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MGSASEVIDVRDLTFTYPRAAEPAVRGMDFAVGNGEIFGFLGPSGAGKSTTQKLLIGLLRGHGGQALVWG RDPVDWGQDYYQRVGVSFELPNHYLRLTGLENLQFFASLYEKQTEDPMELLHAVGLADAAYTRVGEYSKG MQMRLTFARSLINKPELLFLDEPTSGLDPVNARRVKEIVLDLKSKGRTIFLTTHDMSTADELCDRIAFVV DGSIVALDTPAELKIARSRRRVRVQYRVADGGLRTAEFGMDGLADDPEFHAVLRDHHVETIHSREASLDD VFVEVTGRQLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1502 | - | - | 100% (291) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6766 | - | 2e-39 | 41.55% (219) | ABC transporter, ATP-binding protein, NodI family protein |
| M. smegmatis MC2 155 | MSMEG_3119 | - | 3e-33 | 33.80% (287) | ABC transporter, ATP-binding subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2707c | - | 1e-135 | 81.12% (286) | antibiotic ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_3680 | - | 4e-37 | 33.01% (309) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2688c | - | 1e-134 | 80.77% (286) | antibiotic ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 3e-33 | 32.87% (289) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1858 | - | 1e-126 | 76.31% (287) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2026 | - | 1e-130 | 76.21% (290) | antibiotic-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3321 | - | 2e-34 | 33.79% (290) | ABC transporter, ATP-binding subunit |
| M. thermoresistible (build 8) | TH_2745 | - | 2e-27 | 29.93% (284) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_1859 | - | 1e-34 | 33.91% (289) | antibiotic ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_0776 | - | 1e-138 | 82.01% (289) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3321|M.avium_104 -----------------MRLRGVSKHYG--STTAVRDLDLEVHAAEVLAL
MUL_1859|M.ulcerans_Agy99 ----------------MVRLRGVGKQYG--SVTAVSNLDLEVRAAEVMAL
MLBr_00590|M.leprae_Br4923 ---MSSACTVPETPEVVIRLRGVCKHYG--SILAVSNLDLDIHSAEVLAL
Mflv_3680|M.gilvum_PYR-GCK MTSVSPGAVPDGSPSAPVVLRGVSKRYG--STTAVAGLDLVVERAEVFAL
MSMEG_1502|M.smegmatis_MC2_155 ----------MGSASEVIDVRDLTFTYPRAAEPAVRGMDFAVGNGEIFGF
Mvan_0776|M.vanbaalenii_PYR-1 ----------MNTES-VIDVRDLTYTYPKTAEPAVRGMDFAVGRGEIFGF
Mb2707c|M.bovis_AF2122/97 MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
Rv2688c|M.tuberculosis_H37Rv MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
MAB_1858|M.abscessus_ATCC_1997 -------------MTEVIQVRELTFTYPKTPEPAVRGMDFTVGEGEIFGF
MMAR_2026|M.marinum_M --MRDPEPAVSGAVGEVIRVRGLTFAYPKASTPAVRGMDFSVGRGEIFGF
TH_2745|M.thermoresistible__bu ----MTTTSPRFDAEPAVEIHGLKKSFG--RTRAVDGLDLRVERGSVAGF
: :: : : ** .::: : ..: .:
MAV_3321|M.avium_104 LGPNGAGKTTTVEMCEGFVRPDAGTLEVLGLDPIADNARLRPRIGVMLQG
MUL_1859|M.ulcerans_Agy99 LGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQG
MLBr_00590|M.leprae_Br4923 LGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQG
Mflv_3680|M.gilvum_PYR-GCK LGPNGAGKTTTVEMCEGFIKPDAGSLRILGLDPIVDNAEVRARTGVMLQG
MSMEG_1502|M.smegmatis_MC2_155 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPVDWGQDYYQRVGVSFEL
Mvan_0776|M.vanbaalenii_PYR-1 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPLDWGPRYYQRIGVSFEL
Mb2707c|M.bovis_AF2122/97 LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
Rv2688c|M.tuberculosis_H37Rv LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
MAB_1858|M.abscessus_ATCC_1997 LGPSGAGKSTTQKLLIGLLRGHGGRATVWGREPGAWGRNYYQRIGVSFEL
MMAR_2026|M.marinum_M LGPSGAGKSTTQRILIGLLRGHGGEVAVWGKDPASWGSDYYERIGVSFEL
TH_2745|M.thermoresistible__bu LGPNGSGKSTTIRVLLGLLRADGGTARLLGGDPWHDAVELHRRLAYVPGD
***.*:**:** .: *::: ..* : . :* * .
MAV_3321|M.avium_104 GGGYPAARAGEMLNLVAAYAADP-LDPAWLLDTLGLTDAARTTYRRLSGG
MUL_1859|M.ulcerans_Agy99 GGGYPAARAGEMLDLVASYAADP-LDPRWLLDTLGLTDAARTTYRRLSGG
MLBr_00590|M.leprae_Br4923 GGGYPAARAGEMLNLVASYAADP-LDPEWLLETLGLTDVARTTYRRLSGG
Mflv_3680|M.gilvum_PYR-GCK GGAYPAARAGEMLDLVAAYAADP-LDPTWLLDTLGLTDAARTTYRRLSGG
MSMEG_1502|M.smegmatis_MC2_155 PNHYLRLTGLENLQFFASLYEKQTEDPMELLHAVGLADAAYTRVGEYSKG
Mvan_0776|M.vanbaalenii_PYR-1 PNHYLKLTGAENLQFFASLYDSAGPDPRSLLDDVGLTDAADTRVAKYSKG
Mb2707c|M.bovis_AF2122/97 PNHYQKLTGYENLRFFASLYAGATADPMQLLAAVGLADDAHTLVGKYSKG
Rv2688c|M.tuberculosis_H37Rv PNHYQKLTGYENLRFFASLYAGATADPMQLLAAVGLADDAHTLVGKYSKG
MAB_1858|M.abscessus_ATCC_1997 PNHYQKLTALENLRFFASLYAGPTRDPMELLDAVGLADDANTRVGAFSKG
MMAR_2026|M.marinum_M PNHYQKLTGLENLQFFASLYSAPTLDPMQLLEAVGLADHADTRAGKYSKG
TH_2745|M.thermoresistible__bu VTLWPNLTGGQAIDFLAGLRDNFDTKRRDELIER-FELDPDKKARTYSKG
: . : : :.*. . * : . . * *
MAV_3321|M.avium_104 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MUL_1859|M.ulcerans_Agy99 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MLBr_00590|M.leprae_Br4923 QQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVV
Mflv_3680|M.gilvum_PYR-GCK QQQRLALACAVVGRPELVFLDEPTAGMDAHARIVVWELIDALRRDGVTVV
MSMEG_1502|M.smegmatis_MC2_155 MQMRLTFARSLINKPELLFLDEPTSGLDPVNARRVKEIVLDLKSKGRTIF
Mvan_0776|M.vanbaalenii_PYR-1 MQMRLTFARSLVNDPELLFLDEPTSGLDPVNARRIKDIILDLKARGRTVF
Mb2707c|M.bovis_AF2122/97 MQMRLTFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARGRTIF
Rv2688c|M.tuberculosis_H37Rv MQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARGRTIF
MAB_1858|M.abscessus_ATCC_1997 MQMRLTFVRALINDPELLFLDEPTSGLDPVNARKVKDMVLELKARGRTIF
MMAR_2026|M.marinum_M MQMRLTFARALLNDPELLFLDEPTSGMDPVNARSVKNMIMDLKARGRTVF
TH_2745|M.thermoresistible__bu NRQKVALVAAFSTNAEIYILDEPTSGLDPLMDKAFQMCVREAADNGAAVL
: ::.:. :. .*: :*****:*:*. . : * ::.
MAV_3321|M.avium_104 LTTHQLKEAEELADRLVIIDHGATVAAGTPAELMRSGAKDQLRFSAPPRL
MUL_1859|M.ulcerans_Agy99 LTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLRFTAPPRL
MLBr_00590|M.leprae_Br4923 LTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRL
Mflv_3680|M.gilvum_PYR-GCK LTTHQLSEAEELADRILIIDNGAAVATGTPAELMRNGAENQLRFRAPKML
MSMEG_1502|M.smegmatis_MC2_155 LTTHDMSTADELCDRIAFVVDGSIVALDTPAELKIARSRRRVRVQYRV--
Mvan_0776|M.vanbaalenii_PYR-1 LTTHDMATADELCDRVAFVVDGRIVALDAPAELKIARSRRLVRVEYRS--
Mb2707c|M.bovis_AF2122/97 LTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEYRG--
Rv2688c|M.tuberculosis_H37Rv LTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEYRG--
MAB_1858|M.abscessus_ATCC_1997 ITTHAMSAADELCDRVAFVVDGRIVAMNSPAELKLEYGRRSVRVEYRG--
MMAR_2026|M.marinum_M LTTHDMATADELCDRVAFVVDGSIVVSDRPAELKIARSQRLVTVEYRG--
TH_2745|M.thermoresistible__bu LSSHILAEVERLCDSVTIIRSGRTVRAGRLDELR-HLMRTTVKVRTRAP-
:::* : .:.*.* : :: * : . ** . : .
MAV_3321|M.avium_104 DLSLLSAALPEDYKATELTPGEYLVEGPVDPQVLATVTAWCARIDVLATD
MUL_1859|M.ulcerans_Agy99 DLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCARIDVLATD
MLBr_00590|M.leprae_Br4923 DLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINVLTTN
Mflv_3680|M.gilvum_PYR-GCK DLSLLVAALPEGYRATEPTAGEYLVEGHIDPQVLATVTAWCARLDVLATD
MSMEG_1502|M.smegmatis_MC2_155 -------------ADGGLRTAEFGMDGLADDPEFHAVLR-----DHHVET
Mvan_0776|M.vanbaalenii_PYR-1 -------------AQGTLQTTEFPMDGLADDPEFRTVLR-----DHHVET
Mb2707c|M.bovis_AF2122/97 -------------DGGGLETAEFGMDGLADDPAFHSVLR-----NHHVET
Rv2688c|M.tuberculosis_H37Rv -------------DGGGLETAEFGMDGLADDPAFHSVLR-----NHHVET
MAB_1858|M.abscessus_ATCC_1997 -------------AAGELAGQDFPLDGLADNDAFHAVLR-----GHHVET
MMAR_2026|M.marinum_M -------------NGGGLSAAEFSLDTLADDPAFHAVLR-----EHQVET
TH_2745|M.thermoresistible__bu -----IDALRTAPYIHEFSTDDGLHTFSVDRTDLDRTMT--ELTTLGIEE
: * : .
MAV_3321|M.avium_104 MRVEQRSLEDVFLDLTGRKLRQ
MUL_1859|M.ulcerans_Agy99 MRVEQRSLEDVFLDLTGRKLRS
MLBr_00590|M.leprae_Br4923 MRVEQHSLEDVFLDLTGRKLR-
Mflv_3680|M.gilvum_PYR-GCK MRVEQRSLEDVFLDLTGRELRK
MSMEG_1502|M.smegmatis_MC2_155 IHSREASLDDVFVEVTGRQLA-
Mvan_0776|M.vanbaalenii_PYR-1 IHSREASLDEVFVDVTGRSLA-
Mb2707c|M.bovis_AF2122/97 IHSREASLDDVFVEVTGRQLT-
Rv2688c|M.tuberculosis_H37Rv IHSREASLDDVFVEVTGRQLT-
MAB_1858|M.abscessus_ATCC_1997 IHSEEASLDDVFVAVTGRRLA-
MMAR_2026|M.marinum_M IHSREASLEDVFVEVTGRRLS-
TH_2745|M.thermoresistible__bu LTVTPASLEDLFLREYQEVPR-
: **:::*: .