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MSFLLVQPEMVSAATESLTAIRSALGEVSAAVAGPTTAVVAAAGDEVSAAISQVFGAYGQEFQALNAQAA AFQAEFEGLLSGGAAAYVSAEALNSSVFGPPMQELLKVVNAPTQMLLGRSLIADGANATVAGGDGRPGGI LMGKGGDGAPGGPGQPGGNGGAAGLIGTGGAGGKEAPSMPGGLGGRGGLLWGDGGKGGDGGAPVYDAWGY LLAEAGTGGAGGLPGMFGGLPGVAGAWGGEVPTALAAPMALSAAASSPAAVGGAYQTLFDNTWTNLQAIG ATWNADPAPFLSQFIANQQTYANTVFTSLSNSVQDFGAGLVALPAAYQGAFQALMTGNVSGAVEILGKGY LGLVFNGFDYTNVPVVTVQGALGDLLPITTIPGQISQNMTNVLQTVTDTSIMANISLLSPSFTTGFPLTL ALDALGAPIVTGQAALQSATTFIDAVQAGDVAGAFGAIVDAPAVIANGFLNGEGTITLDLPTYLSPISGT ESLTSAIPIGGILTPLQPVDSTIVFRVLPHTPPVTQHITLGGTEFGGLIPGLQSASAQLADAIKLS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2459 | - | - | 100% (556) | PE-PGRS family protein |
M. marinum M | MMAR_2460 | - | 2e-88 | 36.24% (643) | PE-PGRS family protein |
M. marinum M | MMAR_2458 | - | 1e-86 | 35.54% (650) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1679c | PE_PGRS30 | 3e-81 | 42.52% (461) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 2e-18 | 41.10% (146) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1651c | PE_PGRS30 | 3e-81 | 42.52% (461) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 3e-07 | 29.35% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_0321c | - | 5e-12 | 36.84% (152) | hypothetical protein MAB_0321c |
M. avium 104 | MAV_1346 | - | 4e-13 | 28.25% (269) | PE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-22 | 46.34% (123) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4350 | - | 2e-17 | 28.04% (271) | PUTATIVE putative conserved hypothetical protein |
M. ulcerans Agy99 | MUL_1639 | - | 0.0 | 98.74% (556) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_0928 | - | 5e-21 | 42.41% (158) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -----------------MSGTQSAESDDDADDSEGDASADDAEDAEEFVG TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M --------MS-FLLVQPEMVSAATESLTAIRSALGEVSAAVAGPTTAVVA MUL_1639|M.ulcerans_Agy99 --------MS-FLLVQPEMVSAATESLTAIRSALGEVSAAVAGPTTAVVA Mb1679c|M.bovis_AF2122/97 --------MS-FLLVEPDLVTAAAANLAGIRSALSEAAAAASTPTTALAS Rv1651c|M.tuberculosis_H37Rv --------MS-FLLVEPDLVTAAAANLAGIRSALSEAAAAASTPTTALAS MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAP MAV_1346|M.avium_104 --------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAP Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 DSGNGGSDDDAADDSEKDVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQ TH_4350|M.thermoresistible__bu ----MLASIRPYATAGVALVGAGVIAVTPVAPPPADIQVSRQAVALSAIS MMAR_2459|M.marinum_M AAGDEVSAAISQVFGAYGQEFQALNAQAAAFQAEFEGLLSGGAAAYVSAE MUL_1639|M.ulcerans_Agy99 AAGDEVSAAISQVFGAYGQEFQALNAQAAAFQAEFEGLLSGGAAAYVSAE Mb1679c|M.bovis_AF2122/97 AGADEVSAAVSRLFGAYGQQFQALNARAATFHAEFVSLLNGGAAAYTGAE Rv1651c|M.tuberculosis_H37Rv AGADEVSAAVSRLFGAYGQQFQALNARAATFHAEFVSLLNGGAAAYTGAE MLBr_01183|M.leprae_Br4923 PAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTE MAV_1346|M.avium_104 AAADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATE Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 PASTESTEQSADVANDADGNADPIADAGPEAVTAPVALSGASAPAIPDGP TH_4350|M.thermoresistible__bu NPGDPVVAYGELIANTIG-SLQGLGGQFAADPAPVLVKILQNQIANGQLI MMAR_2459|M.marinum_M ALNSSVFGPPMQELLKVVNAPTQMLLGRSLIADGAN-----ATVAGGDGR MUL_1639|M.ulcerans_Agy99 ALNSSVFGPPMQELLKVVNAPTQMLLGRSLIADGAN-----ATAAGGDGR Mb1679c|M.bovis_AF2122/97 AASVS----SMQALLDAVNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGG Rv1651c|M.tuberculosis_H37Rv AASVS----SMQALLDAVNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGG MLBr_01183|M.leprae_Br4923 TAN----------------------------------------------- MAV_1346|M.avium_104 AANRV-----------NTSAAALQGLAPNVIPNAAP-------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 APVEPMGPLINSLWWAVPKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGR TH_4350|M.thermoresistible__bu GSALDEALGFLLQGVEALPGALEEAFALLTQGDLKG-------------- MMAR_2459|M.marinum_M PGGILMGKGGDGAPGGP-GQPGGNGGAAGLIGTGGAGGKE---APSMPGG MUL_1639|M.ulcerans_Agy99 PGGILMGKGGDGAPGGP-GQPGGNGGAAGLIGTGGAGGKG---APSMPGG Mb1679c|M.bovis_AF2122/97 PGGILYGNGGNGGAGGPDGGAGGNGGAAGLIGNGGAGGAGGVGGAGGAGG Rv1651c|M.tuberculosis_H37Rv PGGILYGNGGNG-------GAGGNGGAAGLIGNGGAGGAGGAGGAGGAGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---AAG MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 CGLICDGADGTEQNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLW TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M LGGRGGLLWGDG-------------------------------------- MUL_1639|M.ulcerans_Agy99 LGGRGGLLWGDG-------------------------------------- Mb1679c|M.bovis_AF2122/97 AGGTGGLLYGNGGAGGNGGSAAAAGGAGGNALLFGNGGNGGSGASGGAAG Rv1651c|M.tuberculosis_H37Rv AGGTGGLLYGNGGAGGNGGSAAAAGGAGGNALLFGNGGNGGSGASGGAAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG--- MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 GSGGDGGAGGAGAAGGTGGNAGLLWGNG---------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M --------------------------GKGGDGGAPVYDAWGY-------- MUL_1639|M.ulcerans_Agy99 --------------------------GKGGDGGAPVYDAWGY-------- Mb1679c|M.bovis_AF2122/97 HAGTIFGNGGNAGAGSGLAGADGGLFGNGGDGGSSTSKAGGAGGNALFGN Rv1651c|M.tuberculosis_H37Rv HAGTIFGNGGNAGAGSGLAGADGGLFGNGGDGGSSTSKAGGAGGNALFGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG--- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 --------------------------GHGGAGGAGVNGAVGTSGVNN--- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M ------------------LLAEAGTGGAGGLPGMFG-----GLPGVAGAW MUL_1639|M.ulcerans_Agy99 ------------------LLAEAGTGGAGGLPGIFG-----GLPGVAGAW Mb1679c|M.bovis_AF2122/97 GGDGGSSTVAAGGAGGNTLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLW Rv1651c|M.tuberculosis_H37Rv GGDGGSSTVAAGGAGGNTLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLW MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------GAGSTGAVGG-----------VGGKGIQGG MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA MAB_0321c|M.abscessus_ATCC_199 ------------------------------------------------MA Mvan_0928|M.vanbaalenii_PYR-1 -----------------GRGGDGTAGGSGGAGGNAGLLSGRGGDGGVGGA TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M G------------------------------------------------- MUL_1639|M.ulcerans_Agy99 G------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GSGGAGGDGGAATSLLGVGMNAGAGGAGGNAGLLYGNGGAGGAGGNGGDT Rv1651c|M.tuberculosis_H37Rv GSGGAGGDGGAATSLLGVGMNAGAGGAGGNAGLLYGNGGAGGAGGNGGDT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK QGLQGGKGGDGGAGGKGGDADSMGS------------------------- MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVAT------------------ MAB_0321c|M.abscessus_ATCC_199 NIISNGPDGD---------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 GGKGGAGAHG---------------------------------------- TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M ---------------------------------GEVPTALAAPMALSAAA MUL_1639|M.ulcerans_Agy99 ---------------------------------GEVPTALAAPMALSAAA Mb1679c|M.bovis_AF2122/97 TVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGA Rv1651c|M.tuberculosis_H37Rv TVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGA MLBr_01183|M.leprae_Br4923 ------------------------------------------HDSL---- MAV_1346|M.avium_104 ----------------------------------AADPPPAGTTSLGTSI Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------AGATGGKGGN MSMEG_0868|M.smegmatis_MC2_155 -----------------------------GNTAIGGNGGAASANGAVGGN MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------AGATGAQGSQ Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------SDAVAAEEDGGPGGSGGA TH_4350|M.thermoresistible__bu ----------------------------------AVDAFMMGIIPAALGM MMAR_2459|M.marinum_M SSPAAVG------------------------------------------- MUL_1639|M.ulcerans_Agy99 SSPAAVG------------------------------------------- Mb1679c|M.bovis_AF2122/97 GGAGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNG Rv1651c|M.tuberculosis_H37Rv GGAGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 GWAQNVG------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGNGGRGGLFG---------------KGGNAGNG---------------- MSMEG_0868|M.smegmatis_MC2_155 GGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN----- MAB_0321c|M.abscessus_ATCC_199 G------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 GGNAGAGGVGGR-------------------------------------- TH_4350|M.thermoresistible__bu IVPLVAGSMIITN------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GNGGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGS Rv1651c|M.tuberculosis_H37Rv GNGGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------ADGGTGG MSMEG_0868|M.smegmatis_MC2_155 --------------------------------GPAGTTIDKGKAAGGNGG MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------ATGAAGA Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------GALLFGRGGDGG TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 LFASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIG Rv1651c|M.tuberculosis_H37Rv LFASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGGAGGTGG-TGGAGGTGG-----------------TGGTGGIGGAGSTG MSMEG_0868|M.smegmatis_MC2_155 DGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTF MAB_0321c|M.abscessus_ATCC_199 MANCNWIDDDCATRGGTGG-----------------TGGNGGPGGAG--- Mvan_0928|M.vanbaalenii_PYR-1 DGGSAGTGGAGGFGGTGGAIVVTLPG-----GKLSDSDGAGGAGGVGGAA TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GTGGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDG Rv1651c|M.tuberculosis_H37Rv GTGGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG---- MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGL MAB_0321c|M.abscessus_ATCC_199 ---GPGGHGGVIDFEVETFMDGVT--LQAKGGRGGNGGHGGAGGTG---- Mvan_0928|M.vanbaalenii_PYR-1 GLGGDGGGGGLGGLLGQAGVNGDSGATAAAGNAGGVGGAGGLGGRLPIVD TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------------- MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GTGGTGGAGGAGSGTKAGGTGSDGGHGGNATLIGNGGDGGAGGAGGAGSP Rv1651c|M.tuberculosis_H37Rv GTGGTGGAGGAGSGTKAGGTGSDGGHGGNATLIGNGGDGGAGGAGGAGSP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GDGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGT MSMEG_0868|M.smegmatis_MC2_155 GNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTAT MAB_0321c|M.abscessus_ATCC_199 GTGGKGGDGDDCEFG---------------------------------RT Mvan_0928|M.vanbaalenii_PYR-1 LNNASPAQATLAALIKKLGLPIQAATG-----------------IQLEDV TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M -------------------------------------------GAYQTLF MUL_1639|M.ulcerans_Agy99 -------------------------------------------GAYQTLF Mb1679c|M.bovis_AF2122/97 AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILGPYEDLI Rv1651c|M.tuberculosis_H37Rv AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILGPYEDLI MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGG MAB_0321c|M.abscessus_ATCC_199 GGNGGTGG-------RGGDGN--------------------FAGTGGNGG Mvan_0928|M.vanbaalenii_PYR-1 DGRLVGPLNAYLYNTIIGKAIFDVGNTFSSASLSARVKEIVILSVGGQWG TH_4350|M.thermoresistible__bu -------------------------------------------------- MMAR_2459|M.marinum_M DNTWTNLQAIGATWNADPAPFLSQFIANQQTYANTVFTSLSNSVQDFGAG MUL_1639|M.ulcerans_Agy99 DNTWTNLQAIGATWNADPAPFLSQFIANQQTYANTVFTSLSNSVQDFGAG Mb1679c|M.bovis_AF2122/97 ANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAIG Rv1651c|M.tuberculosis_H37Rv ANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAIG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------AAASDFITLGEGQFAPVPG Mflv_5091|M.gilvum_PYR-GCK -LGGGGGTG-----------------------GQGGTGGTGGQGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 TLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQG MAB_0321c|M.abscessus_ATCC_199 -----------------------------------AILVKCQHDLSLGTH Mvan_0928|M.vanbaalenii_PYR-1 SEYELYAHKLAAQLFGIPADAIAALANGQAPVGLSGNELLAAQFVQELVS TH_4350|M.thermoresistible__bu ----------------------TADNFARAVSAVLDVDAMLPTLLGFAGP MMAR_2459|M.marinum_M LVALPAAYQGAFQALMTGNVSGAVEILGKGYLGLVFNGFDYTNVPVVTVQ MUL_1639|M.ulcerans_Agy99 LVALPAAYQGAFQALMTGNVSGAVEILGKGYLGLVFNGFDYTNVPVVTVQ Mb1679c|M.bovis_AF2122/97 LAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILLL Rv1651c|M.tuberculosis_H37Rv LAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILLL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 AAGIPNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMGRGPSIG------ Mflv_5091|M.gilvum_PYR-GCK GTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGST MSMEG_0868|M.smegmatis_MC2_155 TIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSAT MAB_0321c|M.abscessus_ATCC_199 PMDVSA--------GTGGNGG------IGGGGGGG--------------- Mvan_0928|M.vanbaalenii_PYR-1 TRRVSDALFEAAEAAFGQTGVVDMVNLAGTYLGVSATLNAFKVRGPESFS TH_4350|M.thermoresistible__bu VLSAVDGFVTSGQAVLDGVLAGDPIAVLNAVASTPAVLIDAVLNGSGALL MMAR_2459|M.marinum_M GALGDLLPITTIPGQISQNMTNVLQTVTDTSIMANISLLSPS--FTTGFP MUL_1639|M.ulcerans_Agy99 GALGDLLPMTTIPGQISQNMTNVLQTVTDTSIMANISLLNPS--FTTGFP Mb1679c|M.bovis_AF2122/97 GPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVMTFGLP Rv1651c|M.tuberculosis_H37Rv GPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVMTFGLP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ---GLSVPPSWAPGGVAPAAN----------------------------- Mflv_5091|M.gilvum_PYR-GCK GGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQG MSMEG_0868|M.smegmatis_MC2_155 GTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEA MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 APVLPAAPSPVPASDEYGLGGRLPLIDLDTATPAQLDLAAKIKALAVPTQ TH_4350|M.thermoresistible__bu G--FLPLPGLLTPATAPIGGPIATLLGIRNAIADALQPVEQIAAASAAAP MMAR_2459|M.marinum_M LTLALDALG-------APIVTGQAALQSATTFIDAVQAGDVAGAFG---- MUL_1639|M.ulcerans_Agy99 LTLALDALG-------APIVTGQAALQSATTFIDAVQAGDVAGAFG---- Mb1679c|M.bovis_AF2122/97 LAMTLNAVG-------SPITTAIAFAESTTAFVSAVQAGNLQAAAA---- Rv1651c|M.tuberculosis_H37Rv LAMTLNAVG-------SPITTAIAFAESTTAFVSAVQAGNLQAAAA---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -ATPAQLVG-------AGFTSAAPDTAPVTAVPGGVPSMATAGRGG---- Mflv_5091|M.gilvum_PYR-GCK ATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG---- MSMEG_0868|M.smegmatis_MC2_155 SNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSN MAB_0321c|M.abscessus_ATCC_199 --GSVGANG--------ATTGVFSSSSDCSGP-GPQPNPGSPGDPG---- Mvan_0928|M.vanbaalenii_PYR-1 QATGIELVSP-----DGRLIGPLNGYLYNPVIGQALFEVGNAFASS---- TH_4350|M.thermoresistible__bu MAAKAEVKAEEEVDAVAAVTSVPGENFRTVNLTTELSTAVENPVAG---- MMAR_2459|M.marinum_M --------------AIVDAPAVIANGFLNGEGTITLDLPTYLSPISGTES MUL_1639|M.ulcerans_Agy99 --------------AIVDAPAVIANGFLNGEETITLDLPTYLSPISGTES Mb1679c|M.bovis_AF2122/97 --------------ALVGAPANVANGFLNGEARLPLALPTSAT---GGIP Rv1651c|M.tuberculosis_H37Rv --------------ALVGAPANVANGFLNGEARLPLALPTSAT---GGIP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 --------------YGLGAPRYGVKPTVMPKPAI---------------- Mflv_5091|M.gilvum_PYR-GCK -------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG------ MSMEG_0868|M.smegmatis_MC2_155 IAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANS MAB_0321c|M.abscessus_ATCC_199 ----------------TSVAVSGAQGNPGQAQFLIVP------------- Mvan_0928|M.vanbaalenii_PYR-1 -----------SLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLVGIPEE TH_4350|M.thermoresistible__bu --------EPKKSAAVDGVPTTVATEEATTGATESLDPAAATEGDDGLED MMAR_2459|M.marinum_M LTSAIPIG-----------------------------------------G MUL_1639|M.ulcerans_Agy99 LTSAIPIG-----------------------------------------G Mb1679c|M.bovis_AF2122/97 VTVEVPVG-----------------------------------------G Rv1651c|M.tuberculosis_H37Rv VTVEVPVG-----------------------------------------G MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --AAGEDGDAGSGGSG-INGGAGGAGG-----------------AGGEGG MSMEG_0868|M.smegmatis_MC2_155 SAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGG MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 AIVSLASGHAPVGLSG-----------------------SELVAARFVQE TH_4350|M.thermoresistible__bu DSAKNANG------------------------------------------ MMAR_2459|M.marinum_M ILTPLQPVDSTIVFRVLPHTPPVTQHITLGGTEFGGLIPGLQS-ASAQLA MUL_1639|M.ulcerans_Agy99 ILTPLQPVESTIVFRVLPHTPPVTQHITLGGTEFGGLIPGLQS-ASAQLA Mb1679c|M.bovis_AF2122/97 ILAPLQPFQATAVIPVIG---PVT--VTLEGTPAGGIVPALVNYAPTQLA Rv1651c|M.tuberculosis_H37Rv ILAPLQPFQATAVIPVIG---PVT--VTLEGTPAGGIVPALVNYAPTQLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK EGGDGGKGGAG--AEGGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSG MSMEG_0868|M.smegmatis_MC2_155 NGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTP MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 LVSTYEVSSELYHSAEAAFGQAGLVDLVNLASTYLGASALLNVFEVPVPT TH_4350|M.thermoresistible__bu -GTDLSDGNKATPATTAGDTSADSGSNKAGQSTLRAGVKKATAKASAASS MMAR_2459|M.marinum_M DAIKLS----- MUL_1639|M.ulcerans_Agy99 DAIKLS----- Mb1679c|M.bovis_AF2122/97 QAIAP------ Rv1651c|M.tuberculosis_H37Rv QAIAP------ MLBr_01183|M.leprae_Br4923 ----------- MAV_1346|M.avium_104 ----------- Mflv_5091|M.gilvum_PYR-GCK GSGGAAGDSDD MSMEG_0868|M.smegmatis_MC2_155 GTAGTTGANNP MAB_0321c|M.abscessus_ATCC_199 ----------- Mvan_0928|M.vanbaalenii_PYR-1 AALITTS---- TH_4350|M.thermoresistible__bu TGGSDE-----