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SFLLVEPDLVTAAAANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQALNARAAT FHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGGPGGI LYGNGGNGGAGGNGGAAGLIGNGGAGGAGGAGGAGGAGGAGGTGGLLYGNGGAGGNGGSAAAAGGAGGNA LLFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSGLAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNG GDGGSSTVAAGGAGGNTLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLWGSGGAGGDGGAATSLLGVGMN AGAGGAGGNAGLLYGNGGAGGAGGNGGDTTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLA SATSGAGGAGGAGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNGGNGGAGGAGGA AALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAGGNG GNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDGG TGGTGGAGGAGSGTKAGGTGSDGGHGGNATLIGNGGDGGAGGAGGAGSPAGAPGNGGTGGTGGVLFGQSG SSGPPGAAALAFPSLSSSVPILGPYEDLIANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALT DATRDFAIGLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILLLGPVGDLFPILS IPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVMTFGLPLAMTLNAVGSPITTAIAFAESTTAFVSAVQA GNLQAAAAALVGAPANVANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVIGPV TVTLEGTPAGGIVPALVNYAPTQLAQAIAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1651c | PE_PGRS30 | - | 100% (1011) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 47.61% (859) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3388 | PE_PGRS52 | 0.0 | 51.98% (756) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1679c | PE_PGRS30 | 0.0 | 99.21% (1018) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-127 | 44.89% (695) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-49 | 29.62% (719) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3570 | - | 0.0 | 48.70% (1035) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-21 | 40.80% (174) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-105 | 36.47% (894) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-42 | 43.00% (307) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-173 | 45.30% (861) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-125 | 43.30% (679) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3570|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3570|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3570|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3570|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv ----------------------------------MS-FLLVEPDLVTAAA
Mb1679c|M.bovis_AF2122/97 ----------------------------------MS-FLLVEPDLVTAAA
MMAR_3570|M.marinum_M ----------------------------------MS-YVIVAPEMLEAAA
MLBr_01183|M.leprae_Br4923 ----------------------------------MPLFLNAEPQALTAAA
MUL_1145|M.ulcerans_Agy99 ----------------------------------MS-YVVASPEYVAAAA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------MSIIDFILNLF
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
Rv1651c|M.tuberculosis_H37Rv ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL
Mb1679c|M.bovis_AF2122/97 ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL
MMAR_3570|M.marinum_M SDLANIGSAIGVANAAAALPTTSVLAAAADEVSAAIAAVFGEHGQAYQAF
MLBr_01183|M.leprae_Br4923 NTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAH
MUL_1145|M.ulcerans_Agy99 SDLAGIGSALSTANAAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQAL
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 RDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQ
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
Rv1651c|M.tuberculosis_H37Rv NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR
Mb1679c|M.bovis_AF2122/97 NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR
MMAR_3570|M.marinum_M SAQATAFHADFVEALTTGVGSYAAAEATNAG--QALLGAVNAPAQALLGR
MLBr_01183|M.leprae_Br4923 ASQGATNHQDLIQSLLTSSSAYAGTETANHD---SL--------------
MUL_1145|M.ulcerans_Agy99 SEQASAFHLQFVQAMTAGAGAYAGAEAVNASPLQAALDVLNAPAQALFGR
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 WVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFA
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
Rv1651c|M.tuberculosis_H37Rv PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNGGAGG-----------N
Mb1679c|M.bovis_AF2122/97 PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNGGAGGPDG----GAGGN
MMAR_3570|M.marinum_M PLIGN---GIDGTATNP--NGGDGGLLYGNGGNGYSQTDGG----LAGGK
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 PLIGDGAGGAPGQ------SGGDGGLLYGNGGNGGNGGVG-----QAGGA
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFG-------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------D
Rv1651c|M.tuberculosis_H37Rv GGAAGLIGNGGAGGAGG--AGGAGGAGGAGGTGGLLYGNGGAGGNGGS--
Mb1679c|M.bovis_AF2122/97 GGAAGLIGNGGAGGAGG--VGGAGGAGGAGGTGGLLYGNGGAGGNGGS--
MMAR_3570|M.marinum_M GGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNGGVLYGNGGTGGAGGSGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GGAAGLIGNGGSGGIGG--PGTTGLAGGAGGSGGWLFGNGGTGGRGGIGT
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG----NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG----NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQ--STAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 NRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG----
MAV_4827|M.avium_104 VYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVG-----------
Rv1651c|M.tuberculosis_H37Rv -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
Mb1679c|M.bovis_AF2122/97 -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
MMAR_3570|M.marinum_M TSYGAAG-VGGNAL-LFGNGGTGGSGLGG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 TGIGGIGGTGGDAVGLFGHGGTGGTGGNGPDIFIAGG-------------
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG--------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA
Mb1679c|M.bovis_AF2122/97 LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA
MMAR_3570|M.marinum_M ----------------------GGNGGNAVFGNGGAGG---AGVAGIGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 -------------------AGGSGGTGGLLFGNGGAGGGAPWGGADGGAG
Mflv_5091|M.gilvum_PYR-GCK --------------------TGANGGAGGVGGVGGTGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------VGGNGGAGQAGGIGGTGAAG----------
MSMEG_0868|M.smegmatis_MC2_155 ------------------TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGA
TH_3810|M.thermoresistible__bu --------------------NGGNVGFFSLFNLGG---------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------SNVGVDQSQTRVGGDYTN-----------
MAV_4827|M.avium_104 ----------------------SGVDVAPLKQVLQTTT------------
Rv1651c|M.tuberculosis_H37Rv GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA
Mb1679c|M.bovis_AF2122/97 GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA
MMAR_3570|M.marinum_M GGNTFIGTGGAGGAGGGTILGGGSHAG---GDGGSVGLWGSGGVGGAG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GDARLIGNGGGGGYEGSLGVLSGGTAGPGGDGGNAVGLIGNGGAGGAG--
Mflv_5091|M.gilvum_PYR-GCK ----AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAV
Mvan_1264|M.vanbaalenii_PYR-1 ----AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGA
MSMEG_0868|M.smegmatis_MC2_155 VSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGA
TH_3810|M.thermoresistible__bu -----AGGWGGSGVDG---------------------VDVVGGNP-----
MAB_4284c|M.abscessus_ATCC_199 -----VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTT
MAV_4827|M.avium_104 ----FLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAV
Rv1651c|M.tuberculosis_H37Rv ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD
Mb1679c|M.bovis_AF2122/97 ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD
MMAR_3570|M.marinum_M TTPDADSGYAGGDGGNG------------GNGGLLYGDGGAGGAGGLGSD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --AAGLSGVTGGIGGNG------------GNGAQLFGNGGAGGAGGQS--
Mflv_5091|M.gilvum_PYR-GCK GGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDADS
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDATS
MSMEG_0868|M.smegmatis_MC2_155 DSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALV
TH_3810|M.thermoresistible__bu -------------------------------------DGGTPG-------
MAB_4284c|M.abscessus_ATCC_199 NTEIGSHNQANIGTSTS--------------AGGSAAVGGNAGLAGNAG-
MAV_4827|M.avium_104 DQYSLPDYLYVPVDPEP--------------GDDELAYSAVGEEDAESPT
Rv1651c|M.tuberculosis_H37Rv TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG
Mb1679c|M.bovis_AF2122/97 TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG
MMAR_3570|M.marinum_M YSSLFYNAGNGGNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYG--GHGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 ------QLASGGTGGSGGMAALFGNGGAGGAAGVSLSGAPGTGGNGGSAQ
Mflv_5091|M.gilvum_PYR-GCK MGS------------------AGATGGKGGNGGNGGRGGLFG--------
Mvan_1264|M.vanbaalenii_PYR-1 MGE------------------AGATGGKGGNGGNGGRGSLFG--------
MSMEG_0868|M.smegmatis_MC2_155 MAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSAT
TH_3810|M.thermoresistible__bu -----------------------AHGESHTPGVYTDRQ------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------LAGNAGLAGNAGLAGNAGLAG--------
MAV_4827|M.avium_104 VVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIG------
Rv1651c|M.tuberculosis_H37Rv AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG
Mb1679c|M.bovis_AF2122/97 AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG
MMAR_3570|M.marinum_M NGGNGGTDGLLFGKGGAG------GDGGAGGGTT-SSGTGGSGGTGGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 FMGDGDSGGLGDSGGSAG------AAG--AGGLIGNPLDVVNAPTEALLG
Mflv_5091|M.gilvum_PYR-GCK -------KGGNAGNGAD----------------------GGTGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 -------RGGNAGNGGN----------------------GGTGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155 SGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNG
TH_3810|M.thermoresistible__bu -------------------------------------------GEDGEDG
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------NAGLAGNAGLAG
MAV_4827|M.avium_104 ------------------------------------IRTTGTVALQPTPN
Rv1651c|M.tuberculosis_H37Rv SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL
Mb1679c|M.bovis_AF2122/97 SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL
MMAR_3570|M.marinum_M SSFIGSGGTGGAG-----------GAG----------GTATGSG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 RPLIGDGADGAPG-----------ESGQDGG----LLYGNGGNGGNGLSG
Mflv_5091|M.gilvum_PYR-GCK TGG-TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 TGG-TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGAN
TH_3810|M.thermoresistible__bu TGTGIGGRGGNGG----------------SSSGTHPMAEDG--------E
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN---------------------AGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 QHLIVPTEQAPAP---------------------PPVQASAPQPKISVPE
Rv1651c|M.tuberculosis_H37Rv GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG
Mb1679c|M.bovis_AF2122/97 GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG
MMAR_3570|M.marinum_M -ASGAGGAGGSG----GYNG---FIGAGGTGGAGGDGGGG----NQGAAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 QAGGAGGAAGLI----GNGGNGGIGGPGTTGMSGGAGGAGGWLIGNGGHG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKG
TH_3810|M.thermoresistible__bu HVKALDGRPGLD---GGNGSHGGNGGHGGRGGFLGIGGSG-------GWG
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLA----GNAGLAGNAGLAGNAGLAGNAGLAG----NAGLA
MAV_4827|M.avium_104 PVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP
Rv1651c|M.tuberculosis_H37Rv GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG
Mb1679c|M.bovis_AF2122/97 GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG
MMAR_3570|M.marinum_M GDGGSGGTAAG------------------LFGAGGTGGTGGTGG--TTTA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GIGGLG------------------------IGIGDSGGAGGAGG--AAIG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG----------------------GTGGTGGTGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG----------------------GTGGTGGTGGAG-------
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGTYV-------------DPSHTGAGGNGGNGGAGRIRVNNG
TH_3810|M.thermoresistible__bu GHGGNGGD------------------------TDADGGNGGDG-------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG-------------------LAGNAAVAGNAAVAG------
MAV_4827|M.avium_104 VPVPVRIPVPDP------------------VSPPQLLAPPRLSVPQPVQP
Rv1651c|M.tuberculosis_H37Rv GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG
Mb1679c|M.bovis_AF2122/97 GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG
MMAR_3570|M.marinum_M NGGTGGAAGVGGSGGDASSLIALGGTGGVGGVGGAATGGGATIGADGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 LFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSWG-GAAA
Mflv_5091|M.gilvum_PYR-GCK ----DGTGGTGGTGG----TGGQGGQGGQGG-----------------TG
Mvan_1264|M.vanbaalenii_PYR-1 ----DGLGGTGGTGG----TGGFGGQGGQGG-----------------TG
MSMEG_0868|M.smegmatis_MC2_155 TATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATG
TH_3810|M.thermoresistible__bu --------GNGGSAG---------------------------------RG
MAB_4284c|M.abscessus_ATCC_199 ---NAAVAGNAAVGG----VLNTGVSGAIGG----------------SSH
MAV_4827|M.avium_104 PVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP-------------PKPD
Rv1651c|M.tuberculosis_H37Rv GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP
Mb1679c|M.bovis_AF2122/97 GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP
MMAR_3570|M.marinum_M GNGGNATGLLNFGGSG-----------------------GAGGAGGAGAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GAGGDAG-LIDNGGDG-----------------------DSAGVLRQ---
Mflv_5091|M.gilvum_PYR-GCK GTGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GTGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQ
MSMEG_0868|M.smegmatis_MC2_155 GDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGH
TH_3810|M.thermoresistible__bu GTGGLRGVFGINGGNG------------------------RAGLGGRGXX
MAB_4284c|M.abscessus_ATCC_199 VGGAINESLGGSGSVG-----------------------GSTAVGGGAHT
MAV_4827|M.avium_104 GPGNYGGGHVPTPGAG-------------------------GSGGSGGGH
Rv1651c|M.tuberculosis_H37Rv AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL
Mb1679c|M.bovis_AF2122/97 AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL
MMAR_3570|M.marinum_M TGVQGAGGMGGTP------GGQPGAAAVSALLPGGLASSTAAVGGAYQDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 ---NGIGGHGGAGGSLFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGL
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQ
MSMEG_0868|M.smegmatis_MC2_155 GGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANA
TH_3810|M.thermoresistible__bu XXGGGVGAAVRSG---------------NGVFSGGGGTPSAGFGVPTTIQ
MAB_4284c|M.abscessus_ATCC_199 GVGGGVSTGVGVG-----------SHVGGGISESLGGSGSVGGSTAVGGG
MAV_4827|M.avium_104 VPTPGAGGSGGSG----------------GGHVPTPGTGGPGGTGGSGGG
Rv1651c|M.tuberculosis_H37Rv IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI
Mb1679c|M.bovis_AF2122/97 IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI
MMAR_3570|M.marinum_M FTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFTL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 IYNSFAGDDGSGGTAIGNGGDGGANIVS-----SGFILGAGGGGNGGNAV
Mflv_5091|M.gilvum_PYR-GCK GGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGAS
Mvan_1264|M.vanbaalenii_PYR-1 GGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGAS
MSMEG_0868|M.smegmatis_MC2_155 ANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTAT
TH_3810|M.thermoresistible__bu FPAGSCTSRAVSREG------------------------IMPSSRAASAR
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTGVGVGSHVGGGISESLGG--------SGSVGGSTAVGGG
MAV_4827|M.avium_104 HVPTPGAGTPGGSGG-----------------------GHLPFPGAGSTP
Rv1651c|M.tuberculosis_H37Rv GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL
Mb1679c|M.bovis_AF2122/97 GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL
MMAR_3570|M.marinum_M GLAGLPPTFQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNIKL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GLIGN----------------GGAGGTGADGFSTALGS------------
Mflv_5091|M.gilvum_PYR-GCK GGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAG
MSMEG_0868|M.smegmatis_MC2_155 AGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATG
TH_3810|M.thermoresistible__bu AG---------------------------AACASSTSRSRRSFCCSRA--
MAB_4284c|M.abscessus_ATCC_199 AHTGVG----------------GGVNTGVGVGSHVGGGISESLGGSGSVG
MAV_4827|M.avium_104 GGSG----------------------------------------------
Rv1651c|M.tuberculosis_H37Rv LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG
Mb1679c|M.bovis_AF2122/97 LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG
MMAR_3570|M.marinum_M LGPVGDLLPILRIPGDTAFNVANVIRTPTDTTVSVEFTSYVPPAITGTFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
Mvan_1264|M.vanbaalenii_PYR-1 SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
MSMEG_0868|M.smegmatis_MC2_155 GAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G-------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV
Mb1679c|M.bovis_AF2122/97 LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV
MMAR_3570|M.marinum_M LPVALTLDAAGSAVTTANAVGTSVTALTNAVQAGDWPAAIGALVDAPAVV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------DGGNGGTGAWLLGNGGAGGSGGSTAGVHPAGDGGNSGMSALI
Mflv_5091|M.gilvum_PYR-GCK G--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEG
Mvan_1264|M.vanbaalenii_PYR-1 G--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEG
MSMEG_0868|M.smegmatis_MC2_155 GSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------STAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINES
MAV_4827|M.avium_104 -------------GGHLPTPGAGTPGGGLGGFGG-----------GHAPA
Rv1651c|M.tuberculosis_H37Rv ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI
Mb1679c|M.bovis_AF2122/97 ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI
MMAR_3570|M.marinum_M ANGFLNGQGTMTVPLSVPIVD--SAVINFPVNGILVPPHDYTATVVIAGF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 GNGGAGGSAGVSPTGVFPSNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGT
Mflv_5091|M.gilvum_PYR-GCK GEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1 GEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGS
MSMEG_0868|M.smegmatis_MC2_155 NTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 MNSSINASHSSSMN----------ESFGSSMGSHGAAGTGFEAQGHAQGH
MAV_4827|M.avium_104 PGGGLGGGGG----------------HAPAPGGGLGGFGGGHSGGGLGGL
Rv1651c|M.tuberculosis_H37Rv GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--
Mb1679c|M.bovis_AF2122/97 GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--
MMAR_3570|M.marinum_M S-YDVPIMGTPIGGIVPGLLTYAPQQFANAIGAAG
MLBr_01183|M.leprae_Br4923 -----------------------------------
MUL_1145|M.ulcerans_Agy99 GGSLAGHDGSDGD----------------------
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGAAGDSDD-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGAGGSGGAAGDSD------------------
MSMEG_0868|M.smegmatis_MC2_155 GGADGTPGTAGTTGANNP-----------------
TH_3810|M.thermoresistible__bu -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASETAHTTLPGAEHH--------------------
MAV_4827|M.avium_104 GGGHK------------------------------