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MSFVNVVPNTVAAAAGDLASIRSALSEATAAAAGPTTDVLAAGGDEVSTAISQLFGAHGQEFQVVSAQLR GFHDQLVRLMRAGAAAYASVEATAQQDLSMAEQGLVNAVNAPAQALLGHPIIGTGGSGSQSATTGTSTSG VTSGSVASGSAAGSVSSGATAGTVSTGATTGSVSSGATAGTVSAGATDGAVTSGTTASSSDGTTVSAGGV AATDPGSDGGVAVSDPGSDGGVAVSGSGSGSGVAVGGTDTPGTSAPAPVTPNTFGDVVAAPYQTLISNTV TNLQSLDGAWAANPAPFLHQLIANQMGYAQTAATALQSSVSNLPAALAHLPADIQLGTHSLMAADPGAFL HSLVTNQLGYAQTISTALQSAAHDFGTGAAALPAAYQAAFQDFMAGNVSGAADHVESGLANLFITGFDVT PGSDAVLSITPTGTVGDLLPILGIPGQMAQNFTNLLPAGSVPELVSQNFTNIVNAATNTAVTSTLTLVVD PSSPTGVGVAIDATMGLPLALGVEALGGPVDAIDAFGTSATAFVTAAQSGNVLAATAAVLDAPAVVANGL FNGQSTFPLTIDALGIPTTLNLPMDGILVPAGPYTATIPDLGVTATVNGTPLGGVAPGLLTLLPEQLAEA IGASPVTD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2458 | - | - | 100% (638) | PE-PGRS family protein |
| M. marinum M | MMAR_2460 | - | e-104 | 37.27% (652) | PE-PGRS family protein |
| M. marinum M | MMAR_2459 | - | 4e-81 | 35.12% (652) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1679c | PE_PGRS30 | 5e-67 | 34.39% (538) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-16 | 36.36% (143) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1651c | PE_PGRS30 | 5e-67 | 34.39% (538) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-10 | 32.63% (95) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_3723c | - | 6e-08 | 30.91% (165) | hypothetical protein MAB_3723c |
| M. avium 104 | MAV_1346 | - | 5e-18 | 28.67% (279) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-11 | 32.67% (150) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4350 | - | 6e-12 | 27.24% (301) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1640 | - | 1e-105 | 37.40% (655) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-16 | 29.32% (249) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_2458|M.marinum_M --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_2458|M.marinum_M --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_2458|M.marinum_M -----------------------------------------MS-FVNVVP
MUL_1640|M.ulcerans_Agy99 -----------------------------------------MS-FVIADP
Mb1679c|M.bovis_AF2122/97 -----------------------------------------MS-FLLVEP
Rv1651c|M.tuberculosis_H37Rv -----------------------------------------MS-FLLVEP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MAV_1346|M.avium_104 -----------------------------------------MS-FVTTRP
TH_4350|M.thermoresistible__bu -------------------------------------MLASIRPYATAG-
MAB_3723c|M.abscessus_ATCC_199 -------------------------------------MADGRGWFPGQGG
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_2458|M.marinum_M ----------------------------------------NTVAAAAGDL
MUL_1640|M.ulcerans_Agy99 ----------------------------------------EMVTAAAADL
Mb1679c|M.bovis_AF2122/97 ----------------------------------------DLVTAAAANL
Rv1651c|M.tuberculosis_H37Rv ----------------------------------------DLVTAAAANL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MAV_1346|M.avium_104 ----------------------------------------EALLAVASML
TH_4350|M.thermoresistible__bu ---------------------------------------VALVGAGVIAV
MAB_3723c|M.abscessus_ATCC_199 ----------------------------------------WQENEGPEDL
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MMAR_2458|M.marinum_M AS------------------------------------------------
MUL_1640|M.ulcerans_Agy99 AG------------------------------------------------
Mb1679c|M.bovis_AF2122/97 AG------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv AG------------------------------------------------
MLBr_01183|M.leprae_Br4923 EG------------------------------------------------
MAV_1346|M.avium_104 EG------------------------------------------------
TH_4350|M.thermoresistible__bu TP------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 AA------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MMAR_2458|M.marinum_M ------IRSALSEATAAAAGPTTDVLAAGGDEVSTAISQLFGAHGQEFQV
MUL_1640|M.ulcerans_Agy99 ------IRSTLGAAAEAAAGPTTGVAAAAADEVSAAIAHLFGAYGQEFQA
Mb1679c|M.bovis_AF2122/97 ------IRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQA
Rv1651c|M.tuberculosis_H37Rv ------IRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQA
MLBr_01183|M.leprae_Br4923 ------LSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MAV_1346|M.avium_104 ------LGSSMDAQNAAAAAPTTSIAPAAADEVSALQAAQFSAYGTWYQQ
TH_4350|M.thermoresistible__bu -------VAPPPADIQVSRQAVALSAISNPGDPVVAYGELIANTIGSLQG
MAB_3723c|M.abscessus_ATCC_199 ------LRRTNRMIDAIAADLPVATSDSDEYAVAMMLAAWREDVGREPMP
. .
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MMAR_2458|M.marinum_M VSAQLRGFHDQLVRLMRAGAAAYASVEATAQQDLS------MAEQGLVNA
MUL_1640|M.ulcerans_Agy99 LNGRAAAFHAELVRLLNGGAASYLSAEVVNVEALLG-----QSLNGGAAA
Mb1679c|M.bovis_AF2122/97 LNARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQ----------ALLDA
Rv1651c|M.tuberculosis_H37Rv LNARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQ----------ALLDA
MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETAN--------------------
MAV_1346|M.avium_104 VSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTSA-----AALQGLAPN
TH_4350|M.thermoresistible__bu LGGQFAADPAPVLVKILQNQIANGQLIGSALDEALG---------FLLQG
MAB_3723c|M.abscessus_ATCC_199 AKPTLGQARNALRDRGGRSRMLATTVGSAAAVTLLFG------GFGAAVY
.
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG---------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP---
MMAR_2458|M.marinum_M VNAPAQALLGHPIIGTGGSGSQSATTGTSTSGVTSGSVA-----------
MUL_1640|M.ulcerans_Agy99 AADPLSGLLGS-ILGTSSGGSG------SVGGILGG--------------
Mb1679c|M.bovis_AF2122/97 VNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNGGAGGP
Rv1651c|M.tuberculosis_H37Rv VNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNG-----
MLBr_01183|M.leprae_Br4923 ---------------HDSL-------------------------------
MAV_1346|M.avium_104 VIPNAAPAADPPPAGTTSLGTSIG--------------------------
TH_4350|M.thermoresistible__bu VEALPGALEEAFALLTQG--------------------------------
MAB_3723c|M.abscessus_ATCC_199 QSHPGDALYGLRTSLFGAPPAVR---------------------------
Mflv_5091|M.gilvum_PYR-GCK ---AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG------------
Mvan_1264|M.vanbaalenii_PYR-1 ---AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG------------
MSMEG_0868|M.smegmatis_MC2_155 -NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGT
MMAR_2458|M.marinum_M ------SGSAAGSVSSGATAGTVSTGATTGSVSSGAT-------------
MUL_1640|M.ulcerans_Agy99 ------SGGLLDPILFGGTGG------LLGPLVGGN--------------
Mb1679c|M.bovis_AF2122/97 DGGAGGNGGAAGLIGNGGAGGAGGVGGAGGAGGAGGTGGLLYGNGGAGGN
Rv1651c|M.tuberculosis_H37Rv --GAGGNGGAAGLIGNGGAGGAGGAGGAGGAGGAGGTGGLLYGNGGAGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AVGAAGAAG------TVGTAGATGGTG---------------TGAN
Mvan_1264|M.vanbaalenii_PYR-1 ----AIGTAGVAG------AAGTAGATGGTG---------------VGGN
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
MMAR_2458|M.marinum_M ----------------------------------------------AGTV
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 GGSAAAAGGAGGNALLFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
Rv1651c|M.tuberculosis_H37Rv GGSAAAAGGAGGNALLFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGV
Mvan_1264|M.vanbaalenii_PYR-1 GGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGI
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGM
MMAR_2458|M.marinum_M SAGATDGAVTSGTTASSSDGTTVSAG-----------GVAATDPGSDGGV
MUL_1640|M.ulcerans_Agy99 --GVLTSLVGSGPLGPFFNGVGGEIG-----------VVTSALIGGDGAV
Mb1679c|M.bovis_AF2122/97 LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGGSSTVAAGGAGGN
Rv1651c|M.tuberculosis_H37Rv LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGGSSTVAAGGAGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu -----------------------------------------DLKGAVDAF
MAB_3723c|M.abscessus_ATCC_199 ---------------------------------------TDPVVLSAQTE
Mflv_5091|M.gilvum_PYR-GCK GGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
MMAR_2458|M.marinum_M AVSDPGSDGGVAVSGSGSGSGVAVGGTDTPGTSAPAPV------------
MUL_1640|M.ulcerans_Agy99 LLSD--QIGGITGTLT-SLPGLSGLQTLLPGLFPSSGD------------
Mb1679c|M.bovis_AF2122/97 TLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLWGSGGAGGDGGAATSLLG
Rv1651c|M.tuberculosis_H37Rv TLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLWGSGGAGGDGGAATSLLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu MMGIIPAALGMIVPLVAGSMIITNTADNFAR-------------------
MAB_3723c|M.abscessus_ATCC_199 LAQVEKLISQGDWEEAQQQLGVAAARVNEVG-------------------
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
MMAR_2458|M.marinum_M ------------------------------------------------TP
MUL_1640|M.ulcerans_Agy99 ------------------------------------------------TT
Mb1679c|M.bovis_AF2122/97 VGMNAGAGGAGGNAGLLYGNGGAGGAGGNG---------------GDTTV
Rv1651c|M.tuberculosis_H37Rv VGMNAGAGGAGGNAGLLYGNGGAGGAGGNG---------------GDTTV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
MMAR_2458|M.marinum_M NTFGDVVAAP-----YQTLISN-----------TVTNLQ-----------
MUL_1640|M.ulcerans_Agy99 TTP--APGGA-----WQQLFEN-----------TSSNLN-----------
Mb1679c|M.bovis_AF2122/97 PLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGAGG
Rv1651c|M.tuberculosis_H37Rv PLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
MMAR_2458|M.marinum_M --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 AGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNGGN
Rv1651c|M.tuberculosis_H37Rv AGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
MMAR_2458|M.marinum_M ---------------SLDGAWAANPAPFLH--------------------
MUL_1640|M.ulcerans_Agy99 ---------------ALGTAWSEDPFPLLR--------------------
Mb1679c|M.bovis_AF2122/97 GGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGSLF
Rv1651c|M.tuberculosis_H37Rv GGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGSLF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGG--------------
MMAR_2458|M.marinum_M --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 ASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIGGT
Rv1651c|M.tuberculosis_H37Rv ASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------GTGGTGGTGGAG-----
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------GTGGTGGTGGAG-----
MSMEG_0868|M.smegmatis_MC2_155 -------------------------TYVDPSHTGAGGNGGNGGAGRIRVN
MMAR_2458|M.marinum_M --------------------------------------------------
MUL_1640|M.ulcerans_Agy99 --------------------------------------------------
Mb1679c|M.bovis_AF2122/97 GGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDGGT
Rv1651c|M.tuberculosis_H37Rv GGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------DGTGGTGGTGG----TGGQGGQGGQGG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ------DGLGGTGGTGG----TGGFGGQGGQGG-----------------
MSMEG_0868|M.smegmatis_MC2_155 NGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTA
MMAR_2458|M.marinum_M ----------------------------QLIAN-----------------
MUL_1640|M.ulcerans_Agy99 ----------------------------QVIAN-----------------
Mb1679c|M.bovis_AF2122/97 GGTGGAGGAGSGTKAGGTGSDGGHGGNATLIGNGGDGGAGGAGGAGSPAG
Rv1651c|M.tuberculosis_H37Rv GGTGGAGGAGSGTKAGGTGSDGGHGGNATLIGNGGDGGAGGAGGAGSPAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGQGG-LGGGGGTG-----------------------GQGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGQGG-LGGVGGTG-----------------------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGING
MMAR_2458|M.marinum_M QMGYAQTAAT---------------ALQSSVSNLPAALAHLP--ADIQLG
MUL_1640|M.ulcerans_Agy99 QQGYAYTLGQ---------------DLSLAIQNLPTELAHLP--ENIETG
Mb1679c|M.bovis_AF2122/97 APGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILGPYEDLIAN
Rv1651c|M.tuberculosis_H37Rv APGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILGPYEDLIAN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 GQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQG
MSMEG_0868|M.smegmatis_MC2_155 GHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTA
MMAR_2458|M.marinum_M THSLMA-------ADPGAFLHSLVTNQLGYAQTISTALQSAAHDFGTGAA
MUL_1640|M.ulcerans_Agy99 IQGFLA-------FNPGLYAQQFVASTMNDFHTIGTSLSEAGQDLQIGLA
Mb1679c|M.bovis_AF2122/97 TVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAIGLA
Rv1651c|M.tuberculosis_H37Rv TVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAIGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------WAQNVGAAASDFITLGEGQFAPVPGAA
TH_4350|M.thermoresistible__bu ----------------------AVSAVLDVDAMLPTLLGFAG-PVLSAVD
MAB_3723c|M.abscessus_ATCC_199 ------------------------DAQQKAELASRVQQAEVRIDAKDPQA
Mflv_5091|M.gilvum_PYR-GCK GLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASG
MSMEG_0868|M.smegmatis_MC2_155 NAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGT
MMAR_2458|M.marinum_M ALPAAYQAAFQDFMAGNVSGAADHVESGLANLFITGFDVTPGSDAVLSIT
MUL_1640|M.ulcerans_Agy99 GFPADMQPAYEAFAAGNYNLAVNDATKALLNVFITGFDTSN----LNDIR
Mb1679c|M.bovis_AF2122/97 GIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASD----LSNIL
Rv1651c|M.tuberculosis_H37Rv GIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASD----LSNIL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GIPNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMGRGPSIG--------
TH_4350|M.thermoresistible__bu GFVTSGQAVLDGVLAGDPIAVLNAVASTPAVLIDAVLNGSGALLGFLPLP
MAB_3723c|M.abscessus_ATCC_199 TVPPEMVTETPRIMLSPPSIAPITSTTTTSTTSTTSASTTTSDSTSASTS
Mflv_5091|M.gilvum_PYR-GCK ASGGKGAQGATGAQGATG-------------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 ASGGKGAQGATGAQGATG-------------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 ATAGKGGEASNGGVAGNGGNALV-------MAAGTTGVATGNTATGGDGG
MMAR_2458|M.marinum_M PTGTVGDLLPILGIPGQMAQNFTNLLPAGSVPELVSQNFTNIVNAATNTA
MUL_1640|M.ulcerans_Agy99 LLGPVADLFPILALPGQDVQGFSNLLPAGSIPAQMTHNLANVLNALTDTS
Mb1679c|M.bovis_AF2122/97 LLGPVGDLFPILSIPG-----------------AMSQNFTNVVMTVTDTT
Rv1651c|M.tuberculosis_H37Rv LLGPVGDLFPILSIPG-----------------AMSQNFTNVVMTVTDTT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------------------------GLS
TH_4350|M.thermoresistible__bu GLLTPATAPIGGPIATLLG---------------IRNAIADALQPVEQIA
MAB_3723c|M.abscessus_ATCC_199 TTETSGSASPSTSSSTSTS--------------ATASTSVTSVPTSTPTT
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MMAR_2458|M.marinum_M VTSTLTLVVDPSSPTGVGVAIDATMGLPLALGVEALGGPVDAIDAFGTSA
MUL_1640|M.ulcerans_Agy99 ISTTISGTLDPP-----ALVLDANFGLPLSILFGVAGAPVAGLDGLATAG
Mb1679c|M.bovis_AF2122/97 IAFSIDTTNLTG---------VMTFGLPLAMTLNAVGSPITTAIAFAEST
Rv1651c|M.tuberculosis_H37Rv IAFSIDTTNLTG---------VMTFGLPLAMTLNAVGSPITTAIAFAEST
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 VPPSWAPGGVAP-------AANATPAQLVGAGFTSAAPDTAPVTAVPGGV
TH_4350|M.thermoresistible__bu AASAAAPMAAKA-------EVKAEEEVDAVAAVTSVPGENFRTVNLTTEL
MAB_3723c|M.abscessus_ATCC_199 VTITTTPPSSAATITSTPASATETTTAPSVSTAPTTSVPGVTASTTVPPT
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MMAR_2458|M.marinum_M TAFVTAAQSGNV---LAATAAVLDAPAVVANGLFNGQ----STFPLTIDA
MUL_1640|M.ulcerans_Agy99 TTIGTGVASGNP---FMVVGGLIDAPAVVLDGFLNGETIVDMSLPVTFDV
Mb1679c|M.bovis_AF2122/97 TAFVSAVQAGNL---QAAAAALVGAPANVANGFLNGEARLPLALPTSATG
Rv1651c|M.tuberculosis_H37Rv TAFVSAVQAGNL---QAAAAALVGAPANVANGFLNGEARLPLALPTSATG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PSMATAGRGGYG---LGAPRYGVKPTVMPKPAI-----------------
TH_4350|M.thermoresistible__bu STAVENPVAGEP----KKSAAVDGVPTTVATEEATTGATESLDPAAATEG
MAB_3723c|M.abscessus_ATCC_199 ASIVTVPTTPEG------VTIVTTRPGVVNTPVITAPTTIEAPVPITRTP
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MMAR_2458|M.marinum_M -----LGIPTTLNLPMDGILVPAGPYTATIP------DLGVTATVNGTPL
MUL_1640|M.ulcerans_Agy99 PVLGPLNIPVVIHLPFQGLLVPPHPITATVPLEILGVDIPINLTLGGTQF
Mb1679c|M.bovis_AF2122/97 ------GIPVTVEVPVGGILAPLQPFQATAVIPVIG---PVTVTLEGTPA
Rv1651c|M.tuberculosis_H37Rv ------GIPVTVEVPVGGILAPLQPFQATAVIPVIG---PVTVTLEGTPA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
TH_4350|M.thermoresistible__bu ----DDGLEDDSAKNANGGTDLSDGNKATPATTAGDTSADSGSNKAGQST
MAB_3723c|M.abscessus_ATCC_199 ----DNPAPAYQAPVNSPGSGNLHGYPGSGGNAGSGSDGPSRHMPAMTSV
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
MMAR_2458|M.marinum_M GGVAPGLLTLLPEQLAEAIGASPVTD-
MUL_1640|M.ulcerans_Agy99 GGLVPTLVNYTSRHLANAITPAA----
Mb1679c|M.bovis_AF2122/97 GGIVPALVNYAPTQLAQAIAP------
Rv1651c|M.tuberculosis_H37Rv GGIVPALVNYAPTQLAQAIAP------
MLBr_01183|M.leprae_Br4923 ---------------------------
MAV_1346|M.avium_104 ---------------------------
TH_4350|M.thermoresistible__bu LRAGVKKATAKASAASSTGGSDE----
MAB_3723c|M.abscessus_ATCC_199 PVAPANPGSGSANQGSGSGSHTDE---