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VAKDFRFGLSVRFIKSRAALQELAKRAEDLGFDILCVPDHLGAAAPFPTLTAAAMVTTKMRLSMYVLNAA FYKPALLSRDAEALDLLSEGRLELGLGTGYVREEFDAAELPYPSAGARVDYLEHMTAYLKQHHPTVPILI AGNGNRVMTLAAQQADIVGLTGSNVHGADDPLAERVDFVRRAAGDRFDALELNLAITALPNEGETAPDLA MTRRYAPELSDEQILALHSVLGGSPREIADTLAGYRDIYGVTSFTVQDNHLDNFAKVIAELR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4587 | - | - | 100% (272) | oxidoreductase |
| M. marinum M | MMAR_2775 | - | 3e-35 | 33.33% (309) | oxidoreductase |
| M. marinum M | MMAR_2559 | - | 3e-14 | 32.29% (192) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2917 | - | 3e-36 | 34.50% (313) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1815 | - | 7e-85 | 57.30% (274) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2893 | - | 3e-36 | 34.50% (313) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4277 | - | 1e-17 | 30.48% (292) | luciferase-like monooxygenase superfamily protein |
| M. avium 104 | MAV_1042 | - | 1e-123 | 77.57% (272) | hypothetical protein MAV_1042 |
| M. smegmatis MC2 155 | MSMEG_5592 | - | 8e-83 | 57.72% (272) | hypothetical protein MSMEG_5592 |
| M. thermoresistible (build 8) | TH_2824 | - | 6e-13 | 27.80% (295) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_4447 | - | 1e-85 | 98.73% (157) | hypothetical protein MUL_4447 |
| M. vanbaalenii PYR-1 | Mvan_4930 | - | 2e-82 | 56.20% (274) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2917|M.bovis_AF2122/97 -----------MTVASTAHHTRRLRFG--LAAPLPRAGTQMRAFAQAVEA
Rv2893|M.tuberculosis_H37Rv -----------MTVASTAHHTRRLRFG--LAAPLPRAGTQMRAFAQAVEA
MMAR_4587|M.marinum_M ---------------MAKD----FRFG--LSVRFIKSRAALQELAKRAED
MUL_4447|M.ulcerans_Agy99 ---------------MLTGRHLYFAYGSNLCVRQMSVRCPDASDPRPAVL
MAV_1042|M.avium_104 ---------------MAKD----FRFG--MSMRFYKSREALLDKAKRAED
Mflv_1815|M.gilvum_PYR-GCK MPLPPAVQTWTYDHDVAKE----FRFG--VGVTRVSTRAKLEDDARRAEA
Mvan_4930|M.vanbaalenii_PYR-1 ---------------MATE----FRFG--VGVTRARSRAELVDSARRAED
MSMEG_5592|M.smegmatis_MC2_155 --------------MMPKE----FRFG--VSVRNAESQAQVAATARRAED
MAB_4277|M.abscessus_ATCC_1997 -----------------------MDFRVFVEPQQGATYSDQLRVAQAAEE
TH_2824|M.thermoresistible__bu -----------------------MDFRVFVEPQQGGTYADQLAVARAAED
: : : .: .
Mb2917|M.bovis_AF2122/97 AGFDVLAFPDHLVPSVSPFAG-----------------ATAAAMATQRLH
Rv2893|M.tuberculosis_H37Rv AGFDVLAFPDHLVPSVSPFAG-----------------ATAAAMATQRLH
MMAR_4587|M.marinum_M LGFDILCVPDHLG-AAAPFP-----------------TLTAAAMVTTKMR
MUL_4447|M.ulcerans_Agy99 SDHDWLINERGVA-TVEPLTGGQVHGVLWQISDRDLATLDSAEGLPVRYR
MAV_1042|M.avium_104 AGFDILCVPDHLG-AAAPFP-----------------TLTAVAMVTTTLR
Mflv_1815|M.gilvum_PYR-GCK LGFDVLHVPDHLG-GSAPFP-----------------VMTAVAMATTSLR
Mvan_4930|M.vanbaalenii_PYR-1 LGFDVLHVPDHLG-GPAPFP-----------------VMTTIAMATTTLR
MSMEG_5592|M.smegmatis_MC2_155 LGYNVIVVPDHLG-APAPFP-----------------TLTAIAAATDTIR
MAB_4277|M.abscessus_ATCC_1997 LGFSAFFRSDHYLAMGGADGLPG--------PTDAWVTLGAIARETTAIR
TH_2824|M.thermoresistible__bu LGYSAFFRSDHYLAMSG-DGLPG--------PTDSWVTLAGIARETTSIR
... : . :
Mb2917|M.bovis_AF2122/97 TGTLVLN-------NDFRHPVDTAR---EAAGVATLAEGRFELGLGAGHR
Rv2893|M.tuberculosis_H37Rv TGTLVLN-------NDFRHPVDTAR---EAAGVATLAEGRFELGLGAGHR
MMAR_4587|M.marinum_M LSMYVLN-------AAFYKPALLSR---DAEALDLLSEGRLELGLGTGYV
MUL_4447|M.ulcerans_Agy99 RDLLCVRTHDGPTTAWVYIDHRITPGPPRPEYLNRVIDGALHHGLPQRWI
MAV_1042|M.avium_104 LSMYVLN-------SAFYKPALLSR---DMQALDLLSDGRLEIGLGTGYV
Mflv_1815|M.gilvum_PYR-GCK VGTFVLN-------SAFYRPALLAR---DVAALNDLSDGRVELGLGTGYV
Mvan_4930|M.vanbaalenii_PYR-1 VGTFVIN-------SAFYRPALLAR---DVAALHDLSEGRFELGLGTGYV
MSMEG_5592|M.smegmatis_MC2_155 VGTCVLN-------ACFYKPALLAR---DVTALRDLSDGRFEVGLGAGYV
MAB_4277|M.abscessus_ATCC_1997 LGTLVTS-------ATFRHPGPLAVT---VAQVDEMSSGRVDFGLGAGWF
TH_2824|M.thermoresistible__bu LGTLVTS-------ATFRYPGPLAIS---VAQVDEMSGGRVEFGLGSGWF
. . : : : * .. **
Mb2917|M.bovis_AF2122/97 R--SEYD--------------------AAGITFDSG---ATRVARLIESA
Rv2893|M.tuberculosis_H37Rv R--SEYD--------------------AAGITFDSG---ATRVARLIESA
MMAR_4587|M.marinum_M R--EEFD--------------------AAELPYP----------------
MUL_4447|M.ulcerans_Agy99 DFLHRWDPVHWLQPVSAAASGAGPQSLSALLSEPG-----------LSEI
MAV_1042|M.avium_104 R--EEFE--------------------AAEIPYP----------------
Mflv_1815|M.gilvum_PYR-GCK R--EEFD--------------------AAGIPYP----------------
Mvan_4930|M.vanbaalenii_PYR-1 K--EEFD--------------------AAGIPFP----------------
MSMEG_5592|M.smegmatis_MC2_155 R--EEFE--------------------AAELPFP----------------
MAB_4277|M.abscessus_ATCC_1997 S--EEHE--------------------AYAIPFPSLGERFDRLEEQLEIL
TH_2824|M.thermoresistible__bu E--PEHQ--------------------AYAIPFPPLGERFDRLTEQLEII
. : : :.
Mb2917|M.bovis_AF2122/97 HLIRALLDAEPVDFDGQHYRVHAEAGSLVAPPKVRVPLLVGGNG-TEVLR
Rv2893|M.tuberculosis_H37Rv HLIRALLDAEPVDFDGQHYRVHAEAGSLVAPPKVRVPLLVGGNG-TEVLR
MMAR_4587|M.marinum_M -------------SAGARVDYLEHMTAYLKQHHPTVPILIAGNG-NRVMT
MUL_4447|M.ulcerans_Agy99 SQLRSRFGFLAIHGGGARVDYLEHMTAYVKQHHPTVPILIAGNG-NRVMT
MAV_1042|M.avium_104 -------------SARERVDYLEHMTKYLKEHHPSTPLIIAGNG-DRVLT
Mflv_1815|M.gilvum_PYR-GCK -------------TAGERVDHLKLTAAHIAEHLPDVPIMIAGNG-DRVLR
Mvan_4930|M.vanbaalenii_PYR-1 -------------SARERVDHLKLTIEYMTEHLPDVPIMIAGNG-DRVLR
MSMEG_5592|M.smegmatis_MC2_155 -------------SARERIDHLRHTTEYLREHVSDVPIMVAGNG-DRLLT
MAB_4277|M.abscessus_ATCC_1997 TGLWTTPTGDTYSYAGKHYTVTDSPALPKPVQEPHPPIVIGGLGVKRTPA
TH_2824|M.thermoresistible__bu TGLWTTPSGEKYDFTGKHYTVVDSPGLPKPVQDPYPPIIIGGQGPKRTPA
: *:::.* * .
Mb2917|M.bovis_AF2122/97 LGGRIADIVGLAGISHNRDATQVRFTHFDADGLADRIAVVRHAAGDRFEA
Rv2893|M.tuberculosis_H37Rv LGGRIADIVGLAGISHNRDATQVRFTHFDADGLADRIAVVRHAAGDRFEA
MMAR_4587|M.marinum_M LAAQQADIVGLTGSN----------VHGADDPLAERVDFVRRAAGDRFDA
MUL_4447|M.ulcerans_Agy99 LAAQQANIVGLTGSN----------VHGADDPLAERVDFVRRAAGDRFDA
MAV_1042|M.avium_104 IAARNADIIGLTGAK----------VRDVEDPFAERVEFVRNAAGDRFDS
Mflv_1815|M.gilvum_PYR-GCK TAARFADIVGFTGGDR--------AATGDEDPLGDRIGFVRAAAGERFAA
Mvan_4930|M.vanbaalenii_PYR-1 IAARSADIIGFTGGDR--------AATADEDPLADRIAFVRDAAGERFGD
MSMEG_5592|M.smegmatis_MC2_155 VAAQTADIVGLTGGDG--------VPDGDHDPLAERISFLRKAADGR--D
MAB_4277|M.abscessus_ATCC_1997 LAARFATEFNLPFQP-----------VDVITDQYARVAHAVEAAGRPADS
TH_2824|M.thermoresistible__bu LAARFANEFNIPFVR-----------LDALKAQFERVAAAVAEAGREPDS
..: * ..:. *: *.
Mb2917|M.bovis_AF2122/97 IELNALIQAVVCTNDRNAAAAELAATLGGITPEQVLESPFLLLGTHEQMA
Rv2893|M.tuberculosis_H37Rv IELNALIQAVVCTNDRNAAAAELAATLGGITPEQVLESPFLLLGTHEQMA
MMAR_4587|M.marinum_M LELNLAITALPNEGETAPDLAMTRRYAPELSDEQILALHSVLGGSPREIA
MUL_4447|M.ulcerans_Agy99 LELNLAITALPNEGETAPDLAMTRRYAPELSDEQILALHSVLGGSPREIA
MAV_1042|M.avium_104 LELNLAITAMPRVGETEPDLKLTRSYSPELTDEQILSMPSVLSGSPRDIA
Mflv_1815|M.gilvum_PYR-GCK LELNIAITAIPLDSSGQPDLTIPRISLPGLSDDELLRHPSVLSGSTTEIA
Mvan_4930|M.vanbaalenii_PYR-1 LELNLAVTAMPVDDSGRPDLTIPRISLPGLSDEELLRHPGVLSGSVDEIA
MSMEG_5592|M.smegmatis_MC2_155 LELNITFTAIPAAGSEMPDLRLTRRFLGHLTDEQLLRHPGVLAGSASDMA
MAB_4277|M.abscessus_ATCC_1997 MTYSAAFALCIGDT----DADIARRAANIGREVEEITENSPLAGTPDAVA
TH_2824|M.thermoresistible__bu MIYSAAFVLCAGRD----DAEIARRAAAINREVDELRSNSPVVGTPAEIV
: . . : : : *: :.
Mb2917|M.bovis_AF2122/97 EALAARQRRFGVSYWTVFDEWAGRASAMRDIA-EVIALLRYG
Rv2893|M.tuberculosis_H37Rv EALAARQRRFGVSYWTVFDEWAGRASAMRDIA-EVIALLRYG
MMAR_4587|M.marinum_M DTLAGYRDIYGVTSFTVQDN------HLDNFA-KVIAELR--
MUL_4447|M.ulcerans_Agy99 DTLAGYRDIYGVTSFTVQDN------HLDNFA-KVIAELR--
MAV_1042|M.avium_104 DTLSAYRDKYGVSSFTVQDN------HIDNFA-KVIAELR--
Mflv_1815|M.gilvum_PYR-GCK DRIHGYRDVYGISYVIVQMR------HAEAFG-AVIDLLR--
Mvan_4930|M.vanbaalenii_PYR-1 DRIRGYRDVYGISYLIVQMR------HAEAFG-KVIELLR--
MSMEG_5592|M.smegmatis_MC2_155 DRLRQLRDTYGVSYFIVQIP------HIETFA-KVIAELR--
MAB_4277|M.abscessus_ATCC_1997 EKLSIYVD-AGVQRVYVQLLDIRDLDHLEFFASTVIPQFS--
TH_2824|M.thermoresistible__bu DRLGPFIE-AGVQRVYLQLLDMSDLDHLELIATQVVPQLR--
: : *: : :. *: :