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VGVSAHALANLDSPSSLARTALLLAGALLCLSVAAWPVLSQRRRQHPETQEQLFAGTNVPYAAPPQRRQS DGGRLTIAALICAAGFVAAIWLPSKSTMPARPLVALPGASAIAPGTGIAVTYADGSGGMGCTAGFLVRTN AGRTGILTAGHCNKEGEASKVSINYSAGGGYVNIGTFSQSVSEGLNGEAHDIGLITLDSGKIPQSPAIKA AVPVTGIATDLKVGQLLCKFGMKTGRAECGQVTDISASKVAFLAASECGDSGGPVYRLDDDGTAVAVGIL IRAGHANDPHPGCSTPATFSIAELVRPWLDRWSLTAITEPGSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2300 | - | - | 100% (324) | hypothetical protein MMAR_2300 |
| M. marinum M | MMAR_1484 | - | 3e-05 | 25.50% (251) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1845 | - | 7e-08 | 27.91% (215) | hypothetical protein Mb1845 |
| M. gilvum PYR-GCK | Mflv_0488 | - | 2e-19 | 33.20% (241) | hypothetical protein Mflv_0488 |
| M. tuberculosis H37Rv | Rv1815 | - | 3e-07 | 27.44% (215) | hypothetical protein Rv1815 |
| M. leprae Br4923 | MLBr_02242 | - | 3e-09 | 25.59% (211) | hypothetical protein MLBr_02242 |
| M. abscessus ATCC 19977 | MAB_2805c | - | 4e-08 | 27.49% (211) | hypothetical protein MAB_2805c |
| M. avium 104 | MAV_3280 | - | 3e-86 | 51.20% (332) | hypothetical protein MAV_3280 |
| M. smegmatis MC2 155 | MSMEG_6359 | - | 2e-10 | 28.63% (255) | trypsin domain-containing protein |
| M. thermoresistible (build 8) | TH_2227 | - | 3e-07 | 28.87% (194) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1503 | - | 1e-156 | 98.89% (271) | hypothetical protein MUL_1503 |
| M. vanbaalenii PYR-1 | Mvan_3169 | - | 1e-06 | 30.63% (160) | hypothetical protein Mvan_3169 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2300|M.marinum_M MVGVSAHALANLDSPSSLARTALLLAGALLCLSVAAWPVLSQRRRQHPET
MUL_1503|M.ulcerans_Agy99 --------------------------------------------------
MAV_3280|M.avium_104 MVSVDALELASWGTPYSPARTVALPLGALVLAVLAVLGFLPGRAERRRKP
Mflv_0488|M.gilvum_PYR-GCK --------------------------------------------------
Mb1845|M.bovis_AF2122/97 --------------------------------------------------
Rv1815|M.tuberculosis_H37Rv --------------------------------------------------
TH_2227|M.thermoresistible__bu --------------------------------------------------
Mvan_3169|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2805c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6359|M.smegmatis_MC2_155 ------------------------------------------MTGGVYAP
MLBr_02242|M.leprae_Br4923 --------------------------------------------------
MMAR_2300|M.marinum_M QEQLFAGTNVPYAAPPQRRQSDGGRLTIAALICAAGFVAAIWLPSKSTMP
MUL_1503|M.ulcerans_Agy99 ---MFAGTNVPYAAPPQRRQSDGGRLTIAALICAAGFVAAVWLPSKSTMP
MAV_3280|M.avium_104 ATGAFPATDV----LPPRPRTHTTVLTLAAVCSITALVAAVCLLPSAATP
Mflv_0488|M.gilvum_PYR-GCK ---------------MMRNLLKTVGGTAAAALAALTFTQAPVAHAFGEYP
Mb1845|M.bovis_AF2122/97 -----------------------MVRLVPRAFAATVALLAAGFSPATASA
Rv1815|M.tuberculosis_H37Rv -----------------------MVRLVPRAFAATVALLAAGFSPATASA
TH_2227|M.thermoresistible__bu --------------------------------MVLAPLAALTLASAPAHS
Mvan_3169|M.vanbaalenii_PYR-1 ------------------MSGRSSSRVLHLLFAVLAPVLALALQTVPAQA
MAB_2805c|M.abscessus_ATCC_199 ------------------------MSAVAAVAGVLVASPALSIADPAAET
MSMEG_6359|M.smegmatis_MC2_155 VPPGVPAPTPTPVKPRRRILRRLLITSLGLATVLAVAFVAFVFWPNPTVP
MLBr_02242|M.leprae_Br4923 ---------MRSIYWFTGETCATVRWLRGLGLASAAVIAPKVFASMVLAE
.
MMAR_2300|M.marinum_M ARP----------LVALPGASAIAPGTGIAVTYADGSGG-MGCTAGFLVR
MUL_1503|M.ulcerans_Agy99 ARP----------LVALPGASAIAPGTGIAVTYADGSGG-MGCTAGFLVR
MAV_3280|M.avium_104 AQQPTPPPVLA--PIDLPAASAIGPGAGIYVDYTDGSGG-MGCTAGFLVH
Mflv_0488|M.gilvum_PYR-GCK VAS---------------------PGAHLVSTTLAGNGLPYQCTAGFTVR
Mb1845|M.bovis_AF2122/97 DP------------------VLVFPGMEIRQDNHV-------CTLGYVDP
Rv1815|M.tuberculosis_H37Rv DP------------------VLVFPGMEIRQDNHV-------CTLGYVDP
TH_2227|M.thermoresistible__bu SPG-----------------VVVHPGMEIHQDTNS-------CTLGFIDA
Mvan_3169|M.vanbaalenii_PYR-1 QPG-----------------VLVFPGMEIHQDTVL-------CTLGYVDP
MAB_2805c|M.abscessus_ATCC_199 APK-----------------IVAFPGMSIVQGDSR-------CTLGYVDP
MSMEG_6359|M.smegmatis_MC2_155 ADQPNMTQVMTGTDNDWLSFDDFVPGTAIAADGSDNDE--YECTLGFLGR
MLBr_02242|M.leprae_Br4923 YAP--------------------SPGLRLCDESSI-------CTAACVAR
** : ** .
MMAR_2300|M.marinum_M TNAGRTGILTAGHCNKEGEASKVSINYSAGGGYVNIGTFSQSVSEGL---
MUL_1503|M.ulcerans_Agy99 TNAGRTGILTAGHCNKEGEASKVSINYSTGGGYVNIGTFSQSVSEGL---
MAV_3280|M.avium_104 TSSGQAGILTAGHCNRSGEPSKVTMNLGGVLPYATLGTFSQTISEGV---
Mflv_0488|M.gilvum_PYR-GCK TPGGSPGMLTAGHCDRDPLNDTVLQRTPTGDRVVGRYVRWEVLPG-----
Mb1845|M.bovis_AF2122/97 ALKIA---FTAGHCRGGGAVTSRDYKVIGHLRAFRDNTPSGSTVAT----
Rv1815|M.tuberculosis_H37Rv ALKIA---FTAGHCRGGGAVTSRDYKVIGHLRAIRDNTPSGSTVAT----
TH_2227|M.thermoresistible__bu VRRIA---YTAGHCRGSGTVTDRAGRFIGTQLMFRDNTPNGSTVAT----
Mvan_3169|M.vanbaalenii_PYR-1 QTRIG---YTAGHCRASGTVSDKFGTMIGTQGTFRDNTPDGMTVDT----
MAB_2805c|M.abscessus_ATCC_199 VSRIG---LTAGHCNATGSIVDLAGNRLGEVLLMSRNLPTGGAIGP----
MSMEG_6359|M.smegmatis_MC2_155 DSSGTPIGFTAGHCDRPGDDSPHFTRKADEDTPVELGRFTTVQTADMPDK
MLBr_02242|M.leprae_Br4923 GNDGSSYLLTIGHCDAYDG----SVWPYGPDVPLGKRTVSENEGDR----
* ***
MMAR_2300|M.marinum_M -----NGEAHDIGLITLDSGKIP----QSPAIKAAVPVTGIATD--LKVG
MUL_1503|M.ulcerans_Agy99 -----NGEAHDIGLITLDSGKIP----QSPAIKAAVPVTGIATD--LKVG
MAV_3280|M.avium_104 -----HDEQHDIGLITLDGDNVP----QSPAIAASVPVSGVAAN--LQVG
Mflv_0488|M.gilvum_PYR-GCK --------VRDVGLVDLAGSSVP----LVDQVDGMRVSRVMSGDDVRREQ
Mb1845|M.bovis_AF2122/97 -----HELIADYEAIVLADDVTA----SNILPSGRALESRPGVVL--HPG
Rv1815|M.tuberculosis_H37Rv -----HELIADYEAIVLADDVTA----SNILPSGRALESRPGVVL--HPG
TH_2227|M.thermoresistible__bu -----DHQIADWQTIQLAGDVVM----NNVLPTGRVLVEDPTVVP--QPG
Mvan_3169|M.vanbaalenii_PYR-1 -----NHQIIDWEVIHLAPHVAV----NNVLPGGKVLVTDPAVLP--VRG
MAB_2805c|M.abscessus_ATCC_199 -----GDVVSDYEGISFGPGVEL----SSNLPNGLALRMAQNAGP--ELG
MSMEG_6359|M.smegmatis_MC2_155 VVKTGPDGWSDFAVIEIDPSLTDSAEDNARIAGVYRVTKVLDYEYLLNNN
MLBr_02242|M.leprae_Br4923 ---------KDAAIILLDLSQGY----SSGDVYSQLLRNVLSENE-IQLG
* : :
MMAR_2300|M.marinum_M QLLCKFGMKTGRAECGQVTDISA--SKVAFLAASECGDSGGPVYRLDDDG
MUL_1503|M.ulcerans_Agy99 QLLCKFGMKTGRAECGQVTDISA--SKVAFLAASECGDSGGPVYRLDDDG
MAV_3280|M.avium_104 QQLCKFGMGSGADACGQIVEITG--SKVKFLAGGQCGDSGGPVYRYENDG
Mflv_0488|M.gilvum_PYR-GCK PELCKSGARTG-LSCGPVTSVTD--NQVSFRAWDDLGDSGAPVYARQPDG
Mb1845|M.bovis_AF2122/97 QAVCHFGVSTG-ETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGG
Rv1815|M.tuberculosis_H37Rv QAVCHFGVSTG-ETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGG
TH_2227|M.thermoresistible__bu QPVCHFGVVTG-ESCGRIAAVNNGWFTMGDGVVSQKGDSGGPVYTVNEAG
Mvan_3169|M.vanbaalenii_PYR-1 MPVCHFGVVTG-ESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDG
MAB_2805c|M.abscessus_ATCC_199 LPVCLMGSVSG-ETCGKVEAINNGWFTMVD-VAGQHGDSGGPVYTVTQPG
MSMEG_6359|M.smegmatis_MC2_155 VTLCKFGFVSG-ETCGKVIGHDN--LTVEAELYSASGDSGSPAYVKFGND
MLBr_02242|M.leprae_Br4923 MLFCKVGAITG-ETCGTIKSMDG--DVVEASVYSLSAGSGSPGFVKNVDG
.* * :* ** : : . ..**.* : .
MMAR_2300|M.marinum_M TAVAVGILIRAGHANDPHPGCSTPATFSIAELVRPWLDRWSLTAITEPGS
MUL_1503|M.ulcerans_Agy99 TAVAVGILIRAGHANDPHPGCSTPATFSIAELVRPWLDRWSLTAITEPGS
MAV_3280|M.avium_104 TVSAVGILIRGGDPYTRKAGCAARAKFSVAELVRPWLDTWRLTMVTAASA
Mflv_0488|M.gilvum_PYR-GCK TVAAVGILFAHSD--------DAFGRIVHASLVAPVMSLWGLSTWG----
Mb1845|M.bovis_AF2122/97 PAQIVGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA------------
Rv1815|M.tuberculosis_H37Rv PAQIVGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA------------
TH_2227|M.thermoresistible__bu QAVIIGMFNSTWGQFPAAVSWQSTTAQINDEIIKATAGT---------PA
Mvan_3169|M.vanbaalenii_PYR-1 RTVLVGLFNSTWGTLPAAISWQVASQMAEADTISAASAV---------VA
MAB_2805c|M.abscessus_ATCC_199 QALLVGIYSLRWGGKPAAMSWSAISAQMQSQLVAQMPAAGPGNGGPELPA
MSMEG_6359|M.smegmatis_MC2_155 EVAAVGILRGSPEGEDNITEFSLLAPILEATSSSLFCDDPTCRGNGS---
MLBr_02242|M.leprae_Br4923 IVSAVGILMSSPEGDDHTTYFVPMPPLLEKRGLQSFPEVLKRLSPRLVGW
. :*:
MMAR_2300|M.marinum_M P----------
MUL_1503|M.ulcerans_Agy99 P----------
MAV_3280|M.avium_104 PR---------
Mflv_0488|M.gilvum_PYR-GCK -----------
Mb1845|M.bovis_AF2122/97 -----------
Rv1815|M.tuberculosis_H37Rv -----------
TH_2227|M.thermoresistible__bu AAA--------
Mvan_3169|M.vanbaalenii_PYR-1 PQP--------
MAB_2805c|M.abscessus_ATCC_199 PPTPAAVSAAS
MSMEG_6359|M.smegmatis_MC2_155 -----------
MLBr_02242|M.leprae_Br4923 GSGS-------