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M. marinum M MMAR_0965 (gloB)

annotation: glyoxalase II, GloB
coordinates: 1179962 - 1180678
length: 238

SDSDRLYFRQLLAGRDFAVNDMIAAQMRNFAYLIGDRETGDCVVVDPAYAAGDLVNALEADDMHLSGVLV
THHHPDHVGGSMMGFELKGLAELLERVSVPVHVNTHEAVWVSRVTGIPMSDLTTHEHRDKVSVGDIEIEL
LHTPGHTPGSQCFLLDGRLVAGDTLFLEGCGRTDFPGGDSDEIFRSLQQLAALPGDPTVFPGHWYSAEPS
ASLSEVKRSNFVYRAADLAQWRMLMGG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0965gloB-100% (238)glyoxalase II, GloB
M. marinum MMMAR_2126-8e-1527.80% (205) Zn-dependent glyoxylase
M. marinum MMMAR_3351-1e-1432.97% (182) hypothetical protein MMAR_3351

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0651c-1e-12488.89% (234) glyoxalase II
M. gilvum PYR-GCKMflv_5123-1e-12084.87% (238) beta-lactamase domain-containing protein
M. tuberculosis H37RvRv0634c-1e-12488.89% (234) glyoxalase II
M. leprae Br4923MLBr_01912-1e-12186.02% (236) putative glyoxylase II
M. abscessus ATCC 19977MAB_4755c-1e-1431.32% (182) hypothetical protein MAB_4755c
M. avium 104MAV_4532-1e-12186.55% (238) metallo-beta-lactamase family protein
M. smegmatis MC2 155MSMEG_1334-1e-10979.57% (235) metallo-beta-lactamase family protein
M. thermoresistible (build 8)TH_1873-1e-11883.12% (237) POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX
M. ulcerans Agy99MUL_0715gloB1e-13898.74% (238) glyoxalase II, GloB
M. vanbaalenii PYR-1Mvan_1228-1e-11984.03% (238) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5123|M.gilvum_PYR-GCK          ------------------------MADTDRLYFRQLLSGRDFAAGDMIAQ
Mvan_1228|M.vanbaalenii_PYR-1       MRPFDRQKDPCARIRRPPLHTLTGMADSDRLYFRQLLSGRDYAAGDMIAQ
MSMEG_1334|M.smegmatis_MC2_155      -----------------MAERTSDPAANDRFYFRQLLSGRDFAGADPIAQ
TH_1873|M.thermoresistible__bu      ---------------------VSD---SDRLYFRQLLSGRDFAAGDMMAQ
Mb0651c|M.bovis_AF2122/97           ------------------------MSK-DRLYFRQLLSGRDFAVGDMFAT
Rv0634c|M.tuberculosis_H37Rv        ------------------------MSK-DRLYFRQLLSGRDFAVGDMFAT
MAV_4532|M.avium_104                ------------------------MSD-DRLYFRQLLSGRDFAAGDMFAT
MMAR_0965|M.marinum_M               ------------------------MSDSDRLYFRQLLAGRDFAVNDMIAA
MUL_0715|M.ulcerans_Agy99           ------------------------MSDSDRLYFRQLLSGRDFAVNDMIAA
MLBr_01912|M.leprae_Br4923          ------------------------MSDSDRLYFRQLLSGRDFAVDDVVAT
MAB_4755c|M.abscessus_ATCC_199      ------------------------------MSGIERVITRGTFELDGGSW
                                                                  :   : :  *.    *  : 

Mflv_5123|M.gilvum_PYR-GCK          QMRNFAYLIGDRETGDAVVVDPAYAAGELVDALEADGMHLSGVLVTHHHP
Mvan_1228|M.vanbaalenii_PYR-1       QMRNFAYLIGDRETGDTVVVDPAYAAQDLVDALEADGMQLSGVLVTHHHP
MSMEG_1334|M.smegmatis_MC2_155      QMRNFAYFIGDRETGEAVVVDPAYAADELAAALEADGMRLAGVLVTHHHP
TH_1873|M.thermoresistible__bu      QMRNFAYLIGDRETGECVVVDPAYAANDLVDAAEADGMRLTGVLVSHHHP
Mb0651c|M.bovis_AF2122/97           QMRNFAYLIGDRTTGDCVVVDPAYAAGDLLDALESDDMQLSGVLVTHHHP
Rv0634c|M.tuberculosis_H37Rv        QMRNFAYLIGDRTTGDCVVVDPAYAAGDLLDALESDDMQLSGVLVTHHHP
MAV_4532|M.avium_104                QMRNFAYLIGDRQTGDCVVVDPAYAASDLLDTLEADGMHLSGVLVTHHHP
MMAR_0965|M.marinum_M               QMRNFAYLIGDRETGDCVVVDPAYAAGDLVNALEADDMHLSGVLVTHHHP
MUL_0715|M.ulcerans_Agy99           QMRNFAYLIGDRETGDCVVVDPAYAAGDLVNALEAGDMHLSGVLVTHHHP
MLBr_01912|M.leprae_Br4923          QMRNFAYLIGDRQTGDCVVVDPAYAAGDLVDALEADGMRLSGVLVTHHHP
MAB_4755c|M.abscessus_ATCC_199      EVDNNIWIVG--EGDDVVVFDAAHSAQPIIDAVG--GRNVVAVVCTHGHN
                                    :: *  :::*    .: **.*.*::*  :  :    . .: .*: :* * 

Mflv_5123|M.gilvum_PYR-GCK          DHVGGSMMGFTLKGLAELLERVSVPVHVNAHEADWVSKVTGIAPSELTTH
Mvan_1228|M.vanbaalenii_PYR-1       DHIGGSMMGFELKGLAELLERVSVPIHVNAHEADWVSRTTGIARSELTAH
MSMEG_1334|M.smegmatis_MC2_155      DHVGGSMMGFTLKGVAELLEHRSVPVHVNSHEADWVSQVTGIARSELSAH
TH_1873|M.thermoresistible__bu      DHVGGSMMGFTLKGVAELLERAEVPVHVNTHEADWVSRVTGIPLSDLTAH
Mb0651c|M.bovis_AF2122/97           DHVGGSMMGFQLPGLAELLERASVPVHVNTHEALWVSRVTGIPVGDLITH
Rv0634c|M.tuberculosis_H37Rv        DHVGGSMMGFQLPGLAELLERASVPVHVNTHEALWVSRVTGIPVGDLITH
MAV_4532|M.avium_104                DHVGGSMMGFTLAGLAELVERAPVPVHVNSHEALWVSRVTGISASDLTAH
MMAR_0965|M.marinum_M               DHVGGSMMGFELKGLAELLERVSVPVHVNTHEAVWVSRVTGIPMSDLTTH
MUL_0715|M.ulcerans_Agy99           DHVGGSMMGFELKGLAELLERVSVPVHVNTHEAVWVSRVTGIPMSDLTTH
MLBr_01912|M.leprae_Br4923          DHVGGVMMGFQLKGLTELLERVTVPVHVNTHEALWISRVTGIDIGHLTTH
MAB_4755c|M.abscessus_ATCC_199      DHIT---------VAPELSQALDAPVLL--HPADDVLWRMTHPDKDFRAV
                                    **:            .** :   .*: :  * *  :         .: : 

Mflv_5123|M.gilvum_PYR-GCK          QHGDTVSIGDIDIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
Mvan_1228|M.vanbaalenii_PYR-1       QHGDKVSVGDIDIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
MSMEG_1334|M.smegmatis_MC2_155      EHGDTISVGAIDIELLHTPGHTPGSQCFLVDGR--LVAGDTLFLEGCGRT
TH_1873|M.thermoresistible__bu      DHGDKVTVGAVEIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
Mb0651c|M.bovis_AF2122/97           EHGDKVSVGDIDIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
Rv0634c|M.tuberculosis_H37Rv        EHGDKVSVGDIDIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
MAV_4532|M.avium_104                ENHDKVSIGDIEIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
MMAR_0965|M.marinum_M               EHRDKVSVGDIEIELLHTPGHTPGSQCFLLDGR--LVAGDTLFLEGCGRT
MUL_0715|M.ulcerans_Agy99           EHRDKVSVGDIEIELLHTPGHTPGSQCFLLDGQ--LVAGDTLFLEGCGRT
MLBr_01912|M.leprae_Br4923          EHRDKLSVGDIEIELLHTPGHTPGSQCFLLDGL--LVAGDTLFLEGCGRT
MAB_4755c|M.abscessus_ATCC_199      EDDMVLPVGGLELHALHTPGHSPGSVCWYAPELRAVFSGDTLFQGGPGAT
                                    :.   :.:* :::. ******:*** *:       :.:*****  * * *

Mflv_5123|M.gilvum_PYR-GCK          DFPGGDVDDMFRSLQ-ALAQLPGDPTVFPGHWYSAEPSAPLSDVRGSNYV
Mvan_1228|M.vanbaalenii_PYR-1       DFPGGNVDDMFRSLQ-ALAALPGDPTVFPGHWYSADPSAPLSDVRQTNYV
MSMEG_1334|M.smegmatis_MC2_155      DFPGGNVDDMFRSLQ-ALAKLPGDPTVYPGHWYSAEPSAPLEEVKRSNYV
TH_1873|M.thermoresistible__bu      DFPGGNVDDMFHSLQ-ALAKLPGDPTVYPGHWYAAEPSASLSEVRRTNYV
Mb0651c|M.bovis_AF2122/97           DFPGGDSDEMYRSLR-QLAELPGDPTVFPGHWYSAEPSASLSEVKRSNYV
Rv0634c|M.tuberculosis_H37Rv        DFPGGDSDEMYRSLR-QLAELPGDPTVFPGHWYSAEPSASLSEVKRSNYV
MAV_4532|M.avium_104                DFPGGDSDEMYRSLQ-RLAKLPGDPTVFPGHWYSAEPSASLSEVKRSNYV
MMAR_0965|M.marinum_M               DFPGGDSDEIFRSLQ-QLAALPGDPTVFPGHWYSAEPSASLSEVKRSNFV
MUL_0715|M.ulcerans_Agy99           DFPGGDSDEIFRSLQ-QLAALPGDPTVFPGHWYSAEPSASLSEVKRSNFV
MLBr_01912|M.leprae_Br4923          DFPGGNSDEMYRSLQ-QLAQLPGNPTVFPGHWYSTAPSATLSMVKCSNYV
MAB_4755c|M.abscessus_ATCC_199      GRSFSDFPTILRSISGRLGPLPEDTVVYTGHGDTTTIGD--EIVHYDDWV
                                    . . .:   : :*:   *. ** :..*:.**  ::  .   . *:  ::*

Mflv_5123|M.gilvum_PYR-GCK          YRASNLDQWRMLMGG
Mvan_1228|M.vanbaalenii_PYR-1       YRASDLDQWRMLMGG
MSMEG_1334|M.smegmatis_MC2_155      YRASNLDQWRMLMGG
TH_1873|M.thermoresistible__bu      YRASNLEQWRMLMGA
Mb0651c|M.bovis_AF2122/97           YRPASLDQWRMLMGG
Rv0634c|M.tuberculosis_H37Rv        YRPASLDQWRMLMGG
MAV_4532|M.avium_104                YRASDLDQWRMLMGG
MMAR_0965|M.marinum_M               YRAADLAQWRMLMGG
MUL_0715|M.ulcerans_Agy99           YRAADLAQWRMLMGG
MLBr_01912|M.leprae_Br4923          YRAADLNQWRMLMDS
MAB_4755c|M.abscessus_ATCC_199      ARGH-----------
                                     *