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MQMIASWPPRMDLKDVAAWAQRVERLGFDVIHVPETIHDAFTVATLALTHTQRIIVRTSMIVAFPRSPML TAYAAWDLAKYSDGRFELGIASQVRGNIVGRFSTEWSDPVSRLGDYVNSLRAIFDSFQTGAPLHHSGPHY RFERLQPYFNPGPIAHRAPRIWTGGVNRRMCNLAGELSDGFVCHPTNSHPRVLRASTLPALAQGAATAQR ADGGPAVVTNPQPMMAATHDGVERLREPRRAELAFLYSTPAYRRQLEYFGLEDVGLALSEMAHRADWTDL AGHLTDEVMDLVVPQGSYPEIPDILAEWYSGVCSGISLSVPGDAEDDASLAELVGRCKHIEPAAALAPPE VDESAESRPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2980 | - | - | 100% (360) | hypothetical protein MMAR_2980 |
| M. marinum M | MMAR_1372 | - | 2e-38 | 31.87% (320) | hypothetical protein MMAR_1372 |
| M. marinum M | MMAR_1390 | - | 1e-35 | 30.72% (306) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1395 | - | 9e-41 | 34.58% (295) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4326 | - | 3e-41 | 35.48% (279) | putative oxidoreductase |
| M. tuberculosis H37Rv | Rv1360 | - | 9e-41 | 34.58% (295) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 1e-07 | 28.80% (191) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3914c | - | 7e-43 | 36.30% (281) | oxidoreductase |
| M. avium 104 | MAV_2121 | - | 6e-41 | 30.49% (328) | hypothetical protein MAV_2121 |
| M. smegmatis MC2 155 | MSMEG_2256 | - | 1e-43 | 34.49% (316) | hypothetical protein MSMEG_2256 |
| M. thermoresistible (build 8) | TH_1626 | - | 3e-43 | 33.76% (314) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2504 | - | 1e-37 | 31.56% (320) | hypothetical protein MUL_2504 |
| M. vanbaalenii PYR-1 | Mvan_2020 | - | 3e-43 | 32.61% (322) | putative oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2121|M.avium_104 ----------MHVDAMTVPQPLGQIGDLARRTQSAGFSGLLFTETG-RTA
MUL_2504|M.ulcerans_Agy99 ----------MHIDVMTIPQPLAQIGDLARRTQAAGLSGLLFTETG-RTA
MMAR_2980|M.marinum_M ---------MQMIASWPPRMDLKDVAAWAQRVERLGFDVIHVPETI-HDA
MSMEG_2256|M.smegmatis_MC2_155 ---MTDAQNPGVKVDRGISSRLSDVAQTARDLETAGCDGCWTGEIN-HDP
TH_1626|M.thermoresistible__bu ---MGGGAVSGLKIDRGIPSQLDRVPDVARTLERQGYDGCWTGEIN-HDP
Mflv_4326|M.gilvum_PYR-GCK -------------MDAAVVSQLSHVPAAARTLEQRGYDGCWTAEIN-HDP
Mvan_2020|M.vanbaalenii_PYR-1 ---MGAGG--GLKVDAAVVSQLSQVPAAARRLERRGYDGCWTAEIN-HDP
Mb1395|M.bovis_AF2122/97 ---MGGAR--RLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
Rv1360|M.tuberculosis_H37Rv ---MGGAR--RLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
MAB_3914c|M.abscessus_ATCC_199 -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
. : * * .
MAV_2121|M.avium_104 YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAVAWELQEATKGRFRLGL
MUL_2504|M.ulcerans_Agy99 YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MMAR_2980|M.marinum_M FTVATLALTHTQRIIVRTSMIVAFPRSPMLTAYAAWDLAKYSDGRFELGI
MSMEG_2256|M.smegmatis_MC2_155 FLPLALAAEHTRRIQIGTSIAVAFARNPMTVAHLGWDLQAYSGGRFILGL
TH_1626|M.thermoresistible__bu FLPLLLAAEHTTRLEIGTSIAVAFARNPMTVANIGWDLQAYSRGRFVLGL
Mflv_4326|M.gilvum_PYR-GCK FLPLTLAAEHTERMELGTSIAVAFARNPMSVAQIGWDLQDYSEGRLLLGL
Mvan_2020|M.vanbaalenii_PYR-1 FLPLTLAAEHTHSIELGTSIAVAFARNPMTVAQIGWDLQDYSGGRFILGL
Mb1395|M.bovis_AF2122/97 FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
Rv1360|M.tuberculosis_H37Rv FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
MAB_3914c|M.abscessus_ATCC_199 FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MLBr_00348|M.leprae_Br4923 YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
: : : : *.: .*.* * . * : *: **:
MAV_2121|M.avium_104 GTQVRTHVVRRYGAAFERPGPRLRDYLLAVKACFAAFRSGT-LEHHGDFY
MUL_2504|M.ulcerans_Agy99 GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTGT-LDHHGEFY
MMAR_2980|M.marinum_M ASQVRGNIVGRFSTEWSDPVSRLGDYVNSLRAIFDSFQTGAPLHHSGPHY
MSMEG_2256|M.smegmatis_MC2_155 GTQIRPHIEKRFSMPWSHPVRRMREYIAALQAIWTCWRDGTSLRFEGEFY
TH_1626|M.thermoresistible__bu GTQIRPHVERRFSMPWSHPVRRMREFVTALREIWSCWRDGTRLSFHGDFY
Mflv_4326|M.gilvum_PYR-GCK GSQIKPHIEKRFSMPWGRPVARMREFVQALHEIWACWRDGTRLNFEGEFY
Mvan_2020|M.vanbaalenii_PYR-1 GSQIKPHIEKRFSMPWSKPVGRMREFVLALRAIWMSWSDGSRLEFDGEFY
Mb1395|M.bovis_AF2122/97 GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFY
Rv1360|M.tuberculosis_H37Rv GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFY
MAB_3914c|M.abscessus_ATCC_199 GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQERGALDYRGDFY
MLBr_00348|M.leprae_Br4923 GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAR---EAPVVSDGQHY
. . : :. : * * : : :: : : * .*
MAV_2121|M.avium_104 DLDFITPQWS-----PGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVH
MUL_2504|M.ulcerans_Agy99 DLDLITPQWS-----AGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVH
MMAR_2980|M.marinum_M RFERLQPYFN-----PGP---IAHRAPRIWTGGVNRRMCNLAGELSDGFV
MSMEG_2256|M.smegmatis_MC2_155 THKIMTPMFT-----PEP---SPAPFPKVFVAAVGERMTEMCGEAADGLL
TH_1626|M.thermoresistible__bu SHTLMTPMFV-----PEP---QPHGDPRIFLAAVGPEMTRMCGEVADGLL
Mflv_4326|M.gilvum_PYR-GCK THTLMTPMFV-----PQQ---HAYADPKVFVAAVGDRMTEMCGEVADGLL
Mvan_2020|M.vanbaalenii_PYR-1 THKLMTPMFV-----PPR---HPYGDPRVFVAAVGDRMTEMCGEVADGLL
Mb1395|M.bovis_AF2122/97 THKIMTPMFT-----PEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHL
Rv1360|M.tuberculosis_H37Rv THKIMTPMFT-----PEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHL
MAB_3914c|M.abscessus_ATCC_199 QNTLMTPMFM-----PDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFM
MLBr_00348|M.leprae_Br4923 PLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
. : .. . :..* .**
MAV_2121|M.avium_104 VHPIG-EPGYLARHVLPTVAEGAAKAG--RSPSDIAIIVPVMTIVGDSDE
MUL_2504|M.ulcerans_Agy99 IHPLG-ELGYLTRHVVPNVAKGAAKAG--RSPADIAVILPVMTIVGDSDE
MMAR_2980|M.marinum_M CHPTNSHPRVLRASTLPALAQGAATAQ--RADGGPAVVTNPQPMMAATHD
MSMEG_2256|M.smegmatis_MC2_155 AHAFT-TRRYLDEVTLPALQRGMDRTG--RSRNDFEVSCPVFLVTGSDEH
TH_1626|M.thermoresistible__bu AHAFT-TRRYLDEVTLPALLDGMNRAG--RRRGDFEVSCPVFVVTGTTET
Mflv_4326|M.gilvum_PYR-GCK AHAFS-TQRYVREVTIPTLERGIARAG--RTRADVVVSSPLFVVTGHDEQ
Mvan_2020|M.vanbaalenii_PYR-1 AHAFS-TQRYVREVTIPTLTRGIERAG--RTRADIEVASPLFIVTGLDEQ
Mb1395|M.bovis_AF2122/97 GHPMV-SKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDA
Rv1360|M.tuberculosis_H37Rv GHPMV-SKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDA
MAB_3914c|M.abscessus_ATCC_199 SHPFC-TPDYLAQVTRPALGRGALKSG--KALADIQIHHSPMIIIGRDDA
MLBr_00348|M.leprae_Br4923 PIFFS---PRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDR-
: : * : : :
MAV_2121|M.avium_104 ERDQQREAVRASMAFYGS------TPNYAFIWDEAGFEGTTARIREKQKA
MUL_2504|M.ulcerans_Agy99 ERAIERESVRASMAFYGS------TPNYAFIWDEAGFEGTTARIREKQKA
MMAR_2980|M.marinum_M GVERLREPRRAELAFLYS------TPAYRRQLEYFGLEDVGLALSEMAHR
MSMEG_2256|M.smegmatis_MC2_155 QMAEAAVATRKQLAFYGS------TPAYRKVLELHGWGDLHTELHRLSLA
TH_1626|M.thermoresistible__bu ELRANAVATRRQLAFYAS------TPAYRSVLDLHGWGDLHTELHALSRR
Mflv_4326|M.gilvum_PYR-GCK ELAANAVATRKQIAFYAS------TPAYRGVLELHGWGDLQTELHRLSRA
Mvan_2020|M.vanbaalenii_PYR-1 QMAAAAVATRKQIAFYAS------TPAYRSVLELHGWGDLQTELHSLSRE
Mb1395|M.bovis_AF2122/97 ELAAACTATRKQIAFYGS------TPAYRKVLEQHGWGDLHPELHRLSKL
Rv1360|M.tuberculosis_H37Rv ELAAACTATRKQIAFYGS------TPAYRKVLEQHGWGDLHPELHRLSKL
MAB_3914c|M.abscessus_ATCC_199 ELASARAAVRKQLAFYGS------TPAYWPILELHGRAEMGPELKERSKQ
MLBr_00348|M.leprae_Br4923 --AAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRS
: :*: . * : * :
MAV_2121|M.avium_104 GDYAGMAAQVSDDHIAVFATEST-WDGLADALIEKYSGTATRLVMYNSAA
MUL_2504|M.ulcerans_Agy99 GDFPAMMAQISDEHIDAFATESS-WDGLADALTDKYGGIATRLVMYNALG
MMAR_2980|M.marinum_M ADWTDLAGHLTDEVMDLVVPQGS-YPEIPDILAEWYSGVCSGISLS-VPG
MSMEG_2256|M.smegmatis_MC2_155 GEWDTMGTLIDDDVLDAFAVVAP-LDELADALRRRCEGAIDRVLPGFPAA
TH_1626|M.thermoresistible__bu GEWDAMGERIDDDVLAAFAVVAP-LDELAGRLRERCAGVIDRVLPAFPAG
Mflv_4326|M.gilvum_PYR-GCK GEWDTMGALIDDTMLAEFAVVAP-VDELVHTIRARCDGLIDRVLVGFPPS
Mvan_2020|M.vanbaalenii_PYR-1 GDWDTMGSLIDDGMLAEFAVVAL-VDDVVDKIRARCDGLIDRVLVGFPPS
Mb1395|M.bovis_AF2122/97 GEWEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAA
Rv1360|M.tuberculosis_H37Rv GEWEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAA
MAB_3914c|M.abscessus_ATCC_199 GEWEAMAALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYR
MLBr_00348|M.leprae_Br4923 NQKDKAAEIIPNELVDSTMIVGD-VDYVCKQIAAWSAAGVTMMMVSASSV
: : : : : :
MAV_2121|M.avium_104 DPERFERYGEVARRIQHAVSG-----------------
MUL_2504|M.ulcerans_Agy99 DPGRFERYGEVARRMHG---------------------
MMAR_2980|M.marinum_M DAEDDASLAELVGRCKHIEPAAALAPPEVDESAESRPI
MSMEG_2256|M.smegmatis_MC2_155 VPPATVNAVLDEFRDRP-----PVTRL-----------
TH_1626|M.thermoresistible__bu VPETAVTAVLHELRAAPSPTTSPVSTERSRHP------
Mflv_4326|M.gilvum_PYR-GCK IDEATVVGLVSELQAEETS-------------------
Mvan_2020|M.vanbaalenii_PYR-1 IDEATVVDLVTDLRTGA---------------------
Mb1395|M.bovis_AF2122/97 S-QECINAALQDFRR-----------------------
Rv1360|M.tuberculosis_H37Rv S-QECINAALQDFRR-----------------------
MAB_3914c|M.abscessus_ATCC_199 PDRALLPELLAAFPTR----------------------
MLBr_00348|M.leprae_Br4923 EQVRDLAGLF----------------------------