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GPHWLVMDAADEASSPFRTRIAAAGRCLPKTRLTTSELMSETRHNTHIDLERLTGIRERRVSLGEDDSYS LATKAALDCLEKADRSADSVEVVINCSITKFHGGLTQYLEPTMSSDVAHAIGARDAMTFDISNACAGMLT GVMVLNTWIRQGLVARGMVVSGEYISQLGQNAAKHIRTVLSKELASLTLGDAGAALLLERVPAGGSGITL AGFTTIADYSRLCLAYPKGRDPGARMFTDSRAIHRAAITNTPVLLREVLDTAGISIDDIDHVITHQTSAR AIKKGMAVMAAEFGDHPRHDAVITVDRYGNTASTTHTVALIEELEARRIEPGETVALIALASGLEIGIHL ADR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3953 | - | - | 100% (354) | hypothetical protein MSMEG_3953 |
| M. smegmatis MC2 155 | MSMEG_3951 | - | 4e-08 | 23.49% (298) | hypothetical protein MSMEG_3951 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0547c | fabH | 2e-16 | 26.32% (342) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. gilvum PYR-GCK | Mflv_2540 | - | 1e-145 | 74.50% (349) | Beta-ketoacyl-acyl-carrier-protein synthase I |
| M. tuberculosis H37Rv | Rv0533c | fabH | 2e-16 | 26.32% (342) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1141c | - | 5e-13 | 23.15% (324) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. marinum M | MMAR_3474 | - | 1e-150 | 76.07% (351) | ketoacyl-acyl carrier protein synthase III |
| M. avium 104 | MAV_4612 | - | 6e-18 | 25.07% (351) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. thermoresistible (build 8) | TH_1179 | - | 1e-145 | 74.64% (351) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0632 | fabH | 9e-17 | 25.46% (326) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4612|M.avium_104 ---------MKQISATSGPTNIGLLSVGSYRPQRAVTNDELCQNIDSSDE
MUL_0632|M.ulcerans_Agy99 ---------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDE
Mb0547c|M.bovis_AF2122/97 ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
Rv0533c|M.tuberculosis_H37Rv ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
MAB_1141c|M.abscessus_ATCC_199 ---------MTDIAEITGINKIGLLSLGAYRPERVVTNDEICERIESSDE
Mflv_2540|M.gilvum_PYR-GCK MAVDSHWLVMEG-AGPRARYRSRLAGAGRHLPPTHLSTRDLMASTRHNTH
MMAR_3474|M.marinum_M --MTRHWLVMETPNGPHAPYVTRIAGAGRHLPETHLTTDELMSSTRHRTH
TH_1179|M.thermoresistible__bu --MRTQWLLTEDAEADGAPFRTRLAGAGRHLPVTRLSTDDLTARTRHRTT
MSMEG_3953|M.smegmatis_MC2_155 --MGPHWLVMDAADEASSPFRTRIAAAGRCLPKTRLTTSELMSETRHNTH
. : . * * ::. ::
MAV_4612|M.avium_104 WIYSR-TGIKTRRFAARDESTASMATEAGREAIAKAGLEASDIDCVVVAT
MUL_0632|M.ulcerans_Agy99 WIYSR-TGIKTRRFAAPEESAASMAIEASREAIAKAALTGSDIDGVIVAT
Mb0547c|M.bovis_AF2122/97 WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTT
Rv0533c|M.tuberculosis_H37Rv WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTT
MAB_1141c|M.abscessus_ATCC_199 WIYTR-TGIKTRRFAADEETAQTLAIEAGRKAIANALLTGAEIDAVIVAT
Mflv_2540|M.gilvum_PYR-GCK IDLERLTGIRDRRVSTGDEDSYSLATAAAVDCLDRAGQDAAGLDVVINCS
MMAR_3474|M.marinum_M IDLERLTGIRERRVSVGDEDSYSLATAAALDALAAARQDPASLDVVINCS
TH_1179|M.thermoresistible__bu IDLERLTGIRERRISVGDEDSYSLATAAALDCLHRADRAAESVEVVINCS
MSMEG_3953|M.smegmatis_MC2_155 IDLERLTGIRERRVSLGEDDSYSLATKAALDCLEKADRSADSVEVVINCS
* ***: **.: :: : ::* * .: * :: *: :
MAV_4612|M.avium_104 STHFLQ------TPACGPAVAAALGATGVPAFDISAGCAGFGYALGVAAD
MUL_0632|M.ulcerans_Agy99 STHFLQ------TPACAPIVAAALGCQNVPAFDISAGCSGFGHALGIAAD
Mb0547c|M.bovis_AF2122/97 NTHFLQ------TPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAAD
Rv0533c|M.tuberculosis_H37Rv NTHFLQ------TPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAAD
MAB_1141c|M.abscessus_ATCC_199 STHYLQ------TPASAPAVATALGAQGVPAFDLSAGCAGFGYAVGVAGD
Mflv_2540|M.gilvum_PYR-GCK ITKFRDGLTQWMEPTMSAAVARAIGAEHAMTFDLSNACAGMLTGATVLNN
MMAR_3474|M.marinum_M ITKFRGGLTQWLEPSMSSAVARGIGAHRAMTFDVSNACAGMLTGVTILNN
TH_1179|M.thermoresistible__bu ITKFRDGLTQWLEPPMSTAVARAIGADTAMTFDLSNACAGMLTGVSILNN
MSMEG_3953|M.smegmatis_MC2_155 ITKFHGGLTQYLEPTMSSDVAHAIGARDAMTFDISNACAGMLTGVMVLNT
*:: *. .. ** .:*. **:* .*:*: .
MAV_4612|M.avium_104 MVRGGTAGKVLVLGSEKLSPTVDMTDRSNCFIFADGAAGVVVGETPTQGI
MUL_0632|M.ulcerans_Agy99 MIRGGSAATILVIGTEKLSPTVDMTDRSNCFIFVDGAASVLVGHSPIQGI
Mb0547c|M.bovis_AF2122/97 MIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGI
Rv0533c|M.tuberculosis_H37Rv MIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGI
MAB_1141c|M.abscessus_ATCC_199 MIRGGSASKVLVIGSEKLSPALDMTDRGNCFIFGDGAGAVVVGETAEQGI
Mflv_2540|M.gilvum_PYR-GCK WIRQGTVQRGLVVSGEYISQLGQNAARHIRSIMSKELACLTLGDAGAALL
MMAR_3474|M.marinum_M WIRQGVVERGLVVSGEYISQLSHNAARHIRNIMSKELASLTLGDAGAALL
TH_1179|M.thermoresistible__bu WIRQGVVERGMVVSGEYISQLTANAAQHIRTIMSKELASLTLGDAGAALL
MSMEG_3953|M.smegmatis_MC2_155 WIRQGLVARGMVVSGEYISQLGQNAAKHIRTVLSKELASLTLGDAGAALL
:* * . :*:. * :* : :: . . : :*.: :
MAV_4612|M.avium_104 GPTVWGS--DGTQATAIRQDIDWMDYLDRP---TGPRPFLRLEGSAVFRW
MUL_0632|M.ulcerans_Agy99 GPTVWGS--DGEQAAAIRQDIDWISHAENP---AGPRPFLRMEGTAVFRW
Mb0547c|M.bovis_AF2122/97 GPTVAGS--DGEQADAIRQDIDWITFAQNP---SGPRPFVRLEGPAVFRW
Rv0533c|M.tuberculosis_H37Rv GPTVAGS--DGEQADAIRQDIDWITFAQNP---SGPRPFVRLEGPAVFRW
MAB_1141c|M.abscessus_ATCC_199 GPTVWGS--DGSQSNAIRQDIDWMDFAAAPDP-EGPRPYLRIEGTSVFRW
Mflv_2540|M.gilvum_PYR-GCK FERAPADSAAGISLAGFTTVADHSRLCLAYPKGDDPGARMFTDSRGIQRA
MMAR_3474|M.marinum_M LERAPVG-SAGIALAGFTTVADYSRLCLAYPRGHDPGARMFTNARAIHQA
TH_1179|M.thermoresistible__bu LERAYPG-SGSIRLSGFTTIADHSRLCLAYPKGPEPGARMFTDSRGIQRA
MSMEG_3953|M.smegmatis_MC2_155 LERVPAG-GSGITLAGFTTIADYSRLCLAYPKGRDPGARMFTDSRAIHRA
. . . .: * * . : :. .: :
MAV_4612|M.avium_104 AAFEMGKVGQQAMDAAGVRPDEIDVFLPHQANSRIN----EILAKSLELR
MUL_0632|M.ulcerans_Agy99 AAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRIN----ELLTKNLQLR
Mb0547c|M.bovis_AF2122/97 AAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELLVKNLQLR
Rv0533c|M.tuberculosis_H37Rv AAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELLVKNLQLR
MAB_1141c|M.abscessus_ATCC_199 AAFEMGKVGQRAMEAAKVGPEQIDVFVPHQANTRIN----ELLAKNLHLR
Mflv_2540|M.gilvum_PYR-GCK AIAATPYLLHEVLDAAGISIGDIDHVITHQTSARAIRKGMAALTESFGGG
MMAR_3474|M.marinum_M AMANTPLLLEEVLETAGISIHDIDHVITHQTSARAIRKGMAKMSEAFGDK
TH_1179|M.thermoresistible__bu AIAATPVLLQEVLDQTGLSIHDIDHVITHQTSARAIRKGMRRIADEFGGT
MSMEG_3953|M.smegmatis_MC2_155 AITNTPVLLREVLDTAGISIDDIDHVITHQTSARAIKKGMAVMAAEFGDH
* : ...:: : : :** .:.**:.:* : :
MAV_4612|M.avium_104 PDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGYGAGLSY
MUL_0632|M.ulcerans_Agy99 PDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIGYGAGLSY
Mb0547c|M.bovis_AF2122/97 PDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSY
Rv0533c|M.tuberculosis_H37Rv PDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSY
MAB_1141c|M.abscessus_ATCC_199 ADAVIANDIEHTGNTSAASVPLAMETLLSTGAAKPGDLALLIGYGAGLSY
Mflv_2540|M.gilvum_PYR-GCK PRHDAVITVDRYGNTASTTHTVALVEELEAGRIRAGETIALIALASGLEI
MMAR_3474|M.marinum_M PRHDAVITVDRYGNTASTTHTVALIEELTAGRIVAGERIALIALASGLEI
TH_1179|M.thermoresistible__bu PAHDAVITVDKYGNTASTTHTVALVDELEAGGIAPGETIALIALASGLEI
MSMEG_3953|M.smegmatis_MC2_155 PRHDAVITVDRYGNTASTTHTVALIEELEARRIEPGETVALIALASGLEI
. . ::: ***:::: .:*: * : .*: **. .:**.
MAV_4612|M.avium_104 AAQVVRLPPG---------
MUL_0632|M.ulcerans_Agy99 AAQVVRMPNS---------
Mb0547c|M.bovis_AF2122/97 AAQVVRMPKG---------
Rv0533c|M.tuberculosis_H37Rv AAQVVRMPKG---------
MAB_1141c|M.abscessus_ATCC_199 AAQVVRMPPVPFE------
Mflv_2540|M.gilvum_PYR-GCK GVVLLTLDEELVNRYGHRD
MMAR_3474|M.marinum_M GIVLLTLDEEMVSRYGHSD
TH_1179|M.thermoresistible__bu GIVLLTLDEEMVGRHGNRG
MSMEG_3953|M.smegmatis_MC2_155 GIHLADR------------
. :