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M. marinum M MMAR_0879 (fabH)

annotation: 3-oxoacyl-
coordinates: 1069975 - 1070982
length: 335

TEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDEWIYSRTGIKTRRFAAPEESAASMAIEASRE
AIAKAALTGSDIDGVIVATSTHFLQTPACAPIVAAALGCQNVPAFDISAGCSGFGHALGIAADMIRGGSA
ATILVIGTEKLSPTVDMTDRSNCFIFADGAASVLVGHSPIQGIGPTVWGSDGEQAAAIRQDIDWISHAEN
PAGPRPFLRMEGTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRINELLTKNLQLRPDAVIA
NDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIGYGAGLSYAAQVVRMPNS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0879fabH-100% (335)3-oxoacyl-
M. marinum MMMAR_3221fabH_13e-3431.48% (324) 3-oxoacyl-
M. marinum MMMAR_3474-1e-1525.15% (334) ketoacyl-acyl carrier protein synthase III

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0547cfabH1e-15780.78% (333) 3-oxoacyl-(acyl carrier protein) synthase III
M. gilvum PYR-GCKMflv_2540-3e-1624.39% (328) Beta-ketoacyl-acyl-carrier-protein synthase I
M. tuberculosis H37RvRv0533cfabH1e-15780.78% (333) 3-oxoacyl-(acyl carrier protein) synthase III
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1141c-1e-14876.12% (335) 3-oxoacyl-(acyl carrier protein) synthase III
M. avium 104MAV_4612-1e-15981.08% (333) 3-oxoacyl-(acyl carrier protein) synthase III
M. smegmatis MC2 155MSMEG_3953-6e-1725.46% (326) hypothetical protein MSMEG_3953
M. thermoresistible (build 8)TH_1179-1e-1423.60% (339) conserved hypothetical protein
M. ulcerans Agy99MUL_0632fabH0.099.70% (335) 3-oxoacyl-(acyl carrier protein) synthase III
M. vanbaalenii PYR-1Mvan_1354-4e-1323.81% (336) 3-oxoacyl-(ACP) synthase III

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2540|M.gilvum_PYR-GCK          MAVDSHWLVMEGAGPR-ARYRSRLAGAGRHLPPTHLSTRDLMASTRHNTH
TH_1179|M.thermoresistible__bu      --MRTQWLLTEDAEADGAPFRTRLAGAGRHLPVTRLSTDDLTARTRHRTT
MSMEG_3953|M.smegmatis_MC2_155      --MGPHWLVMDAADEASSPFRTRIAAAGRCLPKTRLTTSELMSETRHNTH
MMAR_0879|M.marinum_M               ---------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDE
MUL_0632|M.ulcerans_Agy99           ---------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDE
MAV_4612|M.avium_104                ---------MKQISATSGPTNIGLLSVGSYRPQRAVTNDELCQNIDSSDE
Mb0547c|M.bovis_AF2122/97           ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
Rv0533c|M.tuberculosis_H37Rv        ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
MAB_1141c|M.abscessus_ATCC_199      ---------MTDIAEITGINKIGLLSLGAYRPERVVTNDEICERIESSDE
Mvan_1354|M.vanbaalenii_PYR-1       -----------------MTTTVSLVDVSVHLPGEPIGADHYAQFAESDDL
                                                           :   .   *   :   .          

Mflv_2540|M.gilvum_PYR-GCK          IDLERLTGIRDRRVSTGDEDSYSLATAAAVDCLDRAGQDAAG-LDVVINC
TH_1179|M.thermoresistible__bu      IDLERLTGIRERRISVGDEDSYSLATAAALDCLHRADRAAES-VEVVINC
MSMEG_3953|M.smegmatis_MC2_155      IDLERLTGIRERRVSLGEDDSYSLATKAALDCLEKADRSADS-VEVVINC
MMAR_0879|M.marinum_M               WIYSR-TGIKTRRFAAPEESAASMAIEASREAIAKAALTGSD-IDGVIVA
MUL_0632|M.ulcerans_Agy99           WIYSR-TGIKTRRFAAPEESAASMAIEASREAIAKAALTGSD-IDGVIVA
MAV_4612|M.avium_104                WIYSR-TGIKTRRFAARDESTASMATEAGREAIAKAGLEASD-IDCVVVA
Mb0547c|M.bovis_AF2122/97           WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIVT
Rv0533c|M.tuberculosis_H37Rv        WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIVT
MAB_1141c|M.abscessus_ATCC_199      WIYTR-TGIKTRRFAADEETAQTLAIEAGRKAIANALLTGAE-IDAVIVA
Mvan_1354|M.vanbaalenii_PYR-1       RDNVMFRAPHLRHHVDPETSAIDMAEQAAQGLIARHGQDAVTGADVLITH
                                           . : *:    :  :  :*  *    : .    .    : ::  

Mflv_2540|M.gilvum_PYR-GCK          SITKFRDGLTQWMEPTMSAAVARAIGAEHAMTFDLSNA-CAGMLTGATVL
TH_1179|M.thermoresistible__bu      SITKFRDGLTQWLEPPMSTAVARAIGADTAMTFDLSNA-CAGMLTGVSIL
MSMEG_3953|M.smegmatis_MC2_155      SITKFHGGLTQYLEPTMSSDVAHAIGARDAMTFDISNA-CAGMLTGVMVL
MMAR_0879|M.marinum_M               TSTHFLQ------TPACAPIVAAALGCQNVPAFDISAG-CSGFGHALGIA
MUL_0632|M.ulcerans_Agy99           TSTHFLQ------TPACAPIVAAALGCQNVPAFDISAG-CSGFGHALGIA
MAV_4612|M.avium_104                TSTHFLQ------TPACGPAVAAALGATGVPAFDISAG-CAGFGYALGVA
Mb0547c|M.bovis_AF2122/97           TNTHFLQ------TPPAAPMVAASLGAKGILGFDLSAG-CAGFGYALGAA
Rv0533c|M.tuberculosis_H37Rv        TNTHFLQ------TPPAAPMVAASLGAKGILGFDLSAG-CAGFGYALGAA
MAB_1141c|M.abscessus_ATCC_199      TSTHYLQ------TPASAPAVATALGAQGVPAFDLSAG-CAGFGYAVGVA
Mvan_1354|M.vanbaalenii_PYR-1       TQLPDMP------FYGAGGGMAHRLGMKPNWVIDLHNGGCAAFLLGLKLA
                                    :                .  :*  :*      :*:  . *:.:  .    

Mflv_2540|M.gilvum_PYR-GCK          NNWIRQGTVQRGLVVSGE----YISQLGQNAARHIRSIMSKELACLTLGD
TH_1179|M.thermoresistible__bu      NNWIRQGVVERGMVVSGE----YISQLTANAAQHIRTIMSKELASLTLGD
MSMEG_3953|M.smegmatis_MC2_155      NTWIRQGLVARGMVVSGE----YISQLGQNAAKHIRTVLSKELASLTLGD
MMAR_0879|M.marinum_M               ADMIRGGSAATILVIGTE----KLSPTVDMTDRSNCFIFADGAASVLVGH
MUL_0632|M.ulcerans_Agy99           ADMIRGGSAATILVIGTE----KLSPTVDMTDRSNCFIFVDGAASVLVGH
MAV_4612|M.avium_104                ADMVRGGTAGKVLVLGSE----KLSPTVDMTDRSNCFIFADGAAGVVVGE
Mb0547c|M.bovis_AF2122/97           ADMIRGGGAATMLVVGTE----KLSPTIDMYDRGNCFIFADGAAAVVVGE
Rv0533c|M.tuberculosis_H37Rv        ADMIRGGGAATMLVVGTE----KLSPTIDMYDRGNCFIFADGAAAVVVGE
MAB_1141c|M.abscessus_ATCC_199      GDMIRGGSASKVLVIGSE----KLSPALDMTDRGNCFIFGDGAGAVVVGE
Mvan_1354|M.vanbaalenii_PYR-1       RNLLASGEGRTALIAVVQNAAGQIFEQPTIRRRAQAAVPGDGAAIGLVTV
                                       :  *     ::   :     :        :    :  .  .   :  

Mflv_2540|M.gilvum_PYR-GCK          AGAALLFERAPADSAAGISLAGFTTVADHSRLCLAYPKG-DDPGARMFTD
TH_1179|M.thermoresistible__bu      AGAALLLERAYPGSGS-IRLSGFTTIADHSRLCLAYPKG-PEPGARMFTD
MSMEG_3953|M.smegmatis_MC2_155      AGAALLLERVPAGGSG-ITLAGFTTIADYSRLCLAYPKG-RDPGARMFTD
MMAR_0879|M.marinum_M               SPIQGIGPTVWGSDGE----QAAAIRQDIDWISHAENP--AGPRPFLRME
MUL_0632|M.ulcerans_Agy99           SPIQGIGPTVWGSDGE----QAAAIRQDIDWISHAENP--AGPRPFLRME
MAV_4612|M.avium_104                TPTQGIGPTVWGSDGT----QATAIRQDIDWMDYLDRP--TGPRPFLRLE
Mb0547c|M.bovis_AF2122/97           TPFQGIGPTVAGSDGE----QADAIRQDIDWITFAQNP--SGPRPFVRLE
Rv0533c|M.tuberculosis_H37Rv        TPFQGIGPTVAGSDGE----QADAIRQDIDWITFAQNP--SGPRPFVRLE
MAB_1141c|M.abscessus_ATCC_199      TAEQGIGPTVWGSDGS----QSNAIRQDIDWMDFAAAPDPEGPRPYLRIE
Mvan_1354|M.vanbaalenii_PYR-1       SDESPILDVECRTYGEYAG--DMTIAVDPPRKWWQAGPG-EGCIGFTESK
                                    :    :        .        :   *                     .

Mflv_2540|M.gilvum_PYR-GCK          SRGIQRAAIAATPYLLHEVLDAAGISIGDIDHVITHQTSARAIRKGMAAL
TH_1179|M.thermoresistible__bu      SRGIQRAAIAATPVLLQEVLDQTGLSIHDIDHVITHQTSARAIRKGMRRI
MSMEG_3953|M.smegmatis_MC2_155      SRAIHRAAITNTPVLLREVLDTAGISIDDIDHVITHQTSARAIKKGMAVM
MMAR_0879|M.marinum_M               GTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRIN----ELL
MUL_0632|M.ulcerans_Agy99           GTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRIN----ELL
MAV_4612|M.avium_104                GSAVFRWAAFEMGKVGQQAMDAAGVRPDEIDVFLPHQANSRIN----EIL
Mb0547c|M.bovis_AF2122/97           GPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELL
Rv0533c|M.tuberculosis_H37Rv        GPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELL
MAB_1141c|M.abscessus_ATCC_199      GTSVFRWAAFEMGKVGQRAMEAAKVGPEQIDVFVPHQANTRIN----ELL
Mvan_1354|M.vanbaalenii_PYR-1       ITKVLARGNRQVPEVSYAVCDRIGLPPKDVDLFVTNQPNRVFLR----NW
                                       :   .      :   . :   :   ::* .:.:*..           

Mflv_2540|M.gilvum_PYR-GCK          TESFGGGPRHDAVITVDRYGNTASTTHTVALVEELEAGRIRAGETIALIA
TH_1179|M.thermoresistible__bu      ADEFGGTPAHDAVITVDKYGNTASTTHTVALVDELEAGGIAPGETIALIA
MSMEG_3953|M.smegmatis_MC2_155      AAEFGDHPRHDAVITVDRYGNTASTTHTVALIEELEARRIEPGETVALIA
MMAR_0879|M.marinum_M               TKNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIG
MUL_0632|M.ulcerans_Agy99           TKNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIG
MAV_4612|M.avium_104                AKSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIG
Mb0547c|M.bovis_AF2122/97           VKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIG
Rv0533c|M.tuberculosis_H37Rv        VKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIG
MAB_1141c|M.abscessus_ATCC_199      AKNLHLRADAVIANDIEHTGNTSAASVPLAMETLLSTGAAKPGDLALLIG
Mvan_1354|M.vanbaalenii_PYR-1       REALELPP-ERHVDTFDECGNLFAAGIPVNLDRAVREGRVKRGDTVLMAA
                                       :   .    .  .:. **  ::  .: :   :       *:   : .

Mflv_2540|M.gilvum_PYR-GCK          LASGLEIGVVLLTLDEELVNRYGHRD
TH_1179|M.thermoresistible__bu      LASGLEIGIVLLTLDEEMVGRHGNRG
MSMEG_3953|M.smegmatis_MC2_155      LASGLEIGIHLADR------------
MMAR_0879|M.marinum_M               YGAGLSYAAQVVRMPNS---------
MUL_0632|M.ulcerans_Agy99           YGAGLSYAAQVVRMPNS---------
MAV_4612|M.avium_104                YGAGLSYAAQVVRLPPG---------
Mb0547c|M.bovis_AF2122/97           YGAGLSYAAQVVRMPKG---------
Rv0533c|M.tuberculosis_H37Rv        YGAGLSYAAQVVRMPKG---------
MAB_1141c|M.abscessus_ATCC_199      YGAGLSYAAQVVRMPPVPFE------
Mvan_1354|M.vanbaalenii_PYR-1       FAHAGDFAAAAALRWGGRD-------
                                     . . . .