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MSFAIVRPEWVTAAASDLAGIGSSVGAANAAAAGSTTAVLAAGADEVSAVIAGFFGAHAQEYQAISARVA TYHQQFVQSLNGSAGAYAAADAASASSLQTLMRDALNLINAPTNALLGRPLIGNGTNGAPGTGQAGGPGG ILWGNGGAGGSGAPGQTGGVGGAAGLFGNGGTGGAGGTGVTGTPGAAGESGGTGGTGGAGGLGGHGGLLF GNGGTGGAGGAGGTGGVGGQVNAEGVVGAGGPGGTGGVAGAGGAAGLFGSPGHAGIGGQTGTNGAAGGGG FGFREDFINNTGLPDNQIYVTEIGQTTPGHWAWIDQNGVAHPIDHNAADAPGHLTKDGVNYANMSFTLDQ AGNLTTPSEFQGGRVFISMKQPLYIAISPDNMGWAGPDPANPADPNYSTVYDWYEMTFNNGAIPFGGNTT QVDQFGFPFSVTVTQDSSGFAGTSGLTLSRAQVFQQFATTVPTEFQSLVVHDATGDPVRILSPRTAQPGG LSTWLDPSINDFWTTYQTNQFNYDGPGYTVQGSVNASDQFVYSVTPTGGSSTTYTMVKPTTAEVFAANGP FVGTAQQGAFLAELDAAFNRGVAISPDQWSNVADYYPTGGRWNNWAEFFHSDSINNLAYGFPFDDVNSQS SVLILDNSRPPTELVFNLGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2551 | - | - | 100% (650) | PE-PGRS family protein |
| M. marinum M | MMAR_2102 | - | 4e-92 | 58.12% (308) | PE-PGRS family protein |
| M. marinum M | MMAR_2033 | - | 9e-90 | 56.72% (305) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1487c | PE_PGRS28 | 1e-95 | 61.11% (306) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-45 | 53.85% (169) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 5e-96 | 61.51% (304) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-16 | 42.71% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 6e-22 | 36.28% (215) | hypothetical protein MAB_0321c |
| M. avium 104 | MAV_1346 | - | 1e-21 | 34.10% (261) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-32 | 45.60% (182) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 4e-26 | 34.31% (306) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 1e-86 | 53.47% (331) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_4739 | - | 1e-147 | 54.26% (470) | hypothetical protein Mvan_4739 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1487c|M.bovis_AF2122/97 ---------MSLVIVAPETVAAAALDVARIGSSIG---VANSAAAGSTTS
Rv1450c|M.tuberculosis_H37Rv ---------MSLVIVAPETVAAAALDVARIGSSIG---AANAAAAGSTTS
MUL_0572|M.ulcerans_Agy99 ---------MSYVVAIPDMLASAAADVAGIGSSVG---AANTAAVGATTG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_5091|M.gilvum_PYR-GCK ----MVTFGGGATPTPTSLGAAA---VDLSGTSCGLICNGQDGTGQNGGI
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M --------------------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 --------------------------------------------MDSVGH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 VLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYV
Rv1450c|M.tuberculosis_H37Rv VLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYV
MUL_0572|M.ulcerans_Agy99 VMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_5091|M.gilvum_PYR-GCK LFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAG
TH_4332|M.thermoresistible__bu ------------------------MPFITSGAAFVGGAAMLLAGPGGVSA
MMAR_2551|M.marinum_M ----MSFAIVR---------PEWVTAAASDLAGIGSSVGAANAAAAGSTT
Mvan_4739|M.vanbaalenii_PYR-1 IAWVGSLAVALGVAGAAASPPAISWAESSDSASQDTSAPDPGEASGDDTA
MLBr_01183|M.leprae_Br4923 ---MPLFLNAE---------PQALTAAANTLEGLSAATVASNAAAAQLTT
MAV_1346|M.avium_104 ---MS-FVTTR---------PEALLAVASMLEGLGSSMDAQNAAAAAPTT
Mb1487c|M.bovis_AF2122/97 SAEATNAAPLATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGA
Rv1450c|M.tuberculosis_H37Rv SAEATNAAPLATLEHNVLNALNAPTQALLGRPLIGDGAAGAPGTGQAGGA
MUL_0572|M.ulcerans_Agy99 AAEAANASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGLAGTGAAGGA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mflv_5091|M.gilvum_PYR-GCK AFALFGNGGNGGNGGVGVVGATGAVGAPGVAGATGATGVTSG---VVGGN
TH_4332|M.thermoresistible__bu LEAAGSAPRTVEYEYSLVACDSTLPLMCEAG-------------------
MMAR_2551|M.marinum_M -------AVLAAG-------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 DSEPDHESAPSAGESDSADDDSADDDGPVDLPTGDAGSIDIPDTAESDRG
MLBr_01183|M.leprae_Br4923 ------EIAPPA--------------------------------------
MAV_1346|M.avium_104 ------SIAPAA--------------------------------------
Mb1487c|M.bovis_AF2122/97 GGILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAG-AAGGAGGS
Rv1450c|M.tuberculosis_H37Rv GGILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGAGGAG-AAGGAGGS
MUL_0572|M.ulcerans_Agy99 GGLLWGNGGNGGSGAAGQAGGAGGAAGLIGTGGAGGMGGAGGGAGGMGGS
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mflv_5091|M.gilvum_PYR-GCK GEDAVGYGATGAAGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPG
TH_4332|M.thermoresistible__bu -------DSVGGLGGASHDRSAFSASALG---------------------
MMAR_2551|M.marinum_M ---------------ADEVSAVIAG-----FFGAHAQEYQAISARVATYH
Mvan_4739|M.vanbaalenii_PYR-1 NHGDDTMTAAPSEETADDLSHTQSDPDLSALESVADHEAPPAEPDTAPAT
MLBr_01183|M.leprae_Br4923 ---------------ADDVSILLAH-----FFSGHGRQYQAHASQGATNH
MAV_1346|M.avium_104 ---------------ADEVSALQAA-----QFSAYGTWYQQVSAQAKAIH
Mb1487c|M.bovis_AF2122/97 GG----WLLGNGGVGGAGGQ--SLLGGATGG----------AGGNAGLFG
Rv1450c|M.tuberculosis_H37Rv GG----WLLGNGGVGGAGGQ--SLLGGATGG----------AGGNAGLFG
MUL_0572|M.ulcerans_Agy99 GG----WLLGNGGAGGAGGVGCAGVSGGVGG----------TGGNAMLFG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mflv_5091|M.gilvum_PYR-GCK ---------KAGDAGGAGAVGAAGAAGTVG-----------TAGATGGTG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M QQFVQSLNGSAG------AYAAADAASASS--------------LQTLMR
Mvan_4739|M.vanbaalenii_PYR-1 TRAVQPITAPAEREVIESAYTPTSAAQTTST-----------AVFAPPLT
MLBr_01183|M.leprae_Br4923 QDLIQSLLTSSS------AYAGTETAN-----------------------
MAV_1346|M.avium_104 QTLVQNLDTNAD------SYGATEAANRVN--------------------
Mb1487c|M.bovis_AF2122/97 VGGTGGPGGPG-GPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGG
Rv1450c|M.tuberculosis_H37Rv VGGTGGPGGPG-GPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGG
MUL_0572|M.ulcerans_Agy99 NGGAGGMGGAG-ADGAVGAAGTAG----TSTSAGGVGGAGWDATAAGVLA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------MANIISNGPDG-------
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL
Mflv_5091|M.gilvum_PYR-GCK TGANGGAG----GVGGVG----GTGAAGAAGGAGGLGETGTTG-------
TH_4332|M.thermoresistible__bu --------------------------------MASFGPDWNPGG------
MMAR_2551|M.marinum_M DALNLINAPTNALLG-------------RPLIGNGTNGAPGTGQ------
Mvan_4739|M.vanbaalenii_PYR-1 PAPPSTPVPPVASLAAFASMRRDNEPALRERTTEQSNAAHATVA------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------------------------------TSAA------
Mb1487c|M.bovis_AF2122/97 -HGGVGGAAGLLGVGGHGGAGGHGAAGIAG------------AAGKGGIF
Rv1450c|M.tuberculosis_H37Rv -HGGVGGAAGLLGVGGHGGAGGHGAEGVAG------------AAG-EDLS
MUL_0572|M.ulcerans_Agy99 ATGGDGGDSGGGGAGGNGGAGGAGGHGSA-------------LFGADGAN
MAB_0321c|M.abscessus_ATCC_199 ------------------DAGATGAQGS----------------------
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
Mflv_5091|M.gilvum_PYR-GCK ------------------GAGGVGGQGTAG--------------GTGGVG
TH_4332|M.thermoresistible__bu -----------------AFLGLIGPGGLLIG-------------------
MMAR_2551|M.marinum_M ------------------AGG---PGGILWG-------------------
Mvan_4739|M.vanbaalenii_PYR-1 ------------------AAGGPTPNPVAMA-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------ALQGLAPNVIPNA-------------------
Mb1487c|M.bovis_AF2122/97 PDGSN----------GGAGGDAGDGGTGGRGG-------------WLAGA
Rv1450c|M.tuberculosis_H37Rv PHGTS----------GGVGGDAGDGGTGGRGG-------------WLAGA
MUL_0572|M.ulcerans_Agy99 GNGGA----------GGAGGNPGAPGNGGTGG-------------VGPDA
MAB_0321c|M.abscessus_ATCC_199 ---------------QGATGAAGAMANCN---------------WIDDDC
MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS
Mflv_5091|M.gilvum_PYR-GCK GIGG-----------AGSTGAVGGVGGKG----------------IQGGQ
TH_4332|M.thermoresistible__bu ---------------DGLNGTDAYIDENG-----------------VFHE
MMAR_2551|M.marinum_M ---------------NGGAGGSGAPGQTGGVGG----AAGLFGNGGTGGA
Mvan_4739|M.vanbaalenii_PYR-1 ---------------SPPAGSIMAAVESMLTAARNWFERTFFAATPVYPP
MLBr_01183|M.leprae_Br4923 -------------------------HDSL---------------------
MAV_1346|M.avium_104 ---------------APAADPPPAGTTSLGTSIG----------------
Mb1487c|M.bovis_AF2122/97 GGAGGDGGIGGTGGAGGAGFSRALIVAGDNGGD-----------------
Rv1450c|M.tuberculosis_H37Rv GGAGGAGGVGGTGGAGGAGFSRALIVAGDNGGDPGAGGAGGTGGAGSTIG
MUL_0572|M.ulcerans_Agy99 ATSGGMGGTGGDPGAVGG--------------------------------
MAB_0321c|M.abscessus_ATCC_199 ATRGGTGGTGGNGG------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGG------------AILIG
Mflv_5091|M.gilvum_PYR-GCK GLQGGKGGDGGAGGKG----------------------------------
TH_4332|M.thermoresistible__bu ATRGGNGGLLWGNG------------------------------------
MMAR_2551|M.marinum_M GGTGVTGTPGAAGE------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 QTVMVTVGPGSASDPFTL--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 -----------GGNGGMGG----------AGGAGGPGGAGG--LISLLGG
Rv1450c|M.tuberculosis_H37Rv AHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGG--LVGNGGA
MUL_0572|M.ulcerans_Agy99 ----------RGNSGAAGG----------AGAVAGASGAAGTIIAGNGGN
MAB_0321c|M.abscessus_ATCC_199 -----------------------------PGGAGGPGGHGG--VIDFE--
MSMEG_0868|M.smegmatis_MC2_155 ANGGTVDGHAIGGNGGNGGNGST----TAAGGNGGTGGTGR--VIAEG--
Mflv_5091|M.gilvum_PYR-GCK -----------GDADSMGSAGAT----GGKGGNGGNGGRGG--LFGKGGN
TH_4332|M.thermoresistible__bu -------------------------------GKGGNGLDAGLYTVPDPDN
MMAR_2551|M.marinum_M ----------------SGGTGG-------TGGAGGLGGHGGLLFGNGGTG
Mvan_4739|M.vanbaalenii_PYR-1 ---------------TAADADGRALTYSVHGSTGGTGTAAGTLTISGDKA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 QGAGG-----------------------------------DGGDGGAGGV
Rv1450c|M.tuberculosis_H37Rv GGAGGNGAPGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGAGGAGGK
MUL_0572|M.ulcerans_Agy99 GGAGGAG------------------------------YAADGPAGPAIGN
MAB_0321c|M.abscessus_ATCC_199 VETFMDG-------------------------------------VTLQAK
MSMEG_0868|M.smegmatis_MC2_155 TGSTAEGTATGGDGGHSTGTGIGGNGGIGSV-----YAYGNNGAVSGTAT
Mflv_5091|M.gilvum_PYR-GCK AGNGADG--------------------------------GTGGAGGAGGT
TH_4332|M.thermoresistible__bu PGSTIQMY----------------------------------FEASDGAD
MMAR_2551|M.marinum_M GAGGAGGTGG---------------------------VGGQVNAEGVVGA
Mvan_4739|M.vanbaalenii_PYR-1 TYTPPADWNG---------------------------ETAYTDTFSVTAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 GGDRGAGANGNQAVN-----------------------------------
Rv1450c|M.tuberculosis_H37Rv GGNGGNGATGATGLNGLGA-------------------------------
MUL_0572|M.ulcerans_Agy99 GGDGGHGGAGGFYGN-----------------------------------
MAB_0321c|M.abscessus_ATCC_199 GGRGG---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGR
Mflv_5091|M.gilvum_PYR-GCK GGTGGAGGTGGTGGTGGIG-------------------------------
TH_4332|M.thermoresistible__bu GGRGG---------------------------------------------
MMAR_2551|M.marinum_M GGPGG--TGGVAGAGG----------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 DQRDGFHIHGLSGLIYN---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv -------------------GADGTDGGKGGNGGAGGGGGAGGQGGKALAA
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGAT
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M --------------------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 ------AGAGGAGG-------------------------------HGGDP
Rv1450c|M.tuberculosis_H37Rv THQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNGGSR
MUL_0572|M.ulcerans_Agy99 ------GGAGGAGGN------------------------------SAPGG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGA
Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------------GAG
TH_4332|M.thermoresistible__bu -----------------------------------------------FLF
MMAR_2551|M.marinum_M ------------------------------------------------AA
Mvan_4739|M.vanbaalenii_PYR-1 -----------------------------------------------LTF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 GAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGAGGNGAHFSSGGKAGGNG
Rv1450c|M.tuberculosis_H37Rv GIGGAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANAT---VAGGAG
MUL_0572|M.ulcerans_Agy99 GTGGNGGTGGDSGAMGSSGGRGGDGGVGTNGGAGGGGGNATSYGTANATG
MAB_0321c|M.abscessus_ATCC_199 ----NGGHGG----------------------AGGTGG----------TG
MSMEG_0868|M.smegmatis_MC2_155 AQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATG
Mflv_5091|M.gilvum_PYR-GCK STGGTGGTGG----------------------TGGTGGTGG-------TG
TH_4332|M.thermoresistible__bu GNGGDGGNGGN---------------------VGGKNGADP------VTA
MMAR_2551|M.marinum_M GLFGSPGHAG-----IGGQTGTN------GAAGGGGFG--FREDFINNTG
Mvan_4739|M.vanbaalenii_PYR-1 GLLGRAGHSATTTVTVGVRAASTPPGPDPEPPDGPGVPGSFPVSFANNSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------WAQNVG
Mb1487c|M.bovis_AF2122/97 GAGGAGGHGG--------------LVGNGGAGGAGGNGANGAAGTNASDS
Rv1450c|M.tuberculosis_H37Rv GAGGKGGNGG--------------LVGNGGAGGKGGDGMAGVAGSSPTTA
MUL_0572|M.ulcerans_Agy99 GAGGDGGTG---------------STGNGGSGGDGGNGGTGHGGG----G
MAB_0321c|M.abscessus_ATCC_199 GKGGD---------------------------GDDCEFG-----------
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGG-----------------TGGTGGKGGTGGTGG-----------
TH_4332|M.thermoresistible__bu TVAADKSVAG----------------GNGGNGGRGG--------------
MMAR_2551|M.marinum_M LPDNQIYVTE---------------------IGQTTPGHWAWIDQNGVAH
Mvan_4739|M.vanbaalenii_PYR-1 YADDEVYVMV---------------------IGQVTPGQWSWVDRDGVAH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AAASDFITLG---------------------EGQFAP-------------
Mb1487c|M.bovis_AF2122/97 GAVGGKGNSGGNGGQGGAGGDGGT--LAGNGGAGGTGG------------
Rv1450c|M.tuberculosis_H37Rv GESGTSGQNGGAGGAGGAGGRGGD--FGGDGGTGGAGGNGANGANATTPG
MUL_0572|M.ulcerans_Agy99 GPGGTAINYGAGDAFGGAAGKGGTGVVGGNGGSGGAAYNYG---------
MAB_0321c|M.abscessus_ATCC_199 ----------RTGGNGGTGGRGGDGNFAGTGGNG----------------
MSMEG_0868|M.smegmatis_MC2_155 GAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLG-----------
Mflv_5091|M.gilvum_PYR-GCK --------AGGTGGDGGTGGTGGTGGTGGTGGTGGTG-------------
TH_4332|M.thermoresistible__bu -------LLFGLGGNGGNGGWSTTSYLDARGGNGGNG-------------
MMAR_2551|M.marinum_M PIDHNAADAPGHLTKDGVNYANMSFTLDQAGNLTTPSEFQ----------
Mvan_4739|M.vanbaalenii_PYR-1 HIDHAAADAPGHLEKDGVNYADMTFTLAEADDLRIPPELL----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------VPGAAGIPNFNPGLTAATTAGPPAPAAPAAAA----------
Mb1487c|M.bovis_AF2122/97 -RGADGGLGGSGAEGANATTAGERGQD---------------GGKGGNGG
Rv1450c|M.tuberculosis_H37Rv AKGGDGGHGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGG
MUL_0572|M.ulcerans_Agy99 -TGNATGAGGSSGSGGAASVPNSASTAT------------ATSGSGGAGG
MAB_0321c|M.abscessus_ATCC_199 --------------GAILVKCQHD--------------------------
MSMEG_0868|M.smegmatis_MC2_155 -NGGKGGNGGNGGNGGTYVDPSHTGAGG-------------NGGNGGAGR
Mflv_5091|M.gilvum_PYR-GCK --GAGDGTGGTGGTGGTGGQGGQGGQGG-------------TGGTGGQGG
TH_4332|M.thermoresistible__bu ------GLGGVLRPGGLLSLLLPSGAAS----------------------
MMAR_2551|M.marinum_M -----GGRVFISMKQPLYIAISPDNMG---------------WAGPDPAN
Mvan_4739|M.vanbaalenii_PYR-1 -----GGRIYVSLEQPLYIAISADDSG---------------WASPDGAN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----GAPVLASMGRGPSIGGLSVPPS---------------WAP-----
Mb1487c|M.bovis_AF2122/97 VGGTGGNAVAP-----GANGGHGGNGGNP---------------------
Rv1450c|M.tuberculosis_H37Rv LAGDGGNGANGNFAFGDGNGGHGGNGGNP---------------------
MUL_0572|M.ulcerans_Agy99 DGTDGGNGGSGGFAFTFGTGNIIAGVGGG---------------------
MAB_0321c|M.abscessus_ATCC_199 --LSLGTHPMD------VSAGTGGNGG-----------------------
MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTATGT------ATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
Mflv_5091|M.gilvum_PYR-GCK LGGGGGTGGQG------GTGGTGGQGGTG---------------------
TH_4332|M.thermoresistible__bu --EPGGLFTGG-------NGGNGGLAIAN---------------------
MMAR_2551|M.marinum_M PADPNYSTVYDWYEMTFNNGAIPFGGNTT---------------------
Mvan_4739|M.vanbaalenii_PYR-1 PADPNYETVFDWYEMSYDNGSVPFGGNTT---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------------GGVAPAANAT---------------------
Mb1487c|M.bovis_AF2122/97 ------GFSGAGGLGGLSGDGVTRAAQGATPDFADTGGKGGNGGN-----
Rv1450c|M.tuberculosis_H37Rv ------GAGGQGGSGGAGSTPGAKGAHGFTPTSGGDGGDGGNGGNSQVVG
MUL_0572|M.ulcerans_Agy99 ------GGTGSTGVGGIGGSGGGADINNGAFTVVPQGGAGGHGGDGATDG
MAB_0321c|M.abscessus_ATCC_199 ----------IGGGGGGGGSVGANGAT-----------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
Mflv_5091|M.gilvum_PYR-GCK ---------GTGGTGGTGGTGGAGGDGG----------------------
TH_4332|M.thermoresistible__bu --------HWVGITDGVPGPDDDAVSSS----------------------
MMAR_2551|M.marinum_M ----------QVDQFGFPFSVTVTQDSS----------------------
Mvan_4739|M.vanbaalenii_PYR-1 ----------QVDQFGFPFSFTVSQDAT----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------PAQLVGAGFTSAAPDTAP----------------------
Mb1487c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv GNGGDGGNGGNGGSAGTGGNGGRGGDGAFGGMSANATNPGENGPNGNPGG
MUL_0572|M.ulcerans_Agy99 G-------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVAS-------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M --------------------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 ----------------------------------GANAVAP------GGT
Rv1450c|M.tuberculosis_H37Rv NGGAGGAGGAGLNGGNGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGA
MUL_0572|M.ulcerans_Agy99 ---------------------------------AGGAGGFTEIDSSASVI
MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------T
MSMEG_0868|M.smegmatis_MC2_155 ----------------------------GIGAGGNGGDGIDGGLGGNGGD
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LGGLGGFGGS
TH_4332|M.thermoresistible__bu ------------------------------------------------AY
MMAR_2551|M.marinum_M ------------------------------------------------GF
Mvan_4739|M.vanbaalenii_PYR-1 ------------------------------------------------GF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------VT
Mb1487c|M.bovis_AF2122/97 GASGGAGGNAGAGGKGGENIIGDGGG-----------------GGNG---
Rv1450c|M.tuberculosis_H37Rv GGHGGAGGNGGAGGNGGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGA
MUL_0572|M.ulcerans_Agy99 AATGGAGGDGGSGGTGRGGTGGGGTGG----------------GGTG---
MAB_0321c|M.abscessus_ATCC_199 GVFSSSSDCSGPGPQPNPGSPGDPG-------------------------
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTA-----------SQGGNGGP
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTG-GAGGAGG-------------------------
TH_4332|M.thermoresistible__bu GGHGGHGAGPGSGGNGGSAVANSLGN------------------------
MMAR_2551|M.marinum_M AGTSGLTLSRAQVFQQFATTVPTEFQS-----------------------
Mvan_4739|M.vanbaalenii_PYR-1 SATRGIALSRREVFSAFEDTVPEAYQA-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AVPGGVPSMATAGRGGYGLGAPRYGVK-----------------------
Mb1487c|M.bovis_AF2122/97 -----GAGGQG-GDG----TAGAGG-------------------------
Rv1450c|M.tuberculosis_H37Rv GAFAGGGGGRG-GDGGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGG
MUL_0572|M.ulcerans_Agy99 -----GGGGVGINNGSGEAIGGAPG-------------------------
MAB_0321c|M.abscessus_ATCC_199 ---------------TSVAVSG----------------------------
MSMEG_0868|M.smegmatis_MC2_155 SWVQSGYGSTLGGNATGTATAGKGG-------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------QAGTAGKGG-------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M --------------------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 ----------DGGAGGKGGDGGDGGSDPTEGRG-FGGLGGAG--------
Rv1450c|M.tuberculosis_H37Rv HGGHGAASGGNGGPGGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVL
MUL_0572|M.ulcerans_Agy99 ----------AGGTGAVGGDGGQGGAAYSYGTGDATGSAGAAGTAG----
MAB_0321c|M.abscessus_ATCC_199 ----------------AQGNPGQAQFLIVP--------------------
MSMEG_0868|M.smegmatis_MC2_155 ----------EASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG----
Mflv_5091|M.gilvum_PYR-GCK ----------LFGGSGSAGKAGATGAAGASGGKGAQGATGAQGATG----
TH_4332|M.thermoresistible__bu ---------------AIAGNGGDAGRFVLIGPGGNGGNGGTGLXXX----
MMAR_2551|M.marinum_M --------------LVVHDATGDPVRILSPRTAQPGGLSTWLDPSIN---
Mvan_4739|M.vanbaalenii_PYR-1 --------------LIIRDEDGNPIRILAPRSHQPGSLATWFDEPVD---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------PTVMPKPAI---------------------------
Mb1487c|M.bovis_AF2122/97 ---------------------------GAGGKGGAGTLLG----------
Rv1450c|M.tuberculosis_H37Rv GTNEGDGGDGGRGGNGGRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGAS
MUL_0572|M.ulcerans_Agy99 -------------------------TTGVGGTGGAGGAAYTLNG------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 -------------------------AATTAGATGGAGGFSNIAAIHGAIT
Mflv_5091|M.gilvum_PYR-GCK -------------------------AQGATGATGAAGKAGATGAAGAAGA
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M ---------------------DFWTTYQTNQFNYDGPGYTVQGSVNASDQ
Mvan_4739|M.vanbaalenii_PYR-1 ---------------------DFWHTYRTTEFVYHGTGYTVTGRVGDDDR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 ---LTVFGDNGGAG-----------VLGDSTDPD------GSGGAGGAGG
Rv1450c|M.tuberculosis_H37Rv GDLVTSPGDGGGGGRGGDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGTGG
MUL_0572|M.ulcerans_Agy99 ASTATATGGIGGNG-----------GDGGTANGS-------NGGNGGAGG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 DSTAISGHGGAGNG-----------GNGGKGADG------WVQAYDPAGP
Mflv_5091|M.gilvum_PYR-GCK AGSAGTTGAQGSAG-----------TNGANGANG------SQGAAGKAGA
TH_4332|M.thermoresistible__bu ----------------------------------------PRPRRRRNHR
MMAR_2551|M.marinum_M FVYSVTPTGGSSTT-------------YTMVKPTTAEVFAANGPFVGTAQ
Mvan_4739|M.vanbaalenii_PYR-1 FAYAVTAAGGASTA-------------HSMTKPSTADVFRADGPFVGTGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 AGGAGGDPTI----------------------------------------
Rv1450c|M.tuberculosis_H37Rv TGGQGANGGLTGGRGGTGGNGGNGNTGGTGGAGGTGGTGHNGSQPGMGGN
MUL_0572|M.ulcerans_Agy99 YASTTGTGTASVGNGGRGGDG--TATVATGGTGGVGGN------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 VGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGE
Mflv_5091|M.gilvum_PYR-GCK TG--TTGATGAAGEDGDAGSGGSG-INGGAGGAGG-----------AGGE
TH_4332|M.thermoresistible__bu RTRRRPNGRRPRPPPGR---------------------------------
MMAR_2551|M.marinum_M QGAFLAELDAAFNRGVAISPDQWSNVADYYPTGGRWNNWAEFFHSDSINN
Mvan_4739|M.vanbaalenii_PYR-1 QGAFLAELDAAFNRGVATSPDDWNDVSAYYPAGGRWNDWARFFHAHSLNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv GGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGG
MUL_0572|M.ulcerans_Agy99 --AHAPAGSPVPGVGGKGGNPGPGGKPGPNGADGIVV-------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 HNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK GGEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAG-------GAGGSGGSGG
TH_4332|M.thermoresistible__bu --------------------------------------------------
MMAR_2551|M.marinum_M LAYGFPFDDVNSQSSVLILDNSRPPTELVFNLGG----------------
Mvan_4739|M.vanbaalenii_PYR-1 FAYGFPYDDVNSQSSVVILNNAEPLTDLRLTLTS----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1487c|M.bovis_AF2122/97 ---------------------------------------------
Rv1450c|M.tuberculosis_H37Rv GGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
MUL_0572|M.ulcerans_Agy99 ---------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 ---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGADGTPGTAGTTGANNP--------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGSGGSGGAAGDSDD-----------------------------
TH_4332|M.thermoresistible__bu ---------------------------------------------
MMAR_2551|M.marinum_M ---------------------------------------------
Mvan_4739|M.vanbaalenii_PYR-1 ---------------------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------------
MAV_1346|M.avium_104 ---------------------------------------------