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MVSVDALELASWGTPYSPARTVALPLGALVLAVLAVLGFLPGRAERRRKPATGAFPATDVLPPRPRTHTT VLTLAAVCSITALVAAVCLLPSAATPAQQPTPPPVLAPIDLPAASAIGPGAGIYVDYTDGSGGMGCTAGF LVHTSSGQAGILTAGHCNRSGEPSKVTMNLGGVLPYATLGTFSQTISEGVHDEQHDIGLITLDGDNVPQS PAIAASVPVSGVAANLQVGQQLCKFGMGSGADACGQIVEITGSKVKFLAGGQCGDSGGPVYRYENDGTVS AVGILIRGGDPYTRKAGCAARAKFSVAELVRPWLDTWRLTMVTAASAPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3280 | - | - | 100% (329) | hypothetical protein MAV_3280 |
| M. avium 104 | MAV_0678 | - | 4e-17 | 30.49% (246) | hypothetical protein MAV_0678 |
| M. avium 104 | MAV_2901 | - | 6e-06 | 29.68% (155) | hypothetical protein MAV_2901 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1845 | - | 3e-06 | 26.17% (214) | hypothetical protein Mb1845 |
| M. gilvum PYR-GCK | Mflv_0488 | - | 4e-20 | 34.47% (235) | hypothetical protein Mflv_0488 |
| M. tuberculosis H37Rv | Rv1815 | - | 2e-06 | 26.17% (214) | hypothetical protein Rv1815 |
| M. leprae Br4923 | MLBr_02242 | - | 9e-10 | 31.10% (164) | hypothetical protein MLBr_02242 |
| M. abscessus ATCC 19977 | MAB_3349 | - | 1e-09 | 30.18% (222) | hypothetical protein MAB_3349 |
| M. marinum M | MMAR_2300 | - | 3e-86 | 51.20% (332) | hypothetical protein MMAR_2300 |
| M. smegmatis MC2 155 | MSMEG_6359 | - | 8e-14 | 30.89% (259) | trypsin domain-containing protein |
| M. thermoresistible (build 8) | TH_2227 | - | 2e-07 | 29.90% (194) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1503 | - | 6e-81 | 56.18% (267) | hypothetical protein MUL_1503 |
| M. vanbaalenii PYR-1 | Mvan_3169 | - | 2e-07 | 28.65% (192) | hypothetical protein Mvan_3169 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2300|M.marinum_M MVGVSAHALANLDSPSSLARTALLLAGALLCLSVAAWPVLSQRRRQHPET
MUL_1503|M.ulcerans_Agy99 --------------------------------------------------
MAV_3280|M.avium_104 MVSVDALELASWGTPYSPARTVALPLGALVLAVLAVLGFLPGRAERRRKP
Mflv_0488|M.gilvum_PYR-GCK --------------------------------------------------
Mb1845|M.bovis_AF2122/97 --------------------------------------------------
Rv1815|M.tuberculosis_H37Rv --------------------------------------------------
TH_2227|M.thermoresistible__bu --------------------------------------------------
Mvan_3169|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3349|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6359|M.smegmatis_MC2_155 ---------------------------------------------MTGGV
MLBr_02242|M.leprae_Br4923 --------------------------------------------------
MMAR_2300|M.marinum_M QEQLFAGTNVPYAAPPQRRQSDGGRLTIAALICAAGFVAAIWLPSKSTMP
MUL_1503|M.ulcerans_Agy99 ---MFAGTNVPYAAPPQRRQSDGGRLTIAALICAAGFVAAVWLPSKSTMP
MAV_3280|M.avium_104 ATGAFPATDV----LPPRPRTHTTVLTLAAVCSITALVAAVCLLPSAATP
Mflv_0488|M.gilvum_PYR-GCK ---------------MMRNLLKTVGGTAAAALAALTFTQAPVAHAFGEYP
Mb1845|M.bovis_AF2122/97 --------------------------MVRLVPRAFAATVALLAAGFSPAT
Rv1815|M.tuberculosis_H37Rv --------------------------MVRLVPRAFAATVALLAAGFSPAT
TH_2227|M.thermoresistible__bu -----------------------------------MVLAPLAALTLASAP
Mvan_3169|M.vanbaalenii_PYR-1 ---------------------MSGRSSSRVLHLLFAVLAPVLALALQTVP
MAB_3349|M.abscessus_ATCC_1997 --------------------------MRPFLWIATIVAVLCVLPAVNPAP
MSMEG_6359|M.smegmatis_MC2_155 YAPVPPGVPAPTPTPVKPRRRILRRLLITSLGLATVLAVAFVAFVFWPNP
MLBr_02242|M.leprae_Br4923 -------------MRSIYWFTGETCATVRWLRGLGLASAAVIAPKVFASM
MMAR_2300|M.marinum_M ARP-------------LVALPGASAIAPGTGIAVTYADGSGG-MGCTAGF
MUL_1503|M.ulcerans_Agy99 ARP-------------LVALPGASAIAPGTGIAVTYADGSGG-MGCTAGF
MAV_3280|M.avium_104 AQQPTPP-----PVLAPIDLPAASAIGPGAGIYVDYTDGSGG-MGCTAGF
Mflv_0488|M.gilvum_PYR-GCK VAS------------------------PGAHLVSTTLAGNGLPYQCTAGF
Mb1845|M.bovis_AF2122/97 ASADP------------------VLVFPGMEIRQDNHV-------CTLGY
Rv1815|M.tuberculosis_H37Rv ASADP------------------VLVFPGMEIRQDNHV-------CTLGY
TH_2227|M.thermoresistible__bu AHSSPG-----------------VVVHPGMEIHQDTNS-------CTLGF
Mvan_3169|M.vanbaalenii_PYR-1 AQAQPG-----------------VLVFPGMEIHQDTVL-------CTLGY
MAB_3349|M.abscessus_ATCC_1997 VHAEP------------------PLVYPGMLIYQGSLS-------CTLGY
MSMEG_6359|M.smegmatis_MC2_155 TVPADQPNMTQVMTGTDNDWLSFDDFVPGTAIAADGSDNDE--YECTLGF
MLBr_02242|M.leprae_Br4923 VLAEYAP-------------------SPGLRLCDESSI-------CTAAC
. ** : ** .
MMAR_2300|M.marinum_M LVRTNAGRTGILTAGHCNKEGEASKVS-INYSAGGGYVNIG--------T
MUL_1503|M.ulcerans_Agy99 LVRTNAGRTGILTAGHCNKEGEASKVS-INYSTGGGYVNIG--------T
MAV_3280|M.avium_104 LVHTSSGQAGILTAGHCNRSGEPSKVT-MNLGGVLPYATLG--------T
Mflv_0488|M.gilvum_PYR-GCK TVRTPGGSPGMLTAGHCDRDPLNDTVL-QRTPTGDRVVGRY--------V
Mb1845|M.bovis_AF2122/97 VDPALKIA---FTAGHCR-GGGAVTSR-DYKVIGHLRAFRD--------N
Rv1815|M.tuberculosis_H37Rv VDPALKIA---FTAGHCR-GGGAVTSR-DYKVIGHLRAIRD--------N
TH_2227|M.thermoresistible__bu IDAVRRIA---YTAGHCR-GSGTVTDR-AGRFIGTQLMFRD--------N
Mvan_3169|M.vanbaalenii_PYR-1 VDPQTRIG---YTAGHCR-ASGTVSDK-FGTMIGTQGTFRD--------N
MAB_3349|M.abscessus_ATCC_1997 VDPALRVG---ITAGHCFNGDGIIRNG-DGAAVGHKVLAHD--------N
MSMEG_6359|M.smegmatis_MC2_155 LGRDSSGTPIGFTAGHCDRPGDDSPHF-TRKADEDTPVELGRFTTVQTAD
MLBr_02242|M.leprae_Br4923 VARGNDGSSYLLTIGHCDAYDGSVWPYGPDVPLGKRTVSEN---------
* ***
MMAR_2300|M.marinum_M FSQSVSEGLNGEAHDIGLITLDSGKIP----QSPAIKAAVPVTGIATD--
MUL_1503|M.ulcerans_Agy99 FSQSVSEGLNGEAHDIGLITLDSGKIP----QSPAIKAAVPVTGIATD--
MAV_3280|M.avium_104 FSQTISEGVHDEQHDIGLITLDGDNVP----QSPAIAASVPVSGVAAN--
Mflv_0488|M.gilvum_PYR-GCK RWEVLPG-----VRDVGLVDLAGSSVP----LVDQVDGMRVSRVMSGDDV
Mb1845|M.bovis_AF2122/97 TPSGSTVATHELIADYEAIVLADDVTA----SNILPSGRALESRPGVVL-
Rv1815|M.tuberculosis_H37Rv TPSGSTVATHELIADYEAIVLADDVTA----SNILPSGRALESRPGVVL-
TH_2227|M.thermoresistible__bu TPNGSTVATDHQIADWQTIQLAGDVVM----NNVLPTGRVLVEDPTVVP-
Mvan_3169|M.vanbaalenii_PYR-1 TPDGMTVDTNHQIIDWEVIHLAPHVAV----NNVLPGGKVLVTDPAVLP-
MAB_3349|M.abscessus_ATCC_1997 RPPEGPVYENEYTIDYEAISIDDGLPV----NDVLANGQRLERDDTVIP-
MSMEG_6359|M.smegmatis_MC2_155 MPDKVVKTGPDGWSDFAVIEIDPSLTDSAEDNARIAGVYRVTKVLDYEYL
MLBr_02242|M.leprae_Br4923 ---------EGDRKDAAIILLDLSQGY----SSGDVYSQLLRNVLSENE-
* : :
MMAR_2300|M.marinum_M LKVGQLLCKFGMKTGRAECGQVTDISASKVAFL--AASECGDSGGPVYRL
MUL_1503|M.ulcerans_Agy99 LKVGQLLCKFGMKTGRAECGQVTDISASKVAFL--AASECGDSGGPVYRL
MAV_3280|M.avium_104 LQVGQQLCKFGMGSGADACGQIVEITGSKVKFL--AGGQCGDSGGPVYRY
Mflv_0488|M.gilvum_PYR-GCK RREQPELCKSGARTG-LSCGPVTSVTDNQVSFR--AWDDLGDSGAPVYAR
Mb1845|M.bovis_AF2122/97 -HPGQAVCHFGVSTG-ETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLA
Rv1815|M.tuberculosis_H37Rv -HPGQAVCHFGVSTG-ETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLA
TH_2227|M.thermoresistible__bu -QPGQPVCHFGVVTG-ESCGRIAAVNNGWFTMGDGVVSQKGDSGGPVYTV
Mvan_3169|M.vanbaalenii_PYR-1 -VRGMPVCHFGVVTG-ESCGTIESVNNGWFTMANGVVSRKGDSGGPVYTP
MAB_3349|M.abscessus_ATCC_1997 -DVGMPVCRTGFTTG-DACGSVTRIGNGWFRFN-GPVIAKGDSGGPVYTH
MSMEG_6359|M.smegmatis_MC2_155 LNNNVTLCKFGFVSG-ETCGKVIGHDN--LTVEAELYSASGDSGSPAYVK
MLBr_02242|M.leprae_Br4923 IQLGMLFCKVGAITG-ETCGTIKSMDGDVVEAS--VYSLSAGSGSPGFVK
.*: * :* ** : . ..**.* :
MMAR_2300|M.marinum_M DDDGTAVAVGILIR--AGHANDPHPGCSTPATFSIAELVRPWLDRWSLTA
MUL_1503|M.ulcerans_Agy99 DDDGTAVAVGILIR--AGHANDPHPGCSTPATFSIAELVRPWLDRWSLTA
MAV_3280|M.avium_104 ENDGTVSAVGILIR--GGDPYTRKAGCAARAKFSVAELVRPWLDTWRLTM
Mflv_0488|M.gilvum_PYR-GCK QPDGTVAAVGILFA--HSD--------DAFGRIVHASLVAPVMSLWGLST
Mb1845|M.bovis_AF2122/97 PDGGPAQIVGIFN--SVWGGFPAAVSWRSTSEQVHADLGVTPLA------
Rv1815|M.tuberculosis_H37Rv PDGGPAQIVGIFN--SVWGGFPAAVSWRSTSEQVHADLGVTPLA------
TH_2227|M.thermoresistible__bu NEAGQAVIIGMFN--STWGQFPAAVSWQSTTAQINDEIIKATAGTPAAAA
Mvan_3169|M.vanbaalenii_PYR-1 TPDGRTVLVGLFN--STWGTLPAAISWQVASQMAEADTISAASAVVAPQP
MAB_3349|M.abscessus_ATCC_1997 VG-DRTVLVGIIRGFMTSQSGDDVQSWAMSWPSVIKQLREDRKGLLPA--
MSMEG_6359|M.smegmatis_MC2_155 FGNDEVAAVGILRG--SPEGEDNITEFSLLAPILEATSSSLFCDDPTCRG
MLBr_02242|M.leprae_Br4923 NVDGIVSAVGILMS--SPEGDDHTTYFVPMPPLLEKRGLQSFPEVLKRLS
. . :*::
MMAR_2300|M.marinum_M ITEPGSP---
MUL_1503|M.ulcerans_Agy99 ITEPGSP---
MAV_3280|M.avium_104 VTAASAPR--
Mflv_0488|M.gilvum_PYR-GCK WG--------
Mb1845|M.bovis_AF2122/97 ----------
Rv1815|M.tuberculosis_H37Rv ----------
TH_2227|M.thermoresistible__bu ----------
Mvan_3169|M.vanbaalenii_PYR-1 ----------
MAB_3349|M.abscessus_ATCC_1997 ----------
MSMEG_6359|M.smegmatis_MC2_155 NGS-------
MLBr_02242|M.leprae_Br4923 PRLVGWGSGS