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VVRLVPRAFAATVALLAAGFSPATASADPVLVFPGMEIRQDNHVCTLGYVDPALKIAFTAGHCRGGGAVT SRDYKVIGHLRAIRDNTPSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAVCHF GVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQIVGIFNSVWGGFPAAVSWRSTSEQ VHADLGVTPLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1815 | - | - | 100% (221) | hypothetical protein Rv1815 |
| M. tuberculosis H37Rv | Rv3668c | - | 1e-05 | 30.56% (180) | protease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1845 | - | 1e-127 | 99.55% (221) | hypothetical protein Mb1845 |
| M. gilvum PYR-GCK | Mflv_3416 | - | 1e-61 | 53.52% (213) | hypothetical protein Mflv_3416 |
| M. leprae Br4923 | MLBr_02295 | - | 2e-06 | 29.31% (174) | hypothetical protein MLBr_02295 |
| M. abscessus ATCC 19977 | MAB_2805c | - | 4e-42 | 41.86% (215) | hypothetical protein MAB_2805c |
| M. marinum M | MMAR_2692 | - | 1e-82 | 68.49% (219) | hypothetical protein MMAR_2692 |
| M. avium 104 | MAV_2901 | - | 1e-86 | 71.69% (219) | hypothetical protein MAV_2901 |
| M. smegmatis MC2 155 | MSMEG_3661 | - | 4e-61 | 55.50% (200) | hypothetical protein MSMEG_3661 |
| M. thermoresistible (build 8) | TH_2227 | - | 1e-64 | 56.59% (205) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1916 | - | 2e-30 | 35.41% (209) | hypothetical protein MUL_1916 |
| M. vanbaalenii PYR-1 | Mvan_3169 | - | 8e-61 | 52.58% (213) | hypothetical protein Mvan_3169 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1815|M.tuberculosis_H37Rv --------MVR-LVPRAFAATVALLAAGFS-PATASADPVLVFPGMEIRQ
Mb1845|M.bovis_AF2122/97 --------MVR-LVPRAFAATVALLAAGFS-PATASADPVLVFPGMEIRQ
MAV_2901|M.avium_104 --------MHR-LATRAFAASITVTALAATLPASAAKADVMVYPGMEIRQ
MMAR_2692|M.marinum_M --------MVRRLALRAFAVSATTAALAFAWAPAARAEPPLVFPGMEIHQ
MSMEG_3661|M.smegmatis_MC2_155 MR--------QLLSHTLRALPVFFMMAALSAWPSHADPGVQVFPGMEIRQ
TH_2227|M.thermoresistible__bu -----------MVLAPLAAL-------TLASAPAHSSPGVVVHPGMEIHQ
Mflv_3416|M.gilvum_PYR-GCK MSGRTSRQSPRRLLQLLMVLVAPLLVVTLGAPVAQAQPGVLVSPGMEIHQ
Mvan_3169|M.vanbaalenii_PYR-1 MSGRSSS----RVLHLLFAVLAPVLALALQTVPAQAQPGVLVFPGMEIHQ
MAB_2805c|M.abscessus_ATCC_199 ----------MSAVAAVAGVLVASPALSIADPAAETAPKIVAFPGMSIVQ
MUL_1916|M.ulcerans_Agy99 ---------MYHRWCRAAIAVVFVLVSVETPALGRAAVGVTAYPGLEIHQ
MLBr_02295|M.leprae_Br4923 ---MVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVING
.*: *
Rv1815|M.tuberculosis_H37Rv D--NHVCTLGYVDPALKIAFTAGHCRGGG-AVTSRDYKVIGHLRAIRDNT
Mb1845|M.bovis_AF2122/97 D--NHVCTLGYVDPALKIAFTAGHCRGGG-AVTSRDYKVIGHLRAFRDNT
MAV_2901|M.avium_104 D--NRVCTLGYVDPGLKIAFTAGHCRGGGGVVTDRGGTVIGRMAAFRDNT
MMAR_2692|M.marinum_M D--NHVCTLAWVDPAMHMAFTAGHCRGDG-PVTDRGNAIIGQLRAFRDNT
MSMEG_3661|M.smegmatis_MC2_155 D--SNLCTIGFIDPVARVAFTAGHCRGSG-SVGDRNGNFIGMQAAFHDNT
TH_2227|M.thermoresistible__bu D--TNSCTLGFIDAVRRIAYTAGHCRGSG-TVTDRAGRFIGTQLMFRDNT
Mflv_3416|M.gilvum_PYR-GCK D--SVLCTLGYVDPGTRIAYTAGHCRASG-TVSDKFGTPIGTQGSFRDNT
Mvan_3169|M.vanbaalenii_PYR-1 D--TVLCTLGYVDPQTRIGYTAGHCRASG-TVSDKFGTMIGTQGTFRDNT
MAB_2805c|M.abscessus_ATCC_199 G--DSRCTLGYVDPVSRIGLTAGHCNATG-SIVDLAGNRLGEVLLMSRNL
MUL_1916|M.ulcerans_Agy99 G--SVVCVIGFVEPQMRIAFSAGRCNGDP-MVTDRYGNAVGAVTLAGQAT
MLBr_02295|M.leprae_Br4923 DTMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGN
. .:. .. :. ::.:* . : *
Rv1815|M.tuberculosis_H37Rv PSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAV
Mb1845|M.bovis_AF2122/97 PSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAV
MAV_2901|M.avium_104 PSGTTVSTSQVINDYEAIVLDNGVTANNILPGGRPLVSDPGLALTPGQPV
MMAR_2692|M.marinum_M PSGTTVATDQTIEDYEAIMLVDGVRISNIMPGGRPLTSTPGLALQPGQAV
MSMEG_3661|M.smegmatis_MC2_155 PNGATVDTNHVISDWETIQLAGDVGINPALPTGRILVEDPAIGAAPGMPV
TH_2227|M.thermoresistible__bu PNGSTVATDHQIADWQTIQLAGDVVMNNVLPTGRVLVEDPTVVPQPGQPV
Mflv_3416|M.gilvum_PYR-GCK PDGMTVDTNHQITDWEVIHLNQDVVINNVLPSGKALVTDPSVLPVKGMPV
Mvan_3169|M.vanbaalenii_PYR-1 PDGMTVDTNHQIIDWEVIHLAPHVAVNNVLPGGKVLVTDPAVLPVRGMPV
MAB_2805c|M.abscessus_ATCC_199 PTGGAIGPGDVVSDYEGISFGPGVELSSNLPNGLALRMAQNAGPELGLPV
MUL_1916|M.ulcerans_Agy99 VSEVAVDGAAAGVDYEVITLAPEVAATDLLPTGLRLQSKPGFRVQPGARV
MLBr_02295|M.leprae_Br4923 DN----------LDYAVIKFDPAKVMPVAAYNG-FVISGIGQDPAFGQIA
*: * : * : * .
Rv1815|M.tuberculosis_H37Rv CHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQI
Mb1845|M.bovis_AF2122/97 CHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQI
MAV_2901|M.avium_104 CHFGVITGETCGTVESVNNGWFTMSHGVQSHNGDSGGPVYLAPSGGPGQI
MMAR_2692|M.marinum_M CHFGITTGETCGTVESVNNGWFTMTGGVESQRGDSGGPVYLAG-AGPGQL
MSMEG_3661|M.smegmatis_MC2_155 CHFGVVTGESCGTVEAVNNGWFTMANGVVSARGDSGGSVYTVTPDGRAVI
TH_2227|M.thermoresistible__bu CHFGVVTGESCGRIAAVNNGWFTMGDGVVSQKGDSGGPVYTVNEAGQAVI
Mflv_3416|M.gilvum_PYR-GCK CHFGVVTGESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDGRTVL
Mvan_3169|M.vanbaalenii_PYR-1 CHFGVVTGESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTPTPDGRTVL
MAB_2805c|M.abscessus_ATCC_199 CLMGSVSGETCGKVEAINNGWFTMVD-VAGQHGDSGGPVYTVTQPGQALL
MUL_1916|M.ulcerans_Agy99 CEATAAR-QRCGRVDTVTESRFVIAG-MDADQHEIGAPVYVLDDDNHALI
MLBr_02295|M.leprae_Br4923 CKQGRTTGNSCGVAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIH
* : ** : : .: : . : *..*
Rv1815|M.tuberculosis_H37Rv VGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA----------------
Mb1845|M.bovis_AF2122/97 VGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA----------------
MAV_2901|M.avium_104 VGIFNSVWGEYPAAVSWQATSEEVREDLGVRDNAR---------------
MMAR_2692|M.marinum_M VGIFNSIWGDFPAAVSWQRTSDEMRQDLGVPFAG----------------
MSMEG_3661|M.smegmatis_MC2_155 LGLFNSTWGQYPAAVSWPSVSGAARHTIVQASADS------------ADL
TH_2227|M.thermoresistible__bu IGMFNSTWGQFPAAVSWQSTTAQINDEIIKATAGT------------PAA
Mflv_3416|M.gilvum_PYR-GCK IGLFNSTWGTFPAAISWEVASRQAQADTISAASAV------------VTP
Mvan_3169|M.vanbaalenii_PYR-1 VGLFNSTWGTLPAAISWQVASQMAEADTISAASAV------------VAP
MAB_2805c|M.abscessus_ATCC_199 VGIYSLRWGGKPAAMSWSAISAQMQSQLVAQMPAAGPGNGGPELPAPPTP
MUL_1916|M.ulcerans_Agy99 AGLLDGVRGSISEAQSWPAVMRQVYLDSRSVDSTQ------------PPP
MLBr_02295|M.leprae_Br4923 GAFTDNLPVCITKFIPLHTPAVVMSMNAILADVNKN---------NRPGA
.: . . .
Rv1815|M.tuberculosis_H37Rv -------
Mb1845|M.bovis_AF2122/97 -------
MAV_2901|M.avium_104 -------
MMAR_2692|M.marinum_M -------
MSMEG_3661|M.smegmatis_MC2_155 FVQ----
TH_2227|M.thermoresistible__bu AA-----
Mflv_3416|M.gilvum_PYR-GCK EPVTP--
Mvan_3169|M.vanbaalenii_PYR-1 QP-----
MAB_2805c|M.abscessus_ATCC_199 AAVSAAS
MUL_1916|M.ulcerans_Agy99 QGRTIGS
MLBr_02295|M.leprae_Br4923 GFVPQPV