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M. marinum M MMAR_1485 (plcB_2)

annotation: membrane-associated phospholipase C 2 PlcB_2
coordinates: 1798962 - 1800548
length: 528 

MNKLGGMSRRKFLAKAAAGGAGALMSFAGPVIEKAYGAGPCSGHLSDIEHFVFFLMENRSFDHYFGTLSA
TDGFDSGSPLFQQKGWNPQTQTIDPAGITMPYRFDTTRGPFVDGECLSDPDHSWEAMHKSWNGGANDNWL
PAQVGHSPVPNGGNVPVTMGYLTRKDIPIHYLLADTFTVCDRYFSSVLGPTLPNRLYWLSASLGADGTQG
GPQLTSPPTDPIGRFSWTTMPENLSAAGISWKLYRNKTLGPVLNQYFNYTYDDIVMFFKQAQDPRSELAR
FGMAPTYPFEFMADVKANRLPQVSWVVPNTPQSEHPAFPPAVGAVAIVNLLRILLSNPAVWEKTALIVGY
DENGGFFDHVVPPTAPEGTPGEYLTVPDINSVSGAGGIRGPIGLGYRVPGIVISPFSRGGLMVHDVFDHT
SQLKLISKRFSVPVPNLTPWRDSTVGDMTSAFNFAVPPNPSRPSLSHPGLAALPKLPQCIPNVWLGTVGV
NPNPYTGSPQGIPYRVPFPQSLPSQETTPARGIPSGPC

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1485plcB_2-100% (528)membrane-associated phospholipase C 2 PlcB_2
M. marinum MMMAR_3657plcB_40.068.94% (528) membrane-associated phospholipase C 2 PlcB_4
M. marinum MMMAR_3823plcB_10.069.22% (523) membrane-associated phospholipase C 2 PlcB_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1784cplcD0.071.24% (525) phospholipase C 4 PLCD
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2350cplcB0.069.90% (525) membrane-associated phospholipase C
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0555-7e-9238.18% (516) non-hemolytic phospholipase C
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2799plcB0.067.43% (525) membrane-associated phospholipase C 2 PlcB
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1485|M.marinum_M               --MNKLGGMSRRKFLAKAAAGG-AGALMSFAGPVIEKAYG-AGPCSGHLS
Mb1784c|M.bovis_AF2122/97           MSQSHIGGVSRREFLAKVAAGG-AGALMSFAGPVIEKAYG-AGPCSGHLT
Rv2350c|M.tuberculosis_H37Rv        --------MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYG-AGPCPGHLT
MUL_2799|M.ulcerans_Agy99           --------MSRREFMAKLAAASSAGAMMSLAGPVIEKAYG-AGPCSGHLT
MAB_0555|M.abscessus_ATCC_1997      -----MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLR
                                            ::**.:::. *.    .* :*:  . :::. . ..* .* * 

MMAR_1485|M.marinum_M               DIEHFVFFLMENRSFDHYFGTLSATDGFD--SGSPLFQQKGWNPQTQTID
Mb1784c|M.bovis_AF2122/97           DIEHFVFFMQENRSFDHYFGTLSGTDGFN--TVSPLFQQKGWNPMTQALD
Rv2350c|M.tuberculosis_H37Rv        DIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVD
MUL_2799|M.ulcerans_Agy99           DIEHFVFMLQENRSFDHYFGSLSGINGFD--TPSSAFQQKGWNPQTQSID
MAB_0555|M.abscessus_ATCC_1997      DVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVTLSTGKSVFHQPDPQN
                                    *:**.*.:: **********:**   **:  :       ..    .:. :

MMAR_1485|M.marinum_M               PAGITMPYRFDTTRGPFVDGECLSDPDHSWEAMHKSWNGGANDNWLPAQV
Mb1784c|M.bovis_AF2122/97           ATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQA
Rv2350c|M.tuberculosis_H37Rv        PAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQV
MUL_2799|M.ulcerans_Agy99           PAGVTIPYRFDTTRGPLLNGACANDPGHQWIDMHRAFNNGANDNWLGAQA
MAB_0555|M.abscessus_ATCC_1997      PDGYLLPFHLDTAVNSVQK---IPTTSHAWSVQHDSWNHGKMDNWMAAHR
                                    . *  :*:::**: ...        ..* *   * ::* *  ***: *: 

MMAR_1485|M.marinum_M               GHSPVPNGGNVPVTMGYLTRKDIPIHYLLADTFTVCDRYFSSVLGPTLPN
Mb1784c|M.bovis_AF2122/97           KTR---SAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPN
Rv2350c|M.tuberculosis_H37Rv        PFSP--LQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPN
MUL_2799|M.ulcerans_Agy99           QAQT--LQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHCSLIGGTSPN
MAB_0555|M.abscessus_ATCC_1997      KADG----EHYPYVMGYYERADIPFHFALAEAFTVCDNFHSSVMGPTWPN
                                             : * .**:  * * *:*: **::**:** :..*::* * **

MMAR_1485|M.marinum_M               RLYWLSASLGADGTQGGPQLTSPPTDPIGRFSWTTMPENLSAAGISWKLY
Mb1784c|M.bovis_AF2122/97           RLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVY
Rv2350c|M.tuberculosis_H37Rv        RLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVY
MUL_2799|M.ulcerans_Agy99           RLYWMSAWVDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVY
MAB_0555|M.abscessus_ATCC_1997      RMMWMTGTIDPDAAHGGPIIRNTPVS--GGYGWTTYAERLEAAGVSWRVY
                                    *: *::. :..:. .*** : ..  .    :.*   .:.*. **:**::*

MMAR_1485|M.marinum_M               RNKTLGPVLNQYFNYTYDDIVMFFKQAQDPRSELARFGMAPTYPFEFMAD
Mb1784c|M.bovis_AF2122/97           RNKTLGPISS---VLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAAD
Rv2350c|M.tuberculosis_H37Rv        QNKLLGALNN--TVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAAD
MUL_2799|M.ulcerans_Agy99           QNKLLGALNN--TVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVAD
MAB_0555|M.abscessus_ATCC_1997      AEEDDYGGCN------VLKLFSRFQRSR-PGEPLYDKGIAPVRATQFEDD
                                     ::      .         :.  * ::  * . :   *::*  . .*  *

MMAR_1485|M.marinum_M               VKANRLPQVSWVVPNTPQSEHPAFPPA--VGAVAIVNLLRILLSNPAVWE
Mb1784c|M.bovis_AF2122/97           VLANRLPRVSWVIPNVLESEHPAVPAA--AGAFAIVNILRILLANPAVWE
Rv2350c|M.tuberculosis_H37Rv        VRNNRLPKVSWVLPGFLLSEHPAFPVN--VGAVAIVDALRILLSNPAVWE
MUL_2799|M.ulcerans_Agy99           VASNRLPQVSWVLPGFQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWE
MAB_0555|M.abscessus_ATCC_1997      ARAGRLPAVSWLIMTSTASEHPDYRPA--DGAAYIASKIDAIAANPEVWA
                                    .  .*** ***::     ****        *.  *.. :  : :** ** 

MMAR_1485|M.marinum_M               KTALIVGYDENGGFFDHVVPPTAPEGTPGEYLTVPDINSVSGAGGIRGPI
Mb1784c|M.bovis_AF2122/97           KTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPI
Rv2350c|M.tuberculosis_H37Rv        KTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPI
MUL_2799|M.ulcerans_Agy99           KTALIVSFDENGGFFDHVTPTTAPEGTPGEWITVPDINAVTGSGGIRGPI
MAB_0555|M.abscessus_ATCC_1997      KTVFILNYDENDGLFDHVVPPTPPPGTPGEWVKG-------------VPI
                                    **.:*:.:***.*:****.*.*.* *****::.               **

MMAR_1485|M.marinum_M               GLGYRVPGIVISPFSRGGLMVHDVFDHTSQLKLISKRFSVPVPNLTPWRD
Mb1784c|M.bovis_AF2122/97           GLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRR
Rv2350c|M.tuberculosis_H37Rv        GLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRD
MUL_2799|M.ulcerans_Agy99           GLGYRVPCFVISPYSRGPLMVHDIFDHTSQLRLLEQRFGVPVPNLTTWRR
MAB_0555|M.abscessus_ATCC_1997      GGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRR
                                    * *:*** :****:* *  :. : ***** *:::    .*  **:: ** 

MMAR_1485|M.marinum_M               STVGDMTSAFNFAVPPNPSRPSLSHPGLAALPKLPQCIPNVWLGTVGVNP
Mb1784c|M.bovis_AF2122/97           SVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINR--
Rv2350c|M.tuberculosis_H37Rv        ATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKT-
MUL_2799|M.ulcerans_Agy99           GVTGDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVT-VFTKT-
MAB_0555|M.abscessus_ATCC_1997      KTFGNLLSAFGFDSPVRPAPELPDTAAVVAAADRTDTRP-----------
                                     . *:: *:*.*  * ..:    . . : * .   :  *           

MMAR_1485|M.marinum_M               NPYTGSPQGIPYRVPFPQSLPSQE-TTPARGIPSGPC
Mb1784c|M.bovis_AF2122/97           --------GIPYRVPDPQIMPTQE-TTPTRGIPSGPC
Rv2350c|M.tuberculosis_H37Rv        --------AIPYRVPFPQSMPTQE-TAPTRGIPSGLC
MUL_2799|M.ulcerans_Agy99           --------VPPYRVPFPQVMPSQE-TSPTRGIPSGPC
MAB_0555|M.abscessus_ATCC_1997      ---------PPVIPPAPQTSPVQEPGSRPRRYPRR--
                                              *   * **  * **  : .*  *