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MSFVGVAPEMVAVAASDLERLGSTISAANVAAAGSTTTILAAGADEVSAVIAALFGTHALEYQAISTQLS VFHEQFVQTLTNGVGAYSAAELVNVLPLQNVEQDLLNLVNAPTQALFGRPLIGNGADGAAGTGQAGAAGG ILWGNGGSGGSGAAGQAGGAGGAAGLIGNGGAGGAGGQGMFNGGSGGAGGWAGLIGAGGAGGVGGTGVAL DGGAGGAGGNAGVLFGPGGIGGSGGQGMASGGAGGAGGASGLVGNGAVGGAGGIGTTDGGAGGQGGNARL FGTGGVGGHGGTGAGSGSGGAGGDGGLGGLVYGNGGGGGAGGVGGAGGAGIVSGAAGSGGHGGTGGAAGL WGVGGHGGDGAHGGAGASGGAGDAGSGGGDAGDGGAGGRGGWLVGGGGAGGSAGSGGGGGAGGSGANAVT LGSAGGNGGNGGDGGAGGVGGAGGRGGWISFLSGQGAGGAGGDGGAGGGAGNGGDGAVGTFFGGTGAGGN GGHGGDPGSGGAGGAGGAGSSAGAAGAGGLSPTTGGNGGNGGRGADGYGTGISGASGGAGGDGGRYGNGG DGGAGGDGMGGASGFSIVFPPGQDGGGGGIGGSGGEGGAGGMGGAMAGHGGDGGAGGHGGQGGSGGSGSR GADGVTGPNPNGGGGGDGGAGGAGGQGGNGGLAGHAQAAGYSDGVQGVGGAGGKGGAGGLAGDGGTGAAG TFASGGNGIGGTGGDGGDNGAGGAGGTGGSGSTTGSDGASGTTTTSGGNGGNGGRGADSVMIGGKGAAGG DGGDGGLYGNGGKGGDGGTGGTGQGGISFLAPGGQTGGDGSTGGTGGTGGAGGSGGAMAGKGGDGGAGGM GGGGGVGGNGSNGDHGVSGGNVNGGTGGDGGKGGSGGQGGNGGAAGKALAASYADGAEGAGGAGGMGGTG GLAGNGGDGADAAAGSAGTGGNGGHGGNNGAGGAGGKGGTGLTTGADGATGSRLTAGGNGGDGGDGGSAA TAGAKGGAGGVGGDGGLYGNGGKGGNGGAGGNGAAGSNASGAGATGGTGLMGGTGGSGGAGGEGGALAGN GGQGGSGGSGGIGGTGGQGGGGSAGGAGVAGVQDGAGGAGGGGGLGGSGGAGGAGGVGGIGGQAHAGGAF HDGDAGAGGLGGKGGTGGTGGKGGTGGGGADATVFEPFAGNGGHGGAGGGGGTGGAGGAGGTSGDGVTVA GAGPTGGTGAGGAGGNGGAGGNADGGGIVNPEYGDGGAGGNGGNGSSGGDGGSGGTGGRSGAGIYNKGGT GGVGGDGGNGTNGAGGKGGSGGNGGRGADASLFADAGDGGTGGDGGDGGTGTTGAGRGGTGGAGGGGGTG TGTPPPFGTGAPGGSGGTGGHGGDSGFGWSGQVGSAGSGPNGVIGGSGGDGGTGGG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2102 | - | - | 100% (1386) | PE-PGRS family protein |
M. marinum M | MMAR_3763 | - | 0.0 | 58.30% (1506) | PE-PGRS family protein |
M. marinum M | MMAR_1442 | - | 0.0 | 58.28% (1503) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 53.53% (1487) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 46.51% (832) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 47.96% (1664) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 4e-11 | 35.87% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-56 | 31.60% (595) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 8e-24 | 44.97% (169) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-174 | 41.00% (1095) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 5e-44 | 38.12% (341) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 48.38% (1176) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-179 | 48.01% (831) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2102|M.marinum_M -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M -----------------------------------------MSFVGVAPE Mb1485c|M.bovis_AF2122/97 -----------------------------------------MSLVIVAPE Rv3508|M.tuberculosis_H37Rv -----------------------------------------MSFVLIAPE MUL_4367|M.ulcerans_Agy99 -----------------------------------------MSFVSVGPG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------MNIVLGVSMAPS MMAR_2102|M.marinum_M MVAVAASDLERLGSTISAANVAAAGSTTTILAAG---------------- Mb1485c|M.bovis_AF2122/97 TVAAAALDVARIGSSIGVANSAAAGSTTSVLAAG---------------- Rv3508|M.tuberculosis_H37Rv FVTAAAGDLTNLGSSISAANASAASATTQVLAAG---------------- MUL_4367|M.ulcerans_Agy99 LLEAAARDLAGLGAGLREANLAAAGATVGVLPAA---------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------MMFLAPPGGPGPISAAIQLTSTG---------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --MSIIDFILNLFRDPVEAASYVADPEAALANAG---------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SIQMVVLEGEYADGATVEEDAIDVTGADDAATAS---------------- MMAR_2102|M.marinum_M ----ADEVSAVIAALFGTHALEYQAISTQLSVFHEQFVQTLTNGVGAYSA Mb1485c|M.bovis_AF2122/97 ----ADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVS Rv3508|M.tuberculosis_H37Rv ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS MUL_4367|M.ulcerans_Agy99 ----GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ Mflv_5091|M.gilvum_PYR-GCK ------------MVTFGGGA------TPTPTSLGAAAVDLSGTSCG---- Mvan_1264|M.vanbaalenii_PYR-1 ----SEATEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG---- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------LSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTG--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------APDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR--- MMAR_2102|M.marinum_M AELVNVLPLQNVEQD---------LLNLVNAPTQALFGRPLIGNGADGAA Mb1485c|M.bovis_AF2122/97 AEATNAAPLATLEHN---------VLNALNAPTQALLGRPLIGDGAAGAP Rv3508|M.tuberculosis_H37Rv AEAA------AAEQI---------VLGVINAPTQALLGRPLIGDGAN-AT MUL_4367|M.ulcerans_Agy99 AEALNMWPLQELEQQ---------ALGVVNAPSMALFGRPSIGNGVDGVA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQD--- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------NPIHDLSGNLQN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------DALAARRIDNVM MMAR_2102|M.marinum_M GTGQAGAAGGILWGNGGSGG-SGAAGQAGGAGGAAGLIGNGGAGGAGGQG Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAGG-- Rv3508|M.tuberculosis_H37Rv TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-- Mflv_5091|M.gilvum_PYR-GCK GTGQN---GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG-- Mvan_1264|M.vanbaalenii_PYR-1 GTGQN---GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG-- MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGW-- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 YYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPS-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSD------- MMAR_2102|M.marinum_M MFNGGSGGAGGWAGLIGAGGAGGVGGTGVALDGGAGGAGGNAG--VLFGP Mb1485c|M.bovis_AF2122/97 -------------------------------AGAAGGAGGSGG--WLLGN Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGWLFGVGGAGGVG------GAGGGTGGAGGPGG--LIWGG MUL_4367|M.ulcerans_Agy99 ---------------VGAAG----------MTGGSGGAGGGGG--WLWGA Mflv_5091|M.gilvum_PYR-GCK ------------------------------LGGGNGGNGGNAGAFALFGN Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------LGSGDGGNGGDAGLFSLFGR MSMEG_0868|M.smegmatis_MC2_155 -------------------------------AGLDGGNGGSGG--LLMGI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------GNVDSFNRGPLLDLSFGD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------GSIPDVYKQQIRAESYGD MMAR_2102|M.marinum_M GGIGGSGGQGMASGGAGG-------------------------------A Mb1485c|M.bovis_AF2122/97 GGVGGAGGQSLLGGATGG-------------------------------A Rv3508|M.tuberculosis_H37Rv GGAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGTDGGPGATGGTGGHGGV MUL_4367|M.ulcerans_Agy99 GGSGGAAGAGG--------------------------------------S Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGVGVVG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGVGIAG------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGAGGAGGVGADG------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LQFGNRDTTAIGDG------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AAGQLSAMVAG--------------------------------------- MMAR_2102|M.marinum_M GGASGLVGNGAVGGAGGIGTTDGGAGGQGGNARLFGTGGVGGHGGTGA-- Mb1485c|M.bovis_AF2122/97 GGNAGLFGVGGTGGPG-------------------GPGGPGGPGGPGG-- Rv3508|M.tuberculosis_H37Rv GGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRG MUL_4367|M.ulcerans_Agy99 GGSGGWLWG--------------------------NAGQTAGAG------ Mflv_5091|M.gilvum_PYR-GCK -----------------------------------ATGAVGAPG------ Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------ATGAVGAPG------ MSMEG_0868|M.smegmatis_MC2_155 --TSAHVDG--------------------------GTGGTGGTGG----- TH_3810|M.thermoresistible__bu ------VD------------------------------GDGGSGG----- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------AVAVGGSNS----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------LEKLESLPGG----- MMAR_2102|M.marinum_M --------GSGSGGAGGDGGLGGLVYGNGGGGGAGGVGGAGGAGIVSGAA Mb1485c|M.bovis_AF2122/97 --------PGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIG--------- Rv3508|M.tuberculosis_H37Rv ALLLGAGGQGGLGGAGGQGGTG----GAGGDGVLGGVGGTGGKGGVGGVA MUL_4367|M.ulcerans_Agy99 -----------VGGAGGAGGAG----DAGDQGVSG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------VAGATGATGVTSGVVGGNGEDAVG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------VAGATGATGVTSNVTGGNGADAVG--------------- MSMEG_0868|M.smegmatis_MC2_155 ----------GTGGTGGIGGTGGGLFGLLGHSGSTG-------------- TH_3810|M.thermoresistible__bu ----------RTG-----------LFSKLSR------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M GSGGHGG-------TGGAAGLWGVGGHGGDGAHGGAGASGGAG------- Mb1485c|M.bovis_AF2122/97 GVGGHGG-------VGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPD Rv3508|M.tuberculosis_H37Rv GLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLT MUL_4367|M.ulcerans_Agy99 --------------------------------------------VAPGEA Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------A TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M -DAGSGGGDAGDGGAGGR--GGWLVGGGGAGGSAGSGGGGGAGGSGAN-- Mb1485c|M.bovis_AF2122/97 GSNGGAGGDAGDGGTGGR--GGWLAGAGGAGGDGGIGGTGGAGGAGFSRA Rv3508|M.tuberculosis_H37Rv GGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADNA MUL_4367|M.ulcerans_Agy99 GAVGFAGGAGGAGGAGGNGVGGGVNGAGGAGGAGGVGGGGGAGASGVG-- Mflv_5091|M.gilvum_PYR-GCK --YGATGAAGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGKA-- Mvan_1264|M.vanbaalenii_PYR-1 --YGATGAAGAAGAAGAAGKAGAVGSAGTAGSAGAPGVWGNAGLPGAA-- MSMEG_0868|M.smegmatis_MC2_155 AGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAA-- TH_3810|M.thermoresistible__bu ------GGDGGDGGLG---------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---GPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTN-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --LLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP- MMAR_2102|M.marinum_M --AVTLGSAGGNGGNGGDGGAGGVGGAGGRGGWISFLSGQGAGGAGGDGG Mb1485c|M.bovis_AF2122/97 --LIVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGG Rv3508|M.tuberculosis_H37Rv SGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQGG MUL_4367|M.ulcerans_Agy99 --AGVAGGDGGTGGAGGAAGVGGAAGTGGTG------GAAGVAGTGGDGG Mflv_5091|M.gilvum_PYR-GCK ------GDAGGAGAVGAAGAAGTVGTAGATG-------GTGTGANGGAGG Mvan_1264|M.vanbaalenii_PYR-1 ------GAAGGAGAIGTAGVAGAAGTAGATG-------GTGVGGNGGAGQ MSMEG_0868|M.smegmatis_MC2_155 ------GPGKGGGGGGGGGGAILIGANGGTV------DGHAIGGNGGNGG TH_3810|M.thermoresistible__bu ----------GNGGHGGGTGIISLLS---------------LAGNGGNGG MAB_4284c|M.abscessus_ATCC_199 --------VSGHGSADIDKSVTVVDDHSQRN-------TTNINDSFNTDR MLBr_01183|M.leprae_Br4923 -----MPLFLNAEPQALTAAANTLEGLSAAT----------VASNAAAAQ MAV_4827|M.avium_104 ----LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSA MMAR_2102|M.marinum_M AGGGAGNGGDGAVGTFFGG--------TGAGGNGGHGGDPGSGGAGGAGG Mb1485c|M.bovis_AF2122/97 AGGVGGDRGAGANGNQAVN--------AGAGGAGGHGGDPGAGGAGGTGG Rv3508|M.tuberculosis_H37Rv AGGAGSAGTDATATGATGGT----GFSGGAGGAGGAGGNTGVGGTNGSGG MUL_4367|M.ulcerans_Agy99 DGGAGGAGSDASLAGQAG-------FAGGSGGAGGVGGSAGAGGVNGSGG Mflv_5091|M.gilvum_PYR-GCK VGGVGGTGAAGAAG--------------GAGGLGETGTTGGAGGVGGQGT Mvan_1264|M.vanbaalenii_PYR-1 AGGIGGTGAAGAAG--------------QAGTAGETGVTGGVGGIGGQGT MSMEG_0868|M.smegmatis_MC2_155 NGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGG TH_3810|M.thermoresistible__bu NGYRTTDNN---------------------ALDGGHGGN------GGNVG MAB_4284c|M.abscessus_ATCC_199 STNIGSGNTTNTEIGSHN-----------QANIGTSTSAGGSAAVGGNAG MLBr_01183|M.leprae_Br4923 LTTEIAPPAADDVSILL------------AHFFSGHGRQYQAHASQGATN MAV_4827|M.avium_104 VGEEDAESPTVVIEKLFLP----------EDSEPRRRPVLLVGSGLAVVG . MMAR_2102|M.marinum_M AGSSAGAAGAGGLSPT-------TGGNGGNGGRGADGYGTGISGASG--- Mb1485c|M.bovis_AF2122/97 AGSTIGAHGAAGASPT-------SGGNGGAGGNGAHFSSGGKAGGNG--- Rv3508|M.tuberculosis_H37Rv QGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGG MUL_4367|M.ulcerans_Agy99 DGGAGAAGGAGGASAT-------VAGSGGVGGDGGAGGAAG--------- Mflv_5091|M.gilvum_PYR-GCK AGGTGGVGGIGGAGST--------GAVGGVGGKGIQG------------- Mvan_1264|M.vanbaalenii_PYR-1 EGGTGGVGGVGGVGAT--------GGAGGVGGKGIQG------------- MSMEG_0868|M.smegmatis_MC2_155 IGSVYAYGNNGAVSGT---------ATGGRGGDGIDGG------------ TH_3810|M.thermoresistible__bu FFSLFNLG-----------------GAGGWGGSGVDG------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGN-------AGLAGNAGLAG---------------- MLBr_01183|M.leprae_Br4923 HQDLIQSLLTSSSAYA---------GTETANHDSL--------------- MAV_4827|M.avium_104 ISAVLALEIALAIGIR---------TTGTVALQPTPN------------- MMAR_2102|M.marinum_M -------------------------------------------------- Mb1485c|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv TNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M -----------GAGGDGGRYGNGGDGGAGGDGMGGASGFSIVFPPGQDGG Mb1485c|M.bovis_AF2122/97 -----------GAGGAGGLVGNGGAGGAGGNGAPGAP------PSGGDPN Rv3508|M.tuberculosis_H37Rv AIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGF MUL_4367|M.ulcerans_Agy99 -----------GGVGAASLGGDGGHAGAGGAGGEGLSGGFNTGAAGGIGG Mflv_5091|M.gilvum_PYR-GCK --------------------GQGLQGGKGGDG------------------ Mvan_1264|M.vanbaalenii_PYR-1 --------------------GQGLQGGQGGDG------------------ MSMEG_0868|M.smegmatis_MC2_155 ---------------------TGGAGGMGEIYS----------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M GGGIGGSGGEGGAGGMGGAMAGHGGDGGAGGHGGQGGSGGSGSRGADGVT Mb1485c|M.bovis_AF2122/97 GGG-GGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNGATGATGLNGLG Rv3508|M.tuberculosis_H37Rv AGGAGGEGGAGGNSGVGGTN-GSGGAGGAGGKGGTGGAGGSGADNPTGAG MUL_4367|M.ulcerans_Agy99 AGGAGGTGGDSG--GVGGVN-GDGGAGGGGGRGGDGGSSTS----TSGVG Mflv_5091|M.gilvum_PYR-GCK --GAGGKGGDADSMGSAGATGGKGGNGGNGGRGGLFGKGGN--------- Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGDATSMGEAGATGGKGGNGGNGGRGSLFGRGGN--------- MSMEG_0868|M.smegmatis_MC2_155 --GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT TH_3810|M.thermoresistible__bu ----------------------VDVVGGN--------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------NAGLAGNAGLAGNAGLAGN--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------QHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVA MMAR_2102|M.marinum_M GPNPNGGGGGDGGAGGAGGQGGNG---------GLAGHAQAAG------- Mb1485c|M.bovis_AF2122/97 -AGADGTDGGKGGNGGAGGGGGAG---------GQGGKALAAT------- Rv3508|M.tuberculosis_H37Rv FAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGD MUL_4367|M.ulcerans_Agy99 GAGGAGGNGGNAGFGVSAGGTG-----------GSAGDGGAGG------- Mflv_5091|M.gilvum_PYR-GCK --AGNGADGGTGGAGGAG------------------GTG----------- Mvan_1264|M.vanbaalenii_PYR-1 --AGNGGNGGTGGNGGNG------------------GTG----------- MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVM----------AAGATGVAT------- TH_3810|M.thermoresistible__bu ---------PDGGTPG---------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----AGLAGNAGLAGNAG------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 APLPAAPPPAAPPLPEAPP------------------------------- MMAR_2102|M.marinum_M --------------------------YSDGVQGVGGAGGKGGAGGLAGDG Mb1485c|M.bovis_AF2122/97 --------------------------HQDGSMGAGGAGGNGGAGGMGGDG Rv3508|M.tuberculosis_H37Rv GASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGATG MUL_4367|M.ulcerans_Agy99 --------------------------GAGGVDGVGGASGNGGAAGAGGAG Mflv_5091|M.gilvum_PYR-GCK --------------------------------GTGGAGGTGGTGGTGGIG Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------GTGGNGGTGGTGGTGGIG MSMEG_0868|M.smegmatis_MC2_155 -----------------------------GNTAIGGNGGAASANGAVGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------LAGNAGLAGNAGLAGNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M GTGAAGTFASGGNG-IGGTGGDGGDNGAG-----GAGGTGGSGSTTGSDG Mb1485c|M.bovis_AF2122/97 GNGAKGTFDNGGDG-VGGNGGNGGSRGIG-----GAGGIGGAGSTAGADG Rv3508|M.tuberculosis_H37Rv AAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGG MUL_4367|M.ulcerans_Agy99 GSGIG----AGIDGGAGGAGGTGGAAGF-----PGGGGTTGAWGTGGAGG Mflv_5091|M.gilvum_PYR-GCK G--------------AGSTGGTGGTGGTG-----GTGGTGGTGGTGGTG- Mvan_1264|M.vanbaalenii_PYR-1 G--------------AGSTGGTGGTGGTG-----GTGGTGGTGGTGGTG- MSMEG_0868|M.smegmatis_MC2_155 GGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGT TH_3810|M.thermoresistible__bu --------AHG----------------------------ESHTP----GV MAB_4284c|M.abscessus_ATCC_199 G-------------------------------------LAGNAGLAGNAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------IPAAPPVVPVPV MMAR_2102|M.marinum_M ASGTTT-------------------------------------------- Mb1485c|M.bovis_AF2122/97 ARGATP-------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGG MUL_4367|M.ulcerans_Agy99 AGGAG--------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --GTGG-------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 --GTGG-------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TIDKGK-------------------------------------------- TH_3810|M.thermoresistible__bu YTDRQ--------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAG-------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VVPPVP-------------------------------------------- MMAR_2102|M.marinum_M -------TSGGNGGNGGRGADSVMIGG----------------------- Mb1485c|M.bovis_AF2122/97 -------TSGGNGGTGGNGANATVAGG----------------------- Rv3508|M.tuberculosis_H37Rv AGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGGDGG MUL_4367|M.ulcerans_Agy99 -------GAGDHGGVGVNPGDSGTAG------------------------ Mflv_5091|M.gilvum_PYR-GCK --------TGGKGGTGGTGGA----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 --------TGGKGGTGGTGGD----------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------AAGGNGGDGGFNGTG---------------------------- TH_3810|M.thermoresistible__bu -------------GEDGEDGTG---------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAG--------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------VPVPVRIPVPDPVSPPQLLAP----------------------- MMAR_2102|M.marinum_M -------------KGAAGGDGGDGGLYGNGGKGGDGGTGGTGQGGISFLA Mb1485c|M.bovis_AF2122/97 -------------AGGAGGKGGNGGLVGNGGAGGKGGDGMAGVAGSSPTT Rv3508|M.tuberculosis_H37Rv DGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGAT MUL_4367|M.ulcerans_Agy99 ------------WAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGA Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGDGGTGGTGGTGGTGGTGGTGGTGGAGDG--- Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGTGGTGGTGGTGGTGGTGGTGGTGGAGDG--- MSMEG_0868|M.smegmatis_MC2_155 --------------GATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRG TH_3810|M.thermoresistible__bu --------------TGIGGRGGNGG-----SSSGTHPMAE---------- MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGN--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------PRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPP--- MMAR_2102|M.marinum_M PGGQTGGDGSTGGTGGTGGAGGSGG-------AMAGKGGDGGAGGMGGGG Mb1485c|M.bovis_AF2122/97 AG-ESGTSGQNGGAGGAGGAGGRGG-------DFGGDGGTGGAGGNGADG Rv3508|M.tuberculosis_H37Rv GAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAG MUL_4367|M.ulcerans_Agy99 GASGIG-AGVAGGDGGTGGTGG-----------AAGTGGAAGTGGTGGAA Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGTGGTGGQGG--------QGGQGGTGGTGGQGGLG Mvan_1264|M.vanbaalenii_PYR-1 ----------LGGTGGTGGTGGFGG--------QGGQGGTGGTGGQGGLG MSMEG_0868|M.smegmatis_MC2_155 GDGGTFVNAGANGNGGAGGAGGVSEGEG----GTGGHGGDGGRGGDGALG TH_3810|M.thermoresistible__bu -------------------------------------DGEHVKALDGRPG MAB_4284c|M.abscessus_ATCC_199 ----------------------------------AAVGGVLNTGVSGAIG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------QHQTPPGEGTPPKPD MMAR_2102|M.marinum_M GVGGNGSN------------------GDHGVSGGNVNGGTGGDGGKGGSG Mb1485c|M.bovis_AF2122/97 GAGGNGAN------------------GANATTPG-AKGGDGGHGGPGAQG Rv3508|M.tuberculosis_H37Rv GAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKG MUL_4367|M.ulcerans_Agy99 GAAGS-----------------------------------AGDGGAGGAG Mflv_5091|M.gilvum_PYR-GCK GGGGT-----------------------------------GGQGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 GVGGT-----------------------------------GGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 GNGGTGGV-------------------------------GLGNGGKGGNG TH_3810|M.thermoresistible__bu LDG--------------------------------------GNGSHGGNG MAB_4284c|M.abscessus_ATCC_199 GSSHVGG---------------------------------AINESLGGSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GPGNYG----------------------------------GGHVPTPGAG MMAR_2102|M.marinum_M GQGGNGGAAGKALAASYAD-GAEGAGGAGGMGGTGGLAGNGGD------- Mb1485c|M.bovis_AF2122/97 GNGGQGGPGGLAGNLFGQN-GIQGVGGSGGKGGAGGLAGDGGN------- Rv3508|M.tuberculosis_H37Rv GAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGGDG MUL_4367|M.ulcerans_Agy99 GAGDDGSAGVVS--------GDPG---------TAGKAGGAG-------- Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTG----------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GQGGTGGTG----------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGTYVDP-------------------------------------- TH_3810|M.thermoresistible__bu GHGGRGG------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGG---------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GSGGSGGGHVP--------------------------------------- MMAR_2102|M.marinum_M ------------GAD-AAAGSAGTGGNGGHG------------GNNGAGG Mb1485c|M.bovis_AF2122/97 ------------GANGNFAFGDGNGGHGGNG------------GNPGAGG Rv3508|M.tuberculosis_H37Rv GEGASGLGLGLSGFDGGQGGQGGAGGSAGAG------------GINGAGG MUL_4367|M.ulcerans_Agy99 -------------------GAGGVGGNGVAG------------GVNGSGG Mflv_5091|M.gilvum_PYR-GCK -------------------GTGGTGGTGGAG------------GDGGLGG Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGAG------------GDGGLGG MSMEG_0868|M.smegmatis_MC2_155 ----------------SHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGG TH_3810|M.thermoresistible__bu -----------------FLGIGGSGGWG------------------GHGG MAB_4284c|M.abscessus_ATCC_199 ------------------GAHTGVGGGVSTG--------------VGVGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------TPGAGGSGGSG--------------GGHVP MMAR_2102|M.marinum_M AGGKGGTGLTTG-------------------------------------- Mb1485c|M.bovis_AF2122/97 QGGSGGAGSTPG-------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDG MUL_4367|M.ulcerans_Agy99 AGGAG--------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK LGGFG--------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 LGGFG--------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGNGD-------------------------------------------- TH_3810|M.thermoresistible__bu NGGDTD-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 HVGGG--------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TPGTG--------------------------------------------- MMAR_2102|M.marinum_M ----------ADGATGSRLTAGGNGGDGGDGGS----------------- Mb1485c|M.bovis_AF2122/97 ----------AKGAHGFTPTSGGDGGDGGNGGH----------------- Rv3508|M.tuberculosis_H37Rv GNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGG MUL_4367|M.ulcerans_Agy99 -------------------GAGGTGGAGASGVP----------------- Mflv_5091|M.gilvum_PYR-GCK -------------------GSGGTGGQGGLGGP----------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------GVGGTGGQGGQGGP----------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------ADGHRGGKGGDGGEALIRA------------ TH_3810|M.thermoresistible__bu -------------------ADGGNGGDGGNGG------------------ MAB_4284c|M.abscessus_ATCC_199 -------------------ISESLGGSGSVGGS----------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------GPGGTGGSGGGHVP----------------- MMAR_2102|M.marinum_M ------------AATAGAKGGAGGVGGDGG-----LYGNGGKGGNGGAGG Mb1485c|M.bovis_AF2122/97 ------------SQVVGGNGGDGGNGGNGG-----SAGTGGNGGRGGDGA Rv3508|M.tuberculosis_H37Rv KGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAG MUL_4367|M.ulcerans_Agy99 ------------ASVDGGDGGAGGAGG-----------AAGTGGSG---- Mflv_5091|M.gilvum_PYR-GCK ---------------GGSTGGAGGAGG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGSTGGAGGAGG----------------------- MSMEG_0868|M.smegmatis_MC2_155 ----TVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQA TH_3810|M.thermoresistible__bu ---------------SAGRGGTGGLRGVF--------------------- MAB_4284c|M.abscessus_ATCC_199 --------------TAVGGGAHTGVGGGVS-------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------TPGAGTPGGSGGGHLP------------------- MMAR_2102|M.marinum_M NGAAGSNASGAGATGGTGLMGGTGGSGGAGGEGGALAGNG---------- Mb1485c|M.bovis_AF2122/97 FGGMSANATNPGENGPNGNPGGNGGAGGAGG-AGLNGGNG---------- Rv3508|M.tuberculosis_H37Rv VGGLANTGGTAGNAGIGG-AGGRGGDGGAGDSGALSQDGNGFAGGQGGQG MUL_4367|M.ulcerans_Agy99 --------GSAGNTGAGG-AGGAGGAGGSAASTGVNGDG----------- Mflv_5091|M.gilvum_PYR-GCK ---------QAGTAGKGGLFGGSGSAGKAGATGAAGASG----------- Mvan_1264|M.vanbaalenii_PYR-1 ---------QAGVAGKGGLFGGSGSAGTAGVTGASGASG----------- MSMEG_0868|M.smegmatis_MC2_155 SGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAG--------- TH_3810|M.thermoresistible__bu -----------GINGGNGR------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------TGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHT--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M ------------GQGGSGGSGGIGGTGGQGGG---------------GSA Mb1485c|M.bovis_AF2122/97 ------------GAGGNGGLGGFGGNGAAGANGVAV-----------GAP Rv3508|M.tuberculosis_H37Rv GVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGV-------------ASE MUL_4367|M.ulcerans_Agy99 ------------GAGGAGGVGGLGGDS--------------------AAT Mflv_5091|M.gilvum_PYR-GCK ------------GKGAQGATGAQGATG---------------------AQ Mvan_1264|M.vanbaalenii_PYR-1 ------------GKGAQGATGAQGATG---------------------AQ MSMEG_0868|M.smegmatis_MC2_155 ---------GNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDG TH_3810|M.thermoresistible__bu -----------------AGLGGRGXX----------------------XX MAB_4284c|M.abscessus_ATCC_199 --------------GVGGGVNTGVGVG------------SHVGGGISESL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------FPGAGSTPGGSG----------------------- MMAR_2102|M.marinum_M GGAGVAGVQDGAGG----AGGGGGLGG----SGGAGGAGGVGG------- Mb1485c|M.bovis_AF2122/97 GQPGGAGGHGGAGG----NGGAGGNGGQGVVSDGAGGAGGAGGDGGAPGD Rv3508|M.tuberculosis_H37Rv GGAGGQGGDGGQGG----IGGAGGNAGFGAGVPGDGGIGGTGG------- MUL_4367|M.ulcerans_Agy99 AGGGGAGGDGGKGG----AGGAGVNGVGG----GDGGKGGTGG------- Mflv_5091|M.gilvum_PYR-GCK GATGATGAAGKAGA----TGAAG-----------AAGAAGSAG------- Mvan_1264|M.vanbaalenii_PYR-1 GATGATGASGAQGS----AGSAG-----------SAGVAGSAG------- MSMEG_0868|M.smegmatis_MC2_155 GKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN------ TH_3810|M.thermoresistible__bu GGGVGAAVRSGNG----VFSGGG--------GTPSAGFGVPTT------- MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGG------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGHLPTPGAGTPGG------------------------------------ MMAR_2102|M.marinum_M --IGGQAHAGGAFHDGDAGAGGLGGKGGTGGTGGKGGTG---GGGADATV Mb1485c|M.bovis_AF2122/97 GANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGGTGSTAGKAGPAGS Rv3508|M.tuberculosis_H37Rv -AGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGN MUL_4367|M.ulcerans_Agy99 -AGGAGGAGSDGIIPSNGGLGGNGGNGGNGGQ-----------AFGDG-- Mflv_5091|M.gilvum_PYR-GCK -TTGAQGSAGTNGANGANGSQGAAGKAGATGT------------------ Mvan_1264|M.vanbaalenii_PYR-1 -TTGAQGSAGTNGANGANGSQGAAGKAGATGT------------------ MSMEG_0868|M.smegmatis_MC2_155 --GGVAGNGGNALVMAAGTTGVATGNTATGGD------------------ TH_3810|M.thermoresistible__bu ----IQFPAGSCTSRAVSREGIMPSSRAASAR------------------ MAB_4284c|M.abscessus_ATCC_199 ------GAHTSAINDALGGSGSVGGSTAVGGG------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---GLGGFGGGHAPAPGGGLGGGGGHAPAPGGG----------------- MMAR_2102|M.marinum_M FEPFAGNGGHGG----AGGGGGTGGAGGAGGTSGDGVT-----VAGAGPT Mb1485c|M.bovis_AF2122/97 ILHDGGNGGHGGHGAASGGNGGPGGHGGNGGNGGTGANGGNGGIGGTGGA Rv3508|M.tuberculosis_H37Rv GGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGA MUL_4367|M.ulcerans_Agy99 ----------------VGGAGGIGGKGGNAAIGTIVING----------- Mflv_5091|M.gilvum_PYR-GCK -----------------TGATGAAGEDGDAGSGGSGING----------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGATGAAGDAGDPGSEAVDING----------- MSMEG_0868|M.smegmatis_MC2_155 ----------------GGAATTAGATGGAGGFSNIAAIHG---------- TH_3810|M.thermoresistible__bu ----------------AGAACASSTSRSRRSFCCSRA------------- MAB_4284c|M.abscessus_ATCC_199 ------------------AHTSAINESMNSSINASHSSS----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------LGGFGGGHSGGGLGGLGGGHK------------- MMAR_2102|M.marinum_M GGTGAG------------GAGGNGGAGGN----ADGGG-IVNPEYGDGGA Mb1485c|M.bovis_AF2122/97 GSTGAKGVLG-----TNEGDGGDGGRGGNGGRGGNGGQ-GLTGAGGNGGT Rv3508|M.tuberculosis_H37Rv GGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGT MUL_4367|M.ulcerans_Agy99 ---------------------------------------GVGGAGGSGGL Mflv_5091|M.gilvum_PYR-GCK ------------------------------------------GAGGAGGA Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------GAGGAGGA MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------AITDSTAISGHGGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MNESFG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M G------GNGGNGSSG------GDGGSGGTGGRSG--------------- Mb1485c|M.bovis_AF2122/97 GGTPGNGGNGGNGASGDLVTSPGDGGGGGRGGDAGRGGDAGLGGSSGPGG Rv3508|M.tuberculosis_H37Rv G------GAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAG MUL_4367|M.ulcerans_Agy99 G------GATEDG------------------------------------- Mflv_5091|M.gilvum_PYR-GCK G------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 G------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 G------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M -AGIYNKGGTGGVGGDGGNGTNG--------AGGKGGSGGNGGRGADASL Mb1485c|M.bovis_AF2122/97 TPGDWGTGGTGGTGGTGGQGANGGL------TGGRGGTGGNGGAGGTGGT Rv3508|M.tuberculosis_H37Rv VPGDGGIGGTGGAGGAGGAGADGDPSID-GGQGGAGGHGGQGGKGGLNST MUL_4367|M.ulcerans_Agy99 ------VGGVGCAGGAG----------------------GNGGRGDMLFT Mflv_5091|M.gilvum_PYR-GCK --------GEGGEGGDG----------------------GKGGAG----- Mvan_1264|M.vanbaalenii_PYR-1 --------GEGGEGGAG----------------------GAGGDG----- MSMEG_0868|M.smegmatis_MC2_155 ------NGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M F---------ADAGDGGTGGDGGDG--GTG-TTG-AGRGGTGGAGGGGGT Mb1485c|M.bovis_AF2122/97 G---------HNGSQPGMGGNGGAG--GFG-GNGFAGVGGRGGMGGSGGT Rv3508|M.tuberculosis_H37Rv GLASAASGDGGNGGAGGAGGNGGAG--GLGGGGGTGGTNGNGGLGGGGGN MUL_4367|M.ulcerans_Agy99 -----------VGGSGGTGGDGGGG--GSASGSGTGGSGGTGGVGGIGGD Mflv_5091|M.gilvum_PYR-GCK -------------AEGGAGGGGGAG--GSG----AGGAGGAGGSGGSGGS Mvan_1264|M.vanbaalenii_PYR-1 -------------SEGGAGGSGGAG--GSG----TGGAGGAGGSGGSGGS MSMEG_0868|M.smegmatis_MC2_155 G-----------GASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGD TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M G-TGTPPPFGTGAP-------------------------GGSGGTGGHGG Mb1485c|M.bovis_AF2122/97 GGTGDAGPFGTGT--------------------------GGTGGHGGQGG Rv3508|M.tuberculosis_H37Rv GGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATGVGNGGNGGDGGNGG MUL_4367|M.ulcerans_Agy99 GKLG------------------------------------GFGGDGGDGG Mflv_5091|M.gilvum_PYR-GCK G---------------------------------------GSGGSGGAAG Mvan_1264|M.vanbaalenii_PYR-1 G---------------------------------------GAGGSGGAAG MSMEG_0868|M.smegmatis_MC2_155 GSEPGPGG-------------------------------NGAGGAGGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2102|M.marinum_M DS------GFGWSGQVGSAGSGPNGVIGGSGGDGGTG--GG---- Mb1485c|M.bovis_AF2122/97 GGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV Rv3508|M.tuberculosis_H37Rv DGGNGAPGGFGGGAGAGGLGG--SGAGGGTDGDDGNGGSPGTDGS MUL_4367|M.ulcerans_Agy99 DGGFGVIGGQGGGGGFGGLGG--TGAGG-APSDKGINGEPGNPG- Mflv_5091|M.gilvum_PYR-GCK DSDD----------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 DSD------------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 TGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP------- TH_3810|M.thermoresistible__bu --------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------- MLBr_01183|M.leprae_Br4923 --------------------------------------------- MAV_4827|M.avium_104 ---------------------------------------------