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SGRSSSRVLHLLFAVLAPVLALALQTVPAQAQPGVLVFPGMEIHQDTVLCTLGYVDPQTRIGYTAGHCRA SGTVSDKFGTMIGTQGTFRDNTPDGMTVDTNHQIIDWEVIHLAPHVAVNNVLPGGKVLVTDPAVLPVRGM PVCHFGVVTGESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDGRTVLVGLFNSTWGTLPAAISWQ VASQMAEADTISAASAVVAPQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3169 | - | - | 100% (233) | hypothetical protein Mvan_3169 |
| M. vanbaalenii PYR-1 | Mvan_5427 | - | 3e-10 | 30.19% (212) | peptidase S1 and S6, chymotrypsin/Hap |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1845 | - | 1e-61 | 53.05% (213) | hypothetical protein Mb1845 |
| M. gilvum PYR-GCK | Mflv_3416 | - | 1e-112 | 81.43% (237) | hypothetical protein Mflv_3416 |
| M. tuberculosis H37Rv | Rv1815 | - | 6e-61 | 52.58% (213) | hypothetical protein Rv1815 |
| M. leprae Br4923 | MLBr_02295 | - | 1e-09 | 27.40% (208) | hypothetical protein MLBr_02295 |
| M. abscessus ATCC 19977 | MAB_2805c | - | 1e-44 | 41.51% (212) | hypothetical protein MAB_2805c |
| M. marinum M | MMAR_2692 | - | 6e-59 | 52.66% (207) | hypothetical protein MMAR_2692 |
| M. avium 104 | MAV_2901 | - | 4e-64 | 55.29% (208) | hypothetical protein MAV_2901 |
| M. smegmatis MC2 155 | MSMEG_3661 | - | 1e-76 | 60.65% (216) | hypothetical protein MSMEG_3661 |
| M. thermoresistible (build 8) | TH_2227 | - | 3e-78 | 62.33% (215) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1916 | - | 3e-29 | 32.73% (220) | hypothetical protein MUL_1916 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1845|M.bovis_AF2122/97 --------MVR-LVPRAFAATVALLAAGFS-PATASADPVLVFPGMEIRQ
Rv1815|M.tuberculosis_H37Rv --------MVR-LVPRAFAATVALLAAGFS-PATASADPVLVFPGMEIRQ
MAV_2901|M.avium_104 --------MHR-LATRAFAASITVTALAATLPASAAKADVMVYPGMEIRQ
MMAR_2692|M.marinum_M --------MVRRLALRAFAVSATTAALAFAWAPAARAEPPLVFPGMEIHQ
Mvan_3169|M.vanbaalenii_PYR-1 MSGRSSS----RVLHLLFAVLAPVLALALQTVPAQAQPGVLVFPGMEIHQ
Mflv_3416|M.gilvum_PYR-GCK MSGRTSRQSPRRLLQLLMVLVAPLLVVTLGAPVAQAQPGVLVSPGMEIHQ
MSMEG_3661|M.smegmatis_MC2_155 MR--------QLLSHTLRALPVFFMMAALSAWPSHADPGVQVFPGMEIRQ
TH_2227|M.thermoresistible__bu -----------MVLAPLAAL-------TLASAPAHSSPGVVVHPGMEIHQ
MAB_2805c|M.abscessus_ATCC_199 ----------MSAVAAVAGVLVASPALSIADPAAETAPKIVAFPGMSIVQ
MUL_1916|M.ulcerans_Agy99 ---------MYHRWCRAAIAVVFVLVSVETPALGRAAVGVTAYPGLEIHQ
MLBr_02295|M.leprae_Br4923 ---MVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVING
.*: *
Mb1845|M.bovis_AF2122/97 D--NHVCTLGYVDPALKIAFTAGHCRGGG-AVTSRDYKVIGHLRAFRDNT
Rv1815|M.tuberculosis_H37Rv D--NHVCTLGYVDPALKIAFTAGHCRGGG-AVTSRDYKVIGHLRAIRDNT
MAV_2901|M.avium_104 D--NRVCTLGYVDPGLKIAFTAGHCRGGGGVVTDRGGTVIGRMAAFRDNT
MMAR_2692|M.marinum_M D--NHVCTLAWVDPAMHMAFTAGHCRGDG-PVTDRGNAIIGQLRAFRDNT
Mvan_3169|M.vanbaalenii_PYR-1 D--TVLCTLGYVDPQTRIGYTAGHCRASG-TVSDKFGTMIGTQGTFRDNT
Mflv_3416|M.gilvum_PYR-GCK D--SVLCTLGYVDPGTRIAYTAGHCRASG-TVSDKFGTPIGTQGSFRDNT
MSMEG_3661|M.smegmatis_MC2_155 D--SNLCTIGFIDPVARVAFTAGHCRGSG-SVGDRNGNFIGMQAAFHDNT
TH_2227|M.thermoresistible__bu D--TNSCTLGFIDAVRRIAYTAGHCRGSG-TVTDRAGRFIGTQLMFRDNT
MAB_2805c|M.abscessus_ATCC_199 G--DSRCTLGYVDPVSRIGLTAGHCNATG-SIVDLAGNRLGEVLLMSRNL
MUL_1916|M.ulcerans_Agy99 G--SVVCVIGFVEPQMRIAFSAGRCNGDP-MVTDRYGNAVGAVTLAGQAT
MLBr_02295|M.leprae_Br4923 DTMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGN
. .:. .. :. ::.:* . : *
Mb1845|M.bovis_AF2122/97 PSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAV
Rv1815|M.tuberculosis_H37Rv PSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAV
MAV_2901|M.avium_104 PSGTTVSTSQVINDYEAIVLDNGVTANNILPGGRPLVSDPGLALTPGQPV
MMAR_2692|M.marinum_M PSGTTVATDQTIEDYEAIMLVDGVRISNIMPGGRPLTSTPGLALQPGQAV
Mvan_3169|M.vanbaalenii_PYR-1 PDGMTVDTNHQIIDWEVIHLAPHVAVNNVLPGGKVLVTDPAVLPVRGMPV
Mflv_3416|M.gilvum_PYR-GCK PDGMTVDTNHQITDWEVIHLNQDVVINNVLPSGKALVTDPSVLPVKGMPV
MSMEG_3661|M.smegmatis_MC2_155 PNGATVDTNHVISDWETIQLAGDVGINPALPTGRILVEDPAIGAAPGMPV
TH_2227|M.thermoresistible__bu PNGSTVATDHQIADWQTIQLAGDVVMNNVLPTGRVLVEDPTVVPQPGQPV
MAB_2805c|M.abscessus_ATCC_199 PTGGAIGPGDVVSDYEGISFGPGVELSSNLPNGLALRMAQNAGPELGLPV
MUL_1916|M.ulcerans_Agy99 VSEVAVDGAAAGVDYEVITLAPEVAATDLLPTGLRLQSKPGFRVQPGARV
MLBr_02295|M.leprae_Br4923 DN----------LDYAVIKFDPAKVMPVAAYNG-FVISGIGQDPAFGQIA
*: * : * : * .
Mb1845|M.bovis_AF2122/97 CHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQI
Rv1815|M.tuberculosis_H37Rv CHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQI
MAV_2901|M.avium_104 CHFGVITGETCGTVESVNNGWFTMSHGVQSHNGDSGGPVYLAPSGGPGQI
MMAR_2692|M.marinum_M CHFGITTGETCGTVESVNNGWFTMTGGVESQRGDSGGPVYLAG-AGPGQL
Mvan_3169|M.vanbaalenii_PYR-1 CHFGVVTGESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDGRTVL
Mflv_3416|M.gilvum_PYR-GCK CHFGVVTGESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDGRTVL
MSMEG_3661|M.smegmatis_MC2_155 CHFGVVTGESCGTVEAVNNGWFTMANGVVSARGDSGGSVYTVTPDGRAVI
TH_2227|M.thermoresistible__bu CHFGVVTGESCGRIAAVNNGWFTMGDGVVSQKGDSGGPVYTVNEAGQAVI
MAB_2805c|M.abscessus_ATCC_199 CLMGSVSGETCGKVEAINNGWFTMVD-VAGQHGDSGGPVYTVTQPGQALL
MUL_1916|M.ulcerans_Agy99 CEATAAR-QRCGRVDTVTESRFVIAG-MDADQHEIGAPVYVLDDDNHALI
MLBr_02295|M.leprae_Br4923 CKQGRTTGNSCGVAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIH
* : ** : : .: : . : *..*
Mb1845|M.bovis_AF2122/97 VGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA----------------
Rv1815|M.tuberculosis_H37Rv VGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA----------------
MAV_2901|M.avium_104 VGIFNSVWGEYPAAVSWQATSEEVREDLGVRDNAR---------------
MMAR_2692|M.marinum_M VGIFNSIWGDFPAAVSWQRTSDEMRQDLGVPFAG----------------
Mvan_3169|M.vanbaalenii_PYR-1 VGLFNSTWGTLPAAISWQVASQMAEADTISAASAV------------VAP
Mflv_3416|M.gilvum_PYR-GCK IGLFNSTWGTFPAAISWEVASRQAQADTISAASAV------------VTP
MSMEG_3661|M.smegmatis_MC2_155 LGLFNSTWGQYPAAVSWPSVSGAARHTIVQASADS------------ADL
TH_2227|M.thermoresistible__bu IGMFNSTWGQFPAAVSWQSTTAQINDEIIKATAGT------------PAA
MAB_2805c|M.abscessus_ATCC_199 VGIYSLRWGGKPAAMSWSAISAQMQSQLVAQMPAAGPGNGGPELPAPPTP
MUL_1916|M.ulcerans_Agy99 AGLLDGVRGSISEAQSWPAVMRQVYLDSRSVDSTQ------------PPP
MLBr_02295|M.leprae_Br4923 GAFTDNLPVCITKFIPLHTPAVVMSMNAILADVNKN---------NRPGA
.: . . .
Mb1845|M.bovis_AF2122/97 -------
Rv1815|M.tuberculosis_H37Rv -------
MAV_2901|M.avium_104 -------
MMAR_2692|M.marinum_M -------
Mvan_3169|M.vanbaalenii_PYR-1 QP-----
Mflv_3416|M.gilvum_PYR-GCK EPVTP--
MSMEG_3661|M.smegmatis_MC2_155 FVQ----
TH_2227|M.thermoresistible__bu AA-----
MAB_2805c|M.abscessus_ATCC_199 AAVSAAS
MUL_1916|M.ulcerans_Agy99 QGRTIGS
MLBr_02295|M.leprae_Br4923 GFVPQPV