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LSITCVDTRAQRSARRIEQLYSTDAQFAAARPSTAVGIAISKSGLGLPQIIQTVMDGYPQRPALGQRATR VVTDPNTGRSSAQLLAEFETITYRELWNRTNALTNAFAAEALADRGQRVCVLGFASIDYATIDLALMLLG AVSVPLPTNAARAQLCHIVSETQPSLIASSTENLPDAISLVLSHRAPHRVVVFDYRPELDAHREALEAAR ARLAAIPVTVETLTAIIARGRTVRPAEADCGAQSADAPALLIYTSGSTGAPKGVVYTRNRVADFWRTSKA EVEATEQRTAPSITLNFMPMSHANGRQVLYGTLSNGGTAYFTARSDLSTLFDDLALVRPTELGFPPRIWD MLLERFGREVDRRLRDGTAEGADPGALKARVAADLRQVLLGGRYALAMMGSAPISEQMKASVESLLDLDV MEGYGSTEAGTVIINNEVQRPQVIDYKLVDVAELGYFLTDRPYPRGELLVKTRTLFSGYYRDPEDGAQVF DPDGFYRTGDIMAQVGPDRLAYLDRRNNVLKLSQGEFVAVSRLEAIFANSPLVRQIFVYANGARAYPLAV VVPTQDAQSRHGRAELKAELHTSLHRVAMSAGLAPYEIPRDFIVETTPFTPQNGLLTAIHKLARPHLTQR YGARLELLYTELADSQTRRLHRLRQTGGRLPALETIRRAAGALLGTETTEPRPEAHFKDLGGDSVSAVTF SNLLHDIYGFDVPVGVILGPATDLRALASHVESRRGAGWSGPSFASVHVPRATSVHAGDLKLAKFLDTKT LAAATSLPAADARARTVLLTGATGFLGRYLVLEWLRRLRAVGGKLICLVRAASDEQARVRLDTAFDSGDP QLPEHFRQLAVDRLEVLAGDKSEPGLGLDGPTWQRLADTVDLIVDPATLVNHVLSYRQLFAPNVAGTAEL LRLALTTKRKPYAYVSTVSVANQIEPSAFTEDADIREISRTRTIDDSFANGYTTSKWASEVLLREAHDLC GLPVTVFRCDMILADTSYAGQLNLADTFTRLMLSVAATGIAPASFYRLGPDGKRQPAHFDGLPVEFIAEA VATLGARRHDGFQVHHVANPHHDGVGLDEYVDWLVDAGCPIRRIPDYDEWLSRFETALHALPDRKRRHSL LPLLQNYREPAEPIRGGIAPAPRFRGAVRQAKIGRDNDIPHVGPAIIAKYASDLQLLGLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2936 | fadD9_1 | - | 100% (1180) | fatty-acid-CoA ligase FadD9_1 |
| M. marinum M | MMAR_2117 | fadD9 | 0.0 | 64.26% (1178) | fatty-acid-CoA ligase FadD9 |
| M. marinum M | MMAR_3972 | - | 2e-33 | 25.34% (1026) | non-ribosomal peptide synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2621 | fadD9 | 0.0 | 66.10% (1174) | fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_2962 | - | 1e-33 | 25.59% (590) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2590 | fadD9 | 0.0 | 66.18% (1174) | fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_00484 | fadD9 | 0.0 | 60.25% (1180) | putative acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2962 | - | 0.0 | 52.55% (1178) | fatty-acid-CoA ligase FadD |
| M. avium 104 | MAV_3471 | - | 0.0 | 60.97% (1176) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2956 | - | 0.0 | 60.68% (1175) | NAD dependent epimerase/dehydratase family protein |
| M. thermoresistible (build 8) | TH_1879 | fadD9 | 1e-157 | 57.03% (512) | PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-CoA |
| M. ulcerans Agy99 | MUL_1722 | - | 0.0 | 64.01% (1178) | fatty-acid-CoA ligase FadD9 |
| M. vanbaalenii PYR-1 | Mvan_2578 | - | 0.0 | 62.73% (1178) | thioester reductase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2936|M.marinum_M -----------MSITCVDTRAQR-SARRIEQLYSTDAQFAAARPSTAVGI
TH_1879|M.thermoresistible__bu -----------------------------------------------VGL
MSMEG_2956|M.smegmatis_MC2_155 --------------MTIETREDR-FNRRIDHLFETDPQFAAARPDEAISA
Mvan_2578|M.vanbaalenii_PYR-1 --------------MSTDTREDR-LARRIADLYATDPQFAAAAPDDAISH
Mb2621|M.bovis_AF2122/97 --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
Rv2590|M.tuberculosis_H37Rv --------------MS--INDQR-LTRRVEDLYASDAQFAAASPNEAITQ
MUL_1722|M.ulcerans_Agy99 --------------MSPITREER-LERRIQDLYANDPQFAAAKPVTAITA
MLBr_00484|M.leprae_Br4923 MWRQQSISHRKESVMSTITKQEKQLARRVDDLTANDPQFAAAKPDPAVAA
MAV_3471|M.avium_104 --------------MSTATHDER-LDRRVHELIATDPQFAAAQPDPAITA
MAB_2962|M.abscessus_ATCC_1997 -----------MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAE
Mflv_2962|M.gilvum_PYR-GCK ---------------------------MTAREFTVPAPFTVEERDNIVGA
:
MMAR_2936|M.marinum_M AISKSGLGLPQIIQTVMDGYPQRPALGQRATRVVTDPNTGRSSAQLLAEF
TH_1879|M.thermoresistible__bu SX------------------------------------------------
MSMEG_2956|M.smegmatis_MC2_155 AAADPELRLPAAVKQILAGYADRPALGKRAVEFVTD-EEGRTTAKLLPRF
Mvan_2578|M.vanbaalenii_PYR-1 AIDQPGTHLPVIVQTVLDGYAERPALGQRAVRFVTDPATGRTTTELLPRF
Mb2621|M.bovis_AF2122/97 AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
Rv2590|M.tuberculosis_H37Rv AIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRF
MUL_1722|M.ulcerans_Agy99 AIERPGLPLPQIIETVMTGYADRPALAQRSVEFVTDAGTGHTTLRLLPHF
MLBr_00484|M.leprae_Br4923 ALAQPGLRLPQIIQTALDGYAERPALGQRVAEFTKDPKTGRTSMELLPSF
MAV_3471|M.avium_104 ALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVTDAKTGRTSAQLLPRF
MAB_2962|M.abscessus_ATCC_1997 QVLRPGLHLSEAIAALMTGYAERPALGERARELVTD-QDGRTTLRLLPRF
Mflv_2962|M.gilvum_PYR-GCK VFTHERDDPDHVIFQRLVDG----------------------------KW
MMAR_2936|M.marinum_M ETITYRELWNRTNALTNAFAAEA--LADRGQRVCVLGFASIDYATIDLAL
TH_1879|M.thermoresistible__bu ------------------QARAR--LADR---------------------
MSMEG_2956|M.smegmatis_MC2_155 DTITYRQLAGRIQAVTNAWHNH---PVNAGDRVAILGFTSVDYTTIDIAL
Mvan_2578|M.vanbaalenii_PYR-1 ETITYAELSRRIHAVTAALT-----DVHPGDRVAVLGFTSIDYTTVDMAL
Mb2621|M.bovis_AF2122/97 ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
Rv2590|M.tuberculosis_H37Rv ETITYRELWARAGTLATALSAEP--AIRPGDRVCVLGFNSVDYTTIDIAL
MUL_1722|M.ulcerans_Agy99 ETISYGELWDRISALADVLSTEQ--TVKPSDRVCLLGFNSVDYATIDMTL
MLBr_00484|M.leprae_Br4923 ETITYRQLGDRVGALARAWRHD---LLHAGYRVCVLGFNSVDYAIIDMAL
MAV_3471|M.avium_104 ETITYGEVAQRVSALGRALSDD---AVHPGDRVCVLGFNSVDYATIDMAL
MAB_2962|M.abscessus_ATCC_1997 DTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAI
Mflv_2962|M.gilvum_PYR-GCK IDVTARQAAGQIRSAARGLIAEG---VQAGDRVALLSATRYEWPILDFAI
MMAR_2936|M.marinum_M MLLGAVSVPLPTNAARAQLCHIVSETQPSLIASSTENLPDAISLVLSHRA
TH_1879|M.thermoresistible__bu ---------LP-----------------------------------AYMV
MSMEG_2956|M.smegmatis_MC2_155 LELGAVSVPLQTSAPVAQLQPIVAETEPKVIASSVDFLADAVALVESGPA
Mvan_2578|M.vanbaalenii_PYR-1 AMLGAVAVPLQTSAPATTVRPIVAETEPVVIASSVDALTDAVGLALDAPT
Mb2621|M.bovis_AF2122/97 IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
Rv2590|M.tuberculosis_H37Rv IRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEV-LAGHA
MUL_1722|M.ulcerans_Agy99 ARLGAVAVPLQTSAAITQLQPIVAETQPTMIAASVDALADATELALSGQT
MLBr_00484|M.leprae_Br4923 GVIGAVAVPLQTSAAITQLQSIVTETEPSMIATSVNQLPDTVELIL-SGQ
MAV_3471|M.avium_104 GAIGAVSVPLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQ
MAB_2962|M.abscessus_ATCC_1997 MILGGVAVPLQTSAPASQWTTILAEAEPNTLAVSIELIGAAMESVRATPS
Mflv_2962|M.gilvum_PYR-GCK LSIGAVTVPIYETSSAEQVQFVLADSGAVAAIAETDAHAAHIEAQRDTLP
:
MMAR_2936|M.marinum_M P-HRVVVFDYRPELDAHREALEAARARLAAIP--VTVETLTAIIAR----
TH_1879|M.thermoresistible__bu P-AAVVVLDR--------------------IP--LTVN------------
MSMEG_2956|M.smegmatis_MC2_155 P-SRLVVFDYSHEVDDQREAFEAAKGKLAGTG--VVVETITDALDR----
Mvan_2578|M.vanbaalenii_PYR-1 V-TRLVVFDHRAGVDDHRDALISASDRLRAANSPIEVETITDIVAR----
Mb2621|M.bovis_AF2122/97 P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
Rv2590|M.tuberculosis_H37Rv P-ARLVVFDYHGKVDTHREAVEAARARLAGS---VTIDTLAELIER----
MUL_1722|M.ulcerans_Agy99 A-TRVLVFDHHRQVDAHRAAVESARERLAGS---AVVETLAEAIARGDVP
MLBr_00484|M.leprae_Br4923 APAKLVVFDYHPEVDEQHDAVATARARLADSS--VVVESLTEVLGR----
MAV_3471|M.avium_104 APTRLVVFDYHPQVDDQREAVQDAAARLSGTG--VAVQTLAELLER----
MAB_2962|M.abscessus_ATCC_1997 I-KQVVVFDYTPEVDDQREAFEAASTQLAGTG--IAIETLDAVIAR----
Mflv_2962|M.gilvum_PYR-GCK ALRRIYVIDGSVP----------------------ALDELAEAGAS----
: *:* ::
MMAR_2936|M.marinum_M -GRTVRPAEADCGAQSADAPALLIYTSGSTGAPKGVVYTRNRVADFWRTS
TH_1879|M.thermoresistible__bu -GKLDR------------------------RALPAPEYQR---ADRYRAP
MSMEG_2956|M.smegmatis_MC2_155 -GRSLADAPLYVPDEA-DPLTLLIYTSGSTGTPKGAMYPESKTATMWQAG
Mvan_2578|M.vanbaalenii_PYR-1 -GSKLPVRAQFS-ADG-DALSLLIYTSGSTGAPKGAMYPQHLVANSWRRL
Mb2621|M.bovis_AF2122/97 -GRALPATPIADSAD--DALALLIYTSGSTGAPKGAMYRESQVMSFWRKS
Rv2590|M.tuberculosis_H37Rv -GRALPATPIADSAD--DALALLIYTSGSTGAPKGAMYRESQVMSFWRKS
MUL_1722|M.ulcerans_Agy99 RGASAGSAPGTDVSD--DSLALLIYTSGSTGAPKGAMYPRRNVATFWRKR
MLBr_00484|M.leprae_Br4923 -GKTLPATPIPVADDSADPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRS
MAV_3471|M.avium_104 -GKDLPAVAEPPADE--DSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRG
MAB_2962|M.abscessus_ATCC_1997 -GAALPAAPLYAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIRE
Mflv_2962|M.gilvum_PYR-GCK --VDAAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYEIRGA
. .
MMAR_2936|M.marinum_M KAEVEATEQRTAPSITLNFMPMSHANGRQVLYGTLSNGGTAYFTARSDLS
TH_1879|M.thermoresistible__bu ETAVEKTLT----------EIFAHVLG-----------------------
MSMEG_2956|M.smegmatis_MC2_155 SKARWDETLGVMPSITLNFMPMSHVMGRGILCSTLASGGTAYFAARSDLS
Mvan_2578|M.vanbaalenii_PYR-1 ARSFWGD-LGVFPAITLNFMPMSHVMGRGLLYGTLDAGGTAYFAARSDLS
Mb2621|M.bovis_AF2122/97 SGWFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYYVAKSDLS
Rv2590|M.tuberculosis_H37Rv SGWFEPS---GYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLS
MUL_1722|M.ulcerans_Agy99 T-WFEGG---YEPSITLNFMPMSHVMGRQILYGTLCNGGTAYFVVKSDLS
MLBr_00484|M.leprae_Br4923 DGNWFGP---TAASITLNFMPMSHVMGRGILYGTLGNGGTAYFAARSDLS
MAV_3471|M.avium_104 SKNWFGE---SAASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLS
MAB_2962|M.abscessus_ATCC_1997 DVMAGTEN---LPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYFAASSDMS
Mflv_2962|M.gilvum_PYR-GCK KACFPEH--LAKGEKLLVFLPLAHVLARALTIGAFSNGVTLGFT--SDIK
::* .
MMAR_2936|M.marinum_M TLFDDLALVRPTELGFPPRIWDMLLERFGREVDRRLRDGTAEGADPGALK
TH_1879|M.thermoresistible__bu ------------------------LERVG--VDDSFFD------------
MSMEG_2956|M.smegmatis_MC2_155 TFLEDLALVRPTQLNFVPRIWDMLFQEYQSRLDNRRAE-----GSEDRAE
Mvan_2578|M.vanbaalenii_PYR-1 TFLEDLALVRPTQLSFVPRIWDTIHAEVSQELERRPSD-----ATE----
Mb2621|M.bovis_AF2122/97 TLFEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD----GADRAALE
Rv2590|M.tuberculosis_H37Rv TLFEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVD----GADRAALE
MUL_1722|M.ulcerans_Agy99 TLFEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRLVD----GADRVALE
MLBr_00484|M.leprae_Br4923 TLLEDLKLVRPTELNFVPRIWETLYDESKRAVDRRLANS-GSA-DRAAIK
MAV_3471|M.avium_104 TLLEDLELVRPTELNFVPRIWETLYGEFQRQVERRLSEA-GDAGERRAVE
MAB_2962|M.abscessus_ATCC_1997 TLFEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASS--DTASAEAVA
Mflv_2962|M.gilvum_PYR-GCK NLVPMFAVFQPTLVVSVPRVFEKVYNTAELNAETGGKG------------
:
MMAR_2936|M.marinum_M ARVAADLRQVLLGGRYALAMMGSAPISEQMKASVESLL-DLDVMEGYGST
TH_1879|M.thermoresistible__bu -----------LGGDSISAMR--------AVAAINTAL-DTDVA------
MSMEG_2956|M.smegmatis_MC2_155 AAVLEEVRTQLLGGRFVSALTGSAPISAEMKSWVEDLL-DMHLLEGYGST
Mvan_2578|M.vanbaalenii_PYR-1 --VIADLRRSLLGGRYVTAMTGSAPLSPEMRAFVENLL-DVHLIDGYGST
Mb2621|M.bovis_AF2122/97 AQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGST
Rv2590|M.tuberculosis_H37Rv AQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGST
MUL_1722|M.ulcerans_Agy99 AQVKAEIRNDVLGGRYTSALTGSAPISDEMKAWVEELL-DMHLVEGYGST
MLBr_00484|M.leprae_Br4923 AEVMDEQRQSLLGGRYIAAMTGSAPTSPELKHGVESLL-EMHLLEGYGST
MAV_3471|M.avium_104 AEVLAEQRQYLLGGRFTFAMTGSAPISPELRNWVESLL-EMHLMDGYGST
MAB_2962|M.abscessus_ATCC_1997 AEVKADIRDNLFGGRVSAVMVGSAPLSEELGEFIESCF-ELNLTDGYGST
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M EAGTVIINNEVQRPQVIDYKLVDVAELGYFLTDRPYPRGELLVKTRTLFS
TH_1879|M.thermoresistible__bu --------------------------------------------VRTLF-
MSMEG_2956|M.smegmatis_MC2_155 EAGAVFIDGQIQRPPVIDYKLVDVPDLGYFATDRPYPRGELLVKSEQMFP
Mvan_2578|M.vanbaalenii_PYR-1 EAGAVFVDGRVQRPPVIDYKLVDVADLGYFSTDRPHPRGELLVKSETLFP
Mb2621|M.bovis_AF2122/97 EAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFP
Rv2590|M.tuberculosis_H37Rv EAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFP
MUL_1722|M.ulcerans_Agy99 EAGMILIDGAIRRPAVLDYKLVDVPDLGYFLTDRPHPRGELLVKTDSLFP
MLBr_00484|M.leprae_Br4923 EAGMVLFDGEVQRPPVIDYKLVDVPDLGYFSTDQPYPRGELLLKTQNMFP
MAV_3471|M.avium_104 EAGMVLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFP
MAB_2962|M.abscessus_ATCC_1997 EAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFL
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M GYYRDPEDGAQVFDPDGFYRTGDIMAQVGPDRLAYLDRRNNVLKLSQGEF
TH_1879|M.thermoresistible__bu --------------------------------------------------
MSMEG_2956|M.smegmatis_MC2_155 GYYKRPEITAEMFDEDGYYRTGDIVAELGPDHLEYLDRRNNVLKLSQGEF
Mvan_2578|M.vanbaalenii_PYR-1 GYYKRPDVTAEMFDEDGYYRTGDIVAETGADQLTYLDRRNNVLKLSQGEF
Mb2621|M.bovis_AF2122/97 GYYQRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEF
Rv2590|M.tuberculosis_H37Rv GYYQRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEF
MUL_1722|M.ulcerans_Agy99 GYYQRAEVTADVFDADGFYRTGDIMAEVGPEQFVYLDRRNNVLKLSQGEF
MLBr_00484|M.leprae_Br4923 GYYKRPEVTATVFDSDGYYQTGDIVAEVGPDRLVYVDRRNNVLKLAQGQF
MAV_3471|M.avium_104 GYYKRAETTAGVFDEDGYYRTGDVFAEIAPDRLVYVDRRNNVLKLAQGEF
MAB_2962|M.abscessus_ATCC_1997 GYYKRPEVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEF
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M VAVSRLEAIFANSPLVRQIFVYANGARAYPLAVVVPTQDAQSRHG--RAE
TH_1879|M.thermoresistible__bu --------------------------------------------------
MSMEG_2956|M.smegmatis_MC2_155 VTVSKLEAVFGDSPLVRQIYVYGNSARSYLLAVVVPTEEALSRWD--GDE
Mvan_2578|M.vanbaalenii_PYR-1 VTVSRLEAVFGNSPLVRQIYVYGNSARPYLLAVVVPTEAALA-----GAD
Mb2621|M.bovis_AF2122/97 IAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IEN
Rv2590|M.tuberculosis_H37Rv IAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHG--IEN
MUL_1722|M.ulcerans_Agy99 VTVSKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVPTQEALDAVP--VEE
MLBr_00484|M.leprae_Br4923 VTVAKLEAAFSNSPLVRQIYIYGNSAHPYLLAVVVPTEDALATND--IEV
MAV_3471|M.avium_104 VTLAKLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALASGD--PET
MAB_2962|M.abscessus_ATCC_1997 VAVATLEAEYANSPVVHQIYVYGSSERSYLLAVVVPTPEAVAAAKGDAAA
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M LKAELHTSLHRVAMSAGLAPYEIPRDFIVETTPFTPQNGLLTAIHKLARP
TH_1879|M.thermoresistible__bu ---------------------EAP--------------------------
MSMEG_2956|M.smegmatis_MC2_155 LKSRISDSLQDAARAAGLQSYEIPRDFLVETTPFTLENGLLTGIRKLARP
Mvan_2578|M.vanbaalenii_PYR-1 AKAAVAESLQDVAKATGLQSYEIPRDFLLETTPFTLENGLLTGIRKLARP
Mb2621|M.bovis_AF2122/97 LKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARP
Rv2590|M.tuberculosis_H37Rv LKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARP
MUL_1722|M.ulcerans_Agy99 LKARLGDSLQEVAKAAGLQSYEIPRDFIIETTPWTLQNGLLTGIRKLARP
MLBr_00484|M.leprae_Br4923 LKPLIIDSLQKVAKEADLQSYEVPRDLIVETTPFSLENGLLTGIRKLAWP
MAV_3471|M.avium_104 LKPKIADSLQQVAKEAGLQSYEVPRDFIIETTPFSLENGLLTGIRKLAWP
MAB_2962|M.abscessus_ATCC_1997 LKTTIADSLQDIAKEIQLQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARP
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M HLTQRYGARLELLYTELADSQTRRLHRLRQTGGRLPALETIRRAAGALLG
TH_1879|M.thermoresistible__bu ---------------------------------------TVRRLSRQLEG
MSMEG_2956|M.smegmatis_MC2_155 KLKAHYGERLEQLYTDLAEGQANELRELRRNGADRPVVETVSRAAVALLG
Mvan_2578|M.vanbaalenii_PYR-1 RLRERYGEQLEALYTMLSEEQADELRELRRSGGERPALETVGRAAGALLG
Mb2621|M.bovis_AF2122/97 QLKKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLG
Rv2590|M.tuberculosis_H37Rv QLKKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLG
MUL_1722|M.ulcerans_Agy99 QLKKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVLVTVCRAAAALLG
MLBr_00484|M.leprae_Br4923 KLKQHYGARLEQLYADLVEGQANALHVLKQSVANAPVLQTVSRAVGTILG
MAV_3471|M.avium_104 KLKQHYGERLEQMYADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLG
MAB_2962|M.abscessus_ATCC_1997 NLKAHYGPRLEQMYAEIAEQQAAELRALHGVDPDKPALETVLKAAQALLG
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M TETTEPRPEAHFKDLGGDSVSAVTFSNLLHDIYGFDVPVGVILGPATDLR
TH_1879|M.thermoresistible__bu GADTAP--------------------------------------------
MSMEG_2956|M.smegmatis_MC2_155 ASVTDLRSDAHFTDLGGDSLSALSFSNLLHEIFDVDVPVGVIVSPATDLA
Mvan_2578|M.vanbaalenii_PYR-1 TTAGELEPSAHFTDLGGDSLSALTFANLLRDIFDVDVPVGVIVSPATDLQ
Mb2621|M.bovis_AF2122/97 STAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLR
Rv2590|M.tuberculosis_H37Rv STAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLR
MUL_1722|M.ulcerans_Agy99 GSASDVQPDAHFTDLGGDSLSALSFTNLLHEIFDIDVPVGVIVSPANDLQ
MLBr_00484|M.leprae_Br4923 VATTDLPSNAHFTDLGGDSLSALTFGSLLRELFDIDVPVGVIVSPVNNLV
MAV_3471|M.avium_104 SAASDLSPDAHFTDLGGDSLSALTFGNLLREIFDVDVPVGVIVSPANDLA
MAB_2962|M.abscessus_ATCC_1997 VSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAANDLS
Mflv_2962|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2936|M.marinum_M ALASHVESRRGAGWSGPSFASVHVPR---ATSVHAGDLKLAKFLDTKTLA
TH_1879|M.thermoresistible__bu ---------QGADLGAVTYESVHGAT---ATEVRAADLTLDRFIDAATLR
MSMEG_2956|M.smegmatis_MC2_155 GVAAYIEGELR-GSKRPTYASVHG---RDATEVRARDLALGKFIDAKTLS
Mvan_2578|M.vanbaalenii_PYR-1 ALADYVESARRHGSVRPTFESVHGHSGRPGTEVHARDLTLDEFVDAATLA
Mb2621|M.bovis_AF2122/97 ALADHIEAAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAATLA
Rv2590|M.tuberculosis_H37Rv ALADHIEAAR-TGVRRPSFASIHGRS---ATEVHASDLTLDKFIDAATLA
MUL_1722|M.ulcerans_Agy99 ALADYVEAARKPGSSRPTFASVHGASNEQVTEVHAGDLSLDKFIDAATLA
MLBr_00484|M.leprae_Br4923 AIADYIERER-QGTKRPTFIAIHGRD---AGKVHASDLTLDKFIDVSTLT
MAV_3471|M.avium_104 AIASYIEAER-QGSKRPTFASVHGRD---ATVVRAADLTLDKFLDADTLA
MAB_2962|M.abscessus_ATCC_1997 GVAKFVDEQRYSGGTRPTAETVHGAG---HTEIRAADLTLDKFIDEATLH
Mflv_2962|M.gilvum_PYR-GCK -------------------------------------------------K
MMAR_2936|M.marinum_M AATSLPAADARARTVLLTGATGFLGRYLVLEWLRRLRAVGGKLICLVRAA
TH_1879|M.thermoresistible__bu TAADLPRPTGQVQTVLLTGATGFLGRYLLLEWLRRLRRVDDTVICLVRGR
MSMEG_2956|M.smegmatis_MC2_155 AAPGLPRSGTEIRTVLLTGATGFLGRYLALEWLERMDLVDGKVICLVRAR
Mvan_2578|M.vanbaalenii_PYR-1 HAPTLPGPRAEVRTVLLTGATGFLGRYLALEWLERMALVGGKLICLVRAK
Mb2621|M.bovis_AF2122/97 AAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLVRAR
Rv2590|M.tuberculosis_H37Rv AAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLVRAR
MUL_1722|M.ulcerans_Agy99 EAPRLPAANTQVRTVLLTGATGFLGRYLALEWLERMDLVDGKLICLVRAK
MLBr_00484|M.leprae_Br4923 AAPVLAQPGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALVRAK
MAV_3471|M.avium_104 SAPNLPKPATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALVRAR
MAB_2962|M.abscessus_ATCC_1997 AAPSLPKAVGIPHTVLLTGSNGYLGHYLALEWLERLDKTEGKLIAIVRGK
Mflv_2962|M.gilvum_PYR-GCK IFTAAANTAIEYSKALDSGGPGLV-----------LKLKHALFDKLVYGK
. . . ..* :*. * : : . :* .
MMAR_2936|M.marinum_M SDEQARVRLDTAFDSGDPQLPEHFRQLAVDRLEVLAGDKSEPGLGLDGPT
TH_1879|M.thermoresistible__bu SDADARQRLEAVFDT-DPALRRHFRELAAERLQVIAGDKGQPNLGLDVQT
MSMEG_2956|M.smegmatis_MC2_155 SDDEARARLDATFDTGDATLLEHYRALAADHLEVIAGDKGEADLGLDHDT
Mvan_2578|M.vanbaalenii_PYR-1 DDAAARVRLDSTFDSGDPELLRHYRRLAADHLEVIAGDKADADLGLDART
Mb2621|M.bovis_AF2122/97 SDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVT
Rv2590|M.tuberculosis_H37Rv SDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVT
MUL_1722|M.ulcerans_Agy99 SDTEARARLEKTFDSGAPELLAHYRALAGDHLEVLAGDKGEADLGLDRQT
MLBr_00484|M.leprae_Br4923 SNEDARARLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELDRQT
MAV_3471|M.avium_104 SDEEARARLDKTFDSGDPKLLAHYQQLAADHLEVIAGDKGEANLGLRQDV
MAB_2962|M.abscessus_ATCC_1997 NAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLDADT
Mflv_2962|M.gilvum_PYR-GCK LRAALGGRCHAAISGGAPLGARLGHFYRGVGLSIYEG-------------
* . .:. . : *.: *
MMAR_2936|M.marinum_M WQRLADTVDLIVDPATLVNHVLSYRQLFAPNVAGTAELLRLALTTKRKPY
TH_1879|M.thermoresistible__bu WRRLAERVDLIVDSAAFVNSVLPYRELFGPNVVGTAELIRFALTAKLKPY
MSMEG_2956|M.smegmatis_MC2_155 WQRLADTVDLIVDPAALVNHVLPYSQMFGPNALGTAELIRIALTTTIKPY
Mvan_2578|M.vanbaalenii_PYR-1 WQRLADTVDLIVDPAALVNHVLPYRQLFAPNVLGTAELLRIALTTRMKPF
Mb2621|M.bovis_AF2122/97 WQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKRKPY
Rv2590|M.tuberculosis_H37Rv WQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKRKPY
MUL_1722|M.ulcerans_Agy99 WQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAELLRLALTSKIKPY
MLBr_00484|M.leprae_Br4923 WRRLADTVDLIVDPAALVNHVLPYSELFGPNTLGTAELIRIALTSKQKPY
MAV_3471|M.avium_104 WQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQKPY
MAB_2962|M.abscessus_ATCC_1997 WQRLADTVDVIVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKIKPV
Mflv_2962|M.gilvum_PYR-GCK -YGLTETSAAITVNRVGDLRVGSVGKLVPGNSMRLGEDGELLVRGGVVFN
*:: *. . * . ::. * .* .: :
MMAR_2936|M.marinum_M AYVSTVSVANQIEPSAFTEDADIREISRTRTIDDSFANGYTTSKWASEVL
TH_1879|M.thermoresistible__bu NFVSTSDIGRQIEPDLFTEDADIRTISPTRTVDASYANGYGNSKWAGEVL
MSMEG_2956|M.smegmatis_MC2_155 VYVSTIGVGQGISPEAFVEDADIREISATRRVDDSYANGYGNSKWAGEVL
Mvan_2578|M.vanbaalenii_PYR-1 VYVSTIGVGAGIEPARFTEDADIRQISATRRIDDSYANGYGNSKWAGEVL
Mb2621|M.bovis_AF2122/97 IYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVL
Rv2590|M.tuberculosis_H37Rv IYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVL
MUL_1722|M.ulcerans_Agy99 SYTSTIGVADQIPPSAFTEDADIRVISATRAVDDSYANGYSNSKWAGEVL
MLBr_00484|M.leprae_Br4923 IYVSTIGVGNQIEPAKFTEDSDIRVISPTRNINNNYANGYGNSKWAGEVL
MAV_3471|M.avium_104 TYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAGEVL
MAB_2962|M.abscessus_ATCC_1997 TYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANGYGNSKWAGEVL
Mflv_2962|M.gilvum_PYR-GCK GYWGNEEETRAVFTDGWFHTGDLGAIDDD---------------------
: .. : . : . .*: :.
MMAR_2936|M.marinum_M LREAHDLCGLPVTVFRCDMILADTSYAGQLNLADTFTRLMLSVAATGIAP
TH_1879|M.thermoresistible__bu LREAHDLCGLPVAVFRSGMILVDPTYAGQLNVTDTVSRMVLSIVATGVAP
MSMEG_2956|M.smegmatis_MC2_155 LREAHDWCGLPVSVFRCDMILADTTYSGQLNLPDMFTRLMLSLVATGIAP
Mvan_2578|M.vanbaalenii_PYR-1 LREAHDLCGLPVSVFRCDMILADTTYAGQLNLPDMFTRLIFSLVATGVAP
Mb2621|M.bovis_AF2122/97 LREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAP
Rv2590|M.tuberculosis_H37Rv LREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAP
MUL_1722|M.ulcerans_Agy99 LREAHVLCGLPVAVFRCDMILADTTWAGQLNVPDMFTRMILSLAATGIAP
MLBr_00484|M.leprae_Br4923 LREAHDLCGLPVTVFRCDMILADTSYAGQLNVPDMFTRMMLSLAATGIAP
MAV_3471|M.avium_104 LREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRLMLSLVATGIAP
MAB_2962|M.abscessus_ATCC_1997 LREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIAP
Mflv_2962|M.gilvum_PYR-GCK ---------------------------GFLTIVGRKKEIIVTAGGKNVAP
* *.: . ..::.: ...:**
MMAR_2936|M.marinum_M ASFYRLGPDGKRQPAHFDGLPVEFIAEAVATLG---ARRHDG-----FQV
TH_1879|M.thermoresistible__bu KSFYRLGDDGSRQRAHFDGLPVDFVAEAVATLGWQIARTATGSPAGDFRT
MSMEG_2956|M.smegmatis_MC2_155 GSFYELDADGNRQRAHYDGLPVEFIAEAISTIGSQ---VTDG-----FET
Mvan_2578|M.vanbaalenii_PYR-1 ESFYHLATDGTRQRAHYDGLPVEFIAEAISTLGSD---VASG-----FRT
Mb2621|M.bovis_AF2122/97 GSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----FVT
Rv2590|M.tuberculosis_H37Rv GSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTH---SPDR-----FVT
MUL_1722|M.ulcerans_Agy99 GSFYELAADGARQRAHYDGLPVEFIAEAISTLGAQ---SQDG-----FHT
MLBr_00484|M.leprae_Br4923 GSFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQSLHDRDG-----FTT
MAV_3471|M.avium_104 GSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITDSDTG-----FQT
MAB_2962|M.abscessus_ATCC_1997 GSFYQAHATGERPLAHYDGLPGDFTAEAITTLGTQ---VVDS-----YET
Mflv_2962|M.gilvum_PYR-GCK AQLEDR-------------LRAHPLISQAMAVGDQ---------------
.: * . ::*
MMAR_2936|M.marinum_M HHVANPHHDGVGLDEYVDWLVD----AGCPIRRIPDYDEWLSRFETALHA
TH_1879|M.thermoresistible__bu YHVMNPHDDGIGIDEYVDWLIE----AGHPIERIDDFGEWLRRFEAGLHA
MSMEG_2956|M.smegmatis_MC2_155 FHVMNPYDDGIGLDEYVDWLIE----AGYPVHRVDDYATWLSRFETALRA
Mvan_2578|M.vanbaalenii_PYR-1 YHVMNPHDDGIGLDEYVDWLID----AGHPIRRVGDYPTWLQRFTVAITA
Mb2621|M.bovis_AF2122/97 YHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRA
Rv2590|M.tuberculosis_H37Rv YHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRA
MUL_1722|M.ulcerans_Agy99 YHVMNPYDDGIGLDEFVDWLNE----SGCPIQRIADYGDWLQRFETALRA
MLBr_00484|M.leprae_Br4923 YHVMNPHDDGIGMDEFVDWLID----AGCPIQRINDYDEWLRRFEISLRA
MAV_3471|M.avium_104 YHVMNPYDDGIGLDEYVDWLVD----AGYSIERIADYSEWLRRFETSLRA
MAB_2962|M.abscessus_ATCC_1997 YDCVNPHADGVSLDNFVDWLIE----AGYPIARIDNYTEWFTRFDTAIRS
Mflv_2962|M.gilvum_PYR-GCK -QPFIAALITVDTEAFPGWKERHHKASDASVADLADDPDLLAEIELAVKD
. . :. : : .* :. .: : : : .: .:
MMAR_2936|M.marinum_M LPDRKRRHSLLPLLQNYR------EPAEPIRGGIAPAPRFRGAVRQAKIG
TH_1879|M.thermoresistible__bu LPERQRQHSVLQMLTLLRQQGGEPQPPEPRHGSDAPADRFEAAVKRAGIN
MSMEG_2956|M.smegmatis_MC2_155 LPERQRQASLLPLLHNYQ------QPSPPVCGAMAPTDRFRAAVQDAKIG
Mvan_2578|M.vanbaalenii_PYR-1 LPERQRQASLLPLLHNYQ------HPETPIRGSIAPTDRFREAVQDAKIG
Mb2621|M.bovis_AF2122/97 LPDRQRHTSLLPLLHNYR------EPAKPICGSIAPTDQFRAAVQEAKIG
Rv2590|M.tuberculosis_H37Rv LPDRQRHASLLPLLHNYR------EPAKPICGSIAPTDQFRAAVQEAKIG
MUL_1722|M.ulcerans_Agy99 LPDRQRHSSLLPLLHNYR------QPERPVRGSIAPTDRFRAAVQEAKIG
MLBr_00484|M.leprae_Br4923 LPERQRHSSLLPLLHNYQ------KPEKPLHGSLAPTIRFRTAVQNANIG
MAV_3471|M.avium_104 LPDRQRQYSLLPLLHNYR------TPEKPINGSIAPTDVFRAAVQEAKIG
MAB_2962|M.abscessus_ATCC_1997 LPEKQKQHSLLPLLHAFE------QPSAAENHGVVPAKRFQHAVQAAGIG
Mflv_2962|M.gilvum_PYR-GCK ANQAVSKAEAIRKFRILP------VDFTEDTGELTPTLKVKRKVVAEKFA
: : . : : .*: .. * :
MMAR_2936|M.marinum_M RD-----NDIPHVGPAIIAKYASDLQLLGLA
TH_1879|M.thermoresistible__bu GG-----QGIPHVTPEVIVRYVTDLRQLGLL
MSMEG_2956|M.smegmatis_MC2_155 PD-----KDIPHVTADVIVKYISNLQMLGLL
Mvan_2578|M.vanbaalenii_PYR-1 PD-----KDIPHVTPQIVIKYVTDLQRLGLL
Mb2621|M.bovis_AF2122/97 PD-----KDIPHLTAAIIAKYISNLRLLGLL
Rv2590|M.tuberculosis_H37Rv PD-----KDIPHLTAAIIAKYISNLRLLGLL
MUL_1722|M.ulcerans_Agy99 PD-----KDIPHVGAPIIVKYVSDLRLLGLL
MLBr_00484|M.leprae_Br4923 QD-----KDIPHISPAIIAKYVSDLQLLGLV
MAV_3471|M.avium_104 PD-----KDIPHVSPPVIVKYITDLQLLGLL
MAB_2962|M.abscessus_ATCC_1997 PAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
Mflv_2962|M.gilvum_PYR-GCK AD--------------IEALYAKG-------
: * ..