 | - | 4e-27 | 33.08% (266) | bifunctional short chain isoprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_1767 | - | 9e-27 | 33.08% (266) | bifunctional short chain isoprenyl diphosphate synthase |
| M. ulcerans Agy99 | MUL_3197 | idsB | 2e-78 | 48.51% (336) | polyprenyl synthetase IdsB |
| M. vanbaalenii PYR-1 | Mvan_0992 | - | 4e-27 | 33.83% (266) | trans-hexaprenyltranstransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5253|M.gilvum_PYR-GCK MRTPANVVAGVDFGDAQFAQDVRDGVARIEALMSEELGRADALMSEAVNH
Mvan_0992|M.vanbaalenii_PYR-1 ------MVAGVDFGDAEFAQDVRDGVARIEALMSEELGKADVLMAEAVQH
MSMEG_1133|M.smegmatis_MC2_155 ------MVAGVDFGDPAFAADVRDGVARIEDLMSDELGKADELMAEAVQH
TH_1767|M.thermoresistible__bu ------VVAGVDLGDPDFAAGVRDGVARIEDLMSSELGKADDLMAEAVQH
MLBr_02277|M.leprae_Br4923 -----MVVAGINFGDAAFAATVQDRVVRIEQLMDAELRDTDEVMTESVLH
MAV_4581|M.avium_104 ----------MDFGDPAFAATVRDGVGRIEQLMDTELRSADDIMTELLTH
Mb3415c|M.bovis_AF2122/97 --MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLAT
Rv3383c|M.tuberculosis_H37Rv --MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLAT
MUL_3197|M.ulcerans_Agy99 ------MTADGTCESDVPAAVVQLFLSSARAACDPVLRRAVESMPEPLAT
MMAR_3212|M.marinum_M ------MSLGMADVPDAPPDAGRILLSRARRECDPVMRVAVGWLAEPLAT
MAB_1992c|M.abscessus_ATCC_199 ------------------------------------MLRGGKRLRPAFAY
: : .
Mflv_5253|M.gilvum_PYR-GCK LF--------------QAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVI
Mvan_0992|M.vanbaalenii_PYR-1 LF--------------QAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVI
MSMEG_1133|M.smegmatis_MC2_155 LF--------------QAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVI
TH_1767|M.thermoresistible__bu LF--------------RAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVI
MLBr_02277|M.leprae_Br4923 LF--------------AAGGKRFRPLFTVLSAQIGPRPDAPEVIIAGAVI
MAV_4581|M.avium_104 LF--------------KAGGKRFRPLFTVLSAQIGPDPDAAEVTIAGAVI
Mb3415c|M.bovis_AF2122/97 MAGYHLGWWNADRSTAAGSSGKYFRAALVYAAAAACGGDVGDATPVSAAV
Rv3383c|M.tuberculosis_H37Rv MAGYHLGWWNADRSTAAGSSGKYFRAALVYAAAAACGGDVGDATPVSAAV
MUL_3197|M.ulcerans_Agy99 MAGYYLGWWDIDRSALAGSSGTFVRAALVWAAAAACGGDAGNAAPIAAAV
MMAR_3212|M.marinum_M MAGYHLGWWDVNGSGTGGWSGRATRAALVVGAAAACG-DASAAAPVAAAV
MAB_1992c|M.abscessus_ATCC_199 WG--------------------------WRAITDDPDPWNPEVLRVCAAL
. . *.:
Mflv_5253|M.gilvum_PYR-GCK ELVHLATLYHDDVMDEAQVRRGAPSANARWG----------------NNI
Mvan_0992|M.vanbaalenii_PYR-1 ELVHLATLYHDDVMDEAQVRRGAPSANARWS----------------NNI
MSMEG_1133|M.smegmatis_MC2_155 ELVHLATLYHDDVMDEAQMRRGAQSANARWG----------------NNI
TH_1767|M.thermoresistible__bu ELVHLATLYHDDVMDDAEMRRGAPSANAKWG----------------NSI
MLBr_02277|M.leprae_Br4923 ELVHLASLYHDDVMDEAEVRRGAPSANLRWS----------------NSV
MAV_4581|M.avium_104 ELVHLATLYHDDVMDEAEVRRGTPTANVRWG----------------NNV
Mb3415c|M.bovis_AF2122/97 ELVHNFTLLHDDVMDGDATRRGRPTVWSVWG----------------VGG
Rv3383c|M.tuberculosis_H37Rv ELVHNFTLLHDDVMDGDATRRGRPTVWSVWG----------------VGV
MUL_3197|M.ulcerans_Agy99 ELVHSGTLLHDDVMAGEVTRGGRRAVWSIWG----------------IDN
MMAR_3212|M.marinum_M ELMHNFSLVHDDVMDRDVTRRGRATVWTVWG----------------ETS
MAB_1992c|M.abscessus_ATCC_199 ELLHTCALIHDDVIDSSATRRGEPTIHVEFAALHRENGWSGSPEQFGISA
**:* :* ****: * * : :.
Mflv_5253|M.gilvum_PYR-GCK AILAGDYLFATASRLTSRLG------PEAVRIIADTFALLVTGQMRETRG
Mvan_0992|M.vanbaalenii_PYR-1 AILAGDYLFATASRLVSRLG------PDAVRIIADTFALLVTGQMRETRG
MSMEG_1133|M.smegmatis_MC2_155 AILAGDYLFATASRLVSRLG------PDAVRVIADTFAQLVTGQMRETRG
TH_1767|M.thermoresistible__bu AILAGDYLFATASRLVSRLG------PEAVRVIADTFAQLVTGQMRETRG
MLBr_02277|M.leprae_Br4923 AILAGDYLFATASRLVSQLG------LDAVRIIADTFAQLVTGQMRETRG
MAV_4581|M.avium_104 AILAGDYLFATASRLVSRLG------PEAVQLIAETFAQLVTGQMRETRG
Mb3415c|M.bovis_AF2122/97 AILLGDALHATAVRILTGLTD-ECVAVRAIRRLQMSCLDLCIGQFEDCLL
Rv3383c|M.tuberculosis_H37Rv AILLGDALHATAVRILTGLTD-ECVAVRAIRRLQMSCLDLCIGQFEDCLL
MUL_3197|M.ulcerans_Agy99 AILLGDALQTAAIRTLTDLPD-PGVAVRAVMRLETSCLDLCIGRFEDCAF
MMAR_3212|M.marinum_M AIMLGDALHVLCSRVLAEMLA-PEVAMTAIATLESSFLGLRVGQVDDGDF
MAB_1992c|M.abscessus_ATCC_199 AILLGDLALTWADDMVVGAQLSPEAHVRARGVWSILRSEVLGGQYLDILS
**: ** . . * : *: :
Mflv_5253|M.gilvum_PYR-GCK AADQVDSVDHYLKVVYEKTA-CLISASGRFGATFSGSDEAQIERLAKLGG
Mvan_0992|M.vanbaalenii_PYR-1 AADHVDEVDHYLKVVYEKTA-CLIAASGRFGATFSGADDEQIERLARLGG
MSMEG_1133|M.smegmatis_MC2_155 AADHVDSVDHYLKVVYEKTA-CLIAASGRFGATFSGANDEQIERLSRLGG
TH_1767|M.thermoresistible__bu AADGADPIEHYLKVVYEKTA-CLISASGRFGATFSGADEEQVERLARLGG
MLBr_02277|M.leprae_Br4923 VPEGADSIEQYLKVVYEKTG-CLIGSAGRLGGLFAGAHAEQVERLSRLGS
MAV_4581|M.avium_104 RKEGSDPIEHYLKVVYEKTA-CLIAAAGRFGAMFSGADADQVERLSRLGG
Mb3415c|M.bovis_AF2122/97 EGQPEVTVDDYLRMAAGKTA-ALTGCCCALGALVANADDATIAALERFGH
Rv3383c|M.tuberculosis_H37Rv EGQPEVTVDDYLRMAAGKTA-ALTGCCCALGALVANADDATIAALERFGH
MUL_3197|M.ulcerans_Agy99 ECGQAGPVDSYERMAAGKTA-ALIGCCCGLGALAADAGDATITALERFGR
MMAR_3212|M.marinum_M ETPKRVTVDGYLRMAAGKTA-GLMGCACELGALTAGADPLTVSAMREFGY
MAB_1992c|M.abscessus_ATCC_199 ESSGDESVETALRVIRFKTAGYTVQRPLQLGVAIAGENAEISRLLGDVGL
:: :: **. :* :. : .*
Mflv_5253|M.gilvum_PYR-GCK IVGTAFQISDDIIDIDSDADESGKVPGTDLREGVHTLPVLYALRETGPDA
Mvan_0992|M.vanbaalenii_PYR-1 IVGTAFQISDDIIDIDSDPDESGKVPGTDLREGVHTLPVLYALRETGPDA
MSMEG_1133|M.smegmatis_MC2_155 IVGTAFQIADDIIDIDSDPDESGKTPGTDLREGVHTLPVLYALRETGPDA
TH_1767|M.thermoresistible__bu IVGTAFQISDDIIDIESESTESGKTPGTDLREGVHTLPVLYALRETGPEA
MLBr_02277|M.leprae_Br4923 IVGTAFQISDDIIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDS
MAV_4581|M.avium_104 IVGTAFQISDDIIDIDSDSHESGKLPGTDVREGVHTLPMVYALREPGPDA
Mb3415c|M.bovis_AF2122/97 ELGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAA
Rv3383c|M.tuberculosis_H37Rv ELGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAA
MUL_3197|M.ulcerans_Agy99 ELGLAFQCVN------------------DLGRRNATLTVAAALNSRSEAA
MMAR_3212|M.marinum_M HLGLAFQILDDIVGIWGDPSVTGKPVGSDLARRKKTLPVIAALESGSSAA
MAB_1992c|M.abscessus_ATCC_199 DIGIAFQLRDDVLGVFGDPKVTGKPAGDDLRSGKRTVLLAEALRLARQRD
:* *** : *: *: : **.
Mflv_5253|M.gilvum_PYR-GCK DRLRELLAGPVT--DDA-DVAEALRLLRGSQGIRKAKETVIGYAQEAQRE
Mvan_0992|M.vanbaalenii_PYR-1 DRLRELLATPVT--DDG-DLAEALRLLRASDGITKAKETVAAYAREAEQE
MSMEG_1133|M.smegmatis_MC2_155 DRLRELLAGPIE--RDE-DVAEALALLRRSPGLTKAKETVASYAAQAREE
TH_1767|M.thermoresistible__bu ERLRELVSRPVE--DDA-DLAEALDLLRRSPGMAQATETVREYATEARSV
MLBr_02277|M.leprae_Br4923 ERLRALLAGPVD--NDA-EVVEALALLRASPGMARARQVLAHYADQASGE
MAV_4581|M.avium_104 ARLRELLVGPID--DDE-VVAEALTLLRASPGMAKAKQSLREYAAQAHRE
Mb3415c|M.bovis_AF2122/97 TELAALYQAPAA--MTASDVERATALVKVAGGGHVAQR---CADERIQAA
Rv3383c|M.tuberculosis_H37Rv TELAALYQAPAA--MTASDVERATALVKVAGGGHVAQR---CADERIQAA
MUL_3197|M.ulcerans_Agy99 IEPAALCHSGSF--MATGDIDRAATLVDVAAGRHAVQR---CADQRIQAT
MMAR_3212|M.marinum_M LKLAELYRSTAP--MTANDVAWASELIEAAGGRKAARR---HADELMDAA
MAB_1992c|M.abscessus_ATCC_199 SAAEDLLHSWIGTPLTDQQVAEMCSLIVDLGALGAVESRIEEHTHRALDQ
* : *: . .
Mflv_5253|M.gilvum_PYR-GCK LDQLPDVPGR-QALASLVDYTVNRHG
Mvan_0992|M.vanbaalenii_PYR-1 LGQLPAGPGR-QALATLVQYTINRHG
MSMEG_1133|M.smegmatis_MC2_155 LSHLPECPGR-QALAVLVDYTISREG
TH_1767|M.thermoresistible__bu LAQLPAGPGR-DALATLIDFTVNRHG
MLBr_02277|M.leprae_Br4923 LAQLPDGPSR-DALATLVDYTTNRHG
MAV_4581|M.avium_104 LDQLPDVPGR-RALQTLVDFTISRHG
Mb3415c|M.bovis_AF2122/97 IAALPDAVRS-PDLIALSQLICRREC
Rv3383c|M.tuberculosis_H37Rv IAALPDAVRS-PDLIALSQLICRREC
MUL_3197|M.ulcerans_Agy99 VAALPDAVRS-RDLIALSQLICCRER
MMAR_3212|M.marinum_M LTALPDQPGS-ADLIGLAQLVIGRDV
MAB_1992c|M.abscessus_ATCC_199 LAGADIADDARAALSDLVRLVSNRSA
: * * *